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The Pax-Six-Eya-Dach Network Modulates Gata-Fog Function In Fly Hematopoiesis And Human Erythropoiesis, T. Michael Creed, Rajkumar Baldeosingh, Christian L. Eberly, Caroline S. Schlee Jan 2020

The Pax-Six-Eya-Dach Network Modulates Gata-Fog Function In Fly Hematopoiesis And Human Erythropoiesis, T. Michael Creed, Rajkumar Baldeosingh, Christian L. Eberly, Caroline S. Schlee

Open Access archive

The GATA and PAX-SIX-EYA-DACH transcriptional networks (PSEDNs) are essential for proper development across taxa. Here, we demonstrate novel PSEDN roles in vivo in Drosophila hematopoiesis and in human erythropoiesis in vitro. Using Drosophila genetics, we show that PSEDN members function with GATA to block lamellocyte differentiation and maintain the prohemocyte pool. Overexpression of human SIX1 stimulated erythroid differentiation of human erythroleukemia TF1 cells and primary hematopoietic stem-progenitor cells. Conversely, SIX1 knockout impaired erythropoiesis in both cell types. SIX1 stimulation of erythropoiesis required GATA1, as SIX1 overexpression failed to drive erythroid phenotypes and gene expression patterns in GATA1 knockout cells. SIX1 …

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Multiclass Queueing Network Modeling And Traffic Flow Analysis For Sdn-Enabled Mobile Core Networks With Network Slicing, Santhosha Kamath, Sanjay Singh, M. Sathish Kumar Jan 2020

Multiclass Queueing Network Modeling And Traffic Flow Analysis For Sdn-Enabled Mobile Core Networks With Network Slicing, Santhosha Kamath, Sanjay Singh, M. Sathish Kumar

Open Access archive

The back-haul networks of 5G are formed by heterogeneous links which need to handle massive traffic. The service providers are not able to provide good QoS for their users. The technology like Software Defined Networks(SDN) and Network Slicing helps a little for a service provider to providing QoS for multiple links. The service providers face a challenge in the efficient utilization of resources to fulfill the QoS requirement of users to comply with the growth and thereby increasing the revenue. These problems require an accurate traffic model to determine the steady-state of the system. The proposed model uses an architecture …

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Mapping The Micro-Proteome Of The Nuclear Lamina And Lamina-Associated Domains, Xianrong Wong, Jevon A. Cutler, Victoria E. Hoskins, Molly Gordon Jan 2020

Mapping The Micro-Proteome Of The Nuclear Lamina And Lamina-Associated Domains, Xianrong Wong, Jevon A. Cutler, Victoria E. Hoskins, Molly Gordon

Open Access archive

The nuclear lamina is a proteinaceous network offilaments that provide both structural and gene regulatory functions by tethering proteins and large domains of DNA, the so-called lamina-associated domains (LADs), to the periphery of the nucleus. LADs are a large fraction of the mammalian genome that are repressed, in part, by their association to the nuclear periphery. The genesis and maintenance of LADs is poorly understood as are the proteins that participate in these functions. In an effort to identify proteins that reside at the nuclear periphery and potentially interact with LADs, we have taken a two-pronged approach. First, we have …

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Influence Of Stacking Sequence On The Mechanical Properties Of 3d E-Glass/Bamboo Non-Woven Hybrid Epoxy Composites, Suhas Yeshwant Nayak, B. Satish Shenoy, Mohamed Thariq Bin Hameed Sultan, Chandrakant R. Kini Jan 2020

Influence Of Stacking Sequence On The Mechanical Properties Of 3d E-Glass/Bamboo Non-Woven Hybrid Epoxy Composites, Suhas Yeshwant Nayak, B. Satish Shenoy, Mohamed Thariq Bin Hameed Sultan, Chandrakant R. Kini

