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Validation Of Remote Assessment Of Preschool Children's Anthropometrics And Motor Skills, Alyssa M. Button, E. Kipling Webster, Chelsea L. Kracht, Chelsea Hendrick, Anthony Okely, Kar Hau Chong, Penny Cross, Amanda E. Staiano Jan 2023

Validation Of Remote Assessment Of Preschool Children's Anthropometrics And Motor Skills, Alyssa M. Button, E. Kipling Webster, Chelsea L. Kracht, Chelsea Hendrick, Anthony Okely, Kar Hau Chong, Penny Cross, Amanda E. Staiano

Population and Public Health Science Faculty Publications

Introduction: Remotely delivered treatment and research procedures were rapidly adopted in response to the COVID-19 pandemic. However, it is unclear if these measures are valid. The purpose of this study was to compare the validity of anthropometry and motor skill proficiency measurements collected in a remote-setting to in-person setting among a sample of children ages 3–4 years. Methods: Child anthropometry and motor skill performance were measured in-person by trained assessors and by parents at home with remote supervision via videoconference by trained assessors. The following measures from the National Institutes of Health Toolbox were collected: anthropometry (height and weight), manual …

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Genotypic Variation Of Adaptive And Yield Component Traits Of Introduced Grain Oats (Avena Sativa L.) Grown In Bangladesh, Md Nashir Uddin, Md Ali Babar, Stephen A. Harrison, Ummea Khairun Fatema, S. M.Mostafa Kamal Khan Jan 2023

Genotypic Variation Of Adaptive And Yield Component Traits Of Introduced Grain Oats (Avena Sativa L.) Grown In Bangladesh, Md Nashir Uddin, Md Ali Babar, Stephen A. Harrison, Ummea Khairun Fatema, S. M.Mostafa Kamal Khan

Faculty Publications

Oat (Avena sativa L.) is considered a nutritious cereal. Its demand has surged across the globe steadily for half a decade, including in Bangladesh. Because there is no local variety, the current supply in Bangladesh solely relies on imports. This study aimed to introduce grain oats from the United States of America (U.S.A.) to Bangladesh and determine the extent of their adaptability and yield in this new environment. One hundred oat accessions were introduced in collaboration between North South University, Bangladesh and the University of Florida, U.S.A. They were evaluated in field conditions from November 2019 to April 2020 in …

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Leaky Gut And The Ingredients That Help Treat It: A Review, Ricardo Santos Aleman, Marvin Moncada, Kayanush J. Aryana Jan 2023

Leaky Gut And The Ingredients That Help Treat It: A Review, Ricardo Santos Aleman, Marvin Moncada, Kayanush J. Aryana

Faculty Publications

The human body is in daily contact with potentially toxic and infectious substances in the gastrointestinal tract (GIT). The GIT has the most significant load of antigens. The GIT can protect the intestinal integrity by allowing the passage of beneficial agents and blocking the path of harmful substances. Under normal conditions, a healthy intestinal barrier prevents toxic elements from entering the blood stream. However, factors such as stress, an unhealthy diet, excessive alcohol, antibiotics, and drug consumption can compromise the composition of the intestinal microbiota and the homeostasis of the intestinal barrier function of the intestine, leading to increased intestinal …

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On The Usefulness Of Mock Genomes To Define Heterotic Pools, Testers, And Hybrid Predictions In Orphan Crops, Ingrid Pinheiro Machado, Júlio César Dovale, Felipe Sabadin, Roberto Fritsche-Neto Jan 2023

On The Usefulness Of Mock Genomes To Define Heterotic Pools, Testers, And Hybrid Predictions In Orphan Crops, Ingrid Pinheiro Machado, Júlio César Dovale, Felipe Sabadin, Roberto Fritsche-Neto

Faculty Publications

The advances in genomics in recent years have increased the accuracy and efficiency of breeding programs for many crops. Nevertheless, the adoption of genomic enhancement for several other crops essential in developing countries is still limited, especially for those that do not have a reference genome. These crops are more often called orphans. This is the first report to show how the results provided by different platforms, including the use of a simulated genome, called the mock genome, can generate in population structure and genetic diversity studies, especially when the intention is to use this information to support the formation …

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Maternal Restricted- And Over- Feeding During Gestation Perturb Offspring Sperm Epigenome In Sheep, Linkai Zhu, Nicole Tillquist, Giovanna Scatolin, Rachael Gately, Mia Kawaida, Amanda Reiter, Sarah Reed, Steven Zinn, Kristen Govoni, Zongliang Jiang Jan 2023

Maternal Restricted- And Over- Feeding During Gestation Perturb Offspring Sperm Epigenome In Sheep, Linkai Zhu, Nicole Tillquist, Giovanna Scatolin, Rachael Gately, Mia Kawaida, Amanda Reiter, Sarah Reed, Steven Zinn, Kristen Govoni, Zongliang Jiang

Faculty Publications

In brief: Inadequate maternal nutrition during gestation can have immediate and lifelong effects on offspring. This study shows that maternal restricted - and over- nutrition during gestation do not affect semen characteristics in F1 male offspring but alters offspring sperm sncRNA profiles and DNA methylome in sheep. Abstract: There is a growing body of evidence that inadequate maternal nutrition during gestation can have immediate and lifelong effects on offspring. However, little is known about the effects of maternal nutrition during gestation on male offspring reproduction. Here, using a sheep model of maternal restricted - and over - nutrition (60 or …

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Sodium Propionate Or Sodium Butyrate Promotes Fatty Acid Oxidation In Hepg2 Cells Under Oxidative Stress, Kristina J. Cook, Ann Coulter, Michael Keenan, Frank Greenway, Jack N. Losso Jan 2023

Sodium Propionate Or Sodium Butyrate Promotes Fatty Acid Oxidation In Hepg2 Cells Under Oxidative Stress, Kristina J. Cook, Ann Coulter, Michael Keenan, Frank Greenway, Jack N. Losso

