Digital Commons Network^™

The Tiger Vol. 111 Issue 14 2017-04-24, Clemson University

Tiger Newspapers 2017

No abstract provided.

Clemson Trustees Minutes, 2017 April 21, Clemson University Board Of Trustees

Minutes

No abstract provided.

The Tiger Vol. 111 Issue 13 2017-04-17, Clemson University

Tiger Newspapers 2017

No abstract provided.

The Tiger Vol. 111 Issue 12 2017-04-10, Clemson University

Tiger Newspapers 2017

No abstract provided.

12th Annual Focus On Creative Inquiry Poster Forum Program, Clemson University

Focus on Creative Inquiry

The 2017 Focus on Creative Inquiry Poster Forum displays a selection of the projects accomplished by Clemson University students in their Creative Inquiry teams.

What is Creative Inquiry? It is small-group learning for all students, in all disciplines. It is the imaginative combination of engaged learning and undergraduate research – and it is unique to Clemson University.

In Creative Inquiry, small teams of undergraduate students work with faculty mentors to take on problems that spring from their own curiosity, a professor’s challenge, or the pressing needs of the world around them. Students take ownership of their projects. They ask questions, …

The Tiger Vol. 111 Issue 11 2017-04-03, Clemson University

Tiger Newspapers 2017

No abstract provided.

Correlated Mutation In The Evolution Of Catalysis In Uracil Dna Glycosylase Superfamily, Bo Xia, Yinling Liu, Jose Guevara, Jing Li, Celeste Jilich, Ye Yang, Liangjiang Wang, Brian N. Dominy, Weiguo Cao

Publications

Enzymes in Uracil DNA glycosylase (UDG) superfamily are essential for the removal of uracil. Family 4 UDGa is a robust uracil DNA glycosylase that only acts on double-stranded and single-stranded uracil-containing DNA. Based on mutational, kinetic and modeling analyses, a catalytic mechanism involving leaving group stabilization by H155 in motif 2 and water coordination by N89 in motif 3 is proposed. Mutual Information analysis identifies a complexed correlated mutation network including a strong correlation in the EG doublet in motif 1 of family 4 UDGa and in the QD doublet in motif 1 of family 1 UNG. Conversion of EG …

And Then There Were Four, Maggie Mason Smith

Publications

No abstract provided.

Correlated Mutation In The Evolution Of Catalysis In Uracil Dna Glycosylase Superfamily, Bo Xia, Yingling Liu, Jose Guevara, Jing Li, Celeste Jilich, Ye Yang, Liangjiang Wang, Brian N. Dominy, Weiguo Cao

Publications

Enzymes in Uracil DNA glycosylase (UDG) superfamily are essential for the removal of uracil. Family 4 UDGa is a robust uracil DNA glycosylase that only acts on double-stranded and single-stranded uracil-containing DNA. Based on mutational, kinetic and modeling analyses, a catalytic mechanism involving leaving group stabilization by H155 in motif 2 and water coordination by N89 in motif 3 is proposed. Mutual Information analysis identifies a complexed correlated mutation network including a strong correlation in the EG doublet in motif 1 of family 4 UDGa and in the QD doublet in motif 1 of family 1 UNG. Conversion of EG …

Integrating Multimodal Arguments Into High School Writing Instruction, Emily Howell, Tracy Butler, David Reinking

Publications

We conducted a formative experiment investigating how an intervention that engaged students in constructing multimodal arguments could be integrated into high school English instruction to improve students’ argumentative writing. The intervention entailed three essential components: (a) construction of arguments defined as claims, evidence, and warrants; (b) digital tools that enabled the construction of multimodal arguments; and (c) a process approach to writing. The intervention was implemented for 11 weeks in high school English classrooms. Data included classroom observations; interviews with the teacher, students, and administrators; student reflections; and the products students created. These data, analyzed using grounded-theory coding and constant-comparison …

Adulting 101 Virtual Display, Maggie Mason Smith

Presentations

No abstract provided.

Holocaust Remembrance Display, Maggie Mason Smith

Presentations

In remembrance of the 1943 Warsaw Ghetto Uprising a display of materials focused on the Holocaust has been set up on the 4th floor of Cooper Library. The display contains a range of items but is centered on Nazi-era ghettos, concentration camps and their liberation, Holocaust-centered art and literature, and memoirs of Holocaust survivors. The display will be up throughout the month of April and all items are available for checkout.

