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Members Of The Conserved Deda Family Are Likely Membrane Transporters And Are Required For Drug Resistance In Escherichia Coli, Sujeet Kumar, William T. Doerrler Feb 2014

Members Of The Conserved Deda Family Are Likely Membrane Transporters And Are Required For Drug Resistance In Escherichia Coli, Sujeet Kumar, William T. Doerrler

Faculty Publications

Bacterial resistance to antibiotics and biocides is an increasing public health problem. Genes encoding integral membrane proteins belonging to the DedA family are present in most bacterial genomes, including Escherichia coli. An E. coli strain lacking partially redundant DedA family genes yqjA and yghB (strain BC202) displays temperature sensitivity and cell division defects. These phenotypes can be corrected by overexpression of mdfA, anNa+-K+/H+ antiporter of the major facilitator superfamily. We show that BC202 is hypersensitive to several biocides and cationic compounds that are known substrates of several multidrug resistance transporters, including MdfA, EmrE, and AcrB. The introduction of deletions of …


Oncostatin M Is Produced In Adipose Tissue And Is Regulated In Conditions Of Obesity And Type 2 Diabetes, David Sanchez-Infantes, Ursula A. White, Carrie M. Elks, Ron F. Morrison, Jeffrey M. Gimble, Robert V. Considine, Anthony W. Ferrante, Eric Ravussin, Jacqueline M. Stephens Feb 2014

Oncostatin M Is Produced In Adipose Tissue And Is Regulated In Conditions Of Obesity And Type 2 Diabetes, David Sanchez-Infantes, Ursula A. White, Carrie M. Elks, Ron F. Morrison, Jeffrey M. Gimble, Robert V. Considine, Anthony W. Ferrante, Eric Ravussin, Jacqueline M. Stephens

Faculty Publications

Context: Adipose tissue is a highly active endocrine organ that secretes many factors that affect other tissues and whole-body metabolism. Adipocytes are responsive to several glycoprotein 130 (gp130) cytokines, some of which have been targeted as potential antiobesity therapeutics. Objective: Oncostatin M (OSM) is a gp130 family member known to inhibit adipocyte differentiation in vitro, but its effects on other adipocyte properties are not characterized. The expression of OSM in white adipose tissue (WAT) has not been evaluated in the context of obesity. Thus, our objective was to examine the expression of adipose tissue OSM in obese animals and humans. …


Virulence And Biotype Analyses Of Hessian Fly (Diptera: Cecidomyiidae) Populations From Texas, Louisiana, And Oklahoma, Sandra Garcés-Carrera, Allen Knutson, Haiyan Wang, Kristopher L. Giles, Fangneng Huang, R. Jeffrey Whitworth, C. Michael Smith, Ming Shun Chen Feb 2014

Virulence And Biotype Analyses Of Hessian Fly (Diptera: Cecidomyiidae) Populations From Texas, Louisiana, And Oklahoma, Sandra Garcés-Carrera, Allen Knutson, Haiyan Wang, Kristopher L. Giles, Fangneng Huang, R. Jeffrey Whitworth, C. Michael Smith, Ming Shun Chen

Faculty Publications

Hessian fly, Mayetiola destructor (Say, 1817), is a major pest of wheat, and is controlled mainly through deploying fly-resistant wheat cultivars. The challenge for the plant resistance approach is that virulence of Hessian fly populations in the field is dynamic, and wheat cultivars may lose resistance within 6 - 8 yr. To ensure continuous success of host plant resistance, Hessian fly populations in the field need to be constantly monitored to determine which resistance genes remain effective in different geographic regions. This study investigated five Hessian fly populations collected from Texas, Louisiana, and Oklahoma, where infestation by Hessian fly has …


Effects Of Biological Control On Long-Term Population Dynamics: Identifying Unexpected Outcomes, James R. Reilly, Bret D. Elderd Feb 2014

Effects Of Biological Control On Long-Term Population Dynamics: Identifying Unexpected Outcomes, James R. Reilly, Bret D. Elderd

Faculty Publications

Attempts to control natural systems through management have often met with success but have also led to unexpected and often undesirable outcomes. Unfortunately, the ultimate result of such management programmes may not be apparent until long after the control efforts have begun. This is particularly true for forest-defoliating species that exhibit long-period cycles such as the invasive gypsy moth Lymantria dispar, which causes widespread damage in some years but is rare in other years. We studied the effects of two commonly employed biocontrol agents on gypsy moth dynamics using a series of field-tested and empirically parameterized mathematical models, which allowed …


