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Efficacy Of Entomopathogenic Nematodes And Sprayable Polymer Gel Against Crucifer Flea Beetle (Coleoptera: Chrysomelidae) On Canola, Frank B. Antwi, Gadi V.P. Reddy Aug 2016

Efficacy Of Entomopathogenic Nematodes And Sprayable Polymer Gel Against Crucifer Flea Beetle (Coleoptera: Chrysomelidae) On Canola, Frank B. Antwi, Gadi V.P. Reddy

Faculty Publications

The crucifer flea beetle, Phyllotreta cruciferae (Goeze), is a key pest of canola (Brassica napus L.) in the northern Great Plains of North America. The efficacies of entomopathogenic nematodes (Steinernema spp. and Heterorhabditis spp.), a sprayable polymer gel, and a combination of both were assessed on canola for flea beetle management. Plots were treated soon after colonization by adult flea beetles, when canola was in the cotyledon to one-leaf stage. Ten plants along a 3.6-m section of row were selected and rated at pre-treatment and 7 and 14 d post treatment using the damage-rating scheme advanced by the European Plant …

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Association Between 25-Hydroxyvitamin D And Intact Parathyroid Hormone Levels Across Latitude Among Adults With African Ancestry, Holly Kramer, Pauline Camacho, John Aloia, Amy Luke, Pascal Bovet, Jacob Plange Rhule, Terrence Forrester, Vickie Lambert, Regina Harders, Lara Dugas, Richard Cooper, Ramon Durazo-Arvizu Aug 2016

Association Between 25-Hydroxyvitamin D And Intact Parathyroid Hormone Levels Across Latitude Among Adults With African Ancestry, Holly Kramer, Pauline Camacho, John Aloia, Amy Luke, Pascal Bovet, Jacob Plange Rhule, Terrence Forrester, Vickie Lambert, Regina Harders, Lara Dugas, Richard Cooper, Ramon Durazo-Arvizu

Faculty Publications

Objective: To compare levels of 25-hydroxyvitamin D (25OHD) associated with a plateauing of intact parathyroid (iPTH) across latitudes among adults with African ancestry. Methods: This study included approximately 500 adults of African ancestry ages 25 to 45 years living in 4 sites: Chicago, Illinois (41°N), Jamaica (17°N), Ghana (6°N), and South Africa (34°S). Multivariate linear regression models, a nonlinear logistic growth curve model, and piecewise linear models with a single knot were fitted to estimate the 25OHD level associated with a plateauing of iPTH with adjustment for covariates. Goodness of fit was compared using computer intensive permutation tests. Results: Mean …

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Spatiotemporal Distributions Of Sr And Ba Along An Estuarine River With A Large Salinity Gradient To The Gulf Of Mexico, Songjie He, Y. Jun Xu Aug 2016

Spatiotemporal Distributions Of Sr And Ba Along An Estuarine River With A Large Salinity Gradient To The Gulf Of Mexico, Songjie He, Y. Jun Xu

Faculty Publications

Strontium and barium to calcium ratios are often used as proxies for tracking animal movement across salinity gradients. Many estuarine rivers face saltwater intrusion due to sea level rise, potentially causing changes in mobility and distribution of these metals upstream. From May 2013 to August 2015, monthly water samples were collected and in-situ measurements were performed at six sites along an estuary strongly affected by saltwater intrusion, the Calcasieu River, with salinity ranging from 0.02 to 29.50 Parts Per Thousand (ppt). Results showed that the total Sr concentration and the Sr/Ca ratio both increased significantly with increasing salinity. The average …

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Progress And Prospects Of Reactive Oxygen Species In Metal Carcinogenesis, Lei Wang, James T.F. Wise, Zhuo Zhang, Xianglin Shi Aug 2016

Progress And Prospects Of Reactive Oxygen Species In Metal Carcinogenesis, Lei Wang, James T.F. Wise, Zhuo Zhang, Xianglin Shi

Faculty Publications

Carcinogenesis induced by environmental metal exposure is a major public health concern. The exact mechanisms underlying metal carcinogenesis remain elusive. In the past few decades, the relationship between metal-induced generation of reactive oxygen species (ROS) and the mechanism of metal carcinogenesis has been established. The carcinogenic process is a very complex one. In the early stage of metal carcinogenesis or cell transformation, high levels of ROS are oncogenic by causing DNA damage, genetic instability, epigenetic alteration, and metabolic reprogramming, leading to malignant transformation. In the second stage of metal carcinogenesis or the cancer development of metal-transformed cells, low levels of …

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Invited Review: Mesenchymal Progenitor Cells In Intramuscular Connective Tissue Development, Z. G. Miao, L. P. Zhang, X. Fu, Q. Y. Yang, M. J. Zhu, M. V. Dodson, M. Du Jul 2016

