Digital Commons Network^™

Sagittal Abdominal Diameter And Abdominal Aortic Calcification Are Associated With Incident Major Adverse Cardiovascular Events: The Manitoba Bone Density Registry, Haftom N. Abraha, Abadi K. Gebre, Marc Sim, Cassandra Smith, Syed Zulqarnain Gilani, Zaid Ilyas, Fatima Zarzour, John T. Schousboe, Lisa M. Lix, Neil Binkley, Siobhan Reid, Barret A. Monchka, Douglas Kimelman, Joshua R. Lewis, William D. Leslie

Research outputs 2022 to 2026

BackgroundSagittal abdominal diameter (SAD), a measure of visceral adiposity, has been linked to major adverse cardiovascular events (MACE). However, the relationship between SAD and abdominal aortic calcification (AAC), a marker of subclinical vascular disease, and whether they independently and jointly predict MACE remains unclear.ObjectiveTo investigate whether weight-normalized SAD and AAC scored using a validated machine learning algorithm (ML-AAC24) are independently and jointly associated with incident MACE.MethodsSAD and ML-AAC24 were measured from dual-energy X-ray absorptiometry (DXA) posteroanterior and lateral spine images, respectively, from the Manitoba Bone Density registry.ResultsAmong 8806 individuals (mean age 75.1 ± 6.6 years, 93.9% women), 11.3% experienced MACE …

Do I Fit In Here? How Immigrants’ Endorsement Of Social Markers Is Related To Their Wellbeing In Three Migrant Receiving Societies, Justine Dandy, Chan Hoong Leong, Adam Komisarof, Travis Lim, Krystal Perkins

Research outputs 2022 to 2026

Social markers of acceptance are the attributes seen as important for immigrants to achieve or display in order to be accepted similarly to a local-born citizen. In research on constructions of national identity, factor analysis reveals a culture-specific, two-factor structure akin to the ethnic–civic distinction observed. In this paper, we extend this work by examining the relationship between social markers of acceptance and immigrants’ well-being in three national contexts: Australia, Japan, and the U.S. Specifically, in study 1 we examined the factor structure of social markers in non-immigrant samples in each context (Australia, n = 1357; Japan, n = 2000; …

Nursing Students' Evaluation Of Primary Health Care Clinical Placements - A Cross-Sectional Study, Debbie Procter, Megan Lee, Debbie Massey, Kylie Mccullough, Karen Strickland

Research outputs 2022 to 2026

Aim: Evaluate quality and satisfaction of nursing students' Primary Health Care clinical placements. Background: There is growing recognition of the need to expand the Primary Health Care nursing workforce, with positive clinical placement experiences considered essential for preparing and inspiring future careers in these settings; however, few graduate nurses choose this career path. Design: A cross-sectional study design using purposive sampling. Participants: Data were sourced from National Placement Evaluation Centre's 2023/2024 dataset using the validated PET–Nursing survey. The tool includes 20 items across two subscales - Clinical Environment and Learning Support, with the final item assessing overall placement satisfaction. Surveys …

Neuroprotective Effects Of Sorghum Polyphenol In Alzheimer’S Disease: In Vitro And In Silico Analyses, Rasheed A. Abdulraheem, Ralph N. Martins, Rajapandiyan Krishnamoorthy, Mohammad A. Alshuniaber, Prashant Bharadwaj, Zhaoyu Li, Ranil Coorey, Vijay Jayasena, Stuart K. Johnson, W. M.A.D.Binosha Fernando

Research outputs 2022 to 2026

Background/Objective: Accumulation of amyloid-beta (Aβ) senile plaques in the human brain is a major hallmark of Alzheimer’s disease (AD), which manifests as progressive decline in memory and cognitive functions and currently lacks effective disease-modifying therapies. Emerging evidence demonstrates that polyphenol-rich plant foods are potential complementary therapies for AD. Methods: In this study, we investigated crude polyphenol extracts (CPEs) and purified polyphenol extracts (PPEs) from three sorghum genotypes for their ability to inhibit Aβ42-induced toxicity in MC-65 cells. Thioflavin T fluorescence, cell viability, mitochondrial function, oxidative stress assays, and Western blotting, along with RNA sequencing and computational analyses, were used to …