Fetal Baboon Sex-Specific Outcomes In Adipocyte Differentiation At 0.9 Gestation In Response To Moderate Maternal Nutrient Reduction, Y. D. Tchoukalova, R. Krishnapuram, U. A. White, D. Burk, X. Fang, M. J. Nijland, P. W. Nathanielsz Feb 2014

Fetal Baboon Sex-Specific Outcomes In Adipocyte Differentiation At 0.9 Gestation In Response To Moderate Maternal Nutrient Reduction, Y. D. Tchoukalova, R. Krishnapuram, U. A. White, D. Burk, X. Fang, M. J. Nijland, P. W. Nathanielsz

Faculty Publications

Objective:To investigate in vitro adipocyte differentiation in baboon fetuses in response to reduced maternal nutrition.Design:Cross-sectional comparison of adipocyte differentiation in normally grown fetuses and fetuses of pregnant baboons fed 70% of the control global diet from 30 days of pregnancy to term.Subjects:The subjects comprised control (CTR) fetuses (five female and five male) of mothers fed ad libitum and fetuses of mothers fed 70% of the global diet consumed by CTR (maternal nutrient reduction (MNR), five female and five male fetuses). The expression of genes/proteins involved in adipogenesis (PPARγ, FABP4 and adiponectin) and brown adipose tissue development (UCP1, TBX15 and COXIV) …


Contributions Of Adipose Tissue Architectural And Tensile Properties Toward Defining Healthy And Unhealthy Obesity, Denise E. Lackey, David H. Burk, Mohamed R. Ali, Rouzbeh Mostaedi, William H. Smith, Jiyoung Park, Philipp E. Scherer, Shundra A. Seay, Colin S. Mccoin, Paolo Bonaldo, Sean H. Adams Feb 2014

Contributions Of Adipose Tissue Architectural And Tensile Properties Toward Defining Healthy And Unhealthy Obesity, Denise E. Lackey, David H. Burk, Mohamed R. Ali, Rouzbeh Mostaedi, William H. Smith, Jiyoung Park, Philipp E. Scherer, Shundra A. Seay, Colin S. Mccoin, Paolo Bonaldo, Sean H. Adams

Faculty Publications

The extracellular matrix (ECM) plays an important role in the maintenance of white adipose tissue (WAT) architecture and function, and proper ECM remodeling is critical to support WAT malleability to accomodate changes in energy storage needs. Obesity and adipocyte hypertrophy place a strain on the ECM remodeling machinery, which may promote disordered ECM and altered tissue integrity and could promote proinflammatory and cell stress signals. To explore these questions, new methods were developed to quantify omental and subcutaneous WAT tensile strength and WAT collagen content by three-dimensional confocal imaging, using collagen VI knockout mice as a methods validation tool. These …


Genomics Of Plant Abiotic Stress Tolerance, Dong Ha Oh, Maheshi Dassanayake, Hyewon Hong, Suja George, Seol Ki Paeng, Anna Kropornika, Ray A. Bressan, Sang Yeol Lee, Dae Jin Yun, Hans J. Bohnert Jan 2014

Genomics Of Plant Abiotic Stress Tolerance, Dong Ha Oh, Maheshi Dassanayake, Hyewon Hong, Suja George, Seol Ki Paeng, Anna Kropornika, Ray A. Bressan, Sang Yeol Lee, Dae Jin Yun, Hans J. Bohnert

Faculty Publications

© 2014 by John Wiley & Sons, Inc. Genome sequences and RNA-seq data provide unparalleled views into the genetic basis that underlies plant phenotypes. This chapter outlines a paradigm shift in plant biology originating from the relative ease of generating sequences, and points to tools that have enabled global transcript analyses (RNA-seq), replacing arduous microarray hybridization experiments and laborious quantitative RT-PCR platform designs. Soon, it can be envisioned that one may replace individual transcript assays by measuring how the entire transcriptome responds globally to a manipulation or mutation. The chapter advances a position that the knowledge of genome content and …


Erratum: Peg3 Mutational Effects On Reproduction And Placenta-Specific Gene Families (Plos One (2014) 9:1 Doi: 10.1371/Annotation/8de03ec5-E62c-4135-87ee- 4928475090a8), Joomyeong Kim, Wesley D. Frey, Hongzhi He, Hana Kim, Muhammad B. Ekram, Arundhati Bakshi, Mohammad Faisal, Bambarendage P.U. Perera, An Ye, Ryoichi Teruyama Jan 2014

