Digital Commons Network^™

Healthcare Professionals’ Experiences And Perspectives On Self-Management Education For Breast Cancer Survivors In Australian Primary Care: A Qualitative Study, Meng Yuan Li, Tao Wang, Daniel Terry, Haiying Wang, Isabella Zhao, Jing Yu Tan

Research outputs 2022 to 2026

Purpose: Breast cancer has been recognised as a chronic condition, with survivors experiencing long-term physical and psychosocial effects following treatment. Supporting breast cancer survivors to self-manage their health can optimise health-related quality of life and reduce symptom burden. Self-management education (SME) has been advocated at the policy and programme level in Australian primary care, but its uptake is often limited. This study explores healthcare professionals’ (HCPs) experiences and perceptions of SME in primary care, aiming to identify factors influencing its implementation and to support survivorship care for breast cancer survivors in Australia.

Methods: A qualitative descriptive approach was adopted involving …

Introducing Contested Weather: Art And The Power Of Collaborative Response In Times Of Crisis, Jo Pollitt, Helena Grehan

Research outputs 2022 to 2026

No abstract provided.

Muscle–Tumor Crosstalk In Exercise Oncology: Exercise-Induced Myokines And Cancer Cachexia, Amirhossein Ahmadi Hekmatikar, Francesco Bettariga, Álvaro López Llorente, Diego Fernández-Lázaro, Katsuhiko Suzuki, D. Maryama Awang Daud

Research outputs 2022 to 2026

Exercise-induced myokines, such as IL-6, irisin, and myostatin, play crucial roles in mediating systemic adaptations and modulating tumor progression. This narrative review synthesizes evidence on how regular moderate-intensity exercise affects the myokine network within the tumor microenvironment (TME) of solid tumors. Results from the 86 included studies indicate that structured training (aerobic: 45–65% VO2 max; resistance: 45–70% 1RM) enhances the expression of beneficial myokines that support immune surveillance, reduce inflammation, and improve muscle–tumor cross-talk. IL-6 demonstrates a dual modulatory effect on inflammation and immunity; irisin contributes to tumor apoptosis, while myostatin downregulation supports muscle integrity and metabolic balance. Evidence suggests …

Peripheral Nerve Sensory Fibers Are Recruited With Less Current And Greater Selectivity By Conventional Waveforms Compared With High-Frequency Waveforms, Janie Provencher, Harrison T. Finn, Janet L. Taylor, Simon C. Gandevia, Jane E. Butler, Martin E. Héroux

Research outputs 2022 to 2026

Transcutaneous spinal stimulation aims to target dorsal spinal roots, which deliver sensory information to the spinal cord. However, the stimulation waveform that most effectively recruits sensory fibers at the lowest intensity has not been identified. The purpose of this study was to compare conventional and high-frequency burst-modulated stimulation waveforms in their ability to recruit sensory fibers, as assessed by H-reflex threshold, recruitment characteristics, and motor fiber activation. In participants with intact neurological function (n ¼ 12), soleus H-reflex recruitment curves were recorded for 10 stimulation waveforms: a conventional waveform (400 μs), serving as the reference condition, high-frequency burst-modulated waveforms (2, …

Rhetorical Physics And The Laws Of Language: A Comparative Analysis Of President Trump And President Macron At The United Nations 2025, David Edmund Allen

Research outputs 2022 to 2026

The paper features a textual analysis of the UN speeches made by the US President Donald Trump and by France’s President Macron. President Trump’s speech was made in the absence of a teleprompter and lasted almost an hour. President Macron’s speech was representative of a more standard diplomatic speech. Both speeches are analyzed using a variety of models and techniques. The analysis incorporates an exploration of Manin’s link of Zipf’s law to concepts from information theory and algorithmic complexity, Tao’s concepts applied to power laws, ‘E pluribus unum’, out of many, one, plus a completely new application of Villermaux’s universal …

Story, Mapping And “Jarriny”: A Collaborative Exploration Of Artistic Responses To Extreme Weather In The Work Of Natalie Davey And The 2023 Fitzroy River Floods, Natalie Davey, Renée Newman

