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A Whole-Grain Diet Increases Whole-Body Protein Balance Compared With A Macronutrient-Matched Refined-Grain Diet, Jacob T. Mey, Jean Philippe Godin, Amanda R. Scelsi, Emily L. Kullman, Steven K. Malin, Shengping Yang, Z. Elizabeth Floyd, Alexander Poulev, Roger A. Fielding, Alastair B. Ross, John P. Kirwan Nov 2021

A Whole-Grain Diet Increases Whole-Body Protein Balance Compared With A Macronutrient-Matched Refined-Grain Diet, Jacob T. Mey, Jean Philippe Godin, Amanda R. Scelsi, Emily L. Kullman, Steven K. Malin, Shengping Yang, Z. Elizabeth Floyd, Alexander Poulev, Roger A. Fielding, Alastair B. Ross, John P. Kirwan

Division of Basic Science Faculty Publications

Background: There are limited data from randomized control trials to support or refute the contention that whole-grains can enhance protein metabolism in humans. Objectives: To examine: 1) the clinical effects of a whole-grain diet on whole-body protein turnover; 2) the cellular effects of whole-grains on protein synthesis in skeletal muscle cells; and 3) the population effects of whole-grain intake on age-related muscle loss. Methods: Adults with overweight/obesity (n = 14; age = 40 ± 7 y; BMI = 33 ± 5 kg/m2) were recruited into a crossover, randomized controlled trial (NCT01411540) in which isocaloric, macronutrient-matched whole-grain and refined-grain diets were …

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Bioactive Compounds From Artemisia Dracunculus L. Activate Ampk Signaling In Skeletal Muscle, B. Vandanmagsar, Y. Yu, C. Simmler, T. N. Dang, P. Kuhn, A. Poulev, D. M. Ribnicky, G. F. Pauli, Z. E. Floyd Nov 2021

Bioactive Compounds From Artemisia Dracunculus L. Activate Ampk Signaling In Skeletal Muscle, B. Vandanmagsar, Y. Yu, C. Simmler, T. N. Dang, P. Kuhn, A. Poulev, D. M. Ribnicky, G. F. Pauli, Z. E. Floyd

Division of Basic Science Faculty Publications

An extract from Artemisia dracunculus L. (termed PMI-5011) improves glucose homeostasis by enhancing insulin action and reducing ectopic lipid accumulation, while increasing fat oxidation in skeletal muscle tissue in obese insulin resistant male mice. A chalcone, DMC-2, in PMI-5011 is the major bioactive that enhances insulin signaling and activation of AKT. However, the mechanism by which PMI-5011 improves lipid metabolism is unknown. AMPK is the cellular energy and metabolic sensor and a key regulator of lipid metabolism in muscle. This study examined PMI-5011 activation of AMPK signaling using murine C2C12 muscle cell culture and skeletal muscle tissue. Findings show that …

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Exploring Text Mining For Recent Consumer And Sensory Studies About Alternative Proteins, Ziyang Chen, Cristhiam Gurdian, Chetan Sharma, Witoon Prinyawiwatkul, Damir D. Torrico Nov 2021

Exploring Text Mining For Recent Consumer And Sensory Studies About Alternative Proteins, Ziyang Chen, Cristhiam Gurdian, Chetan Sharma, Witoon Prinyawiwatkul, Damir D. Torrico

Faculty Publications

Increased meat consumption has been associated with the overuse of fresh water, under-ground water contamination, land degradation, and negative animal welfare. To mitigate these problems, replacing animal meat products with alternatives such as plant-, insect-, algae-, or yeast-fermented-based proteins, and/or cultured meat, is a viable strategy. Nowadays, there is a vast amount of information regarding consumers’ perceptions of alternative proteins in scientific outlets. Sorting and arranging this information can be time-consuming. To overcome this drawback, text mining and Natural Language Processing (NLP) are introduced as novel approaches to obtain sensory data and rapidly identify current consumer trends. In this study, …

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Maternal Gestational Diabetes And Childhood Hyperlipidemia, Xiaoyun Yang, Junhong Leng, Huikun Liu, Leishen Wang, Weiqin Li, Wei Li, Xilin Yang, Ming Liu, Gang Hu Nov 2021

Maternal Gestational Diabetes And Childhood Hyperlipidemia, Xiaoyun Yang, Junhong Leng, Huikun Liu, Leishen Wang, Weiqin Li, Wei Li, Xilin Yang, Ming Liu, Gang Hu

