Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Life Sciences (5916)
- Medicine and Health Sciences (2313)
- Animal Sciences (2151)
- Physical Sciences and Mathematics (1962)
- Biology (1669)
-
- Medical Sciences (1464)
- Zoology (1302)
- Chemistry (1183)
- Botany (1118)
- Plant Sciences (1118)
- Agriculture (978)
- Forest Sciences (978)
- Veterinary Medicine (849)
- Computer Engineering (461)
- Computer Sciences (461)
- Electrical and Computer Engineering (461)
- Engineering (461)
- Mathematics (146)
- Earth Sciences (107)
- Physics (65)
- Keyword
-
- Turkey (608)
- Taxonomy (221)
- Oxidative stress (132)
- New records (121)
- New species (104)
-
- Apoptosis (93)
- Morphology (93)
- New record (91)
- Antioxidant (83)
- Distribution (80)
- Phylogeny (79)
- COVID-19 (78)
- Cytotoxicity (73)
- Growth (73)
- Biodiversity (72)
- Antimicrobial activity (71)
- Iran (71)
- 1 (67)
- Inflammation (66)
- 2 (63)
- Breast cancer (62)
- Fauna (61)
- Rat (61)
- Antioxidant activity (60)
- Genetic diversity (60)
- Gene expression (59)
- Antioxidant enzymes (48)
- Endemic (48)
- Antibacterial activity (47)
- Cancer (47)
- Publication Year
Articles 1531 - 1560 of 10500
Full-Text Articles in Entire DC Network
Phytochemical Potential And Associated Health Benefits Of Cucurbita Flower, Arya Gargi, Jyoti Singh, Prasad Rasane, Sawinder Kaur, Jaspreet Kaur, Chandra Mohan Mehta, Yogesh Gat, Ravish Choudhary
Phytochemical Potential And Associated Health Benefits Of Cucurbita Flower, Arya Gargi, Jyoti Singh, Prasad Rasane, Sawinder Kaur, Jaspreet Kaur, Chandra Mohan Mehta, Yogesh Gat, Ravish Choudhary
Turkish Journal of Agriculture and Forestry
Edible flowers are currently gaining popularity as the majority of the edible flower species have a nutritional profile that meets several dietary demands and the consumption of flowers as part of customary cuisine or alternative alchemy is reported in various cultures around the world. Pumpkin flowers are primarily consumed in some Asian and North American countries like India, China, Bangladesh, and Mexico, respectively. The pumpkin plant has served medicinally worldwide by treating wounds, cardiovascular disease, several types of cancers, gastrointestinal diseases, anemia, urinary tract infections and intestinal parasites, however, its flowers among the same line have also been therapeutically used …
Actinidia Deliciosa: A High-Resolution Mass Spectrometric Approach For The Comprehensive Characterization Of Bioactive Compounds, Mayya Razgonova, Alexsander Boyko, Yulia Zinchenko, Nadezhda Tikhonova, Andrey Sabitov, Alexander Mikhailovich Zakharenko, Kirill Golokhvast
Actinidia Deliciosa: A High-Resolution Mass Spectrometric Approach For The Comprehensive Characterization Of Bioactive Compounds, Mayya Razgonova, Alexsander Boyko, Yulia Zinchenko, Nadezhda Tikhonova, Andrey Sabitov, Alexander Mikhailovich Zakharenko, Kirill Golokhvast
Turkish Journal of Agriculture and Forestry
Actinidia deliciosa (A. Chev.) C.F. Liang & A.R& Ferguson, 1984 contains a large number of target analytes, which are biologically active compounds. HPLC-ion trap-MS/MS (tandem mass spectrometry) was used to identify target analytes in extracts of A. deliciosa (varieties Abbot, Alison, Bruno, Hayward, Monti), originating from the Adler's Branch of N.I. Vavilov All-Russian Institute of Plant Genetic Resources. Separately, the pulp of the kiwi fruit and its peel were analyzed for the composition of biologically active substances. The richest in the composition of active substances was indicators of the cultivar Monti. The results of initial studies revealed the presence of …
Production And Oenological Potential Of Riesling Variety Clones 49, 1091 And 1089, Tatjana Jovanovic-Cvetkovic, Rada Grbic, Borut Bosancic, Miljan Cvetkovic
Production And Oenological Potential Of Riesling Variety Clones 49, 1091 And 1089, Tatjana Jovanovic-Cvetkovic, Rada Grbic, Borut Bosancic, Miljan Cvetkovic
Turkish Journal of Agriculture and Forestry