Faculty Publications

The beneficial effects of sodium butyrate (NaB) and sodium propionate (NaP) on fatty acid oxidation (FAO) genes and production of proinflammatory cytokines related to nonalcoholic fatty liver disease (NAFLD) were evaluated using HepG2 human liver hepatocellular carcinoma cells exposed to palmitate/oleate or lipopolysaccharides (LPSs) as a model. The results showed that NaP or NaB was able to promote FAO, regulate lipolysis, and reduce reactive oxygen species production by significantly increasing the mRNA expression of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α), peroxisome proliferator-activated receptor alpha (PPARα), adipose triglyceride lipase (ATGL), carnitine palmitoyltransferase 1 alpha (CPT1α), fibroblast growth factor 21 …

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Novel Liquor-Based Hot Sauce: Physicochemical Attributes, Volatile Compounds, Sensory Evaluation, Consumer Perception, Emotions, And Purchase Intent, Ricardo S. Aleman, Jhunior A. Marcía, Ismael Montero-Fernández, Joan King, Shirin Kazemzadeh Pournaki, Roberta Targino Hoskin, Marvin Moncada Jan 2023

Novel Liquor-Based Hot Sauce: Physicochemical Attributes, Volatile Compounds, Sensory Evaluation, Consumer Perception, Emotions, And Purchase Intent, Ricardo S. Aleman, Jhunior A. Marcía, Ismael Montero-Fernández, Joan King, Shirin Kazemzadeh Pournaki, Roberta Targino Hoskin, Marvin Moncada

Faculty Publications

Hot sauces are popular peppery condiments used to add flavor and sensory excitement to gastronomical preparations. While hot sauce occupies a retail category well over a century old, a novel production method using liquor as the base preservative rather than traditional vinegar is now commercially available, and its uniqueness begs study. Hot sauces produced with tequila, rum, vodka, and bourbon were compared to traditional vinegar-based hot sauces concerning physicochemical properties, volatile compounds, microbiological quality, sensory scores, emotions, and purchase intent (PI). Under accelerated conditions, pH, titratable acidity (TA), water activity (Aw), viscosity, and color were analyzed weekly for 20 weeks, …

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Serum Mannan-Binding Lectin-Associated Serine Proteases In Early Pregnancy For Gestational Diabetes In Chinese Pregnant Women, Ming Gao, Jing Li, Rui Zhang, Ninghua Li, Weiqin Li, Shuang Zhang, Peng Wang, Hui Wang, Zhongze Fang, Zhijie Yu, Gang Hu, Junhong Leng, Xilin Yang Jan 2023

Serum Mannan-Binding Lectin-Associated Serine Proteases In Early Pregnancy For Gestational Diabetes In Chinese Pregnant Women, Ming Gao, Jing Li, Rui Zhang, Ninghua Li, Weiqin Li, Shuang Zhang, Peng Wang, Hui Wang, Zhongze Fang, Zhijie Yu, Gang Hu, Junhong Leng, Xilin Yang

Population and Public Health Science Faculty Publications

Aims: This study aimed to explore associations of mannan-binding lectin-associated serine protease (MASP) levels in early pregnancy with gestational diabetes mellitus (GDM). We also examined interactions of MASPs and deoxycholic acid (DCA)/glycoursodeoxycholic acid (GUDCA) for the GDM risk and whether the interactive effects if any on the GDM risk were mediated via lysophosphatidylcholine (LPC) 18:0. Materials and methods: A 1:1 case-control study (n = 414) nested in a prospective cohort of pregnant women was conducted in Tianjin, China. Binary conditional logistic regressions were performed to examine associations of MASPs with the GDM risk. Additive interaction measures were used to examine …

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Effectiveness Of A Community-Based Structured Physical Activity Program For Adults With Type 2 Diabetes: A Randomized Clinical Trial, Aishee B. Mukherji, Di Lu, Feifei Qin, Haley Hedlin, Neil M. Johannsen, Sukyung Chung, Yukari Kobayashi, Francois Haddad, Cynthia Lamendola, Marina Basina, Ruth Talamoa, Jonathan Myers, Latha Palaniappan Dec 2022

Effectiveness Of A Community-Based Structured Physical Activity Program For Adults With Type 2 Diabetes: A Randomized Clinical Trial, Aishee B. Mukherji, Di Lu, Feifei Qin, Haley Hedlin, Neil M. Johannsen, Sukyung Chung, Yukari Kobayashi, Francois Haddad, Cynthia Lamendola, Marina Basina, Ruth Talamoa, Jonathan Myers, Latha Palaniappan

Clinical Research Faculty Publications

Importance: The efficacy of physical activity interventions among individuals with type 2 diabetes has been established; however, practical approaches to translate and extend these findings into community settings have not been well explored. Objective: To test the effectiveness of providing varying frequencies of weekly structured exercise sessions to improve diabetes control. Design, Setting, and Participants: The IMPACT (Initiate and Maintain Physical Activity in Communities Trial) study was a controlled randomized clinical trial (randomization occurred from October 2016 to April 2019) that included a 6-month, structured exercise intervention either once or thrice weekly vs usual care (UC; advice only). The exercise …

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Research Gaps And Opportunities In Precision Nutrition: An Nih Workshop Report, Bruce Y. Lee, José M. Ordovás, Elizabeth J. Parks, Cheryl A.M. Anderson, Albert László Barabási, Steven K. Clinton, Kayla De La Haye, Valerie B. Duffy, Paul W. Franks, Elizabeth M. Ginexi, Kristian J. Hammond, Erin C. Hanlon, Michael Hittle, Emily Ho, Abigail L. Horn, Richard S. Isaacson, Patricia L. Mabry, Susan Malone, Corby K. Martin, Josiemer Mattei, Simin Nikbin Meydani, Lorene M. Nelson, Marian L. Neuhouser, Brendan Parent, Nicolaas P. Pronk, Helen M. Roche, Suchi Saria, Frank A.J.L. Scheer, Eran Segal, Mary Ann Sevick, Tim D. Spector, Linda Van Horn, Krista A. Varady, Venkata Saroja Voruganti Dec 2022

