Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

City University of New York (CUNY)

Discipline
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 3061 - 3090 of 6021

Full-Text Articles in Entire DC Network

Vim Parat: Patterns Of Sexualized Violence, Victim-Blaming, And Sororophobia In Ovid, Melissa Marturano Sep 2017

Vim Parat: Patterns Of Sexualized Violence, Victim-Blaming, And Sororophobia In Ovid, Melissa Marturano

Dissertations, Theses, and Capstone Projects

My dissertation argues for the importance of understanding the depiction of sexualized violence and rape in the Roman poet Ovid’s extensive corpus through the modern feminist concepts of victim-blaming (blaming victims of sexual abuse for their own abuse) and sororophobia (female figures participating in misogyny). It explores sexualized violence and rape in Ovid long-form, examines the discernible patterns that emerge and the deviations from them as he depicts that violence throughout his texts, and more importantly, introduces victim-blaming and sororophobia into an analysis of these patterns. Despite the fact that previous scholars have done substantial analyses of the patterns of …


Cognitive And Neurobiological Degeneration Of The Mental Lexicon In Primary Progressive Aphasia, Jet M. J. Vonk Sep 2017

Cognitive And Neurobiological Degeneration Of The Mental Lexicon In Primary Progressive Aphasia, Jet M. J. Vonk

Dissertations, Theses, and Capstone Projects

The ease with which we use the thousands of words in our vocabulary stands in stark contrast to our difficulty establishing how they are organized in our mind and brain. The breakdown of language due to cortical atrophy in primary progressive aphasia (PPA) creates conditions to study this organization at a cognitive and neurobiological level in that the three variants of this disease, namely non-fluent, logopenic, and semantic PPA, each bear their own signature of language-specific decline and cortical atrophy. As the impaired regions in each variant are linked to different lexical and semantic attributes of words, lexical decision performance …


Liberal Translations: Secular Concepts, Law, And Religion In Colonial Egypt, Jeffrey Culang Sep 2017

Liberal Translations: Secular Concepts, Law, And Religion In Colonial Egypt, Jeffrey Culang

Dissertations, Theses, and Capstone Projects

This dissertation is a conceptual history of Egypt’s national formation between the 1880s and the 1930s. This period involved the convergence of nationalism, colonial rule, missionary activity, and new modes of governance at the national and international levels. Drawing on state and missionary archival material, periodicals, legal compendia, laws, and parliamentary transcripts, and adapting methods developed by Reinhart Koselleck, I trace shifts within Egypt’s socio-political lexicon through processes of translation and demonstrate their effects upon social experience and political aspiration. I focus on a set of liberal-secular concepts critical to national politics—religious freedom, public interest, nationality, and the minority—as they …


Modulation Of The Sodium/Potassium Atpase Function And Expression By Transcranial Direct Current Stimulation Of The Right Sensorimotor Cortex In Mice, Salim Bendaoud Sep 2017

Modulation Of The Sodium/Potassium Atpase Function And Expression By Transcranial Direct Current Stimulation Of The Right Sensorimotor Cortex In Mice, Salim Bendaoud

Dissertations, Theses, and Capstone Projects

Direct current stimulation is used as a noninvasive therapeutic technique to enhance motor recovery following stroke, and to improve cognitive functions. This technique also showed promising results in the treatment of depression, schizophrenia, and multiple sclerosis. Transcranial direct current stimulation has been proven to cause a polarization (depolarization or hyperpolarization) of the target tissues depending on the polarity of the current and cell orientation. Because of the induced polarization, the spontaneous activity of the neurons is further affected. With exception to this electrophysiological effect, the overall biological mechanisms of transcranial direct current stimulation on the underlying tissues remain largely unknown. …


Trump’S “America First” Trade Policy And The Politics Of U.S. International Investment Agreements, Jesse Liss Sep 2017

Trump’S “America First” Trade Policy And The Politics Of U.S. International Investment Agreements, Jesse Liss

Dissertations, Theses, and Capstone Projects

Previous sociological studies on U.S. trade policy institutions concluded that “free trade” political actors had durable power to determine U.S. trade policy. This conclusion was proven wrong when the Trump administration promised “a new direction” and to implement an “America First” trade policy. My dissertation serves to explain the U.S.’ political transition away from “free trade” and towards “nationalist” trade policy. I do this by examining the politics of U.S. international investment agreements, which are central to U.S. trade policy. As case studies, I use the investment agreements from the North American Free Trade Agreement (NAFTA) and the Trans-Pacific Partnership …


