Digital Commons Network^™

Caldwell Adaptive Plasma Conditioning & Sensing System (Capcs V4.0), Michael Victor Caldwell Mr.

Defensive Publications Series

The Caldwell Adaptive Plasma Conditioning & Sensing System (CAPCS v4.0) is a next‑generation, fully autonomous microfluidic biosensing platform designed for real‑world plasma analysis under variable biological, thermal, and mechanical conditions. CAPCS integrates differential quartz crystal microbalance (QCM) sensing, surface acoustic wave (SAW) focusing, adaptive closed‑loop control, predictive fouling detection, dynamic thermal stabilization, and hybrid inertial–acoustic cell removal into a single disposable cartridge.

Unlike traditional biosensor concepts that rely on static assumptions, CAPCS v4.0 continuously adapts to fouling, drift, clogging, viscosity changes, hematocrit variability, and thermal fluctuations. Every major failure mode is paired with a dedicated countermeasure. The system uses dual‑QCM …

The Whisper Web: A Mail Intelligence Framework For Semantic Coordination In Communication Systems, Johny Manuel-Devadoss, Joanna Johnson, Jayden Jack Johnson, Deepthi Prasad

Defensive Publications Series

This paper introduces The Whisper Web, a communication intelligence framework designed for post-static digital correspondence ecosystems operating under conditions of planetary-scale coordination complexity. Unlike conventional email systems that treat messages as isolated immutable payloads exchanged between endpoints, the Whisper Web reconceptualizes communication as a continuously evolving semantic biosphere composed of dynamic probabilistic entities known as Whisper Units. Each Whisper Unit functions as a compressed socio-semantic organism capable of propagating influence through adaptive trust topologies, negotiation-energy fields, obligation gradients, institutional resonance maps, and multi-agent predictive coordination networks.

The proposed framework abandons the traditional paradigms of inboxes, message queues, folders, labels, and …

Robert, Powers; Unl Chemistry; Nmr-Assisted Drug Discovery, Mark Griep, Robert Powers

Department of Chemistry: Faculty Interviews

Dr. Robert Powers became a chemistry professor at the University of Nebraska-Lincoln in 2003 and is about to retire after 23 years. Prior to UNL, Bob was a drug discovery researcher for 11 years at American Cyanamid, which eventually became Wyeth and is now part of Pfizer. Bob was born in Jersey City, New Jersey. Something in his youth must have sparked an interest in chemistry because he earned a bachelor's in that subject from Rutgers University in New Brunswick. Then he traveled 1200 miles west to Purdue University in Indiana where he earned his doctorate. Next, he did postdoctoral …

Patterns And Drivers Of Cladocera Community Structure In The Black Sea, Elena Bisinicu, Luminita Lazar

Turkish Journal of Zoology

Cladoceran community dynamics were examined in the Romanian sector of the Black Sea during the warm seasons of 2013– 2020, using Marine Reporting  Units (MRUs) to evaluate spatial heterogeneity across transitional, coastal, and  marine waters. Analyses of density, biomass, mean individual biomass (MIB), and  species composition revealed interannual fluctuations superimposed on strong  nearshore–offshore gradients, with higher values in transitional and coastal MRUs.  The assemblage was consistently dominated by Pleopis polyphemoides and Penilia  avirostris, which together accounted for most of the total abundance and biomass.  Multivariate analysis identified significant differences in taxonomic composition  across MRUs and years, while correlation analyses highlighted …

Cover And Contents

Turkish Journal of Zoology

No abstract provided.

