Digital Commons Network^™

Pharmacological Inhibition Of Lipolysis Prevents Adverse Metabolic Outcomes During Glucocorticoid Administration, Melissa A. Linden, Susan J. Burke, Humza A. Pirzadah, Tai Yu Huang, Heidi M. Batdorf, Walid K. Mohammed, Katarina A. Jones, Sujoy Ghosh, Shawn R. Campagna, J. Jason Collier, Robert C. Noland

Division of Basic Science Faculty Publications

Objective: Glucocorticoids are one of the most commonly prescribed classes of anti-inflammatory drugs; however, chronic treatment promotes iatrogenic (drug-induced) diabetes. As part of their physiological role, glucocorticoids stimulate lipolysis to spare glucose. We hypothesized that persistent stimulation of lipolysis during glucocorticoid therapy plays a causative role in the development of iatrogenic diabetes. Methods: Male C57BL/6J mice were given 100 μg/mL corticosterone (Cort) in the drinking water for two weeks and were fed either normal chow (TekLad 8640) or the same diet supplemented with an adipose triglyceride lipase inhibitor (Atglistatin - 2 g/kg diet) to inhibit the first step of lipolysis. …

Quality Of Farmed Shrimp (Penaeus Monodon, Fabricius, 1798 And Macrobrachium Rosenbergii, Deman, 1879) As Affected By Melanosis Inhibiting Compounds, M. Khan, J. A. Lively

Faculty Publications

A problem associated with shrimp is blackspot or melanosis and to prevent blackspot, sulfites have been used for years but come with additional health risks. Newer 4-hexylresorcinol formulations exist that allow sulfite-free shrimp, but effects on the quality of Penaeus monodon Fabricius, 1798, and Macrobrachium rosenbergii, de Man, 1879, beyond melanosis prevention are unknown. Adverse effects on the quality of the shrimp from melanosis prevention treatments would negatively offset the benefits of a sulfite-free product. In order to determine if prevention compounds (sulfite powder or 4-hexylresorcinol based compounds, Everfresh® and Xyrex® Prawnfresh™) affect quality, proximate composition and total plate count …

Dna Methylation Near Cpt1a And Changes In Triglyceride-Rich Lipoproteins In Response To Weight-Loss Diet Interventions, Xiang Li, Xiaojian Shao, Qiaochu Xue, Minghao Kou, Catherine M. Champagne, Boryana S. Koseva, Yoriko Heianza, Elin Grundberg, Lydia A. Bazzano, George A. Bray, Frank M. Sacks, Lu Qi

Population and Public Health Science Faculty Publications

Context: Carnitine palmitoyltransferase-1A, encoded by the CPT1A gene, plays a key role in the oxidation of long-chain fatty acids in the mitochondria and may be important in triglyceride metabolism. Previous work has shown that high fat intake was negatively associated with CPT1A methylation and positively associated with CPT1A expression. Objective: We aim to investigate the association of DNA methylation (DNAm) at the CPT1A gene with reductions in triglycerides and triglyceride-rich lipoproteins (TRLs) in response to weight-loss diet interventions. Methods: The current study included 538 White participants, who were randomly assigned to 1 of 4 diets varying in macronutrient components. We …

Trends In Gestational Weight Gain In Louisiana, March 2019 To March 2022, Emily W. Harville, Chelsea L. Kracht, Nicole L. Cohen, Elizabeth F. Sutton, Maryam Kebbe, Leanne M. Redman

Clinical Research Faculty Publications

IMPORTANCE Average gestational weight gain (GWG) increased during the COVID-19 pandemic, but it is not known whether this trend has continued. OBJECTIVE To examine patterns of GWG during the COVID-19 pandemic by delivery and conception timing through the second year of the pandemic. DESIGN, SETTING, AND PARTICIPANTS This cohort study is a retrospective review of birth certificate and delivery records from 2019 to 2022. Electronic health records were from the largest delivery hospital in Louisiana. Participants included all individuals giving birth from March 2019 to March 2022. Data analysis was performed from October 2022 to July 2023. EXPOSURE Delivery date …

