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Elasmobranchii Oral Microbiome Diversity Within Southeast Florida: Implications Of Shark Zoonotic And Antibiotic Resistant Pathogens Associated With Human Interactions, Amanda Finnefrock

All HCAS Student Capstones, Theses, and Dissertations

Sharks are incredibly common in the Atlantic and Gulf waters surrounding Florida. Despite the prevalent nature of these animals, little research exists on the composition of their microbial communities (or “microbiomes”). Here we aim to determine the microbial makeup of the oral environment of sharks so that we can determine if there are any bacteria of clinical significance to humans, such as being antibiotic-resistant or having elevated capability for pathogenicity. A total of 41 samples were collected from the mouths and teeth of bull, Caribbean reef, great hammerhead, lemon, nurse, and sandbar sharks caught in Southeast Florida using sterile swabs …

Geographical And Anatomical Microbiome Variation In Invasive Green Iguanas (Iguana Iguana), Amanda A. Diaz

All HCAS Student Capstones, Theses, and Dissertations

The common green iguana (Iguana iguana) was introduced to South Florida in 1965 and has since been an especially pernicious threat both environmentally and economically. This highly invasive species is also expanding in range and populations at an astonishing rate. Understanding how this reptile is able to adapt and thrive in novel environments is of imperative need in order to begin managing their disruptive populations. Notwithstanding their negative impacts and significance, the microbiome of wild populations has not yet been characterized. Here, using 16S ribosomal RNA gene sequencing, this study is the first to characterize the microbiome composition …

From Tradition To Transition: Evaluating Culinary Medicine As A Tool For Metabolic Health Among Nigerian Immigrants In The United States And The United Kingdom, Simi Oduwole M.S.

Department of Nutrition Student Projects

This scoping review examines existing publications to evaluate whether Culinary Medicine can be used as a tool for metabolic health among Nigerian immigrants in the United States and the United Kingdom. Nigeria is one of the fastest-growing populations globally, with increasing migration to high-income countries such as the United States and the United Kingdom. Evidence suggests that Nigerian immigrants experience a rise in diet-related chronic diseases, including obesity, diabetes, and cardiovascular disease, as duration of residence increases. This phenomenon is often attributed to dietary acculturation and shifts toward Westernized eating patterns. This scoping review evaluates whether culinary medicine can mitigate …

The Effect Of A Low-Glycemic Index Diet On Polycystic Ovary Syndrome Symptoms Among University-Aged Women, Angelika A. Gonzalez, Annalise M. Sankar, Noelle D. Nguyen

Department of Nutrition Student Projects

Polycystic Ovary Syndrome is an endocrine disorder among women of reproductive age and is associated with insulin resistance, menstrual irregularities, hyperandrogenism, and metabolic dysfunction. Dietary modifications targeting glycemic response have emerged as a nonpharmacologic approach for PCOS management. However, long-term randomized controlled trials targeting young adult populations remain limited.

The purpose of this study is to evaluate long-term effects of adherence to a low-glycemic index diet on the frequency and severity of PCOS symptoms among female college students ages 18-22. This 12-month randomized controlled trial will recruit participants meeting the Rotterdam criteria from university health clinics. Participants will be randomly …

Effects Of Probiotic Supplementation On Symptoms In Teenagers Ages 13-18 With Inflammatory Skin Conditions, Katelyn S. Walker, Jessica Rosen, Matilde Belfiore

Department of Nutrition Student Projects

Teenagers between the ages of 13 and 18 are particularly susceptible to inflammatory skin disorders such as acne vulgaris and atopic dermatitis, which can have a detrimental effect on their physical and mental health. Emerging evidence highlights the importance of the gut-skin axis, indicating that the makeup of the gut microbiota affects both skin health and systemic inflammation. Adolescent-specific research is still limited even though probiotic supplementation, especially Lactobacillus strains, has demonstrated anti-inflammatory effects in laboratory, animal, and small clinical studies.

The purpose of this experimental study is to determine whether oral probiotic supplementation improves inflammatory skin condition symptoms in …

The Current - Volume 36 Issue 9, Nova Southeastern University

Student Newspapers

No abstract provided.

