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Gc-Ms Profiling, Antioxidant, Antimicrobial Activities, Dna Cleavage Effect Ofsymphytum Aintabicum Hub.-Mor. & Wickens (Boraginaceae) And Its Anticancer Activityon Mcf-7 Cell Line, Alevcan Kaplan Jan 2021

Gc-Ms Profiling, Antioxidant, Antimicrobial Activities, Dna Cleavage Effect Ofsymphytum Aintabicum Hub.-Mor. & Wickens (Boraginaceae) And Its Anticancer Activityon Mcf-7 Cell Line, Alevcan Kaplan

Turkish Journal of Botany

Symphytum species, generally known as comfrey, have been used for ancient times in folk medicine for wounds, bone breakages, rheumatism, liver problems, and innumerable potentialities. However, many of the species belonging to the genus Symphytum have not been analyzed with scientific methods and principles yet. Therefore, this work is a guide for determining and researching the main gaps in the literature. In this study, MeOH and petroleum ether (PE) extracts of Symphytum aintabicum Hub.-Mor. & Wickens were analyzed for their biological activities and GC-MS analysis, antioxidant, antimicrobial activities, DNA cleavage effect, and anticancer activity on the MCF-7 human breast cell …


Screening Of Cytotoxicity And Dna Topoisomerase Iia Inhibitory Activity Of Turkish Onosma Species, Özge Güzel, Seda Duman, Si̇nem Yilmaz, Çi̇ğdem Karakoyun, Demet Kul, Ademi̇ Fahri̇ Pi̇rhan, Erdal Bedi̇r Jan 2021

Screening Of Cytotoxicity And Dna Topoisomerase Iia Inhibitory Activity Of Turkish Onosma Species, Özge Güzel, Seda Duman, Si̇nem Yilmaz, Çi̇ğdem Karakoyun, Demet Kul, Ademi̇ Fahri̇ Pi̇rhan, Erdal Bedi̇r

Turkish Journal of Botany

Onosma L., the largest genus of Boraginaceae, is represented by 105 species in Turkey with an endemism rate of 52%. Phytochemical studies indicate that Boraginaceae plants mainly comprise naphthoquinones with a wide range of biological activities including anticancer, antiinflammatory, wound healing, and antioxidant effects. However, few taxa of the genus Onosma have been investigated in detail for their bioactivities. Considering the high rate of endemism and an inadequate number of bioactivity screening studies in literature, we aimed to evaluate the cytotoxic effects and topoisomerase inhibitory activities of some Onosma species growing in southwestern Turkey. Here, we describe a comprehensive cytotoxic …


Anticancer, And Antioxidant Activities Of Royal Jelly On Ht-29 Colon Cancer Cells Andmelissopalynological Analysis, Adnan Ayna, Abdullah Tunç, Seda Nur Özbolat, Aydin Şükrü Bengü, Gürkan Aykutoğlu, Deni̇z Canli, Ridvan Polat, Mehmet Çi̇ftci̇, Ekrem Darendeli̇oğlu Jan 2021

Anticancer, And Antioxidant Activities Of Royal Jelly On Ht-29 Colon Cancer Cells Andmelissopalynological Analysis, Adnan Ayna, Abdullah Tunç, Seda Nur Özbolat, Aydin Şükrü Bengü, Gürkan Aykutoğlu, Deni̇z Canli, Ridvan Polat, Mehmet Çi̇ftci̇, Ekrem Darendeli̇oğlu

Turkish Journal of Botany

Royal jelly (RJ) is reflecting the flora around the apiaries as a result of the foraging activity of honeybees and therefore, pollen analysis could be used to verify its botanical/geographical origin. Colon cancer treatment by means of chemotherapeutics agents reflects a substantial problem for the organism due to high toxicity to other viable cells of the body. To explore a chemopreventive approach to enhancing colon cancer treatment efficacy, the antioxidant and antiproliferative effects of RJ in HT-29 colon cancer cells were assessed. Cell proliferation was performed by WST-1 assay, index of apoptosis was calculated by TUNEL Assay, antioxidant activities were …


Cover And Contents Jan 2021

Cover And Contents

Turkish Journal of Botany

No abstract provided.


