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Nitric Oxide Releases Cl− From Acidic Organelles In Retinal Amacrine Cells, Vijai Krishnan, Evanna Gleason Jun 2015

Nitric Oxide Releases Cl− From Acidic Organelles In Retinal Amacrine Cells, Vijai Krishnan, Evanna Gleason

Faculty Publications

© 2015 Krishnan and Gleason Determining the factors regulating cytosolic Cl− in neurons is fundamental to our understanding of the function of GABA- and glycinergic synapses. This is because the Cl− distribution across the postsynaptic plasma membrane determines the sign and strength of postsynaptic voltage responses. We have previously demonstrated that nitric oxide (NO) releases Cl− into the cytosol from an internal compartment in both retinal amacrine cells and hippocampal neurons. Furthermore, we have shown that the increase in cytosolic Cl− is dependent upon a decrease in cytosolic pH. Here, our goals were to confirm the compartmental nature of the …

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Incorporation Of Iodine Into Apatite Structure: A Crystal Chemistry Approach Using Artificial Neural Network, Jianwei Wang Jun 2015

Incorporation Of Iodine Into Apatite Structure: A Crystal Chemistry Approach Using Artificial Neural Network, Jianwei Wang

Faculty Publications

© 2015 Wang. Materials with apatite crystal structure have a great potential for incorporating the long-lived radioactive iodine isotope (129 I) in the form of iodide (I−) from nuclear waste streams. Because of its durability and potentially high iodine content, the apatite waste form can reduce iodine release rate and minimize the waste volume. Crystal structure and composition of apatite (A5 (XO4)3 Z) was investigated for iodide incorporation into the channel of the structure using Artificial Neural Network. A total of 86 experimentally determined apatite crystal structures of different compositions were compiled from literature, and 44 of them were used …

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Directional Sound Sensitivity In Utricular Afferents In The Toadfish Opsanus Tau, Karen P. Maruska, Allen F. Mensinger Jun 2015

Directional Sound Sensitivity In Utricular Afferents In The Toadfish Opsanus Tau, Karen P. Maruska, Allen F. Mensinger

Faculty Publications

© 2015 Published by The Company of Biologists Ltd. The inner ear of fishes contains three paired otolithic end organs, the saccule, lagena and utricle, which function as biological accelerometers. The saccule is the largest otolith in most fishes and much of our current understanding on auditory function in this diverse group of vertebrates is derived from anatomical and neurophysiological studies on this end organ. In contrast, less is known about how the utricle contributes to auditory functions. In this study, chronically implanted electrodes were used, along with neural telemetry or tethers to record primary afferent responses from the utricular …

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Ucp1 Is An Essential Mediator Of The Effects Of Methionine Restriction On Energy Balance But Not Insulin Sensitivity, Desiree Wanders, David H. Burk, Cory C. Cortez, Nancy T. Van, Kirsten P. Stone, Mollye Baker, Tamra Mendoza, Randall L. Mynatt, Thomas W. Gettys Jun 2015

Ucp1 Is An Essential Mediator Of The Effects Of Methionine Restriction On Energy Balance But Not Insulin Sensitivity, Desiree Wanders, David H. Burk, Cory C. Cortez, Nancy T. Van, Kirsten P. Stone, Mollye Baker, Tamra Mendoza, Randall L. Mynatt, Thomas W. Gettys

Faculty Publications

© FASEB. Dietary methionine restriction (MR) by 80%increases energy expenditure (EE), reduces adiposity, and improves insulin sensitivity. We propose that the MRinduced increase in EE limits fat deposition by increasing sympathetic nervous system-dependent remodeling of white adipose tissue and increasing uncoupling protein 1 (UCP1) expression in both white and brown adipose tissue. In independent assessments of the role of UCP1 as a mediator of MR's effects on EE and insulin sensitivity, EE did not differ between wild-type (WT) and Ucp1-/- mice on the control diet, butMR increased EE by 31%and reduced adiposity by 25% in WT mice. In contrast, …

