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South Dakota State University

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The Impacts Of Land Use And Land Cover Change On Water Quality In The Big Sioux River: 2007-2016, Dinesh Shrestha Jan 2019

The Impacts Of Land Use And Land Cover Change On Water Quality In The Big Sioux River: 2007-2016, Dinesh Shrestha

Electronic Theses and Dissertations

Between 2006 and 2012, conversion of 485,000 acres of grassland to cropland in eastern South Dakota was reported. In 2012, the Big Sioux River (BSR) running through most of eastern South Dakota was listed among the dirtiest rivers in the nation. This rating convinced state authorities to study trends of land cover changes in the BSR watershed and its association with BSR water quality with respect to increases in nitrate levels. This research i) quantifies spatial and temporal changes in the land cover types within the BSR watershed, and ii) identifies any correlation between these changes and changes in BSR …

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Evaluation Of Effects Of Methods Used For Forage Analysis And Dietary Inclusion Of Buffer On Fiber Digestibility And Rumen Fermentation In Diets High In Distillers Grains, Lydia Kehinde Olagunju Jan 2019

Evaluation Of Effects Of Methods Used For Forage Analysis And Dietary Inclusion Of Buffer On Fiber Digestibility And Rumen Fermentation In Diets High In Distillers Grains, Lydia Kehinde Olagunju

Electronic Theses and Dissertations

Forage quality is an important factor affecting intake and utilization of forage, thus making it imperative to evaluate the methods used to determine the nutritive values of forage in order to predict animal performance. Additionally, fibrous feeds for ruminants are less subject to competitive demand. The plant cell wall is the largest hindrance to complete digestion of feeds, particularly forages and by-products and to the utilization of the nutrients and energy they contain, necessitating effective strategies for increasing the rate and efficiency of utilization of forage fiber and the energy therein. It is critically important to increase fiber digestion for …

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Evaluation Of Flax Oil Supplementation On Performance Of Growing Dairy Heifer Calves And Lactating Cows, Chelsea Rose Schossow Jan 2019

Evaluation Of Flax Oil Supplementation On Performance Of Growing Dairy Heifer Calves And Lactating Cows, Chelsea Rose Schossow

Electronic Theses and Dissertations

Utilization of flax oil is new to the livestock industry, and limited research has been done to see the benefits of feeding the highly unsaturated oil to both dairy calves and lactating cows. Two studies were conducted to evaluate the potential benefits of flax oil as a lipid supplement. The first study compared the supplementation of two plant based oils to growing dairy calves. Thirty-six female Holstein calves in individual hutches were used in a 12-wk randomized complete block design study. Treatments were: 1) control (CON) with no oil, 2) 80 g/d of flax oil (FLAX), and 3) and 80 …

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Escherichia Coli Removal From Stormwater Using Steel Chips Filter, Peng Dai Jan 2019

Escherichia Coli Removal From Stormwater Using Steel Chips Filter, Peng Dai

Electronic Theses and Dissertations

Media filtration has received increasing attention as an effective technology that can facilitate the removal of particles and dissolved pollutions in the stormwater. However, most traditional media filtration systems are generally ineffective in removing bacteria, causing pollution of groundwater and receiving surface water. In this study, recycled steel chips were evaluated as low-cost filter materials for bacterial removal from stormwater. Laboratory column experiments were conducted to evaluate the impact of steel chips particle size, flow rate, initial E.coli concentration, pH, natural organic matter (NOM), steady and intermittent flow on E.coli removal. The results showed that E.coli removal decreased from 99.4% …

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Development Of A Novel Nanotechnology-Based Vaccine Adjuvant And Delivery System For Systemic And Mucosal Immunity, Mohammed Ali Bakkari Jan 2019

Development Of A Novel Nanotechnology-Based Vaccine Adjuvant And Delivery System For Systemic And Mucosal Immunity, Mohammed Ali Bakkari

