Expandable Tissue Engineered Living Pulmonary Heart Valve For Pediatric Patients, David Podolsky

All Theses

Cardiovascular disease is an extremely deadly disease that affects people throughout the world. It is the leading cause of death worldwide, affecting over a quarter of the population.1 Some forms of cardiovascular disease directly affect the heart valves and their function. Surgery or a replacement device are the most common current treatment options. These treatments are effective in addressing heart valve diseases in adults, but they are less effective when used for children patients. This creates a need to develop a solution for the child population.

Congenital heart defects are structural abnormalities that often lead to infant mortality.2,3 Pulmonary valves, …

Optimizing Park Locations While Considering Resident Behavior, Lu Liu

All Theses

Urban parks and green-spaces significantly enhance community well-being by improving physical health, mental wellness, and environmental quality. Given these extensive benefits, ensuring fair and widespread access to urban parks represents a critical priority in urban planning. Despite the advantages of parks, optimizing their location poses unique and complex challenges distinct from traditional facility location problems, such as those involving emergency services or schools. The core distinction arises from the decentralized nature of residents’ park selection behaviors. Unlike centralized allocations typically managed by public administrators, park usage decisions are driven by individual preferences and behaviors. This decentralized decision-making introduces two additional …

The Uses Of Dramaturgical Research In Cinematic Storytelling, Asset Design, And Adaptation In Animation, Delaney L. Walker

All Theses

“The Black Hair” is a creative project that explores the convergence of cinematic adaptation, dramaturgical research, and animation design in retelling a traditional Japanese short folktale from the Heian Era. Rooted in the practice of theatrical dramaturgy, this thesis advocates for a research-driven creative pipeline by developing a culturally respectful and historically grounded approach to developing cinematic storyboards. By thoroughly examining the chronicles of history and the sociocultural context, the project seeks to foster deeper cultural appreciation while reintroducing a lesser-known narrative to modern audiences through a visual medium. The project draws stylistic and narrative inspiration from iconic Japanese filmmakers …

Exploring Promising Practices In Temporary Informal Education Programs For Visitor And Community Engagement In The United States National Park Service, Cameron L. Miller

All Theses

According to the National Association for Interpretation (NAI), interpretation is “a purposeful approach to communication that facilitates meaningful, relevant, and inclusive experiences that deepen understanding, broaden perspectives, and inspire engagement with the world around us” (NAI, 2021). Interpretation is an integral part of a visitor’s experience to informal education venues like museums, zoos, aquariums, and parks and is at the heart of experience planning within the National Park Service (NPS). However, traditional interpretation methods, such as formal interpretation programs, tend to engage a small percentage of overall park visitors, that are typically older and white. Recognizing the need for interpretation …

Effect Of Amino Acid Derivatives And Polyphenol Supplementation On Skeletal Muscle Growth In-Vitro And In-Vivo, Gabriella C. Iheanacho

All Theses

Background

Satellite cells (SCs) are myogenic precursor cells that play a crucial role in muscle growth, and their activity can be influenced by nutrient supplementation. Muscle growth can also be stimulated using growth-promoting hormones; however, there are no approved growth hormones for use in sheep in the United States (Qaid & Abdoun, 2022). This limitation highlights a need to identify alternative compounds that would serve as nutrient supplements to enhance muscle growth and thereby improve meat production. Amino acid derivatives such as guanidinoacetic acid (GAA) and 5-hydroxytryptophan (5-HTP), along with the polyphenol quercetin, are naturally derived compounds that have shown …

Post-Harvest Storage Of Fuzzy Cottonseed: Quality, Airflow Modeling, And Energy Use, Elijah T. Porter

All Theses

Fuzzy cottonseed is a valuable byproduct of the cotton ginning process. When cottonseed exits the cotton gin, it often retains high temperatures and moisture contents. Once in a storage facility, the cottonseed needs to be conditioned for safe storage. The overall objectives of this study were to analyze quality changes in cottonseed according to storage conditions, determine the airflow resistance properties of fuzzy cottonseed, develop a computational fluid dynamics (CFD) model of a representative cottonseed storage facility, and analyze cottonseed aeration fan strategies, runtimes, and costs. Changes in quality dictate the allowable storage time for cottonseed and are impacted by …