Open Access archive

Hybridization of composites is one of the many ways to optimize cost, manufacturing process and strength required for a particular application. This demands a need for knowledge about the best possible ways to deal with the dissimilar materials in the composite system. Very little light has been shed about the stacking sequence implemented while dealing with non-woven natural fiber mats and 3D woven glass fiber fabric as reinforcement and effects of different models on the strength of composite - which has been dealt very vividly in this research work. Two types of hybrid stacking sequence were implemented using non-woven bamboo …

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Melioidosis In Suspected Recurrent Tuberculosis: A Disease In Disguise, Rahul Garg, Tushar Shaw, Kalwaje E. Vandana, Rahul Magazine Jan 2020

Melioidosis In Suspected Recurrent Tuberculosis: A Disease In Disguise, Rahul Garg, Tushar Shaw, Kalwaje E. Vandana, Rahul Magazine

Open Access archive

Introduction: Melioidosis, caused by the soil saprophyte B. pseudomallei, is a ‘neglected’ infectious disease in many Asian countries. It remained undiagnosed or misdiagnosed in India for long due to a lack of awareness and facilities to diagnose the disease; however, it is slowly gaining the status of an emerging disease recently. The disease is well known as a great mimicker, as the presentations are very similar to many other tropical diseases, and more importantly, to tuberculosis . Methodology: A prospective observational study was conducted from January 2016 – December 2018 to find the occurance of melioidosis in patients with ‘recurrent’ …

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Host Switching Events In Litomosoides Chandler, 1931 (Filarioidea: Onchocercidae) Are Not Rampant But Clade Dependent. Resulting Trees, F. Agustin Jimenez, Juliana Notarnicola Dr., Scott L. Gardner Dr. Jan 2020

Host Switching Events In Litomosoides Chandler, 1931 (Filarioidea: Onchocercidae) Are Not Rampant But Clade Dependent. Resulting Trees, F. Agustin Jimenez, Juliana Notarnicola Dr., Scott L. Gardner Dr.

Zoology Data Sets

Inlcudes a aligned datamatrix of 2 mitochondrial genes generated forfilarioid nematodes of the genus Litomosoides. Tree also includes phylogenetic trees generated with the use of Maximum Parsimony. Maximum Likelihood and estimation of the branch posterior probability (Bayesian statistics).

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Genome-Wide Sequence Analyses Of Ethnic Populations Across Russia, Daria V. Zhernakova, Vladimir Brukhin, Sergey Malov, Taras K. Oleksyk, Klaus Peter Koepfli, Anna Zhuk, Pavel Dobrynin, Sergei Kliver, Nikolay Cherkasov, Gaik Tamazian, Mikhail Rotkevich, Ksenia Krasheninnikova, Igor Evsyukov, Sviatoslav Sidorov, Anna Gorbunova, Ekaterina Chernyaeva, Andrey Shevchenko, Sofia Kolchanova, Alexei Komissarov, Serguei Simonov, Alexey Antonik, Anton Logachev, Dmitrii E. Polev, Olga A. Pavlova, Andrey S. Glotov, Vladimir Ulantsev, Ekaterina Noskova, Tatyana K. Davydova, Tatyana M. Sivtseva Jan 2020

Genome-Wide Sequence Analyses Of Ethnic Populations Across Russia, Daria V. Zhernakova, Vladimir Brukhin, Sergey Malov, Taras K. Oleksyk, Klaus Peter Koepfli, Anna Zhuk, Pavel Dobrynin, Sergei Kliver, Nikolay Cherkasov, Gaik Tamazian, Mikhail Rotkevich, Ksenia Krasheninnikova, Igor Evsyukov, Sviatoslav Sidorov, Anna Gorbunova, Ekaterina Chernyaeva, Andrey Shevchenko, Sofia Kolchanova, Alexei Komissarov, Serguei Simonov, Alexey Antonik, Anton Logachev, Dmitrii E. Polev, Olga A. Pavlova, Andrey S. Glotov, Vladimir Ulantsev, Ekaterina Noskova, Tatyana K. Davydova, Tatyana M. Sivtseva

