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The Importance Of Shape Analysis Of The First Upper Molar In The Separation Of Two Subspecies Of The Hazel Dormouse (Muscardinus Avellanarius (Linnaeus, 1758)) In Northern Anatolia, Güli̇z Yavuz, Hati̇ce Mutlu Eyi̇son, Erkut Kivanç, Engi̇n Selvi̇, Nuri̇ Yi̇ği̇t, Ercüment Çolak Jan 2023

The Importance Of Shape Analysis Of The First Upper Molar In The Separation Of Two Subspecies Of The Hazel Dormouse (Muscardinus Avellanarius (Linnaeus, 1758)) In Northern Anatolia, Güli̇z Yavuz, Hati̇ce Mutlu Eyi̇son, Erkut Kivanç, Engi̇n Selvi̇, Nuri̇ Yi̇ği̇t, Ercüment Çolak

Turkish Journal of Zoology

Morphological features are important for intraspecific and interspecific variation. Teeth are important taxonomical characteristics because they can differ according to diet. Shape analysis of the first upper molar (M1) was used to determine geographical variations and effects of ecological changes on the population structure of Hazel dormice (Muscardinus avellanarius) living in Turkey. Both outline and landmark analysis, as well as a canonical variates analysis, showed significant differences in teeth shape between populations. With this technique, we separated out two subspecies: M. a. trapezius and M. a. abanticus.


Cover And Contents Jan 2023

Cover And Contents

Turkish Journal of Zoology

No abstract provided.


Postmucilage Biodiversity Of Shallow Water Fish Assemblages: A Case Study In The Marmara Sea, Turkey, İsmai̇l Burak Daban, Yusuf Şen, Adnan Ayaz, Uğur Altinağaç, Alkan Özteki̇n, Uğur Özeki̇nci̇, Ali̇ İşmen, Fi̇kret Çakir, Ahsen Yüksek, Teki̇n Demi̇rkiran, Oğuzhan Ayaz, Gençtan Erman Uğur, Bumi̇nhan Burkay Selçuk Jan 2023

Postmucilage Biodiversity Of Shallow Water Fish Assemblages: A Case Study In The Marmara Sea, Turkey, İsmai̇l Burak Daban, Yusuf Şen, Adnan Ayaz, Uğur Altinağaç, Alkan Özteki̇n, Uğur Özeki̇nci̇, Ali̇ İşmen, Fi̇kret Çakir, Ahsen Yüksek, Teki̇n Demi̇rkiran, Oğuzhan Ayaz, Gençtan Erman Uğur, Bumi̇nhan Burkay Selçuk

Turkish Journal of Zoology

A dense mucilage event occurred between November 2020 and August 2021 in the Marmara Sea, Turkey. In this study, the aim was to understand the effect of mucilage on coastal fish biodiversity. For this purpose, juvenile and small-sized adult fish species were sampled with an experimental beach seine at 12 equally-spaced stations around the Marmara Sea between November 2021 and April 2022. In total, 34 species belonging to 19 families were sampled. Approximately 70% of the total fish abundance were Atherina boyeri Risso, 1810, Chelon auratus (Risso, 1810) and Chelon saliens (Risso, 1810). Highest abundance was detected from S5 …


Interactions Between Environmental Factors And The Mesozooplankton Community From The Romanian Black Sea Waters, Elena Bisinicu, George-Emanuel Harcota, Luminita Lazar Jan 2023

Interactions Between Environmental Factors And The Mesozooplankton Community From The Romanian Black Sea Waters, Elena Bisinicu, George-Emanuel Harcota, Luminita Lazar

Turkish Journal of Zoology

The aim of the study was to trace the influence of several abiotic factors on the distribution of the mesozooplankton community from the Black Sea. Sampling was performed in cold and warm seasons of 2013-2020, from stations located on the three sectors of the Romanian Black Sea coast (northern-N, central-C, and southern-S). After determining the species composition, abundance, and biomass, the results were subjected to statistical analysis. A total of 25 taxa were identified, Copepoda representing the bulk of the community. The analysis of the main components explains, through the first two identified factors-temperature and salinity, the variation of environmental …


Length-Weight Relationships And Relative Condition Factors Of Three Coral-Associated Lutjanus Species From Terengganu Waters Of The South China Sea, Malaysia, Md. Moshiur Rahman, Nur Asma Ariffin, Ying Giat Seah, Tun Nurul Aimi Mat Jaafar, Ahasan Habib Jan 2023