Chemical Characterization And Impact Of Nipple Fruit (Solanum Mammosum) On The Characteristics Of Lactobacillus Acidophilus La K, Ricardo S. Aleman, Dany Avila, Allan Avila, Jack N. Losso, David Picha, Zhimin Xu, Kayanush Aryana

Faculty Publications

Nipple fruit (Solanum mammosum) has been considered to have great pharmaceutical potential because of its high amounts of solamargine and solasonine. This study aimed to examine the effect of nipple fruit at different concentrations (0.5%, 1%, and 2% (w/v)) on the viability, acid, bile, lysozyme, and gastric juice tolerance, and protease activity of Lactobacillus acidophilus LA K. The viability was studied in MRS broth. Acid tolerance was determined by adjusting the pH to 2, whereas bile tolerance was examined with oxgall 0.3% (w/v) in MRS broth. Lysozyme resistance was investigated in an electrolyte solution with lysozyme (100 mg/L), while gastric …

No Strong Evidence Of The Protein Leverage Hypothesis In Pregnant Women With Obesity And Their Infants, Maryam Kebbe, Jasper Most, Abby D. Altazan, Leanne M. Redman

Clinical Research Faculty Publications

Objective: The goal of this study was to investigate the role of dietary protein on macronutrient and energy intake, maternal adiposity during pregnancy, and infant adiposity at birth. Methods: In 41 women with obesity, early-pregnancy (13–16 weeks) protein intake was assessed with food photography and expressed as a ratio of Estimated Average Requirements (EAR) in pregnancy for protein (0.88 g/kg/d), herein “protein balance.” Energy intake was measured by the intake-balance method, gestational weight gain as grams per week, and fat mass by a three-compartment model. Spearman correlations and linear models were computed using R version 4.1.1 (p < 0.05 considered significant). Results: Women had a mean (SD) age of 27.5 (4.8) years and a pregravid BMI of 34.4 (2.9), kg/m2, and the majority were non-White (n = 23, 56.1%). Protein balance in early pregnancy was not significantly associated with energy intake across mid and mid/late pregnancy (β = 328.7, p = 0.30 and β = 286.2, p = 0.26, respectively) or gestational weight gain (β = 117.0, p = 0.41). Protein balance was inversely associated with fat mass in early, mid, and late pregnancy (β = −10.6, p = 0.01, β = −10.4, p = 0.03, β = −10.3, p = 0.03, respectively). Protein balance did not predict infant adiposity at birth (p > 0.05). Conclusions: Low …

Anoctamin 4 Channel Currents Activate Glucose-Inhibited Neurons In The Mouse Ventromedial Hypothalamus During Hypoglycemia, Longlong Tu, Jonathan C. Bean, Yang He, Hailan Liu, Meng Yu, Hesong Liu, Nan Zhang, Na Yin, Junying Han, Nikolas A. Scarcelli, Kristine M. Conde, Mengjie Wang, Yongxiang Li, Bing Feng, Peiyu Gao, Zhao Lin Cai, Makoto Fukuda, Mingshan Xue, Qingchun Tong, Yongjie Yang, Lan Liao, Jianming Xu, Chunmei Wang, Yanlin He, Yong Xu

Division of Basic Science Faculty Publications

Glucose is the basic fuel essential for maintenance of viability and functionality of all cells. However, some neurons —namely, glucose-inhibited (GI) neurons — paradoxically increase their firing activity in low-glucose conditions and decrease that activity in high-glucose conditions. The ionic mechanisms mediating electric responses of GI neurons to glucose fluctuations remain unclear. Here, we showed that currents mediated by the anoctamin 4 (Ano4) channel are only detected in GI neurons in the ventromedial hypothalamic nucleus (VMH) and are functionally required for their activation in response to low glucose. Genetic disruption of the Ano4 gene in VMH neurons reduced blood glucose …

Evaluating Vaccine Management Strategies For Edwardsiella Ictaluri Infections In Zebrafish (Danio Rerio), Brandy Malbrough