Population and Public Health Science Faculty Publications

Aims: Aim of this study is to assess dyslipidemia risk between children exposed to maternal gestational diabetes mellitus (GDM) and those not exposed. Methods: We recruited 1144 mother–child pairs (572 GDM and 572 non-GDM women matched by their offspring's age and sex). The age of offspring ranged from 3 to 9 years old. We used general linear models to compare mean values of different lipid profiles among children born to mothers with and without GDM. Logistic regression models were used to assess associations of maternal GDM with abnormal lipid profiles in offspring. Results: After adjustment for maternal and children's characteristics, …

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Virtual Traffic Signals: Safe, Rapid, Efficient And Autonomous Driving Without Traffic Control, Zhao Zhang, Feng Liu, Brian Wolshon, Yu Sheng Nov 2021

Virtual Traffic Signals: Safe, Rapid, Efficient And Autonomous Driving Without Traffic Control, Zhao Zhang, Feng Liu, Brian Wolshon, Yu Sheng

Faculty Publications

Connected and autonomous vehicles (CAV) will open the future to vast possibilities in transportation, most of which have yet to be imagined. As these new technologies emerge, they also have the potential to render many of today's most common transportation control methods irrelevant. In this paper, concepts of connected and autonomous are applied to coordinate and synchronize the arrival and departure of vehicles at intersections; effectively ending the need for traffic signals. Under a set of 'autonomous rules of operation', vehicles can be kept in near-continuous motion while also maintaining safe separation, creating a system of 'virtual traffic signal' (VTS). …

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How Object Storage Skills Relate To Language Development, Jessica Laurent Nov 2021

How Object Storage Skills Relate To Language Development, Jessica Laurent

Honors Capstones

No abstract provided.

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Evaluation Of Seasonal Heat Stress On Transcriptomic Profiles And Global Dna Methylation Of Bovine Oocytes, Fabian A. Diaz, Emilio J. Gutierrez-Castillo, Brittany A. Foster, Paige T. Hardin, Kenneth R. Bondioli, Zongliang Jiang Oct 2021

Evaluation Of Seasonal Heat Stress On Transcriptomic Profiles And Global Dna Methylation Of Bovine Oocytes, Fabian A. Diaz, Emilio J. Gutierrez-Castillo, Brittany A. Foster, Paige T. Hardin, Kenneth R. Bondioli, Zongliang Jiang

Faculty Publications

Heat stress affects oocyte developmental competence and is a major cause of reduced fertility in heat stressed cattle. Negative effects of heat stress on the oocyte have been observed at morphological, biochemical and developmental levels. However, the mechanisms by which heat stress affects the oocyte at the transcriptional and epigenetic levels remain to be further elucidated. Here we aimed to investigate the effect of heat stress on oocyte quality, transcriptomic profiles and DNA methylation of oocytes collected through the transition from spring to summer under Louisiana conditions. Summer season resulted in a lower number of high quality oocytes obtained compared …

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Using Digital Libraries To Engage The Whole Student: Culturally Sustaining Pedagogies, Trauma-Informed Classrooms, And Project-Based Learning, Alejandra Torres Oct 2021

Using Digital Libraries To Engage The Whole Student: Culturally Sustaining Pedagogies, Trauma-Informed Classrooms, And Project-Based Learning, Alejandra Torres

Journal of Critical Digital Librarianship

Engaging students with an online library does not have to be limited to research purposes only. This essay includes lesson plan ideas that use the Louisiana Digital Library to engage middle and high school students in ways that help amplify their curiosity and explore their identities. To ensure the lesson plans engage the whole student, I ground them in three components (culturally sustaining pedagogies, trauma-informed classrooms, and project-based learning) and seven core values. These lessons could be used alone as writing workshops or can be used to introduce or make connections to other concepts. The activities are adaptable to fit …

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Interactions Between Prepregnancy Overweight And Passive Smoking For Macrosomia And Large For Gestational Age In Chinese Pregnant Women, Dingyu Cui, Wen Yang, Ping Shao, Jing Li, Peng Wang, Junhong Leng, Shuo Wang, Enqing Liu, Juliana C.N. Chan, Zhijie Yu, Gang Hu, Xilin Yang Oct 2021