Length-Weight Relationships And Relative Condition Factors Of Three Coral-Associated Lutjanus Species From Terengganu Waters Of The South China Sea, Malaysia, Md. Moshiur Rahman, Nur Asma Ariffin, Ying Giat Seah, Tun Nurul Aimi Mat Jaafar, Ahasan Habib

Turkish Journal of Zoology

The present study offers the first report of length-weight relationships (LWRs) and relative condition factor (K$_{n}$) of coralassociated snapper fishes namely: Lutjanus johnii, L. quinquelineatus, and L. xanthopinnis collected from Pulau Kambing fish landing port, Terengganu waters of South China Sea, Malaysia. This study also offers a new maximum total length of 26.8 cm (standard length of 21.3 cm) for L. xanthopinnis. A total of 861 specimens were collected monthly from March 2022 to February 2023 that were caught by using different types of fishing gear such as gill nets (mesh size 45-48 mm), hooks (numbers 9-12), and …


Ecomorphological Patterns And Shape Indices Of Otoliths In The Pagellus Acarne (Actinopterygii, Sparidae) From The Aegean And Marmara Seas, Serdar Yedi̇er, Seda Kontaş Yalçinkaya, Di̇lek Türker, Derya Bostanci Jan 2023

Ecomorphological Patterns And Shape Indices Of Otoliths In The Pagellus Acarne (Actinopterygii, Sparidae) From The Aegean And Marmara Seas, Serdar Yedi̇er, Seda Kontaş Yalçinkaya, Di̇lek Türker, Derya Bostanci

Turkish Journal of Zoology

Pagellus acarne is found in coastal waters worldwide and it includes important species of commercial and recreational fisheries. In this study, 16 morphometric variables of the sagittal otolith, including six morphometric characters, six shape indices, and four ecomorphological indexes, were investigated for the first time among P. acarne stocks collected from the Aegean and Marmara Seas coasts of Turkey. Statistically significant differences were found between the right and left otolith variables of P. acarne individuals in both stocks (p < 0.05). Similarly, significant differences were observed on the same side between stocks (p < 0.05). The right otoliths exhibited higher discrimination power than the left within the two stocks. The PCA showed that only five (31.25%) (otolith area, otolith perimeter, form factor, roundness, and edge complexity index) out of the sixteen variables were quite important characters in the differentiation between stocks. These otolith characters demonstrated a very high rate of accurate discrimination (99.0%) between stocks. The results indicated otolith morphometric characters, shape indices, and ecomorphological indexes can be used as suitable tools to discriminate P. acarne stocks. This is the first study to include all otolith characters such as morphometrics, shape, and ecomorphological indices that …


Discrimination Between Six Commercially Relevant And Ecologically Diverse Fish Species Across The Gulf Of Tunis Using Fatty Acid Composition And Otolith Shape Analyses, Nawzet Bouriga, Wafa Rjiba Bahri, Safa Bejaoui, Madel F. Adjibayo Houeto, Adel A. Basyouny Shahin, Jean-Pierre Quiganrd, Monia Trabelsi, Abderraouf Ben Faleh Jan 2023

Discrimination Between Six Commercially Relevant And Ecologically Diverse Fish Species Across The Gulf Of Tunis Using Fatty Acid Composition And Otolith Shape Analyses, Nawzet Bouriga, Wafa Rjiba Bahri, Safa Bejaoui, Madel F. Adjibayo Houeto, Adel A. Basyouny Shahin, Jean-Pierre Quiganrd, Monia Trabelsi, Abderraouf Ben Faleh

Turkish Journal of Zoology

Fatty acid composition and otolith shape variation of six commercially important fishes, which differ ecologically in their living and feeding habits across the Gulf of Tunis, Tunisia, were analyzed. The aims were to investigate the discrimination and relationship between the six species using both fatty acid composition and otolith shape to examine whether variability in fatty acid composition is consistent with variation in otolith shape and check whether otoliths shape and fatty acids composition have combined characteristic signals for these species. Tukey's test with one-way ANOVA indicated significant differences in total percentages of saturated (SFAs), polyunsaturated (PUFAs), and monounsaturated (MUFAs) …


Discovering Underground Bat Hibernacula In Lowland Eastern Europe, Lena Godlevska, Aliaksei Shpak, Mariia Savchenko, Pavlo Vorobei Jan 2023

