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Inhibition And Nucleic Acid Binding Studies Of The Carboxyltransferase Component Of Bacterial Acetyl-Coa Carboxylase, Brian Benson Jan 2011

Inhibition And Nucleic Acid Binding Studies Of The Carboxyltransferase Component Of Bacterial Acetyl-Coa Carboxylase, Brian Benson

LSU Doctoral Dissertations

Acetyl-CoA carboxylase is an essential enzyme, as it catalyzes the first committed and regulated step in fatty-acid biosynthesis in all organisms excepting few Archaea and Eubacteria. Acetyl-CoA carboxylase from gram-negative and gram-positive bacteria is a multifunctional enzyme composed of three separate proteins. The carboxyltransferase subunit catalyzes the transfer of a carboxyl group from carboxybiotin to acetyl-CoA, forming malonyl-CoA. The crystal structure of the Escherichia coli (E. coli) carboxyltransferase component of acetyl-CoA carboxylase revealed a unique Zn-domain, presumed to mediate nucleic acid binding, that is absent in the eukaryotic enzyme. Notably, the Zn-domain, adjacent to the active site of carboxyltransferase, makes …

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Advanced Management Of The Mexican Rice Borer (Eoreuma Loftini) In Sugarcane, Blake Emerson Wilson Jan 2011

Advanced Management Of The Mexican Rice Borer (Eoreuma Loftini) In Sugarcane, Blake Emerson Wilson

LSU Master's Theses

Insecticide, greenhouse and varietal resistance experiments were conducted in Texas to develop management tactics for the Mexican rice borer, Eoreuma loftini (Dyar), sugarcane. A 3-treatment, large plot aerial application study was set up in 5 commercial sugarcane fields (35-84 acres) to evaluate the utilization of pheromone traps to improve chemical control strategies for E. loftini during 2009 and 2010 growing seasons. A threshold of 20-25 moths/trap/wk was used as an indicator to initiate monitoring for E. loftini larval infestations. Larval infestations were directly related to the no. of moths/trap/wk (R2=0.71). Reductions in borer injury and adult emergence (60% and 40% …

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Demography, Paleopathology, And Health Status Of The Moche Remains In Huambacho, Peru: A Comprehensive Osteological Analysis, Emily Grace Jan 2011

Demography, Paleopathology, And Health Status Of The Moche Remains In Huambacho, Peru: A Comprehensive Osteological Analysis, Emily Grace

LSU Master's Theses

The Moche civilization, which thrived in northern Peru from AD 100-800, influenced a vast area that extended to the southernmost monumental site of Pañamarca. Huambacho, an archaeological site in the Nepeña Valley, which dates to the Early Horizon (600-200 cal BC), has yielded multiple Moche graves uncovered by the Proyecto Huambacho (2003-2004). The graves provide the first evidence of Moche presence outside of the neighboring Pañamarca monumental complex. This research entailed the osteological analysis of eleven individuals from nine Moche grave contexts at Huambacho, including the analysis of demographic features, pathology, trauma, and antemortem cultural modifications. Methodology included the visual …

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Changes In Select Phenolic Compounds During Ethanol Fermentation And Acetification Of Raspberry, Blueberry And Persimmon, Yen-Ping Tan Jan 2011

Changes In Select Phenolic Compounds During Ethanol Fermentation And Acetification Of Raspberry, Blueberry And Persimmon, Yen-Ping Tan

LSU Master's Theses

Polyphenols are major dietary components in fruits and vegetables. Many research and epidemiological studies have reported that phenolic compounds, such as anthocyanins, may have a protective effect against various degenerative diseases. Phenolics in grape wine have been extensively studied but information on changes of phenolics in wine and vinegar made from other fruit crops is limited, however. This research started with the objective of determining the effect of proteases in preventing phenolic and, specifically, anthocyanin degradation in the ethanolic fermentation of black raspberries to reduce sugar content. The results of this study led to investigations of changes of other polyphenols …

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Spray Drying Technology For The Production And Processing Of Microencapsulated Omega-3 Fish Oil With Egg Powder, Kevin Estuardo Mis Solval Jan 2011

Spray Drying Technology For The Production And Processing Of Microencapsulated Omega-3 Fish Oil With Egg Powder, Kevin Estuardo Mis Solval