Research outputs 2022 to 2026

Extreme weather events caused by human created climate change not only cause catastrophic impact on human and the more-than-human populations but can also trigger permanent changes to place. With these changes, stories shift, in turn influencing knowledge and cultural systems. This article is a dialogue between Natalie Davey and Renée Newman, about the role of art, story, mapping and “jarriny” (translating to totem) as a tool for education on extreme weather events and climate crisis. We also consider the vital role custodianship plays in response to and recovery from an extreme weather event, as was the case for Natalie Davey …

The Moderating Effect Of Dietary Fiber And Protein On The Relationship Between Symptoms Of Depression And Anxiety And Cognitive Decline, Samantha L. Gardener, Hilal Salim Said Al Shamsi, Stephanie R. Rainey-Smith, Hamid R. Sohrabi, Kevin Taddei, Colin L. Masters, Ralph N. Martins, W. M.A.D. Binosha Fernando

Research outputs 2022 to 2026

Introduction: Depression and anxiety often co-occur with Alzheimer's disease, exacerbating the associated cognitive impairment. This study examined moderating effects of dietary protein and fiber intake on relationships between depressive and anxiety symptoms, and cognitive decline.

Methods: Cognitively unimpaired (n = 553; 39.4% male, 70.6 ± 9.6 years) provided baseline fiber and protein intake, and had repeated cognitive testing and symptoms of depression/anxiety measured (baseline and up to eight follow-ups over 144 months). Moderation and simple slope analyses were employed in the cohort as a whole and following stratification by sex.

Results: Fiber intake moderated the relationship between change in depressive …

The Poly-Arginine Peptide R18d Inhibits Amyloid-Beta (Aβ) Aggregation And Aβ-Induced Cytotoxicity, Reduces Intracellular Tau Aggregation, And Exhibits Oral Bioavailability, Vaishali Bagda, Zainab H. Farooz, Neville W. Knuckey, Samantha M. South, Stuart K. Gribble, Maitri Tomar, Prashant Bharadwaj, Ajish Ariyath, Kevin Taddei, Ralph N. Martins, Bruno P. Meloni

Research outputs 2022 to 2026

Background/Objectives: Effective disease-modifying therapies targeting pathogenic proteins associated with Alzheimer’s disease (AD) remain limited. This study investigated the therapeutic potential of the neuroprotective, cationic arginine-rich peptide R18D to mitigate the pathogenic effects of amyloid-beta (Aβ) and tau associated with AD.

Methods: R18D was examined for its ability to inhibit Aβ aggregation in a cell-free assay, attenuate Aβ-induced cytotoxicity in MC65 cells, and suppress intracellular tau aggregation in two neural cell models. Intracellular tau aggregation was quantified using a homogeneous time-resolved fluorescence assay. Additionally, a pilot pharmacokinetic study of R18D was conducted in mice following oral gavage administration.

Results: In the …

Urinary Sodium, Table Salt Use And Incidence Of Late-Onset Asthma In Females And Males: Evidence From A Large Prospective Cohort, Selma Kronsteiner-Gicevic, Alysha S. Thompson, Martina Gaggl, Aedín Cassidy, Nicola P. Bondonno, Charmaine J.M. Lim, Robab Breyer-Kohansal, Tilman Kühn

Research outputs 2022 to 2026

Background: The contribution of dietary sodium to asthma development remains unclear, particularly for adult-onset disease. We examined associations between estimated 24-h urinary sodium excretion, table salt use and incident asthma in a large prospective cohort.

Methods: We analysed 420 041 adults aged 40–69 years without prior asthma. Incident asthma was ascertained through linked health records. Urinary sodium was estimated using the INTERSALT equation from spot urine samples. Frequency of adding salt at the table was self-reported. Associations were evaluated using multivariable Cox proportional hazards models with adjustment for sociodemographic, lifestyle and clinical factors.