The Development And Application Of A Method To Simulate Commotio Cordis Inducing Impacts For The Evaluation Of Football Chest Protective Equipment, Bianca J. Henline

All Theses

As one of the most widely played and watched contact sports in the United States, football presents a significant risk of blunt chest trauma. Thus, effective chest protection is essential to prevent rare but fatal injuries like commotio cordis. Despite this, current test methods for certifying chest protective equipment fail to account for injury metrics relevant to commotio cordis events. Recent literature identifies rib deformation and viscous criterion as critical predictors of commotio cordis, yet these metrics are not adequately addressed in the existing testing standard. Furthermore, this standard exclusively assesses chest gear specific to baseball and lacrosse through projectile …

Polyphenols For The Mitigation Of Vascular Calcification; In Vitro And In Vivo Studies, Abdullah Altuhami

All Theses

Globally, cardiovascular diseases, in most cases associated with calcification, are the main cause of death. However, currently, the only effective cure is to undergo surgery to augment or receive a healthy donor heart, which could be very difficult due to the long waiting list and the associated risks. The possibility of body rejection of the foreign organs is attributed to immunoreaction or the risk of infection, since the donor must be on immunosuppressant drugs that lower the body's immunity and facilitate the body's acceptance of the new organ as one of its own. Taking that into consideration, using tissue-engineered vascular …

Effect Of Cigarette Smoke Extract And Nutrient Deficiency On Energy Metabolism And Biosynthesis: An In Vitro Intervertebral Disc Explant Culture Study, Avery E. Madden

All Theses

Low back pain consistently ranks among the leading causes of disability worldwide, with degenerative changes in spinal intervertebral discs (IVDs) recognized as a key contributor. Degeneration arises from the disruption of mechanical and biological cues within the disc’s cartilaginous tissue, often exacerbated by aging or injury. In recent decades, cigarette smoking has also been identified as a significant risk factor, as IVD degeneration is more prevalent among individuals with a history of smoking. Smoke inhalation is thought to promote degeneration both directly, by exposing cells to water-soluble toxic chemicals in smoke; and indirectly, through nutrient deficiency resulting from vasoconstriction and …

Consumer Preferences For Blockchain Technology In Tracking Carbon Footprint And Organic Claims In Animal-Based Foods, Josie Nasekos

All Theses

In 2022, the United States Department of Agriculture (USDA) Partnerships for Climate-Smart Commodities (PCSC) program set aside over $3 billion to be invested in 141 projects for agricultural products produced using practices that reduce greenhouse gas emissions or increase carbon sequestration. Although the majority of the PCSC funding was canceled in 2025, save a few selected projects that could potentially receive funding under the USDA’s new Advancing Markets for Producers initiative, there is no USDA-certified label to verify the climate-smart commodities that already received funding or similar products that exist in the market. However, third-party verified carbon footprint labels can …

Determining The Impact Of Surface Roughness On Disinfection Efficacy Of Commercial Products Against Pseudomonas Aeruginosa And Staphylococcus Aureus Wet Surface Biofilms, Kayley Stallings

All Theses

Biofilms are resistant to many stressors including disinfectant treatments. Disinfection may be further complicated by biofilms formed on damaged surfaces, as the damaged parts provide bacteria a better place to attach and grow. To better understand the risks, a new method to standardize surface scratching, to emulate worn surfaces via surface roughness changes was developed. These surfaces were used to grow biofilms with an adapted standardized EPA method to determine disinfection efficacy differences on scratched and non-scratched high-density polyethylene (HDPE) and stainless steel (SS) coupons treated with commercial disinfectants [hypochlorite (CL)-based, hydrogen peroxide (HP)-based, and quaternary ammonium (QA)-based]. Post-80 grit …

Quantifying The Effect Of Initial Molecular Weight Distribution On The Degradation Of Linear Polyethylene At High Temperatures Using Dissipative Particle Dynamics, Cassandra L. Simpson

All Theses

Polyolefins are the primary contributors to greenhouse gas emissions and supply chain energy requirements with respect to other commodity polymers. In order to explore more efficient methods for recycling and upcycling these plastics, it is important to consider the kinetics of polymer fragments during the degradation process to more accurately reflect experimental outcomes. The molecular weight distribution of synthetic polymers is an important factor to consider when synthesizing, processing, and manufacturing industrial plastics. The breadth of this distribution, or dispersity, is determined by the ratio of the weight average molecular weight to the number average molecular weight, and is correlated …