Interactions Between Prepregnancy Overweight And Passive Smoking For Macrosomia And Large For Gestational Age In Chinese Pregnant Women, Dingyu Cui, Wen Yang, Ping Shao, Jing Li, Peng Wang, Junhong Leng, Shuo Wang, Enqing Liu, Juliana C.N. Chan, Zhijie Yu, Gang Hu, Xilin Yang

Population and Public Health Science Faculty Publications

Introduction: Previous analysis showed that passive smoking and overweight were associated with an increased risk of gestational diabetes mellitus (GDM) in a synergistic manner, while GDM increased the risk of macrosomia/large for gestational age (LGA). This study aimed to examine any interactive effects between passive smoking and overweight/obesity on risk of macrosomia/LGA. Methods: From 2010 to 2012, 22,302 pregnant women registered for pregnancy at a primary hospital in Tianjin, China. Data were collected longitudinally; that is, from their first antenatal care visit, at the glucose challenge test (GCT) time (24-28 weeks of gestation) and at delivery. Passive smoking was self-reported. …

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Binary And Ternary Toxicological Interactions Of Clothianidin And Eight Commonly Used Pesticides On Honey Bees (Apis Mellifera), Yanhua Wang, Yu Cheng Zhu, Wenhong Li, Jianxiu Yao, Gadi V.P. Reddy, Lu Lv Oct 2021

Binary And Ternary Toxicological Interactions Of Clothianidin And Eight Commonly Used Pesticides On Honey Bees (Apis Mellifera), Yanhua Wang, Yu Cheng Zhu, Wenhong Li, Jianxiu Yao, Gadi V.P. Reddy, Lu Lv

Faculty Publications

Although many toxicological evaluations have been conducted for honey bees (Apis mellifera), most of these studies have only focused on the effects of individual chemicals. However, honey bees are usually exposed to pesticide mixtures under field conditions. In this study, we examined the effects of individual pesticides and mixtures of clothianidin (CLO) with eight other pesticides [carbaryl (CAR), thiodicarb (THI), chlorpyrifos (CHL), beta-cyfluthrin (BCY), gamma-cyhalothrin (GCY), tetraconazole (TET), spinosad (SPI) and indoxacarb (IND)] on honey bees using a feeding method. Toxicity tests of a 4-day exposure to individual pesticides revealed that CLO had the highest toxicity to A. mellifera, with …

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Anticipating And Adapting To The Future Impacts Of Climate Change On The Health, Security And Welfare Of Low Elevation Coastal Zone (Lecz) Communities In Southeastern Usa, Thomas Allen, Joshua Behr, Anamaria Bukvic, Ryan S.D. Calder, Kiki Caruson, Charles Connor, Christopher D’Elia, David Dismukes, Robin Ersing Oct 2021

Anticipating And Adapting To The Future Impacts Of Climate Change On The Health, Security And Welfare Of Low Elevation Coastal Zone (Lecz) Communities In Southeastern Usa, Thomas Allen, Joshua Behr, Anamaria Bukvic, Ryan S.D. Calder, Kiki Caruson, Charles Connor, Christopher D’Elia, David Dismukes, Robin Ersing

Faculty Publications

No abstract provided.

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Louisiana Agriculture Fall, 2021, Lsu Agcenter Oct 2021

Louisiana Agriculture Fall, 2021, Lsu Agcenter

Louisiana Agriculture

No abstract provided.

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Lsu Research Fall 2021, Louisiana State University And Agricultural And Mechanical College Oct 2021

Lsu Research Fall 2021, Louisiana State University And Agricultural And Mechanical College

Research Magazine

LSU Research is published annually by the Office of Research & Economic Development, Louisiana State University.

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Placental Adaptation To Maternal Malnutrition, M. Carey Satterfield, Ashley K. Edwards, Fuller W. Bazer, Kathrin A. Dunlap, Chelsie B. Steinhauser, Guoyao Wu Oct 2021

Placental Adaptation To Maternal Malnutrition, M. Carey Satterfield, Ashley K. Edwards, Fuller W. Bazer, Kathrin A. Dunlap, Chelsie B. Steinhauser, Guoyao Wu