Walking As Ontological Shifter: Thoughts In The Key Of Life, Bibi (Silvina) Calderaro Sep 2017

Walking As Ontological Shifter: Thoughts In The Key Of Life, Bibi (Silvina) Calderaro

Dissertations, Theses, and Capstone Projects

With walking as ontological shifter I pursue an alternative to the dominant modernist episteme that offers either/or onto-epistemologies of opposition and their reifying engagements. I propose this type of walking is an intentional turning towards a set of radical positions that, as integrative aesthetic and therapeutic practice, brings multiplicity and synchronicity to experience and being in an expanded sociality. This practice facilitates the conditions of possibility for recurring points of contact between the interiority perceived as ‘body’ and the exteriority perceived as ‘world.’ While making evident the self’s at once incoherence with it-self, it opens to a space beyond the …


Involute Analysis: Virtual Discourse, Memory Systems And Archive In The Involutes Of Thomas De Quincey, Kimberley A. Garcia Sep 2017

Involute Analysis: Virtual Discourse, Memory Systems And Archive In The Involutes Of Thomas De Quincey, Kimberley A. Garcia

Dissertations, Theses, and Capstone Projects

Thomas De Quincey’s involutes inform metaphysical thought on memory and language, particularly concerning multiplicity and the virtual, repetition and difference. When co-opting the mathematic and mechanic involute in Suspiria de Profundis, De Quincey generates an interdisciplinary matrix for the semiotics underpinning his philosophy of language and theory of memory and experience. Involutes entangle and reproduce. De Quincey’s involute exposes the concrete and actual through which all experience accesses the abstract or virtual. The materiality of their informatics and technics provides a literary model and theoretical precursor to a combination of archive and systems theory. The textuality of involute system(s)—both …


Claude Iii Audran: Ornemaniste Of The Rococo Style, Barbara Laux Sep 2017

Claude Iii Audran: Ornemaniste Of The Rococo Style, Barbara Laux

Dissertations, Theses, and Capstone Projects

The ornemaniste Claude III Audran worked over the course of some forty years to delight elite aristocrats, including Louis XIV, by creating cutting-edge arabesque designs with motifs drawn from popular culture. He became a maître in the Académie de Saint-Luc. He chose not to become a member of the Académie royale de peinture et sculpture, but he subcontracted work to Académie artists and achieved unparalleled status as a master of his craft. Despite the longevity of his successful career, previous scholarship has only examined a handful of individual projects and the arc of his career has never been fully examined. …


Social Media Use And Media Literacy In Relation To Adolescents' Understanding Of The Internet, Kasey L. Powers Sep 2017

Social Media Use And Media Literacy In Relation To Adolescents' Understanding Of The Internet, Kasey L. Powers

Dissertations, Theses, and Capstone Projects

Digital media has permeated American culture among users of all ages. By early adolescence, youth are using and consuming media at unprecedented rates. While the majority of content consumed remains largely television and movies, often streamed through new channels like Amazon and YouTube, video games and apps also comprise a portion of the media diet. As youth enter adolescence, their usage of social media, defined as any platform that allows interactive communication in response to online posting, becomes more prevalent.

In this study, I explore Internet and social media use and its impact on adolescents’ understanding of media in three …


Distribution And Activation Of Catecholaminergic Neurons In The Brain Of Male Plainfin Midshipman Fish: Divergence In Behavior And Reproductive Phenotype, Zachary Ghahramani Sep 2017

Distribution And Activation Of Catecholaminergic Neurons In The Brain Of Male Plainfin Midshipman Fish: Divergence In Behavior And Reproductive Phenotype, Zachary Ghahramani

Dissertations, Theses, and Capstone Projects

The plainfin midshipman fish, Porichthys notatus, provides an excellent opportunity for delimiting the influence of neurochemical content on vertebrate vocal behavior, in part because the production and recognition of social-acoustic signals is vital to their reproductive behavior. There are two distinct reproductive male morphs that follow divergent developmental trajectories with corresponding alternative reproductive tactics: type I males are the territorial/nesting morph that vocally court females during the summer breeding season while type II males do not court females, but instead sneak spawn in competition with type I males. Catecholaminergic neurons, which synthesize and release the neurotransmitters dopamine or noradrenaline, …


A Realization Of Modernity: Case Studies In Connectivity And Time, Mari Gorman Sep 2017

