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Articles 481 - 510 of 1022
Full-Text Articles in Entire DC Network
The Effect Of Staphylococcus Aureus Extracellular Products (Secp) On Performance,Selective Innate Immune Indexes, And Humoral Immune Response Against Avian Influenzaand Newcastle Disease Vaccines In Broiler Chickens, Teimour Tabari, Younes Papi, Esmaeil Azizi, Forough Talazadeh, Ramezan Ali Jafari, Masoud Ghorbanpoor
The Effect Of Staphylococcus Aureus Extracellular Products (Secp) On Performance,Selective Innate Immune Indexes, And Humoral Immune Response Against Avian Influenzaand Newcastle Disease Vaccines In Broiler Chickens, Teimour Tabari, Younes Papi, Esmaeil Azizi, Forough Talazadeh, Ramezan Ali Jafari, Masoud Ghorbanpoor
Turkish Journal of Veterinary & Animal Sciences
Improving the immune response is important for many reasons such as vaccine failure, immunosuppressive diseases, and antibiotics misuse. Research on materials likely to have immune-enhancing effects has been on the rise. Factors, substances, or compounds that can regulate different functions of the immune system can be used to enhance specific and even nonspecific responses to vaccines. Different amounts (0, 25, 50, and 100 μg) of Staphylococcus aureus extracellular products (SECP) were injected subcutaneously to different groups of chickens during the first vaccination against avian influenza (AI) and Newcastle disease (ND) viruses to investigate the effect of SECP on innate and …
Update On Liver Transplantation-Newer Aspects, Rahşan Olga Meti̇n, Cem Şi̇mşek, Ahmet Ömür Gürakar
Update On Liver Transplantation-Newer Aspects, Rahşan Olga Meti̇n, Cem Şi̇mşek, Ahmet Ömür Gürakar
Turkish Journal of Medical Sciences
Liver transplantation (LT) remains the only therapeutic option offering gold standard treatment for end-stage liver disease (ESLD) and acute liver failure (ALF), as well as for certain early-stage liver tumors. Currently, the greatest challenge facing LT is the simple fact that there are not enough adequate livers for all the potential patients that could benefit from LT. Despite efforts to expand the donor pool to include living and deceased donors, organ shortage is still a major problem in many countries. To solve this problem, the use of marginal liver grafts has become an inevitable choice. Although the definition of marginal …
Thiol-Disulfide Homeostasis: An Integrated Approach With Biochemical And Clinical Aspects, Özcan Erel, Serpi̇l Erdoğan
Thiol-Disulfide Homeostasis: An Integrated Approach With Biochemical And Clinical Aspects, Özcan Erel, Serpi̇l Erdoğan
Turkish Journal of Medical Sciences
Dynamic thiol-disulfide homeostasis (TDH) is a new area has begun to attract more scrutiny. Dynamic TDH is reversal of thiol oxidation in proteins and represents the status of thiols (-SH) and disulfides (-S-S-). Organic compounds containing the sulfhydryl group is called thiol, composed of sulfur and hydrogen atoms. Disulfides are the most important class of dynamic, redox responsive covalent bonds build in between two thiol groups. For many years, thiol levels were analyzed by several methods. During last years, measurements of disulfide levels have been analyzed by a novel automated method, developed by Erel and Neselioglu. In this method, addition …
A Novel Molecular Imprinting Polymer For The Selective Adsorptionof D-Arabinitol From Spiked Urine, Yuni Retnaningtyas, Ganden Supriyanto, Ni Nyoman Tri Puspaningsih, Roedi Irawan, Siswandono Siswodihardjo
A Novel Molecular Imprinting Polymer For The Selective Adsorptionof D-Arabinitol From Spiked Urine, Yuni Retnaningtyas, Ganden Supriyanto, Ni Nyoman Tri Puspaningsih, Roedi Irawan, Siswandono Siswodihardjo
Turkish Journal of Chemistry
In this research, molecular imprinting polymers (MIPs) for D-arabinitol were synthesized using a bulk polymerization method through a noncovalent approach. The MIPs were prepared by using D-arabinitol as a template, acrylamide as a functional monomer, ethylene glycol dimethacrylateas cross-linker, benzoyl peroxide as an initiator and dimethyl sulfoxideas a porogen. MIPS was synthesized in several formulas with a different molar ratio of template to functional monomers and cross-linker. Fourier-transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM) were used to characterize the MIPs produced. A batch rebinding assay was used to test the binding efficiency of each formula. Batch rebinding test …