LSU Master's Theses

Protein with essential amino acids is required for recovering, repairing, and building muscles after intensive exercise. A powder produced with egg white (EW) (high quality protein) and fish oil (menhaden (Brevoortia patronus) (MO) oil or salmon oil (SO)) with high DHA and EPA content should be particularly beneficial for athletes. The objective of this study was to develop microencapsulated omega-3 fatty acids fortified EW powders. Two stable emulsions were prepared with 3.43% (MO) or (SO), 56.21% EW, and 40.36% water (E-MO-EW and E-SO-EW). An EW with water solution (without fish oil) (E-EW) was prepared as a control. Two emulsions (E-MO-EW; …

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Inhibitory Effects Of Berry Anthocyanins On Palmitic Acid- Or Lipopolysaccharide- Induced Inflammation In Human Preadipocytes, Chenfei Gao Jan 2011

Inhibitory Effects Of Berry Anthocyanins On Palmitic Acid- Or Lipopolysaccharide- Induced Inflammation In Human Preadipocytes, Chenfei Gao

LSU Master's Theses

Obesity is an inflammatory disease associated with the development and progression of chronic degenerative diseases including insulin resistance, cardiovascular disease (CVD), type 2 diabetes mellitus (T2DM), and cancer. Circulating free fatty acid (FFA) are known risk factors promoting inflammation that can lead to CVD. Pre/adipocytes are known storage of low grade inflammatory biomarkers associated with obesity. However, the effects of dietary anthocyanins on inflammatory biomarkers in preadipocytes have not been reported. Berries are rich sources of naturally occurring antioxidant polyphenolics. There is increasing interest in the ability of berry anthocyanins to provide health benefits against obesity. Anthocyanins were isolated from …

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Use Of Condensed Tannins Supplementation And Inorganic Copper As Deworming Agents In Naturally Infected Ewes And Lambs, Moara De Santana Martins Jan 2011

Use Of Condensed Tannins Supplementation And Inorganic Copper As Deworming Agents In Naturally Infected Ewes And Lambs, Moara De Santana Martins

LSU Master's Theses

Sheep production is an important socioeconomic activity for the small producers and it can represent their primary income source. Gastrointestinal parasites have become the principal limiting factor for this industry around the world, especially because of the anthelmintic resistance phenomenon that has been increasing worldwide. The negligent use of anthelmintics has been reported as the main factor in the development of resistance. Among the parasites that infect sheep, H. contortus is considered the most harmful and also the parasite responsible for the fastest development of nematode resistance in small ruminants. Due to the economic impact this parasite may bring upon …

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Production Of Spray-Dried Honey Powder And Its Application In Bread, Ahalya Kosal Ram Jan 2011

Production Of Spray-Dried Honey Powder And Its Application In Bread, Ahalya Kosal Ram

LSU Master's Theses

Honey is a natural sweetener with various beneficial properties including anti-oxidant and anti-microbial activity. Retrograded starch is known to have hypocholesterolemic effects and act to inhibit fat accumulation. Honey powder produced using retrograded starch can be used as an alternative to sucrose in many bakery products like bread. The objectives of this study were to produce a honey powder containing retrograded starch, characterize the powder and use it as an alternative to sucrose in bread formulations. The honey powder was produced by spray drying honey using retrograded starch as a drying agent. The spray dried honey powder was characterized for …

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Costs And Benefits Of Induced Responses In Soybean, Amanda K. Accamando Jan 2011

Costs And Benefits Of Induced Responses In Soybean, Amanda K. Accamando

LSU Master's Theses

Herbivorous insects are known to negatively impact plant fitness, such that plants have evolved defense strategies to reduce the preference and performance of herbivores on those plants. However, a plant’s investment in defense may be costly when herbivores are absent from the environment. Defense traits that are induced only upon herbivory can mitigate costs associated with defense maintenance. Although costs and benefits of induced responses are generally assumed, empirical evidence for them is equivocal. We examined the fitness costs and benefits of jasmonic acid-induced responses by soybean (Glycine max L. Merr.) in the absence and presence of soybean loopers (Chrysodeix …

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Evaluation Of Selected Plant Products As Dietary Protein Sources For Florida Pompano (Trachinotus Carolinus), Gregory Lech Jan 2011

Evaluation Of Selected Plant Products As Dietary Protein Sources For Florida Pompano (Trachinotus Carolinus), Gregory Lech