3,5-Dihydroxy-4-Isopropylstilbene (Tapinarof) Is A Partial Aryl Hydrocarbon Receptor Agonist In Fish, Conner A. Dicks

All Theses

The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor that is essential in regulating development, immune homeostasis, and drug and xenobiotic metabolism. Activation of the AHR by specific ligands results in its translocation to the nucleus where it induces a myriad of gene products, including cytochrome P450 (CYP) drug metabolizing enzymes (e.g., CYP1A1) and other components of the chemical defensome, as well as inflammatory control. Interestingly, the AHR can bind a wide variety of endogenous and xenobiotic ligands which are able to induce unique downstream effects dependent on cell type, inflammatory context, and ligand stability. The AHR is …

Low Energy Ion Irradiation Effects In Electronic Devices And Materials, David C. Mccall

All Dissertations

The physics and engineering of ion-solid interactions are governed by the ion beam characteristics (flux, charge, energy) and target(s) in question. Here I present work on two projects related to the extraction of a high flux of low charge state Argon ions from a commercial plasma source and the irradiation of an engineered target, a transistor, with high charge state Argon ions.

An end-Hall ion source that produces a a high current plasma of ions and electrons in a rough vacuum environment is characterized. Using a Langmuir probe and multiple pressure measurements, the ion and electron content of the source …

Breeding Biofortified Protein Rich Organic Pulses For Better Human Health, Sonia Salaria

All Dissertations

Pulse crops are dry grains of legumes, the second most consumed plant crops in the world after cereals. These crops are one of the primary sources of plant-based protein and contain high concentrations of pre-biotic carbohydrates, minerals and vitamins. Recognizing the health benefits of pulses intake, their demands as sustainable food and changes in people’s diet preferences for plant-based protein have increased awareness for pulses consumption. With this scenario, improving the nutritional profile of pulse crops for rich nutrition has been an opportunity for breeders to explore and tailor the available germplasm to develop nutrient dense pulses. Furthermore, the genomic …

Impact Of Cysteine And Tyrosine Dipeptides On Cho Cell Performance In A Perfusion Mimic, Corrin L. Pruitt

All Theses

Perfusion cell cultures typically achieve higher cell densities and generate higher volumetric productivities than fed-batch cultures due to continuous nutrient supply and spent media removal. Despite these advantages, perfusion cell cultures remain underutilized for licensed product manufacturing, primarily due to the lack of small-scale perfusion models for high-throughput process development and the complexities involved in media formulation capable of supporting high cell densities during long-term continuous operation. To avoid nutrient limitation at high cell densities, current perfusion processes rely on using higher perfusion rates, which results in significant media wastage and downstream product dilution. Therefore, there has been an effort …

An Exploration Of Elderly Representation & Stereotypes In Animation, Tyler Kidd

All Theses

In the world of animated features, supporting cast members are often reduced down to simple character traits in order to give the audience a simple idea of their personality or role in the story, or to support the creation of a work that is easier to understand for people of all ages. However, this can often result in the application of negative tropes that do not reflect kindly on those being depicted. The elderly are a group that often get caught in these stereotypes, being depicted as wrinkly, clumsy, overweight villains. While you can still find many positive portrayals in …

Striped Bass (Morone Saxatilis) Movement And Habitat Selection In The Edisto River, South Carolina, Jacob Hill

All Theses

Striped Bass (Morone saxatilis) are a commercially and recreationally important fish native to the Atlantic Coast of the United States. They possess a diversity of life history strategies, with northern populations tending to be anadromous and southern populations being primarily river residents. In general, southern populations are less studied, posing challenges for effective management. Between 2019 and 2024, we tagged 37 Striped Bass with acoustic telemetry transmitters in order to study seasonal migration patterns and summer habitat selection. We estimated migration probability for both the spring and fall Striped Bass migrations using data from an array of passive …