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Accelerating The Pace Of Protein Functional Annotation With Intel Xeon Phi Coprocessors, Wei P. Feinstein, Juana Moreno, Mark Jarrell, Michal Brylinski Jun 2015

Accelerating The Pace Of Protein Functional Annotation With Intel Xeon Phi Coprocessors, Wei P. Feinstein, Juana Moreno, Mark Jarrell, Michal Brylinski

Faculty Publications

© 2002-2011 IEEE. Intel Xeon Phi is a new addition to the family of powerful parallel accelerators. The range of its potential applications in computationally driven research is broad; however, at present, the repository of scientific codes is still relatively limited. In this study, we describe the development and benchmarking of a parallel version of {\mmb e}FindSite, a structural bioinformatics algorithm for the prediction of ligand-binding sites in proteins. Implemented for the Intel Xeon Phi platform, the parallelization of the structure alignment portion of {\mmb e}FindSite using pragma-based OpenMP brings about the desired performance improvements, which scale well with the …

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Resistance To Aspergillus Flavus In Maize And Peanut: Molecular Biology, Breeding, Environmental Stress, And Future Perspectives, Jake C. Fountain, Pawan Khera, Liming Yang, Spurthi N. Nayak, Brian T. Scully, Robert D. Lee, Zhi Yuan Chen, Robert C. Kemerait, Rajeev K. Varshney, Baozhu Guo Jun 2015

Resistance To Aspergillus Flavus In Maize And Peanut: Molecular Biology, Breeding, Environmental Stress, And Future Perspectives, Jake C. Fountain, Pawan Khera, Liming Yang, Spurthi N. Nayak, Brian T. Scully, Robert D. Lee, Zhi Yuan Chen, Robert C. Kemerait, Rajeev K. Varshney, Baozhu Guo

Faculty Publications

The colonization of maize (Zea mays L.) and peanut (Arachis hypogaea L.) by the fungal pathogen Aspergillus flavus results in the contamination of kernels with carcinogenic mycotoxins known as aflatoxins leading to economic losses and potential health threats to humans. The regulation of aflatoxin biosynthesis in various Aspergillus spp. has been extensively studied, and has been shown to be related to oxidative stress responses. Given that environmental stresses such as drought and heat stress result in the accumulation of reactive oxygen species (ROS) within host plant tissues, host-derived ROS may play an important role in cross-kingdom communication between host plants …

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Ccl20 Is Elevated During Obesity And Differentially Regulated By Nf-Κb Subunits In Pancreatic Β-Cells, Susan J. Burke, Michael D. Karlstad, Kellie M. Regal, Tim E. Sparer, Danhong Lu, Carrie M. Elks, Ryan W. Grant, Jacqueline M. Stephens, David H. Burk, J. Jason Collier Jun 2015

Ccl20 Is Elevated During Obesity And Differentially Regulated By Nf-Κb Subunits In Pancreatic Β-Cells, Susan J. Burke, Michael D. Karlstad, Kellie M. Regal, Tim E. Sparer, Danhong Lu, Carrie M. Elks, Ryan W. Grant, Jacqueline M. Stephens, David H. Burk, J. Jason Collier

Faculty Publications

© 2015 Elsevier B.V. Enhanced leukocytic infiltration into pancreatic islets contributes to inflammation-based diminutions in functional β-cell mass. Insulitis (aka islet inflammation), which can be present in both T1DM and T2DM, is one factor influencing pancreatic β-cell death and dysfunction. IL-1β, an inflammatory mediator in both T1DM and T2DM, acutely (within 1. h) induced expression of the CCL20 gene in rat and human islets and clonal β-cell lines. Transcriptional induction of CCL20 required the p65 subunit of NF-κB to replace the p50 subunit at two functional κB sites within the CCL20 proximal gene promoter. The NF-κB p50 subunit prevents CCL20 …

