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Effectiveness Of Bitter Melon Extract In The Treatment Of Ischemic Wounds In Rats, Öznur Gürlek Kisacik, Ülkü Güneş, Mustafa Volkan Yaprakci, Korhan Altunbaş
Effectiveness Of Bitter Melon Extract In The Treatment Of Ischemic Wounds In Rats, Öznur Gürlek Kisacik, Ülkü Güneş, Mustafa Volkan Yaprakci, Korhan Altunbaş
Turkish Journal of Biology
There is no consensus on the properties of an ideal dressing for treating wounds. The aim of this study was to investigate the efficacy of dressings using topically administered bitter melon extract with olive oil, pure olive oil, nitrofurazone, and saline in the healing of ischemic wounds. A sample group of 48 rats was used in the trial. Their wounds were treated with bitter melon extract, pure olive oil, nitrofurazone, and saline. Data were collected between October 2014 and April 2015. The highest percentage (94.7%) of wound healing was observed in the bitter melon extract group and the lowest percentage …
Decellularization Of Rat Adipose Tissue, Diaphragm, And Heart: A Comparison Of Two Decellularization Methods, Meli̇s Sesli̇, Esi̇n Akbay, Mehmet Ali̇ Onur
Decellularization Of Rat Adipose Tissue, Diaphragm, And Heart: A Comparison Of Two Decellularization Methods, Meli̇s Sesli̇, Esi̇n Akbay, Mehmet Ali̇ Onur
Turkish Journal of Biology
Decellularization is a process that involves the removal of cellular material from the tissues and organs while maintaining the structural, functional, and mechanical properties of extracellular matrix. The purpose of this study was to carry out decellularization of rat adipose tissue, diaphragm, and heart by using two different methods in order to compare their efficiency and investigate proliferation profiles of rat adipose-tissue-derived mesenchymal stem cells (AdMSCs) on these scaffolds. Tissues were treated with an optimized detergent-based decellularization (Method A) and a freeze-and-thaw-based decellularization (Method B). AdMSCs were then seeded on scaffolds having a density of 2 × 105 cells/scaffold and …
A Comparative Study Of Fuzzy Linear Regression And Multiple Linear Regression Inagricultural Studies: A Case Study Of Lentil Yield Management, Karim Sorkheh, Ahmad Kazemifard, Shakiba Rajabpoor
A Comparative Study Of Fuzzy Linear Regression And Multiple Linear Regression Inagricultural Studies: A Case Study Of Lentil Yield Management, Karim Sorkheh, Ahmad Kazemifard, Shakiba Rajabpoor
Turkish Journal of Agriculture and Forestry
This study investigates the advantages of two fuzzy linear regression (FLR) models, namely the Tanaka and the Savic and Pedrycz models, over multiple linear regression (MLR) for lentil yield management. We used a fuzzy approach to model the yield of lentil genotypes in which the input is crisp and the output fuzzy. Moreover, after finding FLR equations, we estimated the output corresponding to the collection of fuzzy inputs by using fuzzy algebraic operations and an appropriate defuzzification method known as the center of area method. Results showed the superiority of the Tanaka model over MLR because of reducing the included …
Effects Of Hot Water And Uv-C On Mineral Content Changes In Two Strawberry Cultivarsstored At Different Temperatures, Şeyda Çavuşoğlu
Effects Of Hot Water And Uv-C On Mineral Content Changes In Two Strawberry Cultivarsstored At Different Temperatures, Şeyda Çavuşoğlu
Turkish Journal of Agriculture and Forestry
In this study, two standard strawberry cultivars, Rubygem and Sabrina, were treated with UV-C (254 nm), hot water (60° C for 10 s), and UV-C + hot water after harvesting and stored in modified atmosphere packaging (MAP) at 0 °C and 5 °C. The variations in mineral contents including phosphorus (P), potassium (K), calcium (Ca), magnesium (Mg), copper (Cu), manganese (Mn), sodium (Na), and zinc (Zn) were analyzed during storage periods. Analysis of variance for storage temperature, storage time, cultivar, and treatments showed that storing both cultivars at different temperatures followed by all treatments caused some increases in P and …