Multiple View Neural Regression Of A Facial Shape Model, Xiang Li

All Dissertations

Creating re-topologized 3D facial meshes is a critical step in high-quality facial animation pipelines, yet it remains a labor-intensive and time-consuming task. Traditional approaches typically rely on multiview stereo reconstruction and specialized photometric environments to acquire accurate geometric and reflectance data under controlled conditions. This dissertation presents work toward more efficient capture of production-ready meshes including (1) developmental aspects of VarIS, a custom-designed light sphere capable of capturing high-resolution stereo geometry and reflectance maps—including diffuse, specular, and normal components under programmable illumination; (2) a study of the effects of camera parameters on automatic 2D and 3D landmarking methods, (3) methods …

From Pencil To Pixel: How Leadership Shapes Organizational Responses To Competence-Destroying Technological Change, Jennifer Underwood

All Dissertations

This dissertation examines how managerial leadership enables organizations to overcome inertia during competence-destroying technological change through a historical comparative case analysis of the animation industry's transition from hand-drawn to computer-generated imagery (CGI) between 1980-2000. Drawing on archival data from Disney, Pixar, and Don Bluth Studios, I identify three distinct leadership approaches—pioneering, bridging, and preserving—that differently influenced how workforces adjusted their views of identity, process, and change. These adjustments led to three different outcomes: transformative integration, constrained adoption, and entrenched resistance. This research makes three theoretical contributions and develops a novel framework that explains how leadership can constrain or enable transformation, …

Exploring The Socio-Cultural Dynamics Of Nocturnal Urban Landscapes: A Case Study, Jie Kong

All Dissertations

This dissertation explores nighttime social leisure activities in public parks within urban working- and middle-class communities. As cities confront climate change, shifting work schedules, and post-pandemic lifestyles, neighborhood parks have gained renewed importance after dark, especially in areas where households have limited private space. These non-commercial nighttime uses are often overlooked in planning, design, and built environment studies, yet they play a vital role in fostering cultural identity, social connection, and community well-being.

Focusing on Williamsburg and Bushwick in Brooklyn, New York, this research investigates how public parks are used at night, by whom, and for what purposes. New York …

Ecomorphological Diversification Of Tooth Complexity In The Oral Jaws Of Marine Teleostean Fishes, Keiffer L. Williams

All Dissertations

Teeth are essential biological tools that function as a direct interface between predator and prey, thus providing essential insights into the evolutionary history and ecological diversity of vertebrates. Historically, studies on vertebrate dentitions have been qualitative and focused on mammals. More recently, quantitative methods have been developed that can reliably measure tooth surface complexity. These methods have been applied across both mammals and saurian reptiles to test for correlations with diet, leading to the conclusion that herbivorous species generally possess higher overall tooth complexity than any other dietary group. Surprisingly, the relationship between tooth complexity and diet in the most …

From Cities To Ranches: Assessing Public Support For Jaguar (Panthera Onca) Conservation And Livestock Predation In Colombia, Luz Angelica Solano

All Dissertations

Jaguars are among the most emblematic large carnivores worldwide. Nonetheless, the species has declined by 25% in less than 25 years and their range has been reduced by 55%, approximately, primarily due to habitat loss from increasing agricultural development, retaliatory killings from human-jaguar conflict, and overhunting of their natural prey. Given the anthropogenic nature of these threats, developing effective coexistence strategies and public support for jaguar conservation are increasingly urgent for the continued persistence of this species. I conducted a scoping review to assess trends and gaps in the existing peer-reviewed literature, grey literature, and news articles related to human-jaguar …

Studies On The Effects Of Operator Fatigue On Performance, Trust, And Workload Demand In Human-In-The-Loop Ai-Enabled Drone Systems, Snowil Lopes

All Dissertations

Civil infrastructure must be regularly inspected to ensure its safety and reliability. Traditionally, risk engineers performed these inspections manually and in person. However, with the introduction of drones equipped with artificial intelligence (AI), inspections of civil infrastructure can now be conducted remotely. These AI-enabled drones capture and analyze images, helping engineers monitor large and complex structures from a distance. However, working with integrated systems consisting of multiple drones, especially those with varying levels of reliability, can be challenging. Operators must divide their attention, determine how much to trust each drone, and manage mental workload, which can affect their performance. Another …

Empowering Employability: Voices Of Black Women Leveraging Community Cultural Wealth In An Undergraduate Agricultural Program, Rose Marie Somers

