Digital Commons Network^™

Compbio And Miras-A Multi-Omic Analysis Platform Built On A Memory-Based Intelligence Engine, Ruteja A Barve, Chad E Storer, Wayne D Hoxsie, Curtis Marcum, Joshua F Mcmichael, Jared M Lalmansingh, Brittany K Smith, Mark R Johnson, Daniel J Kuster, Richard D Head

2020-Current year OA Pubs

As molecular and cellular technologies have advanced, the need to analyze and interpret the resulting vast and multi-modal data into actionable intelligence has become a rate-limiting factor in scientific advancement. While traditional knowledgebase-pathway tools and LLM-based AI tools provide a degree of support in data interpretation, both exhibit known limitations. Presented here is the CompBio multi-omic analysis platform built upon Memory-based Intelligent Reasoning System (MIRaS), an associative reasoning engine grounded in episodic and semantic memory, capable of inferring biological relationships directly from stored knowledge rather than from model training. The MIRaS system is not dependent on human-curated pathway knowledgebases, provides …

Quality Reveals What Quantity Conceals: Deceptive Equity Patterns In Urban Green Space Distribution, Zheng Xian, Yoshiharu Suzuki, Kun Liu, Clive E. Sabel, Naoki Nakaya, Atsushi Hozawa, Tomoki Nakaya

School of Geography, Earth and Environmental Sciences

Equitable provision of urban green space depends on how green space exposure is measured, yet aggregate, quantity-focused metrics can mask disparities in quality. We introduce the concept of deceptive equity, in which apparent distributional fairness conceals substantive inequality, and test it across 344 postcode areas in Sendai, Japan. Across three dimensions — ecological (NDVI), perceptual (Green View Index) and service provision (accessible park count) — we paired a quantity indicator with a quality indicator. A quantity–quality divergence emerged in every dimension: wherever a quality indicator showed a significant socioeconomic gradient it favoured affluent areas, whereas the corresponding quantity indicators were …

Usa-Kenyan Primary Care Teams Offer Phq-9 And Gad-7 Screening For Hiv+ Women In Kenya, Janet Meda, Laura L. Van Auker, Stephen J. Cavanagh, Miriam Carole Atieno Wagoro, Mariana Omenda

International Nursing Research Congress (INRC)

Background: As HIV treatment advances in sub-Saharan Africa, care for women living with HIV (WLWH) shifted from acute AIDS management to chronic disease care, with need to integrate mental health and HIV services. In low-resource settings comorbidities and antiretroviral (ARV) side effects can heighten anxiety and depression. Anemia, diabetes, hypertension, malaria, and ARV-related fatigue, pain, and neuropathy complicate diagnosis and treatment. Mental health screening in primary care improves identification and supports better outcomes. Rural and urban WLWH face different barriers and resources, emphasizing context-specific approaches. Expanding nursing education and advanced nursing roles may help reduce gaps in integrated care.

Objectives: …

The Dual Impact Of Professional And Community Interventions On Recidivism, Anjelika M. Dillard

Master of Arts in Human Services

This capstone project evaluates the effectiveness of professional and community interventions in reducing criminal recidivism and facilitating successful community reintegration for justice-involved individuals. Grounded in the Risk-Need-Responsivity (RNR) model, Desistance Theory, and Trauma-Informed Care frameworks, this study synthesizes contemporary behavioral health and criminological literature to examine how institutional programming and post-release community support interact to foster long-term behavioral change. The findings demonstrate that while evidence-based institutional treatments—such as Cognitive-Behavioral Therapy (CBT), Dialectical Behavior Therapy (DBT), and targeted vocational training—provide essential foundations for cognitive restructuring and skill acquisition, institutional programming alone is insufficient to prevent re-offending. Long-term desistance depends on an …

Mobile Health (Mhealth) Interventions To Promote Exclusive Breastfeeding In Low-Income Communities: A Scoping Review, Winarsih Winarsih, Dayat Subekti, Herdini Widyaningpertiwi, Tri Sunarsih, Endah Puji Astuti, Elvika Fit Ari Shanti

Journal of Health Research

Background: Exclusive breastfeeding (EBF) is a critical determinant of infant health and survival, yet its prevalence remains suboptimal in low-income communities globally. Barriers such as limited access to lactation support and misinformation continue to challenge EBF promotion efforts in these settings. This review maps and evaluates mHealth interventions that promote exclusive breastfeeding in low-income populations.