LSU Master's Theses

Profitability of aquaculture enterprises worldwide has been affected by rising fish meal prices. Plant proteins are promising replacements for fish meal because of their lower cost and worldwide availability. The goal of this research was to provide nutritional information for the development of all-plant diets for Florida pompano by evaluating growth of fish fed soy-based, fish-meal-free diets and assessing the nutritional value of several plant protein sources. In the first experiment, juvenile Florida pompano were fed five, soy-based, fish-meal-free diets containing graded levels of soybean meal (SBM, or M) at 0, 20, 25, 30, or 35%, with the remaining protein …

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Temporal Changes Of Coastal Community Resilience In The Gulf Of Mexico Region, Kenan Li Jan 2011

Temporal Changes Of Coastal Community Resilience In The Gulf Of Mexico Region, Kenan Li

LSU Master's Theses

The Gulf of Mexico Region is a region where coastal hazards are frequently occurring. To study the resilience of the counties along the Gulf of Mexico is of great importance to its sustainable planning and development. It also plays a huge role in coastal hazard mitigation. This study assesses the temporal changes of coastal community resilience of 132 counties along the Gulf of Mexico. The basic analytical framework to assess resilience consists of three dimensions (exposure, damage, and recovery) and two relationships (vulnerability and adaptability). Vulnerability refers to the relationship between exposure and damage, whereas the relationship between damage and …

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Stochastic Modelling Of Eukaryotic Cell Cycle, Murali Krushna Koneru Jan 2011

Stochastic Modelling Of Eukaryotic Cell Cycle, Murali Krushna Koneru

LSU Master's Theses

Stochastic models are developed to capture the inherent stochasticity of the biochemical networks associated to many biological processes. The objective of the present thesis is to present a detailed picture of stochastic approach for the mathematical modeling of eukaryotic cell cycle, to demonstrate an important application of such model in chemotherapy and to present a methodology for selecting the model parameters. The stochastic cell cycle model, developed using stochastic chemical kinetics approach, leads to the formation of an infinite dimensional differential equation in probabilities of system being in a specific state. Using Monte Carlo simulations of this model, dynamics of …

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A Systematic Study Of Xylella Fastidiosa Strains Isolated From Pecan, Grapevine, Oleander, And Sycamore In Louisiana, Rebecca Ann Melanson Jan 2011

A Systematic Study Of Xylella Fastidiosa Strains Isolated From Pecan, Grapevine, Oleander, And Sycamore In Louisiana, Rebecca Ann Melanson

LSU Master's Theses

Xylella fastidiosa causes disease in a number of economically important crops and landscape shrubs and trees including grapevine, citrus, oleander, and sycamore. In pecan, X. fastidiosa causes pecan bacterial leaf scorch (PBLS), which leads to defoliation and reduces nut yield. No economically effective treatments are available for PBLS. In order to improve PBLS management practices, it is necessary to determine the subspecies of X. fastidiosa strains that infect pecan so potential sources of inoculum can be identified. Multiprimer PCR and phylogenetic analyses using nucleotide sequence data from the 16S-23S rDNA intergenic transcribed spacer (ITS) region and pglA consistently identified strains …

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Comparison Of Disk Diffusion, Agar Dilution, And Broth Microdiultion For Antimicrobial Susceptibility Testing Of Five Chitosans, Lin Jiang Jan 2011

Comparison Of Disk Diffusion, Agar Dilution, And Broth Microdiultion For Antimicrobial Susceptibility Testing Of Five Chitosans, Lin Jiang

LSU Master's Theses

Chitosan is a polysaccharide biopolymer with excellent biocompatibility, biodegradability, and low toxicity, which allows for potential wide applications. Recently, antimicrobial activities of chitosan against foodborne pathogens have been studied; many used disk diffusion to determine the activity. However, this method is unable to obtain minimal inhibitory concentrations (MICs), i.e., not quantitative. The objective of this study was to compare disk diffusion with agar dilution and broth microdilution, two quantitative methods used routinely in clinical laboratories, to determine MICs of chitosan against foodborne pathogens. Five chitosan compounds with molecular weights ranging between 43 and 1,100 kDa were tested against 36 representative …

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Characterization Of The Subcortical Interactions Between Larvae Of The Southern Pine Sawyer Monochamus Titillator (F.) And The Larvae Of The Southern Pine Beetle Guild Using Molecular Gut Analyses, Erich N. Schoeller Jan 2011