Erratum: Peg3 Mutational Effects On Reproduction And Placenta-Specific Gene Families (Plos One (2014) 9:1 Doi: 10.1371/Annotation/8de03ec5-E62c-4135-87ee- 4928475090a8), Joomyeong Kim, Wesley D. Frey, Hongzhi He, Hana Kim, Muhammad B. Ekram, Arundhati Bakshi, Mohammad Faisal, Bambarendage P.U. Perera, An Ye, Ryoichi Teruyama

Faculty Publications

No abstract provided.


Aphid Amino Acid Transporter Regulates Glutamine Supply To Intracellular Bacterial Symbionts, Daniel R.G. Price, Honglin Feng, James D. Baker, Selvan Bavan, Charles W. Luetje, Alex C.C. Wilson Jan 2014

Aphid Amino Acid Transporter Regulates Glutamine Supply To Intracellular Bacterial Symbionts, Daniel R.G. Price, Honglin Feng, James D. Baker, Selvan Bavan, Charles W. Luetje, Alex C.C. Wilson

Faculty Publications

Endosymbiotic associations have played a major role in evolution. However, the molecular basis for the biochemical interdependence of these associations remains poorly understood. The aphid-Buchnera endosymbiosis provides a powerful system to elucidate how these symbioses are regulated. In aphids, the supply of essential amino acids depends on an ancient nutritional symbiotic association with the gamma-proteobacterium Buchnera aphidicola. Buchnera cells are densely packed in specialized aphid bacteriocyte cells. Here we confirm that five putative amino acid transporters are highly expressed and/or highly enriched in Acyrthosiphon pisum bacteriocyte tissues. When expressed in Xenopus laevis oocytes, two bacteriocyte amino acid transporters displayed significant …


Species Coexistence And The Dynamics Of Phenotypic Evolution In Adaptive Radiation, Joseph A. Tobias, Charlie K. Cornwallis, Elizabeth P. Derryberry, Santiago Claramunt, Robb T. Brumfield, Nathalie Seddon Jan 2014

Species Coexistence And The Dynamics Of Phenotypic Evolution In Adaptive Radiation, Joseph A. Tobias, Charlie K. Cornwallis, Elizabeth P. Derryberry, Santiago Claramunt, Robb T. Brumfield, Nathalie Seddon

Faculty Publications

Interactions between species can promote evolutionary divergence of ecological traits and social signals, a process widely assumed to generate species differences in adaptive radiation. However, an alternative view is that lineages typically interact when relatively old, by which time selection for divergence is weak and potentially exceeded by convergent selection acting on traits mediating interspecific competition. Few studies have tested these contrasting predictions across large radiations, or by controlling for evolutionary time. Thus the role of species interactions in driving broad-scale patterns of trait divergence is unclear. Here we use phylogenetic estimates of divergence times to show that increased trait …


Morphogenesis And Propagation Of Complex Cracks Induced By Thermal Shocks, Blaise Bourdin, Jean Jacques Marigo, Corrado Maurini, Paul Sicsic Jan 2014

Morphogenesis And Propagation Of Complex Cracks Induced By Thermal Shocks, Blaise Bourdin, Jean Jacques Marigo, Corrado Maurini, Paul Sicsic

Faculty Publications

We study the genesis and the selective propagation of complex crack networks induced by thermal shock or drying of brittle materials. We use a quasistatic gradient damage model to perform large-scale numerical simulations showing that the propagation of fully developed cracks follows Griffith criterion and depends only on the fracture toughness, while crack morphogenesis is driven by the material's internal length. Our numerical simulations feature networks of parallel cracks and selective arrest in two dimensions and hexagonal columnar joints in three dimensions, without any hypotheses on cracks geometry, and are in good agreement with available experimental results. © 2014 American …


The Economics Of Dead Zones: Causes, Impacts, Policy Challenges, And A Model Of The Gulf Of Mexico Hypoxic Zone, S S. Rabotyagov, C. L. Kling, P. W. Gassman, Nancy N. Rabalais, R. Euigene Turner Jan 2014