Methods: This scoping review was conducted following the JBI methodology and reported in accordance with the PRISMA-ScR guidelines. A systematic search of PubMed, Scopus, and Web of Science was conducted for articles published up to July 2025. Eligible studies involved any mHealth-based breastfeeding intervention …

Community Problems Need Community Solutions: Feminist Collaboration Across Campuses To Create Transformative Outcomes Through Community Engaged Learning, Elizabeth Wilhoit Larson, Jasmine R. Linabary, Ziyu Long, Kylie J. Johnson

Journal of Communication Pedagogy

This study presents a multi-institutional engaged pedagogy project responding to college food insecurity that involved partnerships among students, instructors, and campus food pantries from three U.S. universities. Through analysis of pre- and post-class surveys, class assignments, and instructor and community partner reflections, we argue that our feminist collaborative approach resulted in transformative outcomes in three areas: (a) heads, as the collaboration enabled critical understandings of food insecurity and how to combat it; (b) hearts, as the collaboration fostered a culture of care and (re)ignited shared passion in doing change work, and (c) hands, as the collaboration inspired actions to address …

Meeting Rhetorical And Relational Goals In Online Higher Education: Insights From A South African Case Study, Rentia Du Plessis, Diana Breshears, Luzelle Naudé Prof

Journal of Communication Pedagogy

This qualitative study examines the degree to which synchronous and asynchronous online learning platforms both supported and constrained the achievement of rhetorical and relational goals in a resource-constrained South African higher education context. As online teaching practices persist in the post-COVID era, understanding how to design pedagogically sound online environments is increasingly important, particularly in the Global South where cost, access, and connectivity pose significant constraints. Drawing on the Rhetorical and Relational Goals Theory (RRGT; Mottet et al., 2006) and Kaufmann et al.’s (2016) online learning climate dimensions, the study analyzes undergraduate students’ perceptions of Blackboard Collaborate, PowerPoint voice-overs, WhatsApp, …

Family Systems And Cultural Adaptation In Psychosocial Cancer Interventions For Latinx Families: A Critical Review, Nicole M. Vélez Agosto, Gladys Stephanie Hernandez, Sarah Chavez Chacon, Danielle Moreno, Cecilia Montiel-Nava

Psychological Science Faculty Publications

Cancer creates significant distress to Latinx family dynamics. Research on family interventions has omitted critical aspects that could significantly improve mental health outcomes in this vulnerable population, including the development of interventions with a robust theoretical framework that are simultaneously culturally aligned with deeply rooted Latinx values. This critical review addressed existing psychosocial interventions for families with a cancer patient, their strengths, and limitations. It expanded on three major themes relevant to designing cancer psychosocial interventions for Latinx, while also reviewing nine intervention studies that consider system-family components in intervention design and research, two of them with the additional integration …

Trauma Processing And Sleep Inconsistencies In Firefighters: A Proposed Program To Bridge Gaps And Set Heroes Up For Success, Megan Griffin

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

This doctoral paper presents a comprehensive review of the literature supporting the need for an integrated training program addressing sleep disruption, trauma exposure and processing, and substance use as a self-medication strategy among firefighter populations. Drawing on empirical research, the paper examines the prevalence and interaction of posttraumatic stress disorder (PTSD), moral injury, sleep disturbances, and substance use within this occupational group. The introduction provides operational definitions of PTSD and moral injury and synthesizes existing research on trauma exposure, sleep impairment, and substance use functions among firefighters. The literature review also highlights evidence-based, exposure informed interventions to facilitate adaptive trauma …