Computational And Biological Studies Of Novel Thiazolyl Coumarin Derivatives Synthesized Through Suzuki Coupling, Shaista Parveen, Saima Kalsoom, Rifhat Bibi, Ambreen Asghar, Abdul Hameed, Waqar Ahmed, Abbas Hassan
Computational And Biological Studies Of Novel Thiazolyl Coumarin Derivatives Synthesized Through Suzuki Coupling, Shaista Parveen, Saima Kalsoom, Rifhat Bibi, Ambreen Asghar, Abdul Hameed, Waqar Ahmed, Abbas Hassan
Turkish Journal of Chemistry
The current investigation presents the synthesis, computational molecular-docking and biological activity studies of arylated thiazole coumarins. Aryl substituted thiazolyl coumarin derivatives were synthesized via Suzuki cross-coupling reaction. A detailed reaction condition optimization revealed that the Pd-PEPPSI-IPent precatalyst in only 2 mol% loading resulted in the desired product with high yield. The aim of this study was to examine the antimicrobial behavior of thiazole coumarin derivatives through in vitro and in silico studies. All the compounds showed activity against both antibacterial strains, Staphylococcus aureus and Escherichia coli, except 5d. Similarly, the compounds 5a, 5b, and 5d were found to be active …
Combined Computational And Experimental Studies On Cysteine-Sulfadiazine Adduct Formation, Nursel Açar Selçuki̇, Emi̇ne Coşkun, Ender Bi̇çer
Combined Computational And Experimental Studies On Cysteine-Sulfadiazine Adduct Formation, Nursel Açar Selçuki̇, Emi̇ne Coşkun, Ender Bi̇çer
Turkish Journal of Chemistry
The electrochemical characterization of sulfadiazine-cysteine (SD-CYS) adduct formation was performed in phosphatebuffer(pH7)onthebasisofvoltammetriccurrentandpeakpotentialmeasurements. Duetotheassociationof cysteine with sulfadiazine, the reduction peak currents of mercuric and mercurous cysteine thiolates decreased and their peak potentials simultaneously shifted to less negative potentials. By using the current changes of mercurous cysteine thiolate, it was determined that cysteine and sulfadiazine are associated with a 1:1 stoichiometry with a conditional association constant of 1.99 ×10$^{4}$ M$^{-1}$. In addition to experimental studies, a computational approach was carried out to study the geometrical parameters, electron densities, and UV-Vis absorption spectra of sulfadiazine and SDCYS adduct in water. Calculated (B3LYP/6-311++G(d,p) level) …
Fabrication And Biocompatibility Assessment Of Polypyrrole/Cobalt(Ii) Metal-Organic Frameworks Nanocomposite, Mehrnaz Mehrabani, Zeinab Ansari Asl, Farzaneh Rostamzadeh, Saeideh Jafarinejad Farsangi, Mahnaz Sadat Hashemi, Mozhgan Sheikholeslami, Zeinab Neisi
Fabrication And Biocompatibility Assessment Of Polypyrrole/Cobalt(Ii) Metal-Organic Frameworks Nanocomposite, Mehrnaz Mehrabani, Zeinab Ansari Asl, Farzaneh Rostamzadeh, Saeideh Jafarinejad Farsangi, Mahnaz Sadat Hashemi, Mozhgan Sheikholeslami, Zeinab Neisi
Turkish Journal of Chemistry
Nowadays, metal-organic frameworks (MOFs) have emerged as promising tools for different biological applications and therefore, efforts are ongoing to develop more biocompatible MOFs-based nanocomposites. We aimed to fabricate some new conductive nanocomposites of polypyrrole and cobalt-MOF with different weight percentages (PPy/x%Co-MOF)usingthesolutionmixingmethodandcharacterizethemthroughFT-IR(Fourier-transforminfrared), PXRD (powder X-ray diffraction), SEM (scanning electron microscope), and TEM (transmission electron microscope) techniques. The biocompatibility of nanocomposites was assessed by haemolytic, cytotoxic, and quantitative reverse transcription PCR (qRT-PCR) assays. FT-IR and PXRD results revealed that nanocomposites consisted of pure MOFs and PPy. Moreover, SEM results indicated their spherical morphology along with an average diameter of 190 nm. (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium …
Bioreduction: The Biological Activity, Characterization, And Synthesis Of Silver Nanoparticles, Nesri̇n Korkmaz
Bioreduction: The Biological Activity, Characterization, And Synthesis Of Silver Nanoparticles, Nesri̇n Korkmaz
Turkish Journal of Chemistry
Today, nanoparticles are effectively used in different areas. Initially, physical and chemical methods were used in the synthesis of nanoparticles. Biosynthesis (green synthesis) has emerged as an alternative to overcome the toxic effects of chemically synthesized nanoparticles. In this study, green synthesis of silver nanoparticles (AgNPs) with the leaf extract of Anthurium andraeanum was performed. UV-Vis spectrophotometry, scanning transmission electron microscopy, and XRD were applied to characterize the biosynthesized nanoparticles. As a result of the characterization, the spectra showed that a spectrum at a wavelength of about 419 nm and a spherical size of 38 nm nanoparticles was formed. Antibacterial …
