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Salam Neighbor: Syrian Refugees Through The Camera Lens, Lava Asaad Sep 2019

Salam Neighbor: Syrian Refugees Through The Camera Lens, Lava Asaad

CLCWeb: Comparative Literature and Culture

This paper examines the documentary Salam Neighbor (2015), which celebrates the will of Syrian refugee women who are displaced in Jordan. The collective experience of the refugees portrayed in the documentary solicits a reaction from the Western viewer. To counteract the images of refugees in the media, documentaries can be a good alternative for mass media, which has been perpetuating a binary of the West and the Rest. The argument tackles the issue of this new representation of refugees in documentaries within a postcolonial paradigm of how we represent or speak to/with the Other in our technological age, as well …


Recovering The Archive And Finding Forgiveness In Park’S The Truth Commissioner, Aleksandra Hajduczek Sep 2019

Recovering The Archive And Finding Forgiveness In Park’S The Truth Commissioner, Aleksandra Hajduczek

CLCWeb: Comparative Literature and Culture

In her article “Recovering the Archive and Finding Forgiveness in Park’s The Truth Commissioner,” the author utilizes Jacque Derrida's theories about the function of archivization and the “impossible madness” of pure forgiveness to examine how these issues are addressed in post peace process Troubles fiction, focusing specifically on David Park's 2008 novel The Truth Commissioner. Park's text provides a particularly relevant example of the tension that Derrida outlines between the need for an unconditional, pure, and "hyperbolic" forgiveness and the conditional, judicial forgiveness that he associates with the truth recovery process.


Introduction To Suffering, Endurance, Understanding: New Discourses Within Philosophy And Literature, Douglas S. Berman Sep 2019

Introduction To Suffering, Endurance, Understanding: New Discourses Within Philosophy And Literature, Douglas S. Berman

CLCWeb: Comparative Literature and Culture

Literature is generally seen as depicting the lives of human subjects through their unique narratives. And that, while its endpoint may be universal, it is typically grounded in the specificity of a human being (or, occasionally, an animal). Philosophy is tasked with providing the foundational cognitive tools to grasp the meaning of experience for the whole. In Hegelian terms, it unfolds the history of the concept. Yet, as George Steiner, Jacques Derrida, and other recent authors have shown, both philosophy – along with its agonistic cousin, religion -- evoke literary themes, rhetorics, and struggles. Over the past fifty years, Continental …


Politics On The Periphery: Oscar Ewing And A Special Relationship With Israel, Sarah Weaver Sep 2019

Politics On The Periphery: Oscar Ewing And A Special Relationship With Israel, Sarah Weaver

The Journal of Purdue Undergraduate Research

This essay explores the role of Oscar Ewing, an Indiana native and a graduate of Indiana University (IU), in the story of the U.S. relationship with Israel, forming even prior to Israeli statehood in 1948. The essay will show that Oscar Ewing strategically utilized his political influence and role as U.S. federal security administrator—not diplomat or member of the State Department—to impact U.S. policy toward Israel. Although Ewing is a relatively unknown name in the history of the Truman administration and Israel, his influence and contribution to the early development of the well-known special relationship between the United States and …


Model Based Analysis Of The Accuracy And Precision Of Auscultatory Blood Pressure Measurements In Patients With Atrial Fibrillation, Charles F. Babbs Sep 2019

Model Based Analysis Of The Accuracy And Precision Of Auscultatory Blood Pressure Measurements In Patients With Atrial Fibrillation, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Working Papers

Accurate measurement of blood pressure in the presence of atrial fibrillation remains an open problem. The present study combines the techniques of stochastic mathematical modeling with physiological models of the systemic circulation, cuff, and arm (1) to explore mechanisms underlying both the lack of accuracy and the lack of precision in cuff-based arterial pressure measurements during atrial fibrillation and (2) to develop strategies to correct for errors. Both the cardiovascular system and the measurement technique are described using mathematics, including both numerical techniques and analytical probability theory. Preliminary results with numerical models suggested that, despite variability, average systolic pressures tend …