Research Gaps And Opportunities In Precision Nutrition: An Nih Workshop Report, Bruce Y. Lee, José M. Ordovás, Elizabeth J. Parks, Cheryl A.M. Anderson, Albert László Barabási, Steven K. Clinton, Kayla De La Haye, Valerie B. Duffy, Paul W. Franks, Elizabeth M. Ginexi, Kristian J. Hammond, Erin C. Hanlon, Michael Hittle, Emily Ho, Abigail L. Horn, Richard S. Isaacson, Patricia L. Mabry, Susan Malone, Corby K. Martin, Josiemer Mattei, Simin Nikbin Meydani, Lorene M. Nelson, Marian L. Neuhouser, Brendan Parent, Nicolaas P. Pronk, Helen M. Roche, Suchi Saria, Frank A.J.L. Scheer, Eran Segal, Mary Ann Sevick, Tim D. Spector, Linda Van Horn, Krista A. Varady, Venkata Saroja Voruganti

Clinical Research Faculty Publications

Precision nutrition is an emerging concept that aims to develop nutrition recommendations tailored to different people's circumstances and biological characteristics. Responses to dietary change and the resulting health outcomes from consuming different diets may vary significantly between people based on interactions between their genetic backgrounds, physiology, microbiome, underlying health status, behaviors, social influences, and environmental exposures. On 11-12 January 2021, the National Institutes of Health convened a workshop entitled "Precision Nutrition: Research Gaps and Opportunities" to bring together experts to discuss the issues involved in better understanding and addressing precision nutrition. The workshop proceeded in 3 parts: part I covered …

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Total Energy Expenditure Is Repeatable In Adults But Not Associated With Short-Term Changes In Body Composition, Rebecca Rimbach, Yosuke Yamada, Hiroyuki Sagayama, Philip N. Ainslie, Lene F. Anderson, Liam J. Anderson, Lenore Arab, Issaad Baddou, Kweku Bedu-Addo, Ellen E. Blaak, Stephane Blanc, Alberto G. Bonomi, Carlijn V.C. Bouten, Pascal Bovet, Maciej S. Buchowski, Nancy F. Butte, Stefan G.J.A. Camps, Graeme L. Close, Jamie A. Cooper, Sai Krupa Das, Lara R. Dugas, Ulf Ekelund, Sonja Entringer, Terrence Forrester, Barry W. Fudge, Annelies H. Goris, Michael Gurven, Catherine Hambly, Asmaa El Hamdouchi, Marije B. Hoos, Sumei Hu, Noorjehan Joonas, Annemiek M. Joosen, Peter Katzmarzyk Dec 2022

Total Energy Expenditure Is Repeatable In Adults But Not Associated With Short-Term Changes In Body Composition, Rebecca Rimbach, Yosuke Yamada, Hiroyuki Sagayama, Philip N. Ainslie, Lene F. Anderson, Liam J. Anderson, Lenore Arab, Issaad Baddou, Kweku Bedu-Addo, Ellen E. Blaak, Stephane Blanc, Alberto G. Bonomi, Carlijn V.C. Bouten, Pascal Bovet, Maciej S. Buchowski, Nancy F. Butte, Stefan G.J.A. Camps, Graeme L. Close, Jamie A. Cooper, Sai Krupa Das, Lara R. Dugas, Ulf Ekelund, Sonja Entringer, Terrence Forrester, Barry W. Fudge, Annelies H. Goris, Michael Gurven, Catherine Hambly, Asmaa El Hamdouchi, Marije B. Hoos, Sumei Hu, Noorjehan Joonas, Annemiek M. Joosen, Peter Katzmarzyk

Clinical Research Faculty Publications

Low total energy expenditure (TEE, MJ/d) has been a hypothesized risk factor for weight gain, but repeatability of TEE, a critical variable in longitudinal studies of energy balance, is understudied. We examine repeated doubly labeled water (DLW) measurements of TEE in 348 adults and 47 children from the IAEA DLW Database (mean ± SD time interval: 1.9 ± 2.9 y) to assess repeatability of TEE, and to examine if TEE adjusted for age, sex, fat-free mass, and fat mass is associated with changes in weight or body composition. Here, we report that repeatability of TEE is high for adults, but …

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Direct And Indirect Effects Of Planting Density, Nitrogenous Fertilizer And Host Plant Resistance On Rice Herbivores And Their Natural Enemies, Finbarr G. Horgan, Eduardo Crisol-Martínez, Alexander M. Stuart, James M. Villegas, Ainara Peñalver-Cruz, Enrique A. Mundaca, Marivic O. Perez, Carmencita C. Bernal, Maria Liberty P. Almazan, Angelee F. Ramal Dec 2022

Direct And Indirect Effects Of Planting Density, Nitrogenous Fertilizer And Host Plant Resistance On Rice Herbivores And Their Natural Enemies, Finbarr G. Horgan, Eduardo Crisol-Martínez, Alexander M. Stuart, James M. Villegas, Ainara Peñalver-Cruz, Enrique A. Mundaca, Marivic O. Perez, Carmencita C. Bernal, Maria Liberty P. Almazan, Angelee F. Ramal

