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Causes And Characteristics Of Electrical Resistivity Variability In Shallow (<4 M) Soils In Taylor Valley, East Antarctica, W. S. Gutterman, P. T. Doran, R. A. Virginia, J. E. Barrett, K. F. Myers, S. M. Tulaczyk, N. T. Foley, J. A. Mikucki, H. A. Dugan, D. J. Grombacher, T. S. Bording, E. Auken Feb 2023

Causes And Characteristics Of Electrical Resistivity Variability In Shallow (<4 M) Soils In Taylor Valley, East Antarctica, W. S. Gutterman, P. T. Doran, R. A. Virginia, J. E. Barrett, K. F. Myers, S. M. Tulaczyk, N. T. Foley, J. A. Mikucki, H. A. Dugan, D. J. Grombacher, T. S. Bording, E. Auken

Faculty Publications

Airborne electromagnetic surveys collected in December 2011 and November 2018 and three soil sampling transects were used to analyze the spatial heterogeneity of shallow (< 4 m) soil properties in lower Taylor Valley (TV), East Antarctica. Soil resistivities from 2011 to 2018 ranged from ∼33 Ωm to ∼3,500 Ωm with 200 Ωm assigned as an upper boundary for brine-saturated sediments. Elevations below ∼50 m above sea level (masl) typically exhibit the lowest resistivities with resistivity increasing at high elevations on steeper slopes. Soil water content was empirically estimated from electrical resistivities using Archie's Law and range from ∼< 1% to ∼68% by volume. An increase in silt- and clay-sized particles at low elevations increases soil porosity but decreases hydraulic conductivity, promoting greater residence times of soil water at low elevations near Lake Fryxell. Soil resistivity variability between 2011 and 2018 shows soils at different stages of soil freeze-thaw cycles, which are caused predominantly by solar warming of soils as opposed to air temperature. This study furthers the understanding of the hydrogeologic structure of the shallow subsurface in TV and identifies locations of soils that are potentially prone to greater rates of thaw and resulting ecosystem homogenization of soil properties from projected increases in hydrological connectivity across the region over the coming decades.

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Appraisal Of Clinical Care Practices For Child Obesity Treatment. Part Ii: Comorbidities, Asheley C. Skinner, Amanda E. Staiano, Sarah C. Armstrong, Shari L. Barkin, Sandra G. Hassink, Jennifer E. Moore, Jennifer S. Savage, Helene Vilme, Ashley E. Weedn, Janice Liebhart, Jeanne Lindros, Eileen M. Reilly Feb 2023

Appraisal Of Clinical Care Practices For Child Obesity Treatment. Part Ii: Comorbidities, Asheley C. Skinner, Amanda E. Staiano, Sarah C. Armstrong, Shari L. Barkin, Sandra G. Hassink, Jennifer E. Moore, Jennifer S. Savage, Helene Vilme, Ashley E. Weedn, Janice Liebhart, Jeanne Lindros, Eileen M. Reilly

Population and Public Health Science Faculty Publications

The objective of this technical report is to provide clinicians with actionable evidence-based information upon which to make treatment decisions. In addition, this report will provide an evidence base on which to inform clinical practice guidelines for the management and treatment of overweight and obesity in children and adolescents. To this end, the goal of this report was to identify all relevant studies to answer 2 overarching key questions: (KQ1) “What are effective clinically based treatments for obesity?” and (KQ2) “What is the risk of comorbidities among children with obesity?” See Appendix 1 for the conceptual framework and a priori …

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Envirome-Wide Associations Enhance Multi-Year Genome-Based Prediction Of Historical Wheat Breeding Data, Germano Costa-Neto, Leonardo Crespo-Herrera, Nick Fradgley, Keith Gardner, Alison R. Bentley, Susanne Dreisigacker, Roberto Fritsche-Neto, Osval A. Montesinos-López, Jose Crossa Feb 2023

Envirome-Wide Associations Enhance Multi-Year Genome-Based Prediction Of Historical Wheat Breeding Data, Germano Costa-Neto, Leonardo Crespo-Herrera, Nick Fradgley, Keith Gardner, Alison R. Bentley, Susanne Dreisigacker, Roberto Fritsche-Neto, Osval A. Montesinos-López, Jose Crossa