Endemism Patterns Of Leaf Beetles (Coleoptera: Chrysomelidae) In Türkiye, İsmai̇l Şen, Ali̇ Gök

Turkish Journal of Zoology

In this study, the distribution of endemic leaf beetles in Türkiye was analyzed  holistically at the provincial scale using species richness (ENR), corrected weighted  endemism (CWE), and range-restricted endemism (RRE) indices. A total of 95  endemic taxa were found in Türkiye and these taxa exhibited significant spatial  heterogeneity in terms of richness and extent of distribution. The Western and  Central Taurus Mountains and the Eastern Black Sea Region were found to be the  main centers of endemism, with high densities of narrowly distributed and  geographically restricted species. These patterns clearly demonstrate that key  biogeographic factors, such as steep elevation gradients, …

The Effect Of Spatial Scale Of Habitat On Abundance Of Roe Deer (Capreolus Pygargus) And Water Deer (Hydropotes Inermis Argyropus) During Summer In South Korea, Naeyoung Kim, Hyejin Kim, Hyoun-Gi Cha, Hyun-Su Hwang

Turkish Journal of Zoology

Understanding species-specific habitat preferences provides essential ecological  information about interactions among habitat components. In South Korea, roe deer  (Capreolus pygargus) and water deer (Hydropotes inermis argyropus) are the  dominant large herbivorous mammals of the family Cervidae. The increasing populations of these species have led to ecological and economic  challenges. Therefore, we investigated the effects of spatial scale characteristics on  the habitat preferences of roe deer and water deer. From June to August each year  between 2021 and 2023, we calculated the relative abundance index (RAI) using  camera-trap data and analyzed patch characteristics in the study area using remote  sensing techniques, …

Balancing Civil Liberties And Civil Rights, Adam Opp

Journal of Statesmanship & Public Policy: Briefs and Commentaries

The Framers stressed the importance of civil liberties when drafting the United States Constitution to guarantee the freedoms of individuals. However, for decades, there has been an increased focus on civil rights to protect individuals from discrimination and ensure their equality under the law. The question becomes how civil liberties and civil rights intersect, and whether this intersection is always positive, or if advocating for civil rights can come at the expense of civil liberties. This paper will discuss civil liberties and civil rights, examine how policy processes impact civil rights, and address concerns about the grave consequences for the …

The Impact Of Tgfβ Conditioning And Socs3 Expression On Cytokine Signal Transduction And Inflammatory Gene Expression In Fibroblasts, Morgan Anderson-Crannage

NYMC Student Theses and Dissertations

Inflammation is a major driver in many aspects of recessive dystrophic epidermolysis bullosa (RDEB) pathology, including impaired wound healing, fibrosis, and potentially cutaneous squamous cell carcinoma development. Fibroblasts, as key stromal cells in the dermis, are responsible for orchestrating inflammatory responses through the secretion of cytokines and chemokines upon stimulation with IL-1α or IL-6. Suppressor of Cytokine Signaling 3 (SOCS3) functions as a negative feedback regulator of cytokine signaling and has emerged as a key modulator of inflammatory responses in immune cells and fibroblasts. Transforming Growth Factor Beta (TGFβ), a known driver of fibrosis in RDEB, has been implicated in …

Techno-Economic Assessment And Life Cycle Analysis Of Electrocatalytic Reduction Of Co2 To Ethanol., Omotolani Elizabeth Oduyebo

LSU Master's Theses

This study presents a techno-economic analysis (TEA) and life cycle assessment (LCA) of the electrocatalytic reduction of CO₂ to ethanol, a multi-carbon (C₂) product with significant market value. Prior TEA studies have relied on simplified lump-sum separation cost estimates, and prior LCA studies have rarely examined the combined effect of CO₂ source and electricity supply on carbon intensity gaps that this work addresses through process-simulation-grounded analysis. An Aspen Plus process simulation was developed for an anion-exchange membrane (AEM) electrolyzer system coupled with an extractive distillation separation train using ethylene glycol as the entrainer, achieving 99.9 wt.% ethanol purity …

The Ecotoxicological Impact Of Polystyrene On Lissachatina Fulica: A Study Of Growth,  Pedal Mucus Histological Changes, And Protein Mucus Analysis, Atin Supiyani, Wasmen Manalu, Lina Noviyanti Sutardi, Mawar Subangkit, Andriyanto Andriyanto

