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Using Rna Sequencing Methodologies To Uncover Common Pathways In Neural Tube Defects: A Comparative Study Of Three Oxidative Neurotoxicants, Aubrey Coleen Johansen Jun 2024

Using Rna Sequencing Methodologies To Uncover Common Pathways In Neural Tube Defects: A Comparative Study Of Three Oxidative Neurotoxicants, Aubrey Coleen Johansen

Theses and Dissertations

Neural tube defects (NTDs) are the second most common type of congenital birth defect that affect infants worldwide. There are several proposed mechanisms for NTDs, but no definitive mechanism has yet been described. One possible mechanism is oxidative disruption of normal developmental signaling. The purpose of this study is to culture whole mouse embryos with three common developmental toxicants, mono-2-ethylhexyl phthalate (MEHP, a plastic pollutant), Fumonisin B1 (FB1, a corn mold), and valproic acid (VPA, an anticonvulsant drug), all of which are known to cause NTDs, and compare their shifts in redox potential and changes to important signaling pathways through …


Black Stereotypes In Basketball Films, Carsen Jackson Williams Jun 2024

Black Stereotypes In Basketball Films, Carsen Jackson Williams

Theses and Dissertations

This study conducts a frequency analysis on the Black stereotypes portrayed in popular basketball films through the lens of media framing. Academic literature has made a frequent topic of racial bias and its role in professional sports, particularly through sports media. However, there is a gap in the literature when looking specifically at basketball films as a whole and the prevalence therein of racial stereotypes, specifically Black stereotypes. Using framing theory as the backbone of the study, a frequency analysis was completed of main characters in the ten most popular basketball films to identify what Black Stereotypes arise. Most common …


Identifying Barriers To Sustainability Of Dual Language Immersion Programs In Utah Schools, Jennifer Leigh Rowley May 2024

Identifying Barriers To Sustainability Of Dual Language Immersion Programs In Utah Schools, Jennifer Leigh Rowley

Theses and Dissertations

Dual Language Immersion (DLI) educational programming began in Utah in 2008. Within three short years, DLI programs in Utah schools had grown from 5 to 58 programs statewide. Presently, Utah now has over 301 DLI programs, including instruction in Spanish, Chinese, French, Portuguese, Russian, and German. DLI programs have many benefits and have attracted many student families. However, not much research has been done on program planning, implementation, and the sustainability of DLI programs within individual school cultures and climates. This study will examine the satisfaction level of faculty, staff, administrators, and parents at DLI schools (including how supported/understood each …


Exploring The Gap Between Self-Assessed And Actual Language Proficiency: A Comparative Analysis Of Japanese And Romance Language Learners, Megan Scarlet Keys May 2024

Exploring The Gap Between Self-Assessed And Actual Language Proficiency: A Comparative Analysis Of Japanese And Romance Language Learners, Megan Scarlet Keys

Theses and Dissertations

This study explores self-assessment accuracy among Japanese second language (L2) learners compared to learners of Romance languages. This research aims to investigate the extent of accuracy in self-assessment among Japanese learners and compare it with their counterparts studying Romance languages. Additionally, the study explores the variables influencing the accuracy of self-assessment in this context. The participants in this study comprised 144 undergraduate students enrolled in Japanese, French, Spanish, or Portuguese courses at Brigham Young University. Most participants possessed practical experience using their L2 in the target cultural context, complementing their academic coursework. The Language Ability Self-Evaluation Resource (LASER) was utilized …


Minimal Specialization: The Coevolution Of Network Structure And Dynamics, Annika King May 2024

Minimal Specialization: The Coevolution Of Network Structure And Dynamics, Annika King

Theses and Dissertations

The changing topology of a network is driven by the need to maintain or optimize network function. As this function is often related to moving quantities such as traffic, information, etc., efficiently through the network, the structure of the network and the dynamics on the network directly depend on the other. To model this interplay of network structure and dynamics we use the dynamics on the network, or the dynamical processes the network models, to influence the dynamics of the network structure, i.e., to determine where and when to modify the network structure. We model the dynamics on the network …


Debunking 'Pfeiffer' S Bacillus': Twentieth Century Germ Theory And The 1918 Influenza Epidemic, Conor Tyson May 2024

Debunking 'Pfeiffer' S Bacillus': Twentieth Century Germ Theory And The 1918 Influenza Epidemic, Conor Tyson