Discovering Underground Bat Hibernacula In Lowland Eastern Europe, Lena Godlevska, Aliaksei Shpak, Mariia Savchenko, Pavlo Vorobei

Turkish Journal of Zoology

The importance of underground hibernacula for the conservation of bats and monitoring their populations is well-recognized. However, the lowland territory of Belarus, with absent natural caves and suitable for bats mines, was one of the least surveyed European regions in terms of underground bat sites, and especially hibernacula. To address this knowledge gap, in 2020, we conducted a broadscale one winter bat survey, exploring 90 underground sites (basements, cellars, church crypts, fortifications, and facilities of abandoned Soviet missile bases) in various parts of Belarus. To our knowledge, none of these sites had been examined for bats before. In 56 of …


Diversity And Prevalence Of Ornithophilic Louse Flies (Diptera: Hippoboscidae: Ornithomyinae) In Serbia, Tibor Rekecki, Drazenko Rajkovic Jan 2023

Diversity And Prevalence Of Ornithophilic Louse Flies (Diptera: Hippoboscidae: Ornithomyinae) In Serbia, Tibor Rekecki, Drazenko Rajkovic

Turkish Journal of Zoology

Ectoparasites are diverse organisms that exploit animal hosts using various strategies. One such group represents the louse flies (Hippoboscidae) from the subfamily Ornithomyinae, which are permanent, highly specialised, hematophagous ectoparasites of poultry and wild birds found worldwide. The main objective of this research is to examine the mean abundance, prevalence, and diversity of ornithophilic louse flies in Serbia. They have been detected through visual inspection or fumigation of caught birds. In total, 79 louse flies belonging to four genera and six species were collected from 62 individuals within 26 host species. A single louse fly infested the bulk of captured …


Novel Results On Trapezoid-Type Inequalities For Conformable Fractional Integrals, Fati̇h Hezenci̇, Hüseyi̇n Budak Jan 2023

Novel Results On Trapezoid-Type Inequalities For Conformable Fractional Integrals, Fati̇h Hezenci̇, Hüseyi̇n Budak

Turkish Journal of Mathematics

This paper establishes an identity for the case of differentiable $s-$convex functions with respect to the conformable fractional integrals. By using this identity, sundry trapezoid-type inequalities are proven by $s-$convex functions with the help of the conformable fractional integrals. Several important inequalities are acquired with taking advantage of the convexity, the Hölder inequality, and the power mean inequality. Moreover, an example using graph is given in order to show that our main results are correct. By using the special choices of the obtained results, we present several new results connected with trapezoid-type inequalities.


Investigation Of Relationships Between Serum Lactate, Acute Phase Proteins, Pro/ Antiinflammatory Cytokine Levels, And Metritis Formation In Holstein Dairy Heifers, Talha Avcilar, Davut Koca, Yavuz Nak, Mustafa Eren Şahi̇n, Musa Özgür Özyi̇ği̇t, Deni̇z Nak Jan 2023

Investigation Of Relationships Between Serum Lactate, Acute Phase Proteins, Pro/ Antiinflammatory Cytokine Levels, And Metritis Formation In Holstein Dairy Heifers, Talha Avcilar, Davut Koca, Yavuz Nak, Mustafa Eren Şahi̇n, Musa Özgür Özyi̇ği̇t, Deni̇z Nak

Turkish Journal of Veterinary & Animal Sciences

The main purpose of this investigation was to identify and suggest suitable early screening inflammatory markers for the early diagnosis of uterine infections such as acute septic metritis (ASM) in the Holstein heifers. In addition, to achieve the above -mentioned aim, the objectives of the present study were tried to determine the relationship between blood serum lactate, acute phase proteins (APPs), pro/anti inflammatory cytokine levels, and metritis formation in Holstein heifers. For this purpose, 250 Holstein heifers which were 11-13 months old, were chosen as the study material. After heifers were conceived, blood serum samples were collected at the 8th …


Effect Of Different Light Intensities And Colors On Growth Performance And Reproductive Characteristics In Japanese Quails, Fawwad Ahmad, Muhammad Sharif, Muhammad Ashraf, Muhammad Riaz, Muhammad Shoaib, Talha Siddique, Aqian Ahmed, Ahmad Hamad Sheir, Muhammad Ahsan Yaseen, Muhammad Mahboob Ali Hamid Jan 2023