Semantic Context Improvisational Retrieval-Augmented Generation For Empathic Conversational Ai, Sharjeel Tahir, Judith Johnson, Jumana Abu-Khalaf, Syed Afaq Ali Shah

Research outputs 2022 to 2026

A fundamental limitation of modern conversational AI is its limited capacity to demonstrate sustained empathy in long-form interactions. We propose SCIRAG (Semantic Context Improvisational Retrieval-Augmented Generation), a feedback-driven retrieval framework for adaptive empathic dialogue. It employs a dual-loop retrieval framework, iteratively optimizing a static counseling dataset through user metadata and feedback memory refinement. To enhance contextual alignment, we deploy retrieval adaptation, enabling the model to retain and leverage past conversational cues based on user preferences. When integrated with Mixtral-8x7B, SCIRAG improves human-rated empathic understanding by +1.26 points and empathic response by +1.00 point on the RoPE scale, while increasing acceptability …

The Contribution Of Adolescent Cardiovascular Disease Risk Factors To Vascular Stiffness And Cardiac Remodelling In Young Adults, Anne E. Barden, Lawrence J. Beilin, Nick S.R. Lan, Amro Sehly, Girish Dwivedi, Rae-Chi Huang, Brendan Adler, Trevor A. Mori

Research outputs 2022 to 2026

Aims: Early identification of abnormalities in vascular and cardiac structure offers an opportunity for intervention to reduce future cardiovascular disease (CVD). This study examined factors contributing to increased CVD risk from adolescence to young adulthood. Methods and results: Raine Study participants (n = 716) classified as low- or high-CVD risk using cluster analysis at 17 years were re-studied at 27 years. Outcomes at 27 years were vascular stiffness assessed by pulse wave velocity (PWV) and left ventricular mass index (LVMI), left ventricular (LV), right ventricular (RV), and left atrial (LA) myocardial strain and respective ejection fractions (EF) assessed by cardiac …

A Remarkable Diversity Of Syngnathid Fishes In A Highly Modified Large Coastal Embayment In The Southeastern Indian Ocean, Glenn I. Moore, Jenelle A. Ritchie, Georgia M. Nester, Glenn A. Hyndes, Alan J. Kendrick

Research outputs 2022 to 2026

Southern Australia supports a high diversity of fishes in the family Syngnathidae, which is recognised as globally threatened, facing threats from coastal development, over-exploitation and bycatch. In southwestern Australia, Cockburn Sound houses a large industrial port and naval defence assets with plans to substantially expand the port facilities but also sits within a recognised syngnathid ‘hotspot’. Using a broad array of data sources, including historical museum vouchers, published records, historical and contemporary observations from notebooks and diving surveys, historical and contemporary trawl surveys, citizen science observations and environmental DNA, we compiled 4839 records of syngnathid fishes from the embayment. Twenty-one …

Co-Design And Pilot Testing Of A Nurse-Led Gp-Supported Self-Management Intervention For Breast Cancer Survivors With Cardiovascular Diseases: A Study Protocol, Anu Correya, Jing Yu Tan, Xian Liang Liu, Daniel Bressington, Leah East, Tao Wang

Research outputs 2022 to 2026

Background/Objectives: Self-management intervention strategies are recommended to address the needs of breast cancer survivors (BCSs) who have cardiovascular diseases (CVDs). Despite the benefits, these strategies are often suboptimally implemented, resulting in inadequate cardiovascular management among BCS with CVDs. The project aims to develop a nurse-led and GP-supported self-management (NGPS) intervention to reduce cardiovascular risks in BCS with CVDs and evaluate its feasibility and potential effects in primary care settings using the double diamond co-design process and the Medical Research Council (MRC) Framework for Developing and Evaluating Complex Interventions.