LSU Master's Theses

Aquaculture is a globally important industry that faces significant challenges due to infectious diseases, which can result in substantial financial losses. In 2011, a new strain of Edwardsiella ictaluri emerged as a major pathogen affecting zebrafish in the ornamental fish industry, leading to high mortality rates and posing a severe threat to the sector. Vaccines provide potential benefits for disease prevention in aquaculture, particularly live-attenuated vaccines (LAVs), which induce strong host immune responses. Bacterial attenuation for vaccine development has evolved from serial passage to more targeted genetic modification techniques. However, regulatory constraints limit the availability of licensed LAVs for aquaculture. …

Nutrient Content And Bioactive Compounds In Ornamental Type Sweetpotatoes, Sandeep Kaur Sran

LSU Master's Theses

Abstract

The leaf and root composition of different cultivars of ornamental sweetpotatoes (‘Blackie’, ‘Kakura’, ‘Manihi’, ‘Makatea’, ‘Tahiti’ and ‘Tatakoto’) were analyzed, and the impact of various factors on the levels of nutrients, vitamins, antioxidants, phenolic compounds, sugars, and organic acids in these sweetpotato cultivars were determined. The principal macronutrients found in sweetpotato foliage and roots were nitrogen (N), potassium (K), phosphorus (P), magnesium (Mg), calcium (Ca), and sulfur (S). Nitrogen was the most abundant macronutrient among all cultivars in sweetpotato foliage, whereas potassium was the most abundant macronutrient in sweetpotato roots. The principal micronutrients found in foliage and roots were …

Morphological And Molecular Characterization Of The Olfactory System In The Formosan Subterranean Termite, Paula Castillo

LSU Doctoral Dissertations

The Formosan subterranean termite, Coptotermes formosanus, is a eusocial insect species. Its members live in colonies consisting of reproductive (queen and king) and non-reproductive individuals (workers and soldiers). Olfaction is an essential sense for the social life of many insects. However, in termites, little is known about how olfactory cues are perceived in the peripheral sensory system (antennae) and processed in the central nervous system (brain) to elicit different behavioral responses across castes. In this study, we investigated the olfactory system in all castes (soldiers, workers, and reproductive alates), from the antennal and brain morphology to the antennal gene …

Integrating Cultivar Resistance And Entomopathogens For Pest Management Of Sweetpotato Weevil, Cylas Formicarius Elegantulus (Summers), Schyler M. Lee

LSU Master's Theses

Sweetpotato, Ipomoea batatas (L.) Lam, is the number one vegetable crop in Louisiana, producing 21,178 kg/ha in the year 2021. The sweetpotato weevil, Cylas formicarius elegantulus (Summers), is an economically important pest of sweetpotato. C. formicarius elegantulus females lay eggs into feeding holes on the storage root surface. Larvae then hatch and tunnel through the sweetpotato flesh where they complete their development. This cryptic-natured brentid can cause up to 100% yield loss when left unmanaged. The Louisiana Department of Agriculture and Forestry mandates protocols to limit C. formicarius elegantulus spread (e.g., clean seed, pheromone trapping, and quarantines); however, scheduled chemical …

Evaluation Of A Nutritional Calming Supplement For Stress Management In Beef Cattle, Randall Mallette

LSU Master's Theses

Two studies were conducted to determine the efficacy of two formulations of a nutritional calming product, Placid 1.0 and Placid 2.0, at keeping beef cattle in a calm state when exposed to environmental factors that put them into an excited state. In the pilot study, nine crossbred beef heifers were orally drenched daily for three days with 60 mL of their respective treatments, pen scores and exit scores were recorded, and blood was collected for cortisol analysis. There were no treatment effects for either treatment on any of the measured behavioral parameters or serum cortisol concentrations.

The products were …

Impact Of Blood Flow Restricted Resistance Training On Skeletal Muscle Strength, Hypertrophy, Fatigue, Mitochondrial Response, And Activation, Brett Davis

LSU Doctoral Dissertations

Abstract

Blood flow restricted resistance exercise (BFR-RE) is a novel method that is effective at increasing strength and hypertrophy using much lower loads than the higher loads typical in progressive resistance exercise. However, the effects of BFR-RE on skeletal muscle fatigue, mitochondrial response, and activation are still being explored. This dissertation will discuss the impacts of BFR-RE, how it affects college-aged individuals that are trained and untrained, and the effects of BFR-RE on skeletal muscle fatigue, mitochondrial response, and activation.