Contributions To The Turkish Oribatid Mite Fauna (Acari: Oribatida) From Sakarya Andyozgat Provinces, Sedat Per, Kübra Çubukçu, Ayşe Toluk, Nusret Ayyildiz Jan 2021

Contributions To The Turkish Oribatid Mite Fauna (Acari: Oribatida) From Sakarya Andyozgat Provinces, Sedat Per, Kübra Çubukçu, Ayşe Toluk, Nusret Ayyildiz

Turkish Journal of Zoology

This study deals with the data on Turkish records of oribatid mites that play an important role in decomposition of organic matter, nutrient cycling, and soil formation. Oribatid mites in litter, lichen, moss, and soil collected from Sakarya and Yozgat provinces were sampled between 2014 and 2020. Standard methods were used for extraction, detection, preservation, and preparation of mites from the material collected from study area. Five oribatid mites were for the first time recorded from Turkey, namely Mesotritia (Mesotritia) nuda (Berlese, 1887) (Oribotritiidae), Hoplophorella (Rhacaplacarus) ortizi (Pérez-Íñigo, 1970) (Phthiracaridae), Eremaeus translamellatus Hammer, 1952 (Eremaeidae), Oribatella (Oribatella) foliata Krivolutsky, 1974 …


Ant Fauna (Hymenoptera: Formicidae) Of Central Anatolian Region Of Turkey, Kadri̇ Kiran, Celal Karaman Jan 2021

Ant Fauna (Hymenoptera: Formicidae) Of Central Anatolian Region Of Turkey, Kadri̇ Kiran, Celal Karaman

Turkish Journal of Zoology

The Central Anatolian part of Turkey was investigated with the aim of determining its Formicidae fauna. Specimens were collected by hand sampling and pitfall traps in 24 habitats in 383 different localities in Central Anatolia Region during 2001-2016. As a result, 137 species belonging to 34 genera were determined. Messor incorruptus Kuznetsov-Ugamsky, 1929 and Ponera testacea Emery, 1895 are new records for Turkish ant fauna. We excluded four species, Camponotus sylvaticus (Oliver, 1792), Messor meridionalis (André, 1883), Proformica striaticeps (Forel, 1911) and Tapinoma nigerrimum (Nylander, 1856), from Turkish ant fauna due to recent taxonomic data and distribution pattern. With these …


Insectum Non Grata: The Harlequin Ladybird, Harmonia Axyridis (Pallas, 1773)(Coleoptera, Coccinellidae) In Turkey, Ahmet Karataş, Ayşegül Karataş, Ni̇zametti̇n Yavuz, Eli̇f Deni̇z Ülker, Özgür Koçak, Burak Akbaba Jan 2021

Insectum Non Grata: The Harlequin Ladybird, Harmonia Axyridis (Pallas, 1773)(Coleoptera, Coccinellidae) In Turkey, Ahmet Karataş, Ayşegül Karataş, Ni̇zametti̇n Yavuz, Eli̇f Deni̇z Ülker, Özgür Koçak, Burak Akbaba

Turkish Journal of Zoology

The Harlequin Ladybird, Harmonia axyridis (Pallas, 1773), is native to Eastern Asia but it has been introduced to many countries in Africa, America, and Eurasia. In Turkey, H. axyridis is one of the most fast-spreading invasive alien species. Since the collection of the first specimens in 2010, H. axyridis spread almost all over the country. The species spreads fast in Turkey according to the new records, obtained originally from the field studies and the citizen science data. It was recorded for the first time from 19 of 81 Turkish provinces (Ankara, Antalya, Balıkesir, Bolu, Bursa, İstanbul, İzmir, Karaman, Kastamonu, Kırklareli, …


Capoeta Kosswigi Karaman, 1969 A Junior Synonym Of Capoeta Damascina(Valenciennes, 1842) (Teleostei: Cyprinidae), Erdoğan Çi̇çek, Soheil Eagderi, Burak Seçer, Sevi̇l Sungur Jan 2021

Capoeta Kosswigi Karaman, 1969 A Junior Synonym Of Capoeta Damascina(Valenciennes, 1842) (Teleostei: Cyprinidae), Erdoğan Çi̇çek, Soheil Eagderi, Burak Seçer, Sevi̇l Sungur