The Tiger Vol. 111 Issue 10 2017-03-27, Clemson University

Tiger Newspapers 2017

No abstract provided.

March 2017 Full Issue

NASIG Newsletter

No abstract provided.

The Tiger Vol. 111 Issue 9 2017-03-13, Clemson University

Tiger Newspapers 2017

No abstract provided.

The Tiger Vol. 111 Issue 8 2017-03-06, Clemson University

Tiger Newspapers 2017

No abstract provided.

Corporate Public Relations Dynamics: Internal Vs. External Stakeholders And The Role Of The Practitioner, Lea Anna Cardwell, Sean Williams, Andrew Pyle

Publications

Most public relations research advocates for stronger organization-public relationships and the implementation of dialogic theory to advance the practice and elevate the status of the public relations practitioner. However, this study reveals that internal relationship dynamics can prevent corporate public relations practitioners from carrying out this function of the public relations role. Twelve weeks of observation and eleven interviews were conducted at a Fortune 1000 technology company to gain insights on how corporate PR practitioners build relationships with external publics, to gauge practitioners’ orientation to dialogue, and to identify challenges to external relationship building. Results show that internal relationship management …

Give Me A K-I-L-L, Maggie Mason Smith

Publications

No abstract provided.

Cues To Cervical Cancer Screening Among U.S.-Hispanic Women, Arelis Moore De Peralta, Bonnie Holaday, Ida Mikisa Hadoto

Publications

Introduction: Hispanic women’s cervical cancer rates are disproportionately high. Cues to cervical cancer screening (Cues to Action) are strategies to activate the decision-making process to get screened for cervical cancer. This study used the health belief model to examine which cues prompt Hispanic women to undergo cervical cancer screening and how perceptions could be potentiated by cues to cervical cancer screening.

Method: A cross-sectional survey was conducted among Hispanic women 18 to 65 years old (n = 220). Generalized linear modeling was used.

Results: Spanish media and reminders by mother and doctors were relevant cues. Generalized linear modeling showed …

Fabrication Challenges And Perspectives On The Use Of Carbon-Electrode Dielectrophoresis In Sample Preparation, Rodrigo Martinez-Duarte

Publications

The focus of this review is to assess the current status of three-dimensional (3D) carbon-electrode dielectrophoresis (carbonDEP) and identify the challenges currently preventing it from its use in high-throughput applications such as sample preparation for diagnostics. The use of 3D electrodes over more traditional planar ones is emphasised here as a way to increase the throughput of DEP devices. Glass-like carbon electrodes are derived through the carbonisation of photoresist structures made using photolithography. These biocompatible carbon electrodes are not ideal electrical conductors but are more electrochemically stable than noble metals such as gold and platinum. They are also significantly less …

Contribution Of Engineered Nanomaterials Physicochemical Properties To Mast Cell Degranulation, Monica M. Johnson, Ryan Mendoza, Achyut J. Raghavendra, Ramakrishna Podila, Jared M. Brown

Publications

The rapid development of engineered nanomaterials (ENMs) has grown dramatically in the last decade, with increased use in consumer products, industrial materials, and nanomedicines. However, due to increased manufacturing, there is concern that human and environmental exposures may lead to adverse immune outcomes. Mast cells, central to the innate immune response, are one of the earliest sensors of environmental insult and have been shown to play a role in ENM-mediated immune responses. Our laboratory previously determined that mast cells are activated via a non-FcεRI mediated response following silver nanoparticle (Ag NP) exposure, which was dependent upon key physicochemical properties. Using …

Charge-Transfer Interactions Induce Surface Dependent Conformational Changes In Apolipoprotein Biocorona, Achyut J. Raghavendra, Nasser Alsaleh, Jared M. Brown, Ramakrishna Podila

Publications

Upon introduction into a biological system, engineered nanomaterials (ENMs) rapidly associate with a variety of biomolecules such as proteins and lipids to form a biocorona. The presence of “biocorona” influences nano–bio interactions considerably, and could ultimately result in altered biological responses. Apolipoprotein A-I (ApoA-I), the major constituent of high-density lipoprotein (HDL), is one of the most prevalent proteins found in ENM-biocorona irrespective of ENM nature, size, and shape. Given the importance of ApoA-I in HDL and cholesterol transport, it is necessary to understand the mechanisms of ApoA-I adsorption and the associated structural changes for assessing consequences of ENM exposure. Here, …