Effect Of Polyelectrolyte Complex Formation On The Antibacterial Activity Of Copolymer Of Alkylated 4-Vinylpyridine, Murat Topuzoğullari
Effect Of Polyelectrolyte Complex Formation On The Antibacterial Activity Of Copolymer Of Alkylated 4-Vinylpyridine, Murat Topuzoğullari
Turkish Journal of Chemistry
Polymers bearing quaternized 4-vinylpyridine (QVP) groups are known for their antibacterial activities and these polymers can form polyelectrolyte complexes (PEC) with polyanions through electrostatic interactions. PEC formation can be used to adjust the antibacterial activity of polymers of QVP, deliver active molecules, or design antibacterial supramolecular structures. However, the antibacterial activity of PECs of QVP polymers has not been investigated. In this study, a copolymer of QVP was mixed with polyacrylic acid in various molar ratios of components to form PECs. Hydrodynamic diameters and zeta potentials of formed PECs were determined by dynamic and electrophoretic light scattering spectroscopy techniques. The …
Bis Benzothiophene Schiff Bases: Synthesis And In Silico-Guided Biological Activity Studies, Yasemi̇n Ünver, Di̇lek Ünlüer, Şahi̇n Di̇rekel, Serdar Durdaği
Bis Benzothiophene Schiff Bases: Synthesis And In Silico-Guided Biological Activity Studies, Yasemi̇n Ünver, Di̇lek Ünlüer, Şahi̇n Di̇rekel, Serdar Durdaği
Turkish Journal of Chemistry
Since benzo [$b$] thiophene scaffold is one of the privileged structures in drug discovery as this core exhibitsactivities for different biological problems, in this study bis (benzo[$b$]thiophene-2-yl) alkyl methanimine derivatives (1-9) were synthesized by reacting benzo[$b$]thiophene-2-carbaldehyde with diamines. All newly compounds were characterized by IR, $^{1}$H NMR and $^{13}$C NMR spectroscopic methods. Synthesized compounds were investigated using binary QSAR-based models on therapeutic activity prediction of synthesized compounds and they showed high predicted activities in following diseases: bacterial, angina, allergy, depression and obesity. Thus, they were then tested for their antimicrobial and antileishmanial activities as a result of this theoretical study. …
Ovarian Stimulation Induces High Expression Of Interleukin-1ss And Disrupts The Histological Features Of The Fallopian Tube, Mahmoud Moussa, Sameh Mohamed Farouk
Ovarian Stimulation Induces High Expression Of Interleukin-1ss And Disrupts The Histological Features Of The Fallopian Tube, Mahmoud Moussa, Sameh Mohamed Farouk
Turkish Journal of Veterinary & Animal Sciences
The objective of this study was to investigate whether there is an association between ovarian stimulation and interrupted gamete interaction in the rat fallopian tube in vivo. We evaluated the protein expression of interleukin-1ß (IL-1ß) via immunohistochemistry and assessed the key histological features of the ovaries, fallopian tubes, and uteri of the rats following treatment with mild (15 IU) and high (30 IU) doses of gonadotropins compared to an unstimulated control group. The serum concentration of estradiol was also determined by immunoassay. The results revealed that high levels of circulating estrogen were associated with higher expression of the IL-1ß protein …
Evaluation Of Milk Glutathione Peroxidase And Superoxide Dismutase Levels In Subclinical Mastitis In Damascus Goats, İsfendi̇yar Darbaz, Seçki̇n Salar, Serkan Sayiner, İdi̇l Baştan, Osman Ergene, Ayhan Baştan
Evaluation Of Milk Glutathione Peroxidase And Superoxide Dismutase Levels In Subclinical Mastitis In Damascus Goats, İsfendi̇yar Darbaz, Seçki̇n Salar, Serkan Sayiner, İdi̇l Baştan, Osman Ergene, Ayhan Baştan
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was to evaluate milk glutathione peroxidase (GPx) and superoxide dismutase (SOD) levels in Damascus goats with subclinical mastitis. According to the somatic cell counts (SCCs), 193 Damascus goats included in the study were divided into healthy (n = 75; SCC 0.05). In summary, a significant increase in GPx and decrease in SOD levels, respectively, were determined in goat milk samples with subclinical mastitis, and these changing trends were correlated with milk SCCs. However, age, parity, and number of offspring were not associated with these changing patterns.