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Deletion Of The Proposed Iron Chaperones Isca/Sufa Results In Accumulation Of A Red Intermediate Cysteine Desulfurase Iscs In Escherichia Coli, Jing Yang, Guoqiang Tan, Ting Zhang, Robert H. White, Jianxin Lu, Huangen Ding May 2015

Deletion Of The Proposed Iron Chaperones Isca/Sufa Results In Accumulation Of A Red Intermediate Cysteine Desulfurase Iscs In Escherichia Coli, Jing Yang, Guoqiang Tan, Ting Zhang, Robert H. White, Jianxin Lu, Huangen Ding

Faculty Publications

© 2015 by The American Society for Biochemistry and Molecular Biology, Inc. In Escherichia coli, sulfur in iron-sulfur clusters is primarily derived from L-cysteine via the cysteine desulfurase IscS. However, the iron donor for iron-sulfur cluster assembly remains elusive. Previous studies have shown that, among the iron-sulfur cluster assembly proteins in E. coli, IscA has a unique and strong iron-binding activity and that the iron-bound IscA can efficiently provide iron for iron-sulfur cluster assembly in proteins in vitro, indicating that IscA may act as an iron chaperone for iron-sulfur cluster biogenesis. Here we report that deletion of IscA and its …

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An Extract Of Artemisia Dracunculus L. Stimulates Insulin Secretion From Β Cells, Activates Ampk And Suppresses Inflammation, Sita Aggarwal, Giri Shailendra, David M. Ribnicky, David Burk, Namrata Karki, M. S. Qingxia Wang May 2015

An Extract Of Artemisia Dracunculus L. Stimulates Insulin Secretion From Β Cells, Activates Ampk And Suppresses Inflammation, Sita Aggarwal, Giri Shailendra, David M. Ribnicky, David Burk, Namrata Karki, M. S. Qingxia Wang

Faculty Publications

© 2015 Elsevier Ireland Ltd. All rights reserved. Ethnopharmacological relevance Artemisia dracunculus L. (Russian tarragon) is a perennial herb belonging to the family Compositae and has a history of medicinal use in humans, particularly for treatment of diabetes. Aim of the study: In this study a defined plant extract from A. dracunculus L. (termed PMI-5011) is used to improve beta(β) cells function and maintain β cell number in pancreatic islets as an alternative drug approach for successful treatment of diabetes. Materials and methods Mouse and human pancreatic beta cells were treated with defined plant extract of A. dracunculus L. (PMI-5011) …

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Thiobenzothiazole-Modified Hydrocortisones Display Anti-Inflammatory Activity With Reduced Impact On Islet Β-Cell Function, Susan J. Burke, Amanda L. May, Robert C. Noland, Danhong Lu, Marcela Brissova, Alvin C. Powers, Elizabeth M. Sherrill, Michael D. Karlstad, Shawn R. Campagna, Jacqueline M. Stephens, J. Jason Collier May 2015

Thiobenzothiazole-Modified Hydrocortisones Display Anti-Inflammatory Activity With Reduced Impact On Islet Β-Cell Function, Susan J. Burke, Amanda L. May, Robert C. Noland, Danhong Lu, Marcela Brissova, Alvin C. Powers, Elizabeth M. Sherrill, Michael D. Karlstad, Shawn R. Campagna, Jacqueline M. Stephens, J. Jason Collier

Faculty Publications

© 2015, American Society for Biochemistry and Molecular Biology Inc. All rights reserved. Glucocorticoids signal through the glucocorticoid receptor (GR) and are administered clinically for a variety of situations, including inflammatory disorders, specific cancers, rheumatoid arthritis, and organ/tissue transplantation. However, glucocorticoid therapy is also associated with additional complications, including steroid-induced diabetes. We hypothesized that modification of the steroid backbone is one strategy to enhance the therapeutic potential of GR activation. Toward this goal, two commercially unavailable, thiobenzothiazole-containing derivatives of hydrocortisone (termed MS4 and MS6) were examined using 832/13 rat insulinoma cells as well as rodent and human islets. We found …