Clonal selection in viticulture is based on genetic variability with the aim of creating superior plants (clones) that enable more economical production. The Riesling variety, with a long tradition of cultivation, has been the subject of extensive clonal selection and clones 49, 1089 and 1091 were created in France. During the two-year period (2016-2017), the productivity and oenological potential of Riesling clones 49, 1089 and 1091 in the agroclimatic conditions of Bosnia and Herzegovina were conducted. Significant differences between clones were found in the yield per vine (1.34-1.87 kg), ten skins weight (2.17-2.46 g) and mass of ten berries seeds …
Effect Of Postharvest Spermidine Treatments On Quality And Biochemical Properties Of Nectarine Fruits, Erdal Orman
Effect Of Postharvest Spermidine Treatments On Quality And Biochemical Properties Of Nectarine Fruits, Erdal Orman
Turkish Journal of Agriculture and Forestry
In this study, the effect of spermidine (SP) treatments at different doses after harvest on the changes in the pomological and biochemical contents of nectarine fruits was determined. The fruits were placed in cold storage (4 ± 0.5 °C and 90 ± 5% RH) for 30 days. Specific organic acids and phenolic compounds from biochemical compounds were analyzed by HPLC device. Weight loss and decay values, which are quality criteria of nectarine fruits, increased during storage compared to the harvest period. In this study, 1.0 mM SP application was found to be more successful in the preservation of visual quality …
Antioxidant, Antidiabetic, And Antihypertensive Effects Of Peptides From Some Quercus Species, Muhammed Yusuf Çağlar, Muhammet Arici
Antioxidant, Antidiabetic, And Antihypertensive Effects Of Peptides From Some Quercus Species, Muhammed Yusuf Çağlar, Muhammet Arici
Turkish Journal of Agriculture and Forestry
In the present study, the antihypertensive, antidiabetic, and antioxidant properties of oak peptides were determined in vitro. For this purpose, samples from most common oak species (Quercus coccifera, Quercus ilex, and Quercus cerris) were collected, the proteins were extracted and the bioactive properties of 48 different peptide fractions were monitored using a fast protein liquid chromatography. The results showed that acorn peptides had no remarkable antioxidant or antihypertensive effects. Comparing the bioactive peptides of all oak species, the peptides of Q. coccifera generally had higher DPP-IV inhibition activity than those of Q. cerris and Q. ilex. …
Standardization Of Vigour Test To Predict Field Emergence And Difference Of Seed Vigour Among Lentils (Lens Culinaris L.) Seed Lots, Negar Ebrahim Pour Mokhtari
Standardization Of Vigour Test To Predict Field Emergence And Difference Of Seed Vigour Among Lentils (Lens Culinaris L.) Seed Lots, Negar Ebrahim Pour Mokhtari
Turkish Journal of Agriculture and Forestry
Selecting seeds with high vigour eminently affects initial plant growth and determines plant stand. Various tests including electrical conductivity (EC), radicle emergence counts (RE), and standard germination (SG) tests were used to assess the vigour of eleven lentils (Lens culinaris L.) seed lots. Lentil seed lots with over 75% normal germination, were germinated with the use of an ISTA standard germination test. The radicle emergence (2 mm) was tallied at constant intervals from 24-120 h. The seed lots were sown in the fields and 40 days after sowing, the final seedling emergence was evaluated. The standard germination test demonstrated …
Assessment Of Genetic Variability And Genetic Parameters Of Morphological And Agro-Physiological Traits In Camelina Sativa (L.), Farshad Fallah, Danial Kahrizi, Abbas Rezaeizad, Alireza Zebarjadi, Leila Zarei, Hülya Doğan
Assessment Of Genetic Variability And Genetic Parameters Of Morphological And Agro-Physiological Traits In Camelina Sativa (L.), Farshad Fallah, Danial Kahrizi, Abbas Rezaeizad, Alireza Zebarjadi, Leila Zarei, Hülya Doğan
Turkish Journal of Agriculture and Forestry
The present investigation was done to evaluate genetic variability and estimation of genetic parameters of morphological and agro-physiological traits in Camelina sativa (L.) using biometrical genetic techniques. For this purpose, 136 Camelina doubled haploid line genotypes were assessed in a randomized complete blocks design with three replicates in the Field Research, Razi University, Kermanshah, Iran, during the 2014-2015 cropping season. The results of the analysis of variance showed significant differences between the genotypes for all studied traits. High estimates of genetic gain and broad-sense heritability were observed for the number of pods per plant, the number of pods per main …