Turkish Journal of Zoology

Capoeta kosswigi was described from Lake Van basin, Turkey, being close to C. damascina and C. umbla. It is distinguished from them by a pointed snout and a small horseshoe-shaped mouth, and differing from C. damascina by having smaller scales, and from the C. umbla by processing larger scales. In this study, we tested the suggested synonymy hypothesis of C. kosswigi and C. damascina by comparing the morphometric and meristic data. The results revealed that all morphometric and meristic characters of C. kosswigi overlap with those of C. damascina. In line with previous molecular studies that COI, cytb and 16S …


Value Of Strain-Wave Sonoelastography As An Imaging Modality In Assessment Ofbenign Acute Myositis In Children, Ayşe Seçi̇l Ekşi̇oğlu, Ayla Akca Çağlar, Seda Kaynak Şahap, Can Demi̇r Karacan, Ni̇lden Tuygun Jan 2021

Value Of Strain-Wave Sonoelastography As An Imaging Modality In Assessment Ofbenign Acute Myositis In Children, Ayşe Seçi̇l Ekşi̇oğlu, Ayla Akca Çağlar, Seda Kaynak Şahap, Can Demi̇r Karacan, Ni̇lden Tuygun

Turkish Journal of Medical Sciences

Background/aim: Although sonoelastography is applied in assessment of many organs, studies for evaluation of muscles are very few in number and are mostly limited to adults. With this prospective study, we aimed to evaluate the value of sonoelastography in assessment of influenza related benign acute myositis in children. Materials and methods: This study enrolled 25 patients with a clinical diagnosis of benign acute childhood myositis (BACM) and 25 age and sex-matched healthy controls. All patients presented to our emergency department with the complaint of inability to walk and had increased serum creatine kinase (CK) levels. All patients underwent strain elastography …


Evaluation Of The Effects Of Locally Applied Rosuvastatin On Bone Formation In A Threedimensional Reconstruction Rabbit Xenograft Model, Taha Özer, Alper Aktaş, Canseda Avağ, Ayşegül Firat, Mert Ocak, Fevzi̇ye Fi̇gen Kaymaz, Hakan Hamdi̇ Çeli̇k Jan 2021

Evaluation Of The Effects Of Locally Applied Rosuvastatin On Bone Formation In A Threedimensional Reconstruction Rabbit Xenograft Model, Taha Özer, Alper Aktaş, Canseda Avağ, Ayşegül Firat, Mert Ocak, Fevzi̇ye Fi̇gen Kaymaz, Hakan Hamdi̇ Çeli̇k

Turkish Journal of Medical Sciences

Background/aim: Guided bone regeneration (GBR) is commonly performed to repair bone defects, and rigid occlusive titanium barriers play a vital role in bone formation in regions with no prior bone tissue. The statin, rosuvastatin (RSV), strongly affects bone apposition when applied locally. Here, we aimed to evaluate the anabolic effects of locally applied RSV with a xenograft placed on rabbit calvaria. Materials and methods: Two rigid occlusive titanium caps were used in 16 rabbits after decorticating the calvarial bone. In the control group, the area under the cap was filled with a xenograft, while in the RSV group, a xenograft …


Perspectives For Immune Plasma Treatment Of Covid-19, Başak Sayinalp, Olgu Erki̇n Çinar, İbrahi̇m Celaletti̇n Haznedaroğlu Jan 2021

Perspectives For Immune Plasma Treatment Of Covid-19, Başak Sayinalp, Olgu Erki̇n Çinar, İbrahi̇m Celaletti̇n Haznedaroğlu

Turkish Journal of Medical Sciences

Background/aim: The SARS-CoV-2 infection was declared as a pandemic by the World Health Organization (WHO) on March 11, 2020, and the death toll from COVID-19, which is the disease caused by SARS-CoV-2, has already surpassed that of many previous epidemics. A wide variety of treatment options are being considered for COVID-19, but there is still no definitive treatment or vaccine. This study aims to explain the background of convalescent plasma (CP) treatment and its relations with COVID-19 immunity, to define ideal treatment procedures, and to reveal present and future perspectives in the light of the rapidly growing data. Immunological basis …


Comparison Of The Clinical And Sonographic Effects Of Ultrasound Therapy, Extracorporealshock Wave Therapy, And Kinesio Taping In Lateral Epicondylitis, Tarik Özmen, Sali̇h Süha Koparal, Özlem Karataş, Fi̇li̇z Eser, Bülent Özkurt, Tuba Ümi̇t Gafuroğlu Jan 2021