Effectiveness Of The Mediterranean Diet For Sustained Weight Maintenance Following Glp-1 Medication Discontinuation: A Longitudinal Prospective Study, Nitya Reddy, Josephine Thomas, Julie Salam

Department of Nutrition Student Projects

Glucagon-like peptide-1 (GLP-1) receptor agonists are effective for short-term weight reduction in adults with obesity, yet weight regain is frequent after discontinued use of the medication. Identifying sustainable dietary approaches that support long-term weight maintenance is imperative. The Mediterranean diet has been associated with improving metabolic health and resistant weight control, suggesting it may be an effective strategy for the transition off GLP-1 therapy. Men and women ages 45-55 that are diagnosed with Type 2 diabetes and receiving GLP-1 receptor therapy are the targets of this study, specifically those who plan to discontinue medication within the next three months. On …

Oral Butyrate Supplementation In Patients With Als: Impact On Gut Microbiota And Disease Progression, Annabelle Keller, Kaydee Kinnett, Camaryn Barbanel, Trinity Blakeney

Department of Nutrition Student Projects

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive motor neuron loss. Emerging evidence suggests that alterations in gut microbiota—particularly reductions in butyrate-producing bacteria—may contribute to neuroinflammatory pathways involved in disease progression. Observational studies in patients with ALS and preclinical findings from transgenic mouse models demonstrate gut microbial dysbiosis, intestinal barrier dysfunction, and improved survival following butyrate supplementation, suggesting the potential role of butyrate availability in ALS pathophysiology. The present study investigates whether oral butyrate supplementation can modulate inflammatory responses, improve gut microbiota composition, and slow functional decline among patients with ALS. Participants will be recruited from …

A Comparative Analysis Of Data Privacy Laws In European Union And United States: A Need For Better Protections Of Marginalized Groups In Light Of Advances In Artificial Intelligence, Lauren Demchak

Journal of International Law and Comparative Studies

No abstract provided.

Genetic Secrets Unveiled: Unraveling Privacy Concerns In Direct-To- Consumer Genetic Testing Between The United States And The European Union, Sofia Marie Cabrera

Journal of International Law and Comparative Studies

No abstract provided.

The Effect Of The Mind Diet On Cognitive Decline In Als Patients With Frontotemporal Dementia, Riya Thomas, Reba Thomas, Eliana Gitelman

Department of Nutrition Student Projects

Amyotrophic lateral sclerosis (ALS) is a progressive disease that affects nerve cells in the brain and the spinal cord, leading to a broad range of neurological issues. Individuals with ALS experience progressive muscle weakness, dysphagia, slurred speech, and impaired movement and cognition. In addition to physical symptoms, around 15-20% of individuals with ALS also develop frontotemporal dementia (FTD). There are limited interventions to slow cognitive decline in this specific population. The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet has been associated with slower cognitive decline and reduced risk in neurodegenerative disease among older adults; however, its effects have not been …

The Effect Of Low And High-Carbohydrate Diets On Memory Performance In College Students, Samia Baugh, Zoe Zajko, Jamie Analuisa, Ivanna Jacome

Department of Nutrition Student Projects

Carbohydrates are the primary source of energy for the brain and play an important role in processes related to memory performance. The purpose of this study is to examine the impact of a low-carbohydrate diet compared to a high-carbohydrate diet on memory performance in college students aged 18–22 years. For the purposes of this study, a low-carbohydrate diet is defined as a diet providing fewer than 130 grams of carbohydrates per day, while a high-carbohydrate diet provides approximately 325 grams of carbohydrates. This population is particularly important to study because college students experience high academic demands that require strong memory …

Empirical Benchmarks For Interpreting Effect Sizes In Violent Crime Interventions, Kohta James Matsukawa Hansen

Theses and Dissertations

Criminal justice researchers apply Cohen’s (1988) benchmarks to classify effect sizes as small, medium, or large, despite these standards never being meant for broad, decontextualized use (Cohen, 1988; Gies et al., 2024; Goulet-Pelletier & Cousineau, 2018; Lakens, 2013; Milner et al., 2023). Repeatedly doing so may weaken statistical validity, distort findings, and impede effective policymaking. This study introduces the first effect size benchmarks specifically designed for violent crime interventions.

Using a quasi-meta-analysis framework, 1,605 effect sizes from 104 violent crime intervention studies from the CrimeSolutions clearinghouse were converted to Cohen’s d. Three new discrete benchmarking methods were created using a …

Photogrammetric Analysis Of Porites Lobata And Pocillopora Spp. Live Coral Cover At Devil's Crown, Galapagos Islands, Ecuador, Katherine Whitehouse, Preston Toutant

Undergraduate Student Symposium

Porites lobata and Pocillopora spp. are predominant scleractinian corals at Devil's Crown, Galápagos Islands, Ecuador that have been monitored for 48 years. Fluctuations in colony abundance and live tissue surface area of both taxa are associated with environmental variability driven by El Niño-Southern Oscillation. To better quantify colony number and live tissue cover of the two taxa, photogrammetry was utilized during a research expedition in May 2025. Two GoPro cameras were used during snorkel transects in the northwest (Porites) and northeast (Pocillopora) sectors of the shallow (2-3 m depth), elliptical submerged caldera to produce overlapping digital …