Invited Review: Mesenchymal Progenitor Cells In Intramuscular Connective Tissue Development, Z. G. Miao, L. P. Zhang, X. Fu, Q. Y. Yang, M. J. Zhu, M. V. Dodson, M. Du

Faculty Publications

© The Animal Consortium 2015. The abundance and cross-linking of intramuscular connective tissue contributes to the background toughness of meat, and is thus undesirable. Connective tissue is mainly synthesized by intramuscular fibroblasts. Myocytes, adipocytes and fibroblasts are derived from a common pool of progenitor cells during the early embryonic development. It appears that multipotent mesenchymal stem cells first diverge into either myogenic or non-myogenic lineages; non-myogenic mesenchymal progenitors then develop into the stromal-vascular fraction of skeletal muscle wherein adipocytes, fibroblasts and derived mesenchymal progenitors reside. Because non-myogenic mesenchymal progenitors mainly undergo adipogenic or fibrogenic differentiation during muscle development, strengthening progenitor …

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Stabilization In A Chemostat With Sampled And Delayed Measurements, Frédéric Mazenc, Jérome Harmand, Michael Malisoff Jul 2016

Stabilization In A Chemostat With Sampled And Delayed Measurements, Frédéric Mazenc, Jérome Harmand, Michael Malisoff

Faculty Publications

We study chemostat models with constant substrate input concentrations. We allow growth functions that are not necessarily monotone. The measurement is the substrate concentration, which is piecewise constant with a nonconstant delay, so only sampled observations are available. Under new conditions on the size of the delay and on the largest sampling interval, we solve the problem of asymptotically stabilizing a componentwise positive equilibrium point with the dilution rate as the control. We use a new Lyapunov approach.

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Three Distinct Glutamate Decarboxylase Genes In Vertebrates, Brian P. Grone, Karen P. Maruska Jul 2016

Three Distinct Glutamate Decarboxylase Genes In Vertebrates, Brian P. Grone, Karen P. Maruska

Faculty Publications

Gamma-aminobutyric acid (GABA) is a widely conserved signaling molecule that in animals has been adapted as a neurotransmitter. GABA is synthesized from the amino acid glutamate by the action of glutamate decarboxylases (GADs). Two vertebrate genes, GAD1 and GAD2, encode distinct GAD proteins: GAD67 and GAD65, respectively. We have identified a third vertebrate GAD gene, GAD3. This gene is conserved in fishes as well as tetrapods. We analyzed protein sequence, gene structure, synteny, and phylogenetics to identify GAD3 as a homolog of GAD1 and GAD2. Interestingly, we found that GAD3 was lost in the hominid lineage. Because of the importance …

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First Record Of The Non-Native Suckermouth Armored Catfish Hypostomus Cf. Niceforoi (Fowler 1943) (Siluriformes: Loricariidae) From Central America, Wilfredo A. Matamoros, Caleb D. Mcmahan, Carlos R. Mejia, Parker H. House, Jonathan W. Armbruster, Prosanta Chakrabarty Jul 2016

First Record Of The Non-Native Suckermouth Armored Catfish Hypostomus Cf. Niceforoi (Fowler 1943) (Siluriformes: Loricariidae) From Central America, Wilfredo A. Matamoros, Caleb D. Mcmahan, Carlos R. Mejia, Parker H. House, Jonathan W. Armbruster, Prosanta Chakrabarty

Occasional Papers of the Museum of Natural Science, Louisiana State University

We document the first record of Hypostomus cf. niceforoi in Central America. Two specimens of these suckermouth armored catfishes were collected in Lake Nicaragua (Nicaragua) and identified as H. cf. niceforoi. Hypostomus niceforoi is endemic to Andean streams of Colombia, Venezuela, Ecuador, and Peru. We hypothesize that its introduction in Central America is related to the aquarium trade, as is the case of other armored catfish species introductions.

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High Resolution Laser Mass Spectrometry Bioimaging, Kermit K. Murray, Chinthaka A. Seneviratne, Suman Ghorai Jul 2016

High Resolution Laser Mass Spectrometry Bioimaging, Kermit K. Murray, Chinthaka A. Seneviratne, Suman Ghorai

Faculty Publications

© 2016 Elsevier Inc. Mass spectrometry imaging (MSI) was introduced more than five decades ago with secondary ion mass spectrometry (SIMS) and a decade later with laser desorption/ionization (LDI) mass spectrometry (MS). Large biomolecule imaging by matrix-assisted laser desorption/ionization (MALDI) was developed in the 1990s and ambient laser MS a decade ago. Although SIMS has been capable of imaging with a moderate mass range at sub-micrometer lateral resolution from its inception, laser MS requires additional effort to achieve a lateral resolution of 10 μm or below which is required to image at the size scale of single mammalian cells. This …