The Economics Of Dead Zones: Causes, Impacts, Policy Challenges, And A Model Of The Gulf Of Mexico Hypoxic Zone, S S. Rabotyagov, C. L. Kling, P. W. Gassman, Nancy N. Rabalais, R. Euigene Turner

Faculty Publications

This article reviews and analyzes the issues related to worldwide hypoxic zones and the range of economic questions sorely in need of answers. We begin by describing the extent and causes of hypoxic zones worldwide, followed by a review of the evidence concerning ecological effects of hypoxic zones and their impacts on ecosystem services. We describe what is known about abatement options and cost-effective policy design, and then focus on the large seasonally recurring hypoxic zone in the Gulf of Mexico. We offer a simple econometric model to estimate the relationship between pollutants (nutrients) and the size of the hypoxic …


Discussion Of: Olea, Ra And Coleman, Jl, Jr., 2014. A Synoptic Examination Of Causes Of Land Loss In Southern Louisiana As Related To The Exploitation Of Subsurface Geological Resources. Journal Of Coastal Research, 30(5), 1025-1044., R. Eugene Turner Jan 2014

Discussion Of: Olea, Ra And Coleman, Jl, Jr., 2014. A Synoptic Examination Of Causes Of Land Loss In Southern Louisiana As Related To The Exploitation Of Subsurface Geological Resources. Journal Of Coastal Research, 30(5), 1025-1044., R. Eugene Turner

Faculty Publications

I comment on Olea and Coleman's (2014) conclusion that subsidence was the primary cause of the dramatic rise in Louisiana's coastal land losses in the last 100 years. The focus on subsidence combined with the omission of context for factors not related to subsidence (e.g., dredged canals), leaves the reader with the incorrect conclusion that anthropogenic factors observed to date are insignificant, and that coastal wetland losses are only driven by subsidence. I address this omission by discussing two points about anthropogenic influences: (1) dredged canals and (2) changes in sediment load from the watershed and its distribution. They omit …


Eutrophication-Driven Deoxygenation In The Coastal Ocean, N N. Rabalais, W J. Cai, J Carstensen, D J. Conley, N N. Rabalais, X P. Hu, Z Quinones-Rivera, R Rosenberg, C P. Slomp, R. Eugene Turner, M Voss, B Wissel, J Zhang Jan 2014

Eutrophication-Driven Deoxygenation In The Coastal Ocean, N N. Rabalais, W J. Cai, J Carstensen, D J. Conley, N N. Rabalais, X P. Hu, Z Quinones-Rivera, R Rosenberg, C P. Slomp, R. Eugene Turner, M Voss, B Wissel, J Zhang

Faculty Publications

Human activities, especially increased nutrient loads that set in motion a cascading chain of events related to eutrophication, accelerate development of hypoxia (lower oxygen concentration) in many areas of the world's coastal ocean. Climate changes and extreme weather events may modify hypoxia. Organismal and fisheries effects are at the heart of the coastal hypoxia issue, but more subtle regime shifts and trophic interactions are also cause for concern. The chemical milieu associated with declining dissolved oxygen concentrations affects the biogeochemical cycling of oxygen, carbon, nitrogen, phosphorus, silica, trace metals, and sulfide as observed in water column processes, shifts in sediment …


Absorption And Fluorescence Properties Of Chromophoric Dissolved Organic Matter Of The Eastern Bering Sea In The Summer With Special Reference To The Influence Of A Cold Pool, E.J. D'Sa, J.I. Goes, H. Gomes, C. Mouw Jan 2014

Absorption And Fluorescence Properties Of Chromophoric Dissolved Organic Matter Of The Eastern Bering Sea In The Summer With Special Reference To The Influence Of A Cold Pool, E.J. D'Sa, J.I. Goes, H. Gomes, C. Mouw

Faculty Publications

No abstract provided.


Assessment Of Chlorophyll Variability Along The Louisiana Coast Using Multi-Satellite Data, E.J. D'Sa Jan 2014

Assessment Of Chlorophyll Variability Along The Louisiana Coast Using Multi-Satellite Data, E.J. D'Sa

Faculty Publications

No abstract provided.


A Reversal Of Fortunes: Climate Change 'Winners' And 'Losers' In Antarctic Peninsula Penguins, G.V. Clucas, M.J. Dunn, G. Dyke, S.D. Emslie, R. Naveen, M.J. Polito, O.G. Pybus, A.D. Rogers, T. Hart Jan 2014

A Reversal Of Fortunes: Climate Change 'Winners' And 'Losers' In Antarctic Peninsula Penguins, G.V. Clucas, M.J. Dunn, G. Dyke, S.D. Emslie, R. Naveen, M.J. Polito, O.G. Pybus, A.D. Rogers, T. Hart

Faculty Publications

No abstract provided.