Genetic Analysis Of Iranian Mycoplasma Gallisepticum Isolates Using Gene-Targeted Sequencing Of Complete Pvpa Gene, Naghmeh Kabiri, Mohsen Bashashati, Mehdi Vasfi Marandi, Mansour Banani, Fereshteh Sabouri
Genetic Analysis Of Iranian Mycoplasma Gallisepticum Isolates Using Gene-Targeted Sequencing Of Complete Pvpa Gene, Naghmeh Kabiri, Mohsen Bashashati, Mehdi Vasfi Marandi, Mansour Banani, Fereshteh Sabouri
Turkish Journal of Veterinary & Animal Sciences
This study aims to evaluate Mycoplasma gallisepticum (MG) genetic diversity through the complete sequencing of the pvpA gene among six MG isolates present in industrial poultry from 2015 to 2016. The genetic comparison of these six isolates showed similarities of over 94% and 92% in terms of nucleotide and amino acid sequences, respectively. The size of the PvpA protein in the studied isolates included three different sizes with 361, 364, and 366 amino acids. The carboxy-terminus of the studied PvpA proteins contained 11 tetrapeptides of P-R-P-M/Q/N motifs with truncation in the proline-rich region. Based on the BLAST analysis, the pvpA …
Isolation And Molecular Characterization Of Salmonella Enterica And Escherichia Coli From Poultry Samples, Ayli̇n Cesur, Saci̇de Özlem Ulutaş, Yeşi̇m Soyer
Isolation And Molecular Characterization Of Salmonella Enterica And Escherichia Coli From Poultry Samples, Ayli̇n Cesur, Saci̇de Özlem Ulutaş, Yeşi̇m Soyer
Turkish Journal of Veterinary & Animal Sciences
Innumerable foodborne pathogens including Salmonella and Escherichia coli pose a serious threat to human health and food safety. As perishable foods, poultry products are considered one of the most common sources of foodborne pathogens including Salmonella and E. coli due to transmission of drug resistance, dissemination of organisms, and cross-contamination. In our study, phenotypic and genotypic characterizations of Salmonella enterica and E. coli isolated from packaged raw chicken products were carried out. Samples belonging to different commercial brands were collected in Ankara in 2015. Among 15 out of 19 Salmonella enterica subsp. enterica strains isolated from different and/or same poultry …
A Class Of Finite Difference Schemes For Singularly Perturbed Delay Differential Equations Of Second Order, Pramod Chakravarthy Podila, Kamalesh Kumar
A Class Of Finite Difference Schemes For Singularly Perturbed Delay Differential Equations Of Second Order, Pramod Chakravarthy Podila, Kamalesh Kumar
Turkish Journal of Mathematics
In this paper, we proposed a new class of finite difference schemes for solving singularly perturbed delay differential equation of second order. The proposed schemes are oscillation-free and more accurate than conventional schemes on a uniform mesh. These schemes are easily adaptable on special meshes like Shishkin mesh or Bakhvalov mesh and are uniformly convergent with respect to the perturbation parameter. The error analysis has been carried out and numerical examples are presented to show the accuracy and efficiency of the proposed schemes.