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Ph-Dependent Dna Distortion And Repression Of Gene Expression By Pectobacterium Atrosepticum Pecs, Dinesh K. Deochand, Jacob K. Meariman, Anne Grove Jul 2016

Ph-Dependent Dna Distortion And Repression Of Gene Expression By Pectobacterium Atrosepticum Pecs, Dinesh K. Deochand, Jacob K. Meariman, Anne Grove

Faculty Publications

© 2016 American Chemical Society. Transcriptional activity is exquisitely sensitive to changes in promoter DNA topology. Transcription factors may therefore control gene activity by modulating the relative positioning of -10 and -35 promoter elements. The plant pathogen Pectobacterium atrosepticum, which causes soft rot in potatoes, must alter gene expression patterns to ensure growth in planta. In the related soft-rot enterobacterium Dickeya dadantii, PecS functions as a master regulator of virulence gene expression. Here, we report that P. atrosepticum PecS controls gene activity by altering promoter DNA topology in response to pH. While PecS binds the pecS promoter with high affinity …

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Phosphogenesis Associated With The Shuram Excursion: Petrographic And Geochemical Observations From The Ediacaran Doushantuo Formation Of South China, Huan Cui, Shuhai Xiao, Chuanming Zhou, Yongbo Peng, Alan J. Kaufman, Rebecca E. Plummer Jul 2016

Phosphogenesis Associated With The Shuram Excursion: Petrographic And Geochemical Observations From The Ediacaran Doushantuo Formation Of South China, Huan Cui, Shuhai Xiao, Chuanming Zhou, Yongbo Peng, Alan J. Kaufman, Rebecca E. Plummer

Faculty Publications

© 2016 Elsevier B.V. The Ediacaran Period witnessed one of the largest phosphogenic events in Earth's history. Coincidently, some phosphorite deposits in South China are associated with the largest-known carbon isotope negative excursion (i.e., Shuram Excursion), suggesting an intimate coupling of the biogeochemical carbon and phosphorous cycles. However, the geomicrobiological linkage between these anomalies remain poorly understood. In this study, we investigated the phosphorite samples from the uppermost Doushantuo Formation in South China. Carbon isotope compositions of authigenic calcite cements and nodules in the phosphorites are as low as –34‰ (VPDB). Petrographic and geochemical investigations indicate that the 13C-depleted carbonates …

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New "Light" For One-World Approach Toward Safe And Effective Control Of Animal Diseases And Insect Vectors From Leishmaniac Perspectives, Kwang Poo Chang, Bala K. Kolli, Ramesh B. Batchu, Hui Wen Chen, Larry Ming C. Chow, Robert Elliott, Jonathan F. Head, Chia Kwung Fan, Chen Hsiung Hung, Dar Der Ji, Zhao Rong Lun, Laura Manna, Yoshitsugu Matsumoto, Dennis K.P. Ng, Camila I. De Oliveira, Sayonara Melo, Yusuf Ozbel, Ahmet Özbilgin, Joseph Reynolds, Chizu Sanjoba, Shin Hong Shiao, Nang Yao Shih, Chi Wei Tsai, Maria Da Graça H. Vicente, Charles H. Barré, Petr Volf, Yueh Lung Wu, Chao Lan Yu, Xiao Nong Zhou Jul 2016

New "Light" For One-World Approach Toward Safe And Effective Control Of Animal Diseases And Insect Vectors From Leishmaniac Perspectives, Kwang Poo Chang, Bala K. Kolli, Ramesh B. Batchu, Hui Wen Chen, Larry Ming C. Chow, Robert Elliott, Jonathan F. Head, Chia Kwung Fan, Chen Hsiung Hung, Dar Der Ji, Zhao Rong Lun, Laura Manna, Yoshitsugu Matsumoto, Dennis K.P. Ng, Camila I. De Oliveira, Sayonara Melo, Yusuf Ozbel, Ahmet Özbilgin, Joseph Reynolds, Chizu Sanjoba, Shin Hong Shiao, Nang Yao Shih, Chi Wei Tsai, Maria Da Graça H. Vicente, Charles H. Barré, Petr Volf, Yueh Lung Wu, Chao Lan Yu, Xiao Nong Zhou

Faculty Publications

© 2016 The Author(s). Light is known to excite photosensitizers (PS) to produce cytotoxic reactive oxygen species (ROS) in the presence of oxygen. This modality is attractive for designing control measures against animal diseases and pests. Many PS have a proven safety record. Also, the ROS cytotoxicity selects no resistant mutants, unlike other drugs and pesticides. Photodynamic therapy (PDT) refers to the use of PS as light activable tumoricides, microbicides and pesticides in medicine and agriculture. Here we describe "photodynamic vaccination" (PDV) that uses PDT-inactivation of parasites, i.e. Leishmania as whole-cell vaccines against leishmaniasis, and as a universal carrier to …