Mangrove Swamps: Sentinel Ecosystem In Front Of The Climatic Change, Gulf Of Mexico, Alejandro Yáñez-Arancibia, John W. Day, Robert R. Twilley, Richard H. Day Jan 2014

Mangrove Swamps: Sentinel Ecosystem In Front Of The Climatic Change, Gulf Of Mexico, Alejandro Yáñez-Arancibia, John W. Day, Robert R. Twilley, Richard H. Day

Faculty Publications

Considering the challenge that the economic, social and ecological systems face-in order to know and mitigate the global climate change-, evidences of the functional structure of mangroves ecological system are presented revisiting the hypothesis presented by Yáñez-Arancibia et al. (1998), and revised latter by Yáñez-Arancibia et al. (2010): “the mangroves as a critical forest habitat of the coastal zone present accommodation responses to the environmental variability that induces global change playing an structural and functional role in the stability of the coastline, the persistence of habitats and biodiversity, the metabolism of the ecosystem, reducing risks and uncertainty for the sustainable …


Comparative Study Of Three Two-Stage Hybrid Ecological Wastewater Treatment Systems For Producing High Nutrient, Reclaimed Water For Irrigation Reuse In Developing Countries, Florentina Zurita, John R. White Jan 2014

Comparative Study Of Three Two-Stage Hybrid Ecological Wastewater Treatment Systems For Producing High Nutrient, Reclaimed Water For Irrigation Reuse In Developing Countries, Florentina Zurita, John R. White

Faculty Publications

In this study, three different two-stage hybrid ecological wastewater treatment systems (HEWTS) with combinations of horizontal flow (HF) constructed wetlands (CWs), vertical flow (VF) CWs and stabilization ponds (SP) were evaluated for the removal of Organic-N, NH4+, NO3-, Total N, Total P, Total Coliforms (TCol) and Escherichia Coli, BOD, COD and TSS. The overall goal of the study was novel in comparison to most other studies in that we sought to evaluate and compare the efficiency of the three HEWTSs for water quality improvements, while minimizing nutrient removal from the wastewater in order to generate high …


Assessing Early Looks At Biological Responses To The Macondo Event, N. Rabalais Jan 2014

Assessing Early Looks At Biological Responses To The Macondo Event, N. Rabalais

Faculty Publications

No abstract provided.


Concentrations And Sources Of Polycyclic Aromatic Hydrocarbons In Surface Coastal Sediments Of The Northern Gulf Of Mexico, Zucheng Wang, Zhanfei Liu, Kehui Xu, Lawrence M. Mayer, Zulin Zhang, Alexander S. Kolker, Wei Wu Jan 2014

Concentrations And Sources Of Polycyclic Aromatic Hydrocarbons In Surface Coastal Sediments Of The Northern Gulf Of Mexico, Zucheng Wang, Zhanfei Liu, Kehui Xu, Lawrence M. Mayer, Zulin Zhang, Alexander S. Kolker, Wei Wu

Faculty Publications

No abstract provided.


Distinct Responses Of Gulf Of Mexico Phytoplankton Communities To Crude Oil And The Dispersant Corexit® Ec9500a Under Different Nutrient Regimes, Koray Ozhan, Sibel Bargu Jan 2014

Distinct Responses Of Gulf Of Mexico Phytoplankton Communities To Crude Oil And The Dispersant Corexit® Ec9500a Under Different Nutrient Regimes, Koray Ozhan, Sibel Bargu

Faculty Publications

This study examines the potential effects of exposure to South Louisiana sweet crude oil (LSC), Corexit® EC9500A, and dispersed oil on enclosed phytoplankton communities under different nutrient regimes. Three distinct microcosm experiments were conducted for 10 days to assess changes to the structure of natural communities from the Gulf of Mexico as quantified by temporal changes in the biomasses of different phytoplankton groups. Concentration of NO3, Si and PO4 were 0.83, 0.99 and 0.09 μM for the unenriched treatments and 14.07, 13.01 and 0.94 μM for the enriched treatments, respectively. Overall, the contaminants LSC and Corexit® EC9500A led to a …


Gumbo Yearbook, Class Of 2014, Louisiana State University And Agricultural And Mechanical College Jan 2014

Gumbo Yearbook, Class Of 2014, Louisiana State University And Agricultural And Mechanical College

Gumbo Yearbook

The Gumbo yearbook chronicles the entire academic year at LSU. In words and especially photos, the Gumbo shows the people, places, and events that make each year unique. In addition to formal portraits of schools and departments, the book contains hundreds of snapshots of students with their friends and dozens of pages showcasing organizations.