Rome Vaut Bien Un Prix. An Artistic Elite In The Service Of The State: The Pensionnaires Of The Académie De France In Rome, 1666-1968, Annie Verger Sep 2019

Rome Vaut Bien Un Prix. An Artistic Elite In The Service Of The State: The Pensionnaires Of The Académie De France In Rome, 1666-1968, Annie Verger

Artl@s Bulletin

The Dictionnaire biographique des pensionnaires de l’Académie de France à Rome serves as a register for the artists sent to Italy by the French state from the time of Louis XIV in 1666 up until the abolition of the Prix de Rome concours in 1968. After this year, the selection of pensionnaires nonetheless continued this tradition in another form, and the Académie de France in Rome thus celebrated its 350th anniversary in 2016. This notion of continuity lies at the heart of the present study, which has been carried out over a number of years.

The dictionary was published …


Rome Vaut Bien Un Prix. Une Élite Artistique Au Service De L’État : Les Pensionnaires De L’Académie De France À Rome De 1666 À 1968, Annie Verger Sep 2019

Rome Vaut Bien Un Prix. Une Élite Artistique Au Service De L’État : Les Pensionnaires De L’Académie De France À Rome De 1666 À 1968, Annie Verger

Artl@s Bulletin

Le Dictionnaire biographique des pensionnaires de l’Académie de France à Rome a essentiellement pour objet le recensement du groupe des praticiens envoyés en Italie par l’État, depuis Louis XIV en 1666 jusqu’à la suppression du concours du Prix de Rome en 1968. Le recrutement des pensionnaires n’ayant pas cessé après cette date, en dépit des changements de régimes politiques, de théories esthétiques et de conditions de production, l’institution a fêté son 350ème anniversaire en 2016. Cette continuité est au principe même de l’étude engagée depuis plusieurs années. Cet article se propose de présenter les premiers résultats rendus possibles par l’étude …


La Literatura Latinoamericana Frente Al Nuevo Milenio: Idas Y Vueltas Entre Lo Local Y Lo Global, Félix Terrones Sep 2019

La Literatura Latinoamericana Frente Al Nuevo Milenio: Idas Y Vueltas Entre Lo Local Y Lo Global, Félix Terrones

Artl@s Bulletin

Abordamos la literatura latinoamericana contemporánea en el ámbito global. En este sentido, nos detenemos en tres aspectos representativos. Primero, la emergencia de grupos como McOndo (Chile) y Crack (México), los cuales plantean una concepción y una práctica diferentes de la novela. Luego, la consagración internacional de la literatura de Roberto Bolaño, un autor que, hasta cierto punto, puede ser leído como heredero de cierta tradición novelesca latinoamericana. Finalmente, abordaremos la circulación internacional de la literatura latinoamericana en los últimos años, la cual no ha dejado de interrogar el caracter tanto nacional como latinoamericano.


Une Rencontre Manquée : Confrontation, Défiance Et Stéréotypes Entre Suds Dans Milano, Fin Qui Tutto Bene De Gabriella Kuruvilla, Nicola Brarda Sep 2019

Une Rencontre Manquée : Confrontation, Défiance Et Stéréotypes Entre Suds Dans Milano, Fin Qui Tutto Bene De Gabriella Kuruvilla, Nicola Brarda

Artl@s Bulletin

Tony, a Milanese youngster of Neapolitan descent, encounters an Egyptian migrant, Samir, in a bar. Tony is drunk and Samir steals his mobile phone. This episode is narrated briefly in two chapters of Gabriella Kuruvilla’s novel Milano, fin qui tutto bene. We will try to analyze, within this misunderstanding, the ways in which the novel questions the apparent homogeneity of the notion of South, by staging the collision between two distinct Souths within the city : the South embodied by former generations of migrants originating from the Mezzogiorno, as opposed to new migrants coming from the global South.