A Realization Of Modernity: Case Studies In Connectivity And Time, Mari Gorman

Dissertations, Theses, and Capstone Projects

My stated goal in applying to The Graduate Center was to explore my previous research in diverse fields of study. This research, the result of a formal investigation of acting, was and still is centrally focused on the subject of relationship itself, relationships being what actors create. In pursuit of a greater understanding of the essential nature of relationship in practical terms, a self-organizing complex system that constitutes universal relationship was unexpectedly discovered. As such, this system has been shown to offer solutions to many outstanding problems in diverse areas of study. The Liberal Studies program track, Approaches to Modernity …


Behavioral Responses To Pulses Of Light In The Longfin Inshore Squid, Doryteuthis Pealeii (Lesueur, 1821), Stavros P. Hadjisolomou Sep 2017

Behavioral Responses To Pulses Of Light In The Longfin Inshore Squid, Doryteuthis Pealeii (Lesueur, 1821), Stavros P. Hadjisolomou

Dissertations, Theses, and Capstone Projects

The coleoid cephalopods (octopus, squid, and cuttlefish) are masters of rapid, adaptive camouflage. Unlike the slower hormonal chromatophore control of flatfish and chameleons, coleoid mollusks can change body patterns in milliseconds. Visual camouflage in coleoids is driven by a sensorimotor system consisting of visual input of their surroundings, a sophisticated central nervous system for information processing, and a neuromuscular control for body patterning. Motor neurons selectively activate millions of muscles, alternately expanding and reducing the pigmented chromatophores to generate visible brown, red, orange and yellow patterns on the skin. Below the chromatophore-layered skin are two types of reflecting cells, iridophores …


Mapping How Culture In New York City And London Influences Respectively The Iconic Fashion Brands Of Kors And Mcqueen: A Case Study, Carol Brathwaite Sep 2017

Mapping How Culture In New York City And London Influences Respectively The Iconic Fashion Brands Of Kors And Mcqueen: A Case Study, Carol Brathwaite

Dissertations, Theses, and Capstone Projects

This thesis is an explanatory case study that applies geographic information systems (GIS) data, biographical data, and other secondary data. It includes mainly qualitative data collection and analysis; furthermore, the study examines quantitative data on the cultural events offered within each city. Overall, this case study adopts a theoretical perspective. The two individual cases (based on a multiple, holistic case-study design framework) of fashion culture in New York City and London, as per Michael Kors and Alexander McQueen respectively, represent ‘confirmatory cases or presumed replications of the same phenomenon’ (Yin 2014:59). Each describes the house’s fashion aesthetics as well as …


One Endless Dance: Tanaka Min's Experimental Practice, John (Zack) Fuller Sep 2017

One Endless Dance: Tanaka Min's Experimental Practice, John (Zack) Fuller

Dissertations, Theses, and Capstone Projects

This work is the first in-depth study of the work of avant-garde Japanese dancer/choreographer Tanaka Min, and focuses on his extensive innovations in the fields of improvised dance, training, and choreographic method. These interrelated aspects of his experimental practice are intimately concerned with the relation between space and the body, employ collaborative methods, and are strongly influenced by the life and work of Hijikata Tatsumi (widely to considered to be the founder of the butô movement). They are also deeply informed by his choice to live his daily life as an organic vegetable farmer, a choice that I argue constitutes …


Ecologies Of Embodied Minds Embedded: Radical Romantic Perspectives On Architectures Of Technology, Sharmaine Browne Sep 2017

Ecologies Of Embodied Minds Embedded: Radical Romantic Perspectives On Architectures Of Technology, Sharmaine Browne

Dissertations, Theses, and Capstone Projects

This dissertation explores Romantic responses to the role of architectural technologies in the development of material being, consciousness, and culture by applying a critical approach in which I combine radical embodied cognitive theory, ecocritical perspectives, and a phenomenological lens to select Romantic texts written from 1789 to 1884 in response to industrial modernity. While scholarship has thoroughly explored technology as a cultural force which inevitably shapes consciousness, I propose that a slight shift of emphasis from technology’s external influence to the material internalization of its influence allows for new perspectives—particularly in light of recent proposals in cognitive philosophy which assert …


Never Forgets: Traumatic Trace Within Public Space, Jan Descartes Sep 2017

Never Forgets: Traumatic Trace Within Public Space, Jan Descartes

Dissertations, Theses, and Capstone Projects

This paper will interrogate the ways in which ephemera from events affects the human and non- human environment and how the absence, manipulation or presence of traumatic trace weaves itself into the atmosphere of the past, present and future. It will look at space and the ways that trace manifests itself in hierarchal spaces and Lebbeus Woods’ concept of heterarchial spaces, which are organic and/or horizontally organized. A thread throughout is the question that if trace from trauma can exist in the visual field, i.e. the physical or digital landscape, in a way that maintains a discourse without perpetuating oppression. …