Effect Of Different Light Intensities And Colors On Growth Performance And Reproductive Characteristics In Japanese Quails, Fawwad Ahmad, Muhammad Sharif, Muhammad Ashraf, Muhammad Riaz, Muhammad Shoaib, Talha Siddique, Aqian Ahmed, Ahmad Hamad Sheir, Muhammad Ahsan Yaseen, Muhammad Mahboob Ali Hamid

Turkish Journal of Veterinary & Animal Sciences

Light is one of the most important environmental factors in quail farming, as it has a significant impact on production efficiency and reproductive characteristics. The purpose of this study was to determine the effect of different light intensities and colors on production performance in Japanese quails. For the first experiment, 200 Japanese quails were divided into five treatment groups, each with four replicates (10 birds in each). The birds in the control treatment were exposed to a light intensity of 20 lux, while the other four treatment groups were exposed to light intensities of 10 lux, 15 lux, 25 lux, …


Arterial Vascularization Of The Spleen In Merino Sheep, Melek Tosun, Şükrü Hakan Atalgin Jan 2023

Arterial Vascularization Of The Spleen In Merino Sheep, Melek Tosun, Şükrü Hakan Atalgin

Turkish Journal of Veterinary & Animal Sciences

In this study, it is aimed to reach detailed information about the anatomy of arteries in the sheep spleen, which can be used as an example and model for the success of planned or emergency surgical interventions related to the spleen. In spleen injuries, the spleen may be divided into two or three parts, or it may be limited to cracks on the spleen. In particular, it is aimed to protect the organs that have been damaged by trauma recently. Operations such as splenectomy and splenography are surgical procedures that require good knowledge of the pathways of artery and its …


Modeling Of Individual Egg Weights Of Lohmann-Brown Layer Hens, Esra Yavuz, Samet Hasan Abaci, Kadi̇r Erensoy, Mustafa Şahi̇n Jan 2023

Modeling Of Individual Egg Weights Of Lohmann-Brown Layer Hens, Esra Yavuz, Samet Hasan Abaci, Kadi̇r Erensoy, Mustafa Şahi̇n

Turkish Journal of Veterinary & Animal Sciences

This study was carried out to determine the most suitable model for egg weights of the Cubic, Gompertz, Logistics, Gamma, Richard, Piecewise Quadratic, Orscov, and Sigmoaidal models, which are widely used in estimation. Lohmann-Brown Classic laying hens raised in Ondokuz Mayıs University Research and Application farm were used as animal material. In the modeling of egg weights of 351 layer hens raised in 3-storey cages, individual egg weight data measured at weekly intervals, 32 on the 1st floor, 17 on the 2nd floor, and 27 on the 3rd floor, were taken into account, and a total of 76 hens' individual …


The Effect Of Simvastatin Treatment On Tnf-Alpha-Induced Inflammation In Human Vascular Endothelial Cells (Huvecs), Büşra Görgün, Betül İşi̇ner Kaya, Kübra Kaya, Leyla Di̇dem Kozaci Jan 2023

The Effect Of Simvastatin Treatment On Tnf-Alpha-Induced Inflammation In Human Vascular Endothelial Cells (Huvecs), Büşra Görgün, Betül İşi̇ner Kaya, Kübra Kaya, Leyla Di̇dem Kozaci

Turkish Journal of Veterinary & Animal Sciences

This study investigates the effects of simvastatin (SMV) on human umbilical vein endothelial cells (HUVECs) inflamed by tumor necrosis factor-alpha (TNF-a). Cells were treated with simvastatin (5 μM, 10 μM, and 50 μM) with/without TNF (20 ng/mL). The effects of simvastatin on the proliferation of cells were examined, and its cytotoxic effect was determined by lactate dehydrogenase (LDH) assays. Metalloproteinase expression (MMP-2 and MMP-9) levels of SMV at different concentrations were determined by qPCR, and protein levels were determined by Western blot. The increasing concentrations of SMV down-regulated the expression levels of MMPs. After stimulation with TNF-a, the effect of …


The First Record Of Philophthalmus Lucipetus (Trematoda: Philophthalmidae) In The Great Egret (Ardea Alba) From Turkey, Mehmet Öztürk, Şi̇nasi̇ Umur Jan 2023

The First Record Of Philophthalmus Lucipetus (Trematoda: Philophthalmidae) In The Great Egret (Ardea Alba) From Turkey, Mehmet Öztürk, Şi̇nasi̇ Umur

Turkish Journal of Veterinary & Animal Sciences

The genus Philophthalmus, Looss 1899 (Echinostoma: Philophthalmidae) is a cosmopolitan group of parasites that infects the eyes of birds and mammals, including humans. A great egret (Ardea alba) was found dead in Kızılırmak Delta, Samsun, Turkey. The bird was transported to the Faculty of Veterinary Medicine, Ondokuz Mayıs University, Samsun Turkey, for a necropsy. In the parasitological examination, a trematode was detected in the eye, and then it was identified as Philophthalmus lucipetus. This is the first report of the zoonotic parasite P. lucipetus in Turkey.