Occurrence, Damage, And Population Dynamics Of The Olive Fruit Fly(Bactrocera Oleae Gmelin) In The Turkish Republic Of Northern Cyprus, Murat Helvaci, Mehmet Aktaş, Özge Özden
Occurrence, Damage, And Population Dynamics Of The Olive Fruit Fly(Bactrocera Oleae Gmelin) In The Turkish Republic Of Northern Cyprus, Murat Helvaci, Mehmet Aktaş, Özge Özden
Turkish Journal of Agriculture and Forestry
The olive is one of the most important crops of the Mediterranean region. Ninety-eight percent of the world?s olive production occurs in this region. However, pest control is a major concern of olive growers, and the olive fruit fly is one of the major economic pests. The aim of this research was to observe their population, infestation rates, and effect on the quality of olive oil. This research included 14 olive groves within 2 different locations. To determine the population dynamics of adult olive fruit flies, 6 yellow sticky traps were placed haphazardly within the tree canopies (approximately 1.5 m …
Determination Of Soil Nutrient Status In Vuralia Turcica Populations Growing At Different Locations In The Central Anatolia Region Of Turkey, Di̇lek Tekdal, Burçi̇n Çingay, Mehmet Seli̇m Çeti̇ner
Determination Of Soil Nutrient Status In Vuralia Turcica Populations Growing At Different Locations In The Central Anatolia Region Of Turkey, Di̇lek Tekdal, Burçi̇n Çingay, Mehmet Seli̇m Çeti̇ner
Turkish Journal of Botany
This study is an overview of the importance of soil nutrients for the maintenance of Vuralia turcica, which is an endemic in Turkey due to its natural habitats. Electrical conductivity, pH, and mineral element content (macroelements: nitrogen, phosphorus, potassium, calcium, magnesium, and sodium, and microelements: boron, cadmium, copper, iron, manganese, nickel, lead, and zinc) were analyzed in 21 soil samples taken at 30?60 m depth at 21 points from 8 different locations where V. turcica was growing to determine nutrient content, which is important for soil fertility and controls the crop yield. According to pH analysis, all samples were strongly …
Bioinformatics Prediction And Annotation Of Cherry (Prunus Avium L.) Micrornas And Their Targeted Proteins, Iftekhar Ahmed Baloch, Muhammad Younas Khan Barozai, Muhammad Din
Bioinformatics Prediction And Annotation Of Cherry (Prunus Avium L.) Micrornas And Their Targeted Proteins, Iftekhar Ahmed Baloch, Muhammad Younas Khan Barozai, Muhammad Din
Turkish Journal of Botany
MicroRNAs (miRNAs) are important noncoding regulatory RNAs. They are expressed endogenously and are 18-26 nucleotides in length. These small molecules are conserved evolutionarily within the same kingdom and their conserved nature becomes an important logical tool for the quest of conserved miRNAs in other species by homology search using bioinformatics tools. Cherry (Prunus avium L.) is one of the important and nutritious species of the family Rosaceae, mainly distributed in temperate climate. This research is an attempt to identify and characterize conserved miRNAs in cherry from express sequence tags (ESTs). Bioinformatics analysis of cherry ESTs resulted in the identification of …
Diversity And Functional Traits Of Spontaneous Plant Species In Algerian Rangelands Rehabilitated With Prickly Pear (Opuntia Ficus-Indica L.) Plantations, Souad Neffar, Taha Menasria, Haroun Chenchouni
Diversity And Functional Traits Of Spontaneous Plant Species In Algerian Rangelands Rehabilitated With Prickly Pear (Opuntia Ficus-Indica L.) Plantations, Souad Neffar, Taha Menasria, Haroun Chenchouni
Turkish Journal of Botany