Faculty Publications

Linking high-throughput environmental data (enviromics) to genomic prediction (GP) is a cost-effective strategy for increasing selection intensity under genotype-by-environment interactions (G × E). This study developed a data-driven approach based on Environment–Phenotype Association (EPA) aimed at recycling important G × E information from historical breeding data. EPA was developed in two applications: (1) scanning a secondary source of genetic variation, weighted from the shared reaction-norms of past-evaluated genotypes and (2) pinpointing weights of the similarity among trial-sites (locations), given the historical impact of each envirotyping data variable for a given site. These results were then used as a dimensionality reduction …

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Discovery Of Novel Bioactive Tanshinones And Carnosol Analogues Against Breast Cancer, Miguel A. González-Cardenete, Natalia González-Zapata, Lucinda Boyd, Fatima Rivas Feb 2023

Discovery Of Novel Bioactive Tanshinones And Carnosol Analogues Against Breast Cancer, Miguel A. González-Cardenete, Natalia González-Zapata, Lucinda Boyd, Fatima Rivas

Faculty Publications

The abietane diterpenoids ferruginol (1), tanshinone IIA (3), and carnosol (4) are well-known for their interesting pharmacological properties, including antitumor, similar to other natural and semisynthetic abietanes. In this study, a pair of semisynthetic C18-functionalized analogues of 3 and 4 were prepared from the commercially available (+)-dehydroabietylamine or readily obtained methyl dehydroabietate. Semisynthetic ferruginol (1) and some selected analogues, together with the synthesized analogues, were tested in vitro for the inhibition of proliferation in four breast cancer cell lines, SUM149, MDA-MB231, T47D, and MCF07. As a result, several tested abietane analogues decreased cell proliferation and enhanced cell death, with IC50 …

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Inactivation Of The Ul37 Deamidase Enhances Virus Replication And Spread Of The Hsv-1(Vc2) Oncolytic Vaccine Strain And Secretion Of Gm-Csf, Carolyn M. Clark, Nithya Jambunathan, Therese M.A. Collantes, Konstantin G. Kousoulas Feb 2023

Inactivation Of The Ul37 Deamidase Enhances Virus Replication And Spread Of The Hsv-1(Vc2) Oncolytic Vaccine Strain And Secretion Of Gm-Csf, Carolyn M. Clark, Nithya Jambunathan, Therese M.A. Collantes, Konstantin G. Kousoulas

Faculty Publications

The HSV-1 (VC2) live-attenuated vaccine strain was engineered with specific deletions in the amino termini of glycoprotein K (gK) and membrane protein UL20, rendering the virus unable to enter neurons and establish latency. VC2 replicates efficiently in epithelial cell culture but produces lower viral titers and smaller viral plaques than its parental HSV-1 (F) wild-type virus. VC2 is an effective live-attenuated vaccine against HSV-1 and HSV-2 infections in mice and guinea pigs and an anti-tumor immunotherapeutic and oncolytic virus against melanoma and breast cancer in mouse models. Previously, we reported that the gK/UL20 complex interacts with the UL37 tegument protein, …

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A Simple Micromilled Microfluidic Impedance Cytometer With Vertical Parallel Electrodes For Cell Viability Analysis, Jason Eades, Julianne F. Audiffred, Micah Fincher, Jin Woo Choi, Steven A. Soper, William Todd Monroe Feb 2023

A Simple Micromilled Microfluidic Impedance Cytometer With Vertical Parallel Electrodes For Cell Viability Analysis, Jason Eades, Julianne F. Audiffred, Micah Fincher, Jin Woo Choi, Steven A. Soper, William Todd Monroe

Faculty Publications

Microfluidic impedance cytometry has been demonstrated as an effective platform for single cell analysis, taking advantage of microfabricated features and dielectric cell sensing methods. In this study, we present a simple microfluidic device to improve the sensitivity, accuracy, and throughput of single suspension cell viability analysis using vertical sidewall electrodes fabricated by a widely accessible negative manufacturing method. A microchannel milled through a 75 µm platinum wire, which was embedded into poly-methyl-methacrylate (PMMA), created a pair of parallel vertical sidewall platinum electrodes. Jurkat cells were interrogated in a custom low-conductivity buffer (1.2 ± 0.04 mS/cm) to reduce current leakage and …

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Editorial: Emerging Research Organisms In Regenerative Biology, Stefano Tiozzo, Igor Schneider Jan 2023

Editorial: Emerging Research Organisms In Regenerative Biology, Stefano Tiozzo, Igor Schneider

Faculty Publications

No abstract provided.

