Digital Commons Network^™

Polymersomes As Chemotherapeutic Agents For Non-Invasive Treatment Of Glioblastoma, Tj Fletcher, Molli Garifo, Jessica Larsen, Jessica Larsen

Chemistry Summer Research Program

No abstract provided.

Accessing Rare Heterocycles From Alkynyl Ethers And Nitrogenous Electrophiles & The Development Of Small Molecule Inhibitors Against Naegleria Fowleri Infection, James W. D. Morris, Samuel Kwain, Daniel C. Whitehead

Chemistry Summer Research Program

No abstract provided.

Combining Alginate Beads With Methylene To Create A Biosensor To Assess The Quality Of Milk, Vivien Zheng, Barbara Guinati, Carlos D. Garcia

Chemistry Summer Research Program

No abstract provided.

Multi-Catalysis: Trifluoromethylation Of Amides, Ethan Apsley, Jason Wilt, Giovani Gutierrez, Byoungmoo Kim

Chemistry Summer Research Program

No abstract provided.

Cryogrinding And Physical Analysis Of A Thermoplastic Polyurethane Elastomer, Timothy E. Whitesell, Marcia Reeves, David L. Helm, Joseph S. Thrasher

Chemistry Summer Research Program

No abstract provided.

Stimuli-Responsive Self-Folding Bilayer Polymer Thin Films, Astrid Garcia, Dimuthu Edirisinghe, Bogdan Oliy, George Chumanov

Chemistry Summer Research Program

No abstract provided.

Tuning Oxo Formation Energies Using Spectator Ligands In The Mil-100 Metal Organic Framework, Victoria E. Lee, Stephen P. Vicchio, Rachel B. Getman

Chemistry Summer Research Program

No abstract provided.

Effects Of Low-Energy X-Rays And Uv Radiation On Fibroblast Cells, Michelle Gorodisky, Congyue Peng, Arianna Csiszer, Delphine Dean

Chemistry Summer Research Program

No abstract provided.

Dynamics Of Ionizable Polymers In Ionic Liquid (Il) Using Nuclear Magnetic Resonance Spectroscopy, Sophie Ntipouna, Hayden Sasko, Shalika D. K. Meedin, Dvora Perahia

Chemistry Summer Research Program

No abstract provided.

Halogen Bonding In Nitrogen And Iodine Compounds To Form Novel Cocrystals, Dahlia Griffin, Ann Jiang, Colin D. Mcmillen, William T. Pennington

Chemistry Summer Research Program

No abstract provided.

Predicting Corrosion Damage In The Human Body Using Artificial Intelligence: In Vitro Progress And Future Applications Applications, Michael A. Kurtz, Ruoyu Yang, Mohan S. R. Elapolu, Audrey C. Wessinger, William Nelson, Kazzandra Alaniz, Rahul Rai, Jeremy L. Gilbert

Publications

Artificial intelligence (AI) is used in the clinic to improve patient care. While the successes illustrate the impact AI can have, few studies have led to improved clinical outcomes. A gap in translational studies, beginning at the basic science level, exists. In this review, we focus on how AI models implemented in non-orthopedic fields of corrosion science may apply to the study of orthopedic alloys. We first define and introduce fundamental AI concepts and models, as well as physiologically relevant corrosion damage modes. We then systematically review the corrosion/AI literature. Finally, we identify several AI models that may be Preprint …

An Introduction To Consumptive Use Of Water In South Carolina, Heather Bergerud Nix, Mani Rouhi Rad

Journal of South Carolina Water Resources

Effective water resource management requires understanding the supply of and the demand for water. In South Carolina, as in other places, water demand is often determined using total withdrawal volumes. However, the volume of water that is withdrawn can be significantly different from the volume that is actually consumed, which becomes unavailable for downstream uses. Water used for energy generation is commonly excluded from evaluations of total withdrawal volume because it is often assumed to be no or low consumptive use, meaning much of the withdrawn water is returned to the source and remains available for downstream uses. Additionally, energy …

Chlorophyll A Predictions In A Piedmont Lake In Upstate South Carolina Using Machine-Learning Approaches, Ibrahim O. Busari, Debabrata Sahoo, Raghavendra Jana, Charles Privette

Journal of South Carolina Water Resources

Freshwater systems are often breeding grounds for harmful algal blooms (HABs), although they are more dominant in ponds and lakes due to the prevailing conditions in those bodies of water. Therefore, the monitoring, modeling, and management of HABs requires knowledge of the complex interrelationship between factors that influence HABs and their detrimental effect on the ecosystem. High concentrations of chlorophyll a are often used to measure algal blooms in bodies of water. Generally, water samples are collected from the field and the concentration of chlorophyll a is measured in a laboratory and compared to water quality standards in order to …

Full Issue - Volume 9, Issue 1

Journal of South Carolina Water Resources

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Hyflex Pedagogy: Six Strategies Supported By Design-Based Research, Emily Howell, Koti Lee Hubbard, Sandra Linder, Stephanie M. Madison, Joseph Ryan, William C. Bridges

Publications

Purpose–This study investigates the following research question: What pedagogical strategies are necessary for the success of the project? The findings to this question are based in new media literacies and help to further pedagogy in an emerging HyFlex model while also grounding in needed theorization.