Promoting Developmentally Informed Justice: A Developmental Assessment Referral Framework For Juvenile Transfer Decisions, Carly F. Colman

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

The transfer of youth between juvenile courts and adult courts is one of the most consequential decisions made in the American legal system, as it will influence the youth’s legal outcomes, developmental trajectories, and long-term well-being. Advances in adolescent brain science show that there are many factors associated with youthful offending, including developmental immaturity, susceptibility to external influences, and ongoing neurobiological development—all of which are related to age, rather than being fixed criminal traits. Despite this growing body of evidence, legal decision-making in juvenile transfer and sentencing does not consistently incorporate individualized developmental data. This paper examines the important role …

A Brief Self-Help Intervention For Anxiety And Depressive Symptoms Utilizing Cognitive Behavioral Therapy And Dialectical Behavior Therapy Within Correctional Settings, Genevieve L. Ray

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Individuals within incarcerated settings are far more likely to experience symptoms that meet criteria for a mental health disorder compared to the general population. This population is often underserved due to various financial and resource constraints. Self-help interventions have grown in popularity due to their proven effectiveness and accessibility for consumers, particularly for anxiety and depression symptoms. A self-help intervention for those in a correctional setting would not require extensive additional personnel amid financial constraints and would increase access to care. Many self-help interventions that are currently published apply to the community population, but readily accessible resources that reside in …

A Policy Analysis Of Higher Education Support For Foster Youth In The Colorado Child Welfare System, Krystal Robles

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

This policy analysis examines how two Colorado laws, House Bill 22-1374 (Foster Care Success Act), and Senate Bill 22-008 (Higher Education Support for Foster Youth), aim to improve educational outcomes and long-term stability for youth who age out of the foster care system. Critical Policy Analysis (CPA) and Resilience Theory are used in this paper to examine how these policies address systemic inequities, promote resilience, and offer protective factors that support educational attainment. Using policy review, state policy comparison, stakeholder interviews, and community perspectives, I evaluated how the implementation, effectiveness, and limitations of these bills shape real-world impact. The findings …

Exploring Foundations Of Animal Host-Microbe Interactions In A Freshwater Sponge, Jacob S. Pawley

Electronic Theses and Dissertations

The most ancient eukaryotic immune defense mechanisms evolved in unicellular species. Multicellular eukaryotes, however, expanded these mechanisms to meet challenges unique to multicellular life, including barrier formation, long-distance cell signaling, and coordinated responses that eliminate microbial threats while minimizing damage to the host. As such, animal immune signaling pathways are exceptionally intricate and diverse. Though, most of what is understood about animal host–microbe interactions stems from a small handful of model systems. Here, I evaluate host–microbe interactions and innate immunity in sponges using the highly tractable freshwater sponge, Ephydatia muelleri. I report the discovery of an external host-derived matrix …

A Longitudinal Study Of Achilles Tendon Adaptation In Ncaa Division I Female Gymnasts: Associations With Menstrual Status, Birth Control Use, Pain, Limb Dominance, And Training Exposure, Mattie Jane Hyde

Electronic Theses and Dissertations

This longitudinal study evaluated Achilles tendon (AT) thickness in 22 NCAA Division I (DI) female gymnasts across three consecutive seasons in relation to menstruation, birth control use, pain, limb dominance, training week, and year of collegiate competition. Weekly ultrasound and athlete survey data were analyzed using mixed-effects models for absolute AT thickness and change in thickness from baseline measurements. Associations were primarily characterized by interactions rather than uniform effects of individual predictors. A Pain × Limb Dominance × Week × Year interaction was associated with both thickness outcomes across season-specific and combined analyses, with relationship directions varying by limb, season …