Electronic Theses and Dissertations

Many serious infections for which there are no existing vaccines, enter by a mucosal route such as HIV, influenza, and tuberculosis, etc. Therefore, designing safe and effective mucosal vaccines that elicit robust immune response at mucosal sites is still a major challenge without a safe mucosal adjuvant. Previously, our laboratory had discovered inulin acetate as a novel toll-like-receptor-4 agonist (adjuvant). The study in this dissertation explored the application of nanoparticles prepared with inulin acetate (InAc-NPs) as a vaccine adjuvant and delivery system for enhancing mucosal immunity. The rationale behind selecting InAc-NPs is their proven ability to activate strong systemic immunity …

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Cropping Sequence Affects Subsequent Soybean Yield, Soil Microbiome And Soil Health, Izzet Bulbul Jan 2019

Cropping Sequence Affects Subsequent Soybean Yield, Soil Microbiome And Soil Health, Izzet Bulbul

Electronic Theses and Dissertations

Rotation is an important cultural practice that farmers use to manage crop growth and diseases. Diversified crop rotations directly affect plant residue inputs that may enrich specific groups of microbes that form beneficial associations with the following crop. At two field sites, yield differences were observed in soybeans planted after the following four long-term (14 year) crop sequences: continuous corn (CC), corn (Zea mays)/corn/soybean (Glycine max) (CCS), corn/soybean/corn (CSC), soybean/corn/soybean (SCS). Soybean yields were in decreasing order, CC>CCS>CSC>SCS, and the yield differences could not be explained by soil chemical and physical properties previously …

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Maximizing Ecosystem Services Provided To The New Oil Crop Brassica Carinata Through Landscape And Arthropod Diversity, Shane Stiles Jan 2019

Maximizing Ecosystem Services Provided To The New Oil Crop Brassica Carinata Through Landscape And Arthropod Diversity, Shane Stiles

Electronic Theses and Dissertations

Prairies, once spanning the Upper Midwest, have now largely been replaced by agriculture. The lack of resources available to pollinators in agricultural fields and the practices employed by farmers to maximize yield has led to a decline in insect and pollinator diversity. There is a need to better understand how ecosystem services provided by a diverse insect community scale to current farming practices as they relate to crop yield. We sought to explain how landscape heterogeneity relates to insect and pollinator diversity, as well as how insect diversity relates to crop yield across common farming practices. To evaluate how farming …

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Pilot Scale Evaluation Of E. Coli Filtration Removal From Stormwater Using Recycled Steel, Jason Neville Jan 2019

Pilot Scale Evaluation Of E. Coli Filtration Removal From Stormwater Using Recycled Steel, Jason Neville

Electronic Theses and Dissertations

Microbial pathogens are considered one of the most important pollutants in regards to surface waters such as coastal waters, rivers and urban estuaries. Escherichia Coli (E. coli) is a bacterial microorganism found in the guts of humans and some animals that if ingested can cause diarrhea, severe stomach cramps, and vomiting. E. coli carried by stormwater runoff can deteriorate water quality of receiving bodies of water. It is necessary to develop technologies to remove E. coli from stormwater runoff to protect surface waters and public health. The use of steel byproducts as an adsorption technology is an emerging stormwater treatment …

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Mass Spectrometry-Based Quantitative Proteomic Analysis Of Biological Fluids, Patience Akosua Afedi Jan 2019

Mass Spectrometry-Based Quantitative Proteomic Analysis Of Biological Fluids, Patience Akosua Afedi

Electronic Theses and Dissertations

Proteomics is a high-throughput approach to study protein expression, structure, function, interaction, post-translational modifications, and localization in a cell or tissue. Proteomic shotgun approach was used to analyze changes in proteins in bovine follicular fluid (FF) and plasma (PL) from cows with high estradiol (HE2) or low E2 (LE2) during the preovulatory period. FF creates a unique microenvironment in follicles necessary for follicle growth and oocyte maturation, and pre-ovulatory concentrations of E2 have been reported to impact several processes involved with fertility. Initial steps in the analysis involved development of an immunodepletion protocol for high abundant proteins (HAPs) in bovine …