Une Rose Des Vents Politique: The Southern Winds Of Jean Genet’S Poetic Compass, Joanne Brueton Sep 2019

Une Rose Des Vents Politique: The Southern Winds Of Jean Genet’S Poetic Compass, Joanne Brueton

Artl@s Bulletin

Iconoclastic French dissident, Jean Genet, notoriously channelled his hatred of the West as a way to discover the South. This article reads Genet’s admiration for the Palestinians as more than just a foil to the imperialist hegemony of a French homeland he reviled; but as a relation of equality that debunks the oppression of North-South dialectics. Tackling Éric Marty and Ivan Jablonka’s accusations of anti-Semitism, as well as criticisms of Orientalism, I use Genet’s 1982 essay ‘Quatre heures à Chatila’ to argue that his Palestinian texts radically re-orient the political compass where the North constructs and reifies a one-dimensional South.


The Dilemmas Of African Diaspora In The Global Art Discourse, Sabrina Moura Sep 2019

The Dilemmas Of African Diaspora In The Global Art Discourse, Sabrina Moura

Artl@s Bulletin

In this paper, I explore how the notion of African diaspora has been used as a framework for the reassessment of essentialized identity narratives in field of art history and curatorship, between the1980s and 2000s. For this, I examine the emergence of the concept in the field of cultural studies and how it served as a tool for unsettling the narratives of belonging associated to nation and ethnicity. Such contextualization provides the ground for the analysis of the dilemmas introduced by a diasporic perspective in relation to the field of African art and the local-global art discourse.


Infidelity As Reality: Re-Staging The Global South With Abbas Kiarostami’S Close-Up, Sinan Richards Sep 2019

Infidelity As Reality: Re-Staging The Global South With Abbas Kiarostami’S Close-Up, Sinan Richards

Artl@s Bulletin

In this article, we contend that, in the fields of art and visual culture, the Global South is both an elaborate lie and a radical opportunity for transformation. We investigate Kiarostami’s Close-up alongside Lacan’s psychoanalysis to show how Close-up’s filmic narrative evokes the same ‘polyvalence’ and ‘slipperiness’ as the notion of the Global South. We argue that Kiarostami’s Close-up retroactively changed Sabzian’s fate, and in so doing, Kiarostami’s re-staging actively overwrites History itself. We read the same narrative move in the concept of the Global South to suggest that the Global South adopts the Kiarostamian strategy of infidelity as reality …


Ritualisation Du Langage Et Métaphores Naturelles : Paradigmes Ou Écueils Pour Construire Un Discours Propre Au Sud ?, Cécile Chapon Sep 2019

Ritualisation Du Langage Et Métaphores Naturelles : Paradigmes Ou Écueils Pour Construire Un Discours Propre Au Sud ?, Cécile Chapon

Artl@s Bulletin

L'article envisage les conditions de possibilité d'une méthodologie propre à l'espace littéraire et artistique du Sud, à partir du cas particulier de la Caraïbe et de la double perspective du langage et de l'espace déjà élaborée dans la langue de Caliban. Les discours théoriques ou critiques qui partent de la Caraïbe créent souvent des images-concepts tantôt à partir d'un modèle linguistique hybride, tantôt à partir d'un modèle élémentaire ou géographique. L'article tâche de dégager la portée et les limites de ce double paradigme, de ritualisation du langage d'une part, et de métaphore naturelle d'autre part, pour construire un discours propre …


Parler Des Suds : Le Défi De Caliban, Béatrice Joyeux-Prunel, Roland Béhar Sep 2019

Parler Des Suds : Le Défi De Caliban, Béatrice Joyeux-Prunel, Roland Béhar

Artl@s Bulletin

Depuis les années 1990, voire 2000, une nouvelle dimension s'est imposée dans la lecture des productions culturelles contemporaines. Elle rompt avec la logique Orient-Occident puis Est/Ouest, qui avait été jusque-là celle du « monde connu ». De nombreux auteurs, artistes, écrivains et théoriciens ont mis en évidence la notion de Sud pour montrer combien la puissance du monde Nord-Atlantique reposait, depuis les premières vagues de colonisation, sur une relation inégale entre Nord et Sud, au détriment du Sud. Cette notion, jusqu’à celle de « Sud Global », irrigue de nombreux débats sans que pour autant l’on discrimine plus précisément comment …