Investigation Of The In Vitro Antioxidant Activity Of Fermented Tomato Pruning Residues And Its Effects On Biochemical And Hematological Parameters Of Rats, Bariş Denk, Beyza Aydoğan, İsmai̇l Bayram, Abdurrahman Fati̇h Fi̇dan Jan 2023

Investigation Of The In Vitro Antioxidant Activity Of Fermented Tomato Pruning Residues And Its Effects On Biochemical And Hematological Parameters Of Rats, Bariş Denk, Beyza Aydoğan, İsmai̇l Bayram, Abdurrahman Fati̇h Fi̇dan

Turkish Journal of Veterinary & Animal Sciences

In the tomato greenhouse production process, a by-product emerges in the form of greenhouse residues. One of these residues is leaf pruning residue, which poses an environmental pollution problem in terms of waste management. The purpose of this work was to investigate the use of fermented tomato leaves (FTL) as an animal feed additive and its potential to mitigate the environmental pollution problem caused by greenhouse pruning residues. The pruning residues were fermented and their in vitro antioxidant activity (AOA) levels were analyzed using 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 2,2-diphenyl-1-picryl-hydrazylhydrate (DPPH), reducing power (RP), and total phenolic content (TPC) assays. Wistar albino …


Investigation Of Bmp15 And Gdf9 Gene Polymorphisms And Their Effects On Litter Size In Anatolian Sheep Breed Akkaraman, Koray Kirikçi Jan 2023

Investigation Of Bmp15 And Gdf9 Gene Polymorphisms And Their Effects On Litter Size In Anatolian Sheep Breed Akkaraman, Koray Kirikçi

Turkish Journal of Veterinary & Animal Sciences

This study aimed to examine the polymorphism of the BMP15 (FecX$^{G}$ and FecX$^{I}$) and GDF9 (G1 and G4) genes and the association between genotypes and litter size in the Akkaraman breed. Blood samples were taken from 100 ewes in total. Genomic DNA was obtained from whole blood. The PCR-RFLP technique was employed to determine the polymorphisms of the genes under investigation. The G1 was the only polymorphic among the four loci analyzed. The frequencies for the GA and GG genotypes were 0.26 and 0.74, respectively, while the A and G allele frequencies were 0.13 and 0.87, respectively. The observed and …


Investigation Of Snps In Bmp15 And Gdf9 Genes In "Çepni" And "Of" Sheep In The Black Sea Region Of Turkey, Koray Kirikçi Jan 2023

Investigation Of Snps In Bmp15 And Gdf9 Genes In "Çepni" And "Of" Sheep In The Black Sea Region Of Turkey, Koray Kirikçi

Turkish Journal of Veterinary & Animal Sciences

Sheep fertility genes have been studied in Turkey for many years. But so far it cannot be said that a satisfactory result has been achieved in terms of the number of detected polymorphisms on fertility genes. Exhibiting the genetic structure of local gene resources adapted to a particular region is very important for sustainability, conservation and breeding studies, and many other issues such as profitability. Therefore, the primary aim of this study was to investigate the single nucleotide polymorphisms (SNPs) on the BMP15 and GDF9 genes in two new Turkish sheep breeds, Çepni and Of. DNA sequencing was performed to …


Influence Of Lactobacillus Plantarum Administration On Some Serum/Tissue (Uterus) Antioxidant And Cytokine Levels In Female Rats Exposed To Cadmium (Cd), İhsan Kisadere, Bariş Güner, Hakan Tavşanli, Mehmet Faruk Aydin, Mustafa Usta Jan 2023

Influence Of Lactobacillus Plantarum Administration On Some Serum/Tissue (Uterus) Antioxidant And Cytokine Levels In Female Rats Exposed To Cadmium (Cd), İhsan Kisadere, Bariş Güner, Hakan Tavşanli, Mehmet Faruk Aydin, Mustafa Usta