Jazz And Recording In The Digital Age: Technology, New Media, And Performance In New York And Online, Dean S. Reynolds Sep 2017

Jazz And Recording In The Digital Age: Technology, New Media, And Performance In New York And Online, Dean S. Reynolds

Dissertations, Theses, and Capstone Projects

This dissertation is a study of the uses of recording technologies and new media by jazz musicians in New York. It privileges the perspectives of professional musicians, gleaned through interviews and observation of their discourses and practices in live and recorded performances and in online new media spaces. Contrary to scholarly and critical approaches to jazz that privilege live performance, this dissertation argues that mediatization, through use of recording technologies, digital formats and platforms, and social media, is a vital mode of jazz performance in the digital age. Chapter 1 shows how formative encounters with jazz by musicians coming of …


Of Stars And Solitude: Two Mexican Documentaries, Paul Julian Smith Sep 2017

Of Stars And Solitude: Two Mexican Documentaries, Paul Julian Smith

Publications and Research

By happy coincidence, Mexico in 2016 yielded two expert and moving documentaries on women, sex, and aging: María José Cuevas’s Bellas de noche (Beauties of the Night) and Maya Goded’s Plaza de la Soledad (Solitude Square). Both are first-time features by female directors. And both are attempts to reclaim previously neglected subjects: showgirls of the 1970s and sex workers in their seventies, respectively. Moreover, lengthy production processes in which the filmmakers cohabitated with their subjects have resulted in films that are clearly love letters to their protagonists.


Studying The Mechanisms Of Developmental Vocal Learning And Adult Vocal Performance In Zebra Finches Through Lentiviral Injection, Zhimin Shi, Ofer Tchernichovski, Xiaoching Li Sep 2017

Studying The Mechanisms Of Developmental Vocal Learning And Adult Vocal Performance In Zebra Finches Through Lentiviral Injection, Zhimin Shi, Ofer Tchernichovski, Xiaoching Li

Publications and Research

Here we provide a detailed step-by-step protocol for using lentivirus to manipulate miRNA expression in Area X of juvenile zebra finches and for analyzing the consequences on song learning and song performance. This protocol has four parts: 1) making the lentiviral construct to overexpress miRNA miR-9; 2) packaging the lentiviral vector; 3) stereotaxic injection of the lentivirus into Area X of juvenile zebra finches; 4) analysis of song learning and song performance in juvenile and adult zebra finches. These methods complement the methods employed in recent works that showed changing FoxP2 gene expression in Area X with lentivirus or adeno-associated …


Music In Haredi Jewish Life: Liquid Modernity And The Negotiation Of Boundaries In Greater New York, Gordon A. Dale Sep 2017

Music In Haredi Jewish Life: Liquid Modernity And The Negotiation Of Boundaries In Greater New York, Gordon A. Dale

Dissertations, Theses, and Capstone Projects

In this dissertation I seek to understand tensions regarding boundary maintenance, music, and cultural continuity among the contemporary Haredi (“Ultra-Orthodox”) Jewish community of Greater New York in the context of sociologist Zygmunt Bauman’s theory of liquid modernity. While Bauman suggests that modernity has melted familiar institutions and created an unstable and rapidly shifting world, I argue that for Haredim, the non-liberal religious community and its cultural productions solidify social bonds. While many Haredi Jews strive to continue the musical practices of pre-WWII Europe, some Haredi musicians push or disregard the boundaries of accepted practice by experimenting with Western popular music …


Song Rhythm Development In Zebra Finches, Julia Hyland Bruno Sep 2017

Song Rhythm Development In Zebra Finches, Julia Hyland Bruno

Dissertations, Theses, and Capstone Projects

This dissertation investigates song-rhythm learning in songbirds. Songbirds have been studied extensively in mechanistic investigations into the sensorimotor underpinnings of the cultural transmission of learned vocalizations. While several studies identified forebrain song-system neurons that generate rhythmic song patterns, we know little about how song rhythms are learned. The first part of the dissertation describes methods for detecting and analyzing birdsong rhythm patterns, and demonstrates their utility for identifying the role of song rhythms in social interactions. Results suggest that rhythm plasticity in zebra finch song may provide a potential vehicle for communication. Controlled song-learning experiments further found that developing zebra …