Comparison Of The Clinical And Sonographic Effects Of Ultrasound Therapy, Extracorporealshock Wave Therapy, And Kinesio Taping In Lateral Epicondylitis, Tarik Özmen, Sali̇h Süha Koparal, Özlem Karataş, Fi̇li̇z Eser, Bülent Özkurt, Tuba Ümi̇t Gafuroğlu

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to compare the clinical and sonographic effects of the ultrasound (US) therapy, extracorporeal shock wave therapy (ESWT), and Kinesio taping (KT) in the lateral epicondylitis (LE). Materials and methods: A total of 40 patients with LE were included in the present study. The patients were randomly assigned to 3 treatment groups: US (n = 13), ESWT (n = 14), and KT (n = 13) groups. Results: The visual analog scale (VAS) scores significantly decreased in all groups (P < 0.05). Grip strength significantly increased after 8 weeks in only the KT group (P < 0.05). The Patient-Rated Tennis Elbow Evaluation Scale (PRTEE) scores significantly decreased after 2 weeks and after 8 weeks in the US group and ESWT groups, and after 8 weeks in the KT group (P < 0.05). Common extensor tendon (CET) thicknesses significantly decreased after 8 weeks in only the ESWT group (P < 0.05). Conclusion: The US therapy, KT, and ESWT are effective in reducing pain and improving functionality. However, none of these treatment methods were found to be superior to others in reducing the pain and improving functionality.


Magnetic Resonance Imaging Histogram Analysis Of Corpus Callosum In A Functionalneurological Disorder, Sema Baykara, Murat Baykara, Osman Mermi̇, Hanefi̇ Yildirim, Murad Atmaca Jan 2021

Magnetic Resonance Imaging Histogram Analysis Of Corpus Callosum In A Functionalneurological Disorder, Sema Baykara, Murat Baykara, Osman Mermi̇, Hanefi̇ Yildirim, Murad Atmaca

Turkish Journal of Medical Sciences

Background/aim: The aim of the present study was to examine and compare the corpus callosum (CC) via histogram analysis (HA) on T1-weighted MR images of patients diagnosed with Functional Neurological Disorder (FND) and healthy controls. Materials and methods: The study group included 19 female patients diagnosed with FND, and the control group included 20 healthy subjects. All participants were scanned with a 1.5 T MR scanner. A high-resolution structural image of the entire brain was obtained with sagittal 3D spiral fast spin echo T1-weighted images. Gray level intensity, standard deviation of the histogram, entropy, uniformity, skewness, and kurtosis values were …


Point-Of-Care Ultrasound Assessment Of The Inferior Vena Cava Distensibility Index Inmechanically Ventilated Children In The Operating Room, Riza Di̇nçer Yildizdaş, Özden Özgür Horoz, Ahmet Yöntem, Faruk Eki̇nci̇, Vahi̇de Nagehan Aslan, Demet Lafli Tunay, Murat Türkeün Ilginel Jan 2021

Point-Of-Care Ultrasound Assessment Of The Inferior Vena Cava Distensibility Index Inmechanically Ventilated Children In The Operating Room, Riza Di̇nçer Yildizdaş, Özden Özgür Horoz, Ahmet Yöntem, Faruk Eki̇nci̇, Vahi̇de Nagehan Aslan, Demet Lafli Tunay, Murat Türkeün Ilginel

Turkish Journal of Medical Sciences

Background and aim: Point-of-care ultrasound imaging of the inferior vena cava distensibility index is a potential indicator for determining fluid overload and dehydration in the mechanically ventilated patients. Data on inferior vena cava distensibility index and inferior vena cava distensibility variability are limited in mechanically ventilated pediatric patients. That is why our aim in this study was to measure inferior vena cava distensibility index and to obtain mean values in pediatric patients, ventilated in the operating room before the ambulatory surgical procedure started. Materials and methods: This crosssectional study was performed between February 2019 and February 2020. Ultrasonographic measurements were …


Prevalence Of Comorbidities And Associated Factors In Acromegaly Patients In The Turkishpopulation, Mustafa Can, Muhammet Kocabaş, İlker Çordan, Hati̇ce Çalişkan Burgucu, Meli̇a Karaköse, Mustafa Kulaksizoğlu, Feridun Karakurt Jan 2021