The Thetean: A Student Journal for Scholarly Historical Writing

In the midst of World War I, a scourge swept the world that proved more deadly than any military battle. Between June 1918 and May 1919, three waves of influenza struck in a worldwide pandemic. The origins of this particular influenza strain remain mysterious even today, but it spread so far and fast that only St. Helena in the Atlantic and several south Pacific islands avoided any infection of this flu. The rest of the globe witnessed a deadly killer. Scientists estimate that 50 to 100 million people died from this pandemic, far more deaths than from the five years …


The Impact Of Divided Attention Tasks On Stress: Insights From Heart Rate Variability And Galvanic Skin Response, Kira Stefanie Uluave May 2024

The Impact Of Divided Attention Tasks On Stress: Insights From Heart Rate Variability And Galvanic Skin Response, Kira Stefanie Uluave

Theses and Dissertations

This study examined the impact of divided attention tasks on stress using physiologic measures. The divided attention conditions included speech tasks (conversation or procedural discourse) and non-speech computer-based tasks (visuospatial, mathematical, language, data entry, or text editing). Participants included 60 adults divided into two groups of 30 by age. The young adult group ranged in age from 18-30 years and the older adults ranged from 55-82 years. Participants were required to perform the speech task and the non-speech task in isolation as well as a speech task performed concurrently with each of the non-speech tasks. The order of the tasks …


Dna-Templated Nanofabrication Of Metal-Semiconductor Heterojunctions And Their Electrical Characterization, Chao Pang May 2024

Dna-Templated Nanofabrication Of Metal-Semiconductor Heterojunctions And Their Electrical Characterization, Chao Pang

Theses and Dissertations

Bottom-up nanofabrication, although still in its early stages with formidable challenges, is considered a potential alternative method to address the limitations of traditional top-down techniques by offering benefits including process simplification, cost reduction, and environmental friendliness. DNA-templated nanofabrication, one of the most powerful bottom-up methods, presents an innovative way to create advanced nanoelectronics. In this approach, nanomaterials with specific electronic, photonic, or other functions are precisely and programmably positioned on DNA nanostructures from a disordered collection of smaller parts. These self-assembled structures offer significant potential for improving many fields such as biosensing, drug delivery and electronic device manufacturing. This dissertation …


Jrw Spring 2024 Volume 10 Issue 1 May 2024

Jrw Spring 2024 Volume 10 Issue 1

Journal of Response to Writing

No abstract provided.


Generous Audience, Activist, Evaluator: Tutor-Teachers’ Knowledge, Practices, And Values For Response To Writing, Carolyn Wisniewski May 2024

Generous Audience, Activist, Evaluator: Tutor-Teachers’ Knowledge, Practices, And Values For Response To Writing, Carolyn Wisniewski

Journal of Response to Writing

The relationship between tutoring and teaching has been a recurrent topic of interest among writing center directors and writing program administrators. While scholarship agrees tutoring experience aids composition teachers with implementing process pedagogy and fostering a collaborative classroom, the relationship between tutoring and assessment of student writing is less clear. This qualitative study uses interviews with eight graduate teaching assistants with tutoring experience to examine how they transfer and juxtapose knowledge, practices, and values for response between the writing center and classroom. Like previous scholarship, this research finds writing center tutoring contributes to teachers’ enactment of constructivist, student-centered pedagogy and …


End Matter, Vol. 15 May 2024

End Matter, Vol. 15

Monographs of the Western North American Naturalist

No abstract provided.


Intervening For A Better Social Life? A Comparative Analysis Of Psychological Egoism And Aristotle As Alternate Foundations For Applied Social Psychology's Aims, Samuel D. Major May 2024

Intervening For A Better Social Life? A Comparative Analysis Of Psychological Egoism And Aristotle As Alternate Foundations For Applied Social Psychology's Aims, Samuel D. Major

Theses and Dissertations

The scientific aim which distinguishes applied social psychological research from basic social psychological research is that of using social psychological theory to develop interventions meant to rectify social and practical problems in hopes of fostering a flourishing or thriving social sphere. In developing their interventions, however, many applied social psychologists have failed to consider their pre-investigatory philosophical commitments, commitments which imply the kind of flourishing social life that may come as a result of interventions rooted in them. The aim of this dissertation is to invite applied social psychologists to consider if their frequently noted, yet often unexamined, commitment to …


Front Matter, Vol. 15 May 2024

Front Matter, Vol. 15

Monographs of the Western North American Naturalist

No abstract provided.