Turkish Journal of Zoology

Lissachatina fulica mucin can be used as a nutraceutical agent depending on the  quality of their feed. Polystyrene (PS) waste harms soil and plants consumed by  snails, potentially affecting the quality of mucin production. This study investigated  the impact of PS on growth and mucus-producing cell characteristics as well as the  network pharmacology of mucin protein components. Fifty 5–6 cm L. fulica snails  (20–24 g) were fed organic waste (OW) and organic waste with PS (OWPS). After 28  days of ad libitum access to food, the snails’ mucus, meat, and shells were  collected and weighed. Tissue samples from the anterior …

Imbalance In Wnt: Retinoic Acid Signaling Dysregulates Hox Gene Expression: Implications For Cancer Stem Cell Heterogeneity And Crc Patient Survival, Brian Osmond, Chi Zhang, Pascal K. Kataboh, Caroline O. B. Facey, Lynn M. Opdenaker, Bruce M. Boman

Department of Pharmacology and Experimental Therapeutics Faculty Papers

How HOX transcription factors play a role in the stem cell (SC) origin of cancer is unclear. Our goal is to determine how dysregulation of HOX gene expression promotes colorectal cancer (CRC) development through aberrant SC regulatory mechanisms. We investigated retinoic acid (RA) and WNT signaling because they regulate HOX expression and both pathways are dysregulated in cancer. Previously, we reported WNT and RA pathways are functionally linked, and in CRC, APC mutation generates a WNT:RA imbalance leading to incomplete differentiation and SC overpopulation. We hypothesize that aberrant WNT- and RA-signaling dysregulates HOX expression that contributes to the SC origin …

Beyond The Ban: Chhaupadi Abolition And The Governance Of Menstrual Autonomy In Western Nepal, Nikita Paudel

Master in Public Policy Theses

This thesis examines how two decades of efforts to abolish chhaupadi have shaped the everyday conditions under which women and girls experience menstruation in western Nepal. Chhaupadi, commonly understood as menstrual seclusion, has been addressed through Supreme Court directives, national policy, criminal law, municipal implementation instruments, hut demolition campaigns, public health programming, and rights-based advocacy. Yet the practice has persisted, adapted, and in some cases moved into less visible spaces. Rather than treating this as a simple gap between law and practice, this thesis asks how abolition efforts themselves have become part of the regulatory regime through which menstruation is …

Dna Strand Breaks By Small Molecules: From Genomic Hazard To Therapeutic Strategy, Clerin John

Honors Scholar Theses

DNA strand breaks are among the most critical forms of genomic damage, arising from endogenous metabolic activity, environmental stress, radiation, and diverse chemical agents. Single-strand breaks and double-strand breaks contribute to genome instability, mutagenesis, carcinogenesis, and neurodegenerative disorders. Cells rely on DNA repair pathways to detect these breaks and initiate repair. In this review, we conducted a comprehensive literature review to systematically compile and examine the mechanisms underlying small-molecule-induced DNA strand breaks. This review highlights the underlying mechanisms by which these molecules interact with DNA and trigger damage. We further discussed the current methods used for detection and quantification of …

Models, Agency, And Expectations: A Mixed-Methods Study Of How Character Develops In Middle School, Aaron J. Schwindt

LSU Doctoral Dissertations

This explanatory sequential mixed-methods study investigated how character develops among middle school students at an international school recognized as a "National School of Character." Despite significant investment in character education (CE), a lack of formal evaluation exists, particularly regarding the process of development during the critical middle school years, a period of intense neurological and social change. Grounded in Bandura's Social Cognitive Theory (SCT), this study aimed to (1) understand how character develops, (2) compare development before and after program enhancements, and (3) assess the program's impact on discipline. Phase 1 collected Character Growth Index (CGI) survey data from students …