Methods: The study will be conducted in two phases. In phase I, …

Healthcare Professionals’ Experiences And Perspectives On Self-Management Education For Breast Cancer Survivors In Australian Primary Care: A Qualitative Study, Meng Yuan Li, Tao Wang, Daniel Terry, Haiying Wang, Isabella Zhao, Jing Yu Tan

Research outputs 2022 to 2026

Purpose: Breast cancer has been recognised as a chronic condition, with survivors experiencing long-term physical and psychosocial effects following treatment. Supporting breast cancer survivors to self-manage their health can optimise health-related quality of life and reduce symptom burden. Self-management education (SME) has been advocated at the policy and programme level in Australian primary care, but its uptake is often limited. This study explores healthcare professionals’ (HCPs) experiences and perceptions of SME in primary care, aiming to identify factors influencing its implementation and to support survivorship care for breast cancer survivors in Australia.

Methods: A qualitative descriptive approach was adopted involving …

Rhetorical Physics And The Laws Of Language: A Comparative Analysis Of President Trump And President Macron At The United Nations 2025, David Edmund Allen

Research outputs 2022 to 2026

The paper features a textual analysis of the UN speeches made by the US President Donald Trump and by France’s President Macron. President Trump’s speech was made in the absence of a teleprompter and lasted almost an hour. President Macron’s speech was representative of a more standard diplomatic speech. Both speeches are analyzed using a variety of models and techniques. The analysis incorporates an exploration of Manin’s link of Zipf’s law to concepts from information theory and algorithmic complexity, Tao’s concepts applied to power laws, ‘E pluribus unum’, out of many, one, plus a completely new application of Villermaux’s universal …

Urinary Sodium, Table Salt Use And Incidence Of Late-Onset Asthma In Females And Males: Evidence From A Large Prospective Cohort, Selma Kronsteiner-Gicevic, Alysha S. Thompson, Martina Gaggl, Aedín Cassidy, Nicola P. Bondonno, Charmaine J.M. Lim, Robab Breyer-Kohansal, Tilman Kühn

Research outputs 2022 to 2026

Background: The contribution of dietary sodium to asthma development remains unclear, particularly for adult-onset disease. We examined associations between estimated 24-h urinary sodium excretion, table salt use and incident asthma in a large prospective cohort.

Methods: We analysed 420 041 adults aged 40–69 years without prior asthma. Incident asthma was ascertained through linked health records. Urinary sodium was estimated using the INTERSALT equation from spot urine samples. Frequency of adding salt at the table was self-reported. Associations were evaluated using multivariable Cox proportional hazards models with adjustment for sociodemographic, lifestyle and clinical factors.

Results: Over a median 10.9-year follow-up, 11 …

Genome-Wide Cline Analysis Identifies New Locus Contributing To A Barrier To Gene Flow Across An Antirrhinum Hybrid Zone, David L. Field, Sean Stankowski, Taylor Reiter, Jitka Polechova, Desmond Bradley, Daniel M. Richardson, Annabel Whibley, Arka Pal, Daria Shipilina, Louis Boell, Melinda Pickup, Yongbiao Xue, Enrico Coen, Nicholas Barton

Research outputs 2022 to 2026

Identification of the genomic regions that contribute to reproductive isolation and how they interact is a major goal of evolutionary genetics. Much effort has focused on locating candidate genes and potential barrier loci by scanning genomes for regions of excess differentiation (FST). An alternative, and perhaps more robust approach, is to scan for genomic regions exhibiting steep clines in allele frequency across a hybrid zone. We develop a computationally efficient method for approximating cline parameters for large number of loci, and apply it to genomic data from across a hybrid zone between flower colour varieties of Antirrhinum majus (A. m. …

Cognitive Decline In Dutch-Type Hereditary And Sporadic Cerebral Amyloid Angiopathy: A 5-Year Follow-Up Study, Rosemarie Van Dort, Vera C.J. Van Stek-Smits, Sanne E. Schriemer, Reinier G.J. Van Der Zwet, Manon R. Schipper, Sabine Voigt, Ellen P. Hart, Vandhana Easwaran, Hamid R. Sohrabi, Kevin Taddei, Samantha L. Gardener, Ralph N. Martins, Steven M. Greenberg, Matthias J.P. Van Osch, Marianne A.A. Van Walderveen, Marieke J.H. Wermer, Ellis S. Van Etten