The prickly pear (Opuntia ficus-indica L. Miller) is a xerophytic cactus species widely cultivated in arid and semiarid regions worldwide and used in rehabilitation programs of rangelands in Algeria since 1990. This study analyzed the diversity and functional traits of plant species established in prickly pear plantations growing under arid and semiarid climates. A 3-year plant assessment (2008-2010) was carried out using ecological descriptors (abundance, species richness, diversity indices, disturbance index, and Jaccard index) and plant functional traits (life forms, chorological types, dispersal types, Grime's, Noy-Meir's strategies, and morphological types). The results revealed 36 and 31 species in arid and …
Analysis Of Airborne Pollen Of Gümüşhane Province In Northeastern Turkey And Its Relationship With Meteorological Parameters, Yavuz Türkmen, Tali̇p Çeter, Nur Münevver Pinar
Analysis Of Airborne Pollen Of Gümüşhane Province In Northeastern Turkey And Its Relationship With Meteorological Parameters, Yavuz Türkmen, Tali̇p Çeter, Nur Münevver Pinar
Turkish Journal of Botany
Knowledge of the types of atmospheric pollen and their concentrations in a particular area is critical for evaluating air quality and allergen exposure. This study was carried out to determine the pollen diversity and daily, monthly, and annual concentrations in Gümüşhane, whose relationships were then sought with the meteorological factors in the atmosphere of Gümüşhane. For this purpose, an aerobiological study was carried out with Hirst (Burkard) type pollen traps in the Gümüşhane city center between August 2010 and July 2012. Sampling and analysis of the pollens followed the method described by the Spanish Aerobiological Network. The duration of the …
Two-Area Load Frequency Control With Redox Ow Battery Using Intelligentalgorithms In A Restructured Scenario, Lakshmi Dhandapani, Fathima Peer, Ranganath Muthu
Two-Area Load Frequency Control With Redox Ow Battery Using Intelligentalgorithms In A Restructured Scenario, Lakshmi Dhandapani, Fathima Peer, Ranganath Muthu
Turkish Journal of Electrical Engineering and Computer Sciences
Load frequency control (LFC) is an essential aspect of power system dynamics. This paper focuses on the optimization of LFC for a two-area deregulated power system under different scenarios. A recent nature-inspired ower pollination algorithm (FPA), based on the pollination process of plants, is used to tune the proportional integral (PI) controller parameters of LFC for the global minima solution. FPA is compared with a genetic algorithm, particle swarm optimization, and a conventional PI controller. During large load disturbance in the areas, controllers are incapable of reducing frequency deviations and tie-line power oscillations due to the slow response of the …
An Elitist Approach For Solving The Traveling Salesman Problem Using An Animalmigration Optimization Algorithm, Ezgi̇ Ülker
An Elitist Approach For Solving The Traveling Salesman Problem Using An Animalmigration Optimization Algorithm, Ezgi̇ Ülker
Turkish Journal of Electrical Engineering and Computer Sciences
This paper presents an improved version of the animal migration optimization (AMO) algorithm for solving the traveling salesman problem (TSP), which is classified as a combinatorial NP-hard problem. AMO is one of the recent metaheuristic algorithms inspired by the migration behavior of animals and has been efficiently applied to a variety of optimization problems. The algorithm is improved by reconstructing the neighborhood topology of each animal during the migration. This modified algorithm is called the elitist animal migration optimization (ELAMO) algorithm, since elitism is introduced as a way in which the positions of the leaders are considered for the neighborhood …
Volumetric 3d Reconstruction Of Real Objects Using Voxel Mapping Approach In A Multiple-Camera Environment, Tushar Jadhav, Kulbir Singh, Aditya Abhyankar
Volumetric 3d Reconstruction Of Real Objects Using Voxel Mapping Approach In A Multiple-Camera Environment, Tushar Jadhav, Kulbir Singh, Aditya Abhyankar