Results: Over a median 10.9-year follow-up, 11 …

Waste Material Utilization In Civil Engineering Applications: Advances, Challenges, And Future Directions—A Scoping Review, Chathurika Dassanayake, Nuha S. Mashaan, Ridmi Galagedara

Research outputs 2022 to 2026

This PRISMA-guided scoping review examines the use of waste materials in civil engineering as a sustainable approach to reducing environmental impacts, conserving natural resources, and supporting circular economy principles. The rapid growth of urbanization, industrialization, mining, and agricultural activities generates large amounts of waste materials, including fly ash, ground granulated blast-furnace slag, bauxite residue, mining tailings, waste rock, acid-mine drainage sludge, waste plastics, post-consumer vulcanized rubber, recycled construction materials, and agricultural ashes. The disposal of these materials often creates serious environmental and land-use problems, making their reuse increasingly important. In this context, civil engineering is one of the most promising …

Weathering In-Beyond Hydro(S)Cenes, Bronwyn Bailey-Charteris, Kathryn Mcmahon, Mary Christina Rapp, Natalie Davey

Research outputs 2022 to 2026

This paper examines the cultural, ecological and political dimensions of the contemporary water crisis through a curatorial and environmental humanities lens. Through the watery conceptual epoch of the Hydrocene, it highlights the work of artists and interdisciplinary practitioners whose hydro-Artistic methods propose ways to realign human-water relations. Central to this analysis is the role of curatorial care, here understood as a practice of convening, holding and enabling reciprocal encounters between bodies of water, artists and communities. Bringing these diverse practices into dialogue, the paper proposes water not only as subject matter but as a potential collaborator and leaky agent. It …

Why Are Western Australian Girls Less Motivated Than Boys To Study Senior Secondary Higher-Level Mathematics Courses? Relationships Between Gender, Prior Achievement, And Mathematics Course Aspirations, Jane Kirkham, Elaine Chapman

Research outputs 2022 to 2026

Secondary school students, and particularly girls, may avoid enrolling in higher-level mathematics courses despite having the competence to succeed in these courses. Understanding the reasons behind these choices is essential to addressing this concern. In this study, the teachers of Western Australian Year 10 students (n=886) nominated the mathematics course in which they believed each participating student could succeed in Year 11 with participants grouped into four achievement cohorts on this basis. Then each teacher course nomination was compared to participants’ own course selection with participants classified as either aspiring below or at/above their judged potential achievement level. We then …

A Scalable Workflow Using Digital Cognitive Assessment And Ptau217 For Mci Detection, Srinivasan Vairavan, Nicholas Griffin, David Wilson, Gallen Triana-Baltzer, Victoria Brugada-Ramentol, Elena Vera-Campuzano, Daniel Alcolea, Silvia Fallone, Lucy Mackintosh, Lindsey Mette, James D. Doecke, Joanne Robertson, Larry Ward, Gonzalo Sánchez Benavides, Carolina Minguillon, Clàudia Porta Mas, Adrià Tort-Merino, Mircea Balasa, Oriol Grau Rivera, Marc Suárez Calvet, Lewis Taylor, Íñigo Rodríguez-Baz, Javier Arranz, Juan Fortea, Ioannis Tarnanas, Marc Jones, Gayle Wittenberg, Emmanuel Streel, Maria Florencia Iulita

Research outputs 2022 to 2026

Introduction: Blood biomarkers like phosphorylated tau (p-tau)217 offer high diagnostic accuracy for Alzheimer's disease (AD) but face implementation challenges in low-prevalence settings. We evaluated the Altoida NeuroMarker Platform as a digital cognitive triage tool before plasma p-tau217 testing.

Methods: XGBoost models were trained to predict mild cognitive impairment (MCI) and p-tau217 status in 688 individuals across Australia, Spain, and the United States using the Altoida NeuroMarker. p-tau217 status was dichotomized using a threshold of 0.04 pg/mL (LucentAD). We modeled a two-step workflow (Altoida, plasma p-tau217) to enrich downstream biomarker testing, assuming 30% prevalence of AD pathology.