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A New Genus And Species Of Blind Sleeper (Teleostei: Eleotridae) From Oaxaca, Mexico: First Obligate Cave Gobiiform In The Western Hemisphere, Stephen J. Walsh, Prosanta Chakrabarty Jul 2016

A New Genus And Species Of Blind Sleeper (Teleostei: Eleotridae) From Oaxaca, Mexico: First Obligate Cave Gobiiform In The Western Hemisphere, Stephen J. Walsh, Prosanta Chakrabarty

Faculty Publications

© 2016 by the American Society of Ichthyologists and Herpetologists. Caecieleotris morrisi, new genus and species of sleeper (family Eleotridae), is described from a submerged freshwater cave in a karst region of the northern portion of the State of Oaxaca, Mexico, Río Papaloapan drainage, Gulf of Mexico basin. The new species represents the first cave-adapted sleeper known from the Western Hemisphere and is one of only 13 stygobitic gobiiforms known worldwide, with all others limited in distribution to the Indo-Pacific region. The new taxon represents a third independent evolution of a hypogean lifestyle in sleepers, the others being two species …

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Louisiana Agriculture Summer, 2016, Lsu Agcenter Jul 2016

Louisiana Agriculture Summer, 2016, Lsu Agcenter

Louisiana Agriculture

No abstract provided.

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A Single Amino-Acid Substitution In The Sodium Transporter Hkt1 Associated With Plant Salt Tolerance, Akhtar Ali, Natalia Raddatz, Rashid Aman, Songmi Kim, Hyeong Cheol Park, Masood Jan, Dongwon Baek, Irfan Ullah Khan, Dong Ha Oh, Sang Yeol Lee, Ray A. Bressan, Keun Woo Lee, Albino Maggio, Jose M. Pardo, Hans J. Bohnert, Dae Jin Yun Jul 2016

A Single Amino-Acid Substitution In The Sodium Transporter Hkt1 Associated With Plant Salt Tolerance, Akhtar Ali, Natalia Raddatz, Rashid Aman, Songmi Kim, Hyeong Cheol Park, Masood Jan, Dongwon Baek, Irfan Ullah Khan, Dong Ha Oh, Sang Yeol Lee, Ray A. Bressan, Keun Woo Lee, Albino Maggio, Jose M. Pardo, Hans J. Bohnert, Dae Jin Yun

Faculty Publications

© 2016 American Society of Plant Biologists. All rights reserved. A crucial prerequisite for plant growth and survival is the maintenance of potassium uptake, especially when high sodium surrounds the root zone. The Arabidopsis HIGH-AFFINITY K+ TRANSPORTER1 (HKT1), and its homologs in other salt-sensitive dicots, contributes to salinity tolerance by removing Na+ from the transpiration stream. However, TsHKT1;2, one of three HKT1 copies in Thellungiella salsuginea, a halophytic Arabidopsis relative, acts as a K+transporter in the presence of Na+ in yeast (Saccharomyces cerevisiae). Amino-acid sequence comparisons indicated differences between TsHKT1;2 and most other published HKT1 sequences with respect to an …

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Perchlorate And Volatiles Of The Brine Of Lake Vida (Antarctica): Implication For The In Situ Analysis Of Mars Sediments, Fabien Kenig, Luoth Chou, Christopher P. Mckay, W. Andrew Jackson, Peter T. Doran, Alison E. Murray, Christian H. Fritsen Jul 2016

Perchlorate And Volatiles Of The Brine Of Lake Vida (Antarctica): Implication For The In Situ Analysis Of Mars Sediments, Fabien Kenig, Luoth Chou, Christopher P. Mckay, W. Andrew Jackson, Peter T. Doran, Alison E. Murray, Christian H. Fritsen

Faculty Publications

©2016. American Geophysical Union. All Rights Reserved. The cold (−13.4°C), cryoencapsulated, anoxic, interstitial brine of the >27 m thick ice of Lake Vida (Victoria Valley, Antarctica) contains 49 µg · L−1of perchlorate and 11 µg · L−1of chlorate. Lake Vida brine (LVBr) may provide an analog for potential oxychlorine-rich subsurface brine on Mars. LVBr volatiles were analyzed by solid-phase microextraction (SPME) gas chromatography–mass spectrometry (GC-MS) with two different SPME fibers. With the exception of volatile organic sulfur compounds, most other volatiles observed were artifacts produced in the GC injector when the thermal decomposition products of oxychlorines reacted with reduced carbon …

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Cobalt Chloride Treatment Used To Ablate The Lateral Line System Also Impairs The Olfactory System In Three Freshwater Fishes, Julie M. Butler, Karen E. Field, Karen P. Maruska Jul 2016

Cobalt Chloride Treatment Used To Ablate The Lateral Line System Also Impairs The Olfactory System In Three Freshwater Fishes, Julie M. Butler, Karen E. Field, Karen P. Maruska