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Non-Equilibrium Colloidal Phenomena In Magnetic Fields And Photoillumination: From Controlling Living Microbots To Understanding Microplastics, Ahmed Al Harraq Jan 2023

Non-Equilibrium Colloidal Phenomena In Magnetic Fields And Photoillumination: From Controlling Living Microbots To Understanding Microplastics, Ahmed Al Harraq

LSU Doctoral Dissertations

Colloids are a ubiquitous class of materials composed of microscopic particles suspended in a continuous phase which are found in everyday products and in nature. Colloids are also useful models for studying the spontaneous arrangement of matter from individual building blocks to mesophases. Standard treatment of colloid science is based on the assumption of equilibrium conditions, as defined in traditional thermodynamics. However, novel assembly mechanisms and motility are unlocked by pushing colloids away from equilibrium using external energy. In addition, many colloids in nature and in industrial applications exchange energy and mass with the surrounding environment thus behaving in a …

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Investigating The Potential Role Of Termites As Pathogen Vectors In The Decline Of Ironwood Trees (Casuarina Equisetifolia) In Guam, Garima Setia Jan 2023

Investigating The Potential Role Of Termites As Pathogen Vectors In The Decline Of Ironwood Trees (Casuarina Equisetifolia) In Guam, Garima Setia

LSU Master's Theses

Termites have been found associated with the decline of Casuarina equisetifolia (ironwood), an important agro-forestry species in Guam. While the ironwood tree decline (IWTD) was first reported in 2002, its association with termites as well as with bacteria Ralstonia solanacearum and Klebsiella species (K. oxytoca and K. variicola) was determined in 2010 and 2012 respectively. In 2019, the termite species attacking the ironwood trees were identified as Nasutitermes takasagoensis, Coptotermes gestroi, and Microcerotermes crassus. However, the role of termites in IWTD is not known. Since termites are repositories of bacteria and consume wood, termite foragers might …

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Effect Od Different Sources And Application Rates Of Sulfur On Corn And Soybean Production Systems In Louisiana, Diego Mayorga Valladares Jan 2023

Effect Od Different Sources And Application Rates Of Sulfur On Corn And Soybean Production Systems In Louisiana, Diego Mayorga Valladares

LSU Master's Theses

Sulfur (S) is a structural component of amino acids such as cysteine and methionine and is involved in important functions within the plant like photosynthesis, carbon and nitrogen metabolism, protein synthesis of oils, and detoxification mechanisms. Sulfur deficiency in crops has intensified around the world. Some of the reasons are improvement in controlling SO2 emissions from industries, growing usage of high analysis S-free fertilizers and augmented cropping intensity. Sulfur fertilization has become an important factor in crop production systems and fertilization guidelines for S need to be up-to-date to improve use efficiency and compensate for rising prices of fertilizers. …

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The Impacts Of Immune Challenges On Fish Behavior And Physiology, Teisha King Jan 2023

The Impacts Of Immune Challenges On Fish Behavior And Physiology, Teisha King

LSU Doctoral Dissertations

For species living in dominance hierarchies, social rank dictates access to resources and often contributes to reproductive success. To ensure survival, individuals constantly evaluate trade- offs between crucial biological systems, like the reproductive and immune systems, depending on their social rank and physiological state. Little is known about how social species balance interactions between immune system function, fluctuations in social status and reproductive fitness, and the performance of behaviors necessary for maintaining social status when sick, particularly in fishes, the largest and most diverse group of vertebrates. My dissertation research uses a whole animal approach to examine how physiological profiles …

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Controls Of Physical Drivers On The Formation And Toxicity Of Harmful Cyanobacteria Blooms (Cyanohabs), Courtney N. Hammond Jan 2023