Characterization Of The Subcortical Interactions Between Larvae Of The Southern Pine Sawyer Monochamus Titillator (F.) And The Larvae Of The Southern Pine Beetle Guild Using Molecular Gut Analyses, Erich N. Schoeller

LSU Master's Theses

The southern pine beetle guild (Coleoptera: Curculionidae: Scolytinae) is arguably the most destructive group of forest pests in the Southeastern United States. Laboratory assays suggest that larvae of wood borer associates from the genus Monochamus (Coleoptera: Cerambycidae) may be facultative intraguild predators of southern pine beetle guild. In this study the dynamics of the subcortical interactions between M. titillator (F.) and members of the southern pine beetle guild were examined using PCR-based molecular gut content analyses. Species-specific PCR primer sets were developed to work under multiplex PCR conditions to detect DNA of members of southern pine beetle guild in the …

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Comparison Of Thermally Pasteurized And Ultrasonically Pasteurized Blueberry Juice (Vaccinium Corymbosum) And An Investigation Of Blueberry Juice Effect On Lipid Oxidation During Microencapsulation Of Poly-Unsaturated Fish Oils, Fathima Waheeda Mohideen Jan 2011

Comparison Of Thermally Pasteurized And Ultrasonically Pasteurized Blueberry Juice (Vaccinium Corymbosum) And An Investigation Of Blueberry Juice Effect On Lipid Oxidation During Microencapsulation Of Poly-Unsaturated Fish Oils, Fathima Waheeda Mohideen

LSU Master's Theses

Blueberries have received considerable attention due to their content of health promoting compounds such as polyphenols and anthocyanins. Thermal pasteurization (TP) is known to cause degradation of anthocyanins and juice color. Microencapsulation, particularly with incorporation of blueberry antioxidants, can improve the stability of menhaden (MO) and salmon (SO) fish oils rich in omega-3 fatty acids. The objectives of this research were to study the effect of TP and continuous ultrasonication processing on the microbiological, chemical and physical properties of blueberry juice (BJ) and to determine the effect of BJ on MO and SO lipid oxidation during microencapsulation. Fresh blueberries were …

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Effects Of Row Spacing And Debris Distribution On Small Mammal And Vegetation Communities In Newly Established Loblolly Pine Plantations, Louisiana, Joshua Lee Grace Jan 2011

Effects Of Row Spacing And Debris Distribution On Small Mammal And Vegetation Communities In Newly Established Loblolly Pine Plantations, Louisiana, Joshua Lee Grace

LSU Master's Theses

Commercial pine (Pinus spp.) forests in the southeastern United States are key to providing fiber for global wood supply needs. Concern has arisen over possible effects of intensive forest management techniques, including row spacing and distribution of woody debris after logging, on plant and wildlife communities. Therefore, we quantified response of plant and small mammal communities in replanted loblolly pine (P. taeda) stands to mechanical site preparation including 2 levels of row spacing and 2 methods of distributing woody debris following harvest in north and southeastern Louisiana, USA. Sites (n=16) were prepared with a combination of row spacing between planting …

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Sensory Discrimination Testing With Children, Karen Melissa Garcia Jan 2011

Sensory Discrimination Testing With Children, Karen Melissa Garcia

LSU Doctoral Dissertations

Literature concerning children’s performance in sensory discrimination methods is not as extensively published as performance with adults. Therefore, in this dissertation children’s performance in discrimination methods was investigated. First, performance in the triangle and 3-AFC methods was explored with children 6 to 12 years old. The paradox of discriminatory non-discriminators states that the proportion of correct responses in the 3-AFC method will be higher than that of the triangle. However, Thurstonian theory predicts that despite the difference in proportions of correct responses the degree of difference between the stimuli will be similar. The paradox and the Thurstonian predictions were challenged …

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Building Children's Liking And Preferences For Fruits And Vegetables Through School-Based Interventions, Anantha Padmaja Lakkakula Jan 2011

Building Children's Liking And Preferences For Fruits And Vegetables Through School-Based Interventions, Anantha Padmaja Lakkakula