Study On The Effect Of Planting Pattern Adjustment On The Growth Of Kiwifruit Inter-Root Microorganisms And Fruit Quality, Haibo Wu, Lianchun Wang, Linan Kang, Chao Liu, Mingwei Li
Study On The Effect Of Planting Pattern Adjustment On The Growth Of Kiwifruit Inter-Root Microorganisms And Fruit Quality, Haibo Wu, Lianchun Wang, Linan Kang, Chao Liu, Mingwei Li
Turkish Journal of Agriculture and Forestry
As the area planted with kiwifruit continues to expand, monoculture continuous cropping is gradually becoming the main mode of its production. However, current kiwifruit soils suffer from nutrient deficiencies and increased toxicity of their own, which are harmful to their yield and quality. The study proposes a kiwifruit-maize intercrop as a starting point for adjusting the cropping pattern. It was then analysed in terms of basic soil physicochemical properties, sucrose enzyme activity, microbial species, and quantity, respectively, and compared with the kiwifruit intercropping method to verify its effect on inter-root microorganisms and fruit quality. The experimental outcomes demonstrated that the …
Sensing Translocating Polymers Via Induced Magnetic Fields, Şahi̇n Büyükdağli
Sensing Translocating Polymers Via Induced Magnetic Fields, Şahi̇n Büyükdağli
Turkish Journal of Physics
The requirement to boost the resolution of nanopore-based biosequencing devices necessitates the integration of novel biosensing techniques with reduced sensitivity to background noise. In this article, we probe the signatures of translocating polymers in magnetic fields induced by ionic currents through membrane nanopores. Within the framework of a previously introduced charge transport theory, we evaluate the magnetic field signals generated by voltage- and pressure-driven DNA translocation events in monovalent salt solutions. Our formalism reveals that in voltage-driven transport, the translocating polymer suppresses the induced magnetic field via the steric blockage of the ion current through the midpore. In the case …
Gold Thin-Film Based Narrow-Band Perfect Absorbers For Near-Ir Frequencies, Serap Aksu
Gold Thin-Film Based Narrow-Band Perfect Absorbers For Near-Ir Frequencies, Serap Aksu
Turkish Journal of Physics
Perfect absorbers have received significant attention due to their tunable and extraordinary absorptive behaviour of light at selected wavelenghts. Such absorption can be achieved by the means of nanostructured materials with various types of flexibility. Despite these advantages nanofabrication is a challenging process. In this study, we manufacture and characterize a gold thin-film based ultra narrow-band perfects absorber that does not require nanostructures for full absorption of the incident light. Perfect absorption is based on Fabry-Perot interference created using a metal-insulator-metal triple layer. The fabrication involves precise deposition of a gold film (35 nm) and silicon nitride dielectric film (110-170 …
Effect Of Lipid-Enriched Diet Associated With Bovine Recombinant Somatotropin On Superovulation Response And Embryo Recovery In Heifers, Richelle Matos Oliveira, Anselmo Domingos Ferreira Santos, Francisco Palma Rennó, Camilla Mendonça Silva
Effect Of Lipid-Enriched Diet Associated With Bovine Recombinant Somatotropin On Superovulation Response And Embryo Recovery In Heifers, Richelle Matos Oliveira, Anselmo Domingos Ferreira Santos, Francisco Palma Rennó, Camilla Mendonça Silva
Turkish Journal of Veterinary & Animal Sciences
The current study aimed to evaluate the effects of soybean oil supplementation associated with the administration of bovine recombinant somatotropin (rBST) on the population of ovarian follicles, standardization of both the superovulation response and embryo recovery in heifers. We used 40 Holstein heifers submitted to a 2 × 2 factorial, forming the experimental groups: DC-SL (control diet plus saline solution application); OL-SL (diet with soybean oil plus saline application); DC-rBST (control diet plus application of 320 mg rBST) and OL-rBST (diet with soybean oil plus the application of 320 mg rBST). The animals received two applications of 500 mg of …