Between-Host Hiv Model: Stability Analysis And Solution Using Memeticcomputing, Musharif Ahmed, Ijaz Mansoor Qureshi, Muhammad Aamer Saleem, Muhammad Zubair, Saad Zafar
Between-Host Hiv Model: Stability Analysis And Solution Using Memeticcomputing, Musharif Ahmed, Ijaz Mansoor Qureshi, Muhammad Aamer Saleem, Muhammad Zubair, Saad Zafar
Turkish Journal of Electrical Engineering and Computer Sciences
HIV poses a great threat to humanity for two major reasons. First it attacks the immunity system of the body and second, it is epidemic in nature. Mathematical models of HIV have been instrumental in understanding and controlling the infection. In this paper, we solve the between host epidemic model of HIV, described by nonlinear coupled differential equations, by using memetic computing. Under this model, the sexually active population is divided into four classes and we investigate the transfer of individuals from one class to another. The solution consists of Bernstein polynomials whose parameters have been optimized by using differential …
Exploiting Stochastic Petri Nets With Fuzzy Parameters To Predict Efficient Drug Combinations For Spinal Muscular Atrophy, Rza Bashi̇rov, Recep Duranay, Adi̇l Şeytanoğlu, Mani Mehraei, Ni̇met Akçay
Exploiting Stochastic Petri Nets With Fuzzy Parameters To Predict Efficient Drug Combinations For Spinal Muscular Atrophy, Rza Bashi̇rov, Recep Duranay, Adi̇l Şeytanoğlu, Mani Mehraei, Ni̇met Akçay
Turkish Journal of Electrical Engineering and Computer Sciences
Randomness and uncertainty are two major problems one faces while modeling nonlinear dynamics of molecular systems. Stochastic and fuzzy methods are used to cope with these problems, but there is no consensus among researchers regarding which method should be used when. This is because the areas of applications of these methods are overlapping with differences in opinions. In the present work, we demonstrate how to use stochastic Petri nets with fuzzy parameters to manage random timing of biomolecular events and deal with the uncertainty of reaction rates in biological networks. The approach is demonstrated through a case study of simulation-based …
Performance Evaluation Of Webrtc-Based Online Consultation Platform, Ergün Alperay Tarim, Hüseyi̇n Cumhur Teki̇n
Performance Evaluation Of Webrtc-Based Online Consultation Platform, Ergün Alperay Tarim, Hüseyi̇n Cumhur Teki̇n
Turkish Journal of Electrical Engineering and Computer Sciences
Information technologies give patients the opportunity to communicate with medical professionals remotely. Telemedicine uses these technologies to provide advanced healthcare and medical services. We present a medical online consultation application based on Web Real-Time Communications (WebRTC) technology enabling chat, audio, and video calls. Communication architecture and protocols of the application are explained in detail. Additionally, the user interface of the application is shown via performed calls. The application is tested and evaluated on different network connections (3G, 4G, local, and DSL) and different browsers and mobile operating systems (Android, Chrome, Firefox, Internet Explorer, iOS, Opera, Safari). During calls, communication quality …
8-Hydroxy-2'-Deoxyguanosine As A Biomarker Of Oxidative Stress In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease, Xing Liu, Kaili Deng, Sixia Chen, Yunshi Zhang, Jing Yao, Xiaoqin Weng, Yang Zhang, Tianming Gao, Ganzhu Feng
8-Hydroxy-2'-Deoxyguanosine As A Biomarker Of Oxidative Stress In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease, Xing Liu, Kaili Deng, Sixia Chen, Yunshi Zhang, Jing Yao, Xiaoqin Weng, Yang Zhang, Tianming Gao, Ganzhu Feng
Turkish Journal of Medical Sciences
8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a biomarker of oxidative stress and has been implicated in many diseases. The aim of this study was to investigate the clinical value of plasma 8-OHdG level in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Materials and methods: A total of 154 subjects were enrolled in this study, including 20 healthy volunteers, 24 COPD patients in the stable phase, and 110 AECOPD patients. Peripheral blood samples, demographic information, and clinical characteristics were collected from all subjects at the time of being recruited into the study. Plasma 8-OHdG level was detected by enzyme-linked immunosorbent assay.Results: 8-OHdG …