Faculty Publications

In rice ecosystems, seeding densities can be adjusted to compensate for lower nitrogen levels that reduce GHG emissions, or to increase farm profitability. However, density-induced changes to plant anatomy could affect herbivore-rice interactions, and alter arthropod community dynamics. We conducted an experiment that varied transplanting density (low or high), nitrogenous fertilizer (0, 60 or 150 kg added ha−1) and rice variety (resistant or susceptible to phloem-feeding insects) over two rice-growing seasons. Yields per plot increased with added nitrogen, but were not affected by variety or transplanting density. Planthopper and leafhopper densities were lower on resistant rice and in high-density field …

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Sk3 In Pomc Neurons Plays A Sexually Dimorphic Role In Energy And Glucose Homeostasis, Meng Yu, Jonathan C. Bean, Hailan Liu, Yang He, Yongjie Yang, Xing Cai, Kaifan Yu, Zhou Pei, Hesong Liu, Longlong Tu, Kristine M. Conde, Mengjie Wang, Yongxiang Li, Na Yin, Nan Zhang, Junying Han, Nikolas A. Scarcelli, Pingwen Xu, Yanlin He, Yong Xu, Chunmei Wang Dec 2022

Sk3 In Pomc Neurons Plays A Sexually Dimorphic Role In Energy And Glucose Homeostasis, Meng Yu, Jonathan C. Bean, Hailan Liu, Yang He, Yongjie Yang, Xing Cai, Kaifan Yu, Zhou Pei, Hesong Liu, Longlong Tu, Kristine M. Conde, Mengjie Wang, Yongxiang Li, Na Yin, Nan Zhang, Junying Han, Nikolas A. Scarcelli, Pingwen Xu, Yanlin He, Yong Xu, Chunmei Wang

Division of Basic Science Faculty Publications

Background: Pro-opiomelanocortin (POMC) neurons play a sexually dimorphic role in body weight and glucose balance. However, the mechanisms for the sex differences in POMC neuron functions are not fully understood. Results: We detected small conductance calcium-activated potassium (SK) current in POMC neurons. Secondary analysis of published single-cell RNA-Seq data showed that POMC neurons abundantly express SK3, one SK channel subunit. To test whether SK3 in POMC neurons regulates POMC neuron functions on energy and glucose homeostasis, we used a Cre-loxP strategy to delete SK3 specifically from mature POMC neurons. POMC-specific deletion of SK3 did not affect body weight in either …

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Interindividual Differences In Trainability And Moderators Of Cardiorespiratory Fitness, Waist Circumference, And Body Mass Responses: A Large-Scale Individual Participant Data Meta-Analysis, Jacob T. Bonafiglia, Paul A. Swinton, Robert Ross, Neil M. Johannsen, Corby K. Martin, Timothy S. Church, Cris A. Slentz, Leanna M. Ross, William E. Kraus, Jeremy J. Walsh, Glen P. Kenny, Gary S. Goldfield, Denis Prud’Homme, Ronald J. Sigal, Conrad P. Earnest, Brendon J. Gurd Dec 2022

Interindividual Differences In Trainability And Moderators Of Cardiorespiratory Fitness, Waist Circumference, And Body Mass Responses: A Large-Scale Individual Participant Data Meta-Analysis, Jacob T. Bonafiglia, Paul A. Swinton, Robert Ross, Neil M. Johannsen, Corby K. Martin, Timothy S. Church, Cris A. Slentz, Leanna M. Ross, William E. Kraus, Jeremy J. Walsh, Glen P. Kenny, Gary S. Goldfield, Denis Prud’Homme, Ronald J. Sigal, Conrad P. Earnest, Brendon J. Gurd

Clinical Research Faculty Publications

Although many studies have assumed variability reflects variance caused by exercise training, few studies have examined whether interindividual differences in trainability are present following exercise training. The present individual participant data (IPD) meta-analysis sought to: (1) investigate the presence of interindividual differences in trainability for cardiorespiratory fitness (CRF), waist circumference, and body mass; and (2) examine the influence of exercise training and potential moderators on the probability that an individual will experience clinically important differences. The IPD meta-analysis combined data from 1879 participants from eight previously published randomized controlled trials. We implemented a Bayesian framework to: (1) test the hypothesis …

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Association Between Weight Loss, Change In Physical Activity, And Change In Quality Of Life Following A Corporately Sponsored, Online Weight Loss Program, Christoph Höchsmann, James L. Dorling, Corby K. Martin, Conrad P. Earnest, Timothy S. Church Dec 2022

Association Between Weight Loss, Change In Physical Activity, And Change In Quality Of Life Following A Corporately Sponsored, Online Weight Loss Program, Christoph Höchsmann, James L. Dorling, Corby K. Martin, Conrad P. Earnest, Timothy S. Church

Clinical Research Faculty Publications

Background: The physiological benefits associated with corporately sponsored weight loss programs are increasingly well documented. However, less is known about how these programs affect employees’ quality of life (QoL). The purpose of the present analysis was to examine the association between weight loss, change in physical activity, and change in QoL following a corporately sponsored, online weight loss program. Methods: We examined the relationship between weight loss, self-reported change in physical activity, and change in several QoL indices in 26,658 participants (79% women) after the initial 10 weeks of the online weight loss program. The trend in changes in each …

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Study In Parkinson’S Disease Of Exercise Phase 3 (Sparx3): Study Protocol For A Randomized Controlled Trial, Charity G. Patterson, Elizabeth Joslin, Alexandra B. Gil, Wendy Spigle, Todd Nemet, Lana Chahine, Cory L. Christiansen, Ed Melanson, Wendy M. Kohrt, Martina Mancini, Deborah Josbeno, Katherine Balfany, Garett Griffith, Mac Kenzie Dunlap, Guillaume Lamotte, Erin Suttman, Danielle Larson, Chantale Branson, Kathleen E. Mckee, Li Goelz, Cynthia Poon, Barbara Tilley, Un Jung Kang, Malú Gámez Tansey, Nijee Luthra, Caroline M. Tanner, Jacob M. Haus, Giamila Fantuzzi, Nikolaus R. Mcfarland, Paulina Gonzalez-Latapi, Tatiana Foroud, Robert Motl, Michael A. Schwarzschild, Tanya Simuni Dec 2022