Glucagon Like Peptide 1 Receptor Agonists In Patients With Inflammatory Bowel Disease: Safety, Clinical Effectiveness And Anti-Inflammatory Mechanisms, Shannon Fernando, Joy Zhao, Kevan Josloff, Nida Zubair, Aakash Desai, Raina Shivashankar, Patricia L. Kozuch, Cuckoo Choudhary, Gary Lichtenstein, Priya Sehgal

Division of Gastroenterology and Hepatology Faculty Papers

INTRODUCTION: The prevalence of obesity among patients with inflammatory bowel disease (IBD) continues to rise and is associated with adverse IBD outcomes and diminished treatment response. This study reviews the clinical safety and efficacy of glucagon-like peptide-1 receptor agonists (GLP-1RA) in patients with IBD and comorbid obesity and explores their theorized anti-inflammatory mechanisms.

METHODS: Published articles through July 2026 were identified via a PubMed search for a narrative review using terms related to GLP-1RA, IBD, safety, effectiveness, and outcomes. Data extraction focused on GLP-1RA intervention details, IBD-related outcomes and inflammatory markers, and proposed anti-inflammatory mechanisms.

RESULTS: GLP-1RA therapy promotes weight …

Msw Portfolio: Tributaries Of Growth, Madison Hergenrader

Graduate Student Portfolios, Professional Papers, and Capstone Projects

Tributaries of Growth reflects mastery in the field of Social Work; reflections on the five elements and ten competencies as seen through the academic and practicum experiences at the University of Montana.

Becoming A Social Worker, Sheyanne Marie Herron

Graduate Student Portfolios, Professional Papers, and Capstone Projects

This portfolio is a reflective overview of my journey toward becoming a social worker. It highlights how my education, professional experiences, practicum placements, and coursework have shaped my development as a clinician, advocate, and leader. The portfolio demonstrates growth across the core MSW competencies, including ethical practice, assessment, intervention, research, policy, advocacy, cultural humility, and leadership. It also emphasizes my person-centered, strengths-based, and trauma-informed approach to practice and my commitment to social justice and lifelong learning.

Early Immune Dysregulation In Mtb/Siv Co-Infection Resists Cart Treatment At The Single-Cell Level, Riti Sharan, Yi Zou, Zhao Lai, Korri Weldon, Todd Bradley, Xi Luo, Hulin Wu, Shabaana A Khader, Deepak Kaushal

Faculty, Staff and Student Publications

Using single-cell transcriptomics of bronchoalveolar lavage cells from Mtb/SIV co-infected rhesus macaques on cART, we reveal profound immune dysregulation during early SIV co-infection of latent tuberculosis. SIV induces a sharp decline in CD4+ T cells, NK, and NKT cells, with incomplete recovery of Mtb-specific TH1 effector responses despite viral suppression. Instead, a persistent TH17-skewed environment emerges, alongside sustained myeloid inflammation driven by Type I interferon signaling and pro-inflammatory regulators such as KLF6 and NFKB1. Ligand-receptor network analyses demonstrate expanded CD4+ T cell-macrophage crosstalk and loss of immune homeostasis that cART fails to fully restore. These findings expose …

Determinants Of Antenatal Care Utilization: A Community-Based, Cross-Sectional Study In Morang And Sunsari Districts, Eastern Nepal, Sunil Shah, Chandra Jha

Journal of Social, Behavioral, and Health Sciences

This study examined the factors influencing antenatal care (ANC) utilization in the eastern region of Nepal, focusing on the Morang and Sunsari districts, with the aim of identifying key determinants affecting ANC uptake and assessing the extent of ANC service utilization among mothers. Using lot quality assurance sampling, a community-based, descriptive, cross-sectional design was employed, surveying 164 mothers who had given birth within the previous 12 months; data were collected from June through November 2023. Data were collected through a semi-structured questionnaire and analyzed using SPSS, with descriptive statistics, chi-square tests, and logistic regression. Findings revealed that 80.5% of respondents …

Understanding The Lived Experiences Of Autistic Students As They Navigate Nutrition In Higher Education: A Hermeneutic Study, Amanda Beeman