Serum-Derived Albumin As A Cryoprotective Agent For The Long-Term Storage Of Red Blood Cells: A Preliminary Examination, Thomas Bailey-Schmidt, Christine V Saunders, Chloë E George, Thomas G Scorer, Lynn M R Mccallum, Tracey E Madgett

School of Biomedical Sciences

BACKGROUND: Cryopreservation extends the shelf life of red blood cells (RBC) from weeks to years, offering major advantages for blood banking logistics, especially in remote environments. However, current glycerol-based methods, though effective, are limited in scope due to complex post-thaw washing and incompatibility with routine clinical workflows. This study evaluated plasma-derived albumin as a potential alternative cryoprotective agent (CPA) for human RBC.

STUDY DESIGN AND METHODS: Donor-derived RBC were suspended in 25% w/v bovine serum albumin (BSA) prepared in various diluents and tested for biocompatibility and cryoprotective efficacy under rapid freezing (immersion in liquid nitrogen) and gradual freezing with storage …

Pfas Toxicity: What’S True, What’S Not, And What Really Matters, Jamie C. Dewitt, Ian T. Cousins, Gretta Goldenman, Dorte Herzke, Rainer Lohmann, Mark Miller, Carla A. Ng, Martin Scheringer, Xenia Trier, Zhanyun Wang

Graduate School of Oceanography Faculty Publications

A substantial body of evidence exists demonstrating that exposure to per- and polyfluoroalkyl substances (PFASs) poses a risk to human health. Data from epidemiological studies of those exposed occupationally or environmentally demonstrate adverse health risks, and these health effects are concordant with data from toxicological studies. Systematic reviews, conducted by agencies, organizations, and independent scientists that synthesize and integrate these data streams, have concluded that a range of health risks arise from PFAS exposure, including different types of cancer, especially kidney and testicular cancer, metabolic alterations such as increased liver enzymes and increased cholesterol, immune dysfunction such as reduced vaccination …

Biodegradable Pcl–Plga Electrospun Nanofibers For Localized Cancer Therapy, Rahul Tiwari, Pranav, Joel Delossantos, Eswara N.H.K. Ghali, Luis Chavez, Vishal Sharad Chaudhari, Songyang Han, Subhash Chauhan, Murali Yallapu

School of Medicine Publications

Localized chemotherapy offers a promising strategy to improve therapeutic efficacy while minimizing the systemic toxicity of conventional cancer treatment, particularly following tumor resection. Electrospun nanofibers are well suited for this purpose due to their high porosity, extracellular matrix-mimicking architecture, and capacity for localized drug release. In this study, electrospun nanofibers based on PCL and PLGA were developed for localized cancer therapy. Three distinct nanofibrous architectures were fabricated: PCL nanofibers, PCL−PLGA blended nanofibers, and PCL−PLGA multilayered (tetra-layered) nanofibers, and their encapsulation efficiency was determined by high-performance liquid chromatography (HPLC). Scanning electron microscopy confirmed uniform, bead-free nanofibrous morphologies, while Fourier transform infrared …

Assessment Of The Bioremediation Potentials Of Biosurfactant-Producing Bacterial Strains Recovered From Spent Engine Oil-Contaminated Environments In Southwest Nigeria, Nafisa Mohammed Babayola, Nasiru Bright Lecky, Chinweizu Obioma Onumaegbu, Olufunmiso Olusola Olajuyigbe, Martins Ajibade Adefisoye

Journal of Environmental Science and Sustainable Development

Environmental pollution from hydrocarbons and their derivatives is predominantly of anthropogenic origin, occurring mainly during mining, transportation, and storage. This often in an annual release of substantial amounts of pollutants into the environment. The effective restoration of petroleum-contaminated environments requires a series of interventions to remediate soil to its natural state. This study aimed to isolate and characterize biosurfactant-producing bacterial strains with potential bioremediation capabilities to assess the potential application for remediating soils polluted with spent engine oil in the Remo district, Ogun State. Bacterial isolates were recovered from soil samples collected from spent engine oil contaminated sites, using standard …