Biology Faculty Articles

The Russian Federation is the largest and one of the most ethnically diverse countries in the world, however no centralized reference database of genetic variation exists to date. Such data are crucial for medical genetics and essential for studying population history. The Genome Russia Project aims at filling this gap by performing whole genome sequencing and analysis of peoples of the Russian Federation. Here we report the characterization of genome-wide variation of 264 healthy adults, including 60 newly sequenced samples. People of Russia carry known and novel genetic variants of adaptive, clinical and functional consequence that in many cases show …

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Knowledge Of, And Beliefs About, Access To Screening Facilities And Cervical Cancer Screening Behaviors Among Low-Income Women In New Jersey, Stephanie A.Navarro Silvera, Elisa V. Bandera, Beth A. Jones, Alejandra M. Kaplan, Kitaw Demisse Jan 2020

Knowledge Of, And Beliefs About, Access To Screening Facilities And Cervical Cancer Screening Behaviors Among Low-Income Women In New Jersey, Stephanie A.Navarro Silvera, Elisa V. Bandera, Beth A. Jones, Alejandra M. Kaplan, Kitaw Demisse

Department of Public Health Scholarship and Creative Works

Racial/ethnic disparities in cancer outcomes have been well documented. Access to Pap testing may account for some of the variation in the racial and socioeconomic differences in cervical cancer outcomes. Literature exploring perceived access to care as it relates to women of color and low-income women is lacking. The goal of the study was to evaluate and characterize the relationship between what respondents believe about access to free/low-cost screening facilities and screening behaviors among low-income women in New Jersey. We used multivariate logistic regression to investigate belief about access to affordable screening on cancer screening behaviors using data from a …

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Elucidating The Role Of Excision Repair Cross-Complement Group 1 In Oral Epithelial Dysplasia And Early Invasive Squamous Cell Carcinoma: An Immunohistochemical Study, Spoorti Kulkarni, Monica Solomon, Deepthi Pankaj, Sunitha Carnelio Jan 2020

Elucidating The Role Of Excision Repair Cross-Complement Group 1 In Oral Epithelial Dysplasia And Early Invasive Squamous Cell Carcinoma: An Immunohistochemical Study, Spoorti Kulkarni, Monica Solomon, Deepthi Pankaj, Sunitha Carnelio

Open Access archive

Objectives: Oral epithelial dysplasia (OED) is characterized by cellular alterations which have the proclivity of progressing to squamous cell carcinoma. Excision repair cross-complement group 1 (ERCC1) is one of the key proteins involved in nucleotide excision repair (NER) pathway. The expression of ERCC1 has been studied in colorectal, esophageal, ovarian and oral squamous cell carcinoma; but, very few studies have been done to apprehend the expression of ERCC1 in OED and early invasive squamous cell carcinoma (EISCC). The goal of this study is to evaluate the role of ERCC1 in OED and EISCC. Materials and Methods: Histopathologically diagnosed cases of …

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The Impact Of Lifestyles On Dental Caries Of Adult Patients In Udupi District: A Cross-Sectional Study, Nishu Singla, Shashidhar Acharya, Ritesh Singla, Prajna Nayak Jan 2020

The Impact Of Lifestyles On Dental Caries Of Adult Patients In Udupi District: A Cross-Sectional Study, Nishu Singla, Shashidhar Acharya, Ritesh Singla, Prajna Nayak

Open Access archive

Background: Dental caries is preventable if favorable health behavior is successfully established. Exploring the broader concept of lifestyle will be useful to determine that how lifestyle of people can affect dental caries. Aim: The aim of this study was to determine the impact of overall lifestyle of an individual (analyzed using health practice index) on dental caries of adult population. Material and Methods: This cross-sectional study comprising structured questions on health practice index, sociodemographic variables, and oral health-related behavior was conducted on 800 study subjects of age 20-50 years attending outreach dental setups of a dental school in India. Dental …