Maturation Of An Off-Channel Habitat Concept To Conserve Native Fishes In The Lower Colorado River, Paul C. Marsh, Thomas E. Dowling, Thomas F. Turner, Megan J. Osborne, Brian R. Kesner May 2024

Maturation Of An Off-Channel Habitat Concept To Conserve Native Fishes In The Lower Colorado River, Paul C. Marsh, Thomas E. Dowling, Thomas F. Turner, Megan J. Osborne, Brian R. Kesner

Monographs of the Western North American Naturalist

Two endemic, “large river” fishes of the Colorado River basin of western North America, bonytail Gila elegans and razorback sucker Xyrauchen texanus, are among several critically endangered species in the system. Wild populations of bonytail are gone, and there are no self-sustaining populations of razorback sucker anywhere; reproduction occurs but recruitment does not. Both species have been under intensive management in the Lower Colorado River since the 1980s. Today, with the single exception of Lake Mead, remaining populations are composed entirely of repatriated individuals that depend on stocking for their continued existence. In 2003, a conceptual off-channel habitat (OCH) …


Elizabeth As Constantine: John Foxe And Holy Women, Courtney Jensen Peacock May 2024

Elizabeth As Constantine: John Foxe And Holy Women, Courtney Jensen Peacock

The Thetean: A Student Journal for Scholarly Historical Writing

One of the most frequently discussed issues in Renaissance feminist scholarship is the degree of authority and influence women held in their respective societies. During the sixteenth century, the most obvious indication of female power was the dramatic appearance of powerful female regents and monarchs. This was especially apparent in England, with Jane Gray, Mary Tudor, and Elizabeth Tudor each succeeding to the throne and initiating a succession of female domination for almost fifty years. Whereas women had been traditionally excluded from civil and religious authority, the advent of these female ru lers initiated a new discussion concerning the rights …


Engineering The Signal Resolution Of A Paper-Based Cell-Free Glutamine Biosensor With Genetic Engineering, Metabolic Engineering, And Process Optimization, Tyler J. Free, Joseph P. Talley, Chad D. Hyer, Catherine J. Millar, Joel S. Griffitts, Bradley Charles Bundy May 2024

Engineering The Signal Resolution Of A Paper-Based Cell-Free Glutamine Biosensor With Genetic Engineering, Metabolic Engineering, And Process Optimization, Tyler J. Free, Joseph P. Talley, Chad D. Hyer, Catherine J. Millar, Joel S. Griffitts, Bradley Charles Bundy

Faculty Publications

Specialized cancer treatments have the potential to exploit glutamine dependence to increase patient survival rates. Glutamine diagnostics capable of tracking a patient’s response to treatment would enable a personalized treatment dosage to optimize the tradeoff between treatment success and dangerous side effects. Current clinical glutamine testing requires sophisticated and expensive lab-based tests, which are not broadly available on a frequent, individualized basis. To address the need for a low-cost, portable glutamine diagnostic, this work engineers a cell-free glutamine biosensor to overcome assay background and signal-to-noise limitations evident in previously reported studies. The findings from this work culminate in the development …


Manchester And The Lit And Phil, Nik Vigil May 2024

Manchester And The Lit And Phil, Nik Vigil

The Thetean: A Student Journal for Scholarly Historical Writing

In writing his extensive History, Directory, and Gazetteer of the County Palatine of Lancaster, Edward Baines wrote, "When the increase of wealth and population lead to the establishment of societies for the improvement of the mind and the extension of science, they produce their legitimate influence; of this nature is the Manchester Literary and Philosophical Society." The Lit and Phil, as it was most commonly known, was established in 1781 as a society intended for the discussion of topics as diverse as experimental chemistry and the commercial arts. The Lit and Phil was unique in that it was begun …


Acoustofluidic Scanning Fluorescence Nanoscopy With A Large Field Of View, Geonsoo Jin, Neil Upreti, Joseph Rich, Jianping Xia, Chenglong Zhao, Tony Jun Huang May 2024

Acoustofluidic Scanning Fluorescence Nanoscopy With A Large Field Of View, Geonsoo Jin, Neil Upreti, Joseph Rich, Jianping Xia, Chenglong Zhao, Tony Jun Huang

Faculty Publications

Large-field nanoscale fluorescence imaging is invaluable for many applications, such as imaging subcellular structures, visualizing protein interactions, and high-resolution tissue imaging. Unfortunately, conventional fluorescence microscopy requires a trade-off between resolution and field of view due to the nature of the optics used to form the image. To overcome this barrier, we developed an acoustofluidic scanning fluorescence nanoscope that simultaneously achieves superior resolution, a large field of view, and strong fluorescent signals. The acoustofluidic scanning fluorescence nanoscope utilizes the superresolution capabilities of microspheres that are controlled by a programmable acoustofluidic device for rapid fluorescence enhancement and imaging. The acoustofluidic scanning fluorescence …