The Hidden Map Of Women's Health: Predictors And Protectors Across Our Lives, Tasfia Howlader

Undergraduate Student Symposium

Women's health has constantly been changing-from public health infrastructure to health policies, and even medical advancements. Yet, the struggles are persistent within the gaps present in women's health. The Socio-Ecological Model (SEM) explains interactions between different levels of relationships, which result in health outcomes that vary from individual factors to environmental factors. Applying the SEM to describe health disparities can help explain how the relationships an individual has influenced their health. This project serves to exemplify these different levels while discussing the tailoring of services to the needs and the importance of populations based on their experiences. Specifically, adhering to …

Parental Perceptions About Crispr And Other Biological Treatments For Fragile X Syndrome Compared With Sickle Cell Disease (2000-2025): Systematic Review Protocol, Ethan Hunter, Lukah Varghese, Mohit Belur, Prathiv Raj Ramesh Babu

Undergraduate Student Symposium

Fragile X Syndrome (FXS) is a genetic condition associated with intellectual disability, while Sickle Cell Disease (SCD) comprises inherited red blood cell disorders. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) gene-editing therapies are currently being implemented for SCD but remain experimental for FXS. Understanding caregiver perspectives on CRISPR-based therapies is crucial because families play a central role in weighing risks/benefits during treatment decision-making. Synthesizing evidence on caregiver attitudes toward CRISPR-based therapies for FXS and SCD can help determine if perceptions observed with SCD can inform expectations for FXS. This systematic review will include qualitative, quantitative, and mixed-methods studies published between …

Predicting Alzheimer's Disease Via Machine Learning Through Adni Data, Sahana Reddy

Undergraduate Student Symposium

Alzheimer's disease (AD) is a progressive neurodegenerative disease. Since the neurological pathology, including protein deposits and neurodegeneration, starts a decade before cognitive, memory, and behavioral symptoms, AD development should be predictable from physical biomarkers. This study investigates how patients' memory and cortical brain thickness at baseline can predict their likelihood of developing AD through supervised machine learning. From baseline visits, 205 participants' data were extracted from the ADNI database, all designated as healthy control in the first visit, but some converted to AD or Mild cognitive impairment (MCI) in later visits (Group 2), and some remained healthy (Group 1). The …

Creatine: More Than Just A Gym Bro Supplement? An Evidence-Based Review Of The Safety And Efficacy Of Creatine Monohydrate Supplementation, Lara Kotak

Undergraduate Student Symposium

Creatine monohydrate (CrM) is an extensively researched supplement that has been used to enhance athlete performance, muscle mass, recovery, and even improve health span beyond athletes. Despite the plethora of reasearch supporting creatine supplementation at recommended dosages, misconceptions and further questions regarding its safety and effectiveness remain. Examples of existing concerns include the potential effects of creatine on hydration levels, renal and liver function, fat mass, hair loss, muscle cramping, and fertility. Additionally, there are questions regarding the safety and effectiveness of creatine across populations of such as children, adolescents, females, older adults, and pregnant individuals. Furthermore, inquiry about the …

Time-Dependent Modulation Of Isr And Upr In Glioblastoma Stem Cells Using A Curcumin-Inspired Bis-Chalcone Analog, Abby Morrill, Carleigh Miller

Undergraduate Student Symposium

Glioblastoma (GBM) is an aggressive brain tumor driven by therapy-resistant GBM stem cells (GSCs). GSC's rely on adaptive stress pathways like the Integrated Stress Response (ISR) and Unfolded Protein Response (UPR). Curcumin modulates these pathways but has poor bioavailability. We developed curcumin-inspired bis-clacone analogs with improved potency and selectivity against GSCs and tested efficiency using a time-course study. A series of bis-chalcone analogs were synthesized and tested against three patient-derived GSC lines using MTS assay (0.1-10 μM, 72 h). A lead derivative compound compatible with carbon dot nanoparticle conjugation was synthesized and evaluated for mechanistic consistency and GSC cytotoxicity. ISR/UPR …

Marine Biodiversity Monitoring And Community Engagement On The Boulder Reefs Of Peanut Island, Sophia Oliveira, Luke Mckeon, Josie Larson, Raymond Hernandez, Triumph Perry, Lianna Rasimowicz