Controls Of Physical Drivers On The Formation And Toxicity Of Harmful Cyanobacteria Blooms (Cyanohabs), Courtney N. Hammond

LSU Master's Theses

Estuaries within the Gulf of Mexico are exhibiting profound alterations due to climatic changes and the implementation of coastal restoration activities. These changes are attributed to the increasing frequency of harmful cyanobacteria blooms (cyanoHABs) within Lake Pontchartrain, an estuary located in southeastern Louisiana, USA. There is a better understanding into how the opening of the Bonnet Carré Spillway (BCS) impacts cyanoHAB formations compared to the effect of other physical drivers when the spillway doesn’t dominate the system. The goal of this study is to provide a greater understanding of the baseline conditions when the BCS is closed and determine what …

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Development Of A Peptide-Based Protac Incorporating A Β-Hairpin Sequence, Hannah Catherine Hymel Jan 2023

Development Of A Peptide-Based Protac Incorporating A Β-Hairpin Sequence, Hannah Catherine Hymel

LSU Doctoral Dissertations

The ubiquitin-proteasome system (UPS) is a biochemical pathway primarily responsible for the degradation of damaged proteins. The UPS is regulated by E3 ubiquitin ligases, which recognize specific degradation sequences, or degrons, on a protein leading to protein ubiquitination and subsequent degradation by the proteasome. Proteolysis targeting chimeras (PROTACs) have emerged as a novel therapeutic agent to selectively degrade ‘undruggable’ targets; however, many peptide-based PROTACs suffer low cell permeability and high protease susceptibility. The goal of this work is to utilize degron-based substrates that function as cell penetrating peptides (CPPs) in a PROTAC to selectively degrade a target. The first part …

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Microplastics In Mainstem Mississippi River Fishes, Ahmed K. Gad, Kerrin Toner, Mark C. Benfield, Stephen R. Midway Jan 2023

Microplastics In Mainstem Mississippi River Fishes, Ahmed K. Gad, Kerrin Toner, Mark C. Benfield, Stephen R. Midway

Faculty Publications

Microplastics are ubiquitous in Earth’s ecosystems and many efforts have begun to understand their distributions. Large rivers, like the Mississippi River, provide a unique system in which to look at large-scale patterns of microplastic distribution. In this study, we sampled four species of widely-distributed fishes from five sites along the mainstem Mississippi River, from Minnesota to Louisiana, United States. Microplastics were found in all fish species and at all sites; however, microplastics increased in occurrence in the Lower Mississippi River. Fragments were the most common morphologies and polypropylene was the most common polymer detected. We also examined the hypothesis that …

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Editorial: Abiotic Stress: Molecular Genetics And Genomics, Volume Ii, Rohini Garg, Prasanta K. Subudhi, Rajeev K. Varshney, Mukesh Jain Jan 2023

Editorial: Abiotic Stress: Molecular Genetics And Genomics, Volume Ii, Rohini Garg, Prasanta K. Subudhi, Rajeev K. Varshney, Mukesh Jain

Faculty Publications

No abstract provided.

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Dual Targeting Of Mtor/Il-17a And Autophagy By Fisetin Alleviates Psoriasis-Like Skin Inflammation, Tithi Roy, Sergette Banang-Mbeumi, Samuel T. Boateng, Emmanuelle M. Ruiz, Roxane Cherille N. Chamcheu, Lin Kang, Judy A. King, Anthony L. Walker, Bolni Marius Nagalo, Konstantin G. Kousoulas, Stephane Esnault, Shile Huang, Jean Christopher Chamcheu Jan 2023

Dual Targeting Of Mtor/Il-17a And Autophagy By Fisetin Alleviates Psoriasis-Like Skin Inflammation, Tithi Roy, Sergette Banang-Mbeumi, Samuel T. Boateng, Emmanuelle M. Ruiz, Roxane Cherille N. Chamcheu, Lin Kang, Judy A. King, Anthony L. Walker, Bolni Marius Nagalo, Konstantin G. Kousoulas, Stephane Esnault, Shile Huang, Jean Christopher Chamcheu

