Digital Commons Network^™

3d Modeling And Animation Of The Temporomandibular Joint (Tmj) Of A Human Male With Implications For The Study Of Tmj Dysfunction, Breigh Sonnier

Honors Capstones

No abstract provided.

The Development And Role Of Diagnostic Imaging And Three-Dimensional Printing Technologies In Anthropology And Medicine, William Long

Honors Capstones

No abstract provided.

On The Use Of Hertz’S Contact Stress For A Deformable Roller On A Half Space, Trent M. Andrus

Honors Capstones

No abstract provided.

An Investigation Of Maltose Transport System Induction In The Rugose Phase Variant Of Human Pathogen Vibrio Vulnificus, Hira Hasan

Honors Capstones

No abstract provided.

A Comparative Study Of Tooth Wear In Contemporary Us And Non-Us Populations To Evaluate The Validity Of Use In Estimating Region Of Origin, Amelie Marie Juneau

Honors Capstones

No abstract provided.

Artemisia Scoparia Reduces The Effects Of Tnfα-Induced Lipolysis In Murine Adipocytes, Ruth Dunn

Honors Capstones

No abstract provided.

The Fate Of Soil Carbon In Louisiana’S Eroding Coastal Wetlands And Potential Impact On Future Climate, Amanda Fontenot

Honors Capstones

No abstract provided.

Vacuum-Operated Microfluidic Device For Colorimetric Determination Of Sperm Motility In Aquatic Species, Faiz Alam

Honors Capstones

No abstract provided.

Insufficient Dha Intake In Pregnant And Lactating Women Of Baton Rouge, Louisiana: Further Nutrition Education Needed, Zoe Wilhelm

Honors Capstones

No abstract provided.

Analysis Of Young Alu Elements In The Squirrel Monkey (Saimiri) Lineage For Use As Species-Indicative Molecular Markers, Michael W. Denham

Honors Capstones

No abstract provided.

Efficacy Of Compound X (Bedoukian Research, Inc.) On Reducing Fecal Egg Count In Lambs, Mary M. France

Honors Capstones

No abstract provided.

Pore-Scale Analysis Of Interfacial Instabilities And Impact Of Heterogeneity On Relative Permeability By Lattice Boltzmann Method, Zhipeng Zhu

LSU Master's Theses

Interfacial instabilities occur often during immiscible fluid flow through porous media and their understanding is essential for waterflooding operations or other oil recovery processes. Although many studies including experimental and numerical have been done to reproduce and analyze the interfacial instabilities in porous median, there is still significant knowledge gap in fundamental understanding of these flow instabilities at the pore-scale. In order to better understand the interfacial instabilities phenomenon, the pore-scale simulations are performed. In this study, Lattice Boltzmann Method is used to simulate two different types of interfacial instabilities: viscous fingering and capillary fingering in irregular sphere packs by …

Artificial Recharge Of Groundwater As A Management Tool For The Kabul Basin, Afghanistan, Mohammad Farid Masoom

LSU Master's Theses

Decades of war and political instability, consecutive droughts, population increase and displacement, caused serious infrastructural damages to water resources of Afghanistan. The main source of water supply for people in Afghanistan is groundwater. However, over-exploitation of groundwater has led to groundwater level declines in most parts of the country. Kabul, the largest city of Afghanistan, is the capital city with a population of 4.5 million and the fifth fastest-growing city in the world. The city has observed groundwater level declines of 5-10 meters (m) since 1980. Decline of about 30 m has also been observed in one of the monitoring …

Silica-Conjugated Polymer Hybrid Fluorescent Nanoparticles: Preparation By Surface-Initiated Polymerization And Spectroscopic Studies, Sourav Chatterjee, Tony E. Karam, Cornelia Rosu, Chun Han Wang, Sang Gil Youm, Xin Li, Changwoo Do, Yaroslav Losovyj, Paul S. Russo, Louis H. Haber, Evgueni E. Nesterov