Prevalence Of Comorbidities And Associated Factors In Acromegaly Patients In The Turkishpopulation, Mustafa Can, Muhammet Kocabaş, İlker Çordan, Hati̇ce Çalişkan Burgucu, Meli̇a Karaköse, Mustafa Kulaksizoğlu, Feridun Karakurt

Turkish Journal of Medical Sciences

Background/aim: The presence of comorbidities in patients with acromegaly causes an increase in morbidity and/or mortality and a decrease in quality of life. In this study, we aimed to investigate the demographic, clinical and laboratory features, prevalence of acromegaly-related comorbidities, and factors associated with these comorbidities in patients with acromegaly. Materials and methods: In the study, 96 patients who were followed up with the diagnosis of acromegaly were included. Clinical, laboratory and imaging features, and accompanying comorbidities of the patients were recorded from the patient files. Results: Of the patients included in the study, 63 (65.6%) were female and 33 …


Comparison Of Frozen-Thawed Embryo Transfer Protocols In Patients With Previouscycle Cancellation Due To Uterine Peristalsis: A Pilot Study, İlknur Selvi̇, Mehmet Erdem, Erhan Demi̇rdağ, Müni̇re Funda Cevher Akdulum, Cengi̇z Karakaya, Ahmet Erdem Jan 2021

Comparison Of Frozen-Thawed Embryo Transfer Protocols In Patients With Previouscycle Cancellation Due To Uterine Peristalsis: A Pilot Study, İlknur Selvi̇, Mehmet Erdem, Erhan Demi̇rdağ, Müni̇re Funda Cevher Akdulum, Cengi̇z Karakaya, Ahmet Erdem

Turkish Journal of Medical Sciences

Background/aim: To investigate the optimal protocol for frozen-thawed embryo transfer (FET) cycles in patients who previously had a cycle cancellation due to uterine peristalsis (UP). Materials and methods: Thirty-four patients with previous embryo transfer (ET) cancellation due to UP during artificial cycle (AC) were included retrospectively. In the proceeding cycle, endometrium was prepared with AC (n: 23) in AC-FET group or with stimulated cycle that contains letrozole (L) (n: 11) in L-FET group. Intravenous bolus dose of 6.75 mg atosiban (Tractocile; Ferring Pharmaceuticals, Switzerland) injection was performed to all patients of AC-FET group due to UP ≥ 4/min on the …


The Effect Of Ankaferd Blood Stopper On Liver Damage In Experimental Obstructivejaundice, Koray Koşmaz, Abdullah Durhan, Marlen Süleyman, Yilmaz Ünal, Mustafa Taner Bostanci, Tuğba Yi̇ği̇t Haskaraca, Can Ersak, Mehmet Şeneş, İlknur Alkan Kuşabbi̇, Eylem Pinar Eser, Sema Hücümenoğlu Jan 2021

The Effect Of Ankaferd Blood Stopper On Liver Damage In Experimental Obstructivejaundice, Koray Koşmaz, Abdullah Durhan, Marlen Süleyman, Yilmaz Ünal, Mustafa Taner Bostanci, Tuğba Yi̇ği̇t Haskaraca, Can Ersak, Mehmet Şeneş, İlknur Alkan Kuşabbi̇, Eylem Pinar Eser, Sema Hücümenoğlu

Turkish Journal of Medical Sciences

Background/aims: To evaluate the potential protective effects of Ankaferd blood stopper (ABS) in an experimental obstructive jaundice (OJ) model. Materials and methods: The study included 26 female rats, which were divided into 3 groups. The sham group, consisting of 10 rats, (group 1) only received solely laparotomy. In the control group, consisting of 8 rats, (group 2), ligation was applied to the biliary tract and no treatment was implemented. In the treatment group, consisting of 8 rats, (group 3), following ligation of biliary tract, 0.5 mL/day ABS was given for 10 days. Liver tissue and blood samples were taken for …


Effects Of The Covid-19 Pandemic On Psychology And Disease Activity In Patients Withankylosing Spondylitis And Rheumatoid Arthritis, Şaki̇r Gica, Yasemi̇n Akkubak, Zaki̇re Kübra Aksoy, Adem Küçük, Erkan Cüre Jan 2021

Effects Of The Covid-19 Pandemic On Psychology And Disease Activity In Patients Withankylosing Spondylitis And Rheumatoid Arthritis, Şaki̇r Gica, Yasemi̇n Akkubak, Zaki̇re Kübra Aksoy, Adem Küçük, Erkan Cüre