Sleep, Eat, Repeat: An Examination Of The Influence Of Sleep And Biological Sex On Eating-Related Inhibitory Control In Overweight Emerging Adults, Shelby Mika Seipert-Raine May 2024

Sleep, Eat, Repeat: An Examination Of The Influence Of Sleep And Biological Sex On Eating-Related Inhibitory Control In Overweight Emerging Adults, Shelby Mika Seipert-Raine

Theses and Dissertations

Background: Lower inhibitory control has been shown to associate with greater risk for obesity in adolescence. On average, females have moderately higher rates of behavioral inhibitory control than males. These difference in inhibitory control across sex may influence overeating and development of obesity. This study examined whether sleep duration and sleep quality are associated with food-related inhibitory control and whether this association is moderated by biological sex. Methods: A total of 59 emerging adults ages 18 to 25 (37 males, 22 females) who had a BMI within the overweight or obese categories (BMI ≥25) completed self-report measures of eating and …


Neurobiological Underpinnings Of Autistic Traits, Sensory Processing, And Mental Health In Young Adult Males And Females, Miranda Jane Mcquarrie May 2024

Neurobiological Underpinnings Of Autistic Traits, Sensory Processing, And Mental Health In Young Adult Males And Females, Miranda Jane Mcquarrie

Theses and Dissertations

Females may present with autism more frequently than is diagnosed, due, in part, to autistic trait and sensory processing differences. Unfortunately, recruiting enough autistic female participants is difficult, because of such underdiagnoses. By approaching autism as a continuous variable, neurotypical (NT) individuals can be studied to better understand autistic individuals. Thus, to examine potential neurobiological underpinnings of sex-based behavioral profiles, we recruited 52 NT individuals (22 male; 30 female). Participants underwent resting-state functional magnetic resonance imaging (fMRI) to examine how functional network connectivity (via group independent components analysis) underpinned overall male/female differences in previously measured behavioral autistic trait and sensory …


Dissecting Trypanosome Metabolism By Discovering Glycolytic Inhibitors, Drug Targets, And Glycosomal Ph Regulation, Daniel Hale Call May 2024

Dissecting Trypanosome Metabolism By Discovering Glycolytic Inhibitors, Drug Targets, And Glycosomal Ph Regulation, Daniel Hale Call

Theses and Dissertations

Trypanosoma brucei, the causative agent of African trypanosomiasis, and its relatives Trypanosoma cruzi and several Leishmania species belong to a class of protozoa called kinetoplastids that cause a significant health burden in tropical and semitropical countries across the world. While an improved therapy was recently approved for African trypanosomiasis, the therapies available to treat infections caused by T. cruzi and Leishmania spp. remain relatively poor. Improving our understanding of T. brucei metabolism can inform on metabolism of its relatives. The purpose of the research presented in this dissertation was to develop novel tools and methods to study metabolism in T. …


Ionic Conductivity, Li+ Transference Number, And Diffusion Coefficient Of A Solid-State Electrolyte Composite, Lizbeth Zurita May 2024

Ionic Conductivity, Li+ Transference Number, And Diffusion Coefficient Of A Solid-State Electrolyte Composite, Lizbeth Zurita

Reviews, Analyses, and Instructional Studies in Electrochemistry (RAISE)

The design of solid-state electrolyte (SSE) composites involves the fundamental study of transport properties, such as ionic conductivity. This transport property is influenced by the transport mechanisms of the charge species inside the composite, such as diffusion and migration. In this work, we perform the measurement of these three parameters through defined techniques. The resulting parameters were: ionic conductivity, the diffusion coefficient, and the Li+ transference number.


Theory And Tools: The Future Of Technology-Based Learning (Script), Andrew S. Gibbons Iii May 2024

Theory And Tools: The Future Of Technology-Based Learning (Script), Andrew S. Gibbons Iii

Faculty Publications

We are entering a narrow passage that will see great instability in learning technology, instruction, and distance education. My purpose is to talk about two changes that I believe will redirect the entire future of technology-based education.


Theory And Tools: The Future Of Technology-Based Learning (Slides), Andrew S. Gibbons Iii May 2024

Theory And Tools: The Future Of Technology-Based Learning (Slides), Andrew S. Gibbons Iii

Faculty Publications

We are entering a narrow passage that will see great instability in learning technology, instruction, and distance education. My purpose is to talk about two changes that I believe will redirect the entire future of technology-based education.