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study is to interpret how adult students with ASD in higher education navigate nutritional choices. This study was guided by Bronfenbrenner’s ecological systems theory, which explains the relationship between environmental factors and individual health and well-being. A hermeneutic phenomenological approach was used to examine how students with ASD experienced nutrition within the higher education environment. The central research question asked how adult higher education students with ASD experienced and navigated nutrition in the context of college life. The sample included 10 adult participants with ASD enrolled in a higher education institution. Data were collected …

Spn 313: Advanced Communication Skills, Aleksin Ortega, Aleksín H. Ortega

Open Educational Resources

This syllabus for SPN 313 (Advanced Communication Skills) at the College of Staten Island, CUNY, presents a zero-textbook-cost, OER-based course in advanced academic writing in Spanish designed for a mixed population of heritage speakers and advanced second-language learners. The course follows a genre-based progression through four textual forms — description, narration, exposition, and argumentation — organized around a recursive writing process of drafting, instructor feedback, and revision. Its signature assignment, the Autobiografía lingüística (Linguistic Autobiography), serves as the Spanish program's ACTFL-aligned assessment artifact and is supported by a structured independent-inquiry project on dialectal variation. The syllabus foregrounds the dialectal diversity …

The Experience Of Sleep And Academic Performance Among African American College Students: A Case Study, Jamean Alma Alexander

Walden Dissertations and Doctoral Studies

The transition to college presents significant challenges for African American college students, particularly in developing effective study habits and maintaining healthy sleep behaviors that support academic success. Despite growing evidence linking sleep and academic performance, limited research has explored how African American students attending historically Black colleges and universities (HBCUs) perceive these experiences. The purpose of this qualitative case study was to explore the perceptions and experiences of African American college students regarding sleep habits, study habits, and academic performance. Guided by three research questions, data were collected through semi structured interviews with 12 African American students attending HBCUs in …

Post-Pandemic Telebehavioral Health: Sustaining And Regulating Remote Mental Health Care As A Core Modality, Weiqiao Dong

Dartmouth College Master’s Theses

The United States continues to face a persistent mental health crisis after the COVID-19 pandemic, raising a policy question about the long-term role and regulation of telebehavioral health as a core modality of care. This thesis examines that question through a case study of New York State, an early center of the pandemic and a leader in telehealth policy reform.

Guided by the Health Policy Triangle framework, this thesis integrates longitudinal data from all 62 New York counties for 2010-2025 with a 2025 cross-sectional dataset covering 61 counties. Seventeen standardized indicators are organized into four dimensions: geographic, economic, demographic, and …

Clinical Practice Guideline For Sepsis In Skilled Nursing Facility, Chinyere Okoroh

Walden Dissertations and Doctoral Studies

Sepsis is a life-threatening condition that can rapidly lead to organ dysfunction, septic shock, and death if not recognized and treated early. Older adults in skilled nursing facilities (SNFs) are especially vulnerable because of age-related physiological changes, chronic conditions, weakened immunity, and increased exposure to infections. Consequently, sepsis remains a major cause of hospital readmissions, mortality, and healthcare utilization among SNF residents. The SNF serving as the site for this Doctor of Nursing Practice (DNP) project experienced increased hospital readmissions associated with recurrent sepsis, highlighting the need for a standardized, evidence-based approach to sepsis recognition and management. The practice-focused question …

Comparative Analysis Of Metabolic Vulnerability In The Standard American And Carnivore Diets Using The Mvx Plus Biomarker Panel, Susan E. Fitzgerald

Doctoral Dissertations and Projects

Poor diet is a leading cause of mortality, contributing to an estimated one million deaths in the United States and eleven million deaths annually worldwide, with diet-related chronic disease accounting for approximately 85% of U.S. healthcare spending. The Standard American Diet (SAD) is widely recognized as causing systemic inflammation, while the carnivore diet is under-researched with unknown long-term effects. The purpose of this cross-sectional secondary analysis was to examine the impact of these two dietary patterns on metabolic vulnerability using the Metabolic Vulnerability Index Plus (MVX Plus), a multidimensional biomarker panel that quantifies systemic inflammation, metabolic malnutrition, and metabolic resilience …