Medical Devices Regulation In West Africa – A Situation Analysis, Abigail Ekeigwe, Kari Clase, Stephen R. Byrn, Paddy Shivanand, Zita Ekeocha Sep 2019

Medical Devices Regulation In West Africa – A Situation Analysis, Abigail Ekeigwe, Kari Clase, Stephen R. Byrn, Paddy Shivanand, Zita Ekeocha

BIRS Faculty and Staff Creative Materials

Harmonization of medical devices regulation is receiving strong global attention through the International Medical Devices Regulator’s Forum, an offshoot of the Global Harmonization Task Force on medical devices. Other current trends include the Global Medical Devices Nomenclature and the Medical Devices Single Audit Program. The medical devices regulatory field is in a state of constant innovations; technologies and new regulations and guidelines are evolving to meet the changing needs and trends. This is a veritable development because medical devices and technologies are assuming significant strategic roles in the healthcare value chain – prevention, diagnostics, treatment and cure of diseases – …


Harmonization And Laboratory Accreditation, Mercy Okezue Sep 2019

Harmonization And Laboratory Accreditation, Mercy Okezue

BIRS Faculty and Staff Creative Materials

The study aimed to investigate the impact of ISO/IEC 17025 accreditation on the quality systems of a National Medicines Regulatory Authority’s (NMRA) quality control (QC) laboratory as a means of improving the reliability of analytical reports emanating from its testing activities. The project evaluated Pre- and Post- accreditation audits for Non-Conformances (NCs) for management and technical requirements of the ISO/IEC17025:2005 Standards from a QC lab in The National Agency for Food and Drug Administration and Control (NAFDAC), Nigeria in sub-Saharan Africa. The results obtained addressed the study research questions; “does accreditation of a QC laboratory lead to improvement in the …


Human Capacity Building In Africa – The Birs Model, Kari Clase, Abigail Ekeigwe, Zita Ekeocha, Stephen R. Byrn, Paddy Shivanand Sep 2019

Human Capacity Building In Africa – The Birs Model, Kari Clase, Abigail Ekeigwe, Zita Ekeocha, Stephen R. Byrn, Paddy Shivanand

BIRS Faculty and Staff Creative Materials

Human capacity sufficiency and sustenance in regulatory science is a key factor for harmonization and an identified issue in the harmonization process specifically in Africa. The human factor is the linchpin for progress----there can be no working system without human capacity. Harmonization depends upon education that motivates and prepares individuals for leadership that subsequently fuels the profession.

This paper proposes that one of the root causes is lack of sufficient institutions in Africa providing education in regulatory sciences and introduces the Biotechnology Innovation and Regulatory Sciences (BIRS) program model. This education model began with the IPAT program and evolved into …


Sound Quality Evaluation Of Refrigerated Truck Noise, Weonchan Sung, Patricia Davies, J Stuart Bolton Sep 2019

Sound Quality Evaluation Of Refrigerated Truck Noise, Weonchan Sung, Patricia Davies, J Stuart Bolton

Publications of the Ray W. Herrick Laboratories

Noise from refrigeration units on trucks can be a problem, particularly when the trucks are parked near residences. The development of a sound evaluation method that takes into account the strength of all sound attributes affecting people’s responses, including level, is described here. Such a model, coupled with a sound prediction methodology, would be helpful to unit designers who are concerned with optimizing a unit’s acoustical performance. The analysis of human subject responses to a variety of refrigerated truck sounds (in the third of a series of three subjective tests) is described. Sixty participants rated 25 recorded and digitally modified …