Research outputs 2022 to 2026

Introduction: Cerebral amyloid angiopathy (CAA) is associated with cognitive impairment, but its longitudinal course of cognitive decline remains unclear. We investigated domain-specific cognitive trajectories in Dutch-type hereditary (D-CAA) and sporadic CAA (sCAA) to compare patterns and rates of decline. Methods: We included 181 participants – 93 D-CAA mutation carriers (59 without, 34 with prior intracerebral hemorrhage [ICH]) and 88 with sCAA (57 without, 31 with ICH) – who underwent annual neuropsychological assessment. Longitudinal change in global cognition, memory, processing speed, and executive function was analyzed using linear mixed models. Results: Over 5 years, cognitive decline was subtle but measurable. Memory …

Does Poor Regulation Lead To Pollution? Key Takeaways From A Systematic Review, Vincent Emenyonu, Kat O. Mara, Mark Lund

Research outputs 2022 to 2026

Formal recycling of used lead acid batteries (ULAB) is a multibillion-dollar industry, valued at US$12.12 billion in 2024, and expected to grow to more than $26 billion within eight years. Demand for recycled lead (Pb) for new batteries grows in developing countries where costs limit the uptake of lithium-ion batteries. ULAB recycling in these regions poses significant danger to human health and the environment. Stringent regulatory approaches for ULAB recycling in developing countries, intended to reduce pollution, have thus far been ineffective as they typically do not adequately cover small-scale informal recycling in rural and remote communities. We examine what …

More Than Just Fair: Legitimizing Ai Through Reciprocity, Ethical Ai Characteristics And Personal Information Sharing, Shahid Hussain, Asim Qazi, Violetta Wilk

Research outputs 2022 to 2026

This research examines how perceived reciprocity and perceived ethical AI characteristics – fairness, accountability, and transparency (FAT principles) – shape consumers’ willingness to share personal information and its downstream consequences in AI-mediated consumer-brand interactions. Grounded in social exchange theory, we conceptualize personal information sharing as a behavioral gateway through which ethical exchange cues translate into perceived algorithmic legitimacy and intention to co-create value. Using a two-study design, consisting of a scenario-based experiment (n = 184) and a cross-sectional survey (n = 612), the findings of this research show that reciprocity and FAT principles robustly increase willingness to share personal information. …

Undercooked Or Over Easy? Perceptions Of Initial Teacher Educators On The Growth Of Alternative Authority To Teach Contracts, Sharon A. Louth, Linda Mahony

Australian Journal of Teacher Education

The practice of employing pre-service teachers (PST) in schools prior to the completion of their teacher training, has grown over the last three years as the teacher shortage across Australia and the world worsens. This study examines the perceived impact of Alternative Authority to Teach (AAT) contracts on the teaching profession through the lens of university lecturers working within the Initial Teacher Education (ITE) space. This phenomenological research sought to gain a wider understanding of the impact of AAT contracts on ITE stakeholders and their PST. Qualitative semi-structured interviews were conducted with eleven university lecturers. A thematic analysis of the …

Peripheral Nerve Sensory Fibers Are Recruited With Less Current And Greater Selectivity By Conventional Waveforms Compared With High-Frequency Waveforms, Janie Provencher, Harrison T. Finn, Janet L. Taylor, Simon C. Gandevia, Jane E. Butler, Martin E. Héroux

Research outputs 2022 to 2026

Transcutaneous spinal stimulation aims to target dorsal spinal roots, which deliver sensory information to the spinal cord. However, the stimulation waveform that most effectively recruits sensory fibers at the lowest intensity has not been identified. The purpose of this study was to compare conventional and high-frequency burst-modulated stimulation waveforms in their ability to recruit sensory fibers, as assessed by H-reflex threshold, recruitment characteristics, and motor fiber activation. In participants with intact neurological function (n ¼ 12), soleus H-reflex recruitment curves were recorded for 10 stimulation waveforms: a conventional waveform (400 μs), serving as the reference condition, high-frequency burst-modulated waveforms (2, …