“It’S Not Just A Story”: A Phenomenological Study Of Evangelical Christian Women Who Have Disclosed Childhood Sexual Abuse To An Evangelical Pastor, Erin M. Collins

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to describe Evangelical Christian women's experiences disclosing childhood sexual abuse to their pastor in the southeastern region of the United States. Childhood sexual abuse has been a globally studied public health and human rights concern. Over the past few decades, the knowledge of childhood sexual abuse has accumulated in a substantial amount of empirical research, through state and federal legislations, as well as with media coverage. This research has shed light on the gaps in the study regarding disclosure of childhood sexual abuse to an evangelical pastor. Most available research discussed the physiological …

The Knowledge, Skills, And Abilities Of Certified Anduncertified Medical Assistants In Medical Clinics: A Hermeneutical Phenomenology Study, Shannon Waller

Doctoral Dissertations and Projects

The purpose of this qualitative hermeneutical phenomenological study was to explore how supervising clinicians, including medical doctors, physician assistants, and nurse practitioners, described the knowledge, skills, and abilities of certified and uncertified medical assistants in healthcare clinics in the United States. The problem was that it was unknown how supervising clinicians described the knowledge, skills, and abilities of certified and uncertified medical assistants. Becker’s human capital theory served as the theoretical framework for this study. Participants were recruited through professional social media platforms and clinician-specific online communities. Data collection included semi-structured interviews, a focus group, andwritten responses to a writing …

The Posture Of Recovery; A Quantitative Analysis Of Post-Exercise Heart Rate Restorateion In College Athletes, Matthew Scott Ferriter

Doctoral Dissertations and Projects

Heart rate recovery (HRR) has been frequently used as a noninvasive indicator of autonomic reactivity following high-intensity exercise. However, limited research has explored the effects of post-exercise body posture (PEBP) on HRR following acute bouts of high-intensity exercise in collegiate athletes. The purpose of this quantitative repeated-measures experimental study was to investigate if recovery posture (supine [SUP]; tripod [TRI]; standing upright [SU]) affected HRR during the first five minutes following a standardized high-intensity interval training (HIIT) session. Thirty-seven collegiate athletes completed three total testing sessions. Participants completed all three recovery posture conditions in a randomized order. Heart rate (HR) was …

Grace, Reciprocity Norms, Adverse Life Events, Religious Struggle, Salience Of Religion, Relationship To God As Modifiers, Calvin Jay Slot

Doctoral Dissertations and Projects

The purpose of this quantitative study was to determine whether adverse life events, reciprocity norms, relationship to God, salience of religion, religious struggle and/or grace moderate the frequency of church attendance-physical health relationship or if the psychospiritual variables interact with adverse life events (ALE). 1,000 participants were recruited through Prolific to produce a sample representative of the United States population. An additional 20 participants were recruited through pastors of three churches in Illinois. Multiple linear regression revealed relationship to God, religious struggle, reciprocity norms, and ALE were moderators. Additionally, religious struggle and negative reciprocity norms interacted with adverse life events, …

Navigating The Maternal Health Crisis: Enhancing Maternal Health Outcomes In New Jersey, Nyrobi Barnes

Doctoral Dissertations and Projects

The purpose of the study was to better understand the implications of race and ethnicity on perinatal health experiences and maternal health outcomes in non-Hispanic Black women (nHBw) in New Jersey and mitigate the maternal health crisis. A secondary outcome was to propose an evidence-based initiative to elicit equitable care in New Jersey via grant-funded programs at the New Jersey Department of Health. Although New Jersey has made progress in improving maternal and infant health outcomes, racial disparities continue to persist. The research aims to further understand implications of race and ethnicity on adverse perinatal health experiences and maternal health …