Faculty Publications

Psoriasis is a chronic autoimmune inflammatory skin disorder characterized by epidermal hyperplasia and aberrant immune response. In addition to aberrant cytokine production, psoriasis is associated with activation of the Akt/mTOR pathway. mTOR/S6K1 regulates T-lymphocyte activation and migration, keratinocytes proliferation and is upregulated in psoriatic lesions. Several drugs that target Th1/Th17 cytokines or their receptors have been approved for treating psoriasis in humans with variable results necessitating improved therapies. Fisetin, a natural dietary polyphenol with anti-oxidant and anti-proliferative properties, covalently binds mTOR/S6K1. The effects of fisetin on psoriasis and its underlying mechanisms have not been clearly defined. Here, we evaluated the …

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Anaerobic Toluene Biodegradation Potential At A Superfund Site Where Toluene Biosynthesis Was Observed, George Carson Jan 2023

Anaerobic Toluene Biodegradation Potential At A Superfund Site Where Toluene Biosynthesis Was Observed, George Carson

LSU Master's Theses

At a Superfund site near Baton Rouge, LA, the subsurface injection of molasses has been used to stimulate anerobic reductive dechlorination of halogenated organic compounds (e.g., 1,2-dichloroethane and vinyl chloride) present in the groundwater. Following some molasses injections, temporary accumulation of toluene and p-cresol was observed in the groundwater. Accumulation of these aromatic hydrocarbons, which were not detected in the molasses, has been attributed to anaerobic biotransformation of the amino acids phenylalanine and tyrosine. Experiments reported here were conducted in support of an effort to determine if toluene biodegrading bacteria were present in the area where anaerobic toluene accumulation was …

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Explanation Needed: Understanding The Low Graduation Rates Of Spanish-Speaking English Learners In Southeastern Louisiana, Alice I. Garcia Jan 2023

Explanation Needed: Understanding The Low Graduation Rates Of Spanish-Speaking English Learners In Southeastern Louisiana, Alice I. Garcia

LSU Doctoral Dissertations

This qualitative research study used the case study method of one-on-one interviews to collect and examine the experiences of former English learners (ELs) who were unable to finish high school in southeastern Louisiana. This study aimed to identify specific factors that, using Everett Lee’s theory, pushed or pulled these ELs from school and affected their ability to graduate. The push factors that were identified included language, inadequate support, academic performance, discrimination, and lack of connection with school and culture. Pull factors that were identified included lack of prior education, immigration, poverty, pregnancy, being far from family, financially supporting family, and …

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Contagious Animality: Species, Disease, And Metaphor In Early Modern Literature And Culture, Jeremy Cornelius Jan 2023

Contagious Animality: Species, Disease, And Metaphor In Early Modern Literature And Culture, Jeremy Cornelius

LSU Doctoral Dissertations

In my dissertation, Contagious Animality: Species, Disease, and Metaphor in Early Modern Literature and Culture, I close read examples of Renaissance drama alongside their contemporary cultural texts to examine anxieties around social differences as constructed and mediated through what I call “contagious animality” in early modern English culture. Animal metaphors circulated anxieties around social differences on the early modern cultural stage in English drama where animality elicits uncertainties about identitarian constructions of difference. In this vein, I close read formal elements and their interactions with early modern culture to argue that animal metaphors transmit modes of speciating difference in …

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Characterization Of Antiviral Immunity, Host Virus Interactions, And Toxicity Of Agrochemical Residues In The Western Honey Bee, Christopher Fellows Jan 2023

Characterization Of Antiviral Immunity, Host Virus Interactions, And Toxicity Of Agrochemical Residues In The Western Honey Bee, Christopher Fellows

LSU Doctoral Dissertations

Honey bee colonies have perished at an alarming rate for over 15 years. Among the multitude of threats to bee health, virus infections and agrochemical exposure appear to be major drivers of colony loss. As virus infection is among the most damaging influences on bee health, we first investigated a putative target for antiviral immunity, termed KATP channels. We previously demonstrated that pharmacologically activating KATP channels induces the production of reactive oxygen species and increases survival during infection with Israeli Acute Paralysis Virus. Here, we demonstrate that KATP modulation and ROS induction reduce virus replication and enhance …