Faculty Publications

© 2016 Butler et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Fishes use multimodal signals during both inter- and intra-sexual displays to convey information about their sex, reproductive state, and social status. These complex behavioral displays can include visual, auditory, olfactory, tactile, and hydrodynamic signals, and the relative role of each sensory channel in these complex multi-sensory interactions is a common focus of neuroethology. The mechanosensory lateral line system of fishes detects …

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Mitogen-Dependent Regulation Of Dusp1 Governs Erk And P38 Signaling During Early 3t3-L1 Adipocyte Differentiation, Bradley S. Ferguson, Heesun Nam, Jacqueline M. Stephens, Ron F. Morrison Jul 2016

Mitogen-Dependent Regulation Of Dusp1 Governs Erk And P38 Signaling During Early 3t3-L1 Adipocyte Differentiation, Bradley S. Ferguson, Heesun Nam, Jacqueline M. Stephens, Ron F. Morrison

Faculty Publications

© 2015 Wiley Periodicals, Inc. Knowledge concerning mechanisms that control proliferation and differentiation of preadipocytes is essential to our understanding of adipocyte hyperplasia and the development of obesity. Evidence has shown that temporal regulation of mitogen-activated protein kinase (MAPK) phosphorylation and dephosphorylation is critical for coupling extracellular stimuli to cellular growth and differentiation. Using differentiating 3T3-L1 preadipocytes as a model of adipocyte hyperplasia, we examined a role for dual-specificity phosphatase 1 (DUSP1) on the timely modulation of MAPK signaling during states of growth arrest, proliferation, and differentiation. Using real-time reverse transcription PCR (qRT-PCR), we report that DUSP1 is induced during …

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Geauxdock: Accelerating Structure-Based Virtual Screening With Heterogeneous Computing, Ye Fang, Yun Ding, Wei P. Feinstein, David M. Koppelman, Juana Moreno, Mark Jarrell, J. Ramanujam, Michal Brylinski Jul 2016

Geauxdock: Accelerating Structure-Based Virtual Screening With Heterogeneous Computing, Ye Fang, Yun Ding, Wei P. Feinstein, David M. Koppelman, Juana Moreno, Mark Jarrell, J. Ramanujam, Michal Brylinski

Faculty Publications

© 2016 Fang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Computational modeling of drug binding to proteins is an integral component of direct drug design. Particularly, structure-based virtual screening is often used to perform large-scale modeling of putative associations between small organic molecules and their pharmacologically relevant protein targets. Because of a large number of drug candidates to be evaluated, an accurate and fast docking engine is a critical element of …

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Comparative Transcriptome Analysis Of Resistant And Susceptible Common Bean Genotypes In Response To Soybean Cyst Nematode Infection, Shalu Jain, Kishore Chittem, Robert Brueggeman, Juan M. Osorno, Jonathan Richards, Berlin D. Nelson Jul 2016

Comparative Transcriptome Analysis Of Resistant And Susceptible Common Bean Genotypes In Response To Soybean Cyst Nematode Infection, Shalu Jain, Kishore Chittem, Robert Brueggeman, Juan M. Osorno, Jonathan Richards, Berlin D. Nelson

Faculty Publications

Soybean cyst nematode (SCN; Heterodera glycines Ichinohe) reproduces on the roots of common bean (Phaseolus vulgaris L.) and can cause reductions in plant growth and seed yield. The molecular changes in common bean roots caused by SCN infection are unknown. Identification of genetic factors associated with SCN resistance could help in development of improved bean varieties with high SCN resistance. Gene expression profiling was conducted on common bean roots infected by SCN HG type 0 using next generation RNA sequencing technology. Two pinto bean genotypes, PI533561 and GTS-900, resistant and susceptible to SCN infection, respectively, were used as RNA sources …

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Fine Mapping Of The Barley Chromosome 6h Net Form Net Blotch Susceptibility Locus, Jonathan Richards, Shiaoman Chao, Timothy Friesen, Robert Brueggeman Jul 2016

Fine Mapping Of The Barley Chromosome 6h Net Form Net Blotch Susceptibility Locus, Jonathan Richards, Shiaoman Chao, Timothy Friesen, Robert Brueggeman

Faculty Publications

Net form net blotch, caused by the necrotrophic fungal pathogen Pyrenophora teres f. teres, is a destructive foliar disease of barley with the potential to cause significant yield loss in major production regions throughout the world. The complexity of the host-parasite genetic interactions in this pathosystem hinders the deployment of effective resistance in barley cultivars, warranting a deeper understanding of the interactions. Here, we report on the high-resolution mapping of the dominant susceptibility locus near the centromere of chromosome 6H in the barley cultivars Rika and Kombar, which are putatively targeted by necrotrophic effectors from P. teres f. teres isolates …