Impact Of Capillary Imbibition On Development Of Unconventional Oilfields: A Five-Year Review, Yihang Xiao, You, Yongming He, Han Xu, Lei Wang, Yujie Yuan

Research outputs 2022 to 2026

The imbibition process, which is characterized by the displacement of non-wetting phase by wetting phase in porous media, plays a crucial role in enhancing oil recovery of unconventional reservoirs. However, due to the complex nature of reservoir characteristics and fluid properties, existing research on this phenomenon presents contradictory conclusions and interpretations. This paper aims to fill this knowledge gap by providing a comprehensive review of the fundamental concepts, primary mechanical factors, and critical influences in oil-water imbibition. Primary mechanisms, including capillary, viscous, gravitational, hydrostatic, inertial, capillary back, dead end, and osmotic forces, are analyzed in terms of their key roles …

Story, Mapping And “Jarriny”: A Collaborative Exploration Of Artistic Responses To Extreme Weather In The Work Of Natalie Davey And The 2023 Fitzroy River Floods, Natalie Davey, Renée Newman

Research outputs 2022 to 2026

Extreme weather events caused by human created climate change not only cause catastrophic impact on human and the more-than-human populations but can also trigger permanent changes to place. With these changes, stories shift, in turn influencing knowledge and cultural systems. This article is a dialogue between Natalie Davey and Renée Newman, about the role of art, story, mapping and “jarriny” (translating to totem) as a tool for education on extreme weather events and climate crisis. We also consider the vital role custodianship plays in response to and recovery from an extreme weather event, as was the case for Natalie Davey …

The Moderating Effect Of Dietary Fiber And Protein On The Relationship Between Symptoms Of Depression And Anxiety And Cognitive Decline, Samantha L. Gardener, Hilal Salim Said Al Shamsi, Stephanie R. Rainey-Smith, Hamid R. Sohrabi, Kevin Taddei, Colin L. Masters, Ralph N. Martins, W. M.A.D. Binosha Fernando

Research outputs 2022 to 2026

Introduction: Depression and anxiety often co-occur with Alzheimer's disease, exacerbating the associated cognitive impairment. This study examined moderating effects of dietary protein and fiber intake on relationships between depressive and anxiety symptoms, and cognitive decline.

Methods: Cognitively unimpaired (n = 553; 39.4% male, 70.6 ± 9.6 years) provided baseline fiber and protein intake, and had repeated cognitive testing and symptoms of depression/anxiety measured (baseline and up to eight follow-ups over 144 months). Moderation and simple slope analyses were employed in the cohort as a whole and following stratification by sex.

Results: Fiber intake moderated the relationship between change in depressive …

The Poly-Arginine Peptide R18d Inhibits Amyloid-Beta (Aβ) Aggregation And Aβ-Induced Cytotoxicity, Reduces Intracellular Tau Aggregation, And Exhibits Oral Bioavailability, Vaishali Bagda, Zainab H. Farooz, Neville W. Knuckey, Samantha M. South, Stuart K. Gribble, Maitri Tomar, Prashant Bharadwaj, Ajish Ariyath, Kevin Taddei, Ralph N. Martins, Bruno P. Meloni

Research outputs 2022 to 2026

Background/Objectives: Effective disease-modifying therapies targeting pathogenic proteins associated with Alzheimer’s disease (AD) remain limited. This study investigated the therapeutic potential of the neuroprotective, cationic arginine-rich peptide R18D to mitigate the pathogenic effects of amyloid-beta (Aβ) and tau associated with AD.

Methods: R18D was examined for its ability to inhibit Aβ aggregation in a cell-free assay, attenuate Aβ-induced cytotoxicity in MC65 cells, and suppress intracellular tau aggregation in two neural cell models. Intracellular tau aggregation was quantified using a homogeneous time-resolved fluorescence assay. Additionally, a pilot pharmacokinetic study of R18D was conducted in mice following oral gavage administration.