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Sexual Dimorphism In Corallite Size And Modularity Of A Broadcast Spawning Coral, Porites Lobata, Ricardo M. Pedraza-Pohlenz, Eduardo F. Balart, J. J.Adolfo Tortolero-Langarica, Alma Paola Rodríguez-Troncoso, Michael E. Hellberg, Orión Norzagaray-López, Rafael A. Cabral-Tena, Amílcar Leví Cupul-Magaña, David A. Paz-García Jan 2023

Sexual Dimorphism In Corallite Size And Modularity Of A Broadcast Spawning Coral, Porites Lobata, Ricardo M. Pedraza-Pohlenz, Eduardo F. Balart, J. J.Adolfo Tortolero-Langarica, Alma Paola Rodríguez-Troncoso, Michael E. Hellberg, Orión Norzagaray-López, Rafael A. Cabral-Tena, Amílcar Leví Cupul-Magaña, David A. Paz-García

Faculty Publications

Differences in selective pressures and the energetic cost of gametes in gonochoristic corals should vary with the sex of the colony, which may lead to sexual dimorphism. Coral colonies are composed of subunits (corallites) that create a complex morphological architecture. If corallite features are distinct between sexes, then the degree of coordinated change among these subunits may also vary (phenotypic modularity). This study tested for sexual dimorphism in the corallites of the reef-building coral Porites lobata, a gonochoric broadcast spawner, and compared this with previously demonstrated sexual dimorphism in its congener P. panamensis, a gonochoric brooder. Corallite area in P. …

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Flood Risk Assessment For Residences At The Neighborhood Scale By Owner/Occupant Type And First-Floor Height, Ayat Al Assi, Rubayet Bin Mostafiz, Carol J. Friedland, Md Adilur Rahim, Robert V. Rohli Jan 2023

Flood Risk Assessment For Residences At The Neighborhood Scale By Owner/Occupant Type And First-Floor Height, Ayat Al Assi, Rubayet Bin Mostafiz, Carol J. Friedland, Md Adilur Rahim, Robert V. Rohli

Faculty Publications

Evaluating flood risk is an essential component of understanding and increasing community resilience. A robust approach for quantifying flood risk in terms of average annual loss (AAL) in dollars across multiple homes is needed to provide valuable information for stakeholder decision-making. This research develops a computational framework to evaluate AAL at the neighborhood level by owner/occupant type (i.e., homeowner, landlord, and tenant) for increasing first-floor height (FFH). The AAL values were calculated here by numerically integrating loss-exceedance probability distributions to represent economic annual flood risk to the building, contents, and use. A simple case study for a census block in …

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Mouse Pancreatic Peptide Hormones Probed At The Sub-Single-Islet Level: The Effects Of Acute Corticosterone Treatment, Aleksandra Antevska, Connor C. Long, Samuel D. Dupuy, J. Jason Collier, Michael D. Karlstad, Thanh D. Do Jan 2023

Mouse Pancreatic Peptide Hormones Probed At The Sub-Single-Islet Level: The Effects Of Acute Corticosterone Treatment, Aleksandra Antevska, Connor C. Long, Samuel D. Dupuy, J. Jason Collier, Michael D. Karlstad, Thanh D. Do

Division of Basic Science Faculty Publications

We combine liquid chromatography coupled with ion mobility spectrometry-mass spectrometry to elucidate how short exposure to corticosterone (Cort) alters the output of mouse pancreatic islet hormones. The workflow enables the robust separation of mouse insulin 1 (Ins1) and insulin 2 (Ins2) and the detection of major islet hormones in a homogenate equivalent to 100-150 islet cells. We show that Ins2 has a unique structure and is degraded much faster than Ins1. Further investigation indicates that Ins2 may populate both T and R states, whereas Ins1 may not. The assemblies of Ins1’s B-chain also introduce more structural heterogeneity than Ins2. Collectively, …

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Skinks Of Oceania, New Guinea, And Eastern Wallacea: An Underexplored Biodiversity Hotspot, Alex Slavenko, Allen Allison, Christopher C. Austin, Aaron M. Bauer, Rafe M. Brown, Robert N. Fisher, Ivan Ineich, Bulisa Iova, Benjamin R. Karin, Fred Kraus, Sven Mecke, Shai Meiri, Clare Morrison, Paul M. Oliver, Mark O. Shea, Jonathan Q. Richmond, Glenn M. Shea, Oliver J.S. Tallowin, David G. Chapple Jan 2023