More Anatomically Realistic And Quantitative Models Of Pulmonary Surfactant Action And Alveolar Stability, Charles F. Babbs Sep 2019

More Anatomically Realistic And Quantitative Models Of Pulmonary Surfactant Action And Alveolar Stability, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Working Papers

To explore basic mechanisms of action of pulmonary surfactant in preventing alveolar collapse, a first-principles analysis is done analyzing forces on the shared walls separating adjacent alveolar gas bubbles. The analysis holds for concave alveolar models with either rounded, dome-like surfaces or flat, box-like surfaces. The analysis also holds for neighboring alveoli of varying size and shape. Surfactant action is characterized by two parameters describing reduction in surface tension vs. log concentration. The resulting equations describe the net pressure tending to shift the shared position of a wall, as a function of the perturbation from a balanced initial state. In …


Memories Of Life On The Farm: Through The Lens Of Pioneer Photographer J. C. Allen, Frederick Whitford, Neal Harmeyer Sep 2019

Memories Of Life On The Farm: Through The Lens Of Pioneer Photographer J. C. Allen, Frederick Whitford, Neal Harmeyer

Purdue University Press Book Previews

John Calvin Allen, professionally known as J. C., worked as a photographer for Purdue University from 1909-1952, and operated his own photography business until his death in 1976. The J. C. Allen photographs represent an historical account of the transition from pioneer practices to scientific methodologies in agriculture and rural communities. During this major transitional period for agriculture, tractors replaced horses, hybrid corn supplanted open-pollinated corn, and soybeans changed from a novelty crop to regular rotation on most farms. During this time, purebred animals with better genetic pedigrees replaced run-of-the-mill livestock, and systematic disease prevention in cattle, swine, and poultry …


Imagining Afghanistan: Global Fiction And Film Of The 9/11 Wars, Alla Ivanchikova Sep 2019

Imagining Afghanistan: Global Fiction And Film Of The 9/11 Wars, Alla Ivanchikova

Purdue University Press Book Previews

Imagining Afghanistan examines how Afghanistan has been imagined in literary and visual texts that were published after the 9/11 attacks and the subsequent U.S.-led invasion—the era that propelled Afghanistan into the center of global media visibility. Through an analysis of fiction, graphic novels, memoirs, drama, and film, the book demonstrates that writing and screening “Afghanistan” has become a conduit for understanding our shared post-9/11 condition. “Afghanistan” serves as a lens through which contemporary cultural producers contend with the moral ambiguities of twenty-first-century humanitarianism, interpret the legacy of the Cold War, debate the role of the U.S. in the rise of …


Transforming Acquisitions And Collection Services: Perspectives On Collaboration Within And Across Libraries, Michelle Flinchbaugh, Chuck Thomas, Rob Tench, Vicki Sipe, Robin Barnard Moskal, Lynda A. Aldana, Erica A. Owusu Sep 2019

Transforming Acquisitions And Collection Services: Perspectives On Collaboration Within And Across Libraries, Michelle Flinchbaugh, Chuck Thomas, Rob Tench, Vicki Sipe, Robin Barnard Moskal, Lynda A. Aldana, Erica A. Owusu

Purdue University Press Book Previews

This book explores ways in which libraries can reach new levels of service, quality, and efficiency while minimizing cost by collaborating in acquisitions. In consortial acquisitions, a number of libraries work together, usually in an existing library consortia, to leverage size to support acquisitions in each individual library. In cross-functional acquisitions, acquisitions collaborates to support other library functions. For the library acquisitions manager, technical services manager, or the library director, awareness of different options for effective consortial and cross-functional acquisitions allows for the optimization of staff and resources to reach goals. This work presents those options in the form of …


The Role Of Using Formative Assessments In Problem-Based Learning: A Health Sciences Education Perspective, Kristi W. Kelley, Julaine M. Fowlin, Andrew A. Tawfik, Max C. Anderson Aug 2019