Turkish Journal of Medical Sciences

Background/aim: The COVID-19 outbreak is known to increase stress levels of most patients with chronic diseases. Patients with ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are highly susceptible to environmental stress. In the current study, we aimed to determine how the COVID-19 pandemic psychologically affected patients with chronic progressive diseases such as AS and RA and the effects of these psychological factors on disease activity. Materials and methods: Age and sex-matched patients with AS (n = 80), RA (n = 80), and healthy controls (n = 80) were included in the study. All participants were evaluated with the "Perceived COVID-19 …


Attention-Deficit Hyperactivity Disorder Symptoms And Quality Of Life In Female Patientswith Fibromyalgia, Gözde Türkoğlu, Yavuz Selvi̇ Jan 2021

Attention-Deficit Hyperactivity Disorder Symptoms And Quality Of Life In Female Patientswith Fibromyalgia, Gözde Türkoğlu, Yavuz Selvi̇

Turkish Journal of Medical Sciences

Background/aim: The present study aimed to determine the association between attention-deficit hyperactivity disorder (ADHD) symptoms severity, fibromyalgia (FM) severity, and QoL. Materials and methods: While the FM group consisted of 113 (74%) patients, the control group consisted of 40 (26%) individuals. FM symptom severity, ADHD symptom severity, and QoL were evaluated using the fibromyalgia impact questionnaire (FIQ), adult ADHD self-report scale (ASRS), and World Health Organization quality of life scale-brief version (WHOQOL-BREF), respectively. Results: It was found that the FM group had significantly higher scores on the ASRS than the control group (p < 0.05). There was a significant difference in FIQ scores and three WHOQOL-BREF domain scores between the FM alone and comorbid FM/high probability of ADHD groups (p < 0.05). We found a negative correlation between ASRS total scores and all other scale scores (except for the social relationships domain score of the WHOQOL-BREF) and a positive correlation between ASRS total scores and FIQ scores in FM patients. ADHD scores would mediate the relationship between depression severity and QoL. Conclusions: Our findings indicated that the presence of ADHD symptoms was related to greater FM symptom severity and poorer QoL. Also, ADHD scores would mediate the relationship between depression severity and QoL.


Utilization Of Biotechnological Drugs In Rare Diseases Requiring The Use Of Off-Label Drugsin Children In Turkey, Neri̇man İpek Kirmizi, Volkan Aydin, Nari̇n Akici, Banu Bayar, Ahmet Akici Jan 2021

Utilization Of Biotechnological Drugs In Rare Diseases Requiring The Use Of Off-Label Drugsin Children In Turkey, Neri̇man İpek Kirmizi, Volkan Aydin, Nari̇n Akici, Banu Bayar, Ahmet Akici

Turkish Journal of Medical Sciences

Background/aim: Pediatric patients, especially those with rare diseases, represent a population that has a high tendency towards offlabel drug use (OLDU) and needs a more careful practice of pharmacotherapy than in adults. We aimed to investigate biotechnological drug use in children with rare diseases requiring OLDU. Materials and methods: This retrospective study examined all single-diagnosed OLDU applications (n = 5792) for 4992 children (


Effects Of Intracerebroventricularly Administered Opioid Peptide Antagonistson Tissue Glycogen Levels In Rats After Exercise, Ayşe Şebnem İlhan, Şevi̇n Güney, Si̇bel Di̇ncer Jan 2021

Effects Of Intracerebroventricularly Administered Opioid Peptide Antagonistson Tissue Glycogen Levels In Rats After Exercise, Ayşe Şebnem İlhan, Şevi̇n Güney, Si̇bel Di̇ncer

Turkish Journal of Medical Sciences

Background/aim: Physical exercise is a state of physiological stress that requires adaptation of the organism to physical activity. Glycogen is an important and essential energy source for muscle contraction. Skeletal muscle and liver are two important glycogen stores, and the energy required to maintain exercise in rodents are provided by destruction of this glycogen depot. In this study, the effects of endogenous opioid peptide antagonism at the central nervous system level on tissue glycogen content after exhaustive exercise were investigated. Materials and methods: Rats had intracerebroventricularly (icv) received nonspecific opioid peptide receptor antagonist, naloxone (50 μ/10 μL in saline) and …