Turkish Journal of Veterinary & Animal Sciences

The study aimed to investigate the effects of oral Lactobacillus plantarum (Lp) administration on some serum/tissue (uterus) antioxidant and cytokine levels as well as histopathologic changes in female rats exposed chronically to Cd. For this purpose, rats were separated into four groups including control (C, n = 8), cadmium (Cd, n = 8), Lp (n = 8), and Cd + Lp (n = 8). Cd (dissolved in water at a dose of 2.04 mg/mL) was orally administered to Cd and Cd + Lp groups for 28 days. Besides, active-live Lp, which was grown at a level of approximately 10$^{8}$-10$^{9}$ cfu/mL …


Could There Be A Relationship Between Feeding Characteristics And The Shape Of Condylus Occipitalis And Foramen Magnum In Mammals?, Yasi̇n Demi̇raslan, İsmai̇l Demi̇rci̇oğlu, İftar Gürbüz, Funda Aksünger Karaavci, Abdullah Ortadeveci, Özcan Özgel Jan 2023

Could There Be A Relationship Between Feeding Characteristics And The Shape Of Condylus Occipitalis And Foramen Magnum In Mammals?, Yasi̇n Demi̇raslan, İsmai̇l Demi̇rci̇oğlu, İftar Gürbüz, Funda Aksünger Karaavci, Abdullah Ortadeveci, Özcan Özgel

Turkish Journal of Veterinary & Animal Sciences

The aim of the study was to investigate the shape of the foramen magnum and condylus occipitalis of mammalian species belonging to different feeding groups. For this, two-dimensional geometric morphometric method analyses were applied. The data from the skulls of the 12 species were used. In principal component analysis, the first three principal components accounted for 70.353%of the total shape variation. According to the first principal component, the dorsal edge of the condylus occipitalis and foramen magnum contributed the most to shape variation. Most of the individuals were correctly separated according to the feeding groups. The most accurate grouping features …


The Protective Impact Of Growth Hormone Against Rotenone-Induced Apoptotic Cell Death Via Acting On Endoplasmic Reticulum Stress And Autophagy Axis, Özge Rencüzoğullari, Selay Tornaci, Yağmur Çeli̇k, Nayat Narot Taş, Pinar Obakan Yerli̇kaya, Eli̇f Damla Arisan, Ajda Çoker Gürkan Jan 2023

The Protective Impact Of Growth Hormone Against Rotenone-Induced Apoptotic Cell Death Via Acting On Endoplasmic Reticulum Stress And Autophagy Axis, Özge Rencüzoğullari, Selay Tornaci, Yağmur Çeli̇k, Nayat Narot Taş, Pinar Obakan Yerli̇kaya, Eli̇f Damla Arisan, Ajda Çoker Gürkan

Turkish Journal of Biology

Human growth hormone (GH) is crucial modulator of cellular metabolisms, including cell proliferation and organ development, by stimulating insulin-like growth factor-1 (IGF-1), which has various functions such as cell proliferation, tissue growth, survival, or neuroprotection. Therefore, GH is implicated as a critical player in the cell and can enhance neurogenesis and provide neuroprotection during the treatment of neurological diseases such as Parkinson's disease (PD). In this study, the neuroprotective role of GH was investigated in rotenone-induced PD models for the first time. Both SH-SY5Y and SK-N-AS neuroblastoma cells were exposed to rotenone to mimic PD pathogenesis as stated in previous …


Functional Enhancement Of Acute Infracted Heart By Coinjection Of Autologous Adipose-Derived Stem Cells With Matrigel, Baozhu Wang, Mengmeng Wang, Yan Li, Meihua Shao, Dan Zhan, Shiqi Yan, Xiang Ma, Yitong Ma Jan 2023

Functional Enhancement Of Acute Infracted Heart By Coinjection Of Autologous Adipose-Derived Stem Cells With Matrigel, Baozhu Wang, Mengmeng Wang, Yan Li, Meihua Shao, Dan Zhan, Shiqi Yan, Xiang Ma, Yitong Ma

Turkish Journal of Biology

Recent clinical developments in tissue bioengineering have applications in acute cardiac ischemia and infarction and include the use of stem cells that combine injectable scaffold material. This study aimed to evaluate the effects of adipose-derived stem cells (ADSCs) that combine the Matrigel scaffold on cardiac morphology/functions. The autologous ADSCs myocardial infarction (MI) model was induced by the permanent ligation method of the left anterior descending coronary artery (LAD). MI-operated rats were randomly divided into PBS group, Matrigel group, PBS plus ADSCs group (PBS+ADSCs), and Matrigel plus ADSCs group (Matrigel+ADSCs). Matrigel was used as an injectable scaffold. Rats with a 1-week-old …