Faculty Publications

Maternal malnutrition gives rise to both short- and long-term consequences for the survival and health of the offspring. As the intermediary between mother and fetus, the placenta has the potential to interpret environmental signals, such as nutrient availability, and adapt to support fetal growth and development. While this potential is present, it is clear that at times placental adaptation fails to occur resulting in poor pregnancy outcomes. This review will focus on placental responses to maternal undernutrition related to changes in placental vascularization and hemodynamics and placental nutrient transport systems across species. While much of the available literature describes placental …

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Leptin Receptor Signaling Is Required For Intact Hypoglycemic Counterregulation: A Study In Male Zucker Rats, Christopher D. Morrison, Marina A. Duvall, Cristal M. Hill, Redin A. Spann, David H. Mcdougal Oct 2021

Leptin Receptor Signaling Is Required For Intact Hypoglycemic Counterregulation: A Study In Male Zucker Rats, Christopher D. Morrison, Marina A. Duvall, Cristal M. Hill, Redin A. Spann, David H. Mcdougal

Division of Basic Science Faculty Publications

Hypoglycemia is a major barrier to clinical management of persons with diabetes. Emerging evidence supports a role for leptin in gating hypoglycemic counterregulation. This work demonstrates that male leptin receptor null, Zucker (fa/fa), rats display severe impairments in hypoglycemic counterregulation. Thus, augmenting leptin levels may have clinical utility for preventing hypoglycemia.

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Nest Survival Of Seaside Sparrows (Ammospiza Maritima) In The Wake Of The Deepwater Horizon Oil Spill, Megan E. Hart, Anna Perez-Umphrey, Philip C. Stouffer, Christine Bergeon Burns, Andrea Bonisoli-Alquati, Sabrina S. Taylor, Stefan Woltmann Oct 2021

Nest Survival Of Seaside Sparrows (Ammospiza Maritima) In The Wake Of The Deepwater Horizon Oil Spill, Megan E. Hart, Anna Perez-Umphrey, Philip C. Stouffer, Christine Bergeon Burns, Andrea Bonisoli-Alquati, Sabrina S. Taylor, Stefan Woltmann

Faculty Publications

In 2010, the Deepwater Horizon oil spill released an estimated 4.9 million barrels of oil into the Gulf of Mexico, damaging coastal ecosystems. Seaside Sparrows (Ammospiza maritima)—a year-round resident of Gulf Coast salt marshes—were exposed to oil, as shown by published isotopic and molecular analyses, but fitness consequences have not been clarified. We monitored nests around two bays in Plaquemines Parish, Louisiana, USA from 2012–2017 to assess possible impacts on the nesting biology of Seaside Sparrows. A majority of nests failed (76% of known-fate nests, N = 252 nests, 3521 exposure-days) during our study, and predation was the main cause …

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Carcass Yields And Physical-Chemical Meat Quality Characteristics Of Namibian Red Hartebeest (Alcelaphus Buselaphus) As Influenced By Sex And Muscle, Louwrens C. Hoffman, Diana L. Van Schalkwyk, Magdalena Muller, Tersia Needham, Kenneth W. Mcmillin Oct 2021

Carcass Yields And Physical-Chemical Meat Quality Characteristics Of Namibian Red Hartebeest (Alcelaphus Buselaphus) As Influenced By Sex And Muscle, Louwrens C. Hoffman, Diana L. Van Schalkwyk, Magdalena Muller, Tersia Needham, Kenneth W. Mcmillin

Faculty Publications

This study determined the carcass yields of red hartebeest from Namibia and compared the physical-chemical meat quality characteristics of six different muscles (biceps femoris, infraspinatus, longissimus thoracis et lumborum, semimembranosus, semitendinosus, and supraspinatus) for both males and females. Red hartebeest males were heavier (133.92 kg) than females (114.20 kg) but the average dressing percentage did not differ between the two sexes. Muscles from females had a lower mean shear force value of 3.59 kg/1.27 cm ø, compared to males (4.23 kg/1.27 cm ø). The most tender muscle was the infraspinatus of the female treatment group, while the semimembranosus of the …

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Atlas Of Receptor Genes Expressed By The Bovine Morula And Corresponding Ligand-Related Genes Expressed By Uterine Endometrium, Lei Sang, Yao Xiao, Zongliang Jiang, Niamh Forde, Xiuchun Cindy Tian, Patrick Lonergan, Peter J. Hansen Oct 2021