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Parents In Urbanized Areas And Their Perception Of 4-H Youth Development Programs, Matthew Ryan Olson Jan 2019

Parents In Urbanized Areas And Their Perception Of 4-H Youth Development Programs, Matthew Ryan Olson

Electronic Theses and Dissertations

This study examined the perceptions held by parents living in the urbanized area of Rapid City, South Dakota, to determine if artificial barriers to joining 4-H PYD programs existed. Through snowball sampling methods, nine participants were recruited to engage in semi-structured interviews. Transcripts from the interviews were coded utilizing in vivo and axial coding methods. Four themes emerged from the interviews: characteristics of youth development programs, program promotion through school flyers, barriers to joining youth development programs, and 4-H and its connection to agriculture. The major recommendation for 4-H professionals is to focus on leadership, life skills, and character development …

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Anabolic Hormone Exposure During Various Stages Of Growth: Effects On Post-Weaning Performance, Frame Size, And Carcass Characteristics Of Calf-Fed Steers, Wesley W. Gentry Jan 2019

Anabolic Hormone Exposure During Various Stages Of Growth: Effects On Post-Weaning Performance, Frame Size, And Carcass Characteristics Of Calf-Fed Steers, Wesley W. Gentry

Electronic Theses and Dissertations

The growth promoting activity of implants have been documented. However, stage of growth in which the implant is administered may alter growth performance and carcass traits. An experiment was conducted to examine the effects of administering a conventional implant (Synovex C; SYN-C), or an extended-release combination implant (Synovex One Grass; ONE-G) to suckling steer calves on weaning weight, post-weaning growth performance, and carcass characteristics. Suckling steer calves were either not implanted (NONE) or were implanted with SYN-C or ONE-G. Steer calves were predominantly 30 to 60 d of age when implants were administered. Steers were weaned 176 d post-suckling implant …

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Identifying An Optimal Bald Eagle Monitoring Program For Southwest Alaska National Parks, Rebecca Kolstrom Jan 2019

Identifying An Optimal Bald Eagle Monitoring Program For Southwest Alaska National Parks, Rebecca Kolstrom

Electronic Theses and Dissertations

The Southwest Alaska Inventory and Monitoring Network includes bald eagle monitoring as part of their Vital Signs Monitoring Plan. Lake Clark National Park and Preserve, Katmai National Park and Preserve, Kenai Fjords National Park, and Wrangell – St. Elias National Park and Preserve monitor bald eagles annually, albeit slightly differently among parks. Since monitoring decisions involve multiple objectives and stakeholders, there was a need for a structured approach to identify an optimal monitoring program. We used a structured decision making process and an iterative, four-round Delphi Process to collect information about long-term bald eagle monitoring from experts. We collected information …

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Assessing Listeria Risk During Different Stages Of Ice Cream Manufacturing And Storage, Neha Singh Jan 2019

Assessing Listeria Risk During Different Stages Of Ice Cream Manufacturing And Storage, Neha Singh

Electronic Theses and Dissertations

Listeriosis is a life-threatening infection caused by foods contaminated with Listeria monocytogenes. Some of the major ice cream recalls in recent years reaffirm the ability of this food-borne pathogen to survive in diverse dairy processing environments and cause cross contamination. Inspection reports revealed certain lapses in implementing adequate hygienic practices for Listeria persistence in the processing environment, leading to cross contamination of ice cream. The higher levels of cross contamination of raw ice cream mix might result in random heat-injured cells when exposed to minimum heat treatment (69°C for 30 min). Evidence about the presence of injured cells in ice …

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The Efficacy Of Protein Supplementation On Attenuating Muscle Atrophy Following Disuse In The Collegiate Population, Leah Kroeger Jan 2019