Results: The Altoida NeuroMarker …

Analysis Of Normalization, Resampling, And Weighted Voting To Improve K-Nn Performance In Diabetes Disease Detection, Agustiyar, R. Rizal Isnanto, Budi Warsito, Adi Wibowo, Ferry Jie

Research outputs 2022 to 2026

Diabetes is a global health issue, and machine learning has become crucial for early detection. The k-Nearest Neighbors (k-NN) machine learning algorithm is widely used because it is simple and easy to implement; however, its performance is sensitive to feature scale differences, class imbalance, and the assumption of uniform decision-making, as commonly found in clinical datasets such as the Pima Indians Diabetes (PID) dataset. Many studies have been conducted to address these issues; however, very few have systematically evaluated the combined effects of preprocessing and distance-based decision-making methods on k-NN performance. This study evaluates the combined effects of preprocessing strategies …

Review And Development Of An Explicit Machine Learning Model For Pollutant Gas Solubility In Ionic Liquids As Green Solvents, Amir Dashti, Farid Amirkhani, Mojtaba Raji, John L. Zhou, Ali Altaee, Ali Braytee, Brett Turner, Hossein Ali Khonakdar, Amir Razmjou

Research outputs 2022 to 2026

The increasing release of greenhouse gases (GHGs) like CO₂, CH₄, N₂O, and industrial contaminants (indirect GHGs) such as SO₂ and H₂S has prompted significant global worries due to their role in climate change, air pollution, and harm to the environment. Ionic liquids (ILs) as green solvents have emerged as promising alternatives to traditional solvents because of their minimal volatility, high thermal stability, and adjustable physicochemical characteristics. Yet, limited gas solubility data in ILs is hindering their applications in carbon capture and air pollution control. Machine learning (ML) is a powerful tool for modeling and simulating the solubility of polluting gases …

Effectiveness Of Lay Workers Delivering Behavioural Activation For People With Depression: Systematic Review And Meta-Analysis, Shwikar Othman, Lauren Blekkenhorst, Asangaedem Akpan, Irene Ngune, Nilufeur Mckay, Alison Kennedy, Elizabeth Armstrong, Michael Hunter, Kevin Murray, Mathew Coleman, Richard Gray, Emma Jones, Christopher Lee, Martin Jones

Research outputs 2022 to 2026

Background Behavioural activation is effective for depression, but its effectiveness in treating adults with depression when delivered by lay workers remains unclear. Aims To examine the effectiveness of behavioural activation delivered by lay workers, compared with any control group, in reducing depressive symptoms in adults. Method This systematic review searched six databases from inception to January 2025, for randomised controlled trials (RCTs) comparing behavioural activation and any control conditions for individuals with depression when delivered by lay workers. Additional searches were conducted in the international trial registries and reference lists (PROSPERO registration CRD42024625620). Risk of bias was assessed using the …

Does Set Configuration Influence Long-Term Adaptations To Complex Training In National-Level Wrestlers? A Volumematched Randomized Trial, Yueqiang Ma, Pengpeng Gou, Yuxiong Huang, Jialiang Yu, Lijia Zhou, Kai Xu, Binbin Jia, Danyang Li

Research outputs 2022 to 2026

Objectives: Complex training is commonly used to enhance strength and explosive performance in athletes; however, the long-term influence of set configuration within complex training remains unclear in highly trained wrestlers. This randomized, volumematched trial investigated whether set configuration influences long-term adaptations to complex training (CT) in national-level male Chinese-style wrestlers. Specifically, the study compared the effects of cluster-set complex training (CS-CT) and traditional-set complex training (TS-CT) on maximal strength, lower-limb explosive performance, anaerobic power, and sport-specific performance.

Methods: Sixteen highly trained wrestlers (Tier 3; n=16) completed an 8-week lowerbody CT program performed twice weekly. Participants were randomly allocated to either …

Corporate Eldercare Responsibility: Forging A Strategic Approach To Sustaining Work–Care Balance, Kazunori Kobayashi, Gabriel Eweje, Mayowa Babalola, Tazeeb Rajwani

Research outputs 2022 to 2026

Purpose – Population ageing is intensifying pressures on employees with eldercare responsibilities, yet eldercare remains weakly addressed within corporate social responsibility (CSR) and business strategy research. This study aims to examine how firms strategically respond to these emerging pressures and develops the concept of corporate eldercare responsibility. Design/methodology/approach – The study draws on qualitative interviews with senior managers in large Japanese corporations. The analysis focuses on how firms interpret eldercare-related challenges and translate them into organisational responses within existing employment and CSR strategy frameworks. Findings – The findings identify two distinct CSR logics shaping organisational responses. Provision-focused practices extend supports …