Microfoundations Of Organizational Paradox: The Problem Is How We Think About The Problem, Ella Miron-Spektor, Amy Ingram, Josh Keller, Wendy K. Smith, Marianne W. Lewis

Publications

Competing tensions and demands pervade our work lives. Accumulating research examines organizational and leadership approaches to leveraging these tensions. But what about individuals within firms? Although early paradox theory built upon micro-level insights from psychology and philosophy to understand the nature and management of varied competing demands, corresponding empirical studies are rare, offering scarce insights into why some individuals thrive with tensions while others struggle. In response, we contribute to the microfoundations of organizational paradox with a theoretical model and robust measures that help unpack individuals' varied approaches to tensions. Following rigorous scale development in Study 1, including samples from …

Corporate Public Relations Dynamics: Internal Vs. External Stakeholders And The Role Of The Practitioner, Lee Anna Cardwell, Sean Williams, Andrew S. Pyle

Publications

Most public relations research advocates for stronger organization-public relationships and the implementation of dialogic theory to advance the practice and elevate the status of the public relations practitioner. However, this study reveals that internal relationship dynamics can prevent corporate public relations practitioners from carrying out this function of the public relations role. Twelve weeks of observation and eleven interviews were conducted at a Fortune 1000 technology company to gain insights on how corporate PR practitioners build relationships with external publics, to gauge practitioners’ orientation to dialogue, and to identify challenges to external relationship building. Results show that internal relationship management …

Invisibility Through The Interface: The Social Consequences Of Spatial Search, Jordan Frith

Publications

Location-based services are mobile applications that use a device’s location to provide relevant results. Spatial search applications are a popular subset of location-based services that enable people to search through their surrounding space to find nearby locations. This article examines spatial search applications through a framework that combines critical geography research with research on the power search engines exert over information visibility. The main argument of the article is that popular spatial search applications, such as Yelp, may subtly reproduce existing forms of spatial segregation by rendering certain location invisible through the mobile mapping interface.

Smug2 Dna Glycosylase From Pedobacter Heparinus As A New Subfamily In Udg Superfamily, Panjiao Pang, Ye Yang, Jing Li, Zhong Wang, Weiguo Cao, Wei Xie

Publications

Base deamination is a common type of DNA damage that occurs in all organisms. DNA repair mechanisms are essential to maintain genome integrity, in which the base excision repair (BER) pathway plays a major role in the removal of base damage. In the BER pathway, the uracil DNA glycosylase superfamily is responsible for excising the deaminated bases from DNA and generates apurinic/apyrimidinic (AP) sites. Using bioinformatics tools, we identified a family 3 SMUG1-like DNA glycoyslase from Pedobacter heparinus (named Phe SMUG2), which displays catalytic activities towards DNA containing uracil or hypoxanthine/xanthine. Phylogenetic analyses show that SMUG2 enzymes are closely related …

High Order Algebraic Splitting For Magnetohydrodynamics Simulation, Mine Akbas, Muhammad Mohebujjaman, Leo G. Rebholz, Mengying Xiao

Publications

This paper proposes, analyzes and tests high order algebraic splitting methods for magnetohydrodynamic (MHD) flows. The main idea is to apply, at each time step, Yosida-type algebraic splitting to a block saddle point problem that arises from a particular incremental formulation of MHD. By doing so, we dramatically reduce the complexity of the nonsymmetric block Schur complement by decoupling it into two Stokes-type Schur complements, each of which is symmetric positive definite and also is the same at each time step. We prove the splitting is O(Δt³) accurate, and if used together with (block-)pressure correction, is fourth order. …

Profile Of April Hathcock, Christian Burris

NASIG Newsletter

No abstract provided.

The Tiger Vol. 111 Issue 7 2017-02-27, Clemson University

Tiger Newspapers 2017

No abstract provided.

The Tiger Vol. 111 Issue 6 2017-02-20, Clemson University

Tiger Newspapers 2017

No abstract provided.