Role Of Frailty In Prediction Of Hospitalized Older Adult Patient's Outcomes: A Prospective Study, Maryam Chehrehgosha, Reza Fadaye Vatan, Mahtab Alizadeh Khoei, Farshad Sharifi, Reyhaneh Aminalroaya, Zahra Vahabi, Abolfazl Zendedel, Hamidreza Hekmat Jan 2021

Role Of Frailty In Prediction Of Hospitalized Older Adult Patient's Outcomes: A Prospective Study, Maryam Chehrehgosha, Reza Fadaye Vatan, Mahtab Alizadeh Khoei, Farshad Sharifi, Reyhaneh Aminalroaya, Zahra Vahabi, Abolfazl Zendedel, Hamidreza Hekmat

Turkish Journal of Medical Sciences

Background/aim: Frailty is associated with an increased risk of negative short-term and long-term hospital outcomes. This study aimed to evaluate the role of frailty in predicting readmission, length of stay, and quality of life in the hospitalized older adults. Materials and methods: This observational study was conducted at Ziaiyan Hospital, Tehran, Iran. In total, 304 participants (65-85 years), were enrolled through the inclusion criteria from August to December 2019. The frailty index (FI) was assessed by the minimum data set-home care. Readmission was obtained through telephone interviews. The length of stay was gathered by the patient's hospital records, and the …


Evaluation Of Serum Neutrophil Gelatinase-Associated Lipocalin (Ngal), Asymmetricdimethylarginine (Adma) And Symmetric Dimethylarginine (Sdma) Levels, And Theirrelations With Disease Type And Activity In Inflammatory Bowel Diseases, Hüseyi̇n Korkmaz, Mehmet Asil, Tuncer Temel, Bahadir Öztürk, Levent Kebapcilar Jan 2021

Evaluation Of Serum Neutrophil Gelatinase-Associated Lipocalin (Ngal), Asymmetricdimethylarginine (Adma) And Symmetric Dimethylarginine (Sdma) Levels, And Theirrelations With Disease Type And Activity In Inflammatory Bowel Diseases, Hüseyi̇n Korkmaz, Mehmet Asil, Tuncer Temel, Bahadir Öztürk, Levent Kebapcilar

Turkish Journal of Medical Sciences

Background/aim: Inflammatory bowel disease (IBD) mainly encompass two entities called ulcerative colitis (UC) and Crohn's disease (CD), both of which are chronic, progressive and, inflammatory conditions of the gastrointestinal tract. Various indicators and noninvasive markers have been sought and used in IBD patients to help assessing disease activity and treatment effectiveness although none of them are proven to yield definite results in full correlation with the clinical, endoscopic, and histopathological examinations. The aim of the current study was to investigate the relationship of serum neutrophil gelatinase-associated lipocalin (NGAL), asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA) levels with disease type and …


New Additions To Turkish Mycota From Ankara, Balıkesir, And Kütahya Provinces, Deni̇z Altuntaş, Fuat Bozok, Hatira Taşkin, Şanli Kabaktepe, Hakan Alli, Ilgaz Akata Jan 2021

New Additions To Turkish Mycota From Ankara, Balıkesir, And Kütahya Provinces, Deni̇z Altuntaş, Fuat Bozok, Hatira Taşkin, Şanli Kabaktepe, Hakan Alli, Ilgaz Akata

Turkish Journal of Botany

The current research was conducted on the fungal materials collected from Ankara, Balıkesir, and Kütahya provinces between 2015 and 2019. As a result of the field and laboratory studies, Conocybe dentatomarginata, Entoloma lampropus, Lactarius lilacinus, Otidea nannfeldtii and Sarcopeziza sicula are reported for the first time from Turkey based on macro- and micromorphological studies and internal transcribed spacer (ITS) rDNA-based molecular phylogeny. Descriptions of new records are provided together with photos showing their macro and micro-morphology.


Cover And Contents Jan 2021

Cover And Contents

Turkish Journal of Botany

No abstract provided.


