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Articles 4891 - 4920 of 6021
Full-Text Articles in Entire DC Network
Effects Of Arsenic And Uvb Radiation On Induction Of Cyclin D1 In Human Keratinocytes., Julian Gonzalez
Effects Of Arsenic And Uvb Radiation On Induction Of Cyclin D1 In Human Keratinocytes., Julian Gonzalez
Dissertations and Theses
Arsenic and Ultraviolet radiation B (UVB) are environmental toxins that have been linked to various epithelial cancers. Arsenic metabolism in humans leads to its collection in the skin, where it encounters and can act with known carcinogen UVB. Epidemiological evidence of the two toxins demonstrates their potential to affect signaling pathways, with various consequences. Here we employ an in vitro model system using Normal Human Epidermal Keratinocytes (NHEK) to identify the effect of arsenic and UVB on humans and whether they work synergistically. We find that although both cause induction of cyclin D1, culturing cells with both co-mutagens does not …
Multimedia Content-Based Indexing And Recognition In Digital Libraries, Steven Medina
Multimedia Content-Based Indexing And Recognition In Digital Libraries, Steven Medina
Dissertations and Theses
"Recognition of digital media is more prevalent in today’s computer culture than ever before. The advent of low cost storage has created a seemingly infinite amount of metadata on the internet, as well as on local machines throughout the world. It is more important than ever to have the capability of quickly and accurately filtering this metadata to find a desired result. Data can be searched using various criteria. For example, text data is searched by analyzing the contents of the text itself. One might execute a search using a method as simple as looking for the ASCII file name, …
Disclaiming Legitimacy, And The Stories Of Katherine Mansfield, Mathew Mead
Disclaiming Legitimacy, And The Stories Of Katherine Mansfield, Mathew Mead
Dissertations and Theses
No abstract provided.
Neural Correlates Of Phantom Auditory Perception, Paul Joseph S. Deguzman
Neural Correlates Of Phantom Auditory Perception, Paul Joseph S. Deguzman
Dissertations and Theses
No abstract provided.
The Role Of Rugose, A Drosophila Akap And Loco, A Rgs Protein In Synaptogenesis And Development, Kemeh Georgina
The Role Of Rugose, A Drosophila Akap And Loco, A Rgs Protein In Synaptogenesis And Development, Kemeh Georgina
Dissertations and Theses
No abstract provided.
Development Of A Human Lung Cancer Cytochrome C-Gfp Reporter Cell Line To Study Anti-Cancer Drug Responses In Apoptosis Pathways, Sidra A Piracha
Development Of A Human Lung Cancer Cytochrome C-Gfp Reporter Cell Line To Study Anti-Cancer Drug Responses In Apoptosis Pathways, Sidra A Piracha
Dissertations and Theses
"Currently chemotherapy and radiotherapy are the most popular methods for cancer treatments after surgery, but lack of specificity and are thus toxic to the healthy human cells. Studies have shown that targeted therapies have been linked to activation of apoptosis signal pathways (cascade of caspases) in cancer cells including intrinsic and extrinsic pathways. One of the major pathways leading to caspase activation involves the release of cytochrome-c from mitochondria. However, in some tumor cells this pathway is inactivated due to the mutation of mitochondria membrane stabilizing proteins (e.g. Bcl-2, Bcl-xL). Therefore, the overall objective of this proposal was to understand …
Developing A Comprehensive Software Toolkit For Creating Digital Mosaic Artwork, Dmitry Bosikov
Developing A Comprehensive Software Toolkit For Creating Digital Mosaic Artwork, Dmitry Bosikov
Dissertations and Theses
No abstract provided.
Removal Of Antibiotics From Contaminated Waters Using Natural Zeolite, Booyoung Lee
Removal Of Antibiotics From Contaminated Waters Using Natural Zeolite, Booyoung Lee
Dissertations and Theses
The occurrence of residual antibiotics in the environment has been a worldwide issue, and there is a need to develop methods for antibiotics removal from contaminated water. In this thesis work, the sorption of four antibiotics, namely chlortetracycline (CTC), oxytetracycline (OTC), ofloxacin (OFL), and enrofloxacin (ENR), on natural zeolite was investigated. The impact of pH and natural organic matter (NOM) on the sorption process was examined, and the maximum sorption capacity was calculated using the Langmuir-Freundlich sorption model. The results showed that at a neutral pH the maximum sorption capacity for the antibiotics was up to 8 mg/g. The sorption …
Why Oil Production Has A Negative Impact On Socioeconomic Development In Chad?, Annicette Kessely
Why Oil Production Has A Negative Impact On Socioeconomic Development In Chad?, Annicette Kessely
Dissertations and Theses
"Oil production in Chad is considered one of the most important Sub-Saharan investments in Africa. In 2000, the World Bank agreed to finance oil production under the condition that oil revenues would be invested in socioeconomic development projects. Furthermore, the World Bank emphasized that oil revenues should be used in a transparent and accountable matter.1 Oil production started in Chad in 2003 and brought billions of dollars to the government. Nevertheless, the Chadian population continues to live in extreme poverty. The purpose of this paper is to evaluate the impact of oil production on socioeconomic development. It will demonstrate that …
Minority Rights In Europe; The Roma Population As A Case Study, Michael Brooks
Minority Rights In Europe; The Roma Population As A Case Study, Michael Brooks
Dissertations and Theses
"This thesis undertakes an in-depth analysis of the minority rights of Roma populations living within the European Union. The Roma people face economic, social and political discrimination that permeates both government institutions and society in general and has prevented this minority group from integrating into the workings of society. This issue is important because the Roma lack a positive identity both of themselves and from other groups, which deprives the state of an important source of productivity. This is due in part from their own actions based on chosen isolation to some degree, and also because some Roma have become …
The Book Of Adultery, Ali Sa'eed
One Hundred Top Hats, Sharae Allen
Ill Lads On An Odd Sea: A Novel, Timothy C. Niemann
Ill Lads On An Odd Sea: A Novel, Timothy C. Niemann
Dissertations and Theses
No abstract provided.