All Dissertations

Across the nation, agricultural industry professionals have bemoaned the shortage of qualified professionals, expressing an expanding need for graduates with a blend of discipline-specific and employability skills to advance the sector. Research indicates that the future of the US agriculture sector hinges on a diverse and skilled workforce. Yet, a paucity of literature exists on Black women's enduring legacy, experiences, and how they understand and develop 21st-century critical transferable professional competencies needed to address complex challenges in modern agriculture. Black women have a long tradition in agriculture and a wealth of cultural knowledge, skills and innovations that are untapped. This …

Advancing Smart And Adaptive Living Spaces Through Design And Development Of Reconfigurable Multifunctional Robot Rooms, Nithesh Kumar

All Dissertations

This work explores and introduces prototype hardware for a new category of robots: ‘Robot Rooms’, in an effort to refine the concept of traditional smart spaces and human-robot interaction. Unlike traditional robots that tend to be compact and exist within a space, this new category of robots is designed to be expansive: they do not exist within a space but rather shape space around them. We present several design concepts for potential robotic elements of a Robot Room. We then develop and demonstrate, at full scale, a new and novel concept: a ‘slice’ of a Robot Room. This slice changes …

Designing Self-Healable Aromatic Copolymers And Olefinic Composites, Samruddhi Yashwant Gaikwad

All Dissertations

Self-healing polymers capable of recovering from mechanical damage are promising materials for advanced applications, especially those involving mechanical and/or physical fatigue. In these studies, we have developed techniques to achieve autonomous self-healing in commodity Styrene/n-butyl acrylate copolymers. The mechanism of self-healing in the designed polymers involves inter-and/or intrachain non-covalent interactions between π-cloud and polar linkages of acrylic nBA in random/preferentially alternating copolymers. A combination of spectroscopic tools, thermo-mechanical analysis, and molecular dynamics (MD) simulations has been used to elucidate the mechanism of self-healing. These studies further show the incorporation of dipolar C-F groups to understand the effect of having fluorinated …

Like Footprints In The Sand: How Founders Imprint Organizational Culture Through Nonverbal Cue Signaling, Dirk M. Roskam

All Dissertations

Despite growing recognition of the significance of founders’ behaviors in shaping organizational culture, limited research has explored how founders’ non-verbal cues (NVCs) imprint culture during a venture’s formative stages. This qualitative case study examines how a founder’s NVCs, ranging from physical environment design to gestures and demeanor, are interpreted by employees and contribute to the imprinting of organizational culture. Drawing on imprinting theory, signaling theory, and the Organizational Culture Profile (OCP), the study triangulates data from semi-structured interviews, a focus group, and a literature review. Findings reveal that employees interpret 24 salient NVCs, grouped into themes of environmental values, people-centric …

The Intersection Of Makeup And Recreation: A 21st Century Overview Of Makeup Participation And Its Recreational Benefits, Jason Morgan

All Dissertations

This dissertation critically reconceptualizes makeup participation as a legitimate, multidimensional form of recreation. Through a comprehensive rapid review using the SPIDER framework of 102 peer-reviewed studies published between 2000 and 2025, the research investigates whether and how makeup fulfills the psychological, affective, and symbolic criteria of meaningful leisure. Drawing on the Serious Leisure Perspective (SLP) and broader recreation theory, the study positions makeup not merely as aesthetic behavior or consumer habit, but as a sustained, emotionally generative practice embedded in identity, creativity, personal growth, and well-being.

Findings reveal that makeup is consistently linked to confidence-building, emotional regulation, self-expression, and psychological …

Evolutionary Biomechanics In Cetartiodactyla: Impacts Of Ecological Shifts On Bone Material Properties And Control Surface Morphology, Danielle S. Adams

All Dissertations

Extreme ecological transitions expose organisms to novel selective pressures that can reshape morphology and performance. This dissertation investigates how the transition from land to water has influenced form and material properties in cetaceans (whales, dolphins, and porpoises), a clade that has undergone dramatic morphological and physiological adaptations to a fully aquatic lifestyle. I integrate comparative morphology, material property testing, and phylogenetic analyses, to explore how ecological demands, particularly related to foraging mode and prey detection, have shaped multiple aspects of cetacean morphology and function. Using nanoindentation and microCT, I measured elastic modulus and bone density of the skull and mandible …