Effect Of Acute And Repeated Noise Exposure On The Behaviour And Lipid Peroxidation In Brain Tissue Of Male And Female Mice, Gabriella Korsós, Kinga Fodor, Annamária Kiss, Anna Blázovics, Sándor György Fekete
Effect Of Acute And Repeated Noise Exposure On The Behaviour And Lipid Peroxidation In Brain Tissue Of Male And Female Mice, Gabriella Korsós, Kinga Fodor, Annamária Kiss, Anna Blázovics, Sándor György Fekete
Turkish Journal of Veterinary & Animal Sciences
Despite the increasingly obvious sex differences, male animals are still predominantly used to study stress and related disorders. The aim of this study was to evaluate the effects of repeated noise stress in female and male mice. In the experiment, 12 male and 12 and female SPF/VAF 6-week-old Crl:CD1(lcr) mice were used. After 5 days of acclimatization all animals were placed in the open-field for three consecutive days where each mouse spent 10 min daily without any noise treatment in order to get used to the circumstances of the test. On day 9 to record baseline behaviour the animals were …
Effects Of Feeding In Different Quality Rangelands On Meat Quality And Fatty Acids Composition In Angora Goat Kids And Young Bucks, Betül Zehra Sariçi̇çek
Effects Of Feeding In Different Quality Rangelands On Meat Quality And Fatty Acids Composition In Angora Goat Kids And Young Bucks, Betül Zehra Sariçi̇çek
Turkish Journal of Veterinary & Animal Sciences
The effects of feeding in different quality rangelands on meat quality and fatty acids composition in Angora goat kids and bucks were determined. Twenty male Angora goat kids were selected from each farm that produces Angora goats in the area. There are three separate rangelands with previously determined quality classes (good, medium, and low-quality). In each farm, among these animals grazed completely on the rangeland, 7 heads from 4-month-old kids and 7 heads from 7-month-old bucks were selected and slaughtered. The Longissimus thoracis muscle was removed for meat quality measurement. The increased rangeland quality increased the protein content of kid's …
Examination Of Canine Herpesvirus-1 In Dogs By Serological, Molecular, And Pathological Methods, Serkan Yildirim, Fatma Gülten Bayraktar, Hakan Aydin, Yavuz Seli̇m Sağlam, Gi̇zem Eser, Muhammet Bahaeddi̇n Dörtbudak
Examination Of Canine Herpesvirus-1 In Dogs By Serological, Molecular, And Pathological Methods, Serkan Yildirim, Fatma Gülten Bayraktar, Hakan Aydin, Yavuz Seli̇m Sağlam, Gi̇zem Eser, Muhammet Bahaeddi̇n Dörtbudak
Turkish Journal of Veterinary & Animal Sciences
In this study, it was aimed to examine Canine Herpesvirus-1 (CHV-1) with different diagnostic methods and investigate the pathological changes in positive samples. For this purpose, 100 dog uteruses of different ages and breeds, were removed by ovariohysterectomy and their blood samples were used as the study material. Enzyme-linked immunosorbent assay (ELISA) and Indirect Fluorescent Antibody Test (IFAT) for serological diagnosis, polymerase chain reaction (PCR) method for molecular diagnosis, immunohistochemistry (IHC) and immunofluorescence (IF) staining for immunopathological diagnosis were performed on the samples. Additionally, hematoxylin and eosin (HE) staining was performed to examine the histopathological changes in the CHV- 1-positive …
Genetic Parameters Of Growth, Reproductive, And Productive Characteristics In Anatolian Buffaloes, Yusuf Kaplan, Mustafa Tekerli̇
Genetic Parameters Of Growth, Reproductive, And Productive Characteristics In Anatolian Buffaloes, Yusuf Kaplan, Mustafa Tekerli̇
Turkish Journal of Veterinary & Animal Sciences
It was aimed to investigate the genetic parameters in growth, fertility, and productivity of Anatolian buffaloes maintained at private farms of Yozgat. A total of 1139 buffalo cows and their calves were used in the study. The weights at birth, weaning, 6th and 12th months of age, and daily live weight gains (DLWG) of buffalo calves born from 2015 to 2019 were recorded. Calving interval (CI) and service period (SP), lactation milk yield (LMY), milk yield per day of lactation period (MYPDLP), milk yield per day of calving interval (MYPDCI), peak yield (PY), a day at peak yield (DPY) and …