The Fight For Legal Recognition Of Same-Sex Parenting Rights In The United States, Nancy Tresil Sep 2017

The Fight For Legal Recognition Of Same-Sex Parenting Rights In The United States, Nancy Tresil

Dissertations, Theses, and Capstone Projects

This thesis focuses on how same sex couples within the United States claim specific parenting rights and to what extent can law promote social change. Since certain beliefs, values, and behaviors are accepted by some cultural groups or organizations in a society, many same sex couples believe that they should obtain an equal amount of legal entitlement instead of being limited or restricted from certain rights. The theoretical approach incorporates the concepts of legal consciousness and the importance of legal recognition. Legal consciousness is a form of legal awareness and empowerment of people involving issues in regards to the law. …


Heavy Ink: A Documentary On The Comicbook Revolution, Renzo Adler Sep 2017

Heavy Ink: A Documentary On The Comicbook Revolution, Renzo Adler

Dissertations, Theses, and Capstone Projects

Heavy Ink is a documentary short focusing on the comic anthology magazine, Heavy Metal, examining its history as both a standout comic magazine, and how it fits into the larger tradition of comic books. What started off in 1977 as a sci-fi offshoot of National Lampoon ushered in a new era of comics by bridging the gap between American and European comic sensibilities with a talent pool from all over the world.

Heavy Metal would go on to have reverberations beyond comics into music, movies, and the global entertainment landscape of today. Heavy Metal introduced the world to artists such …


La Symbolique Païenne Dans L'Oeuvre De René Depestre, Wilson Decembre Sep 2017

La Symbolique Païenne Dans L'Oeuvre De René Depestre, Wilson Decembre

Dissertations, Theses, and Capstone Projects

My goal in this thesis is to show that the different metamorphoses of René Depestre’s works can be schematized under two determinant stages in which the author’s paganism has different functions and significations. In the first stage, his paganism gives him the tools for his revolt that is purely artistic and existential before it becomes political on account of the author’s discovery of the socialist realism. In the second stage that follows the break of Depestre with Marxism as well as his reevaluation of the Négritude ideology, his paganism becomes truly Dionysian, in the Nietzschean sense of the word, to …


Climate Matching Drives Spread Rate But Not Establishment Success In Recent Unintentional Bird Introductions, Pedro Abellán, José L. Tella, Martina Carrete, Laura Cardador, José D. Anadón Aug 2017

Climate Matching Drives Spread Rate But Not Establishment Success In Recent Unintentional Bird Introductions, Pedro Abellán, José L. Tella, Martina Carrete, Laura Cardador, José D. Anadón

Publications and Research

Understanding factors driving successful invasions is one of the cornerstones of invasion biology. Bird invasions have been frequently used as study models, and the foundation of current knowledge largely relies on species purposefully introduced during the 19th and early 20th centuries in countries colonized by Europeans. However, the profile of exotic bird species has changed radically in the last decades, as birds are now mostly introduced into the invasion process through unplanned releases from the worldwide pet and avicultural trade. Here we assessed the role of the three main drivers of invasion success (i.e., event-, species-, and location-level factors) on …


International Society Of Sports Nutrition Position Stand: Nutrient Timing, Chad M. Kerksick, Shawn Arent, Brad J. Schoenfeld, Jeffrey R. Stout, Bill Campbell, Colin D. Wilborn, Lem Taylor, Doug Kalman, Abbie E. Smith-Ryan, Richard B. Krieder, Darryn Willoughby, Paul J. Arciero, Trisha A. Vandusseldorp, Michael J. Ormsbee, Robert Wildman, Mike Greenwood, Tim N. Ziegenfuss, Alan A. Aragon, Jose Antonio Aug 2017

International Society Of Sports Nutrition Position Stand: Nutrient Timing, Chad M. Kerksick, Shawn Arent, Brad J. Schoenfeld, Jeffrey R. Stout, Bill Campbell, Colin D. Wilborn, Lem Taylor, Doug Kalman, Abbie E. Smith-Ryan, Richard B. Krieder, Darryn Willoughby, Paul J. Arciero, Trisha A. Vandusseldorp, Michael J. Ormsbee, Robert Wildman, Mike Greenwood, Tim N. Ziegenfuss, Alan A. Aragon, Jose Antonio

Publications and Research

Position statement: The International Society of Sports Nutrition (ISSN) provides an objective and critical review regarding the timing of macronutrients in reference to healthy, exercising adults and in particular highly trained individuals on exercise performance and body composition. The following points summarize the position of the ISSN: 1. Nutrient timing incorporates the use ofmethodical planning and eating ofwhole foods, fortified foods and dietary supplements. The timing of energy intake and the ratio of certain ingestedmacronutrientsmay enhance recovery and tissue repair, augmentmuscle protein synthesis (MPS), and improvemood states following high-volume or intense exercise. 2. Endogenous glycogen stores are maximized by following …


Colleges Need To Prepare For Generation Alpha., Aldemaro Romero Jr. Aug 2017

Colleges Need To Prepare For Generation Alpha., Aldemaro Romero Jr.