Faculty Publications

© 2018 American Chemical Society. Organic/inorganic hybrid nanoscale materials possess fascinating optical, electronic, magnetic, and catalytic properties that are promising for a variety of practical applications. Such properties can be dramatically affected by the hierarchical structure and molecular organization in the nanomaterials. Herein, we employed surface-initiated Kumada catalyst-transfer polymerization to prepare hybrid materials consisting of shells of conjugated polymers (CPs) - polythiophene or poly(p-phenylene) - and their block copolymers covalently attached to the surface of silica nanoparticles. Because of the controlled chain-growth mechanism of surface-initiated polymerization, we obtained structurally well-defined CP blocks in the diblock copolymer shells, which produced distinct …

Role Of Mucin 19 In The Respiratory Tract, Kaitlin Mcbride

LSU Master's Theses

Human metapneumovirus (HMPV) is a negative sense, single stranded RNA virus belonging to the Pneumoviridae family, and represents an important pathogen that causes severe respiratory disease worldwide. There is currently no vaccine against HMPV, so it is important to study the aspects of the immune response induced by HMPV. Because infiltration of mucus is a hallmark of HMPV infection, it is warranted to study the role of mucus in the disease process. Mucin proteins make up the major component of mucus and can be found within the airway and lungs. Previous work from our laboratory demonstrated a high upregulation of …

Emmanuel Levinas And The Meaning Of Ecological Responsibility, Joe Matthew Larios

LSU Master's Theses

Recent work in eco-phenomenology has often tried to find a way to situate Emmanuel Levinas’s ethical philosophy in a way that would be productive for environmental ethical concerns. This has often proved difficult due to the anthropocentrism of Levinas’s philosophy and the sometimes inconsistent interpretations of what the face of the Other signifies and whether it should be understood as perceptually present to the one who “sees” it in any way. This, combined with a general lack of engagement with Levinas’s writings on politics, has often made an ecological interpretation of Levinas difficult or awkward.

In this thesis, I try …

The Incremental Validity Of Parent-Reported Executive Functioning In Attention-Deficit/Hyperactivity Disorders And Reading Achievement, Ilayna Krysten Mehrtens

LSU Master's Theses

Attention-Deficit/Hyperactivity Disorder (ADHD) is a commonly diagnosed neuropsychological disorder in childhood. Children with ADHD are at an increased risk for comorbid learning disorders, particularly in reading. Attempts to understand the factors that contribute to the high co-occurrence of these disorders have identified Executive Functioning (EF) as a potential explanatory mechanism for this relationship. However, previous findings regarding the role of EF have been mixed. Additionally, much of the research regarding the influence of EF on reading achievement among children with ADHD has been limited to performance-based measures of EF. Subsequently, there is little research regarding the relative influence of behavioral …

Higher Energy Gap Control Of Fluorescence In Conjugated Polymers, Chien-Hung Chiang

LSU Doctoral Dissertations

Chemo- and biosensors based on fluorescent conjugated polymer benefit from greater detection sensitivity due to amplification of the electronic perturbations produced by analyte binding. This amplification stems from the exciton-transporting properties of conjugated polymers. A conventional design paradigm relies on the analyte binding events which generate sites of lower energy relative to the polymer energy: either fluorescence quenching sites (turn-off sensors) or bathochromically shifted fluorophores (turn-on sensors). In both type sensors, the excitons migrate to the lower-energy site created by analyte binding.

This dissertation primarily focused the investigation of an alternative paradigm when analyte binding creates higher energy gap sites …

R1 Retrotransposons In Drosophila Melanogaster Are Transcribed By Rna Polymerase I Upon Heat Shock, Himanshu Shekhar Raje

LSU Doctoral Dissertations

The ribosomal RNA genes of Drosophila melanogaster reside within centromere-proximal nucleolar organizers on both the X and Y chromosomes. Each locus contains between 200-300 tandem repeat rDNA units that encode 18S, 5.8S, and 28S ribosomal RNAs (rRNAs) for ribosome biogenesis. In arthropods like Drosophila, about 60% of rDNA genes are inserted with R1 and/or R2 retrotransposons at specific sites within the 28S regions; these units likely fail to produce functional 28S rRNA. We showed previously that R2 expression increases upon nucleolar stress caused by the loss of a ribosome assembly factor, the Nucleolar Phosphoprotein of 140 kDa (Nopp140). Here …