Tsrna-15797-Modified Bmsc-Derived Exosomes Mediate Lfng To Induce Angiogenesis In Osteonecrosis Of The Femoral Head, Shanhong Fang, Mengqiang You, Jie Wei, Peng Chen Jan 2023

Tsrna-15797-Modified Bmsc-Derived Exosomes Mediate Lfng To Induce Angiogenesis In Osteonecrosis Of The Femoral Head, Shanhong Fang, Mengqiang You, Jie Wei, Peng Chen

Turkish Journal of Biology

Background: Osteonecrosis of the femoral head (ONFH) is an ischemic disease characterized by the impairment of angiogenesis. We have previously elucidated the role of tsRNAs and BMSC exosomes in ONFH, but whether tsRNA-modified BMSC exosomes promote angiogenesis in ONFH remains unclear. Methods: The expression of angiogenesis-related tsRNA in plasma exosomes from ONFH patients was examined by q-PCR. The function of tsRNA in HUVECs was identified by CCK-8 and angiogenesis assay. Exosomes purified from tsRNA-15797 overexpressed BMSCs were cocultured with HUVECs to examine their role in angiogenesis. The molecule mechanism of tsRNA-15797-modified exosomes was explored by RNA sequencing, dual-luciferase assay, and …


Mir-216b-5p Promotes Late Apoptosis/Necroptosis In Trastuzumab-Resistant Sk-Br-3 Cells, İştar Burcu Dolapçi, Senem Noyan, Ayşegül Yücel Polat, Hakan Gürdal, Bala Gür Dedeoğlu Jan 2023

Mir-216b-5p Promotes Late Apoptosis/Necroptosis In Trastuzumab-Resistant Sk-Br-3 Cells, İştar Burcu Dolapçi, Senem Noyan, Ayşegül Yücel Polat, Hakan Gürdal, Bala Gür Dedeoğlu

Turkish Journal of Biology

Breast cancer is the most common cancer in women. The human epidermal growth factor receptor 2 (HER2) overexpressing subtype is related to poor prognosis with an aggressive phenotype and is reported as one of the most commonly seen subtypes. Trastuzumab is prevalently used as a treatment method for HER2+ breast cancer however, resistance to the drug frequently occurs following the treatment. MicroRNAs (miRNAs) are 19-23 nucleotide long small RNAs, which regulate gene expression at posttranscriptional level and studies show that there are differentially expressed miRNAs between drug sensitive and resistant groups, indicating that they might have some key roles in …


Effect Of Okra Bast Fillers On Biodegradation Properties Of Poly(Vinyl Alcohol) Composites, Gazi Md Arifuzzaman Khan, Nazi̇re Deni̇z Yilmaz Jan 2023

Effect Of Okra Bast Fillers On Biodegradation Properties Of Poly(Vinyl Alcohol) Composites, Gazi Md Arifuzzaman Khan, Nazi̇re Deni̇z Yilmaz

Turkish Journal of Chemistry

This paper focuses on the effect of okra bast fillers on biodegradation of poly(vinyl alcohol) composites. Fibers were obtained from okra plant stems via biological degumming and subjected to different chemical treatments such as scouring, alkalizing, maleic anhydride treatment, and vinyl acetate grafting. The fibers were ground and PVA-okra bast filler composites were produced at 20 wt% fiber load via the solution casting method. The obtained composites were tested in terms of mechanical properties and exposed to biodegradation in soil. Effects of okra bast filler addition and chemical treatments on changes in mass, breaking strength, elasticity modulus, and breaking elongation …


Investigating The Effect Of Poly (Ε-Caprolactone) Nanofibers Scaffolds With Random, Unidirectionally, And Radially Aligned Morphologies On The Fibroblast Cell?S Attachment And Growth Behavior, Saeed Nezari, Mohammadamin Sarli, Ahmad Hivechi, Hajir Bahrami, Peiman B. Milan, Noorahmad Latifi, Fatemeh Latifi, Tayyeb Ghadimi, S. Mohammad Amin Haramshahi, Soheila Naderi Gharahgheshlagh Jan 2023