Skinks Of Oceania, New Guinea, And Eastern Wallacea: An Underexplored Biodiversity Hotspot, Alex Slavenko, Allen Allison, Christopher C. Austin, Aaron M. Bauer, Rafe M. Brown, Robert N. Fisher, Ivan Ineich, Bulisa Iova, Benjamin R. Karin, Fred Kraus, Sven Mecke, Shai Meiri, Clare Morrison, Paul M. Oliver, Mark O. Shea, Jonathan Q. Richmond, Glenn M. Shea, Oliver J.S. Tallowin, David G. Chapple

Faculty Publications

Context. Skinks comprise the dominant component of the terrestrial vertebrate fauna in Oceania, New Guinea, and Eastern Wallacea (ONGEW). However, knowledge of their diversity is incomplete, and their conservation needs are poorly understood. Aims. To explore the diversity and threat status of the skinks of ONGEW and identify knowledge gaps and conservation needs. Methods. We compiled a list of all skink species occurring in the region and their threat categories designated by the International Union for Conservation of Nature. We used available genetic sequences deposited in the National Center for Biotechnology Information's GenBank to generate a phylogeny of the region’s …

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Dissolved Organic Carbon Dynamics And Fluxes In Mississippi-Atchafalaya Deltaic System Impacted By An Extreme Flood Event And Hurricanes: A Multi-Satellite Approach Using Sentinel-2/3 And Landsat-8/9 Data, Bingqing Liu, Eurico J. D’Sa, Francesca Messina, Melissa M. Baustian, Kanchan Maiti, Victor H. Rivera-Monroy, Wei Huang, Ioannis Y. Georgiou Jan 2023

Dissolved Organic Carbon Dynamics And Fluxes In Mississippi-Atchafalaya Deltaic System Impacted By An Extreme Flood Event And Hurricanes: A Multi-Satellite Approach Using Sentinel-2/3 And Landsat-8/9 Data, Bingqing Liu, Eurico J. D’Sa, Francesca Messina, Melissa M. Baustian, Kanchan Maiti, Victor H. Rivera-Monroy, Wei Huang, Ioannis Y. Georgiou

Faculty Publications

Transport of riverine and wetland-derived dissolved organic carbon (DOC) spanning tidal wetlands, estuaries, and continental shelf waters functionally connects terrestrial and aquatic carbon reservoirs, yet the magnitude and ecological significance of this variable and its spatiotemporal linkage remains uncertain for coastal deltaic regions, such as Mississippi River Delta Plain, which includes Mississippi (MR) and Atchafalaya (AR) rivers and estuaries with vast expanses of wetlands and coastal forests. We examined DOC dynamics and fluxes in this large river-dominated wetland-estuarine system for the period between 2019 and 2021 that included an extreme river flood event in 2019, two major hurricanes (Barry in …

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Floodsafehome: Evaluating Financial Benefits And Savings Of Freeboard For Improved Decision-Making In Flood Risk Mitigation, Carol J. Friedland, Yong Cheol Lee, Rubayet Bin Mostafiz, Jiyoung Lee, Shifat P. Mithila, Robert V. Rohli, Md Adilur Rahim, Ehab Gnan, Monica Teets Farris Jan 2023

Floodsafehome: Evaluating Financial Benefits And Savings Of Freeboard For Improved Decision-Making In Flood Risk Mitigation, Carol J. Friedland, Yong Cheol Lee, Rubayet Bin Mostafiz, Jiyoung Lee, Shifat P. Mithila, Robert V. Rohli, Md Adilur Rahim, Ehab Gnan, Monica Teets Farris

Faculty Publications

Freeboard—elevation of a structure above the base flood elevation (BFE)—is a critical component in mitigating or avoiding flood losses. However, the unrevealed benefits and savings of freeboard installation have prevented communities from adopting this approach. To improve decision-making for residents, prospective residents, and other stakeholders in flood-vulnerable communities and enhance flood risk mitigation strategies, this study presents the methodology underlying a new webtool, FloodSafeHome, that estimates comprehensively the economic benefits and savings of freeboard installation for new construction of residential buildings. Specifically, the proposed evaluation framework has been designed to calculate monthly savings for individual buildings by assessing freeboard cost, …

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Visual Literacy Unframed: Planning An Oer To Improve College-Level Visual Analysis Skills, Marty Miller Jan 2023

Visual Literacy Unframed: Planning An Oer To Improve College-Level Visual Analysis Skills, Marty Miller

Faculty Publications

No abstract provided.