Bridging The Gender Gap In Ghanaian Local Governance: Key Enablers And Pathways, Martin Brantuo, Victor Fannam Nunfam, Joseph Akanganngang Asitik, Ebenezer Afrifa-Yamoah

Research outputs 2022 to 2026

This qualitative study examines factors facilitating women’s election to District Assemblies in Ghana through social capital and supply–demand theoretical frameworks. Through interviews with thirteen female Assembly members and four officials, the research identifies four critical enablers: financial resources, political affiliations, community relationships, and educational qualifications. Financial resources emerged as crucial for campaign management and voter mobilization, while political party support provided strategic advantages despite the nonpartisan nature of local elections. Strong interpersonal relationships within communities proved vital for building voter trust, and educational background enhanced candidates’ credibility. The findings inform recommendations for implementing gender quotas, establishing campaign funding mechanisms, voter …

An International Multidisciplinary Consensus Statement On Laparoscopic Liver Biopsy, Si Yi Lei, Yu Han, Don C. Rockey, Khalid Alswat, Vincent Wai Sun Wong, Nozim Jumaev, Carlos Jesus Toro-Huamanchumo, Safwan Taha, Mohamed El-Kassas, Jacob George, Mark Muthiah, Omar Ghanem, Masato Yoneda, Dao Viet Hang, Giada Sebastiani, George Papatheodoridis, Adam Abu-Abeid, Andrew G. Robertson, Sang Hyun Kim, Rudolf Weiner, Kamal Mahawar, Asim Shabbir, Mohammad Kermansaravi, Reynu Rajan, Yosuke Seki, Halit Eren Taskin, Scott Shikora, Edward Oliveros, Chetan Parmar, Qiuye Cheng, Omar Thaher, Elena Ruiz-Úcar, Rodolfo Oviedo, Rui Ribeiro, Mario Musella, Almino C. Ramos, Seung-Wan Ryu, Tamer Abdelbaki, Wei Jei Lee, Man Pan Chan, Jose Eduardo Garcia Flores, James Skinovsky, Ahmad Madkhali, Sylvia Weiner, Frank Tacke, Wah Yang, James Neuberger, Ming-Hua Zheng

Research outputs 2022 to 2026

Laparoscopic liver biopsy (LLB) provides a way to obtain liver tissue samples under direct visual inspection of the liver surface. It complements percutaneous liver biopsy (PLB) for complex or high-risk cases where PLB cannot be performed. Clinical practices for LLB vary across centers due to the lack of international standards. To improve the procedural quality and diagnostic efficiency of LLB, a multidisciplinary panel of 45 international experts from 6 continents, including hepatology, hepatobiliary surgery, gastrointestinal surgery, and metabolic and bariatric surgery, developed this consensus statement through three rounds of a modified Delphi process. This consensus covers clinical application scenarios, high-risk …

Using Social Return On Investment To Evaluate Services That Support The Health Of People Experiencing Homelessness In Australia: A Scoping Review, Cate Mckenna, Christopher Rouen, Mary O'Loughlin

Research outputs 2022 to 2026

The increasing demand for homelessness services in Australia highlights the need for robust evaluation methodologies to assess their social impact. Traditional economic evaluation methods often struggle to capture the intangible social and health outcomes associated with homelessness. Social return on investment (SROI), an outcomes-based framework driven by stakeholders, offers a flexible and comprehensive approach to measuring social, economic and environmental impacts. This scoping review examines the application of SROI in evaluating services that support the health of people experiencing or at risk of homelessness in Australia. A total of 25 reports from grey literature (2010-2023) were reviewed. The findings reveal …

Where To Now With Privacy? A Systematic Literature Review With Human–Artificial Intelligence Synthesis (Slr-Hais), Moulik M. Zaveri, Ameet Pandit, Violetta Wilk, Steven D’Alessandro