Study In Parkinson’S Disease Of Exercise Phase 3 (Sparx3): Study Protocol For A Randomized Controlled Trial, Charity G. Patterson, Elizabeth Joslin, Alexandra B. Gil, Wendy Spigle, Todd Nemet, Lana Chahine, Cory L. Christiansen, Ed Melanson, Wendy M. Kohrt, Martina Mancini, Deborah Josbeno, Katherine Balfany, Garett Griffith, Mac Kenzie Dunlap, Guillaume Lamotte, Erin Suttman, Danielle Larson, Chantale Branson, Kathleen E. Mckee, Li Goelz, Cynthia Poon, Barbara Tilley, Un Jung Kang, Malú Gámez Tansey, Nijee Luthra, Caroline M. Tanner, Jacob M. Haus, Giamila Fantuzzi, Nikolaus R. Mcfarland, Paulina Gonzalez-Latapi, Tatiana Foroud, Robert Motl, Michael A. Schwarzschild, Tanya Simuni

Clinical Research Faculty Publications

Background: To date, no medication has slowed the progression of Parkinson’s disease (PD). Preclinical, epidemiological, and experimental data on humans all support many benefits of endurance exercise among persons with PD. The key question is whether there is a definitive additional benefit of exercising at high intensity, in terms of slowing disease progression, beyond the well-documented benefit of endurance training on a treadmill for fitness, gait, and functional mobility. This study will determine the efficacy of high-intensity endurance exercise as first-line therapy for persons diagnosed with PD within 3 years, and untreated with symptomatic therapy at baseline. Methods: This is …

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Genetic Dissection Of Alkalinity Tolerance At The Seedling Stage In Rice (Oryza Sativa) Using A High-Resolution Linkage Map, Lovepreet Singh, Sapphire Coronejo, Rajat Pruthi, Sandeep Chapagain, Uttam Bhattarai, Prasanta K. Subudhi Dec 2022

Genetic Dissection Of Alkalinity Tolerance At The Seedling Stage In Rice (Oryza Sativa) Using A High-Resolution Linkage Map, Lovepreet Singh, Sapphire Coronejo, Rajat Pruthi, Sandeep Chapagain, Uttam Bhattarai, Prasanta K. Subudhi

Faculty Publications

Although both salinity and alkalinity result from accumulation of soluble salts in soil, high pH and ionic imbalance make alkaline stress more harmful to plants. This study aimed to provide molecular insights into the alkalinity tolerance using a recombinant inbred line (RIL) population developed from a cross between Cocodrie and Dular with contrasting response to alkalinity stress. Forty-six additive QTLs for nine morpho-physiological traits were mapped on to a linkage map of 4679 SNPs under alkalinity stress at the seedling stage and seven major-effect QTLs were for alkalinity tolerance scoring, Na+ and K+ concentrations and Na+:K+ ratio. The candidate genes …

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The 2018 World Cancer Research Fund (Wcrf)/American Institute For Cancer Research (Aicr) Score And Diabetes Risk In The Diabetes Prevention Program Outcomes Study (Dppos), Marissa M. Shams-White, Ashley H. Tjaden, Sharon L. Edelstein, Sarah Bassiouni, Lisa L. Kahle, Catherine Kim, Xavier Pi-Sunyer, Karla A. Temple, Elizabeth M. Venditti, Jill Reedy, Brandy M. Heckman-Stoddard, George A. Bray, Kishore M. Gadde, Iris W. Culbert, Jennifer Arceneaux, Annie Chatellier, Amber Dragg, Catherine M. Champagne, Crystal Duncan, Barbara Eberhardt, Frank Greenway, Fonda G. Guillory, April A. Herbert, Michael L. Jeffirs, Betty M. Kennedy, Erma Levy, Monica Lockett, Jennifer C. Lovejoy, Laura H. Morris, Lee E. Melancon, Donna H. Ryan, Deborah A. Sanford, Kenneth G. Smith, Lisa L. Smith Dec 2022

The 2018 World Cancer Research Fund (Wcrf)/American Institute For Cancer Research (Aicr) Score And Diabetes Risk In The Diabetes Prevention Program Outcomes Study (Dppos), Marissa M. Shams-White, Ashley H. Tjaden, Sharon L. Edelstein, Sarah Bassiouni, Lisa L. Kahle, Catherine Kim, Xavier Pi-Sunyer, Karla A. Temple, Elizabeth M. Venditti, Jill Reedy, Brandy M. Heckman-Stoddard, George A. Bray, Kishore M. Gadde, Iris W. Culbert, Jennifer Arceneaux, Annie Chatellier, Amber Dragg, Catherine M. Champagne, Crystal Duncan, Barbara Eberhardt, Frank Greenway, Fonda G. Guillory, April A. Herbert, Michael L. Jeffirs, Betty M. Kennedy, Erma Levy, Monica Lockett, Jennifer C. Lovejoy, Laura H. Morris, Lee E. Melancon, Donna H. Ryan, Deborah A. Sanford, Kenneth G. Smith, Lisa L. Smith

Population and Public Health Science Faculty Publications

Background: The 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) 3rd expert report highlights up-to-date Cancer Prevention Recommendations that may reduce burdens of many chronic diseases, including diabetes. This study examined if following a lifestyle that aligns with the recommendations – assessed via the 2018 WCRF/AICR Score – was associated with lower risk of type 2 diabetes in high-risk adults participating in the Diabetes Prevention Program Outcomes Study (DPPOS). Methods: The Diabetes Prevention Program (DPP) randomized adults at high risk for diabetes to receive a lifestyle intervention (ILS), metformin (MET) or a placebo (PLB) (mean: 3.2 years), with …