Chronic Exposure To A Low Dose Of Ingested Petroleum Disrupts Corticosterone Receptor Signalling In A Tissue-Specific Manner In The House Sparrow (Passer Domesticus), Christine R. Lattin, L. Michael Romero Jan 2014

Chronic Exposure To A Low Dose Of Ingested Petroleum Disrupts Corticosterone Receptor Signalling In A Tissue-Specific Manner In The House Sparrow (Passer Domesticus), Christine R. Lattin, L. Michael Romero

Faculty Publications

© The Author 2014. Stress-induced concentrations of glucocorticoid hormones (including corticosterone, CORT) can be suppressed by chronic exposure to a low dose of ingested petroleum. However, endocrine-disrupting chemicals could interfere with CORT signalling beyond the disruption of hormone titres, including effects on receptors in different target tissues. In this study, we examined the effects of 6 weeks of exposure to a petroleum-laced diet (1% oil weight:food weight) on tissue mass and intracellular CORT receptors in liver, fat, muscle and kidney (metabolic tissues), spleen (an immune tissue) and testes (a reproductive tissue). In the laboratory, male house sparrows were fed either …


Role Of Adipose Tissue In The Pathogenesis And Treatment Of Metabolic Syndrome, David Sanchez-Infantes, Jacqueline M. Stephens Jan 2014

Role Of Adipose Tissue In The Pathogenesis And Treatment Of Metabolic Syndrome, David Sanchez-Infantes, Jacqueline M. Stephens

Faculty Publications

© Springer International Publishing Switzerland 2014. Adipocytes are highly specialized cells that play a major role in energy homeostasis in vertebrate organisms. Excess adipocyte size or number is a hallmark of obesity, which is currently a global epidemic. Obesity is not only the primary disease of fat cells, but also a major risk factor for the development of Type 2 diabetes, cardiovascular disease, hypertension, and metabolic syndrome (MetS). Today, adipocytes and adipose tissue are no longer considered passive participants in metabolic pathways. In addition to storing lipid, adipocytes are highly insulin sensitive cells that have important endocrine functions. Altering any …


Natural Selection Canalizes Expression Variation Of Environmentally Induced Plasticity-Enabling Genes, Joseph R. Shaw, Thomas H. Hampton, Benjamin L. King, Andrew Whitehead, Fernando Galvez, Robert H. Gross, Nathan Keith, Emily Notch, Dawoon Jung, Stephen P. Glaholt, Celia Y. Chen, John K. Colbourne, Bruce A. Stanton Jan 2014

Natural Selection Canalizes Expression Variation Of Environmentally Induced Plasticity-Enabling Genes, Joseph R. Shaw, Thomas H. Hampton, Benjamin L. King, Andrew Whitehead, Fernando Galvez, Robert H. Gross, Nathan Keith, Emily Notch, Dawoon Jung, Stephen P. Glaholt, Celia Y. Chen, John K. Colbourne, Bruce A. Stanton

Faculty Publications

© 2014 The Author. Many organisms survive fluctuating and extreme environmental conditions by manifesting multiple distinct phenotypes during adulthood by means of developmental processes that enable phenotypic plasticity. We report on the discovery of putative plasticity-enabling genes that are involved in transforming the gill of the euryhaline teleost fish, Fundulus heteroclitus, from its freshwater to its seawater gill-type, a process that alters both morphology and function. Gene expression that normally enables osmotic plasticity is inhibited by arsenic. Gene sets defined by antagonistic interactions between arsenic and salinity show reduced transcriptional variation among individual fish, suggesting unusually accurate and precise regulatory …


Combustion By-Products And Their Health Effects - Combustion Engineering And Global Health In The 21st Century: Issues And Challenges, Slawo Lomnicki, Brian Gullett, Tobias Stöger, Ian Kennedy, Jim Diaz, Tammy R. Dugas, Kurt Varner, Danielle J. Carlin, Barry Dellinger, Stephania A. Cormier Jan 2014