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Risk-Optimized Proton Therapy To Minimize Radiogenic Second Cancers, Laura A. Rechner, John G. Eley, Rebecca M. Howell, Rui Zhang, Dragan Mirkovic, Wayne D. Newhauser May 2015

Risk-Optimized Proton Therapy To Minimize Radiogenic Second Cancers, Laura A. Rechner, John G. Eley, Rebecca M. Howell, Rui Zhang, Dragan Mirkovic, Wayne D. Newhauser

Faculty Publications

Proton therapy confers substantially lower predicted risk of second cancer compared with photon therapy. However, no previous studies have used an algorithmic approach to optimize beam angle or fluence-modulation for proton therapy to minimize those risks. The objectives of this study were to demonstrate the feasibility of risk-optimized proton therapy and to determine the combination of beam angles and fluence weights that minimizes the risk of second cancer in the bladder and rectum for a prostate cancer patient. We used 6 risk models to predict excess relative risk of second cancer. Treatment planning utilized a combination of a commercial treatment …

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An Analytical Model Of Leakage Neutron Equivalent Dose For Passively-Scattered Proton Radiotherapy And Validation With Measurements, Christopher Schneider, Wayne Newhauser, Jad Farah May 2015

An Analytical Model Of Leakage Neutron Equivalent Dose For Passively-Scattered Proton Radiotherapy And Validation With Measurements, Christopher Schneider, Wayne Newhauser, Jad Farah

Faculty Publications

Exposure to stray neutrons increases the risk of second cancer development after proton therapy. Previously reported analytical models of this exposure were difficult to configure and had not been investigated below 100 MeV proton energy. The purposes of this study were to test an analytical model of neutron equivalent dose per therapeutic absorbed dose at 75 MeV and to improve the model by reducing the number of configuration parameters and making it continuous in proton energy from 100 to 250 MeV. To develop the analytical model, we used previously published H/D values in water from Monte Carlo simulations of a …

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A Kazal-Type Serine Protease Inhibitor From The Defense Gland Secretion Of The Subterranean Termite Coptotermes Formosanus Shiraki, Horia Negulescu, Youzhong Guo, Thomas P. Garner, Octavia Y. Goodwin, Gregg Henderson, Roger A. Laine, Megan A. Macnaughtan May 2015

A Kazal-Type Serine Protease Inhibitor From The Defense Gland Secretion Of The Subterranean Termite Coptotermes Formosanus Shiraki, Horia Negulescu, Youzhong Guo, Thomas P. Garner, Octavia Y. Goodwin, Gregg Henderson, Roger A. Laine, Megan A. Macnaughtan

Faculty Publications

© 2015 Negulescu et al. Coptotermes formosanus is an imported, subterranean termite species with the largest economic impact in the United States. The frontal glands of the soldier caste termites comprising one third of the body mass, contain a secretion expelled through a foramen in defense. The small molecule composition of the frontal gland secretion is well-characterized, but the proteins remain to be identified. Herein is reported the structure and function of one of several proteins found in the termite defense gland secretion. TFP4 is a 6.9 kDa, non-classical group 1 Kazal-type serine protease inhibitor with activity towards chymotrypsin and …

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A Kazal-Type Serine Protease Inhibitor From The Defense Gland Secretion Of The Subterranean Termite Coptotermes Formosanus Shiraki, Horia Negulescu, Youzhong Guo, Thomas P. Garner, Octavia Y. Goodwin, Gregg Henderson, Roger A. Laine, Megan A. Macnaughtan May 2015

A Kazal-Type Serine Protease Inhibitor From The Defense Gland Secretion Of The Subterranean Termite Coptotermes Formosanus Shiraki, Horia Negulescu, Youzhong Guo, Thomas P. Garner, Octavia Y. Goodwin, Gregg Henderson, Roger A. Laine, Megan A. Macnaughtan