Drug Interaction Potential Of Ankaferd Blood Stopper® In Human Hepatocarcinoma Cells, Asli Semi̇z
Drug Interaction Potential Of Ankaferd Blood Stopper® In Human Hepatocarcinoma Cells, Asli Semi̇z
Turkish Journal of Medical Sciences
Background/aim: Ankaferd blood stopper® (ABS) is an herbal extract consisting of mixtures of Alpinia officinarum, Gycyrrhiza glabra, Vitis vinifera, Thymus vulgaris, and Urtica dioica plants and has been used in recent years in Turkish medicine as a hemostatic agent. Despite its extensive usage, there is no information available about the drug interaction in HepG2 cells. The current work evaluated the effect of ABS on the expression of CYP1A1-1A2, CYP2E1, and CYP3A4 isozymes that are primarily involved in drug and carcinogen metabolism. Materials and methods: We selected HepG2 cells as in vitro cellular models of the human liver. The cells were …
The Diagnostic Value Of N-Terminal Probrain Natriuretic Peptides To Differentiate Neonatal Pneumoniae And Transient Tachypnea Of The Newborn, Zeynep Arslan, Serdar Alan, Di̇dem Ali̇efendi̇oğlu
The Diagnostic Value Of N-Terminal Probrain Natriuretic Peptides To Differentiate Neonatal Pneumoniae And Transient Tachypnea Of The Newborn, Zeynep Arslan, Serdar Alan, Di̇dem Ali̇efendi̇oğlu
Turkish Journal of Medical Sciences
Background/aim: The primary objective of the study was to determine the diagnostic value of serum N-terminal probrain natriuretic peptide (NT-proBNP) levels to differentiate neonatal pneumonia (NP) and transient tachypnea of the newborn (TTN). The secondary objective was to investigate the prognostic role of NT-proBNP levels in neonates with severe respiratory distress (RD). Materials and methods: A prospective, observational, single-blinded study involving 58 late preterm and term newborns who were diagnosed with TTN or NP was conducted between June 2020 and June 2021 at a level-3 neonatal intensive care unit in Kırıkkale University Faculty of Medicine. TTN and NP groups were …
The Predictive Significance Of Umbilical Cord Bilirubin And Bilirubin/Albumin Ratio For Neonatal Jaundice In Healthy Term Newborns, Handan Şahan, Selvi̇ Gülaşi, Mustafa Kurthan Mert, Eren Kale Çeki̇nmez
The Predictive Significance Of Umbilical Cord Bilirubin And Bilirubin/Albumin Ratio For Neonatal Jaundice In Healthy Term Newborns, Handan Şahan, Selvi̇ Gülaşi, Mustafa Kurthan Mert, Eren Kale Çeki̇nmez
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is to determine the value of the questions asked in routine follow-up, the cord blood bilirubin (CBB) and bilirubin/albumin (B/A) ratio in estimating the risk of developing hyperbilirubinemia. Materials and methods: Term and healthy 217 newborns whose CBB and albumin could be obtained and whose needed to be measured bilirubin level at the 24th and 72nd hours of life were included. Nutrition, sex and nationality, consanguinity between parents, jaundice in the sibling (s), mother's medications were questioned. CBB and albumin, serum total bilirubin (STB), serum albumin and transcutaneous bilirubin (TcB) at the 24th and …
Outcomes Of Kidney Transplantation In Patients With Congenital Anomalies Of The Kidney And Urinary Tract: A Propensity-Score-Matched Analysis With Case-Control Design, Özgür Akin Oto, Şafak Mi̇ri̇oğlu, Hali̇l Yazici, Ahmet Burak Di̇ri̇m, Nurane Güller, Seda Şafak, Erol Demi̇r, Ayşe Serra Artan, Mesude Yasemi̇n Özlük, Aydin Türkmen, Yaşar Kerem Çalişkan, Krista L. Lentine
Outcomes Of Kidney Transplantation In Patients With Congenital Anomalies Of The Kidney And Urinary Tract: A Propensity-Score-Matched Analysis With Case-Control Design, Özgür Akin Oto, Şafak Mi̇ri̇oğlu, Hali̇l Yazici, Ahmet Burak Di̇ri̇m, Nurane Güller, Seda Şafak, Erol Demi̇r, Ayşe Serra Artan, Mesude Yasemi̇n Özlük, Aydin Türkmen, Yaşar Kerem Çalişkan, Krista L. Lentine
Turkish Journal of Medical Sciences
Background/aim: We compared long-term outcomes after kidney transplantation (KTx) in patients with and without congenital anomalies of the kidney and urinary tract (CAKUT). Materials and methods: KTx recipients (KTRs) with CAKUT in 1980-2016 were identified; their hard copy and electronic medical records were reviewed and compared to a propensity-score-matched control group (non-CAKUT) from the same period. The primary outcomes were graft loss or death with a functioning graft; secondary outcomes included posttransplant urinary tract infections (UTIs) and biopsy-proven rejection (BPR). Results: We identified 169 KTRs with CAKUT and 169 matched controls. Median follow-up was 132 (IQR: 75.0-170.0) months. UTIs were …