Influence Of Black Mangrove Expansion On Salt Marsh Faunal Communities Of Eastern Coastal Louisiana, Christina Powell

LSU Master's Theses

The salt marshes along the Gulf of Mexico provide a critical habitat for many species, but their spatial distribution is changing, because Avicennia germinans (black mangroves) are expanding due to warmer winters. Currently, little is known about how A. germinans are used as habitat providing food and refuge for aquatic fauna. Therefore, the overall goal of this study was to determine how A.germinans expansion into the Spartina alterniflora (smooth cordgrass) marshes of Louisiana’s Mississippi River delta plain affects salt marsh-dependent organisms. This study analyzed three habitat types: Spartina-dominated, Avicennia-dominated, and a mix of the two, focusing on habitat use and …

Determining Growth Characteristics And Control Programs For Nealley's Sprangletop (Leptochloa Nealleyi Vasey), Trace Buck

LSU Master's Theses

ABSTRACT

Research was conducted at the LSU AgCenter Dean Lee Research and Extension center near Alexandria, La in 2016 and 2017 to evaluate the growth characteristics and control of Nealley’s sprangletop. Nealley’s sprangletop is a relatively new weed with little research available to understand its growth habit and effective control strategies.

Nealley’s sprangletop undergoes a more drastic height increase of 212 to 742 mm, 4 to 6 WAE than Amazon sprangletop 377 to 612 mm in the same time frame. Averaged across harvest interval tiller and leaf number of Nealley’s sprangletop was approximately 50 and 40% less than Amazon sprangletop. …

Characteristics Associated With Improvements In Health Among Community Mental Health Clients With Thought Disorders Receiving Co-Located Primary Care Services, Mary Elizabeth Heintz

LSU Master's Theses

Individuals with serious mental illness (SMI) are disproportionately impacted by preventable physical health conditions, which put them at risk for premature mortality. Integrated primary and behavioral health care (PBHC) programs have demonstrated promise in treating comorbid physical and mental health conditions, common to individuals diagnosed with SMI. The current study focused on individuals with thought disorders (i.e., schizophrenia, schizoaffective disorder, and brief psychotic disorder), as those diagnosed are more likely to be retained in care. Treatment retention is especially important, as adherence slows down the progression of psychiatric symptoms and physical health diseases. Extant research has focused on evaluation of …

Characterizing The Physiological Role Of Inward Rectifier Potassium (Kir) Channels In Tick Salivary Gland Function, Zhilin Li

LSU Master's Theses

The tick salivary gland is a critical tissue that enables blood feeding, maintenance of the ionic gradients, and facilitates pathogen transmission. Therefore, the broad objective of this investigation was to leverage pharmacological approaches to investigate the role of potassium ion channels to salivary gland function of Amblyomma americanum in an effort to identify a tractable target site for therapeutic development.

Data collected in Chapter 2 clearly illustrated that the A. americanum salivary gland is reliant upon inward rectifier potassium (Kir) channels for fluid secretion, which was similar to previous work performed by our laboratory on Drosophila salivary gland. Therefore, the …

Transmission Potential Of Rickettsia Felis Through Cutaneous Inoculation Of Infectious Flea Feces, Kelsey Porter Legendre

LSU Master's Theses

Rickettsia felis, the causative agent of flea-borne spotted fever, is an emerging pathogen of the transitional group Rickettsiae and an important cause of febrile illness in Africa. Since the organism’s original discovery in the early 1990s, much research has been directed towards elucidating transmission mechanisms within the believed primary host and reservoir, the cat flea (Ctenocephalides felis). However, while a growing number of human cases are being reported throughout the world, a definitive transmission mechanism from arthropod host to vertebrate host resulting in clinical disease has not been found. Several possible mechanisms, including bite of infected arthropods …

General Stochastic Integral And Itô Formula With Application To Stochastic Differential Equations And Mathematical Finance, Jiayu Zhai

LSU Doctoral Dissertations

A general stochastic integration theory for adapted and instantly independent stochastic processes arises when we consider anticipative stochastic differential equations. In Part I of this thesis, we conduct a deeper research on the general stochastic integral introduced by W. Ayed and H.-H. Kuo in 2008. We provide a rigorous mathematical framework for the integral in Chapter 2, and prove that the integral is well-defined. Then a general Itô formula is given. In Chapter 3, we present an intrinsic property, near-martingale property, of the general stochastic integral, and Doob-Meyer's decomposition for near-submartigales. We apply the new stochastic integration theory to several …