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Correlates Of The Physical Activity Decline During Childhood, Sara Pereira, Ana Carolina Reyes, Raquel Chaves, Carla Santos, Olga Vasconcelos, G. O. Tani, Peter T. Katzmarzyk, Adam Baxter-Jones, José Maia Dec 2022

Correlates Of The Physical Activity Decline During Childhood, Sara Pereira, Ana Carolina Reyes, Raquel Chaves, Carla Santos, Olga Vasconcelos, G. O. Tani, Peter T. Katzmarzyk, Adam Baxter-Jones, José Maia

Population and Public Health Science Faculty Publications

Purpose This study aimed to describe longitudinal trends in children's moderate-to-vigorous physical activity (MVPA) and to investigate associations with individual, familial, and school characteristics. Methods A sample of 341 Portuguese children age 5-10 yr (173 girls) from six age cohorts was followed over 3 yr using a mixed-longitudinal design. Physical activity, body mass index (BMI), gross motor coordination, and musculoskeletal fitness were assessed annually. Information on socioeconomic status and school characteristics was collected and analyzed with mixed models. Results MVPA shows a similar declining trend in both sexes, but on average, boys exceeded the World Health Organization recommendations of 60 …

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A Collaborative Approach To Adopting/Adapting Guidelines. The Australian 24-Hour Movement Guidelines For Children (5-12 Years) And Young People (13-17 Years): An Integration Of Physical Activity, Sedentary Behaviour, And Sleep, Anthony D. Okely, Davina Ghersi, Sarah P. Loughran, Dylan P. Cliff, Trevor Shilton, Rachel A. Jones, Rebecca M. Stanley, Julie Sherring, Natalie Toms, Simon Eckermann, Timothy S. Olds, Zhiguang Zhang, Anne Maree Parrish, Lisa Kervin, Sandra Downie, Jo Salmon, Clair Bannerman, Tamie Needham, Elaine Marshall, Jordy Kaufman, Layne Brown, Janecke Wille, Greg Wood, David R. Lubans, Stuart J.H. Biddle, Shane Pill, Anthea Hargreaves, Natalie Jonas, Natasha Schranz, Perry Campbell, Karen Ingram, Hayley Dean, Adam Verrender, Yvonne Ellis Dec 2022

A Collaborative Approach To Adopting/Adapting Guidelines. The Australian 24-Hour Movement Guidelines For Children (5-12 Years) And Young People (13-17 Years): An Integration Of Physical Activity, Sedentary Behaviour, And Sleep, Anthony D. Okely, Davina Ghersi, Sarah P. Loughran, Dylan P. Cliff, Trevor Shilton, Rachel A. Jones, Rebecca M. Stanley, Julie Sherring, Natalie Toms, Simon Eckermann, Timothy S. Olds, Zhiguang Zhang, Anne Maree Parrish, Lisa Kervin, Sandra Downie, Jo Salmon, Clair Bannerman, Tamie Needham, Elaine Marshall, Jordy Kaufman, Layne Brown, Janecke Wille, Greg Wood, David R. Lubans, Stuart J.H. Biddle, Shane Pill, Anthea Hargreaves, Natalie Jonas, Natasha Schranz, Perry Campbell, Karen Ingram, Hayley Dean, Adam Verrender, Yvonne Ellis

Population and Public Health Science Faculty Publications

Abstract: Background: In 2018, the Australian Government updated the Australian Physical Activity and Sedentary Behaviour Guidelines for Children and Young People. A requirement of this update was the incorporation of a 24-hour approach to movement, recognising the importance of adequate sleep. The purpose of this paper was to describe how the updated Australian 24-Hour Movement Guidelines for Children and Young People (5 to 17 years): an integration of physical activity, sedentary behaviour and sleep were developed and the outcomes from this process. Methods: The GRADE-ADOLOPMENT approach was used to develop the guidelines. A Leadership Group was formed, who identified existing …

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Low-Energy Dense Potato- And Bean-Based Diets Reduce Body Weight And Insulin Resistance: A Randomized, Feeding, Equivalence Trial, Candida J. Rebello, Robbie A. Beyl, Frank L. Greenway, Kelly C. Atteberry, Kristin K. Hoddy, John P. Kirwan Dec 2022

Low-Energy Dense Potato- And Bean-Based Diets Reduce Body Weight And Insulin Resistance: A Randomized, Feeding, Equivalence Trial, Candida J. Rebello, Robbie A. Beyl, Frank L. Greenway, Kelly C. Atteberry, Kristin K. Hoddy, John P. Kirwan

Division of Basic Science Faculty Publications

We evaluated the effect of diets low in energy density (1 kcal/g) and high in either potatoes (Potato) or pulses (Bean) on blood glucose control in participants with insulin resistance. We hypothesized that the Potato and Bean diets would have equivalent effects. This was an 8-week randomized, parallel design, controlled feeding study comparing Potato and Bean diets (50-55% carbohydrate, 30-35% fat, 15-20% protein). Equivalence was prespecified as the mean change in the blood glucose concentration for Potato that was within ±20% of the Bean diet. Thirty-six participants (age: 18-60 years, body mass index: 25-40 kg/m2) with insulin resistance (homeostatic model …

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Predicting Energy Intake In Adults Who Are Dieting And Exercising, Corey Gerving, Robert Lasater, James Starling, Danielle M. Ostendorf, Leanne M. Redman, Chad Estabrooks, Kevin Cummiskey, Vincent Antonetti, Diana M. Thomas Dec 2022

Predicting Energy Intake In Adults Who Are Dieting And Exercising, Corey Gerving, Robert Lasater, James Starling, Danielle M. Ostendorf, Leanne M. Redman, Chad Estabrooks, Kevin Cummiskey, Vincent Antonetti, Diana M. Thomas