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Meta-Analysis Of 49 549 Individuals Imputed With The 1000 Genomes Project Reveals An Exonic Damaging Variant In Angptl4 Determining Fasting Tg Levels, Elisabeth M. Van Leeuwen, Aniko Sabo, Joshua C. Bis, Jennifer E. Huffman, Ani Manichaikul, Albert V. Smith, Mary F. Feitosa, Serkalem Demissie, Peter K. Joshi, Qing Duan, Jonathan Marten, Jan B. Van Klinken, Ida Surakka, Ilja M. Nolte, Weihua Zhang, Hamdi Mbarek, Ruifang Li-Gao, Stella Trompet, Niek Verweij, Evangelos Evangelou, Leo Pekka Lyytikäinen, Bamidele O. Tayo, Joris Deelen, Peter J. Van Der Most, Sander W. Van Der Laan, Dan E. Arking, Alanna Morrison, Abbas Dehghan, Oscar H. Franco, Albert Hofman, Fernando Rivadeneira, Eric J. Sijbrands, Andre G. Uitterlinden Jul 2016

Meta-Analysis Of 49 549 Individuals Imputed With The 1000 Genomes Project Reveals An Exonic Damaging Variant In Angptl4 Determining Fasting Tg Levels, Elisabeth M. Van Leeuwen, Aniko Sabo, Joshua C. Bis, Jennifer E. Huffman, Ani Manichaikul, Albert V. Smith, Mary F. Feitosa, Serkalem Demissie, Peter K. Joshi, Qing Duan, Jonathan Marten, Jan B. Van Klinken, Ida Surakka, Ilja M. Nolte, Weihua Zhang, Hamdi Mbarek, Ruifang Li-Gao, Stella Trompet, Niek Verweij, Evangelos Evangelou, Leo Pekka Lyytikäinen, Bamidele O. Tayo, Joris Deelen, Peter J. Van Der Most, Sander W. Van Der Laan, Dan E. Arking, Alanna Morrison, Abbas Dehghan, Oscar H. Franco, Albert Hofman, Fernando Rivadeneira, Eric J. Sijbrands, Andre G. Uitterlinden

Faculty Publications

Background So far, more than 170 loci have been associated with circulating lipid levels through genomewide association studies (GWAS). These associations are largely driven by common variants, their function is often not known, and many are likely to be markers for the causal variants. In this study we aimed to identify more new rare and low-frequency functional variants associated with circulating lipid levels. Methods We used the 1000 Genomes Project as a reference panel for the imputations of GWAS data from ~60 000 individuals in the discovery stage and ~90 000 samples in the replication stage. Results Our study resulted …

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Quantifying The Spatiotemporal Dynamics In A Chorus Frog (Pseudacris) Hybrid Zone Over 30 Years, Kristin N. Engebretsen, Lisa N. Barrow, Eric N. Rittmeyer, Jeremy M. Brown, Emily Moriarty Lemmon Jul 2016

Quantifying The Spatiotemporal Dynamics In A Chorus Frog (Pseudacris) Hybrid Zone Over 30 Years, Kristin N. Engebretsen, Lisa N. Barrow, Eric N. Rittmeyer, Jeremy M. Brown, Emily Moriarty Lemmon

Faculty Publications

© 2016 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd. Although theory suggests that hybrid zones can move or change structure over time, studies supported by direct empirical evidence for these changes are relatively limited. We present a spatiotemporal genetic study of a hybrid zone between Pseudacris nigrita and P. fouquettei across the Pearl River between Louisiana and Mississippi. This hybrid zone was initially characterized in 1980 as a narrow and steep “tension zone,” in which hybrid populations were inferior to parentals and were maintained through a balance between selection and dispersal. We reanalyzed historical tissue …

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Identiication Of Essential Arginine Residues Of Escherichia Coli Deda/Tvp38 Family Membrane Proteins Yqja And Yghb, Sujeet Kumar, Cersten L. Bradley, Patience Mukashyaka, William T. Doerrler Jul 2016

Identiication Of Essential Arginine Residues Of Escherichia Coli Deda/Tvp38 Family Membrane Proteins Yqja And Yghb, Sujeet Kumar, Cersten L. Bradley, Patience Mukashyaka, William T. Doerrler

Faculty Publications

© 2016 FEMS. Escherichia coli DedA/Tvp38 family proteins YghB and YqjA are putative membrane transporters with 62% amino acid identity and overlapping functions. An E. coli strain (BC202) with nonpolar ΔyghB and ΔyqjA mutations displays cell-division defects and temperature sensitivity and is sensitive to antibiotics and alkaline pH. In this study, we performed site-directed mutagenesis on conserved, charged amino acids of YqjA and YghB. We discovered two conserved predicted membrane-embedded arginines (R130 and R136) that are critical for function in both proteins as deined by their ability to complement BC202 phenotypes, when expressed from a plasmid. Lysine can substitute for …