Results: In the …

Waste Material Utilization In Civil Engineering Applications: Advances, Challenges, And Future Directions—A Scoping Review, Chathurika Dassanayake, Nuha S. Mashaan, Ridmi Galagedara

Research outputs 2022 to 2026

This PRISMA-guided scoping review examines the use of waste materials in civil engineering as a sustainable approach to reducing environmental impacts, conserving natural resources, and supporting circular economy principles. The rapid growth of urbanization, industrialization, mining, and agricultural activities generates large amounts of waste materials, including fly ash, ground granulated blast-furnace slag, bauxite residue, mining tailings, waste rock, acid-mine drainage sludge, waste plastics, post-consumer vulcanized rubber, recycled construction materials, and agricultural ashes. The disposal of these materials often creates serious environmental and land-use problems, making their reuse increasingly important. In this context, civil engineering is one of the most promising …

Weathering In-Beyond Hydro(S)Cenes, Bronwyn Bailey-Charteris, Kathryn Mcmahon, Mary Christina Rapp, Natalie Davey

Research outputs 2022 to 2026

This paper examines the cultural, ecological and political dimensions of the contemporary water crisis through a curatorial and environmental humanities lens. Through the watery conceptual epoch of the Hydrocene, it highlights the work of artists and interdisciplinary practitioners whose hydro-Artistic methods propose ways to realign human-water relations. Central to this analysis is the role of curatorial care, here understood as a practice of convening, holding and enabling reciprocal encounters between bodies of water, artists and communities. Bringing these diverse practices into dialogue, the paper proposes water not only as subject matter but as a potential collaborator and leaky agent. It …

Why Are Western Australian Girls Less Motivated Than Boys To Study Senior Secondary Higher-Level Mathematics Courses? Relationships Between Gender, Prior Achievement, And Mathematics Course Aspirations, Jane Kirkham, Elaine Chapman

Research outputs 2022 to 2026

Secondary school students, and particularly girls, may avoid enrolling in higher-level mathematics courses despite having the competence to succeed in these courses. Understanding the reasons behind these choices is essential to addressing this concern. In this study, the teachers of Western Australian Year 10 students (n=886) nominated the mathematics course in which they believed each participating student could succeed in Year 11 with participants grouped into four achievement cohorts on this basis. Then each teacher course nomination was compared to participants’ own course selection with participants classified as either aspiring below or at/above their judged potential achievement level. We then …

The Effects Of Anti-Parkinsonian Medications On Bone Mineral Density: A Systematic Review, Mícheál Ó Breasail, Motaz B. El-Leissy, Karan P. Singh, Matthew Smith, Jakub Mesinovic, Marc Sim, Andrew Evans, David Blacker, Saman Heshmat, Neil Mahant, Christian Girgis, Peter R. Ebeling, Ayse Zengin

Research outputs 2022 to 2026

IntroductionParkinson's disease (PD) is associated with elevated fracture risk, particularly at the hip. Antiparkinsonian medications have also been associated with increased fracture risk; although their direct effects on bone mineral density (BMD) remains unclear.ObjectiveInvestigate whether antiparkinsonian medications influence BMD.MethodsA systematic search of four databases (Embase, MEDLINE, APA PsycINFO, Web of Science) was conducted up to 24/11/2025 using terms related to PD, antiparkinsonian medications and bone.ResultsA total of 748 records were identified, with 543 screened following deduplication. Fourteen studies underwent full-text review, of which seven met inclusion criteria. Three studies assessed bone mineral content or surrogate measures at non-standard sites (hand …

Dimpled Surfaces For Thermal Performance Enhancement In Solar Collectors, Furqan Jamil, Baig, Amna Adil, Aasia Farrukh

Research outputs 2022 to 2026

With escalating environmental concerns, solar energy is a feasible approach to support a sustainable environment, considering the pressing need to move away from fossil fuels. Optimizing solar collector’s efficiency improves energy capture and lowers carbon emissions. One innovative technique is to the surface of solar collectors. The heat transfer is greatly increased by adding such tiny indentations, encouraging turbulence in the incoming working fluid. The article reviews the effect of dimples on the efficiency of various collector applications, including flat plate collector, solar water heaters, solar air collectors, parabolic trough solar collectors, photovoltaic thermal systems, desalination, and many others. The …