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A Community-Engaged Oral History Study As A Tool For Understanding Environmental Justice Aspects Of Human Exposures To Hazardous Waste Thermal Treatment Emissions In Colfax, La, Matilda Odera, Blair Kelley, Louie Rivers, Alyanna Wilson, Jessica Tran, Khushi Patel, Brenda Vallee, Wilma Subra, Jennifer A. Cramer, Jennifer K. Irving, Margaret Reams, Jennifer Richmond-Bryant Jan 2023

A Community-Engaged Oral History Study As A Tool For Understanding Environmental Justice Aspects Of Human Exposures To Hazardous Waste Thermal Treatment Emissions In Colfax, La, Matilda Odera, Blair Kelley, Louie Rivers, Alyanna Wilson, Jessica Tran, Khushi Patel, Brenda Vallee, Wilma Subra, Jennifer A. Cramer, Jennifer K. Irving, Margaret Reams, Jennifer Richmond-Bryant

Faculty Publications

This study investigates environmental justice (EJ) themes related to siting a hazardous waste thermal treatment facility near a low-income community of color. We investigated effects of living near a hazardous waste thermal treatment facility through three EJ aspects: recognitional, procedural, and distributive justice. The study involved the collection of oral history interviews from residents of Colfax, a town in Grant Parish, Louisiana, that hosts an open burn/open detonation hazardous waste thermal treatment facility. The facility processes materials such as munitions, theme park waste, and contaminated soils from Superfund sites, and it increased its volume drastically in 2014. Residents reported adverse …

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Exercise Training, Cardiac Biomarkers, And Cardiorespiratory Fitness In Type 2 Diabetes: The Hart-D Study, Kershaw V. Patel, Amit Saha, Colby R. Ayers, Anand Rohatgi, Jarett D. Berry, Jaime P. Almandoz, Neil M. Johannsen, Christopher Defilippi, Timothy S. Church, James A. De Lemos, Ambarish Pandey Jan 2023

Exercise Training, Cardiac Biomarkers, And Cardiorespiratory Fitness In Type 2 Diabetes: The Hart-D Study, Kershaw V. Patel, Amit Saha, Colby R. Ayers, Anand Rohatgi, Jarett D. Berry, Jaime P. Almandoz, Neil M. Johannsen, Christopher Defilippi, Timothy S. Church, James A. De Lemos, Ambarish Pandey

Clinical Research Faculty Publications

Background: High-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are cardiac biomarkers commonly detected in adults with type 2 diabetes (T2D) and are associated with heart failure risk. Objectives: The purpose of this study was to evaluate the effects of exercise training (ET) on hs-cTnT and NT-proBNP and evaluate the associations of these biomarkers with cardiorespiratory fitness among adults with T2D. Methods: Participants of the HART-D (Health Benefits of Aerobic and Resistance Training in Individuals with Type 2 Diabetes) trial who were randomly assigned to one of 3 ET groups or a non-exercise control group were included. …

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The Role Of Fmri In Drug Development: An Update, Owen Carmichael Jan 2023

The Role Of Fmri In Drug Development: An Update, Owen Carmichael

Clinical Research Faculty Publications

Functional magnetic resonance imaging (fMRI) of the brain is a technology that holds great potential for increasing the efficiency of drug development for the central nervous system (CNS). In preclinical studies and both early- and late-phase human trials, fMRI has the potential to improve cross-species translation of drug effects, help to de-risk compounds early in development, and contribute to the portfolio of evidence for a compound’s efficacy and mechanism of action. However, to date, the utilization of fMRI in the CNS drug development process has been limited. The purpose of this chapter is to explore this mismatch between potential and …

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