LSU Doctoral Dissertations

Children’s food preferences play a major role in their food choices and consumption. The objectives of these studies were to examine the relationship between children’s preferences for fruits and vegetables (FV) and their weight status and to increase children’s liking of FV by offering repeated opportunities to taste less liked items. A representative sample of elementary school children (1st, 3rd, 4th, and 5th grades) were recruited in the three interventions. In the first study, 341 fourth- and fifth-grade children (43% boys; 68% 4th graders) were measured for height and weight and completed a survey which sought their preferences for 38 …

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Resistant Starch In The Diet Of Rodents Promotes An Increase In Fermentation And A Reduction In Body Fat In An Animal Model Of Dietary Obesity, Jason Andrew Charrier Jan 2011

Resistant Starch In The Diet Of Rodents Promotes An Increase In Fermentation And A Reduction In Body Fat In An Animal Model Of Dietary Obesity, Jason Andrew Charrier

LSU Master's Theses

In previous studies, in has been observed that the addition of resistant starch (RS) in the diet of rodents, a non-digestible fermentable fiber, promotes increases in markers of fermentation and improvements in body weight and body fat analysis when incorporated into low to moderate fat diets. This study investigated whether the same beneficial effects observed with RS addition in these lower fat diets could be obtained in a high fat diet, and if the type of fatty acid consumed in the diet makes a difference in markers of fermentation and body fat. Sprague Dawley rats (n=96) were fed as weight …

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Intravenous Injection Of Insulin For Measuring Insulin Sensitivity In Horses: Effects Of Epinephrine, Feeding Regimen, And Supplementation With Cinnamon For Fish Oil, Lisa Rosalee Earl Jan 2011

Intravenous Injection Of Insulin For Measuring Insulin Sensitivity In Horses: Effects Of Epinephrine, Feeding Regimen, And Supplementation With Cinnamon For Fish Oil, Lisa Rosalee Earl

LSU Master's Theses

Seven experiments were performed to assess the use of glucose responses to insulin injections as a means of estimating insulin sensitivity in horses; to compare the insulin sensitivities of normal horses vs. those displaying hyperleptinemia; and to put this method into practical application. Experiment 3.1 examined dose-responses in mares of potentially different insulin sensitivities. Recombinant human insulin was injected at doses of 8, 20, 50, and 125 mU/kg BW, as needed, to estimate the dose of insulin causing a 50% decrease in glucose concentrations (ED50). Five mares each of low leptin concentrations (LL) and low BCS, LL and high BCS, …

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Resemblance In Dietary Intakes Of Snacks, Sweets, Fruit, Vegetables, Energy, Macronutrients, And Selected Micronutrients Among Mother-Child Dyads From Families With Limited Incomes, Kathryn Wroten Jan 2011

Resemblance In Dietary Intakes Of Snacks, Sweets, Fruit, Vegetables, Energy, Macronutrients, And Selected Micronutrients Among Mother-Child Dyads From Families With Limited Incomes, Kathryn Wroten

LSU Master's Theses

The objective of these studies was to determine the association between dietary intakes of selected food groups, macronutrients, and micronutrients in mother-child dyads. This was a secondary analysis of data on low-income Black, Hispanic, and White children 3-5 years-old (y) participating in Head Start (HS) (n=650), and their mothers. Mothers served as a proxy for their child, and self-reported intake during a multiple-pass 24-hour recall interview for one weekend day. One weekend day was chosen since children attended HS during the week, and mothers may not know what their children consumed outside the home. Data were collected on children’s and …

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Effects Of Resistant Starch In Milk Replacer On Health And Performance In Neonatal Holstein Heifer Calves, Bethany Leann Fisher Jan 2011

Effects Of Resistant Starch In Milk Replacer On Health And Performance In Neonatal Holstein Heifer Calves, Bethany Leann Fisher

LSU Master's Theses

Forty-two female Holstein calves were assigned to one of three treatments at d 2 of age to study the effects of adding resistant starch (RS) to the milk replacer on health and performance. Treatments were control (0g RS), 4g RS, or 8g RS mixed into the reconstituted milk replacer. Calves were housed in individual calf hutches and fed milk replacer once daily until d 42 of age. Water and an 18% crude protein calf starter were offered ad libitum beginning d 3 throughout the duration of the 56 d trial. Calves remained in their hutches until d 56 of age …

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Utilizing Near-Infrared Spectroscopy To Detect Sodium Tripolyphosphate In Treated Penaeus Aztecus And Setiferus Shrimp, Alisa Marlene Todd Jan 2011