Publications and Research

The 19th century American theologian and

author James Freeman Clarke is credited with

coining the phrase, “A politician thinks of the

next election. A statesman, of the next generation.”

Although higher education in this country

is currently embattled on many fronts, that should

not distract us from looking years ahead to figure

out how we can prepare for new generations of

students.

One of those upcoming generations has been

labeled “Generation Alpha,” a term crafted by

Mark McCrindle, an Australian social researcher,

demographer and futurist. Unlike “Generation Z,”

born in the mid 1990s and who are today’s college

students, generation …


The Farnesoid X Receptor Negatively Regulates Osteoclastogenesis In Bone Remodeling And Pathological Bone Loss, Ting Zheng, Ju-Hee Kang, Jung-Sun Sim, Jung-Woo Kim, Jeong-Tae Koh, Chan Soo Shin, Hyungsik Lim, Mijung Yim Aug 2017

The Farnesoid X Receptor Negatively Regulates Osteoclastogenesis In Bone Remodeling And Pathological Bone Loss, Ting Zheng, Ju-Hee Kang, Jung-Sun Sim, Jung-Woo Kim, Jeong-Tae Koh, Chan Soo Shin, Hyungsik Lim, Mijung Yim

Publications and Research

Farnesoid X receptor (FXR, NR1H4) is a member of the nuclear receptor superfamily of ligand-activated transcription factors. Since the role of FXR in osteoclast differentiation remains ill-defined, we investigated the biological function of FXR on osteoclastogenesis, using FXR-deficient mice. We demonstrated that FXR deficiency increases osteoclast formation in vitro and in vivo. First, FXR deficiency was found to accelerate osteoclast formation via down-regulation of c-Jun N-terminal kinase (JNK) 1/2 expression. Increased expression of peroxisome proliferator-activated receptor (PPAR)γ and peroxisome proliferator-activated receptor gamma coactivator 1 (PGC- 1)β seems to mediate the pro-osteoclastogenic effect of FXR deficiency via the JNK pathway. In …


Strategies For Improving Approximate Bayesian Computation Tests For Synchronous Diversification, Isaac Overcast, Justin C. Bagley, Michael J. Hickerson Aug 2017

Strategies For Improving Approximate Bayesian Computation Tests For Synchronous Diversification, Isaac Overcast, Justin C. Bagley, Michael J. Hickerson

Publications and Research

Background: Estimating the variability in isolation times across co-distributed taxon pairs that may have experienced the same allopatric isolating mechanism is a core goal of comparative phylogeography. The use of hierarchical Approximate Bayesian Computation (ABC) and coalescent models to infer temporal dynamics of lineage co-diversification has been a contentious topic in recent years. Key issues that remain unresolved include the choice of an appropriate prior on the number of co-divergence events (Ψ), as well as the optimal strategies for data summarization.

Methods: Through simulation-based cross validation we explore the impact of the strategy for sorting summary statistics and the choice …


The Heat Shock Response And Humoral Immune Response Are Mutually Antagonistic In Honey Bees, Mia Mckinstry, Charlie Chung, Henry Truong, Brittany A. Johnston, Jonathan W. Snow Aug 2017

The Heat Shock Response And Humoral Immune Response Are Mutually Antagonistic In Honey Bees, Mia Mckinstry, Charlie Chung, Henry Truong, Brittany A. Johnston, Jonathan W. Snow

Publications and Research

The honey bee is of paramount importance to humans in both agricultural and ecological settings. Honey bee colonies have suffered from increased attrition in recent years, stemming from complex interacting stresses. Defining common cellular stress responses elicited by these stressors represents a key step in understanding potential synergies. The proteostasis network is a highly conserved network of cellular stress responses involved in maintaining the homeostasis of protein production and function. Here, we have characterized the Heat Shock Response (HSR), one branch of this network, and found that its core components are conserved. In addition, exposing bees to elevated temperatures normally …