Atlas Of Receptor Genes Expressed By The Bovine Morula And Corresponding Ligand-Related Genes Expressed By Uterine Endometrium, Lei Sang, Yao Xiao, Zongliang Jiang, Niamh Forde, Xiuchun Cindy Tian, Patrick Lonergan, Peter J. Hansen

Faculty Publications

Regulation of the mammalian embryo involves cell-signaling molecules produced by the maternal oviduct and endometrium. Here, datasets on the transcriptome of the gestational Days 5 and 6 bovine morula and Day 5 maternal endometrium were examined to identify receptor genes expressed by the morula and expression of the corresponding ligand-related genes in the endometrium. A total of 175 receptor genes were identified in the morula, including 48 encoding for growth factors or WNT signaling molecules, 25 for cytokines and chemokines, 35 involved in juxtacrine and matricellular signaling and 25 encoding for receptors for small molecules. Some of the highly-expressed pairs …

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Hydrophobically Modified Polypeptoids And Uses Thereof, Donghui Zhang, Vijay T. John, Yueheng Zhang, Sunting Xuan Sep 2021

Hydrophobically Modified Polypeptoids And Uses Thereof, Donghui Zhang, Vijay T. John, Yueheng Zhang, Sunting Xuan

College of Science Patents

A variety of hydrophobically modified polypeptoids are provided. The hydrophobically modified polypeptoids can include a polyamide backbone having a random copolymer of two or more different types of repeat units, where one or more of the repeat units have nitrogen atom having a hydrophobic substituent attached thereto. Methods of making the hydrophobically modified polypeptoids are also provided, as well as uses of the hydrophobically modified polypeptoids, for example in liposomal drug delivery.

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A Modular Open-Technology Device To Measure And Adjust Concentration Of Sperm Samples For Cryopreservation, Nikolas C. Zuchowicz Sep 2021

A Modular Open-Technology Device To Measure And Adjust Concentration Of Sperm Samples For Cryopreservation, Nikolas C. Zuchowicz

LSU Master's Theses

Repositories for aquatic germplasm can safeguard the genetic diversity of species of interest to aquaculture, research, and conservation. The development of such repositories is impeded by a lack of standardization both within laboratories and across the research community. Protocols for cryopreservation are often developed ad hoc and without close attention to variables, such as sperm concentration, that strongly affect the success and consistency of cryopreservation. The wide dissemination and use of specialized tools and devices can improve processing reliability, provide data logging, produce custom hardware to address unique problems, and save costs, time, and labor. The goal of the present …

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Influence Of Planting Date, Maturity Group, Harvest Aids And Fungicide Application On Soybean (Glycine Max (L.) Seed Quality, Ana Priscila Campos Sep 2021

Influence Of Planting Date, Maturity Group, Harvest Aids And Fungicide Application On Soybean (Glycine Max (L.) Seed Quality, Ana Priscila Campos

LSU Master's Theses

Field studies evaluated the influence of planting date, maturity group, and harvest timing on soybean yield and seed quality at the LSU AgCenter Northeast (NERS), Macon Ridge, and Dean Lee Research Stations in 2018-2020. In addition, the influence of harvest aid and fungicide application on seed quality impact from delayed harvest and environment was investigated at NERS in 2019 and 2020 in both field and environmentally controlled growth chambers. Soybean yield was maximized when maturity group IV and V soybean varieties were planted between Mid-April and Mid-May. Earlier and later planting dates did not result in maximized yield. Planting date …

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Eating For Hunger Or Pleasure: A Serotonin Model, Zili Yan, Yanlin He, Xing Cai, Gang Shu, Yong Xu Sep 2021

Eating For Hunger Or Pleasure: A Serotonin Model, Zili Yan, Yanlin He, Xing Cai, Gang Shu, Yong Xu

Division of Basic Science Faculty Publications

No abstract provided.