The Role Of Using Formative Assessments In Problem-Based Learning: A Health Sciences Education Perspective, Kristi W. Kelley, Julaine M. Fowlin, Andrew A. Tawfik, Max C. Anderson

Interdisciplinary Journal of Problem-Based Learning

Practitioners in the field of pharmacy are often confronted with ill-structured problems. Specifically, pharmacists are tasked with making patient-specific recommendations that are both safe and effective, which requires combining knowledge from the biomedical, behavioral, and pharmaceutical sciences. Given the dynamic nature of pharmacy as a profession, the field has begun to explore learning strategies that go beyond mere content coverage to strategies that better support higher-order learning outcomes. One of these approaches is problem-based learning (PBL). While studies have focused on how to support PBL to improve learning outcomes, the role of assessment is often overlooked. Further exploration is thus …


Project-Based Learning (Pjbl) In Three Southeastern Public Schools: Academic, Behavioral, And Social-Emotional Outcomes, Brooke T. Culclasure, Kyle C. Longest, Troy M. Terry Aug 2019

Project-Based Learning (Pjbl) In Three Southeastern Public Schools: Academic, Behavioral, And Social-Emotional Outcomes, Brooke T. Culclasure, Kyle C. Longest, Troy M. Terry

Interdisciplinary Journal of Problem-Based Learning

Project-based learning (PjBL) as a PK–12 instructional model is growing nationwide. PjBL is seen as a mechanism to deliver academic content in a more engaging way for students and in a way that stresses the development of skills critical to success in the 21st-century workforce. Because of its increasing popularity and the disparate breadth of research around the model, a study of PjBL in three southeastern public schools was conducted during academic years 2015–2016 and 2016–2017. This study attempted to better understand how PjBL was implemented in schools and to explore the impact of PjBL on schools, teachers, and students. …


The Impact Of Pbl As A Stem School Reform Model, Michael R. L. Odell, Teresa J. Kennedy, Eric Stocks Aug 2019

The Impact Of Pbl As A Stem School Reform Model, Michael R. L. Odell, Teresa J. Kennedy, Eric Stocks

Interdisciplinary Journal of Problem-Based Learning

Project/problem-based learning (PBL) can provide an effective model for school reform when implemented with fidelity. In the report, Rising Above the Gathering Storm, it was recommended that if the U.S. is to remain competitive in the 21st-century economy, there must be a serious effort to “enlarge the pipeline of students who are prepared to enter college and graduate with a degree in STEM” (National Academy of Sciences, National Academy of Engineering, & Institute of Medicine, 2007, p. 6). The report included the recommendation that states develop statewide specialty STEM high schools (National Academy of Sciences, National Academy of Engineering, …


Recursive Reflective Reports: Embedded Assessment In Pbl Courses For Second Language Teacher Education, Cynthia A. Caswell Aug 2019

Recursive Reflective Reports: Embedded Assessment In Pbl Courses For Second Language Teacher Education, Cynthia A. Caswell

Interdisciplinary Journal of Problem-Based Learning

This conceptual article begins with a general definition of reflection and the soft skills of PBL: collaboration, agency, and metacognition. Then it presents theoretical frameworks for reflection from second language teacher education (SLTE) (Farrell, 2015; Pennington & Richards, 2016) and illustrates six types of reflection with examples from the field of SLTE. The article features a reflective self- and peer-assessment instrument, utilized in a graduate SLTE program. The standard yet flexible template of the reflective teaching report (RTR) allows these teacher educators to interact with their students’ development in the soft skills and the content of the SLTE knowledge base. …


Performance Assessment Practice As Professional Learning, Vanessa Svihla, Tim Kubik, Tori Stevens-Shauger Aug 2019

Performance Assessment Practice As Professional Learning, Vanessa Svihla, Tim Kubik, Tori Stevens-Shauger