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Educating Girls, Educated Women: Dehomogenizing The Impact Of Education In Development, Tricia Beck-Peter, Nikolai G. Wenzel Jan 2020

Educating Girls, Educated Women: Dehomogenizing The Impact Of Education In Development, Tricia Beck-Peter, Nikolai G. Wenzel

College of Business and Economics

After a half-century of failed top-down international aid efforts that ignore basic microeconomics, the New Development Economics (NDE) offers an alternative. First, sound institutions (such as rule of law, property rights, contractual enforcement, etc.); second, respect for basic microeconomic principles (from incentives to knowledge). Within the New Development Economics, development economist William Easterly offers controversial and innovative insights; one of these is the ineffectiveness of education-alone, and without sound institutions-for promoting growth. We argue that Easterly is generally correct, but we improve on Easterly's lessons by dehomogenizing education. Specifically, education for girls has high marginal returns: at the micro level, …

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Aquatic Habitat Changes Along The Arkansas River (Supporting Data And Code), Mike Rhodes, Jonathan Spurgeon, Wes Neal, Kristine Evans Jan 2020

Aquatic Habitat Changes Along The Arkansas River (Supporting Data And Code), Mike Rhodes, Jonathan Spurgeon, Wes Neal, Kristine Evans

CFR Publications

The associated code and data are supporting information for an assessment of large-scale changes in aquatic habitats within the varying pools of the Arkansas River, Arkansas, USA following impoundment of the river as part of the McClellan–Kerr Arkansas River Navigation System. We used a combination of Landsat satellite data (30 m resolution) from 1984-2016 and the European Commission Joint Research Center’s (JRC) Global Surface Water dataset (GSW) to assess changes in water availability by aquatic habitat category and river pool in the Arkansas River system. Analysis was completed using Google Earth Engine, with code available in this repository. We also …

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Aquatic Habitat Changes Along The Arkansas River (Supporting Data For Analysis), Jonathan Spurgeon, Mike Rhodes, Wes Neal, Kristine Evans Jan 2020

Aquatic Habitat Changes Along The Arkansas River (Supporting Data For Analysis), Jonathan Spurgeon, Mike Rhodes, Wes Neal, Kristine Evans

CFR Publications

The associated code and data represent a second set of supporting information for an assessment of large-scale changes in aquatic habitats within the varying pools of the Arkansas River, Arkansas, USA following impoundment of the river as part of the McClellan–Kerr Arkansas River Navigation System. We used a combination of Landsat satellite data (30 m resolution) from 1984-2016 and the European Commission Joint Research Center’s (JRC) Global Surface Water dataset (GSW) to assess changes in water availability by aquatic habitat category and river pool in the Arkansas River system. Here we provide compiled .csv files of Arkansas River gauge data, …

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Species Distribution Models To Inform At-Risk Species Status Assessments In The Southeastern Us, Carlos Ramirez-Reyes, Mona Nazeri, Garrett Street, Francisco Vilella, D. Todd Jones-Farrand, Kristine O. Evans Jan 2020

Species Distribution Models To Inform At-Risk Species Status Assessments In The Southeastern Us, Carlos Ramirez-Reyes, Mona Nazeri, Garrett Street, Francisco Vilella, D. Todd Jones-Farrand, Kristine O. Evans

CFR Publications

The USFWS is working collaboratively with State Wildlife Agencies, Universities, Non-profits and others in the southeast to address the National Listing Workplan. The USFWS needs up-to-date information on current status and the likely impact of future changes to develop Species Status Assessments (SSAs), which help inform listing decisions. States, Universities and other partners are providing species expertise, location data, analytical support and logistical support (e.g. surveys). However, a significant knowledge gap remains in understanding potential species distributions, from which status surveys can be more strategically implemented. This project provides a bridge between species location information and the SSAs by developing …