Research outputs 2022 to 2026

Purpose – The development of digital technologies has led to changes in how consumers perceive privacy. This systematic literature review (SLR) aims to introduce human–artificial intelligence (AI) synthesis (HAIS) as a novel methodology for extending traditional SLRs. Design/methodology/approach – A comprehensive review of the privacy literature is conducted to demonstrate the efficacy of the SLR with HAIS (SLR-HAIS) approach, using 149 articles published by top marketing journals on consumer privacy. The PRISMA approach is adopted as the organizing framework. In addition, the TCCM framework is applied in conjunction with Leximancer-driven HAIS analysis, which utilizes natural language processing techinques for thematic …

Proteomic Evidence Indicates Ultrasound-Assisted Extraction Enhances Recovery Of Membrane-Associated Proteins In Hericium Erinaceus, Tanvir Ahmed, Angéla Juhász, Utpal Bose, Netsanet Shiferaw Terefe, Michelle L. Colgrave

Research outputs 2022 to 2026

Membrane-associated fungal proteins mediate essential functions and contain bioactive proteins with therapeutic potential but are underrepresented in aqueous extracts due to hydrophobicity and lipid associations. Ultrasound-assisted aqueous extraction was applied to Lion’s mane (Hericium erinaceus), and the proteins were fractionated by molecular weight (≥30 kDa, 10–30 kDa, 3–10 kDa). Proteomic profiling using data-dependent (DDA) and data-independent (DIA) mass spectrometry identified 1500 and 1702 proteins, respectively (1% global FDR). Ultrasonication induced surface irregularity and a less compact, heterogeneous microstructure. Topology predictions showed higher proportions of transmembrane and secretory proteins in ultrasonicated fractions. Extraction preserved protein integrity (82% molecular-weight retention, 97% tryptic …

Implementation Of Co-Designed Strategies Enhances Referral To Pulmonary Rehabilitation For People With Copd In Tertiary Care: An Interrupted Time Series Study, Sarah Hug, Vinicius Cavalheri, Daniel F. Gucciardi, Richard Norman, Christine Teague, Natasha Bear, Kylie Hill, Optimal Consortium

Research outputs 2022 to 2026

Background: Pulmonary rehabilitation programs (PRPs) are a core component of care for people with chronic obstructive pulmonary disease (COPD), yet referral is low. The aims of this study were to; (i) engage with people with COPD receiving care at a tertiary hospital and HCPs involved in the management of people with COPD, to co-design and implement strategies that sought to improve referrals to PRPs; (ii) evaluate the effect of implementing co-designed strategies on the rate of referral to PRPs across three tertiary hospitals; and (iii) understand the sustainability of co-designed strategies by estimating relative costs and number of potentially prevented …

Norm Dust Intake: Comparison Of Personal Air Sampling And Bioassays, Gregory S. Hewson, Martin I. Ralph, Marcus Cattani

Research outputs 2022 to 2026

Intake of naturally occurring radioactive materials (NORM), particularly the inhalation of thorium-bearing dust in mineral sand operations, has traditionally been assessed via personal air sampling (PAS). However, data from bioassay studies suggest that the actual intake determined via PAS may be underestimated. This review integrates thorium intake estimates derived from historical bioassay datasets, such as urine, faeces, lung counting, and thoron-in-breath tests, with historical PAS data. The findings indicated that bioassay-based predictions of intake were consistently greater, with mean bioassay-to-PAS intake ratios ranging from 2.6 to 4.2. The contributing factors to this discrepancy include biokinetic model uncertainties, potential dust sampler …

Patterns Of Language And Visuospatial Lateralisation In Three-Year-Old Children, Josephine E. Quin-Conroy, Donna M. Bayliss, Stephanie J. Bovell, Debra Eamer, Georgina H.M. Earl, Simon E. Fisher, Clyde Francks, Murray T. Maybery, Sarah Pillar, Desiree Silva, Andrew J.O. Whitehouse, Nicholas A. Badcock