Toxoplasmosis-Associated Immune Reconstitution Inflammatory Syndrome In A Patient With Newly Diagnosed Hiv/Aids, Shivam Singh, Divya Samat Md, Viraj Shah, Kelly Brenan-Rothschild, Anthony Donato

Advances in Clinical Medical Research and Healthcare Delivery

Background: Cerebral toxoplasmosis is a common cause of central nervous system (CNS) lesions in advanced HIV, and initiation of antiretroviral therapy (ART) can precipitate immune reconstitution inflammatory syndrome (IRIS). Toxoplasma-related IRIS is rare but poses significant diagnostic and therapeutic challenges. Case Presentation: We report a 40-year-old male with advanced HIV (CD4 <35 cells/mm3, viral load 540,000 copies/mL) who initially presented with seizures and multiple ring-enhancing supratentorial lesions. Serology and cerebrospinal fluid (CSF) polymerase chain reaction (PCR) confirmedToxoplasma gondii, and he was treated with high-dose sulfamethoxazole-trimethoprim, dexamethasone, and ART. A lymph node biopsy revealed granulomatous inflammation with intracellularHistoplasmaspecies. One month later, following brief interruption of anti-toxoplasma therapy, he developed recurrent seizures and radiographic progression despite ART adherence. Repeat evaluation excluded other infections or malignancy. Brain biopsy confirmedT. gondii, and IRIS was diagnosed. The patient improved with re-initiation of high-dose anti-toxoplasma therapy, corticosteroids, and seizure prophylaxis. Discussion: This case illustrates paradoxical toxoplasmosis-associated IRIS in the context of advanced HIV and concurrent opportunistic infection. Early recognition, exclusion of alternative diagnoses, and continuation of ART with targeted antimicrobial therapy are essential. Conclusion: Clinicians should maintain a high index of suspicion for IRIS in HIV patients with CNS …

Vitamin D Deficiency And Risk Of Cognitive Decline And Dementia: Implications And Prevention Strategies, Auda Fares

Advances in Clinical Medical Research and Healthcare Delivery

Emerging evidence suggests a link between vitamin D deficiency and an increased risk of cognitive impairment and dementia, including Alzheimer's disease (AD). This paper reviews the epidemiological evidence, explores potential mechanisms underlying this association, and discusses implications for prevention strategies. Current supplementation strategies may not be fully effective due to individual variability. Personalized interventions based on genetic factors and routine vitamin D status testing in older adults are proposed as future directions for optimizing the impact of vitamin D supplementation in dementia prevention.

Gci-312 — Adaptive Agricultural Microclimate Conditioning System For Arid Environments, Michael Victor Caldwell Mr.

Defensive Publications Series

GCI‑312 is an open‑source, prototype‑ready adaptive agricultural microclimate conditioning system integrating electrostatic‑assisted droplet deposition, vortex atomization, pulsed evaporative cooling, environmental telemetry, and root‑zone thermal stabilization to experimentally reduce convective moisture loss and crop heat stress in arid environments. This disclosure provides full build and test specifications so a reader can assemble a 10×10 ft test cell and begin staged experiments immediately. The project targets substantial irrigation demand reductions under arid heat‑stress conditions (experimental targets: 20–30% irrigation reduction; exploratory upper target if all subsystems validate: up to 30–50% reduction) and documents clear hypotheses, test metrics, kill criteria, pivot paths, energy accounting, …

Municipal Wet-Food Recovery & Supplemental Fertilizer Pellet System, Michael Victor Caldwell Mr.

Defensive Publications Series

This disclosure describes a simplified municipal waste-recovery system designed to:

• recover expired canned foods and wet household food waste,

• recycle steel and aluminum food containers,

• reduce landfill methane generation,

• reduce municipal landfill burden,

• and produce supplemental fertilizer pellets intended for blending with conventional agricultural fertilizers.

