Digital Commons Network^™

A Quantitative Validation Of Segmented Colon In Virtual Colonoscopy Using Image Moments, K. N. Manjunath, G. K. Prabhu, P. C. Siddalingaswamy

Open Access archive

Background: Evaluation of segmented colon is one of the challenges in Computed Tomography Colonography (CTC). The objective of the study was to measure the segmented colon accurately using image processing techniques. Methods: This was a retrospective study, and the Institutional Ethical clearance was obtained for the secondary dataset. The technique was tested on 85 CTC dataset. The CTC dataset of 100–120 kVp, 100 mA, and ST (Slice Thickness) of 1.25 and 2.5 mm were used for empirical testing. The initial results of the work appear in the conference proceedings. Post colon segmentation, three distance measurement techniques, and one volumetric overlap …

Reply To: Formatting References For Scientific Manuscripts, B. V. Murlimanju, Latha V. Prabhu, Mangala M. Pai

Open Access archive

No abstract provided.

Bioinformatics Analysis Of Global Proteomic And Phosphoproteomic Data Sets Revealed Activation Of Nek2 And Aurka In Cancers, Barnali Deb, Pratyay Sengupta, Janani Sambath, Prashant Kumar

Open Access archive

Tumor heterogeneity attributes substantial challenges in determining the treatment regimen. Along with the conventional treatment, such as chemotherapy and radiotherapy, targeted therapy has greater impact in cancer management. Owing to the recent advancements in proteomics, we aimed to mine and re-interrogate the Clinical Proteomic Tumor Analysis Consortium (CPTAC) data sets which contain deep scale, mass spectrometry (MS)-based proteomic and phosphoproteomic data sets conducted on human tumor samples. Quantitative proteomic and phosphoproteomic data sets of tumor samples were explored and downloaded from the CPTAC database for six different cancers types (breast cancer, clear cell renal cell carcinoma (CCRCC), colon cancer, lung …

Advanced Microscopy Techniques For Revealing Molecular Structure Of Starch Granules, Ishita Chakraborty, Sparsha Pallen, Yuthika Shetty, Niranjana Roy

Open Access archive

Starch is a major source of our daily diet and it is important to understand the molecular structure that plays a significant role in its wide number of applications. In this review article, microscopic structures of starch granules from potato, corn, rice canna, tania, wheat, sweet potato, and cassava are revealed using advanced microscopic techniques. Optical microscopy depicts the size and shape, polarization microscopy shows the anisotropy properties of starch granules, scanning electron microscopy (SEM) displays surface topography, and confocal microscopy is used to observe the three-dimensional internal structure of starch granules. The crystallinity of starch granules is revealed by …

Metal-Decorated Carbon Nanotubes For Gas Sensing Applications, Icell Sharafeldin

Theses and Dissertations

This thesis reports on the investigation of metal-decorated carbon nanotubes-based sensor arrays with enhanced sensitivity and selectivity toward toxic gases. Ab initio first-principles methods were used to expedite the process of identifying the right materials with the highest potential compared to in-lab trial and error as well as to provide a deeper understanding of the gas adsorption mechanism. The mechanism of NO2 adsorption on Cu-, Pt- and Ti-doped single-walled carbon nanotubes (SWCNTs) was investigated. Modelling the isolated NO2 molecule indicated the formation of a band gap between the 3Ï€* HOMO and 5σ* LUMO levels, which were found to be the …

Studies On Guest/Host Complexes, Liposomal And Other Systems For Potential Chemotherapeutic Drug(S) Delivery, Sherif Ashraf Fahmy

Theses and Dissertations

Following the discovery of cisplatin over 50 years ago, this platinum-based drug (PBD) has been a widely used and effective form of cancer therapy, primarily causing cell death by inducing DNA damage and triggering apoptosis. However, the dose limiting toxicity of cisplatin has led to the development of the newer generations' platinum-based drugs (second and third) that maintain the cytotoxicity of cisplatin but have more acceptable side-effect profiles. In addition to the creation of new analogs, tumor delivery systems such as liposome-encapsulated platinum drugs have been designed and are currently in clinical trials. In this study, we have created and …

Plant Community Composition And Functional Characteristics Define Invasion And Infestation Of Termites In Cocoa Agroforestry Systems, T. C.L. Djuideu, D. H.B. Bisseleua, S. Kekeunou, M. J. Meupia, F. G. Difouo, C. F. Ambele

All Peer-Reviewed Publications

The effects of farm management on non-native species and the structure and function of native communities and ecosystems on crop yield is poorly documented especially in the cocoa agroforestry systems of West Africa. We assessed termite damages, cocoa plantations structural characteristic and local farmer knowledge to refine the critical role of shade trees management on subterranean crops pests and the consequences on marketable yield in five cocoa agroforestry systems. Farmers recognized termites as the most damaging subterranean pests and clearly described the type of damages they cause on cocoa trees and seedlings. Complete shade removal or very heavy shade on …