Screening Of Antigliadin And Antitissue Transglutaminase Antibodies In Patients With Chronic Plaque Psoriasis: A Case-Control Study, Burhan Engi̇n, Chinara Huseynova, Tümay Ak, Ali̇ Yağiz Ayla, Günay Can, Serdal Uğurlu
Screening Of Antigliadin And Antitissue Transglutaminase Antibodies In Patients With Chronic Plaque Psoriasis: A Case-Control Study, Burhan Engi̇n, Chinara Huseynova, Tümay Ak, Ali̇ Yağiz Ayla, Günay Can, Serdal Uğurlu
Turkish Journal of Medical Sciences
Background/aim: In this study, we aimed to investigate different types of celiac antibodies in psoriasis patients and to see if the presence of the antibodies was associated with other variables. Materials and methods: We included patients with plaque psoriasis who were followed up in our dermatology clinic between February 2019 and February 2021 and added a healthy control group for comparison. The antibodies studied were serum antitissue transglutaminase (tTG)-IgA, tTG-IgG, antigliadin antibody (AGA)-IgA, and AGA-IgG. The patients' records were used to note age, sex, the pattern of psoriasis involvement, psoriasis area and severity index (PASI), presence of hypertension, presence of …
The Effect Of Different Boron Compounds On Nutrient Digestibility, Intestinal Nutrient Transporters, And Liver Lipid Metabolism, Emre Şahi̇n, Cemal Orhan, Füsun Erten, Fi̇kretti̇n Şahi̇n, Nurhan Şahi̇n, Kazi̇m Şahi̇n
The Effect Of Different Boron Compounds On Nutrient Digestibility, Intestinal Nutrient Transporters, And Liver Lipid Metabolism, Emre Şahi̇n, Cemal Orhan, Füsun Erten, Fi̇kretti̇n Şahi̇n, Nurhan Şahi̇n, Kazi̇m Şahi̇n
Turkish Journal of Medical Sciences
Background/aim: Gastrointestinal health is essential for maintaining a healthy lifestyle. Improving nutrient absorption and energy metabolism are the critical targets for intestinal health. This study aimed to determine the effects of different boron (B) derivatives on nutrient digestibility, intestinal nutrient transporters, and lipid metabolism in rats. Materials and methods: Twenty-one rats were allocated to three groups (n = 7) as follows: (i) Control, (ii) Sodium pentaborate pentahydrate (SPP), and (iii) boric acid (BA). The rats were fed a chow diet (AIN-93M) and supplemented with 8 mg/kg elemental B from SPP (45.2 mg/kg BW) and BA (42.7 mg/kg BW) via oral …
T1 Relaxation Time Is Prolonged In Healthy Aging: A Whole Brain Study, Hayri̇ye Aktaş Di̇nçer, Ahmet Muhteşem Ağildere, Di̇dem Gökçay
T1 Relaxation Time Is Prolonged In Healthy Aging: A Whole Brain Study, Hayri̇ye Aktaş Di̇nçer, Ahmet Muhteşem Ağildere, Di̇dem Gökçay
Turkish Journal of Medical Sciences
Background/aim: Measurement of tissue characteristics such as the longitudinal relaxation time (T1) provides complementary information to the volumetric and surface based structural analyses. We aimed to investigate T1 relaxation time characteristics in healthy aging via an exploratory design in the whole brain. The data processing pipeline was designed to minimize errors related to aging effects such as atrophy. Materials and methods: Sixty healthy participants underwent MRI scanning (28 F, 32 M, age range: 18-78, 30 young and 30 old) in November 2017-March 2018 at the Bilkent University UMRAM Center. Four images with varying flip angles with FLASH (fast low angle …
A National, Multicenter, Retrospective Study Evaluating Retention Rate And Efficacy Of Tocilizumab Treatment In Patients With Active Rheumatoid Arthritis Who Had An Inadequate Response To Csdmards And/Or Tnf Inhibitors, Güzi̇de Nevsun İnanç, Mustafa Ender Terzi̇oğlu, Yusuf Karabulut, Zevcet Yilmaz, Emi̇ne Fi̇gen Tarhan, Mehmet Emi̇n Eneci̇k, Ali̇ Şahi̇n, Adem Küçük, Ayşe Ayan, Meti̇n Özgen, Uğur Karasu, Servet Yolbaş
A National, Multicenter, Retrospective Study Evaluating Retention Rate And Efficacy Of Tocilizumab Treatment In Patients With Active Rheumatoid Arthritis Who Had An Inadequate Response To Csdmards And/Or Tnf Inhibitors, Güzi̇de Nevsun İnanç, Mustafa Ender Terzi̇oğlu, Yusuf Karabulut, Zevcet Yilmaz, Emi̇ne Fi̇gen Tarhan, Mehmet Emi̇n Eneci̇k, Ali̇ Şahi̇n, Adem Küçük, Ayşe Ayan, Meti̇n Özgen, Uğur Karasu, Servet Yolbaş