Turkish Journal of Electrical Engineering and Computer Sciences
Extracting 3D information from 2D images is an inverse estimation problem and a challenging task in itself. The aim of 2D to 3D reconstruction is to generate either a volume or a surface representing the object from multiple views. This paper presents a simple and accurate multiple-view volumetric 3D reconstruction method using an integrated approach based on homography estimation and voxel mapping. The homography-based approaches give accurate estimates but do not provide system dynamics. The voxel-based volumetric reconstruction methods provide system dynamics that are essential for system modeling. However, they face challenges while modeling the concavities. This paper presents a …
Circularly Polarized Implantable Antenna Characterization For Retinal Prosthesis Systems, Ademola Oluwaseun Kaka, Mehmet Toycan, Stuart Douglas Walker
Circularly Polarized Implantable Antenna Characterization For Retinal Prosthesis Systems, Ademola Oluwaseun Kaka, Mehmet Toycan, Stuart Douglas Walker
Turkish Journal of Electrical Engineering and Computer Sciences
We describe a miniaturized antenna design for retinal prosthesis applications that enhances data transfer between the implant and external camera. The circularly polarized and conformal 2.4--2.48 GHz microstrip patch antenna was simulated inside the vitreous humor and is intended for biomedical applications. Modified Hilbert and serpentine geometries were used for the proposed implant antenna design. Capacitive radiator loading offered miniaturized dimensions of 5.8 $\times $ 6.5 $\times $ 2 mm$^{3}$ (width $\times $ height $\times $ thickness mm$^{3})$. A truncated design enhanced the intrinsic circular polarization characteristics to $>$3 dB axial ratio. Polydimethylsiloxane substrate and superstrate materials were used …
Özyeğin Biopsy Robot: System Integration Architecture And Motion Compensation Of A Moving Target, Awais Ahmad, Özkan Bebek
Özyeğin Biopsy Robot: System Integration Architecture And Motion Compensation Of A Moving Target, Awais Ahmad, Özkan Bebek
Turkish Journal of Electrical Engineering and Computer Sciences
This paper presents the complete system architecture of a robotic biopsy system for real-time operations. The system has individual functional blocks working simultaneously including a 5 DoF parallel robot, ultrasound (US) imaging machine, two robotic manipulators, and a motion capturing system. Details of the real-time functionality of the robotic system components working with spatial and computational synchronization are presented. This paper also deals with a scenario in which the target tissue is moving due to the breathing of the patient. The motion of the needle tip and the target is tracked using US images as feedback. Two types of control …
User Interaction In Hands-Free Gaming: A Comparative Study Of Gaze-Voice And Touchscreen Interface Control, Muhtar Çağkan Uludağli, Cengi̇z Acartürk
User Interaction In Hands-Free Gaming: A Comparative Study Of Gaze-Voice And Touchscreen Interface Control, Muhtar Çağkan Uludağli, Cengi̇z Acartürk
Turkish Journal of Electrical Engineering and Computer Sciences
The goal of the present study is to contribute to the research on the use of eye tracking in hands-free gaming. We report the results of an experimental study by using a platform game designed by the authors. The game allowed gaze-voice command control, as well touchscreen control of the interface by the player. We employed a set of performance measures and we measured player engagement as an indicator of user experience. The findings revealed that the players did not improve in game performance when they used the gaze-voice control compared to the touchscreen control. On the other hand, they …
An Efficient Recurrent Fuzzy Cmac Model Based On A Dynamic-Group--Based Hybrid Evolutionary Algorithm For Identification And Prediction Applications, Chin-Ling Lee, Chengjian Lin