Binding Interdependence: The Necessity Of Marriage In The Stonor Letters, Sarah Emmett Apr 2024

Binding Interdependence: The Necessity Of Marriage In The Stonor Letters, Sarah Emmett

The Thetean: A Student Journal for Scholarly Historical Writing

Upon her Mattiage to William Stonor in 1475, Elizabeth Stonor, nee Croke, was no wedding amateur. Twice before, she had stood on the steps of the church, as was the custom, and promised to share her wealth and her body with her husband. Twice before, her husband had promised to provide for her and leave her a dower portion upon his death. Both grooms had offered Elizabeth gold and silver coins and a ring to seal their union, and both times, Elizabeth and her husband had prostrated themselves before the altar of the church and heard mass among their family, …


Full Issue Apr 2024

Full Issue

The Thetean: A Student Journal for Scholarly Historical Writing

No abstract provided.


Changes In German Holocaust Memorials, Stephanie Bergeson Apr 2024

Changes In German Holocaust Memorials, Stephanie Bergeson

The Thetean: A Student Journal for Scholarly Historical Writing

Since World War II, Holocaust memorials have been built in many countries for a variety of reasons. Many memorials have been erected as places to remember and mourn the loss of those who were its victims. Some are built mainly to raise difficu lt but important moral and ethical questions in a world of increasing globalization and relativism. Others have been built to distance a country's association with the Holocaust and the Nazi government. Still others, as was the case with early Holocaust memorials in West Germany, were built in an attempt to forget or bury the past.


Sleep It Off? Exploring Sleep Duration And Bedtime Regularity As Potential Protective Moderators Of Early Adversity's Impact On Mental Health In Infancy, Childhood, And Adolescence, Sarah Lindsey Hipwell Kamhout Apr 2024

Sleep It Off? Exploring Sleep Duration And Bedtime Regularity As Potential Protective Moderators Of Early Adversity's Impact On Mental Health In Infancy, Childhood, And Adolescence, Sarah Lindsey Hipwell Kamhout

Theses and Dissertations

Introduction: Adverse Childhood Experiences (ACEs) are known to increase risk of mental health challenges throughout development, and sleep is known to decrease risk of mental health challenges. These have not been studied in tandem in younger cohorts. We investigated whether interactions between sleep duration and sleep regularity would moderate the impact of ACE exposure on risk for the development of mental health disorders. Methods: We conducted secondary cross-sectional analyses on the 2020-2021 waves of the National Survey of Children's Health (NSCH) (n = 92,669). We used logistic and ordinal regression to replicate known main effects of ACEs (total, household, community, …


The Effects Of Adverse And Positive Childhood Experiences On Childhood Mental Health And Behavior Problems, Jane Grace Smith Apr 2024

The Effects Of Adverse And Positive Childhood Experiences On Childhood Mental Health And Behavior Problems, Jane Grace Smith

Theses and Dissertations

Adverse childhood experiences (ACEs) are traumatic childhood events with enduring repercussions on child well-being, while positive childhood experiences (PCEs) have been identified in emerging research as capable of offsetting the effects of ACEs. However, little research investigates the combined impact of ACEs and PCEs on child outcomes, which can inform better aid for children exposed to ACEs. The purpose of this study is to address these important gaps in existing ACE literature. Using data from the National Survey of Child Health (NSCH) 2020-2021 (N = 60,809), I examine the individual and interactive effects of ACE, PCEs, and gender on childhood …


Lessening Lacunas: A Genetic Critique And Literary Analysis Of Female Indigenous Characters In Maria Firmina Dos Reis's Gupeva, Xana Furtado Apr 2024

Lessening Lacunas: A Genetic Critique And Literary Analysis Of Female Indigenous Characters In Maria Firmina Dos Reis's Gupeva, Xana Furtado

Theses and Dissertations

One year after publishing Úrsula (1860), Maria Firmina dos Reis (Brazil’s first female novelist) published Gupeva, a novella that acts as a continuation of José de Santa Rita Durão’s Caramurú: Poema épico do descubrimento da Bahia (1781). Gupeva depicts the ultimately tragic love between Épica, an indigenous woman, and Gastão, a French sailor. The novella was published twice more during Reis’s lifetime—once in 1863, with minimal orthographic changes, and again in 1865, this time with quite drastic modifications. The editors of Echo da Juventude, where the 1865 version was published, acknowledged these changes by asking readers to be "indulgentes para …