Interdisciplinary Journal of Problem-Based Learning

While performance assessment (PA) is well aligned to project-based learning (PjBL), teachers find it challenging to design and implement PA that is faithful to the authentic context of their projects and viewed externally as rigorous. In contrast to standardizing PA tasks — thereby diminishing authenticity — we formed a research-practice partnership (Coburn, Penuel, & Geil, 2013) that developed and used a “shell” to guide teachers in planning, implementing, and engaging in rigorous dialogues that evaluate and elevate PA practice across four PjBL schools. Drawing from analysis of artifacts and audio-recorded professional development sessions, we highlight how the effort to standardize …


Implementing And Evaluating A Course-Based Undergraduate Research Experience (Cure) At A Hispanic-Serving Institution, Michele I. Shuster Phd, Jennifer Curtiss, Timothy F. Wright, Camilla Champion, Maryam Sharifi, Judith Bosland Aug 2019

Implementing And Evaluating A Course-Based Undergraduate Research Experience (Cure) At A Hispanic-Serving Institution, Michele I. Shuster Phd, Jennifer Curtiss, Timothy F. Wright, Camilla Champion, Maryam Sharifi, Judith Bosland

Interdisciplinary Journal of Problem-Based Learning

We are examining the impact of a course-based undergraduate research experience (CURE) at a land-grant, Hispanic-serving institution in the southwestern United States. Students in our CURE completed one or two extended research projects over a single semester. Our CURE enrolled a high proportion of underrepresented minority students (70.3%), including 60.2% Hispanic students. One year after CURE completion, 31.5% of CURE students had graduated with a STEM degree, and 54.3% were enrolled in a STEM major. Pre- and postcourse surveys of indicators of persistence including scientific self-efficacy, scientific identity, valuing scientific community objectives, and intention to persist showed positive shifts. Impacts …


Collision Avoidance With Deep Reinforcement Learning, Raymond C. Li, Jun Min Ahn, Zachary Tyler Esteron, Qiyin Hong Aug 2019

Collision Avoidance With Deep Reinforcement Learning, Raymond C. Li, Jun Min Ahn, Zachary Tyler Esteron, Qiyin Hong

Purdue Undergraduate Research Conference

In the past decade, learning algorithms developed to play video games better than humans have become more common. Google’s DeepMind Technologies developed learning algorithms that could play Atari video games and also demonstrated their famous AlphaGo algorithm which outperformed professional Go players. However, little research has been done on learning algorithms developed to complete the particularly difficult single-player games. In particular, much further research could be done on developing learning algorithms for mechanically challenging games such as “bullet hell” games. We believe that agents could learn to efficiently evade obstacles utilizing deep reinforcement learning. The purpose of this study is …


Advanced Glycation End-Products Suppress Mitochondrial Function And Proliferative Capacity Of Achilles Tendon-Derived Fibroblasts, Shivan H. Patel, Feng Yue, Shannon K. Saw, Rachel Foguth, Jason R. Cannon, Jonathan H. Shannahan, Shihuan Kuang, Arman Sabbaghi, Chad C. Carroll Aug 2019

Advanced Glycation End-Products Suppress Mitochondrial Function And Proliferative Capacity Of Achilles Tendon-Derived Fibroblasts, Shivan H. Patel, Feng Yue, Shannon K. Saw, Rachel Foguth, Jason R. Cannon, Jonathan H. Shannahan, Shihuan Kuang, Arman Sabbaghi, Chad C. Carroll

Purdue University Libraries Open Access Publishing Fund

Debilitating cases of tendon pain and degeneration affect the majority of diabetic individuals. The high rate of tendon degeneration persists even when glucose levels are well controlled, suggesting that other mechanisms may drive tendon degeneration in diabetic patients. The purpose of this study was to investigate the impact of advanced glycation end-products on tendon fibroblasts to further our mechanistic understanding of the development and progression of diabetic tendinopathy. We proposed that advanced glycation end-products would induce limitations to mitochondrial function and proliferative capacity in tendon-derived fibroblasts, restricting their ability to maintain biosynthesis of tendon extracellular matrix. Using an in-vitro cell …