Synthesis, Characterization, And Assessment Of Cationic Polypeptoids Toward Gene Delivery And Development Of Air Stable N-Substituted N-Thiocarboxyanhydrides, Jessica Michelle Simpson

LSU Doctoral Dissertations

Peptoids are a class of peptidomimetic polymers, which have attracted much attention over the years. Due to their structural similarity to peptides, this group of polymers affords good biocompatibility making them of interest for biomedical applications. This dissertation is largely about the design, synthesis, and characterization of cationic polypeptoids for biological applications, particularly nonviral gene delivery. The dissertation will also cover the development, characterization, and polymerization behavior of a new, air stable N-thiocarboxyanhydride (NTA) monomer.

Introducing functionality, such as small biomolecules and organic compounds can provide distinctive properties to the polymers. Chapter 1 introduces gene therapy and concepts pertinent …

A Single Fungal Map Kinase Controls Plant Cell-To-Cell Invasion By The Rice Blast Fungus, Wasin Sakulkoo, Miriam Osés-Ruiz, Ely Oliveira Garcia, Darren M. Soanes, George R. Littlejohn, Christian Hacker, Ana Correia, Barbara Valent, Nicholas J. Talbot

Faculty Publications

Blast disease destroys up to 30% of the rice crop annually and threatens global food security. The blast fungus Magnaporthe oryzae invades plant tissue with hyphae that proliferate and grow from cell to cell, often through pit fields, where plasmodesmata cluster. We showed that chemical genetic inhibition of a single fungal mitogen-activated protein (MAP) kinase, Pmk1, prevents M. oryzae from infecting adjacent plant cells, leaving the fungus trapped within a single plant cell. Pmk1 regulates expression of secreted fungal effector proteins implicated in suppression of host immune defenses, preventing reactive oxygen species generation and excessive callose deposition at plasmodesmata. Furthermore, …

An Analysis Of Alu Elements In Baboons, Cody James Steely

LSU Doctoral Dissertations

Transposable elements compose a large portion of mammalian genomes and are estimated to make up anywhere from ~45% - ~70% of the human genome. Alu elements are primate-specific retrotransposons that are found in high copy number (> 1 million copies) and are spread throughout the genome. These elements are the most commonly repeated sequence in the human genome and have contributed to a number of disease states in humans. Alu elements are useful markers for population genetics and phylogenetics and have proven valuable in understanding difficult to determine relationships between species and within populations.

Baboons (genus Papio) are spread throughout …

Fast Magic-Angle-Spinning 19F Spin Exchange Nmr For Determining Nanometer 19F-19F Distances In Proteins And Pharmaceutical Compounds, Matthias Roos, Tuo Wang, Alexander A. Shcherbakov, Mei Hong

Faculty Publications

© 2018 American Chemical Society. Internuclear distances measured using NMR provide crucial constraints of three-dimensional structures but are often restricted to about 5 Å due to the weakness of nuclear-spin dipolar couplings. For studying macromolecular assemblies in biology and materials science, distance constraints beyond 1 nm will be extremely valuable. Here we present an extensive and quantitative analysis of the feasibility of 19F spin exchange NMR for precise and robust measurements of interatomic distances up to 1.6 nm at a magnetic field of 14.1 T, under 20-40 kHz magic-angle spinning (MAS). The measured distances are comparable to those achievable from …

A Study Of The Lived Experience Of African American Males Who Transition From Out-Of-Home Care To Postsecondary Education, Marvin Cain Alexander

LSU Doctoral Dissertations

While the literature is replete with studies of the factors contributing to the failure and social deviance of African American males, few qualitative studies have been conducted to determine the factors that support the success of African American males, and virtually none have focused on the transition of African American males from out-of-home care to postsecondary educational institutions. Despite the challenges faced preceding and during out-of-home care, African American males can transition to postsecondary educational institutions. There is a need to understand why some African American males who experience out-of-home care can accomplish this while others cannot. It is imperative …