Utilizing Near-Infrared Spectroscopy To Detect Sodium Tripolyphosphate In Treated Penaeus Aztecus And Setiferus Shrimp, Alisa Marlene Todd

LSU Master's Theses

Applying sodium tripolyphosphate to shrimp may cause excess water absorption and has become a major concern to phosphate producers, the consumer and regulatory agencies, such as, the United States Food and Drug Administration. The objective of this study was to examine Near Infrared (NIR) spectroscopy as a nondestructive and rapid method of detecting shrimp treated with sodium tripolyphosphate solutions of varying concentrations and treatment times. Wild caught Penaeus setiferus and aztecus Louisiana gulf coast shrimp were submerged in distilled water, 2.5% sodium tripolyphosphate (STPP), and 5% sodium tripolyphosphate solutions for 30, 60, 120, 240, 480, 960, 1920 minute time intervals. …

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Influences Of Landscape Characteristics On The Nesting Ecology Of Female Wild Turkeys And Behavior Of Raccoons, Michael E. Byrne Jan 2011

Influences Of Landscape Characteristics On The Nesting Ecology Of Female Wild Turkeys And Behavior Of Raccoons, Michael E. Byrne

LSU Doctoral Dissertations

Nest predation is the principle source of reproductive failure in many bird species. Understanding nest predation requires knowledge of interactions between landscape characteristics, and the ecology and behavior of birds and local nest predators. I studied nesting ecology and multi-scale habitat selection of female wild turkeys and the habitat selection and searching behaviors of raccoons, an important nest predator, in a bottomland hardwood forest in Louisiana. My objective was to evaluate the relationships between habitat, wild turkey nest site selection, and raccoon foraging behavior. I used first-passage time (FPT) analysis on nightly foraging tracks of raccoons during the turkey nesting …

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Assessment Of Targeting Accuracy Of A Low-Energy Stereotactic Radiosurgery Treatment For Age-Related Macular Degeneration, Phillip J. Taddei, Erik Chell, Steven Hansen, Michael Gertner, Wayne D. Newhauser Dec 2010

Assessment Of Targeting Accuracy Of A Low-Energy Stereotactic Radiosurgery Treatment For Age-Related Macular Degeneration, Phillip J. Taddei, Erik Chell, Steven Hansen, Michael Gertner, Wayne D. Newhauser

Faculty Publications

Age-related macular degeneration (AMD), a leading cause of blindness in the United States, is a neovascular disease that may be controlled with radiation therapy. Early patient outcomes of external beam radiotherapy, however, have been mixed. Recently, a novel multimodality treatment was developed, comprising external beam radiotherapy and concomitant treatment with a vascular endothelial growth factor inhibitor. The radiotherapy arm is performed by stereotactic radiosurgery, delivering a 16 Gy dose in the macula (clinical target volume, CTV) using three external low-energy x-ray fields while adequately sparing normal tissues. The purpose of our study was to test the sensitivity of the delivery …

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The Contribution Of Wildlife To Sustainable Natural Resource Utilization In Namibia: A Review, Diana L.Schalkwyk Van Schalkwyk, Kenneth W. Mcmillin, R. Corli Witthuhn, Louw C. Hoffman Dec 2010

The Contribution Of Wildlife To Sustainable Natural Resource Utilization In Namibia: A Review, Diana L.Schalkwyk Van Schalkwyk, Kenneth W. Mcmillin, R. Corli Witthuhn, Louw C. Hoffman

Faculty Publications

Namibia is the driest country in sub-Saharan Africa, but well known for its richness in species and sustainable natural resource utilization. The Namibian farming sector consists mainly of extensive farming systems. Cattle production contributes 54% of the livestock sector's production output, followed by sheep and goats (25%), hides and skins (9%), and other forms of agricultural production (12%). Namibia's freehold farmers have obtained ownership rights over land and livestock since the early 1900s; commercial rights over wildlife and plants were given to freehold farmers in 1967 and to communal farmers in 1996. Natural resource-based production systems then overtook agricultural production …

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Colony Breeding System Influences Cuticular Bacterial Load Of Formosan Subterranean Termite (Isoptera: Rhinotermitidae) Workers, Claudia Husseneder, Dawn M. Simms, Gabriel K. Aluko, Jennifer Delatte Dec 2010