Faculty Publications

© 2015 Negulescu et al. Coptotermes formosanus is an imported, subterranean termite species with the largest economic impact in the United States. The frontal glands of the soldier caste termites comprising one third of the body mass, contain a secretion expelled through a foramen in defense. The small molecule composition of the frontal gland secretion is well-characterized, but the proteins remain to be identified. Herein is reported the structure and function of one of several proteins found in the termite defense gland secretion. TFP4 is a 6.9 kDa, non-classical group 1 Kazal-type serine protease inhibitor with activity towards chymotrypsin and …

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Biological Evidence Supports An Early And Complex Emergence Of The Isthmus Of Panama, Christine D. Bacona, Daniele Silvestro, Carlos Jaramillo, Brian Tilston Smith, Prosanta Chakrabarty, Alexandre Antonelli May 2015

Biological Evidence Supports An Early And Complex Emergence Of The Isthmus Of Panama, Christine D. Bacona, Daniele Silvestro, Carlos Jaramillo, Brian Tilston Smith, Prosanta Chakrabarty, Alexandre Antonelli

Faculty Publications

The linking of North and South America by the Isthmus of Panama had major impacts on global climate, oceanic and atmospheric currents, and biodiversity, yet the timing of this critical event remains contentious. The Isthmus is traditionally understood to have fully closed by ca. 3.5 million years ago (Ma), and this date has been used as a benchmark for oceanographic, climatic, and evolutionary research, but recent evidence suggests a more complex geological formation. Here, we analyze both molecular and fossil data to evaluate the tempo of biotic exchange across the Americas in light of geological evidence. We demonstrate significant waves …

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A Bayesian Dose-Finding Design For Phase I/Ii Clinical Trials With Nonignorable Dropouts, Beibei Guo, Ying Yuan May 2015

A Bayesian Dose-Finding Design For Phase I/Ii Clinical Trials With Nonignorable Dropouts, Beibei Guo, Ying Yuan

Faculty Publications

Phase I/II trials utilize both toxicity and efficacy data to achieve efficient dose finding. However, due to the requirement of assessing efficacy outcome, which often takes a long period of time to be evaluated, the duration of phase I/II trials is often longer than that of the conventional dose-finding trials. As a result, phase I/II trials are susceptible to the missing data problem caused by patient dropout, and the missing efficacy outcomes are often nonignorable in the sense that patients who do not experience treatment efficacy are more likely to drop out of the trial. We propose a Bayesian phase …

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Induction Of Energy Expenditure By Sitagliptin Is Dependent On Glp-1 Receptor, Felicia Goldsmith, Michael J. Keenan, Anne M. Raggio, Xin Ye, Zheng Hao, Holiday Durham, James Geaghan, Weiping Jia, Roy J. Martin, Jianping Ye May 2015

Induction Of Energy Expenditure By Sitagliptin Is Dependent On Glp-1 Receptor, Felicia Goldsmith, Michael J. Keenan, Anne M. Raggio, Xin Ye, Zheng Hao, Holiday Durham, James Geaghan, Weiping Jia, Roy J. Martin, Jianping Ye

Faculty Publications

Sitagliptin (SG) increases serum GLP-1 (Glucagon-like peptide-1) through inhibition of the hormone degradation. Resistant starch (RS) induces GLP-1 expression by stimulating L-cells in the intestine. Sitagliptin and resistant starch may have a synergistic interaction in the induction of GLP-1. This possibility was tested in current study in a mouse model of type 2 diabetes. Hyperglycemia was induced in the diet-induced obese mice by a signal injection of streptozotocin (STZ). Sitagliptin (0.4g/100g diet) was tested in the mice (n = 55) with dietary RS (HAM-RS2) at three dosages (0, 15, or 28g/100g diet). Energy and glucose metabolism were monitored in the …