Evaluation Of Measles Immunity In Turkey: Is It Still A Threat?, Selda Karaayvaz, Melahat Melek Oğuz, Ufuk Beyazova, Fatma Gülay Korukluoğlu, Yasemi̇n Coşgun, Zeli̇ha Güzelküçük, Fatma Nur Baran Aksakal, Fi̇gen Şahi̇n Dağli
Evaluation Of Measles Immunity In Turkey: Is It Still A Threat?, Selda Karaayvaz, Melahat Melek Oğuz, Ufuk Beyazova, Fatma Gülay Korukluoğlu, Yasemi̇n Coşgun, Zeli̇ha Güzelküçük, Fatma Nur Baran Aksakal, Fi̇gen Şahi̇n Dağli
Turkish Journal of Medical Sciences
Background/aim: Measles is one of the important vaccine-preventable diseases with many complications in childhood. This study presents cross-sectional seroepidemiological data, beginning from neonatal cord blood in infants to children under 6 years of age, about waning of measles antibody and tries to suggest the proper time for measles immunization.Materials and methods: A total of 564 blood samples consisting of neonatal cord blood and samples taken from infants and children at ages of 6, 9, 24-48, and 49-72 months were analyzed for measles seropositivity in a period of 6 months. Results: Measles seropositivity rate was 72.5% in 109 cord blood samples, …
Neutrophil To Lymphocyte Ratio As A Predictor Of Treatment Response And Mortality In Septic Shock Patients In The Intensive Care Unit, Rabi̇a Sari, Zühal Karakurt, Mustafa Ay, Muhammed Emi̇n Çeli̇k, Ülgen Yalaz Tekan, Fulya Çi̇yi̇ltepe, Feyza Kargin, Cüneyt Saltürk, Özlem Yazicioğlu Moçi̇n, Gökay Güngör, Nalan Adigüzel
Neutrophil To Lymphocyte Ratio As A Predictor Of Treatment Response And Mortality In Septic Shock Patients In The Intensive Care Unit, Rabi̇a Sari, Zühal Karakurt, Mustafa Ay, Muhammed Emi̇n Çeli̇k, Ülgen Yalaz Tekan, Fulya Çi̇yi̇ltepe, Feyza Kargin, Cüneyt Saltürk, Özlem Yazicioğlu Moçi̇n, Gökay Güngör, Nalan Adigüzel
Turkish Journal of Medical Sciences
Background/aim: While C-reactive protein (CRP) is a well-studied marker for predicting treatment response and mortality in sepsis, it was aimed to assess the efficacy of the neutrophil lymphocyte ratio (NLR) as a predictor of mortality and treatment response in sepsis patients in the intensive care unit (ICU). Materials and methods: In this retrospective cross-sectional study, sepsis patients were divided according to the presence of septic shock on the 1st day of ICU stay, and then subgrouped according to mortality. Patient demographics, acute physiologic and chronic health evaluation II and sequential organ failure assessment scores, NLR and CRP (on the 1st, …
Serum Prolidase Level In Patients With Brucellosis And Its Possible Relationship With Pathogenesis Of The Disease: A Prospective Observational Study, Oğuzhan Sitki Di̇zdar, Ayşe Turunç Özdemi̇r, Osman Başpinar, Derya Koçer, Yavuz Katircilar, İlhami̇ Çeli̇k
Serum Prolidase Level In Patients With Brucellosis And Its Possible Relationship With Pathogenesis Of The Disease: A Prospective Observational Study, Oğuzhan Sitki Di̇zdar, Ayşe Turunç Özdemi̇r, Osman Başpinar, Derya Koçer, Yavuz Katircilar, İlhami̇ Çeli̇k
Turkish Journal of Medical Sciences
Background/aim: Changes in collagen metabolism and fibroblastic activity may play a role in the pathogenesis of brucellosis. The prolidase enzyme plays an important role in collagen synthesis. We aimed to investigate the association of prolidase levels with brucellosis.Materials and methods: Serum prolidase levels in 20 patients newly diagnosed with brucellosis were compared with levels in 30 healthy control subjects. Patients with brucellosis were reassessed 3 months later for prolidase, other laboratory measurements, and response to treatment. Results: The levels of serum prolidase were significantly higher in brucellosis patients compared with those of healthy controls. Prolidase, sedimentation, and C-reactive protein levels …
Fabp4 Levels In Hypothyroidism And Its Relationship With Subclinical Atherosclerosis, Mürşi̇de Tan, Hakan Korkmaz, Hüseyi̇n Aydin, Duygu Kumbul Doğuç
Fabp4 Levels In Hypothyroidism And Its Relationship With Subclinical Atherosclerosis, Mürşi̇de Tan, Hakan Korkmaz, Hüseyi̇n Aydin, Duygu Kumbul Doğuç