High Risk For Human Exposure To Rift Valley Fever Virus In Communities Living Along Livestock Movement Routes: A Cross-Sectional Survey In Kenya, Caroline Tigoi, Rosemary Sang, Edith Chepkorir, Benedict Orindi, Samuel Okello Arum, Francis Mulwa, Gladys Mosomtai, Samson Limbaso, Osama A. Hassan, Zephania Irura, Clas Ahlm, Magnus Evander

All Peer-Reviewed Publications

Introduction Multiple outbreaks of Rift Valley Fever (RVF) with devastating effects have occurred in East Africa. These outbreaks cause disease in both livestock and humans and affect poor households most severely. Communities living in areas practicing nomadic livestock movement may be at higher risk of infection. This study sought to i) determine the human exposure to Rift Valley fever virus (RVFV) in populations living within nomadic animal movement routes in Kenya; and ii) identify risk factors for RVFV infection in these communities. Methods A cross-sectional descriptive study design was used. Samples were collected from the year 2014 to 2015 in …

Modelling And Manipulation Of Aphid-Mediated Spread Of Non-Persistently Transmitted Viruses, John P. Carr, Trisna Tungadi, Ruairí Donnelly, Ana Bravo-Cazar, Sun Ju Rhee, Lewis G. Watt, J. Musembi Mutuku, Francis O. Wamonje, Alex M. Murphy, Warren Arinaitwe, Adrienne E. Pate, Nik J. Cunniffe, Christopher A. Gilligan

All Peer-Reviewed Publications

Aphids vector many plant viruses in a non-persistent manner i.e., virus particles bind loosely to the insect mouthparts (stylet). This means that acquisition of virus particles from infected plants, and inoculation of uninfected plants by viruliferous aphids, are rapid processes that require only brief probes of the plant's epidermal cells. Virus infection alters plant biochemistry, which causes changes in emission of volatile organic compounds and altered accumulation of nutrients and defence compounds in host tissues. These virus-induced biochemical changes can influence the migration, settling and feeding behaviours of aphids. Working mainly with cucumber mosaic virus and several potyviruses, a number …

Transformations To Sustainability: Combining Structural, Systemic And Enabling Approaches, Ian Scoones, Andrew Stirling, Dinesh Abrol, Joanes Atela, Lakshmi Charli-Joseph, Hallie Eakin, Adrian Ely, Per Olsson, Laura Pereira, Ritu Priya, Patrick Van Zwanenberg, Lichao Yang

All Peer-Reviewed Publications

The imperatives of environmental sustainability, poverty alleviation and social justice (partially codified in the Sustainable Development Goals or SDGs) call for ambitious societal transformations. As such, few aspects of actionable knowledge for sustainability are more crucial than those concerning the processes of transformation. This article offers a brief overview of different conceptualisations of transformation, and outlines a set of practical principles for effective research and action towards sustainability. We review three approaches to transformations, labelled: ‘structural’, ‘systemic’ and ‘enabling’. We show how different ways of understanding what we mean by transformations can affect what actions follow. But these approaches are …

Recurrent Ttn Metatranscript‐Only C.39974–11t>G Splice Variant Associated With Autosomal Recessive Arthrogryposis Multiplex Congenita And Myopathy, Sj Bryen, Lj Ewans, J Pinner, Et Al

Peninsula Medical School

We present eight families with arthrogryposis multiplex congenita and myopathy bearing a TTN intron 213 extended splice-site variant (NM_001267550.1:c.39974-11T>G), inherited in trans with a second pathogenic TTN variant. Muscle-derived RNA studies of three individuals confirmed mis-splicing induced by the c.39974-11T>G variant; in-frame exon 214 skipping or use of a cryptic 3' splice-site effecting a frameshift. Confounding interpretation of pathogenicity is the absence of exons 213-217 within the described skeletal muscle TTN N2A isoform. However, RNA-sequencing from 365 adult human gastrocnemius samples revealed that 56% specimens predominantly include exons 213-217 in TTN transcripts (inclusion rate ≥66%). Further, RNA-sequencing of …

Modelling The Effects Of Slip On Dipole/Wall Collision Problems Using A Lattice Boltzmann Equation Method, S Mohammed, T Reis, D Graham

School of Engineering, Computing and Mathematics

We study the physics of flow due to the interaction between a viscous dipole and boundaries that permit slip. This includes partial and free slip, and interactions near corners. The problem is investigated by using a two relaxation time lattice Boltzmann equation with moment-based boundary conditions. Navier-slip conditions, which involve gradients of the velocity, are formulated and applied locally. The implementation of free-slip conditions with the moment-based approach is discussed. Collision angles of 0°, 30°, and 45° are investigated. Stable simulations are shown for Reynolds numbers between 625 and 10 000 and various slip lengths. Vorticity generation on the wall …

Internalized Sexual Stigma As Internal Minority Stress: The Egyptian Gay Experience, Hani Momtaz Henry

Faculty Journal Articles

No abstract provided.