An Efficient Recurrent Fuzzy Cmac Model Based On A Dynamic-Group--Based Hybrid Evolutionary Algorithm For Identification And Prediction Applications, Chin-Ling Lee, Chengjian Lin
Turkish Journal of Electrical Engineering and Computer Sciences
This article presents an efficient TSK-type recurrent fuzzy cerebellar model articulation controller (T-RFCMAC) model based on a dynamic-group--based hybrid evolutionary algorithm (DGHEA) for solving identification and prediction problems. The proposed T-RFCMAC model is based on the traditional CMAC model and the Takagi--Sugeno--Kang (TSK) parametric fuzzy inference system. Otherwise, the recurrent network, which imports feedback links with a receptive field cell, is embedded in the T-RFCMAC model, and the feedback units are used as memory elements. The DGHEA, which is a hybrid of the dynamic-group quantum particle swarm optimization (QPSO) and the Nelder--Mead method, is proposed for adjusting the parameters of …
Adaptive Bit-Plane Selection-Based Low Complexity Motion Estimation For Screen Content Coding, Ramazan Duvar, Oğuzhan Urhan
Adaptive Bit-Plane Selection-Based Low Complexity Motion Estimation For Screen Content Coding, Ramazan Duvar, Oğuzhan Urhan
Turkish Journal of Electrical Engineering and Computer Sciences
Screen content video coding has become an emerging research topic with the spread of applications such as cloud gaming, screen/desktop virtualization, and mobile or external display interfacing. Screen content videos have different features compared to conventional camcorder-captured scenes. In this work, a novel low bit-depth representation-based motion estimation approach is proposed to exploit screen content specific features to improve coding efficiency. The proposed approach is based on an adaptive selection of Gray-coded bit-planes in order to generate low bit-depth representation of original screen content frames. The experimental results show that the motion estimation performance of the proposed approach is significantly …
Comparative Analysis Of Mabc With Knn, Som, And Aco Algorithms For Ecg Heartbeat Classification, Seli̇m Di̇lmaç, Zümray Ölmez, Tamer Ölmez
Comparative Analysis Of Mabc With Knn, Som, And Aco Algorithms For Ecg Heartbeat Classification, Seli̇m Di̇lmaç, Zümray Ölmez, Tamer Ölmez
Turkish Journal of Electrical Engineering and Computer Sciences
In this paper, we proposed a classification method based on a nature-inspired algorithm, i.e., modified artificial bee colony (MABC). This method was applied to electrocardiogram (ECG) heartbeat classification. ECG data was obtained from MITBIH database. Eight different types of heartbeats (N, j, V, F, f, A, a, and R) were analyzed. For a better classification result, both time domain and frequency domain features were used. Feature selection was done by divergence analysis. MABC classification accuracy and heartbeat sensitivity values were compared with the results of other methods. Among other classifiers, k-nearest neighbor (KNN), Kohonen's self-organizing map (SOM), and ant colony …
A Model-Based Transformation Framework For Designing And Analyzing Wireless Sensor Networks, Raoudha Saida, Yessine Hadj Kacem, Mohammed Sulaiman Bensaleh, Mohamed Abid
A Model-Based Transformation Framework For Designing And Analyzing Wireless Sensor Networks, Raoudha Saida, Yessine Hadj Kacem, Mohammed Sulaiman Bensaleh, Mohamed Abid
Turkish Journal of Electrical Engineering and Computer Sciences
Wireless sensor networks (WSNs) comprise resource-constrained (e.g., memory, processing, and energy) sensor nodes that are deployed in different areas and are able to monitor environmental conditions. Simulation has been widely used in order to evaluate the network performance. In this context, software designers need to evaluate, refine, and validate high-level models for WSN applications at early stages of development via simulation tools, in particular for WSN applications supporting energy-harvesting devices. In the present paper, we propose a model-based transformation framework that allows the modeling and simulation of a WSN system supporting energy-harvesting capabilities. In this proposal, we start from a …