Applications Of Crispr/Cas9-Based Genome Editing In The Plant Biology, Yingzhuan Zheng, Qianqian Li, Mingwang Ye, Aie Cehn, Hongyang Wang Jan 2021

Applications Of Crispr/Cas9-Based Genome Editing In The Plant Biology, Yingzhuan Zheng, Qianqian Li, Mingwang Ye, Aie Cehn, Hongyang Wang

Turkish Journal of Botany

Clustered regularly interspaced short palindromic repeats/CRISPR-associated proteins (CRISPR/Cas) is an acquired immune system found in bacteria and archaea that can specifically silence or degrade a foreign single or double strand nucleic acid to protect it from infection. In recent years, the CRISPR/Cas9 system has rapidly been evolved into a genome editing technology, in which the Cas9 endonuclease can be targeted to specific DNA sequences by guide RNAs (gRNAs) that are easily programmable. Due to simplicity, specificity and high efficiency, CRISPR/Cas9 is gradually replacing other gene editing technologies and has been implemented in basic and applied plant sciences to boost yield, …


Evaluation Of Bermudagrass [Cynodon (L.) Rich] Accessions With Different Ploidy Levels, Cansu Bülbül, Songül Sever Mutlu, Nedi̇m Mutlu, Osman Gülşen Jan 2021

Evaluation Of Bermudagrass [Cynodon (L.) Rich] Accessions With Different Ploidy Levels, Cansu Bülbül, Songül Sever Mutlu, Nedi̇m Mutlu, Osman Gülşen

Turkish Journal of Botany

Eastern Mediterranean is considered as a center of diversity of


Impact Of Image Segmentation Techniques On Celiac Disease Classification Usingscale Invariant Texture Descriptors For Standard Flexible Endoscopic Systems, Manarbek Saken, Munkhtsetseg Banzragch Yağci, Nejat Yumuşak Jan 2021

Impact Of Image Segmentation Techniques On Celiac Disease Classification Usingscale Invariant Texture Descriptors For Standard Flexible Endoscopic Systems, Manarbek Saken, Munkhtsetseg Banzragch Yağci, Nejat Yumuşak

Turkish Journal of Electrical Engineering and Computer Sciences

Celiac disease (CD) is quite common and is a proximal small bowel disease that develops as a permanentintolerance to gluten and other cereal proteins in cereals. It is considered as one of the most di?icult diseases to diagnose.Histopathological evidence of small bowel biopsies taken during endoscopy remains the gold standard for diagnosis.Therefore, computer-aided detection (CAD) systems in endoscopy are a newly emerging technology to enhance thediagnostic accuracy of the disease and to save time and manpower. For this reason, a hybrid machine learning methodshave been applied for the CAD of celiac disease. Firstly, a context-based optimal multilevel thresholding technique wasemployed …


Automated Classification Of Bi-Rads In Textual Mammography Reports, Mostafa Boroumandzadeh, Elham Parvinnia Jan 2021

Automated Classification Of Bi-Rads In Textual Mammography Reports, Mostafa Boroumandzadeh, Elham Parvinnia

Turkish Journal of Electrical Engineering and Computer Sciences

The main purpose of this paper is to process key information in medical text records and also classifypatients, per different levels of breast imaging-reporting and data system (BI-RADS). The BI-RADS is a scheme for thestandardization of breast imaging reports. Therefore, medical text mining is employed to classify mammography reportssupported BI-RADS. In this research, a new method is proposed for automated BI-RADS classifications extraction fromtextual reports and improves the therapeutic procedures. At first, a mammography lexicon is employed for choosingkeywords from medical text reports. Word2vec and term frequency inverse document frequency (TFIDF) techniques areused for extracting features, finally, they are combined …


Design Of The Fractional Order Internal Model Controller Using The Swarmintelligence Techniques For The Coupled Tank System, Sateesh Kumar Vavilala, Vinopraba Thirumavalavan, Radhakrishnan Thota, Sivakumaran Natarajan Jan 2021

Design Of The Fractional Order Internal Model Controller Using The Swarmintelligence Techniques For The Coupled Tank System, Sateesh Kumar Vavilala, Vinopraba Thirumavalavan, Radhakrishnan Thota, Sivakumaran Natarajan

Turkish Journal of Electrical Engineering and Computer Sciences

The coupled tank system (comprising two tanks) is used in the chemical industries, water treatment plantsetc. Level control of the coupled tank system is a common problem in the process control industry. This work proposes afractional order internal model controller (FOIMC) with a higher order fractional filter for the level control of the coupledtank system. A first order plus delay time (FOPDT) model of the system is used in the controller design. FOIMC hasadvantages like robustness to changes in the system gain and extended stability margins. The proposed higher orderfractional filter makes the controller physically realizable and quickly roll off …