The Efficacy Of Protein Supplementation On Attenuating Muscle Atrophy Following Disuse In The Collegiate Population, Leah Kroeger

Electronic Theses and Dissertations

The purpose of this study is to determine the effects of a protein supplementation protocol through a period of muscular disuse in maintaining muscle mass, strength, jump force production, and cross-sectional area in the collegiate population. Two groups of healthy collegiate participants underwent two weeks of unilateral lower limb suspension (ULLS), during which the control group consumed a normal diet and the treatment group received an additional 75 g of protein supplementation. Lean mass, strength, and force production were measured between dietary intakes at baseline and following immobilization. Muscle area was lost between both groups following ULLS (treatment, - 282.8 …

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Effects Of Oats And Distiller’S Dried Grains Fibers On Fortification Of Asian Noodles – Evaluation Of Glycemic Response, Noodle Quality And Nutritional Composition, Kara Konst Jan 2019

Effects Of Oats And Distiller’S Dried Grains Fibers On Fortification Of Asian Noodles – Evaluation Of Glycemic Response, Noodle Quality And Nutritional Composition, Kara Konst

Electronic Theses and Dissertations

The objective of this study was to develop Asian wheat noodle formulations enriched with oat flour and corn DDG at 10, 20 and 30 % wheat flour replacement levels and to evaluate the effects of this fiber and protein enrichment on the glycemic response of human subjects. We hypothesized that the addition of high-fiber oats and high-fiber, high-protein DDG will have synergistic effects in lowering the glycemic response in human subjects. In this study, steamed instant Asian noodles were prepared with DDG(D) and oats(OF) in combination with all-purpose wheat flour(W) in the following flour blends: (W:D) 90:10, (W:OF) 90:10, (W:D) …

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Effect Of Water Velocity And Temperature On Energy Use, Behavior, And Mortality Of Pallid Sturgeon Scaphirhynchus Albus Larvae, Joseph Thomas Mrnak Jan 2019

Effect Of Water Velocity And Temperature On Energy Use, Behavior, And Mortality Of Pallid Sturgeon Scaphirhynchus Albus Larvae, Joseph Thomas Mrnak

Electronic Theses and Dissertations

Pallid Sturgeon Scaphirhynchus albus are a federally endangered species endemic to the Missouri River basin. Natural reproduction has been limited for decades and a recruitment bottleneck is hypothesized to occur during the larval stage of development. Understanding factors that affect survival of Pallid Sturgeon larvae is key given their critical status and ongoing recovery efforts. In this study, I evaluated the effects of water velocity and temperature on energy use, behavior, and mortality of endogenously feeding Pallid Sturgeon larvae (< 25 mm TL). In the first experiment, I examined the effect of water velocity (0 – 8.3 cm s−1) on larval growth, energy density, swimming activity, and mortality. Larval growth rate at 16.3 °C was similar across …

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Effect Of Mineral Ions On The Functional Properties Of Starch Films, Aliza Sigdel Jan 2019

Effect Of Mineral Ions On The Functional Properties Of Starch Films, Aliza Sigdel

Electronic Theses and Dissertations

Essential minerals are indispensable inorganic micronutrients that modulate vital physiological functions at the molecular level. Their deficiency, though required in small amounts, impairs health significantly. Their supplementation through diet is prudent and carbohydrates standout as favorable choice. Carbohydrates, starches and polysaccharides, exhibit unique chemical structures and functionalities, and interact with mineral ions in several ways. The aim of this research is to investigate the effect of mineral ions on the physicochemical properties, tensile strength and in vitro starch digestion of starch-films. Corn starch and potato starch along with Fe2+, Mn2+, Cu2+ and Zn2+ ions have been chosen as model starch …

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A New Lens: Psychological Ownership As An Element To Promoting Organizational Change, Tyler Carlson Jan 2019

A New Lens: Psychological Ownership As An Element To Promoting Organizational Change, Tyler Carlson