Effects Of Cinnamic Acid On Complications Of Diabetes, Hati̇ce Gül Anlar, Merve Bacanli, Tuğbagül Çal, Sevtap Aydin, Nuray Ari, Ülkü Ündeğer Bucurgat, Ari̇f Ahmet Başaran, Ayşe Nurşen Başaran
Effects Of Cinnamic Acid On Complications Of Diabetes, Hati̇ce Gül Anlar, Merve Bacanli, Tuğbagül Çal, Sevtap Aydin, Nuray Ari, Ülkü Ündeğer Bucurgat, Ari̇f Ahmet Başaran, Ayşe Nurşen Başaran
Turkish Journal of Medical Sciences
Background/aim: Diabetes mellitus (DM) is a major health problem worldwide. Cinnamic acid (CA) and its derivatives are synthesized in plants and increasing attention has been given to them in recent years due to the high number of beneficial health properties attributed to their consumption. The aim of this study was to investigate the effects of CA on streptozotocin-induced diabetes in Wistar albino rats. Materials and methods: DNA damage was evaluated in the blood, liver, and kidney cells of rats by the alkaline comet assay. Oxidative stress parameters such as catalase, superoxide dismutase, glutathione reductase, glutathione-S-transferase, and glutathione peroxidase activities and …
In Vivo Attenuation Of Angiogenesis In Hepatocellular Carcinoma By Nigella Sativa, Moustafa Fathy, Toshio Nikaido
In Vivo Attenuation Of Angiogenesis In Hepatocellular Carcinoma By Nigella Sativa, Moustafa Fathy, Toshio Nikaido
Turkish Journal of Medical Sciences
Background/aim: Angiogenesis is imperative in malignant tumor growth. Hepatocellular carcinoma is a typical hypervascular tumor that relies on angiogenesis. The aim of this study is to investigate the in vivo molecular mechanism underlying the antitumor properties of Nigella sativa ethanolic extract (NSEE) through its antiangiogenic effect against diethyl nitrosamine (DENA)-induced hepatocarcinogenesis. Materials and methods: Male Wistar rats were divided into 4 groups: normal, NSEE, DENA, and NSEE-DENA groups. Final body weight, hepatosomatic indices, serum AFP, serum vascular endothelial growth factor (VEGF) levels, and liver tissue hepatocyte growth factor ß (HGFß) protein expression were estimated. Liver sections were stained for histological …
The Role Of Apoptosis And The Effect Of Epidermal Growth Factor On Proapoptotic Bnip 3 In An Experimental Rat Priapism Model, Osman Barut, Ahmet Karakeçi̇, Tunç Ozan, Fati̇h Firdolaş, Neci̇p Pi̇ri̇nççi̇, İrfan Orhan
The Role Of Apoptosis And The Effect Of Epidermal Growth Factor On Proapoptotic Bnip 3 In An Experimental Rat Priapism Model, Osman Barut, Ahmet Karakeçi̇, Tunç Ozan, Fati̇h Firdolaş, Neci̇p Pi̇ri̇nççi̇, İrfan Orhan
Turkish Journal of Medical Sciences
Background/aim: This study aimed to investigate the effects of apoptosis-inducing Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP 3) and antiapoptotic epidermal growth factor (EGF) on the pathophysiology of experimental low-flow priapism. Materials and methods: Twenty-four adult Sprague-Dawley rats were divided into four equal groups. Group I was the control group. Ischemic priapism was induced for 4 h in Group II rats. In Group III, intraperitoneal EGF at 10 µg/kg was given for 7 days before induction of ischemic priapism for 4 h. In Group IV, intraperitoneal EGF at 20 µg/kg was given for 7 days before induction of ischemic priapism …
The Brazelton Neonatal Behavioral Assessment Scale: A Validity And Reliability Study In A Turkish Sample, Öznur Başdaş, Emi̇ne Erdem, Ferhan Elmali, Seli̇m Kurtoğlu
The Brazelton Neonatal Behavioral Assessment Scale: A Validity And Reliability Study In A Turkish Sample, Öznur Başdaş, Emi̇ne Erdem, Ferhan Elmali, Seli̇m Kurtoğlu
Turkish Journal of Medical Sciences