Unlike conventional composting systems requiring extensive sorting, this architecture intentionally focuses ONLY on:

• wet food waste,

• spoiled food,

• and canned food products.

The system uses:

• sealed household collection bins,

• dedicated sanitary pickup trucks,

• low-shear food recovery processing,

• metal separation,

• thermal sanitization,

• dewatering,

• and conventional pelletization equipment.

Survival And Factors Associated With Mortality Among Patients With Oral Cancer At A Tertiary Hospital In Northeastern Thailand: A Retrospective Cohort Study, Somkiattiyos Woradet, Bhunyabhadh Chaimay, Nuntiput Putthanachote

Journal of Health Research

Background: Oral cancer is a major cause of premature mortality in Thailand. This study examines survival and prognostic factors in a northeastern tertiary-care setting.

Methods: A hospital-based retrospective cohort study was conducted using the Cancer Registry and medical records in a tertiary care hospital in Northeastern, Thailand. Patients diagnosed with oral cancer between January 2005 and December 2015 and followed until death or February 2020. Overall survival was estimated using the Kaplan–Meier method. Cox proportional hazards models were used to assess factors associated with mortality

Results: The median survival time was 18.67 months (95% confidence interval [CI]: 15.70–22.83). It revealed …

Pertanggungjawaban Indonesia Terhadap Pencemaran Kabut Asap Di Kawasan Asean (Pendekatan Economic Analysis Of Law), Deni Bram

Jurnal Hukum & Pembangunan

Abstract

Perempuan Dan Hak Asasi Manusia Dalam Perspektif Hukum Islam, Uswatun Hasanah

Jurnal Hukum & Pembangunan

Abstract

The Necessity Of Capacity Building For Indonesia's Effective Utilization Of Wto Dispute Settlement Mechanism: Implementation Of Gait Article Xx For Trade And Environment Issues, Windu Kisworo

Jurnal Hukum & Pembangunan

Abstract

Big Game License Fees—Seeking Price Optimization Equity, Chip E. Miller, Brian Vander Naald

Atlantic Marketing Association Proceedings

No abstract provided.

A Shift In The Respiratory Syncytial Virus Seasonal Pattern: A Single–Center Retrospective Study In Anhui, China (2023–2025), Yan Lu, Jie Zhang, Keran Zhu, Li Wang, Shenggang Ding, Liping Yuan

Journal of Pediatric Infectious Diseases

Objective: Before the coronavirus disease 2019 pandemic, respiratory syncytial virus (RSV)-related hospitalizations followed a predictable seasonal pattern in Anhui, China, typically beginning in November and lasting until March of the following year. However, city-specific data for Anhui were limited. This study investigated the epidemiological patterns and risk factors associated with severe RSV-associated lower respiratory tract infection (LRTI) among hospitalized children in our centre. Methods: We reviewed the records of children aged ≤14 years who were hospitalized with RSV lower respiratory tract infection between June 2023 and May 2025. RSV infection was confirmed using reverse transcription-polymerase chain reaction testing. Data on …

A Clinical Risk Stratification Approach For Sensorineural Hearing Loss In Pediatric Bacterial Meningitis: A Retrospective Cohort Study From Vietnam, Nguyen D. Pham, Toan M. Duong

Journal of Pediatric Infectious Diseases

Objective: To address the long-term burden of sensorineural hearing loss (SNHL) following pediatric bacterial meningitis and the need for early identification of at-risk children, particularly in resource-limited settings where universal post-meningitis screening is impractical. This study aimed to develop a clinically accessible risk stratification approach, using routinely available variables, to support triage and prioritization of audiological follow-up. Methods: A retrospective cohort study was conducted at Children’s Hospital 1, Ho Chi Minh City, Vietnam. Children aged 1 month to 15 years, who were hospitalized with bacterial meningitis and underwent audiological assessment after recovery, were included. Hearing outcomes were evaluated by auditory …