Turkish Journal of Medical Sciences
Background/aim: To describe the disease activity and retention rate in rheumatoid arthritis (RA) patients with inadequate response (IR) to conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) and/or tumor necrosis factor inhibitors (TNFis) who were prescribed tocilizumab (TCZ) as first-line or second-line biologic treatment in real-world setting. Materials and methods: Data gathered from patients' files was used in a multicenter and retrospective context. Retention rates and the Disease Activity Score in 28 joints with CRP (DAS28-CRP) were evaluated at time points. The relationship of drug efficacy with factors such as smoking, obesity, and previous use of TNFis was also examined. Results: One …
The Impact Of Smoking On Response To Tumor Necrosis Factor-Α Inhibitor Treatment In Patients With Ankylosing Spondylitis, Handan Yarkan Tuğsal, Gökçe Kenar Artin, Gerçek Can, Sedat Çapar, Berri̇n Zengi̇n, Servet Akar, Hüseyi̇n Edi̇z Dalkiliç, Abdurrahman Soner Şenel, Süleyman Serdar Koca, Berna Göker, Ayten Yazici, Güzi̇de Nevsun İnanç, Hülya Elli̇dokuz, Nurullah Akkoç, Fatoş Önen
The Impact Of Smoking On Response To Tumor Necrosis Factor-Α Inhibitor Treatment In Patients With Ankylosing Spondylitis, Handan Yarkan Tuğsal, Gökçe Kenar Artin, Gerçek Can, Sedat Çapar, Berri̇n Zengi̇n, Servet Akar, Hüseyi̇n Edi̇z Dalkiliç, Abdurrahman Soner Şenel, Süleyman Serdar Koca, Berna Göker, Ayten Yazici, Güzi̇de Nevsun İnanç, Hülya Elli̇dokuz, Nurullah Akkoç, Fatoş Önen
Turkish Journal of Medical Sciences
Background/aim: To investigate the impact of smoking on disease activity, treatment retention, and response in patients with ankylosing spondylitis (AS) treated with their first tumor necrosis factor-α inhibitor (TNFi). Materials and methods: AS patients who started their first TNFi treatment for the active axial disease (BASDAI ≥ 4) from TURKBIO Registry were included. Treatment response of smoker (current and ex-smokers) and nonsmoker (never smoker) patients were primarily evaluated as achievement of BASDAI50 or improvement in BASDAI at least 20 mm at 3 months and 6 months compared to baseline. Results: There were 322 patients with AS (60% male, 59% smoker, …
Detection And Classification Of White Blood Cells With An Improved Deep Learning-Based Approach, Fatma Akalin, Nejat Yumuşak
Detection And Classification Of White Blood Cells With An Improved Deep Learning-Based Approach, Fatma Akalin, Nejat Yumuşak
Turkish Journal of Electrical Engineering and Computer Sciences
The analysis of white blood cells, which defend the body against deadly infections and disease-causing substances, is an important issue in the medical world. The concentrations of these cells in the blood, examined in 5 classes, i.e. monocytes, eosinophils, basophils, lymphocytes, and neutrophils, vary according to the types of diseases in the body. The peripheral blood smear is widely used to analyze blood cells. Manual evaluation of this method is laborious and time-consuming. At the same time, many environmental and humanistic parameters affect the method's performance. Therefore, in the presented study, a real-time detection process is realized. Firstly, YOLOv5s, YOLOv5x, …
Skin Lesion Segmentation By Using Object Detection Networks, Deeplab3+, And Active Contours, Fatemeh Bagheri, Mohammad Jafar Tarokh, Majid Ziaratban
Skin Lesion Segmentation By Using Object Detection Networks, Deeplab3+, And Active Contours, Fatemeh Bagheri, Mohammad Jafar Tarokh, Majid Ziaratban
Turkish Journal of Electrical Engineering and Computer Sciences
Developing an automatic system for detection, segmentation, and classification of skin lesions is very useful to aid well-timed diagnosis of skin diseases. Lesion segmentation is a crucial task for automated diagnosis of skin cancers, as it affects significantly the accuracy of the subsequent steps. Varieties in sizes and locations of lesions, and the lesions with low-contrast boundaries make this task very challenging. In this paper, a three-stage CNN-based method is presented for accurate segmentation of lesions from dermoscopic images. At the first step, normalization, approximate locations and sizes of lesions are estimated. Due to the importance of the normalization stage, …