Junkyard Kingdom, Maureen Daniels
Utility, Daniel Cicala
Winter Cherry, Miriam Ellen Walden
Dead Stars And Empty Calories, Cynthia Maria Vogle
Dead Stars And Empty Calories, Cynthia Maria Vogle
Dissertations and Theses
No abstract provided.
Not Fade Away, Jean Catherine Nastasi
Constance Or The Hideousness Of Deceit, A Mystery In Verse, Jon L. Jensen,
Constance Or The Hideousness Of Deceit, A Mystery In Verse, Jon L. Jensen,
Dissertations and Theses
No abstract provided.
Family Troubles, Jordan Schauer
The Archaeology Of Retribution, Tony Chiarella
The Archaeology Of Retribution, Tony Chiarella
Dissertations and Theses
No abstract provided.
Scribe’S Tale, Jonathan Gabay
Rescue Me, Carolyn Murdaugh
Beautiful Mentirosa, Maria Billini
One Hundred Top Hats, Sharae Allen
Carribean Folk: Engendering The Color Politics Of Claude Mckay's Banana Botttom (1933), Charmaine Dacosta
Carribean Folk: Engendering The Color Politics Of Claude Mckay's Banana Botttom (1933), Charmaine Dacosta
Dissertations and Theses
No abstract provided.
Morphological And Neuroanatomical Changes Associated With The Induction Of Neurodegeneration And Life Span Reduction In Drosophila Melanogaster By Glia Targeted Expression Of Cdh1/Rap/Fzr, An Activator Of The Anaphase Promoting Complex, Israel Nnah
Dissertations and Theses
"The retina aberrant in pattern (rap) gene encodes the Fizzy-related protein (Fzr), an activator of the E3 ubiquitin ligase complex: the Anaphase Promoting Complex/Cyclosome (APC/C). APC/C facilitates the cell cycle stage-specific degradation of cyclins and other mitotic regulators, resulting in the inactivation of Cdk (Cyclin Dependent Kinase) complexes, thus promoting completion of mitosis. Previous studies from our laboratory have shown that Rap/Fzr (the Drosophila homolog of the mammalian Cdh1) regulates glia differentiation and promotes neuron formation. Recent studies have shown that the glia specific over expression of Rap/Fzr causes progressive neurodegeneration and life span reduction preceded by temperature sensitive paralysis, …
History, Interactive Technology And Pedagogy: Past Successes And Future Directions, Stephen Brier
History, Interactive Technology And Pedagogy: Past Successes And Future Directions, Stephen Brier
Publications and Research
Based on a keynote presentation at the 2012 Canadian Historical Association conference, this paper surveys the state of digital technology and its impact on academic publication and teaching in the contemporary university. Focusing on the dramatic rise of the Digital Humanities in the last few years, the paper examines alternative forms of peer review, academic scholarship and publication, and classroom teaching as they have been reshaped by the adoption of a variety of digital technologies and formats, including open-access, online peer reviewing, use of data- bases and visualization techniques in humanities work, online journal publication, and the use of blogs …
The Social Life Of Musical Instruments, Eliot Bates
The Social Life Of Musical Instruments, Eliot Bates
Publications and Research
Accordion Crimes, a novel by E. Annie Proulx, traces the life of and routes travelled by a green diatonic button accordion: its birth in Sicily in the workshop of “The Accordion Maker,” its numerous changes of ownership in the Americas during encounters between various immigrant communities, and its death when it finally falls into disrepair in the town of Old Glory, Minnesota. There are other accordions in the book, and many temporary human owners, but it is one particular green accordion that is the book’s protagonist. We meet and experience other characters largely through their interactions with the green accordion, …
Vitamin D: Implications Of The Institute Of Medicine Report For Clinical Practice, Dorothy Grasso, Margaret A. Rafferty
Vitamin D: Implications Of The Institute Of Medicine Report For Clinical Practice, Dorothy Grasso, Margaret A. Rafferty
Publications and Research
In November 2010, the Institute of Medicine (IOM) released Dietary Reference Intakes for Calcium and Vitamin D, a radical departure from previous advice given regarding these two nutrients that have been reported in respected health journals. The 14-member expert committee found clear and convincing evidence to support the association between adequate levels of vitamin D and bone health. The IOM committee did not find enough evidence to support claims that inadequate levels of vitamin D are linked to increased risks for cancer, cardiovascular disease, or diabetes. In this article, the authors discuss the controversy surrounding vitamin D and provide guidance …