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Efficient, Low-Cost Bridge Cracking Detection And Quantification Using Deep-Learning And Uav Images, Chao Sun, Xiangyu Meng, Joshua O. Ogbebor, Shaopan Guo Sep 2021

Efficient, Low-Cost Bridge Cracking Detection And Quantification Using Deep-Learning And Uav Images, Chao Sun, Xiangyu Meng, Joshua O. Ogbebor, Shaopan Guo

Publications

Many bridges in the State of Louisiana and the United States are working under serious degradation conditions where cracks on bridges threaten structural integrity and public security. To ensure structural integrity and public security, it is required that bridges in the US be inspected and rated every two years. Currently, this biannual assessment is largely implemented using manual visual inspection methods, which is slow and costly. In addition, it is challenging for workers to detect cracks in regions that are hard to reach, e.g., the top part of the bridge tower, cables, mid-span of the bridge girders, and decks. This …

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Trapping Soybean Looper (Lepidoptera: Noctuidae) In The Southeastern Usa And Implications For Pheromone-Based Research And Management, Daniel E. Fleming, Jeffrey A. Davis, Fred R. Musser, Silvana V. Paula-Moraes, Ronald C. Stephenson, Christopher A. Wheeler, Earl Eugene Ringpis, Tyler S. Crum, J. Khai Tran Sep 2021

Trapping Soybean Looper (Lepidoptera: Noctuidae) In The Southeastern Usa And Implications For Pheromone-Based Research And Management, Daniel E. Fleming, Jeffrey A. Davis, Fred R. Musser, Silvana V. Paula-Moraes, Ronald C. Stephenson, Christopher A. Wheeler, Earl Eugene Ringpis, Tyler S. Crum, J. Khai Tran

Faculty Publications

Novel strategies for the management of soybean looper, Chrysodeixis includens (Walker) (Lepidoptera: Noctuidae), are needed due to its increasing importance, costs, and challenges of management in soybeans (Glycine max [L.] Merr.; Fabaceae) in the Americas. Pheromone-mediated mating disruption may be 1 such novel strategy, but an effective tool for estimating mating disruption success must be found. The technique of trapping male moths using pheromone baited traps is a common method for assessing mating disruption technology. This paper reports on the testing of 2 trap types and 3 commercially available lures containing (Z)-7-dodecenyl acetate as the major active component. Trapping was …

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Managing Corpses From Different Castes In The Eastern Subterranean Termite, Jizhe Shi, Chi Zhang, Sirui Huang, Austin Merchant, Qian Sun, Chuan Zhou, Kenneth F. Haynes, Xuguo Zhou Sep 2021

Managing Corpses From Different Castes In The Eastern Subterranean Termite, Jizhe Shi, Chi Zhang, Sirui Huang, Austin Merchant, Qian Sun, Chuan Zhou, Kenneth F. Haynes, Xuguo Zhou

Faculty Publications

Corpse management is essential for social animals to maintain colony health. In the eastern subterranean termite, Reticulitermes flavipes, workers carry out undertaking behaviors to mitigate the risks associated with the dead. In this study, we hypothesized that termites would respond differently to the corpses from different castes based on their postmortem chemical signatures. To test this hypothesis, we 1) documented the behavioral responses of the workers toward corpses from different castes, and 2) profile the chemical signatures of these corpses. Corpses from all castes were retrieved inside the nests and cannibalized when they were decomposed <64 >h, regardless of the presence …

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Identifying Areas Of Overlap And Distinction In Early Lexical Profiles Of Children With Autism Spectrum Disorder, Late Talkers, And Typical Talkers, Eva Jiménez, Eileen Haebig, Thomas T. Hills Sep 2021

Identifying Areas Of Overlap And Distinction In Early Lexical Profiles Of Children With Autism Spectrum Disorder, Late Talkers, And Typical Talkers, Eva Jiménez, Eileen Haebig, Thomas T. Hills

Faculty Publications

This study compares the lexical composition of 118 children with autism spectrum disorder (ASD) aged 12 to 84 months with 4626 vocabulary-matched typically developing toddlers with and without language delay, aged 8 to 30 months. Children with ASD and late talkers showed a weaker noun bias. Additionally, differences were identified in the proportion of nouns and verbs, and in the semantic categories of animals, toys, household items and vehicles. Most differences appear to reflect the extent of the age differences between the groups. However, children with ASD produced fewer high-social verbs than typical talkers and late talkers, a difference that …

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Deep Belief Network Based Audio Classification For Construction Sites Monitoring, Michele Scarpiniti, Francesco Colasante, Simone Di Tanna, Marco Ciancia, Yong Cheol Lee, Aurelio Uncini Sep 2021

Deep Belief Network Based Audio Classification For Construction Sites Monitoring, Michele Scarpiniti, Francesco Colasante, Simone Di Tanna, Marco Ciancia, Yong Cheol Lee, Aurelio Uncini