The first study examined the effects of 6-weeks of low load blood flow restricted resistance exercise (LLBFR) on muscular strength, …

Eating Disorders In Weight-Related Therapy (Edit): Protocol For A Systematic Review With Individual Participant Data Meta-Analysis Of Eating Disorder Risk In Behavioural Weight Management, Hiba Jebeile, Natalie B. Lister, Sol Libesman, Kylie E. Hunter, Caitlin M. Mcmaster, Brittany J. Johnson, Louise A. Baur, Susan J. Paxton, Sarah P. Garnett, Amy L. Ahern, Denise E. Wilfley, Sarah Maguire, Amanda Sainsbury, Katharine Steinbeck, Lisa Askie, Caroline Braet, Andrew J. Hill, Dasha Nicholls, Rebecca A. Jones, Genevieve Dammery, Alicia M. Grunseit, Kelly Cooper, Theodore K. Kyle, Faith A. Heeren, Fiona Quigley, Rachel D. Barnes, Melanie K. Bean, Kristine Beaulieu, Maxine Bonham, Kerri N. Boutelle, Braulio Henrique Magnani Branco, Simona Calugi, Michelle I. Cardel, Kelly Carpenter

Clinical Research Faculty Publications

The Eating Disorders In weight-related Therapy (EDIT) Collaboration brings together data from randomised controlled trials of behavioural weight management interventions to identify individual participant risk factors and intervention strategies that contribute to eating disorder risk. We present a protocol for a systematic review and individual participant data (IPD) meta-analysis which aims to identify participants at risk of developing eating disorders, or related symptoms, during or after weight management interventions conducted in adolescents or adults with overweight or obesity. We systematically searched four databases up to March 2022 and clinical trials registries to May 2022 to identify randomised controlled trials of …

Preliminary Validation Of Digital Photography To Assess The Home Food Environment, Daniela Quan, Isaac Michael, Elizabeth Gollub

Faculty Publications

The home food environment (HFE), the availability and accessibility of foods and food products within the home, has a strong influence on healthy eating behaviors. Studies assessing the HFE commonly utilize a home food inventory (HFI) for data collection. However, this approach tends to be burdensome for participants. This study validated a low-burden digital photo method for assessing the home food environment and confirmed that this method is preferred by participants. Study participants completed an HFI, submitted photos of household foods, then identified preference for the HFI or photo reporting method. Researchers completed an HFI based on each participant’s photo …

Louisiana Agriculture Magazine, Summer 2023

Louisiana Agriculture

Rice, alligators and sugarcane are quintessential Louisiana products, and LSU AgCenter researchers and extension agents devote themselves to helping the producers who grow them. Economists are finding ways to improve the market for alligators while specialists focus on innovation in the sugar industry and creating new varieties of rice.

AgCenter researchers also have an eye on the natural world. They are protecting the roseau cane that thrives on the coast and the ironwood trees of Guam. All these efforts are detailed in this issue of Louisiana Agriculture magazine.

An Artemisia Scoparia Extract Attenuates Glucocorticoid-Induced Lipolysis In Adipocytes, Innocence Harvey, Jacqueline M. Stephens

Division of Basic Science Faculty Publications

Objective: Prescription glucocorticoid (GC) use is widespread across developed countries for the treatment of several inflammatory conditions. Elevated GCs are known to promote lipolysis and metabolic disorders. An extract of Artemisia scoparia (SCO) has been shown to reduce lipolysis and promote metabolic health but has not been investigated in the context of excess GCs. Our aim was to examine the effects of SCO on GC-induced lipolysis. Methods: Mature adipocytes were pretreated with vehicle or SCO, then exposed to either the synthetic GC dexamethasone (DEX) or tumor necrosis factor alpha (TNFα). Medium was collected and assayed for glycerol and fatty acids …