Design/methodology/approach–This study uses design-based research(DBR) across two iterations and four doctoral, higher education courses, using mixed methods of data collection and analysis.

Findings–Six pedagogical strategies influential for HyFlex research are presented, each grounded in a new media literacy skill.

Originality/value–These six pedagogical strategies help practitioners grappling with the HyFlex or blended learning model merge traditional …

Thermoplastics Foams: An Automotive Perspective, Sai Aditya Pradeep, Srishti Shukla, Nathaniel Brown, Srikanth Pilla

Publications

The automotive industry has witnessed a massive shift in terms of materials used, ranging from being a metallic heavyweight in the 1950s to employing a hybrid sandwich of multiple material systems. This apparent shift can be attributed to achieving improvements in performance, safety and fuel efficiency, along with responding to the various environmental regulations imposed by different governments. The recent advocacy of Corporate Average Fuel Economy (CAFE) standard of 54.5 MPG by 2025 by the US Environmental Protection Agency (EPA) to reduce greenhouse gas (GHG) emissions [1] has spurred the sector at large towards the use of lightweight materials.

On The Measurement Of Nakazima Testing Based Out-Of-Plane Forming Limit Curves Using 2d Digital Image Correlation, Akshat Agha, Fadi Abu-Farha

Publications

The strain compensation method for measuring in-plane forming limit curves (FLCs) using 2D digital image correlation developed previously [A method of measuring in-plane forming limit curves using 2D Digital Image Correlation, SAE Int. J. Mater. Manf., 2023] was modified and extended to more versatile and popular out-of-plane FLCs. The current study introduces a straightforward strain compensation technique for measuring Nakazima testing based out-of-plane FLCs utilizing an affordable single-camera (2D) DIC system. In this study, forming tests are performed on two automotive-grade sheet metal alloys: DP980 steel and a 6xxx series aluminum alloy using the Nakazima test method. The experiments are …

“That Means Nothing To Me As A Normal Person Who Doesn't Know About Patents”: Usability Testing Of Google Patents And Patent Public Search With Undergraduate Engineering Students, Graham Sherriff, Molly Rogers

Journal of the Patent and Trademark Resource Center Association

Patent searching is an important research tool for undergraduate engineering students, yet it requires special topic knowledge to conduct successfully. Patent database websites have the ability to alleviate or add to the complexity of patent searching, depending on their usability. Prompted by the launch of the US Patent and Trademark Office’s Patent Public Search (PPS) website in early 2022, the authors investigated the usability of PPS and Google Patents. The study's objective was to gain insights into the ways in which the websites of commonly-used patent databases support undergraduate students’ patent searching activities. The study examined students’ performance of typical …

Lessons Learned From Incorporating Climate Considerations In The Three Rivers Watershed-Based Plan, Gregory Carbone, Jory Fleming, Kathryn Ellis, Guillermo J. Espinosa

Journal of South Carolina Water Resources

The South Carolina Department of Health and Environmental Control has recently incentivized planners to incorporate climate change projections into watershed-based plans. Methods for doing so vary by geography, specific basin-level conditions, and available resources. This short communication documents an early example developed by a collaborative team including a council of governments, private contractor, and university researchers. We outline steps taken to construct climate change scenarios, incorporate them into a basin-level model, and develop a holistic approach to climate adaptation and resilience for the Three Rivers Watershed-Based Plan in the Columbia, South Carolina, metropolitan area. We present lessons learned about integrating …

Mapping And Characterization Of Center Pivot And Lateral Move Irrigation Systems In South Carolina Using Quantum Geographic Information System, Udayakumar Sekaran, José O. Payero

Journal of South Carolina Water Resources

In recent decades, the adoption of overhead irrigation systems, especially center pivots, to irrigate row crops has been steadily increasing in South Carolina. The adoption of irrigation in the state has been enhanced by the predominance of coarse-textured soils with low water-holding capacities, which increases the likelihood of obtaining a significant and profitable crop yield response to irrigation. As the number of overhead irrigation systems in the state increases, it is vital to understand their number, location, and characteristics for better planning and managing available water resources. The objective of this project was to map and characterize the overhead irrigation …

Relative Sea Level Rise In The Winyah Bay-Waccamaw River Tidal System Over The Last Thirteen Years, Thomas M. Williams, Thomas L. O'Halloran

Journal of South Carolina Water Resources

Prediction of sea level rise (SLR) in response to climate change has been the focus of worldwide research, most focusing on the impact by human development. The research has been limited to estuaries and tidal rivers near harbors dealing with the hydrodynamics of reversing tidal flows. This article focuses on the Waccamaw River National Wildlife Refuge in coastal South Carolina where freshwater unidirectional flow is common. We examined the record of water levels in the Waccamaw and Pee Dee Rivers over the period 2007–2019 and the length of record of the United States Geographical Survey (USGS) gauge at Pawleys Island …