Background/aim: The aim of the Brazelton Neonatal Behavioral Assessment Scale (BNBAS) is to gather a comprehensive pro le of neonatal functioning by describing the full range of neonatal behavior, including competencies and strengths, as well as di culties or deviations. is instrument has proved to be of great clinical value by detecting infants at risk for later developmental problems. is work was conducted methodologically with the aim of a Turkish validity and reliability study of the BNBAS. Materials and methods: The study was conducted in a large tertiary hospital in Turkey. After establishing content and language validity, the BNBAS was …
A Simplified Cell Culture Model For Research On Intestinal Inflammation, Ayşe Erol, Si̇bel Ti̇ryaki̇, Mustafa Orkan Ergün
A Simplified Cell Culture Model For Research On Intestinal Inflammation, Ayşe Erol, Si̇bel Ti̇ryaki̇, Mustafa Orkan Ergün
Turkish Journal of Medical Sciences
Background/aim: e aim of this study was to combine some easy and economical de ned methods and constitute a comprehensive cell culture model to use in the bowel diseases characterized by in ammation. Materials and methods: Induction of inflammation was performed using lipopolysaccharide (LPS) or a cytokine mixture (TNF-?: 10 ng/mL; IFN-?: 100 ng/mL; IL-1ß: 1 ng/mL). IEC-6 cells were grown to con uence and serum-starved, wounds were constituted, and progress of cell migration into the wounds was photographed at 0, 2, 4, 6, 8, 10, 12, and 24 h in the presence or absence of an in ammatory environment. …
Comparison Between Iloprost And Alprostadil For Protection Againstischemia/Reperfusion Injury In A Rat Model, Deni̇z Çevi̇rme, Taylan Adademi̇r, Eylül Kafali Başaran, Ömer Faruk Şavluk, Ahmet Eli̇bol, Gözde Erkanli Şentürk, Hati̇ce Akkaya, Bayram Yilmaz
Comparison Between Iloprost And Alprostadil For Protection Againstischemia/Reperfusion Injury In A Rat Model, Deni̇z Çevi̇rme, Taylan Adademi̇r, Eylül Kafali Başaran, Ömer Faruk Şavluk, Ahmet Eli̇bol, Gözde Erkanli Şentürk, Hati̇ce Akkaya, Bayram Yilmaz
Turkish Journal of Medical Sciences
Background/aim: Alprostadil and iloprost are successful agents used for both pulmonary hypertension and extremity ischemia treatment. Different systemic effects of these agents may change the preferences of clinical usage. Superiority of preventing ischemia/ reperfusion (IR) injury is a criterion for clinical preference of these agents. The present study was designed to compare the protective effects of alprostadil and iloprost in a rat model of IR injury. Materials and methods: Twenty-three male Sprague Dawley rats were used (aged 8-12 weeks, mean weight 230 ± 30 g). They were randomized into 4 groups: Group 1 (iloprost + IR), Group 2 (alprostadil + …
Investigation Of Phikz Phage Therapy Against Pseudomonas Aeruginosa In Mousepneumonia Model, Kübra Can, Uğur Aksu, Osman Şadi̇ Yenen
Investigation Of Phikz Phage Therapy Against Pseudomonas Aeruginosa In Mousepneumonia Model, Kübra Can, Uğur Aksu, Osman Şadi̇ Yenen
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate the effects of PhiKZ phage therapy and meropenem alone or combined treatments in a pneumonia mouse model induced by the Pseudomonas aeruginosa PAO1 strain. The cross-talk between lungs and kidneys was also determined. Materials and methods: The systemic, lung-specific, and kidney-specific inflammation levels and the bacterial load in lung tissue and biochemical parameters were investigated after PhiKZ phage therapy and meropenem alone or combined treatments in a pneumonia mouse model induced by the P. aeruginosa PAO1 strain. The cross-talk between lungs and kidneys was also determined by measuring plasma levels of …
Se33 Locus As A Reliable Genetic Marker For Forensic Dna Analysis Systems, Dr Munir Ahmad Bhinder, Muhammad Yasir Zahoor, Haleema Sadia, Muhammad Qasim, Rukhsana Perveen, Ghulam Murtaza Anjum, Muhammad Iqbal, Najeeb Ullah, Waseem Shehzad, Muhammad Tariq, Ali Muhammad Waryah