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Expansion Of Brucellosis Detection In The Country Of Georgia By Screening Household Members Of Cases And Neighboring Community Members, Lia Sanodze, Christian T. Bautista, Natalia Garuchava, Svetlana Chubinidze, Ekaterine Tsertsvadze, Mariam Broladze, Nazibrola Chitadze, Ketevan Sidamonidze, Shota Tsanava, Tamar Akhvlediani, Robert G. Rivard, Rupal Mody, Matthew J. Hepburn, Philip H. Elzer, Mikeljon P. Nikolich, Nino Trapaidze May 2015

Expansion Of Brucellosis Detection In The Country Of Georgia By Screening Household Members Of Cases And Neighboring Community Members, Lia Sanodze, Christian T. Bautista, Natalia Garuchava, Svetlana Chubinidze, Ekaterine Tsertsvadze, Mariam Broladze, Nazibrola Chitadze, Ketevan Sidamonidze, Shota Tsanava, Tamar Akhvlediani, Robert G. Rivard, Rupal Mody, Matthew J. Hepburn, Philip H. Elzer, Mikeljon P. Nikolich, Nino Trapaidze

Faculty Publications

© 2015 Sanodze et al.; licensee BioMed Central. Background: Brucellosis is considered as endemic zoonotic disease in the country of Georgia. However, the burden of the disease on a household level is not known. Therefore, this study sought to determine the benefits of active surveillance coupled to serological screening for the early detection of brucellosis among close contacts of brucellosis cases. Methods: We used an active surveillance approach to estimate the rate of seropositivity among household family members and neighboring community members of brucellosis index cases. All participants were screened using the serum tube agglutination test (SAT). Blood cultures were …

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Plant Neighborhood Effects On Herbivory: Damage Is Both Density And Frequency Dependent, Tania N. Kim, Nora Underwood, J. T. Cronin May 2015

Plant Neighborhood Effects On Herbivory: Damage Is Both Density And Frequency Dependent, Tania N. Kim, Nora Underwood, J. T. Cronin

Faculty Publications

© 2015 by the Ecological Society of America. Neighboring plants can affect the likelihood that a focal plant is attacked by herbivores. Both the density of conspecific neighbors (resource concentration or dilution effects) and the relative density of heterospecific neighbors (associational effects or effects of neighbor frequency) within the local neighborhood can affect herbivore load and plant damage. Understanding how these neighborhood effects influence processes such as plant competition or natural selection on plant resistance traits will require knowing how both plant density and frequency affect damage, but previous studies have generally confounded density and frequency effects. In this study, …

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Deflating Trees: Improving Bayesian Branch-Length Estimates Using Informed Priors, Bradley J. Nelson, John J. Andersen, Jeremy M. Brown May 2015

Deflating Trees: Improving Bayesian Branch-Length Estimates Using Informed Priors, Bradley J. Nelson, John J. Andersen, Jeremy M. Brown

Faculty Publications

© 2015 © The Author(s) 2015. Published by Oxford University Press, on behalf of the Society of Systematic Biologists. All rights reserved. For Permissions, please email: [email protected]. Prior distributions can have a strong effect on the results of Bayesian analyses. However, no general consensus exists for how priors should be set in all circumstances. Branch-length priors are of particular interest for phylogenetics, because they affect many parameters and biologically relevant inferences have been shown to be sensitive to the chosen prior distribution. Here, we explore the use of outside information to set informed branch-length priors and compare inferences from these …

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A Second Corticotropin-Releasing Hormone Gene (Crh2) Is Conserved Across Vertebrate Classes And Expressed In The Hindbrain Of A Basal Neopterygian Fish, The Spotted Gar (Lepisosteus Oculatus), Brian P. Grone, Karen P. Maruska May 2015

A Second Corticotropin-Releasing Hormone Gene (Crh2) Is Conserved Across Vertebrate Classes And Expressed In The Hindbrain Of A Basal Neopterygian Fish, The Spotted Gar (Lepisosteus Oculatus), Brian P. Grone, Karen P. Maruska