Evaluating The Ability Of Constructed Intertidal Eastern Oyster (Crassostrea Virginica) Reefs To Address Shoreline Erosion In South Carolina, Peter R. Kingsley-Smith, Andrew W. Tweel, Sharleen P. Johnson, Gary W. Sundin, Michael S. Hodges, Benjamin W. Stone, Gregory D. Sorg, Denise M. Sanger

Journal of South Carolina Water Resources

The application of nature-based solutions to address shoreline erosion and the loss of salt marsh in coastal South Carolina has centered around the creation of intertidal oyster (Crassostrea virginica) reefs that act as natural breakwaters. The installation of such living shoreline materials often results in a rapid accumulation of fine sediments, followed by wild oyster recruitment to suitable materials, and then more gradually the growth of salt marshes (primarily Spartina alterniflora). Leveraging more than two decades of oyster reef restoration and living shorelines research at the South Carolina Department of Natural Resources, this study quantitatively assessed performance rates for both …

Clemson Commencement Program, May 2023, Clemson University

Clemson Commencement Programs

No abstract provided.

Clemson University Women Trailblazers, A. M. Alexander, J. W. Harris

Clemson University Women Trailblazers

No abstract provided.

Long-Time Stability For An Imex Discretization Of The 1d Fujita Equation, Victoria Luongo

Honors College Theses

We study an efficient time-stepping scheme for the 1D Fujita equation that is implicit for the linear terms but explicit for the nonlinear terms. We analyze the long-time stability of the scheme for varying parameter values, which reveal parameter value regimes in which the method is stable. We provide numerical results that illustrate the theory and show the analytically derived stability conditions are sufficient to achieve long-time stability results.

Differences In Crowding And Stress Experienced By Emergency Medicine Physicians Prior To And During The Covid-19 Pandemic, Caroline Grace Barrows

Honors College Theses

Burnout in Emergency Medicine physicians has become an increasingly apparent problem in the United States. This psychological syndrome is a result of emotional exhaustion, detachment, and an overwhelming sense of ineffectiveness (Maslach & Leiter, 2016). Work demands within the emergency department are likely to produce chronic exposure to stressors. However, the onset of the COVID-19 pandemic likely contributed to amplifying workplace stressors, suggesting that the rate at which burnout developed was elevated. In the present study, data were collected from Emergency Medicine physicians at Greenville Memorial Hospital in Greenville, South Carolina prior to the start of and during the COVID-19 …

Optical Sensing Of Capillary Waves, Matthew Franklin Reid

Honors College Theses

I relay various topics I learned about this semester and summarize the specialties of Clemson’s Micro-Photonics Laboratory. I report pertinent information for characterizing capillary waves with lasers and one recent method of characterizing them. Lastly, I outline a potential plan for mathematically modeling a laser’s reflection off of capillary waves, and potential plans moving forward.

Exploration Of Collaborative Design Spaces: Engineering Interactions And Workflows In Product Development, Frederick Rowell

Honors College Theses

Product Lifecycle Management (PLM) initiatives can improve an enterprise’s efficiency by increasing collaborative design opportunities within its business structure. PLM solutions provide digital mediums to collaborate on all aspects of a company’s workflow, including engineering, testing, manufacturing, marketing, business, and field support services. This paper examines the major PLM tools and software used to establish a collaborative engineering design space; computer-aided design (CAD), computer-aided engineering (CAE), computer-aided manufacturing (CAM), and product data management (PDM). The interactions between these PLM tools and a design team’s organizational structure are analyzed to determine some of the most effective PLM integration strategies to improve …

Characterizing Metabolic Activity Of Fish Liver Microsomes Towards Fluoxetine In Four Fish Species Using Michaelis-Menten Enzyme Kinetics, Morgan Steiner

Honors College Theses

Discharge of pharmaceuticals into the environment is of emergent concern due to the unknown long-term effects on aquatic organisms. Wastewater treatment plants are not effective in completely removing pharmaceuticals, allowing them to be discharged into aquatic systems. To investigate the potential effects of fluoxetine, a common antidepressant, on aquatic species, the potential of four freshwater fish species to metabolize this drug was investigated. Livers from redbreast sunfish, bluegill, striped jumprock and bluehead chub were collected, homogenized, and centrifuged to collect the microsomes. These microsomes were used in an assay to determine the in vitro hepatic metabolism of fluoxetine by cytochrome …

Music Mentor, Jacob Webb

Honors College Theses

Extra-curricular learning is on the rise, and many are interested in expanding their current knowledge by utilizing the recent increase in educational technology. While many forms of educational technology exist, there are few interactive and engaging platforms that teach music theory. Apps such as Perfect Ear and MyMusicTheory are great for becoming familiar with reading music and recognizing pitches, however, they often become dry with repetition and repeated tasks. By combining existing technologies that can complete real time conversions from raw audio to MIDI, our goal was to gather information such as harmonies, key and compatible chords from the user’s …