Electronic Theses and Dissertations

Much of the change management literature has focused on change from the perspective of the organization as a whole. However, researchers have begun to explore the impact change has on employees, as well as employee perceptions of organizational change. The current study explored the role psychological ownership has in the context of organizational change, by using it is as a moderator between employee openness to organizational change (EOOC), and organizational commitment, job stress, and turnover intentions. Results revealed a significant positive correlation between EOOC and organizational commitment, a significant negative correlation between EOOC and job stress, as well as turnover …

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In-Silico Design And Synthesis Of Selective Estrogen Receptor Modulators Targeting Ovarian Cancer, John Apraku Jan 2019

In-Silico Design And Synthesis Of Selective Estrogen Receptor Modulators Targeting Ovarian Cancer, John Apraku

Electronic Theses and Dissertations

The established records of the safety of Ormeloxifene along with its favorable bioavailability and ability to inhibit rapid cell proliferation in the endometrium during embryonic implantation has made it one of the best drug candidates for controlling undesirable rapid cell growth such as endometriosis and cancerous tumor conditions. Recent studies have confirmed the effectiveness of Ormeloxifene to suppress and inhibit epithelial-mesenchymal transition process as evidenced by repression of N-cadherin, slug, snail, vimentin, MMPs, β-catenin/TCF-4 transcriptional activity and induce the expression of pGSK3b. Recently conducted studies have revealed the dynamic binding of ormeloxifene with β-catenin, GSK3b, CDK4, and other downstream EGFR. …

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Menstrual Cycle And The Vascular Properties Of Remote Preconditioning, Shelby Rachel Jan 2019

Menstrual Cycle And The Vascular Properties Of Remote Preconditioning, Shelby Rachel

Electronic Theses and Dissertations

PURPOSE: A promising therapeutic intervention to counteract endothelial ischemia/reperfusion (I/R) injury is ischemic preconditioning (IPC). Limited data from ovariectomized animal models shows that estrogen deficiency abolishes the cardioprotective effects of IPC, whereas estrogen replacement restores protection. This suggests that alterations in female sex hormones, particularly estrogens, that occur naturally during the menstrual cycle is likely to influence the vascular protective properties of IPC. The aim of the present study was to identify how changes in female sex hormones that occur naturally during the menstrual cycle interfere with IPC to provide vascular endothelial protection in women. METHODS: Nine healthy premenopausal eumenorrheic …

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Developing Food Quality Standards For Distiller’S Dried Grains – Evaluating Composition Quality And Safety, Tanvee Deshpande Jan 2019

Developing Food Quality Standards For Distiller’S Dried Grains – Evaluating Composition Quality And Safety, Tanvee Deshpande

Electronic Theses and Dissertations

Introduction: Distillers Grains represent a major co-product of corn ethanol production. At the production rate of 44 million tons/year and a price of $95/ton, this co-product has potential as a food ingredient (solvent-treated dried products) owing to its high protein content (38%) and high fiber content (40%TDF). The aim of the research was to determine the composition, quality and safety of several initial moisture types of distiller’s grains – distiller’s grains without solubles (DG) and distiller’s grains with solubles (DGS) in wet and freeze-dried form (FrD) from 2017 and 2018.
Method: Processing methods were optimized for raw DG & DGS …

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Role Of Microglial Α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator In Animal Model Of Major Depressive Disorder, Sami Alzarea Jan 2019

Role Of Microglial Α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator In Animal Model Of Major Depressive Disorder, Sami Alzarea

Electronic Theses and Dissertations

Major depressive disorder (MDD) is the most prevalent psychiatric disorder, affecting about 10% of the global population and is the leading cause of disability in USA. Nearly one-third of depressed patients fail to respond to conventional antidepressant therapies. Therefore, novel therapies are needed, and require a new target and molecular mechanisms underlying MDD. Brain glial mechanisms, specifically, microglial α7 nicotinic acetylcholine receptors (nAChRs) have been proposed as an important target for MDD associated with neuroinflammation. We hypothesized that microglial α7 nAChRs positive allosteric modulator (PAM) has an important role in the regulation of behavioral, cellular, biochemical and molecular mechanisms underlying …