Research outputs 2022 to 2026

Little is known about how or when language and visuospatial processing lateralise in the brain, and if individual differences in lateralisation are related to early language or visuospatial abilities. We explored if patterns of language and visuospatial lateralisation are related to cognitive skills in young children. A large sample of 3-year-olds (n = 136) attempted two functional transcranial Doppler ultrasound (fTCD) tasks to estimate language and visuospatial lateralisation. At the group level, language was lateralised to the left hemisphere, but visuospatial processing was weakly lateralised to the right hemisphere. The relationship between patterns of lateralisation and cognitive skills was investigated …

The Effect Of Boosting Dietary Lactobacillus And Phytochemical Rich Foods On Biomarkers Of Longevity—A Phase Ii Randomised Placebo Controlled Trial, Robert J. Thomas, Madeleine Williams, Jeffrey W.F. Aldous, Stacey A. Kenfield, Robert U. Newton

Research outputs 2022 to 2026

As men age, systemic inflammation increases, whereas grip strength (GS) and testosterone levels tend to fall. This rate of decline is known to be influenced by gut microbial health, lifestyle and diet but the role for interventions to slow this decline are less well established. This double-blind randomised controlled trial evaluated the impact, and explored the synergistic potential, of boosting phytochemical rich foods and Lactobacillus probiotics on these physical and biological markers. Two hundred and eight men with untreated early prostate cancer managed with observation only (average age 74 years) received a phytochemical rich supplement (PRS) containing concentrated broccoli, green …

The Life Study: A Cross-Sectional Study Protocol For Lifestyle Risk Factors For Chronic Disease Across The Stages Of Reproductive Ageing, Laura E. Pernoud, Jamie L. Noll, Paul A. Gardiner, Melinda Dean, Kathryn M. Broadhouse, Meegan Anne Walker, Hattie H. Wright, Anthony Villani, Joseph Scott, Alexandra P. Metse, Mia A. Schaumberg

Research outputs 2022 to 2026

Introduction: The dynamic physiological and hormonal changes through the menopause transition predispose women to an increased risk of chronic diseases including cardiovascular disease, metabolic disease, depression and dementia. The underlying mechanisms remain unclear, yet it is thought that chronic systemic inflammation and changes to lifestyle behaviours play important roles. The LIfestyle risk Factors for chronic disease across the stagEs of reproductive ageing (LIFE study) is a cross-sectional study aimed to characterise how hormonal and lifestyle (physical activity, diet and sleep) differences across pre, peri and postmenopause influence chronic systemic inflammation, visceral adiposity, cognitive function and sleep health. Methods and analysis: …

Impacts Of The Early Collaborative Intervention On Mother-Preterm Infant Interaction At One Month Of Age: Secondary Analysis Of A Randomized Controlled Trial, Charlotte Sahlén Helmer, Ulrika Birberg Thornberg, Thomas Abrahamsson, Evalotte Mörelius

Research outputs 2022 to 2026

Background A sensitive, well-functioning maternal interaction is vital for healthy infant development. For moderate to late preterm infants, this is even more important as this group of infants are at increased risk of facing neurodevelopmental disorders. The Early Collaborative Intervention supports parent-preterm infant interaction and includes three sessions, two in the hospital and one after discharge. Objective To investigate the impact of the Early Collaborative Intervention, compared with standard care, on mother-preterm infant interaction at one month corrected age. Design A longitudinal randomized controlled trial, reporting secondary outcomes from the first follow-up. Setting The intervention was conducted at a pediatric …

Multiple-Nozzle Sprays: Comparison To Single-Nozzle Sprays And Role Of Directional Conditional Filtering, Farzad Hossain, Matthew J. Cleary, Yasir M. Al-Abdeli, Mehdi Khiadani

Research outputs 2022 to 2026

Spray-based droplet evaporation systems used in desalination and cooling applications depend on both nozzle arrangement and the interpretation of measured droplet behaviour. This study examines (i) how multi-nozzle configurations differ from single-nozzle characteristics and (ii) how ensemble-averaged measurements change when droplets are separated according to their motion direction (upward or downward). Atmospheric water sprays generated by full-cone spray nozzles were investigated using Particle Image Velocimetry (PIV) for droplet axial velocity measurements and Shadowgraph imaging to determine droplet size and count. Directional filtering was performed using Large Eddy Simulation (LES), validated against experiments. Single- and dual-nozzle configurations were tested with horizontal …