Investigating The Effect Of Poly (Ε-Caprolactone) Nanofibers Scaffolds With Random, Unidirectionally, And Radially Aligned Morphologies On The Fibroblast Cell?S Attachment And Growth Behavior, Saeed Nezari, Mohammadamin Sarli, Ahmad Hivechi, Hajir Bahrami, Peiman B. Milan, Noorahmad Latifi, Fatemeh Latifi, Tayyeb Ghadimi, S. Mohammad Amin Haramshahi, Soheila Naderi Gharahgheshlagh

Turkish Journal of Chemistry

In the last decade, significant progress in tissue engineering, repairing, and replacing organs has been achieved. The design and production of scaffolds for tissue engineering are one of the main areas which have attracted the researcher's interest. In this regard, electrospinning is one of the most popular methods of nanoscale scaffold similar to extracellular matrix production. This paper reports the fabrication of scaffolds consisting of radially aligned PCL nanofibers by utilizing a collector composed of a central point electrode and a peripheral ring electrode. The chemical and physical properties were compared using SEM, FTIR, XRD, and DSC experiments, as well …


Evaluation Of Photochemically Cross-Linked Collagen/Gold Nanoparticle Composites As Potential Skin Tissue Scaffolds, Evri̇m Meri̇ç Yelkuvan, Özge Erdemli̇, Bengi̇ Yilmaz, Ömer Aktürk Jan 2023

Evaluation Of Photochemically Cross-Linked Collagen/Gold Nanoparticle Composites As Potential Skin Tissue Scaffolds, Evri̇m Meri̇ç Yelkuvan, Özge Erdemli̇, Bengi̇ Yilmaz, Ömer Aktürk

Turkish Journal of Chemistry

Collagen type I is the main structural unit in skin tissue and is therefore used preferentially in skin tissue scaffolds. However, collagen-based 3D scaffolds have weak aqueous stability and degradation profiles in their uncross-linked states and chemical cross-linking reagents arise toxicity concerns, which generally restrict the spectrum of their biomedical applicability. Here, the research goal is to photochemically cross-link collagen type I with rose bengal (RB) when subjected to green laser light and to investigate the effect of silk sericin-capped gold nanoparticles (S-AuNP) when incorporated into scaffolds on the cross-linking process and thus on the scaffold properties. All the collagen …


Structure-Emission Relationship Of Some Coumarin Laser Dyes And Related Molecules: Prediction Of Radiative Energy Dissipation And The Intersystem Crossing Rate Constants, Msa Abdelmottaleb Jan 2023

Structure-Emission Relationship Of Some Coumarin Laser Dyes And Related Molecules: Prediction Of Radiative Energy Dissipation And The Intersystem Crossing Rate Constants, Msa Abdelmottaleb

Turkish Journal of Chemistry

Dye lasers are commonly used in optical investigation because their solutions in organic solvents deliver tunable, coherent emissions. They exhibit intense fluorescence owing to some specific spectroscopic characteristics. One drawback of the laser dyes is that it shows excessive triplet-state losses (TSLs.) The lack of theoretical predictions of fluorescence rates, intersystem crossing (ISC), and phosphorescence in laser dyes prompted us to report on the predicted rates of radiative and nonradiative transitions of some laser dyes. Structural engineering by some substituents influencing the simulated rates of coumarin laser dye derivatives for an efficient operation was investigated. The NH$_{2}$ functional group renders …


Synthesis And Kinetic Analysis Of Poly(N-Acryloylmorpholine) Brushes Via Surface Initiated Raft Polymerization, Esma Mutlutürk, Tuncer Çaykara Jan 2023

Synthesis And Kinetic Analysis Of Poly(N-Acryloylmorpholine) Brushes Via Surface Initiated Raft Polymerization, Esma Mutlutürk, Tuncer Çaykara

Turkish Journal of Chemistry

Polymer brushes are promising many applications as smart materials and biocompatible surfaces. Surface-initiated reversible addition-fragmentation chain transfer (RAFT) polymerization is one of the most effective techniques for synthesis of well-defined polymer brushes. Herein, a biocompatible, uniform and stable poly(N-acryloylmorpholine)-silicon hybrid system was achieved using surface-initiated RAFT polymerization. Evidence of a well-controlled surface-initiated RAFT polymerization was confirmed by a linear increase of number average molecular weight (M$_{n}$) with overall monomer conversions. Water contact angle, ellipsometry, X-ray photoelectron spectroscopy and atomic force microscopy verified the presence of poly(N-acryloylmorpholine) (poly(NAM)) on silicon wafers. The grafting density (σ) and the average distance between grafting …