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Investigating Anions And Hydrophobicity Of Deep Eutectic Solvents By Experiment And Computational Simulation, Amos Kwabena Dwamena Jan 2019

Investigating Anions And Hydrophobicity Of Deep Eutectic Solvents By Experiment And Computational Simulation, Amos Kwabena Dwamena

Electronic Theses and Dissertations

Deep eutectic solvents are a new generation of ionic liquid-like solvents formed by combining hydrogen bond acceptor with hydrogen bond donor which result in the depression of the melting point of the solvent. Like ionic liquids, anions play a critical role in tuning the polarity, physicochemical properties, and thermodynamic behavior of deep eutectic solvent (DES). Choline chloride is the most widely used quaternary ammonium salt (QAS) in the literature and has remarkable advantages from reduced cost to low toxicity and volatility. Choline bromide and choline iodide are other QAS that have not been used often for DES synthesis and applications, …

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Undoing Gender: An Analysis Of How Women Communicate Within The Agricultural Industry, Shala R. Larson Jan 2019

Undoing Gender: An Analysis Of How Women Communicate Within The Agricultural Industry, Shala R. Larson

Electronic Theses and Dissertations

In recent history, women have entered more business-like positions in the agricultural industry. This thesis seeks to understand how women in agriculture describe their workplace communication and whether they feel they are part of a muted group. Twelve women were interviewed regarding their experiences as women in agriculture and were asked whether they feel valued in their positions and how they communicate with their male co-workers. Specifically, interviewees were asked if they ever felt the need to alter their communication to complement, emulate, or otherwise adjust to masculine communication styles. The majority of women interviewed reported having to strategically choose …

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Advanced Analysis Of Compounds Of Toxicological Importance By Ice Concentration Linked With Extractive Stirrer (Icecles) Gc-Ms And Rp-Hplc-Esi-Ms-Ms, Joseph K. Dzisam Jan 2019

Advanced Analysis Of Compounds Of Toxicological Importance By Ice Concentration Linked With Extractive Stirrer (Icecles) Gc-Ms And Rp-Hplc-Esi-Ms-Ms, Joseph K. Dzisam

Electronic Theses and Dissertations

Cyanide and nitrosoamines (NAs) are ubiquitous compounds, found in our food and water, either by natural process or through man-made activities. The toxicity of cyanide is exerted by its ability to inhibit metalloenzymes such as cytochrome c oxidase, causing concomitant cascades of biochemical effects such as lactic acidosis, inhibition of ATP production, respiratory seizure, and potential death. Nitrosoamines, on the other hand, undergo biotransformation (metabolic activation in cytochrome P450) in the body to produce unstable intermediates that alkylate DNA, causing mutations, and leading to carcinogenesis. In order to further the advancement of a promising cyanide, cobinamide (Cbi), an LC-MS-MS method …

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Diversifying Cornfields By Interseeding Cover Crops: Practical Implications And The Response Of Invertebrate Communities, Michael Bredeson Jan 2019

Diversifying Cornfields By Interseeding Cover Crops: Practical Implications And The Response Of Invertebrate Communities, Michael Bredeson

Electronic Theses and Dissertations

The lack of suitable habitat conditions for beneficial organisms in simplified agroecosystems leads to unstable invertebrate communities and overreliance on chemical control of herbivores. It is possible to manage pest populations without agrichemicals by manipulating farmland so that herbivores are impaired by plant-driven bottom-up and enemy-driven top-down antagonisms. Interseeding cover crops between established crop rows is a method used by farmers to improve habitat suitability for natural enemies and hinder host-finding, feeding and movement by herbivores. Here I address three important research gaps related to interseeding cover crops. A calcium carbonate seed coating, used to improve seed-broadcasting efficiency, was tested …