Combustion By-Products And Their Health Effects - Combustion Engineering And Global Health In The 21st Century: Issues And Challenges, Slawo Lomnicki, Brian Gullett, Tobias Stöger, Ian Kennedy, Jim Diaz, Tammy R. Dugas, Kurt Varner, Danielle J. Carlin, Barry Dellinger, Stephania A. Cormier

Faculty Publications

The 13th International Congress on Combustion By-Products and their Health Effects was held in New Orleans, Louisiana from May 15 to 18, 2013. The congress, sponsored by the Superfund Research Program, National Institute of Environmental Health Sciences, and National Science Foundation, brought together international academic and government researchers, engineers, scientists, and policymakers. With industrial growth, increased power needs and generation and coal consumption and their concomitant emissions, pernicious health effects associated with exposures to these emissions are on the rise. This congress provides a unique platform for interdisciplinary exchange and discussion of these topics. The formation, conversion, control, and health …


Deficiency Of The Two-Pore-Domain Potassium Channel Trek-1 Promotes Hyperoxia-Induced Lung Injury, Andreas Schwingshackl, Bin Teng, Patrudu Makena, Manik Ghosh, Scott E. Sinclair, Charlean Luellen, Louisa Balasz, Cynthia Rovnaghi, Robert M. Bryan, Eric E. Lloyd, Elizabeth Fitzpatrick, Jordy S. Saravia, Stephania A. Cormier, Christopher M. Waters Jan 2014

Deficiency Of The Two-Pore-Domain Potassium Channel Trek-1 Promotes Hyperoxia-Induced Lung Injury, Andreas Schwingshackl, Bin Teng, Patrudu Makena, Manik Ghosh, Scott E. Sinclair, Charlean Luellen, Louisa Balasz, Cynthia Rovnaghi, Robert M. Bryan, Eric E. Lloyd, Elizabeth Fitzpatrick, Jordy S. Saravia, Stephania A. Cormier, Christopher M. Waters

Faculty Publications

Copyright © 2014 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins. Objectives: We previously reported the expression of the twoporedomain K+ channel TREK-1 in lung epithelial cells and proposed a role for this channel in the regulation of alveolar epithelial cytokine secretion. In this study, we focused on investigating the role of TREK-1 in vivo in the development of hyperoxia-induced lung injury. Design: Laboratory animal experiments. Setting: University research laboratory. Subjects: Wild-type and TREK-1-deficient mice. Interventions: Mice were anesthetized and exposed to 1) room air, no mechanical ventilation, 2) 95% hyperoxia for 24 hours, and 3) …


Response Of Native Insect Communities To Invasive Plants, T. Martijn Bezemer, Jeffrey A. Harvey, James T. Cronin Jan 2014

Response Of Native Insect Communities To Invasive Plants, T. Martijn Bezemer, Jeffrey A. Harvey, James T. Cronin

Faculty Publications

Invasive plants can disrupt a range of trophic interactions in native communities. As a novel resource they can affect the performance of native insect herbivores and their natural enemies such as parasitoids and predators, and this can lead to host shifts of these herbivores and natural enemies. Through the release of volatile compounds, and by changing the chemical complexity of the habitat, invasive plants can also affect the behavior of native insects such as herbivores, parasitoids, and pollinators. Studies that compare insects on related native and invasive plants in invaded habitats show that the abundance of insect herbivores is often …


Relative Importance Of Host Environment, Transmission Potential And Host Phylogeny To The Structure Of Parasite Metacommunities, Tad Dallas, Steven J. Presley Jan 2014

Relative Importance Of Host Environment, Transmission Potential And Host Phylogeny To The Structure Of Parasite Metacommunities, Tad Dallas, Steven J. Presley

Faculty Publications

Identification of mechanisms that shape parasite community and metacommunity structures have important implications to host health, disease transmission, and the understanding of community assembly in general. Using a long-term dataset on parasites from desert rodents, we examined the relative contributions of host traits that represent important aspects of parasite environment, transmission probability between host species, and host phylogeny to the structure of a parasite metacommunity as well as for taxonomically restricted parasite metacommunities (coccidians, ectoparasites and helminths). This was done using a combination of metacommunity analysis and variance partitioning based on canonical correspondence analysis. Coccidian and ectoparasite metacommunities did not …