Colony Breeding System Influences Cuticular Bacterial Load Of Formosan Subterranean Termite (Isoptera: Rhinotermitidae) Workers, Claudia Husseneder, Dawn M. Simms, Gabriel K. Aluko, Jennifer Delatte

Faculty Publications

The goal of this study was to test whether the breeding system and/or the degree of inbreeding of field colonies of the Formosan subterranean termite, Coptotermes formosanus, Shiraki (Isoptera: Rhinotermitidae) influences bacterial load on the cuticle of foraging workers. We enumerated bacterial load on the cuticle of groups of workers foraging in 20 inground monitoring stations surrounding the French Market in New Orleans, LA, and identified bacteria species using 16S rRNA gene sequencing. We used microsatellite genotyping to assign the 20 worker groups to seven simple family colonies (headed by a single pair of reproductives) and four extended family colonies …

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Variation In The Checkpoint Kinase 2 Gene Is Associated With Type 2 Diabetes In Multiple Populations, Kari E. North, Nora Franceschini, Christy L. Avery, Lisa Baird, Mariaelisa Graff, Mark Leppert, Jay H. Chung, Jinghui Zhang, Craig Hanis, Eric Boerwinkle, Kelly A. Volcik, Megan L. Grove, Thomas H. Mosley, Charles Gu, Gerardo Heiss, James S. Pankow, David J. Couper, Christie M. Ballantyne, W. H. Linda Kao, Alan B. Weder, Richard S. Cooper, Georg B. Ehret, Ashley A. O'Connor, Aravinda Chakravarti, Steven C. Hunt Dec 2010

Variation In The Checkpoint Kinase 2 Gene Is Associated With Type 2 Diabetes In Multiple Populations, Kari E. North, Nora Franceschini, Christy L. Avery, Lisa Baird, Mariaelisa Graff, Mark Leppert, Jay H. Chung, Jinghui Zhang, Craig Hanis, Eric Boerwinkle, Kelly A. Volcik, Megan L. Grove, Thomas H. Mosley, Charles Gu, Gerardo Heiss, James S. Pankow, David J. Couper, Christie M. Ballantyne, W. H. Linda Kao, Alan B. Weder, Richard S. Cooper, Georg B. Ehret, Ashley A. O'Connor, Aravinda Chakravarti, Steven C. Hunt

Faculty Publications

Identification and characterization of the genetic variants underlying type 2 diabetes susceptibility can provide important understanding of the etiology and pathogenesis of type 2 diabetes. We previously identified strong evidence of linkage for type 2 diabetes on chromosome 22 among 3,383 Hypertension Genetic Epidemiology Network (HyperGEN) participants from 1,124 families. The checkpoint 2 (CHEK2) gene, an important mediator of cellular responses to DNA damage, is located 0.22 Mb from this linkage peak. In this study, we tested the hypothesis that the CHEK2 gene contains one or more polymorphic variants that are associated with type 2 diabetes in HyperGEN individuals. In …

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Fresh Raspberry Phytochemical Extract Inhibits Hepatic Lesion In A Wistar Rat Model, Yan Liu, Ming Liu, Bin Li, Jin Lu Zhao, Chun Peng Zhang, Luo Qiang Lin, Hong Sheng Chen, Shu Jun Zhang, Jun Chao Jin, Lei Wang, Le Jing Li, Jia Ren Liu Nov 2010

Fresh Raspberry Phytochemical Extract Inhibits Hepatic Lesion In A Wistar Rat Model, Yan Liu, Ming Liu, Bin Li, Jin Lu Zhao, Chun Peng Zhang, Luo Qiang Lin, Hong Sheng Chen, Shu Jun Zhang, Jun Chao Jin, Lei Wang, Le Jing Li, Jia Ren Liu

Faculty Publications

Background. Red raspberry possesses potent antioxidant capacity and antiproliferative activity against cancer in vitro. Methods. The objective of this study was to determine the protective effects of raspberry 80% acetone extract in a rat hepatic lesions model induced by diethylnitrosamine (DEN). Rats were treated with the red raspberry extract (0.75, 1.5 or 3.0 g/kg of body weight) by gavage starting 2 h after DEN administration and continuing for 20 weeks. Results. A dose-dependent inhibition by red raspberry extract of DEN-induced hepatic nodule formation which stands for hepatic lesions was observed. Corresponding hepatic nodule incidence rates were 45.0, 40.0, 25.0 and …

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