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Effects Of Energy Development On Movements, Home Ranges, And Resource Selection Of White-Tailed Deer In The Western Dakotas, Bailey S. Gullikson Jan 2019

Effects Of Energy Development On Movements, Home Ranges, And Resource Selection Of White-Tailed Deer In The Western Dakotas, Bailey S. Gullikson

Electronic Theses and Dissertations

Oil and natural gas development has increased in recent years and research is needed to assess potential impacts on white-tailed deer (Odocoileus virginianus) populations. Our objectives were to document movements, home ranges, and resource selection of female white-tailed deer in response to energy development in the western Dakotas. Our study areas included Dunn County, North Dakota, an area with current oil and gas development, and Grant County, North Dakota, and Perkins County, South Dakota, areas without current oil and gas development. We captured and fitted 150 female deer with Very High Frequency (VHF) collars across study sites, and …

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Estimating Soil Organic Carbon In Cultivated Soils Using Soil Test Data, Remote Sensing Imagery From Satellites (Landsat 8 And Plantscope), And Web Soil Survey Data, Muhammed Halil Koparan Jan 2019

Estimating Soil Organic Carbon In Cultivated Soils Using Soil Test Data, Remote Sensing Imagery From Satellites (Landsat 8 And Plantscope), And Web Soil Survey Data, Muhammed Halil Koparan

Electronic Theses and Dissertations

Soil organic carbon (SOC) is an important soil parameter of cultivated soils that needs to be monitored and mapped regularly to enhance soil health and productivity. SOC levels in cultivated areas is difficult to monitor for farmers and is costly to analyze using traditional methods. The objective of this study was to estimate surface SOC distribution in selected soils of Major Land Resource Areas (MLRA) 102A (Rolling Till Plain, Brookings County, SD) and 103 (Central Iowa and Minnesota Till Prairies, Lac qui Parle County, MN) using soil sample data, Web Soil Survey (WSS) data, and satellite imagery (Landsat 8 and …

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Evaluation Of The Effect Of Carvedilol On The Thioredoxin Pathway In H9c2 Rat Cardiomyocytes, Metab Alharbi Jan 2019

Evaluation Of The Effect Of Carvedilol On The Thioredoxin Pathway In H9c2 Rat Cardiomyocytes, Metab Alharbi

Electronic Theses and Dissertations

The thioredoxin (Trx) system is an endogenous antioxidant system that affects cell function and survival through controlling cellular redox status. Trx and TrxR are the main enzymes in this system while thioredoxin interacting protein (TXNIP) is a negative regulator. This study’s goal was to better understand the Trx system’s involvement in the cardiovascular disease and modulate the pathway through drug treatment. Carvedilol is a non-selective β-blocker that also exhibits antioxidant properties, but the exact mechanism of the antioxidant effect is still unclear. H9c2 rat cardiomyocytes were used to examine the effect of carvedilol on the Trx system under normal conditions. …

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Impacts Of Small Intestinal Enzyme Activity And Varying Corn Grain Processing Types On Feeding Behavior, And Growth Performance Of Finishing Beef Steers, Wyatt Smith Jan 2019

Impacts Of Small Intestinal Enzyme Activity And Varying Corn Grain Processing Types On Feeding Behavior, And Growth Performance Of Finishing Beef Steers, Wyatt Smith

Electronic Theses and Dissertations

The objective of this study was to quantify the differences in activity of jejunal maltase and isomaltase between 2 groups of steers with average dry matter intake (DMI) and differing average daily gain (ADG). Dry matter intake and ADG were measured in crossbred steers (n = 69). Jejunal mucosal samples were collected from 8 steers with the greatest (high) or least (low) ADG and average DMI (± 0.55 standard deviation). Homogenates of jejunal mucosa were incubated with increasing amounts of maltose and isomaltose to determine the disaccharidase kinetics. Neither the Km of isomaltase (P = 0.15) or maltase (P = …

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