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Recreating A Classical Sleeping Beauty Tutu And Bodice Using Modern Methods, Gennevieve L. Wright Jan 2020

Recreating A Classical Sleeping Beauty Tutu And Bodice Using Modern Methods, Gennevieve L. Wright

Honors College Theses

Tchaikovsky’s ballet Sleeping Beauty was first produced in the Mariinsky Theatre in St. Petersburg on January 15, 1890. Since the ballet’s debut, the design and construction of the leading tutus have evolved and spread considerably. In most modern renditions of this particular ballet, the silhouette of the tutu includes a skirt made of net tulle that sticks straight out from either the hip or the waist, depending on the exact style. This silhouette that is so integral to a majority of modern ballets did not appear until the 1870s, just twenty short years before Sleeping Beauty’s debut. This project will …

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Childish: An Original Screenplay, Sally Rubin Jan 2020

Childish: An Original Screenplay, Sally Rubin

Renée Crown University Honors Thesis Projects - All

No abstract provided.

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Essential Oils Of Tagetes Minuta And Tithonia Diversifolia Affect Host Location Behaviour And On-Host Attachment Site Preference Of The Brown Ear Tick, Rhipicephalus Appendiculatus In The Semi-Field Studies, Wycliffe Wanzala, Ahmed Hassanali, Wolfgang Richard Mukabana, Willem Takken, Sheila Iminza Minyoso Jan 2020

Essential Oils Of Tagetes Minuta And Tithonia Diversifolia Affect Host Location Behaviour And On-Host Attachment Site Preference Of The Brown Ear Tick, Rhipicephalus Appendiculatus In The Semi-Field Studies, Wycliffe Wanzala, Ahmed Hassanali, Wolfgang Richard Mukabana, Willem Takken, Sheila Iminza Minyoso

All Peer-Reviewed Publications

Effects of essential oils of Tagetes minuta and Tithonia diversifolia (Asteraceae) on orientation behaviour and on-host attachment site preference of newly hatched adult Rhipicephalus appendiculatus were evaluated. Host animals were treated at the ear pinna (by smearing the oil directly on the ear or suspending a tube containing the oil on the ear pinna) and legs + tail in semi-field plots. The legs + tail sites of the essential oil application showed the lowest mean percentage of ticks observed on host body (16.5 ± 1.9% and 26.0 ± 2.8%) and the highest mean percentage reduction of attaching ticks (76.5 ± …

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Mineral Fertilizer Use In Land-Scarce Conditions: Case Of Rwanda, Josaphat Rusisiro Mugabo, Eric Tollens, Jonas Nwankwo Chianu, Bernard Vanlauwe Jan 2020

Mineral Fertilizer Use In Land-Scarce Conditions: Case Of Rwanda, Josaphat Rusisiro Mugabo, Eric Tollens, Jonas Nwankwo Chianu, Bernard Vanlauwe

All Peer-Reviewed Publications

This study was undertaken to investigate the use of mineral fertilizer by smallholder farmers in order to understand the set of factors influencing the decisions of smallholder farmers to use fertilizers in land-scarce conditions. Using descriptive analysis and the Cragg's double-hurdle model, the study identified and analyzed factors that determine smallholder farmer adoption of mineral fertilizers and those that affect the intensity of household mineral fertilizer use. From factors that only influence the decision of smallholder farmers to use mineral fertilizers, distance to fertilizer market and livestock affects it negatively; while farmer association membership, landholding per capita, access to extension …

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Population Genetics Of The Mediterranean Corn Borer (Sesamia Nonagrioides) Differs Between Wild And Cultivated Plants, Abdel Kader Naino Jika, B. Le Ru, C. Capdevielle-Dulac, F. Chardonnet, J. F. Silvain, L. Kaiser, S. Dupas Jan 2020