Clinical Research Faculty Publications

Background: When a lifestyle intervention combines caloric restriction and increased physical activity energy expenditure (PAEE), there are two components of energy balance, energy intake (EI) and physical activity energy expenditure (PAEE), that are routinely misreported and expensive to measure. Energy balance models have successfully predicted EI if PAEE is known. Estimating EI from an energy balance model when PAEE is not known remains an open question. Objective: The objective was to evaluate the performance of an energy balance differential equation model to predict EI in an intervention that includes both calorie restriction and increases in PAEE. Design: The Antonetti energy …

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Effect Of Renin-Angiotensin System Antihypertensive Medication Use On Cognitive Function In Diabetes Mellitus With Obesity Or Overweight: An Ancillary Study To The Action For Health In Diabetes (Look Ahead) Trial, Whitney Wharton, Andrea Anderson, Kathleen M. Hayden, Owen T. Carmichael, Jeanne M. Clark, José A. Luchsinger, Mark Espeland, Sevil Yasar Dec 2022

Effect Of Renin-Angiotensin System Antihypertensive Medication Use On Cognitive Function In Diabetes Mellitus With Obesity Or Overweight: An Ancillary Study To The Action For Health In Diabetes (Look Ahead) Trial, Whitney Wharton, Andrea Anderson, Kathleen M. Hayden, Owen T. Carmichael, Jeanne M. Clark, José A. Luchsinger, Mark Espeland, Sevil Yasar

Clinical Research Faculty Publications

Aim: To determine whether antihypertensive medication (AHM) acting through the renin angiotensin system (RAS-AHM), compared with other AHM, can mitigate effects on cognitive function and risk for impairment in a population with type 2 diabetes mellitus (T2DM). Materials and Methods: This secondary analysis of the randomized controlled Action for Health in Diabetes (Look AHEAD) study included 712 community-dwelling participants who were followed over 15 years. Logistic regression was used to relate RAS-AHM use to cognitive impairment, and linear regression was used to relate RAS-AHM use to domain-specific cognitive function after adjusting for potential confounders. Results: A total of 563 individuals …

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Non-Destructive Quality Evaluation Of Tropical Fruit (Mango And Mangosteen) Purée Using Near-Infrared Spectroscopy Combined With Partial Least Squares Regression, Pimpen Pornchaloempong, Sneha Sharma, Thitima Phanomsophon, Kraisuwit Srisawat, Wasan Inta, Panmanas Sirisomboon, Witoon Prinyawiwatkul, Natrapee Nakawajana, Ravipat Lapcharoensuk, Sontisuk Teerachaichayut Dec 2022

Non-Destructive Quality Evaluation Of Tropical Fruit (Mango And Mangosteen) Purée Using Near-Infrared Spectroscopy Combined With Partial Least Squares Regression, Pimpen Pornchaloempong, Sneha Sharma, Thitima Phanomsophon, Kraisuwit Srisawat, Wasan Inta, Panmanas Sirisomboon, Witoon Prinyawiwatkul, Natrapee Nakawajana, Ravipat Lapcharoensuk, Sontisuk Teerachaichayut

Faculty Publications

Mango and mangosteen are commercially important tropical fruits with a short shelf life. Fruit processing is one of the alternatives to extend the shelf life of these fruits. Purée is one of the processed products of fresh fruit. In this research, the quality of mango and mangosteen purée was analyzed. Titratable acidity (TA) and total soluble solids (TSS) were predicted using non-destructive near-infrared (NIR) spectroscopy. A partial least squares regression (PLSR) model was developed based on the NIR spectra with a wavelength ranging from 800 to 2500 nm. The PLSR model returned a coefficient of determination (r2) and a ratio …

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Probiotic Incorporation Into Yogurt And Various Novel Yogurt-Based Products, Douglas W. Olson, Kayanush J. Aryana Dec 2022

Probiotic Incorporation Into Yogurt And Various Novel Yogurt-Based Products, Douglas W. Olson, Kayanush J. Aryana

Faculty Publications

Probiotics are commonly added to yogurt to provide many health benefits for the consumer. A description is provided for some commonly used probiotics in yogurt. A GRAS (generally recognized as safe) list of probiotic bacteria that can be added to yogurt or similar types of products is provided. Additionally, prebiotics, synbiotics (combination of prebiotics and probiotics), postbiotics, paraprobiotics, and psychobiotics can be added to yogurt. Probiotic yogurt can come in various forms in addition to spoonable yogurt, and yogurt can be used as an ingredient in other food products. Many useful functional ingredients can be applied to probiotic yogurt. The …

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Immobilization Of Lactobacillus Plantarum Ncimb 8826 Ameliorates Citrobacter Rodentium Induced Lesions And Enhances The Gut Inflammatory Response In C57bl/6 Weanling Mice, Emmanuel Kyereh, Diana Coulon, Ingeborg Langohr, Anne Raggio, Michael Keenan, Subramaniam Sathivel Dec 2022

Immobilization Of Lactobacillus Plantarum Ncimb 8826 Ameliorates Citrobacter Rodentium Induced Lesions And Enhances The Gut Inflammatory Response In C57bl/6 Weanling Mice, Emmanuel Kyereh, Diana Coulon, Ingeborg Langohr, Anne Raggio, Michael Keenan, Subramaniam Sathivel

Faculty Publications

Infectious diarrhea is a major cause of infant mortality in most developing countries. In this research, we evaluated the potential of immobilized Lactobacillus plantarum NCIMB 8826 on weanimix infant cereal and its effectiveness in reducing the severity of Citrobacter rodentium-induced diarrhea in weanling mice. Thirty-six C57BL/6 weanling mice were placed into four groups (n = 9 each; negative, positive, prevention and cure). Mice received either L. plantarum (109 CFU/g) immobilized on weanimix infant cereal 3 days before C. rodentium (109 CFU/ ml) infection (Prevention) or 3 days after C. rodentium infection (Cure). A positive control group was infected with C. …