Se33 Locus As A Reliable Genetic Marker For Forensic Dna Analysis Systems, Dr Munir Ahmad Bhinder, Muhammad Yasir Zahoor, Haleema Sadia, Muhammad Qasim, Rukhsana Perveen, Ghulam Murtaza Anjum, Muhammad Iqbal, Najeeb Ullah, Waseem Shehzad, Muhammad Tariq, Ali Muhammad Waryah
Turkish Journal of Medical Sciences
Background/aim: Genetic variation, an authentic tool of individual discrimination, is being used for forensic investigations worldwide. A missing result for even one out of 13-17 markers leads to an inconclusive report. Additional reliable markers are required to compensate such deficiencies. The SE33 locus has high genetic variability in different populations and is being used in forensic investigation systems in some countries. The purpose of the study was to assess the viability of use of the SE33 locus as a supportive marker for forensic DNA profiling. Materials and methods: Amplification of the SE33 locus was performed using the PowerPlex ES Monoplex …
Effect Of Phosphodiesterase-5 Inhibition On Joint And Muscle Damage In Rats Withadjuvant Arthritis, Fai̇ze Eli̇f Bahadir, Mustafa Kutay Köroğlu, Meral Yüksel, Feri̇ha Ercan, Yaşar İnci̇ Ali̇can
Effect Of Phosphodiesterase-5 Inhibition On Joint And Muscle Damage In Rats Withadjuvant Arthritis, Fai̇ze Eli̇f Bahadir, Mustafa Kutay Köroğlu, Meral Yüksel, Feri̇ha Ercan, Yaşar İnci̇ Ali̇can
Turkish Journal of Medical Sciences
Background/aim: This study was designed to examine the effect of tadalafil, a phosphodiesterase (PDE)5 inhibitor, on the severity of joint and muscle damage in rats with adjuvant-induced arthritis (AA). Materials and methods: AA was induced by intradermal inoculation into right hind paw of male Sprague Dawley rats (300-450g) with complete Freund's adjuvant (CFA; 0.1 mL). AA rats were treated with either tadalafil (10 mg/kg; per oral) alone or along with the soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ; 10 mg/kg; intraperitoneally). After decapitation on day 16, trunk blood was collected for total oxidant status (TOS) and total antioxidant capacity (TAC) assays. …
Effect Of Cineole, Alpha-Pinene, And Camphor On Survivability Of Skin Flaps, Bi̇lsev İnce, Mehmet Dadaci, İbrahi̇m Kilinç, Pembe Oltulu, Serhat Yarar, Mehmet Uyar
Effect Of Cineole, Alpha-Pinene, And Camphor On Survivability Of Skin Flaps, Bi̇lsev İnce, Mehmet Dadaci, İbrahi̇m Kilinç, Pembe Oltulu, Serhat Yarar, Mehmet Uyar
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the specific component of Rosmarinus officinalis (RO) responsible for increased flap survival and how RO displays its efficacy. Materials and methods: Rectangular random-pattern flaps were elevated from the back of each rat. Group I was the control group. In group II 0.1 mL of cineole, in group III 0.1 mL of alpha-pinene, in group IV 0.1 mL of camphor, in group V 0.1 mL each of alpha-pinene and cineole, in group VI 0.1 mL each of alpha-pinene and camphor, in group VII 0.1 mL each of cineole and camphor, and in …
The Effect Of Low Molecular Weight Heparin On Salvaging The Zone Of Stasis In Anexperimental Burn Model, Muhammet Uraloğlu, Murat Li̇vaoğlu, Özgür Agdoğan, Şafak Ersöz, Ümi̇t Naci̇ Karaçal
The Effect Of Low Molecular Weight Heparin On Salvaging The Zone Of Stasis In Anexperimental Burn Model, Muhammet Uraloğlu, Murat Li̇vaoğlu, Özgür Agdoğan, Şafak Ersöz, Ümi̇t Naci̇ Karaçal
Turkish Journal of Medical Sciences
Background/aim: Multiple zones of injuries are formed after burns, consisting of a zone of coagulative necrosis, a zone of hyperemia, and a zone of stasis, in which progressive microcirculatory thrombosis leads to degeneration and deepening of the wound. We used an experimental rat comb burn model to test the hypothesis that use of low molecular weight heparin (LMWH) may save the zone of stasis. Materials and methods: Adult female rats were randomly divided two groups: the LMWH group (n = 8) rats received subcutaneous LMWH injections, while the saline group (n = 8) rats were injected with the same volume …