Faculty Publications

In this paper, we propose a Deep Belief Network (DBN) based approach for the classification of audio signals to improve work activity identification and remote surveillance of construction projects. The aim of the work is to obtain an accurate and flexible tool for consistently executing and managing the unmanned monitoring of construction sites by using distributed acoustic sensors. In this paper, ten classes of multiple construction equipment and tools, frequently and broadly used in construction sites, have been collected and examined to conduct and validate the proposed approach. The input provided to the DBN consists in the concatenation of several …

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A 3d Printed Vitrification Device For Storage In Cryopreservation Vials, Yue Liu, Andy Lin, Terrence R. Tiersch, William Todd Monroe Sep 2021

A 3d Printed Vitrification Device For Storage In Cryopreservation Vials, Yue Liu, Andy Lin, Terrence R. Tiersch, William Todd Monroe

Faculty Publications

Sperm cryopreservation by vitrification is a promising approach for small-bodied animals such as zebrafish (Danio rerio). However, most vitrification tools adopted in aquatic research were initially designed for applications other than sperm (such as human embryo freezing) and, thus, pose challenges for adoption to sperm vitrification. Three-dimensional (3D) printing combined with open hardware sharing is an emerging strategy to address challenges in the development of cryo-preservation tools. The goal of this study was to develop a 3D printed Vitrification Device for Cryo-Vials (VDCV) that can be integrated with the existing vial storage systems. The VDCV combined the vitrification and handling …

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Pioglitazone Reverses Markers Of Islet Beta-Cell De-Differentiation In Db/Db Mice While Modulating Expression Of Genes Controlling Inflammation And Browning In White Adipose Tissue From Insulin-Resistant Mice And Humans, J. Jason Collier, Heidi M. Batdorf, Kaelan L. Merrifield, Thomas M. Martin, Ursula White, Eric Ravussin, David H. Burk, Chris R. Cooley, Michael D. Karlstad, Susan J. Burke Sep 2021

Pioglitazone Reverses Markers Of Islet Beta-Cell De-Differentiation In Db/Db Mice While Modulating Expression Of Genes Controlling Inflammation And Browning In White Adipose Tissue From Insulin-Resistant Mice And Humans, J. Jason Collier, Heidi M. Batdorf, Kaelan L. Merrifield, Thomas M. Martin, Ursula White, Eric Ravussin, David H. Burk, Chris R. Cooley, Michael D. Karlstad, Susan J. Burke

Division of Basic Science Faculty Publications

Obesity, insulin resistance, and type 2 diabetes contribute to increased morbidity and mortality in humans. The db/db mouse is an important mouse model that displays many key features of the human disease. Herein, we used the drug pioglitazone, a thiazolidinedione with insulin-sensitizing properties, to investigate blood glucose levels, indicators of islet β-cell health and maturity, and gene expression in adipose tissue. Oral administration of pioglitazone lowered blood glucose levels in db/db mice with a corresponding increase in respiratory quotient, which indicates improved whole-body carbohydrate utilization. In addition, white adipose tissue from db/db mice and from humans treated with pioglitazone showed …

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Fgf21 Prevents Low-Protein Diet-Induced Renal Inflammation In Aged Mice, Han Fang, Sujoy Ghosh, Landon C. Sims, Kirsten P. Stone, Cristal M. Hill, Denisha Spires, Daria V. Ilatovskaya, Christopher D. Morrison, Thomas W. Gettys, Krisztian Stadler Sep 2021

Fgf21 Prevents Low-Protein Diet-Induced Renal Inflammation In Aged Mice, Han Fang, Sujoy Ghosh, Landon C. Sims, Kirsten P. Stone, Cristal M. Hill, Denisha Spires, Daria V. Ilatovskaya, Christopher D. Morrison, Thomas W. Gettys, Krisztian Stadler

Division of Basic Science Faculty Publications

Low-protein (LP) diets extend lifespan through a comprehensive improvement in metabolic health across multiple tissues and organs. Many of these metabolic responses to protein restriction are secondary to transcriptional activation and release of FGF21 from the liver. However, the effects of an LP diet on the kidney in the context of aging has not been examined. Therefore, the goal of the current study was to investigate the impact of chronic consumption of an LP diet on the kidney in aging mice lacking FGF21. Wild-Type (WT; C57BL/6J) and FGF21 knockout (KO) mice were fed a normal protein diet (20% casein) or …

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