Obesogens And Obesity: State-Of-The-Science And Future Directions Summary From A Healthy Environment And Endocrine Disruptors Strategies Workshop, Jerrold J. Heindel, Jessica A. Alvarez, Ella Atlas, Matthew C. Cave, Vaia Lida Chatzi, David Collier, Barbara Corkey, Douglas Fischer, Michael I. Goran, Sarah Howard, Scott Kahan, Matthias Kayhoe, Suneil Koliwad, Catherine M. Kotz, Michele La Merrill, Tim Lobstein, Carey Lumeng, David S. Ludwig, Robert H. Lustig, Pete Myers, Angel Nadal, Leonardo Trasande, Leanne M. Redman, Matthew S. Rodeheffer, Robert M. Sargis, Jacqueline M. Stephens, Thomas R. Ziegler, Bruce Blumberg

Division of Basic Science Faculty Publications

On September 7 and 8, 2022, Healthy Environment and Endocrine Disruptors Strategies, an Environmental Health Sciences program, convened a scientific workshop of relevant stakeholders involved in obesity, toxicology, or obesogen research to review the state of the science regarding the role of obesogenic chemicals that might be contributing to the obesity pandemic. The workshop's objectives were to examine the evidence supporting the hypothesis that obesogens contribute to the etiology of human obesity; to discuss opportunities for improved understanding, acceptance, and dissemination of obesogens as contributors to the obesity pandemic; and to consider the need for future research and potential mitigation …

Current Discoveries And Future Implications Of Eating Disorders, Bing Feng, Jerney Harms, Emily Chen, Peiyu Gao, Pingwen Xu, Yanlin He

Division of Basic Science Faculty Publications

Eating disorders (EDs) are characterized by severe disturbances in eating behaviors and can sometimes be fatal. Eating disorders are also associated with distressing thoughts and emotions. They can be severe conditions affecting physical, psychological, and social functions. Preoccupation with food, body weight, and shape may also play an important role in the regulation of eating disorders. Common eating disorders have three major types: anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED). In some cases, EDs can have serious consequences for an individual’s physical and mental health. These disorders often develop during adolescence or early adulthood and affect …

Measuring In Vivo Adipose Tissue Kinetics In Humans Using The Deuterium (2h)-Labeling Approach, Dereck Kibodeaux, Jonathan Savoie, Eric Ravussin, Mark Fitch, Marc K. Hellerstein, Ursula White

Clinical Research Faculty Publications

White adipose tissue is a highly plastic organ that is necessary to maintain whole-body energy homeostasis. The adipose tissue mass and changes in the fat mass or distribution are regulated by changes in the synthesis and breakdown (i.e., turnover) of adipose cells and triacylglycerols. Evidence suggests that the manner and magnitude of subcutaneous adipose tissue expansion (i.e., hypertrophy vs. hyperplasia) and turnover can influence metabolic health, as adipogenesis has been implicated in the pathogenesis of obesity and related diseases. Despite the potential role of adipose turnover in human health, there is a lack of knowledge about the in vivo kinetics …

Current Status Of Us Soil Test Phosphorus And Potassium Recommendations And Analytical Methods, Sarah E. Lyons, Jason D. Clark, Deanna L. Osmond, Md Rasel Parvej, Austin W. Pearce, Nathan A. Slaton, John T. Spargo

Faculty Publications

Soil testing is the foundation of fertilizer recommendations in the United States. Fertilizer recommendations have primarily been developed by land-grant universities with limited coordination among programs. The individual state approach to develop fertilizer recommendations has resulted in discrepancies in recommended soil sampling protocols, soil analysis methods, and fertilizer recommendations at similar soil nutrient levels. A national survey was developed to summarize the status of soil testing and fertility work in the United States to inform future collaborative efforts among states and regions and identify opportunities to harmonize recommendation guidelines. Topics included relevant funding, multi-state collaborations, state soil-test recommendations and related …

Association Between Maternal And Infant Screen Time With Child Growth And Development: A Longitudinal Study, Chelsea L. Kracht, Leanne M. Redman, Jayne Bellando, Rebecca A. Krukowski, Aline Andres

Clinical Research Faculty Publications

Background: Sedentary screen time is an early, modifiable risk factor for obesity and poor child development. Objectives: To examine the relationship between maternal and infant screen time with child growth and development. Methods: Pregnant women were recruited for a cohort study related to maternal and infant development. Screen time was assessed in mothers during pregnancy, and subsequently in children at 3 months, 12 months, and 24 months of age. Child anthropometry was measured, and nuclear magnetic resonance quantified child fat mass. Fat mass index (FMI) was calculated. The Bayley Scales of Infant Development-III were used to assess child development. Linear …