Undergraduate Student Symposium

Artificial boulder reefs were constructed along the shoreline of Peanut Island in Palm Beach County, Florida to enhance habitat complexity and provide a safe, accessible snorkeling experience for the island's many visitors. These nine boulder reefs support a diverse assemblage of marine organisms and offer an ideal setting for ecological monitoring. This project documents the fish, invertebrate, and coral species that utilize these structures and provides the public with accurate, easily accessible information about the organisms they may encounter while snorkeling. Monthly GoPro surveys employing a roving fish sampling technique were conducted on each reef to record new species observations …

Evaluation Of The Use Of Longitudinal Data For Depression Research And Antidepressant Drug Discovery, Rojie Ekanayake, Niousha Mousavi

Undergraduate Student Symposium

Depression is one of the most prevalent mental health disorders, affecting over 280 million people globally. Diagnosis of depression remains limited, and treatment is complicated due to the subjectivity of using psychometric scales for diagnosis. This has created a need for more objective methods for the diagnosis of depression and the assessment of the outcome of various treatment/management methods. These methods should consider a holistic approach encompassing biochemical, mental, and socioeconomic factors of patients. Longitudinal datasets, in the age of AI, offer an unprecedented opportunity for such an approach. Thus, it is hypothesized that the application of machine learning to …

Investigating Oct3-Mediated Buprenorphine Transport As A Mechanism For Salivary Accumulation And Oral Toxicity, Laasya Vemparala, Veda Pesala, Sydni Gunpath, Mehtab Singh

Undergraduate Student Symposium

In this study we prepared a 3D printed model to better understand OCT3-mediated buprenorphine transport. Buprenorphine is a high affinity partial agonist at the mu-opioid receptor (μ-OR) and main component of Suboxone. It has a unique pharmacological profile that makes it effective for treating both pain and opioid use disorder (OUD) but has been linked to oral health issues such as dry-mouth and tooth decay. The exceptionally tight binding of suboxone to μ-OR allows for sustained receptor occupancy and reduced opioid misuse potential by patients. Recent evidence suggests that the Organic Cation Transporter 3 (OCT3), a membrane transporter expressed in …

Comparative Evaluation Of Artificial Intelligence (Ai) Implications For Active Learning And Assessment In Global Stem And Health Sciences, Vinay Munlapudi

Undergraduate Student Symposium

Today's all-pervasive emergence of Artificial intelligence (AI) necessitates a comprehensive evaluation of its role in education, especially for occupational disciplines in healthcare and STEM. AI has reshaped student learning and instructors' navigation of the evolving, post COVID-19 global academic landscape. This study aimed at encapsulating evidence-based AI implications for student-centered, active learning and assessment of STEM and health-science education in developed countries versus underprivileged communities. An exploratory, scoping review of 50 recent, scholarly journal-publications was conducted over six months through diverse search engines (Pub-Med, Google Scholar, and library databases) using keywords such as "Active learning with AI" and "Assessment of …

Integrating Domain Knowledge And Machine Learning In Rice Cultivation: A Case Study Of Algeria, Sara Faruqui, Jane Krivosheev, Jenna Handal

Undergraduate Student Symposium

Research has highlighted Artificial Intelligence (AI) as a promising solution to mitigate the threat of food insecurity. Rice, a staple in the global diet, is particularly vulnerable to heat stress caused by climate change. The challenges of climate change, population growth, and increased famine risk may be alleviated through the implementation of AI models in rice cultivation. For decades, agricultural workers have faced the dilemma of needing to increase crop yields while dealing with dwindling resources and the need for more efficient practices. AI models, however, are limited by the quality and scope of the data they receive. Integrating domain …

Molecular Consequences Of Pcos-Linked Aromatase Variants: Structural Modeling And Inhibitor Docking, Kiran Sajnani, Bharath Kumar Reddy Burry, Yuktha Milukuri, Preya Patel

Undergraduate Student Symposium

Polycystic ovary syndrome (PCOS) affects approximately 10% of reproductive-age women and involves hormonal imbalance partly driven by impaired estrogen synthesis. Aromatase (CYP19A1) catalyzes conversion of testosterone and androstenedione to estrogen, but structural consequences of PCOS-associated variants remain unclear. We investifated Val161Asp (V161D), a PCOS-linked substitution that replaces a nonpolar valine with a negatively charged aspartate in a hydrophobic helical region. Using the wild-type structure (PDB 3EQM), we generated a 3D-printed model highlighting the mutation and key catalytic features (heme, substrate-binding channel, conserved monooxygenase motifs). We then produced an AlphaFold V161D model and compared it with wild type in Jmol to …

From Bedtime To Bacteria: A Sleep Extension Pilot Study Revealing Gut-Linked Pathways, Maya Totev