Population Genetics Of The Mediterranean Corn Borer (Sesamia Nonagrioides) Differs Between Wild And Cultivated Plants, Abdel Kader Naino Jika, B. Le Ru, C. Capdevielle-Dulac, F. Chardonnet, J. F. Silvain, L. Kaiser, S. Dupas

All Peer-Reviewed Publications

The population genetic structure of crop pest populations gives information about their spatial ecology, which helps in designing management strategies. In this paper, we investigated the genetic structure of the Mediterranean Corn Borer (MCB), Sesamia nonagrioides Lefèbvre (Lepidoptera: Noctuidae), one of the most important maize pests in the Mediterranean countries, using microsatellite markers for the first time in this species. Insects were collected in twenty-five locations in southwest and southeast France from cultivated and wild host plants (Zea mays, Sorghum halepense and Typha domingensis). Contrary to what has been reported so far in France, we found that MCB populations could …

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Communication Through Creative Drama In Architectural Education: Example Of Basic Design Course, Hare Kılıçaslan Jan 2020

Communication Through Creative Drama In Architectural Education: Example Of Basic Design Course, Hare Kılıçaslan

Khazar Journal of Humanities and Social Sciences

Man lives in a physical and social environment. It is necessary to be open to all communication in the classroom environment for ensuring an effective learning process. Since the number of students has been increased in recent years, it was inevitable to use different methods in education. It is inevitable to enable the interaction between teacher and teacher, teacher, and learner as well as the interaction between learner and learner. In addition, it is necessary to establish learning environments based on the exchange of information and ideas alongside the intellectual and experiential activities based on communication. Since the creative drama …

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Performance Enhancement And Prediction Of Composite Materials With Embedded Electrospun Piezoelectric Sensors, Rahman Jani Mazed, Muthu Ram Prabhu Elenchezhian, Vamsee Vadlamudi, Md Riaz Uddin Ahmed, Rassel Raihan, Kenneth Reifsnider Jan 2020

Performance Enhancement And Prediction Of Composite Materials With Embedded Electrospun Piezoelectric Sensors, Rahman Jani Mazed, Muthu Ram Prabhu Elenchezhian, Vamsee Vadlamudi, Md Riaz Uddin Ahmed, Rassel Raihan, Kenneth Reifsnider

Institute of Predictive Performance Methodologies (IPPM-UTARI)-Archive

In today’s world, continuous fiber reinforced composite materials are extensively used in the aerospace, automotive and other structural industries. Since the applications of such fibers demand for a high safety rating, it is of utmost importance for engineers who design such materials to analyze its safety. When cracks are developed in such materials, the mechanical, electrical, and thermal properties also get altered as a function of the cracks. Previous studies have shown that changes in electrical properties can be directly correlated with the development of cracks in the material which can then be used to predict the remaining life of …

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Near Full Thickness Macular Hole With An Intact Overlying Internal Limiting Membrane Following Resolution Of Fulminant Acquired Toxoplasma Retinitis -A Unique Finding, Kalpana Babu, Dhwani Shah, M. Bhagya, Krishna Murthy Jan 2020

Near Full Thickness Macular Hole With An Intact Overlying Internal Limiting Membrane Following Resolution Of Fulminant Acquired Toxoplasma Retinitis -A Unique Finding, Kalpana Babu, Dhwani Shah, M. Bhagya, Krishna Murthy

Open Access archive

A 43-year-old immunocompetent male presented with focal macular retinitis with overlying vitritis in the right eye. His BCVA was counting fingers close to face. OCT showed increased intraretinal thickness at the area of retinitis with adjacent hypo reflectivity of the choroid. Serology was positive for IgM and IgG antibodies for toxoplasma. He received oral clindamycin 300 mg 4 times/day for 8 weeks. At 6 weeks, his BCVA was CF 2 metres. Fundus showed complete resolution of retinitis with formation of near, full thickness macular hole with intact overlying ILM. A small hyper reflective scar was seen at the base of …