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Interactions Of Cdkal1 Rs7747752 Polymorphism And Serum Levels Of L-Carnitine And Choline Are Related To Increased Risk Of Gestational Diabetes Mellitus, Hui Wang, Jing Li, Jinnan Liu, Junhong Leng, Weiqin Li, Zhijie Yu, Claudia H.T. Tam, Gang Hu, Ronald C.W. Ma, Zhongze Fang, Ying Wang, Xilin Yang Dec 2022

Interactions Of Cdkal1 Rs7747752 Polymorphism And Serum Levels Of L-Carnitine And Choline Are Related To Increased Risk Of Gestational Diabetes Mellitus, Hui Wang, Jing Li, Jinnan Liu, Junhong Leng, Weiqin Li, Zhijie Yu, Claudia H.T. Tam, Gang Hu, Ronald C.W. Ma, Zhongze Fang, Ying Wang, Xilin Yang

Population and Public Health Science Faculty Publications

Background: Interactions between genetic, metabolic, and environmental factors lead to gestational diabetes mellitus (GDM). We aimed to examine interactive effects of cyclin-dependent kinase 5 regulatory subunit-associated protein1-like 1(CDKAL1) rs7747752 polymorphism with low serum levels of L-carnitine, choline, and betaine for GDM. Methods: A nested case-control study of 207 GDM women and their one-to-one, age-matched controls was organized from a prospective cohort of pregnant women in Tianjin, China. Conditional logistic regressions were used to test associations between CDKAL1 rs7747752 and serum levels of L-carnitine, choline, and betaine, and the risk of GDM. Additive interactions were performed to examine interactive effects of …

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Effects Of A Lifestyle Intervention In Young Women With Gdm And Subsequent Diabetes, Gang Hu, Huikun Liu, Junhong Leng, Leishen Wang, Weiqin Li, Shuang Zhang, Wei Li, Gongshu Liu, Huiguang Tian, Shengping Yang, Zhijie Yu, Xilin Yang, Jaakko Tuomilehto Dec 2022

Effects Of A Lifestyle Intervention In Young Women With Gdm And Subsequent Diabetes, Gang Hu, Huikun Liu, Junhong Leng, Leishen Wang, Weiqin Li, Shuang Zhang, Wei Li, Gongshu Liu, Huiguang Tian, Shengping Yang, Zhijie Yu, Xilin Yang, Jaakko Tuomilehto

Population and Public Health Science Faculty Publications

The purpose of this study was to examine whether a 9-month intensive lifestyle intervention could lead to weight loss and improve cardiovascular risk factors among young women with both gestational diabetes mellitus (GDM) and newly diagnosed diabetes. A total of 83 young women, who had GDM and were subsequently diagnosed as type 2 diabetes at an average of 2.6 years after delivery, participated in a 9-month intensive lifestyle intervention and a follow-up survey at 6–9 years postintervention. After the 9-month intervention, these women had a weight loss of 2.90 kg (−4.02% of initial weight), decreased waist circumference (−3.12 cm), body …

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Evaluating The Viscoelastic Properties Of Alligator Skin Gelatin, Alligel, Compared To Mammalian And Fish Gelatins, Sarah E. Jimenez Dec 2022

Evaluating The Viscoelastic Properties Of Alligator Skin Gelatin, Alligel, Compared To Mammalian And Fish Gelatins, Sarah E. Jimenez

Honors Capstones

No abstract provided.

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Variation In Human Water Turnover Associated With Environmental And Lifestyle Factors, Yosuke Yamada, Xueying Zhang, Mary E.T. Henderson, Hiroyuki Sagayama, Herman Pontzer, Daiki Watanabe, Tsukasa Yoshida, Misaka Kimura, Philip N. Ainslie, Lene F. Andersen, Liam J. Anderson, Lenore Arab, Issad Baddou, Kweku Bedu-Addo, Ellen E. Blaak, Stephane Blanc, Alberto G. Bonomi, Carlijn V.C. Bouten, Pascal Bovet, Maciej S. Buchowski, Nancy F. Butte, Stefan G. Camps, Graeme L. Close, Jamie A. Cooper, Richard Cooper, Sai Krupa Das, Lara R. Dugas, Simon Eaton, Ulf Ekelund, Sonja Entringer, Terrence Forrester, Barry W. Fudge, Annelies H. Goris Nov 2022

Variation In Human Water Turnover Associated With Environmental And Lifestyle Factors, Yosuke Yamada, Xueying Zhang, Mary E.T. Henderson, Hiroyuki Sagayama, Herman Pontzer, Daiki Watanabe, Tsukasa Yoshida, Misaka Kimura, Philip N. Ainslie, Lene F. Andersen, Liam J. Anderson, Lenore Arab, Issad Baddou, Kweku Bedu-Addo, Ellen E. Blaak, Stephane Blanc, Alberto G. Bonomi, Carlijn V.C. Bouten, Pascal Bovet, Maciej S. Buchowski, Nancy F. Butte, Stefan G. Camps, Graeme L. Close, Jamie A. Cooper, Richard Cooper, Sai Krupa Das, Lara R. Dugas, Simon Eaton, Ulf Ekelund, Sonja Entringer, Terrence Forrester, Barry W. Fudge, Annelies H. Goris

Faculty Publications

Water is essential for survival, but one in three individuals worldwide (2.2 billion people) lacks access to safe drinking water. Water intake requirements largely reflect water turnover (WT), the water used by the body each day. We investigated the determinants of human WT in 5604 people from the ages of 8 days to 96 years from 23 countries using isotope-tracking (2H) methods. Age, body size, and composition were significantly associated with WT, as were physical activity, athletic status, pregnancy, socioeconomic status, and environmental characteristics (latitude, altitude, air temperature, and humidity). People who lived in countries with a low human development …

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