Faculty Publications

© 2015 Wiley Periodicals, Inc. To investigate the origins of the vertebrate stress-response system, we searched sequenced vertebrate genomes for genes resembling corticotropin-releasing hormone (CRH). We found that vertebrate genomes possess, in addition to CRH, another gene that resembles CRH in sequence and syntenic environment. This paralogous gene was previously identified only in the elephant shark (a holocephalan), but we find it also in marsupials, monotremes, lizards, turtles, birds, and fishes. We examined the relationship of this second vertebrate CRH gene, which we name CRH2, to CRH1 (previously known as CRH) and urocortin1/urotensin1 (UCN1/UTS1) in primitive fishes, teleosts, and tetrapods. …

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The Influence Of Polyamines On The Hypotonic Shock Response In The Euryhaline Teleost, Fundulus Grandis, Keith Lasko May 2015

The Influence Of Polyamines On The Hypotonic Shock Response In The Euryhaline Teleost, Fundulus Grandis, Keith Lasko

Honors Capstones

No abstract provided.

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Synthesis, Functionalization, And Characterization Of Metallic And Organic Nanoparticles For Biomedical Applications, Christopher Brian Sylvester May 2015

Synthesis, Functionalization, And Characterization Of Metallic And Organic Nanoparticles For Biomedical Applications, Christopher Brian Sylvester

Honors Capstones

No abstract provided.

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Encoding Knots, Rachael Keller May 2015

Encoding Knots, Rachael Keller

Honors Capstones

No abstract provided.

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Patterns Of Survival And Roost Switching In An African Insectivorous Bat, A. Monadjem, R. A. Mccleery, B. Collier May 2015

Patterns Of Survival And Roost Switching In An African Insectivorous Bat, A. Monadjem, R. A. Mccleery, B. Collier

Faculty Publications

Variation in survival over time and among age and sex classes drives population dynamics for a large majority of long-lived species and is critical to understanding species demography. For highly mobile species that actively move among potential breeding locations, coupling survival information with estimates of locational fidelity provides the basis for our understanding of species population dynamics. We studied the effect of time, age and sex class and climatic variables on survival and roost transition probabilities on a population of Egyptian slit-faced bats in Swaziland from 1450 marked individuals from 16 roosts over a 10-year period. We then used variance …

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The Economic Impacts And Changes In Environmental Regulation In Louisiana As A Result Of Hurricane Katrina And The Deepwater Horizon Oil Spill, Carley Tatman May 2015

The Economic Impacts And Changes In Environmental Regulation In Louisiana As A Result Of Hurricane Katrina And The Deepwater Horizon Oil Spill, Carley Tatman

Honors Capstones

No abstract provided.

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Isolation And Characterization Of A Novel Extremely Halophilic Euryarchaeota From Hypersaline Cinders And Sediment, Shannon Mcduff May 2015

Isolation And Characterization Of A Novel Extremely Halophilic Euryarchaeota From Hypersaline Cinders And Sediment, Shannon Mcduff

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No abstract provided.

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The Successional Grid, Erin Percevault May 2015

The Successional Grid, Erin Percevault

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No abstract provided.

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Studies To Elucidate The Location And Function Of Stat5a/Pyruvate Dehydrogenase Complex In Adipocytes, Hardy Hang May 2015

Studies To Elucidate The Location And Function Of Stat5a/Pyruvate Dehydrogenase Complex In Adipocytes, Hardy Hang

Honors Capstones

No abstract provided.

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Employing Extracellular Vesicles To Overcome Immunological Barriers To Aav- Mediated Gene Transfer & Ethical And Policy Implications Of Orphan Drug Development And Accessibility, Zachary Fitzpatrick May 2015

Employing Extracellular Vesicles To Overcome Immunological Barriers To Aav- Mediated Gene Transfer & Ethical And Policy Implications Of Orphan Drug Development And Accessibility, Zachary Fitzpatrick

Honors Capstones

No abstract provided.

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