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Rough Set Based Qos Enabled Multipath Source Routing In Manet, N. Prathviraj, Santosh L. Deshpande Jan 2020

Rough Set Based Qos Enabled Multipath Source Routing In Manet, N. Prathviraj, Santosh L. Deshpande

Open Access archive

The single constrained Quality of Service (QoS) routing in Mobile Ad-hoc NETwork (MANET) is disastrous in consideration of MANET characteristics, inference, collision and link failure as it maintains a single path. The QoS enabled routing yields better packet delivery and maintains consistency among nodes in the network by incorporating multi-constrained and multipath routing. The Dynamic Source Routing (DSR) is best suited source routing algorithm to maintain multipath information at the source node, but performance degrades with larger number of mobile nodes. Multi-layer mechanism should be incorporated to maintain QoS metric information spreads across multiple layers of TCP/IP protocol stack. The …

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Surface Topographical Studies Of Glass Fiber Reinforced Epoxy-Zno Nanocomposites, Sridhar Thipperudrappa, Achutha Ullal Kini, Anupama Hiremath, Karani Dileep Kumar Jan 2020

Surface Topographical Studies Of Glass Fiber Reinforced Epoxy-Zno Nanocomposites, Sridhar Thipperudrappa, Achutha Ullal Kini, Anupama Hiremath, Karani Dileep Kumar

Open Access archive

The objective of present research work is to investigate the surface morphology and surface microhardness of unidirectional E-glass fiber epoxy composites filled with varying amount of ZnO nanofiller content such as 1, 2, 3, 4 and 5 wt% respectively. ZnO nanofiller was added to the epoxy resin matrix in varying amount (wt%) using mechanical stirrer and followed by ultrasonication process. The laminate composites were fabricated using a compression molding press technique. Further, laminate composites were subjected to individual characterization and testing according to ASTM standards. The crystalline nature of ZnO nanofiller was studied using x-ray diffraction analysis (XRD) and surface …

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Effect Of Thermocycling On The Colour Stability Of Aesthetic Restorative Materials: An In-Vitro Spectrophotometric Analysis, Swastika Bhattacharya, Tina Puthen Purayil, Kishore Ginjupalli, Sandya Kini Jan 2020

Effect Of Thermocycling On The Colour Stability Of Aesthetic Restorative Materials: An In-Vitro Spectrophotometric Analysis, Swastika Bhattacharya, Tina Puthen Purayil, Kishore Ginjupalli, Sandya Kini

Open Access archive

Objective: To compare the color stability of Cention N, Fuji IX GP Extra, and Fuji IX GP after thermocycling. Material and Methods: Ten discs of each material of dimension 10 x 1 mm were prepared using a split mold. The preparations of the specimens were done according to the powder/liquid ratio as recommended by the manufacturers [4.6:1, 3.4:1 and 3.6:1 for the groups I, II, and III respectively]. After setting, the samples were retrieved, and the thickness of each specimen was measured using a micrometer at five different locations. The specimens with variations in thickness, porosity or cracks were discarded …

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Diagnostic Accuracy Of Mri For Traumatic Adult Brachial Plexus Injury: A Comparison Study With Surgical Findings, A. M. Acharya, Blessin S. Cherian, Anil K. Bhat Jan 2020

Diagnostic Accuracy Of Mri For Traumatic Adult Brachial Plexus Injury: A Comparison Study With Surgical Findings, A. M. Acharya, Blessin S. Cherian, Anil K. Bhat

Open Access archive

We studied the diagnostic accuracy of MRI in 35 adult patients with traumatic brachial plexus injury in comparison with intra operative findings. The overall sensitivity to detect root avulsions was 39% and specificity was 75%. MRI was more useful in the diagnosis of lower root avulsions. At trunk and division level injuries, the sensitivity was 87% but specificity was only 26%. It was not able to differentiate the type and extent of post-ganglionic injuries. The accuracy of pseudomeningocele as avulsion on surgical finding was 96% (27/28). Pseudomeningocele correlates well with root avulsions. Its presence warrants early referral and surgical exploration.