Undergraduate Student Symposium

While the gut contains trillions of bacteria that influence the immune, nervous, and endocrine systems, its implications in health interventions and wellness are often underappreciated. Lifestyle factors, including sleep duration and quality, influence gut microbiome composition and are linked to adverse health outcomes. While sleep extension is known to benefit health, emerging evidence suggests the gut microbiome and inflammatory pathways may help clarify these underlying mechanisms. This pilot study examined the effects of a two-week sleep extension on the gut microbiome composition in healthy adult females as part of a larger investigation of sleep, stress, and systemic inflammation. Participants completed …

The Association Between Ultra-Processed Foods And Inadequate Sleep In Us Adults From Nhanes, 2005-2018, Seema Rajper

Undergraduate Student Symposium

Ultra-processed food (UPF), rich in sugar and fat, could affect sleep quality due to inflammation and hormonal imbalance. However, the population level data is scarce, and the findings are mixed, especially in adult populations. We examined associations between UPF consumption and odds of inadequate sleep (characterized by sleep difficulty and/or inadequate sleep duration: short sleep (<7h) or long sleep (≥9 hours)) among U.S. non-pregnant, non-lactating adults using National Health and Nutrition Examination Survey (NHANES) with a 14-year span. We assessed 33,156 adults (aged ≥ 20 y) using up to two 24-hour diet recalls from the NHANES (2005 to 2018). UPF intake was calculated using the NOVA classification system, and inadequate sleep (specifically sleep difficulty, short sleep, long sleep) was ascertained from the self-reported sleep disorder survey. Odds of inadequate sleep (aORs) were compared across the quartile intakes of UPF using population weights-adjusted multivariable general logistic regression. Of the 33,156 adult participants, 34.9% had short sleep (n=11,576), 11.9% had long sleep (n-3,937), and 24.7% had sleep difficulty (n=8,199). We also found that the highest quartile of UPF, relative to the lowest quartile, is significantly associated with 23% increased odds of short sleep (aOR=1.23, 95% CI: 1.07-1.41; p=0.023), after adjusting for all covariates. The dose-response relationships between higher UPF intake and higher risk of short or long sleep were determined, respectively (both p <0.05). However, no association was found with sleep difficulty (aOR = 1.09, 95% CI: 0.95-1.26; p =0.6185). We found the dose-response relationship between higher UPF intakes and higher risk for inadequat sleep …

Microbial Signatures Of Breast Carcinogenesis: Synthesizing Evidence From Breast Tissue Microbiome Studiese, Caroline Rodriguez Chang, Revanth Madamsetty, Krishna Dasyam

Undergraduate Student Symposium

Breast cancer remains one of the most prevalent cancers worldwide, affecting approximately one in eight women in the United States. Recent advances in microbiome research have highlighted the microbiome's essential role in maintaining health and influencing disease progression. Increasing attention has been directed toward understanding how microbial communities contribute to cancer development, particularly through effects on immune function, metabolism, and cellular signaling pathways. While most existing research has examined the gut microbiome and its relationship to breast cancer focusing on the gut-breast axis, microbial translocation, and their contributions to tumor progression, there is a growing need to characterize the breast …

Energy Drinks Are Bad... Or Perhaps Not? A Comprehensive Evidence-Based Review Of Energy Drink Safety And Performance Effects, Saanvitha Rajendara

Undergraduate Student Symposium

Energy drinks rank as some of the most widely consumed functional beverages. However, they still cause controversy, confusion, and strong public opinions. Although many assume that these products are inherently harmful, a growing amount of research is constructing a different understanding. In reviewing the comprehensive analysis conducted by Dr. Jose Antonio, this presentation examines the scientific evidence behind the more common questions and misconceptions about energy drinks. These include rols of key ingredients like taurine and B-vitamins, as well as the energy drinks' influence on performance, metabolism, and overall health. The review also looks at sleep, cardiovascular function, and cognitive …

A Quantum Argument Against Zeno's Paradox Of Dichotomy, Ryan Christie-Muller

Undergraduate Student Symposium

During the pre-Socratic period, Parmenides created his radical idea of an eternal, unchanging, and motionless world. This was met with much doubt, contempt, and counterarguments that sought to disprove his statements claiming that the concept of past and future were false, and that both change and movement were impossible. Yet his student, Zeno, came after him and sought to further prove his teacher Parmenides' arguments, creating what are now talked about thousands of years later known as Zeno's paradoxes. This paper will specifically talk about Zeno's dichotomy paradox, claiming that movement cannot exist due to the inherent need to be …