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is to evaluate the relationship between serum fatty acid binding protein 4 (FABP4) levels and carotid intima media thickness (CIMT) in patients with hypothyroidism.Materials and methods: Forty subclinical hypothyroidism patients, 40 overt hypothyroidism patients, and 40 healthy controls were enrolled in the study. Blood pressure, body mass index, CIMT, fasting blood sugar, creatine, alanine aminotransferase, lipid parameters, insulin, free thyroxine, triiodothyronine, thyroid-stimulating hormone (TSH), thyroid peroxidase antibody (anti-TPO), thyroglobulin antibody (anti-TG), high-sensitivity C-reactive protein (Hs-CRP), and FABP4 levels of all participants were measured.Results: Serum FABP4 levels were significantly higher in patients with subclinical and …
Effects Of Different Zinc Levels On Grain Yield And Some Phenological Characteristics Of Red Lentil (Lens Culinaris Medic.) Under Arid Conditions, Ayşe Gülgün Öktem
Effects Of Different Zinc Levels On Grain Yield And Some Phenological Characteristics Of Red Lentil (Lens Culinaris Medic.) Under Arid Conditions, Ayşe Gülgün Öktem
Turkish Journal of Agriculture and Forestry
This research aimed to determine the effects of different zinc (Zn) levels on the grain yield and some phenological characteristics of the Fırat-87 red lentil variety (Lens culinaris Medic.). The study was conducted during the winter months of 2013-2014 and 2014- 2015 in Zn-deficit areas of Şanlıurfa, Turkey. The experimental design was a randomized complete block design with 4 replicates. The Fırat-87 lentil variety and Zn sulfate (ZnSO4.7H2O) were used as the plant material and Zn source, respectively. The Zn levels used were the control (0 kg ha-1 Zn), 5 kg ha-1 Zn, 10 kg ha-1 Zn, 15 kg ha-1 …
Viral Prevalence, Clinical Profiles And Comparison Of Severity Scores For Predicting The Mortality Of Adults With Severe Acute Respiratory Infections, Hakan Aydin, Hali̇l Doğan, Doğaç Ni̇yazi̇ Özüçeli̇k, Mehmet Koçak, Osman Avşar Gül
Viral Prevalence, Clinical Profiles And Comparison Of Severity Scores For Predicting The Mortality Of Adults With Severe Acute Respiratory Infections, Hakan Aydin, Hali̇l Doğan, Doğaç Ni̇yazi̇ Özüçeli̇k, Mehmet Koçak, Osman Avşar Gül
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the accuracy of severity scores for predicting the 28-day mortality among adults with severe acute respiratory infection (SARI) admitted to the emergency department.Materials andmethods: This study included 159 consecutive adult patients with SARI admitted to the emergency department of a tertiary hospital. A standard form was filled out in order to record demographic information, clinical parameters, laboratory tests, and radiographic findings of the patients. CURB-65, PSI, SIRS, qSOFA, SOFA and APACHE II scores were compared between the survivor and nonsurvivor groups. Results: Of 159 patients included in the study, 38.4% were …
Comparative Evaluation Of Liver, Spleen, And Kidney Stiffness In Hiv-Monoinfected Pediatric Patients Via Shear Wave Elastography, Emi̇ne Çalişkan, Gürkan Atay, Manolya Kara, Murat Sütçü, Zuhal Bayramoğlu, Selda Hançerli̇ Törün, Ayper Somer, İbrahi̇m Adaletli̇
Comparative Evaluation Of Liver, Spleen, And Kidney Stiffness In Hiv-Monoinfected Pediatric Patients Via Shear Wave Elastography, Emi̇ne Çalişkan, Gürkan Atay, Manolya Kara, Murat Sütçü, Zuhal Bayramoğlu, Selda Hançerli̇ Törün, Ayper Somer, İbrahi̇m Adaletli̇
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the stiffness of the liver, spleen, and kidneys in HIV-monoinfected children via shear wave elastography (SWE).Materials and methods: Twenty-one HIV-monoinfected children and 37 healthy subjects were included in this study. Livers, spleens, and kidneys of the participants were examined via ultrasound and SWE. Patients were divided into two groups according to the presence of pathologic ultrasonographic findings. Routine laboratory tests were also recorded. Stiffness of these organs was compared between patients and control groups.Results: Liver transaminases, blood urea, and creatinine levels were normal in all subjects. Ultrasonographic examination revealed hepatosplenomegaly (n = 1, 4.7%), …
Determination Of Liver Fibrosis Stages In Egyptian Chronic Hepatitis B Patients By A Noninvasive Tool, Waleed Serag, Magdy Mahmoud, Basem Eysa, Sara Mahmoud
Determination Of Liver Fibrosis Stages In Egyptian Chronic Hepatitis B Patients By A Noninvasive Tool, Waleed Serag, Magdy Mahmoud, Basem Eysa, Sara Mahmoud
Turkish Journal of Medical Sciences