Mocmin: Convex Inferring Of Modular Low-Rank Contact Networks Over Covid Diffusion Data, Emre Sefer
Mocmin: Convex Inferring Of Modular Low-Rank Contact Networks Over Covid Diffusion Data, Emre Sefer
Turkish Journal of Electrical Engineering and Computer Sciences
SEIR (which consists of susceptible, exposed, infected, and recovered states) is a common diffusion model which could model different disease propagation dynamics across various domains such as influenza and COVID diffusion. As a motivation, across these domains, observing the node states is relatively easier than observing the network edges over which the diffusion is taking place, or it may not even be possible to observe the underlying network. This paper focuses on the problem of predicting modular low-rank human contact network edges only if a SEIR diffusion dynamics spreading among the human on their contact network can be observed. Such …
Monte-Carlo Method Based Simulations For Photothermal Mucosa Coagulation With Accurate Depth Limits, Merve Türker Burhan, Serhat Tozburun
Monte-Carlo Method Based Simulations For Photothermal Mucosa Coagulation With Accurate Depth Limits, Merve Türker Burhan, Serhat Tozburun
Turkish Journal of Electrical Engineering and Computer Sciences
The mucosa layer, the innermost layer of the gastrointestinal (GI) system, is of great importance in carcinogenesis since most cancerous tissues occur as superficial lesions. Although various treatment strategies exist, the main difficulty in eradicating lesions is unintentional damage to healthy tissues with the uncontrolled depth of treatment. This study proposes a computer modeling approach for simulating depth-resolved photothermal (laser) mucosal coagulation therapy. Computer modeling mimics the thermal dynamics of mucosal tissue to characterize the total heat energy required for successful superficial coagulation, which can be controlled by the scan rate, scan time, output power, and beam diameter of the …
Affective States Classification Performance Of Audio-Visual Stimuli From Eeg Signals With Multiple-Instance Learning, Yaşar Daşdemi̇r, Rüstem Özakar
Affective States Classification Performance Of Audio-Visual Stimuli From Eeg Signals With Multiple-Instance Learning, Yaşar Daşdemi̇r, Rüstem Özakar
Turkish Journal of Electrical Engineering and Computer Sciences
Throughout various disciplines, emotion recognition continues to be an essential subject of study. With the advancement of machine learning methods, accurate emotion recognition from different data modalities (facial images, brain EEG signals) has become possible. Success of EEG-based emotion recognition systems depends on efficient feature extraction and pre/postprocessing of signals. Main objective of this study is to analyze the efficacy of multiple-instance learning (MIL) on postprocessing features of EEG signals using three different domains (time, frequency, time-frequency) for human emotion classification. Methods and results are presented for single-trial classification of valence (V), arousal (A), and dominance (D) ratings from EEG …
Segmentation Of Diatoms Using Edge Detection And Deep Learning, Hüseyi̇n Gündüz, Cüneyd Nadi̇r Solak, Serkan Günal
Segmentation Of Diatoms Using Edge Detection And Deep Learning, Hüseyi̇n Gündüz, Cüneyd Nadi̇r Solak, Serkan Günal
Turkish Journal of Electrical Engineering and Computer Sciences
Diatoms are photosynthesizing algae found in almost every aquatic environment. Detecting the number and diversity of diatoms is very important to analyze water quality appropriately. Accurate segmentation of diatoms is therefore crucial for this detection process. In this study, a new and effective model for the automatic segmentation of diatoms based on image processing and deep learning algorithms is proposed. In the proposed model, edge segments of a given image containing diatoms and nondiatom particles are first obtained. These edge segments are then combined, resulting in closed contours representing diatom candidates. In the final step, the diatom candidates are classified …