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Be-Breeder - Learning: A New Tool For Teaching And Learning Plant Breeding Principles, Roberto Fritsche-Neto, Filipe Inácio Matias Jul 2016

Be-Breeder - Learning: A New Tool For Teaching And Learning Plant Breeding Principles, Roberto Fritsche-Neto, Filipe Inácio Matias

Faculty Publications

The Be-Breeder application is an on-line tool constructed through the R software for the purpose of assisting in some of the main genetic and statistical analyses related to the area of plant breeding. In addition, Be-Breeder provides a section called “Learning”, which in a simple click-point manner allows explanation of theories related to the effect of inbreeding, population structure, qualitative and quantitative traits, heterosis, population size, effect of selection, and composition of hybrids. Be-Breeder is available for network use on the website of the Allogamous Plant Breeding Laboratory (Laboratório de Melhoramento de Plantas Alógamas) of ESALQ-USP through the link: http:// …

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Population Genomics Related To Adaptation In Elite Oat Germplasm, Kathy Esvelt Klos, Yung Fen Huang, Wubishet A. Bekele, Don E. Obert, Ebrahiem Babiker, Aaron D. Beattie, Åsmund Bjørnstad, J. Michael Bonman, Martin L. Carson, Shiaoman Chao, Belaghihalli N. Gnanesh, Irene Griffiths, Stephen A. Harrison, Catherine J. Howarth, Gongshe Hu, Amir Ibrahim, Emir Islamovic, Eric W. Jackson, Jean Luc Jannink, Frederic L. Kolb, Michael S. Mcmullen, Jennifer Mitchell Fetch, J. Paul Murphy, Herbert W. Ohm, Howard W. Rines, Brian G. Rossnagel, Jessica A. Schlueter, Mark E. Sorrells, Charlene P. Wight, Weikai Yan, Nicholas A. Tinker Jul 2016

Population Genomics Related To Adaptation In Elite Oat Germplasm, Kathy Esvelt Klos, Yung Fen Huang, Wubishet A. Bekele, Don E. Obert, Ebrahiem Babiker, Aaron D. Beattie, Åsmund Bjørnstad, J. Michael Bonman, Martin L. Carson, Shiaoman Chao, Belaghihalli N. Gnanesh, Irene Griffiths, Stephen A. Harrison, Catherine J. Howarth, Gongshe Hu, Amir Ibrahim, Emir Islamovic, Eric W. Jackson, Jean Luc Jannink, Frederic L. Kolb, Michael S. Mcmullen, Jennifer Mitchell Fetch, J. Paul Murphy, Herbert W. Ohm, Howard W. Rines, Brian G. Rossnagel, Jessica A. Schlueter, Mark E. Sorrells, Charlene P. Wight, Weikai Yan, Nicholas A. Tinker

Faculty Publications

Six hundred thirty five oat (Avena sativa L.) lines and 4561 single-nucleotide polymorphism (SNP) loci were used to evaluate population structure, linkage disequilibrium (LD), and genotype-phenotype association with heading date. The first five principal components (PCs) accounted for 25.3% of genetic variation. Neither the eigenvalues of the first 25 PCs nor the cross-validation errors from K = 1 to 20 model-based analyses suggested a structured population. However, the PC and K = 2 model-based analyses supported clustering of lines on spring oat vs. southern United States origin, accounting for 16% of genetic variation (p < 0.0001). Single-locus F-statistic (FST) in the highest 1% of the distribution suggested linkage groups that may be differentiated between the two population subgroups. Population structure and kinship-corrected LD of r2 = 0.10 was observed at an average pairwise distance of 0.44 cM (0.71 and 2.64 cM within spring and southern oat, respectively). On most linkage groups LD decay was slower within southern lines than within the spring lines. A notable exception was found on linkage group Mrg28, where LD decay was substantially slower in the spring subpopulation. It is speculated that this may be caused by a heterogeneous translocation event on this chromosome. Association with heading date was most consistent across location-years on linkage groups Mrg02, Mrg12, Mrg13, and Mrg24.

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Population Genomics Related To Adaptation In Elite Oat Germplasm, Kathy Esvelt Klos, Yung Fen Huang, Wubishet A. Bekele, Don E. Obert, Ebrahiem Babiker, Aaron D. Beattie, Åsmund Bjørnstad, J. Michael Bonman, Martin L. Carson, Shiaoman Chao, Belaghihalli N. Gnanesh, Irene Griffiths, Stephen A. Harrison, Catherine J. Howarth, Gongshe Hu, Amir Ibrahim, Emir Islamovic, Eric W. Jackson, Jean Luc Jannink, Frederic L. Kolb, Michael S. Mcmullen, Jennifer Mitchell Fetch, J. Paul Murphy, Herbert W. Ohm, Howard W. Rines, Brian G. Rossnagel, Jessica A. Schlueter, Mark E. Sorrells, Charlene P. Wight, Weikai Yan, Nicholas A. Tinker Jul 2016