Integrating Lipid Metabolism, Pheromone Production And Perception By Fruitless And Hepatocyte Nuclear Factor 4, Jie Sun, Wen Kan Liu, Calder Ellsworth, Qian Sun, Yufeng Pan, Yi Chun Huang, Wu Min Deng

Faculty Publications

Sexual attraction and perception are crucial for mating and reproductive success. In Drosophila melanogaster, the male-specific isoform of Fruitless (Fru), FruM, is a known master neuro-regulator of innate courtship behavior to control the perception of sex pheromones in sensory neurons. Here, we show that the non-sex-specific Fru isoform (FruCOM) is necessary for pheromone biosynthesis in hepatocyte-like oenocytes for sexual attraction. Loss of FruCOM in oenocytes resulted in adults with reduced levels of cuticular hydrocarbons (CHCs), including sex pheromones, and show altered sexual attraction and reduced cuticular hydrophobicity. We further identify Hepatocyte nuclear factor 4 (Hnf4) as a key target of …

Characteristics Of Yogurt And Culture Bacteria As Affected By Ingredients That Help Treat Leaky Gut, Ricardo Jose Santos Aleman

LSU Doctoral Dissertations

At least 100 million people have leaky gut syndrome. This syndrome is associated with multiple health problems such as diabetes, celiac disease, asthma, multiple sclerosis, and inflammatory bowel disease, costing more than $3 billion per year to treat. L-Glutamine, quercetin, slippery elm bark, marshmallow root, N-acetyl-d-glucosamine (NAG), licorice root, maitake mushrooms, and zinc orotate have been reported to help treat leaky gut.

The objectives were to explore the characteristics of yogurt and culture bacteria as affected by ingredients that help treat leaky gut. In yogurt, the pH, titratable acidity, syneresis, viscosity, color, Streptococcus thermophilus, Lactobacillus bulgaricus, yeast and mold and …

Food Insecurity Among Households With Children During The Early Months Of The Covid-19 Pandemic, Bailey Houghtaling, Megan M. Patton-López, Lindsey Haynes-Maslow, Nila Pradhananga, Lauri Andress, T. Elaine Prewitt, Annie Hardison-Moody, Justin D. Shanks, Michelle Grocke-Dewey, Eliza Webber, Denise Holston, Carmen Byker Shanks

Faculty Publications

Understanding impacts of the COVID-19 pandemic among households with children is necessary to design appropriate public health responses that protect food and nutrition security. The objecttive of this research was to understand predictors of food insecurity during the COVID-19 pandemic among households with at least one child (<18 >years), including whether foods reported as out-ofstock were associated with the likelihood of food insecurity. An online survey using validated measures and open-ended questions was distributed to a convenience sample in five states— Louisiana, Montana, North Carolina, Oregon, and West Virginia—during the early months of the COVID-19 pandemic (April through September of …

Nutrition Interventions Addressing Structural Racism: A Scoping Review, Matthew Greene, Bailey Houghtaling, Claire Sadeghzadeh, Molly De Marco, De'jerra Bryant, Randa Morgan, Denise Holston

Faculty Publications

African Americans experience high rates of obesity and food insecurity in part due to structural racism, or overlapping discriminatory systems and practices in housing, education, employment, health care and other settings. Nutrition education and nutrition-focused policy, systems and environmental changes may be able to address structural racism in the food environment. This scoping review aimed to summarise the available literature regarding nutrition interventions for African Americans that address structural racism in the food environment and compare them with the 'Getting to Equity in Obesity Prevention' framework of suggested interventions. An electronic literature search was conducted with the assistance of a …

Association Of Type 2 Diabetes Subgroups With Cognitive Status Without Modification From Lifestyle Intervention, Michael P. Bancks, James Lovato, Ashok Balasubramanyam, Mace Coday, Karen C. Johnson, Medha Munshi, Candida Rebello, Lynne E. Wagenknecht, Mark A. Espeland