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Structure-Function Relationship Of H2a-H2b Specific Plant Histone Chaperones, Ashish Kumar, Dileep Vasudevan Jan 2020

Structure-Function Relationship Of H2a-H2b Specific Plant Histone Chaperones, Ashish Kumar, Dileep Vasudevan

Open Access archive

Studies on chromatin structure and function have gained a revived popularity. Histone chaperones are significant players in chromatin organization. They play a significant role in vital nuclear functions like transcription, DNA replication, DNA repair, DNA recombination, and epigenetic regulation, primarily by aiding processes such as histone shuttling and nucleosome assembly/disassembly. Like the other eukaryotes, plants also have a highly orchestrated and dynamic chromatin organization. Plants seem to have more isoforms within the same family of histone chaperones, as compared with other organisms. As some of these are specific to plants, they must have evolved to perform functions unique to plants. …

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Multiple Intrusion Detection In Rpl Based Networks, Manjula C. Belavagi, Balachandra Muniyal Jan 2020

Multiple Intrusion Detection In Rpl Based Networks, Manjula C. Belavagi, Balachandra Muniyal

Open Access archive

Routing Protocol for Low Power and Lossy Networks based networks consists of large number of tiny sensor nodes with limited resources. These nodes are directly connected to the Internet through the border router. Hence these nodes are susceptible to different types of attacks. The possible attacks are rank attack, selective forwarding, worm hole and Denial of service attack. These attacks can be effectively identified by intrusion detection system model. The paper focuses on identification of multiple intrusions by considering the network size as 10, 40 and 100 nodes and adding 10%, 20% and 30% of malicious nodes to the considered …

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Neuroprotective Effects Of Resveratrol In Alzheimer's Disease, Yelluru Lakshmisha Rao, Bolumbu Ganaraja, Teresa Joy, Mangala M. Pai Jan 2020

Neuroprotective Effects Of Resveratrol In Alzheimer's Disease, Yelluru Lakshmisha Rao, Bolumbu Ganaraja, Teresa Joy, Mangala M. Pai

Open Access archive

Alzheimer's disease (AD) is a neurodegenerative disorder, which is commonly seen in older individuals. This is characterized by cognitive dysfunction, which leads to dementia. Pharmacological treatments for AD are mainly targeted on its symptoms like memory loss and cognitive impairment. The pathophysiology involved in AD is intra-neuronal accumulation of hyper-phosphorylated tau protein as neurofibrillary tangle and extra cellular beta amyloid plaque deposition, which is due to oxidative stress. Here we review the neuro-protective effects of Resveratrol (RSV) and its treatment efficacy in AD. RSV is a naturally available polyphenolic compound, which has antioxidant, anti-cancerous, anti-inflammatory and anti-aging properties. RSV crosses …

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Epithelial To Mesenchymal Plasticity: Role In Cancer Progression, Remya Raja, Akhilesh Pandey, Prashant Kumar Jan 2020

Epithelial To Mesenchymal Plasticity: Role In Cancer Progression, Remya Raja, Akhilesh Pandey, Prashant Kumar

Open Access archive

Epithelial-mesenchymal transition (EMT) is a dynamic process by which the cells transdifferentiate into two or more somatic states. The metastatic spread begins with tumor cells disseminated from the primary tumor via intravasation, hematogenous transit and extravasation to reach the distant organs to form micro- or macrometastasis. Dissemination of tumor cells or metastasis is a crucial stage in cancer progression and accounts for majority of cancer associated morbidity and mortality. Advances in technology has now enabled detection and capture of tumor cells that escape from primary site into the bloodstream. Such tumor cells which are found in transit in the blood …

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