Population Genomics Related To Adaptation In Elite Oat Germplasm, Kathy Esvelt Klos, Yung Fen Huang, Wubishet A. Bekele, Don E. Obert, Ebrahiem Babiker, Aaron D. Beattie, Åsmund Bjørnstad, J. Michael Bonman, Martin L. Carson, Shiaoman Chao, Belaghihalli N. Gnanesh, Irene Griffiths, Stephen A. Harrison, Catherine J. Howarth, Gongshe Hu, Amir Ibrahim, Emir Islamovic, Eric W. Jackson, Jean Luc Jannink, Frederic L. Kolb, Michael S. Mcmullen, Jennifer Mitchell Fetch, J. Paul Murphy, Herbert W. Ohm, Howard W. Rines, Brian G. Rossnagel, Jessica A. Schlueter, Mark E. Sorrells, Charlene P. Wight, Weikai Yan, Nicholas A. Tinker

Faculty Publications

Six hundred thirty five oat ( L.) lines and 4561 single-nucleotide polymorphism (SNP) loci were used to evaluate population structure, linkage disequilibrium (LD), and genotype-phenotype association with heading date. The first five principal components (PCs) accounted for 25.3% of genetic variation. Neither the eigenvalues of the first 25 PCs nor the cross-validation errors from = 1 to 20 model-based analyses suggested a structured population. However, the PC and = 2 model-based analyses supported clustering of lines on spring oat vs. southern United States origin, accounting for 16% of genetic variation ( < 0.0001). Single-locus -statistic () in the highest 1% of the distribution suggested linkage groups that may be differentiated between the two population subgroups. Population structure and kinship-corrected LD of = 0.10 was observed at an average pairwise distance of 0.44 cM (0.71 and 2.64 cM within spring and southern oat, respectively). On most linkage groups LD decay was slower within southern lines than within the spring lines. A notable exception was found on linkage group Mrg28, where LD decay was substantially slower in the spring subpopulation. It is speculated that this may be caused by a heterogeneous translocation event on this chromosome. Association with heading date was most consistent across location-years on linkage groups Mrg02, Mrg12, Mrg13, and Mrg24.

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Environmental Context For The Terminal Ediacaran Biomineralization Of Animals, H. Cui, A. J. Kaufman, S. Xiao, S. Peek, H. Cao, X. Min, Y. Cai, Z. Siegel, X. M. Liu, Y. Peng, J. D. Schiffbauer, A. J. Martin Jul 2016

Environmental Context For The Terminal Ediacaran Biomineralization Of Animals, H. Cui, A. J. Kaufman, S. Xiao, S. Peek, H. Cao, X. Min, Y. Cai, Z. Siegel, X. M. Liu, Y. Peng, J. D. Schiffbauer, A. J. Martin

Faculty Publications

© 2016 John Wiley & Sons Ltd In terminal Ediacaran strata of South China, the onset of calcareous biomineralization is preserved in the paleontological transition from Conotubus to Cloudina in repetitious limestone facies of the Dengying Formation. Both fossils have similar size, funnel-in-funnel construction, and epibenthic lifestyle, but Cloudina is biomineralized, whereas Conotubus is not. To provide environmental context for this evolutionary milestone, we conducted a high-resolution elemental and stable isotope study of the richly fossiliferous Gaojiashan Member. Coincident with the first appearance of Cloudina is a significant positive carbonate carbon isotope excursion (up to +6‰) and an increase in …

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Editorial: Ethylene’S Role In Plant Mineral Nutrition, Francisco J. Romera, Aaron P. Smith, Rafael Pérez-Vicente Jun 2016

Editorial: Ethylene’S Role In Plant Mineral Nutrition, Francisco J. Romera, Aaron P. Smith, Rafael Pérez-Vicente

Faculty Publications

No abstract provided.

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Dynamics Of Resprouting And Forest Regeneration Following Anthropogenic Land Use In The Central Amazon Basin, Scott Lawrence Kosiba Jun 2016

Dynamics Of Resprouting And Forest Regeneration Following Anthropogenic Land Use In The Central Amazon Basin, Scott Lawrence Kosiba

LSU Doctoral Dissertations

Tree mortality is increasing with the effects of climate change and drought across the Amazon Basin while intense fires are becoming more prevalent. Tropical moist forest trees generally lack adaptations that protect against mortality during an intense fire, so anthropogenic burning typically kills high percentages of trees. Following disturbances where prescribed burning is used to limit woody encroachment and to fertilize the soil, abandoned land in central Amazonia becomes dominated by the pioneer tree genus, Vismia. Although the mechanisms by which Vismia comes to dominate previously-burned areas are not known, previous studies on anthropogenic land use and forest succession …

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