Clinical Research Faculty Publications

Context: Type 2 diabetes is a risk factor for incident dementia but whether risk and treatment/prevention strategies differ by diabetes subgroup is unknown. Objective: We assessed (1) whether specific type 2 diabetes (T2D) subgroups are associated with mild cognitive impairment (MCI) or probable dementia (PD), and (2) whether T2D subgroups modified the association of the Action for Health in Diabetes (Look AHEAD) multidomain intensive lifestyle intervention (ILI) with MCI/PD. Methods: We included 3760 Look AHEAD participants with T2D and overweight or obesity randomly assigned to 10 years of ILI or diabetes support and education. We used k-means clustering techniques with …

Researching Covid To Enhance Recovery (Recover) Adult Study Protocol: Rationale, Objectives, And Design, Leora I. Horwitz, Tanayott Thaweethai, Shari B. Brosnahan, Mine S. Cicek, Megan L. Fitzgerald, Jason D. Goldman, Rachel Hess, S. L. Hodder, Vanessa L. Jacoby, Michael R. Jordan, Jerry A. Krishnan, Adeyinka O. Laiyemo, Torri D. Metz, Lauren Nichols, Rachel E. Patzer, Anisha Sekar, Nora G. Singer, Lauren E. Stiles, Barbara S. Taylor, Shifa Ahmed, Heather A. Algren, Khamal Anglin, Lisa Aponte-Soto, Hassan Ashktorab, Ingrid V. Bassett, Brahmchetna Bedi, Nahid Bhadelia, Christian Bime, Marie Abele C. Bind, Lora J. Black, Andra L. Blomkalns, Hassan Brim, Mario Castro, James Chan

Division of Basic Science Faculty Publications

Importance SARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or other health effects after the acute phase of infection; termed post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID. The characteristics, prevalence, trajectory and mechanisms of PASC are ill-defined. The objectives of the Researching COVID to Enhance Recovery (RECOVER) Multi-site Observational Study of PASC in Adults (RECOVER-Adult) are to: (1) characterize PASC prevalence; (2) characterize the symptoms, organ dysfunction, natural history, and distinct phenotypes of PASC; (3) identify demographic, social and clinical risk factors for PASC onset and recovery; and (4) define the biological mechanisms underlying PASC pathogenesis. …

Impact Of Zein And Lignin-Plga Biopolymer Nanoparticles Used As Pesticide Nanocarriers On Soybean Growth And Yield Under Field Conditions, Colin A.R. Bonser, Jaya Borgatta, Jason C. White, Carlos E. Astete, Cristina M. Sabliov, Jeffrey A. Davis

Faculty Publications

Nanoparticles are being utilized in agriculture as fertilizers, pesticides, and agrochemical-carriers. Designed to be biocompatible and degradable, biopolymer nanoparticles were developed as an alternative to metallic nanoparticles, and though safe-by-design, polymeric nanoparticles must be field-tested prior to largescale use. Several field studies were conducted to observe detrimental effects of biopolymer nanoparticles on plant growth and yield using soybean, Glycine max (L.) Merr., as a model system. Biopolymer nanoparticles made from lignin or zein were applied as seed treatments to soybean seeds or as foliar sprays (zein only) to soybean plants. Studies using biopolymer nanoparticle seed treatments (nano-STs) measured the germination …

Black Soldier Fly Frass Supports Plant Growth And Reduces Nitrogen Leaching During Coleus Production, Jeffrey Beasley, Jeff Kuehny, Thanos Gentimis, Jeb Fields

Faculty Publications

Industrial insect rearing is expected to increase as a feedstock to meet growing global food demand. This will lead to greater production of insect excreta known as frass, a nutrient-dense organic material that has shown promise as a natural fertilizer source with potential environmental benefits. In this study, black soldier fly (Hermetia illucens) frass (BSFF) was compared with a synthetic fertilizer (SF) during production of containerized ornamentals grown under greenhouse conditions. Fertilizers were incorporated into a bark-based substrate at 0, 0.1, 0.2, or 0.3 kg.m–3 nitrogen (N) planted with coleus (Plectranthus scutellarioides) plugs. Growth index, shoot dry weight, and leaf …