The Impact Of Hypertensive Disorders Of Pregnancy On Cognitive Outcomes In Offspring: Systematic Review And Meta-Analysis, Berihun Dachew, Tusa, Getinet Ayano, Kim Betts, Amanuel Gebremedhin, Daniel Rudaizky, Gizachew A. Tessema, Rosa Alati

Research outputs 2022 to 2026

Purpose To synthesis the available research on the association between hypertensive disorders during pregnancy (HDP) and adverse cognitive outcomes in children. Methods PubMed, MEDLINE, Embase, Scopus, CINAHL, and PsycInfo were searched from inception to February 2026 to identify relevant studies. Effect estimates and 95% confidence intervals (CIs) were extracted and pooled using inverse variance–weighted random-effects meta-analysis. Results Thirty-nine observational studies published between 1982 and 2026, covering over 12.5 million mother-offspring pairs, were included in the final analysis. The findings indicate that HDP were associated with a 39% increased risk of Intellectual Disability (ID) (OR = 1.39, 95% CI = 1.30–1.47) …

Effect Of Anisotropic Hydraulic Conductivity On Groundwater Seepage Into A Rectangular Tunnel In Submerged Sand, Deki Yangzom Ghaley, Sanjay Kumar Shukla

Research outputs 2022 to 2026

Managing groundwater seepage around tunnels is critical to tunnel design, particularly when the tunnel is constructed below the water table. Accurate seepage flow patterns and water inflow prediction under ordinary and critical conditions are imperative to mitigate potential tunnel construction and service disasters. In the past, an in-depth study on the anisotropic hydraulic conductivity of the soil mass that may affect the seepage condition has not been carried out. In this work, this aspect has been investigated numerically for a rectangular tunnel submerged within a homogeneous sand mass, considering the anisotropic hydraulic conductivity ratio (kz / kx, kz = vertical …

Advancing Dimensional Models Of Psychopathology In Cancer: Insights From Applying The Hierarchical Taxonomy Of Psychopathology (Hitop), Darren Haywood, Jai Carmichael, Miriam K. Forbes, Roman Kotov, Robert F. Krueger, Aidan G.C. Wright, Susan L. Rossell, David Castle, Wendy Lam, Maryam Lustberg, Colin E. Vize, Anna Ugalde, Phyllis Butow, Nicolas H. Hart

Research outputs 2022 to 2026

Objective: Cancer survivors, defined as those living with or beyond a cancer diagnosis, experience more than double the prevalence of psychopathology when compared to the general population. Categorical diagnostic systems, such as the Diagnostic and Statistical Manual of Mental Disorders (DSM), remain dominant in psycho-oncology despite concerns about reliability, validity, and clinical utility for this population. Dimensional frameworks, such as the Hierarchical Taxonomy of Psychopathology (HiTOP), offer a more precise alternative; however, they have not yet been widely applied in cancer survivors. Accordingly, the objective of this research was to examine the applicability of HiTOP to cancer survivors. Methods: Data …

Artificial Intelligence Based Predictive Simulation And Decision-Support Framework For Full Scale Wastewater Treatment Systems, Muhammad Hassnain, Cameron Veal, Sarada M.W. Lee, Muhammad Rizwan Azhar

Research outputs 2022 to 2026

Full scale wastewater treatment plants (WWTPs) generate extensive sensor and laboratory datasets that remain challenging to translate into real-time operational insight, while increasing hydraulic variability, energy constraints, tightening effluent regulations, and events such as sensor faults, hydraulic shocks, and effluent-quality excursions require predictive decision-support tools beyond conventional mechanistic modelling. This study presents a full-scale, industry-deployed artificial intelligence (AI) framework integrating machine learning (ML), simulation, and operational boundary definition across a nitrogen-removal WWTP in Australia. Up to nine years of high-frequency online instrumentation data (≤419,000 records per target; 5–30 min resolution) and ~3000 laboratory samples were used to train and evaluate …