Background/aim: Hepatitis B virus (HBV) infection is the leading cause of liver fibrosis (LF). The prognosis and management of patients with chronic hepatitis B virus depend on the amount and progression of liver fibrosis. Angiopoietin-like protein 2 (Angptl2) is not only a chronic inflammatory mediator, but also a tissue-remodeling factor. The aim of this study is to explore the predictive value of Angptl2 in different fibrosis stages in patients chronically infected with HBV. Materials and methods: Eighty patients with chronic HBV infection undergoing Fibroscan were included. Serum concentrations of Angptl2 were detected using a commercial ELISA kit.Results: Angptl2 levels were …
Bloodstream Infections In Pediatric Hematology/Oncology Patients: Six Years? Experience Of A Single Center In Turkey, Tuğçe Tural Kara, Tuğba Erat, Aysun Yahşi̇, Hali̇l Özdemi̇r, Di̇lber Tali̇a İleri̇, Eli̇f İnce, Nurdan Taçyildiz, Emel Ünal, Ergi̇n Çi̇ftci̇, Erdal İnce
Bloodstream Infections In Pediatric Hematology/Oncology Patients: Six Years? Experience Of A Single Center In Turkey, Tuğçe Tural Kara, Tuğba Erat, Aysun Yahşi̇, Hali̇l Özdemi̇r, Di̇lber Tali̇a İleri̇, Eli̇f İnce, Nurdan Taçyildiz, Emel Ünal, Ergi̇n Çi̇ftci̇, Erdal İnce
Turkish Journal of Medical Sciences
Background/aim: Bloodstream infections are the major cause of morbidity, increased cost, prolonged hospitalization, and mortality in pediatric patients. Identifying the predominant microorganisms and antimicrobial susceptibilities in centers helps to select effective empirical antimicrobials which leads to positive clinical outcomes. We aimed to identify the causative microorganisms and their antimicrobial susceptibilities in patients with bloodstream infections.Materials and methods: Data belonging to patients with hematological and/or oncological diseases admitted to our hospital with fever between January 2010 and November 2015 were analyzed. Results: In total, 71 patients who had 111 bloodstream infection episodes were included. Responsible pathogens were detected as follows: 35.1% …
Risk Factors For Bacteremia In Children With Febrile Neutropenia, Soner Sertan Kara, Hasan Tezer, Meltem Polat, Burcu Ceylan Cura Yayla, Tuğba Bedi̇r Demi̇rdağ, Arzu Okur, Ali̇ Fettah, Sali̇ha Kanik Yüksek, Anil Tapisiz, Zuhre Kaya, Namik Özbek, İdi̇l Yeni̇cesu, Hüsni̇ye Neşe Yarali, Ülker Koçak
Risk Factors For Bacteremia In Children With Febrile Neutropenia, Soner Sertan Kara, Hasan Tezer, Meltem Polat, Burcu Ceylan Cura Yayla, Tuğba Bedi̇r Demi̇rdağ, Arzu Okur, Ali̇ Fettah, Sali̇ha Kanik Yüksek, Anil Tapisiz, Zuhre Kaya, Namik Özbek, İdi̇l Yeni̇cesu, Hüsni̇ye Neşe Yarali, Ülker Koçak
Turkish Journal of Medical Sciences
Background/aim: Bacteremia remains an important cause of morbidity and mortality during febrile neutropenia (FN) episodes. We aimed to define the risk factors for bacteremia in febrile neutropenic children with hemato-oncological malignancies. Materials and methods: The records of 150 patients aged ?18 years who developed FN in hematology and oncology clinics were retrospectively evaluated. Patients with bacteremia were compared to patients with negative blood cultures.Results: The mean age of the patients was 7.5 ± 4.8 years. Leukemia was more prevalent than solid tumors (61.3% vs. 38.7%). Bacteremia was present in 23.3% of the patients. Coagulase-negative staphylococci were the most frequently isolated …
Identification Of Streptomyces Strains Isolated From Humulus Lupulus Rhizosphere And Determination Of Plant Growth Promotion Potential Of Selected Strains, Fadi̇me Özdemi̇r Koçak
Identification Of Streptomyces Strains Isolated From Humulus Lupulus Rhizosphere And Determination Of Plant Growth Promotion Potential Of Selected Strains, Fadi̇me Özdemi̇r Koçak
Turkish Journal of Biology
In the present study it was aimed to obtain novel strains of actinomycetes that have the ability to promote plant growth. For this, seven soil samples from the rhizosphere of Humulus lupulus (Pazaryeri, Bilecik) were used and potential isolates were obtained. 16S rRNA genes of 30 isolates were amplified by PCR and sequenced. Eighteen isolates were found to be closely related to Streptomycetes spp. and they were tested for their proteolytic activity, cellulase activity, phosphate solubility, IAA production, biofilm formation, and growth in nitrogen-limited medium. Two isolates, HCI 12 and HCI 36, were selected according to the results of these …