Special Issue: The Political Aesthetics Of Democratization Conflicts, Marco Pinfari

Faculty Journal Articles

No abstract provided.

Fabrication Of Nanofibrous/Xerogel Layer-By-Layer Biocomposite Scaffolds For Skin Tissue Regeneration: In Vitro Study, Fatma Elshishiny, Wael Mamdouh Sayed Ahmed

Faculty Journal Articles

Skin burn wounds are a crucial issue that could reduce life quality. Although numerous effective skin products have invaded the biomedical market, most of them still demonstrate some limitations regarding their porosity, swelling and degradation behaviors, antibacterial properties, and cytotoxicity. Thus, the aim of this study is to fabricate novel trilayered asymmetric porous scaffolds that can mimic the natural skin layers. In particular, the fabricated scaffold constitutes an upper electrospun chitosan-poly(vinyl alcohol) layer and a lower xerogel layer, which is made of effective skin extracellular matrix components. Both layers are fixed together using fibrin glue as a middle layer. The …

Different Plant Viruses Induce Changes In Feeding Behavior Of Specialist And Generalist Aphids On Common Bean That Are Likely To Enhance Virus Transmission, Francis O. Wamonje, Ruairí Donnelly, Trisna D. Tungadi, Alex M. Murphy, Adrienne E. Pate, Christine Woodcock, John Caulfield, J. Musembi Mutuku, Toby J.A. Bruce, Christopher A. Gilligan, John A. Pickett, John P. Carr

All Peer-Reviewed Publications

Bean common mosaic virus (BCMV), bean common mosaic necrosis virus (BCMNV), and cucumber mosaic virus (CMV) cause serious epidemics in common bean (Phaseolus vulgaris), a vital food security crop in many low-to-medium income countries, particularly in Sub-Saharan Africa. Aphids transmit these viruses “non-persistently,” i.e., virions attach loosely to the insects' stylets. Viruses may manipulate aphid-host interactions to enhance transmission. We used direct observation and electrical penetration graph measurements to see if the three viruses induced similar or distinct changes in feeding behaviors of two aphid species, Aphis fabae and Myzus persicae. Both aphids vector BCMV, BCMNV, and CMV but A. …

The Role Of Dynamic Mirisc During Neuronal Development, Bharti Nawalpuri, Sreenath Ravindran, Ravi S. Muddashetty

Open Access archive

Activity-dependent protein synthesis plays an important role during neuronal development by fine-tuning the formation and function of neuronal circuits. Recent studies have shown that miRNAs are integral to this regulation because of their ability to control protein synthesis in a rapid, specific and potentially reversible manner. miRNA mediated regulation is a multistep process that involves inhibition of translation before degradation of targeted mRNA, which provides the possibility to store and reverse the inhibition at multiple stages. This flexibility is primarily thought to be derived from the composition of miRNA induced silencing complex (miRISC). AGO2 is likely the only obligatory component …

A Comparison Of Common Health Indicators From Two Surveys Of Latinos In The Bronx, New York, Aldo Crossa, Jillian Jessup, Sze Yan Liu, Carmen R, Isasi, David B. Hanna, Simin Hua, Fangtao He, Amber Levanon Seligson, Sungwoo Lim

Department of Public Health Scholarship and Creative Works

Introduction:

Population health surveys inform and demonstrate the impact of public health policies. However, the performance of such surveys in specific groups of interest (e.g., Hispanics/Latinos in a neighborhood of New York City) is rarely studied.

Method:

We compared measures for obesity, hypertension, diabetes, and current smoking based on the New York City Community Health Survey (CHS, a telephone survey of New York City adults) with the Hispanic Community Health Survey/Study of Latinos (HCHS/SOL), an in-person survey of Hispanic/Latino adults in four communities in the United States (2008-2011), including the Bronx. CHS data were limited to Hispanic/Latinos living in the …

Documents From The January 29, 2020 Meeting Of The Associated Students Of The University Of Montana (Asum), University Of Montana--Missoula. Associated Students

Senate Meeting Agendas and Minutes, 2007-Present

Agenda and meeting minutes from the January 29, 2020 meeting of the Associated Students of the University of Montana (ASUM). The following resolutions were discussed during the meeting:

SB46-19/20: Resolution Adjusting Student Employee Hours to Reflect a Biweekly Pay Period

SB51-19/20: Resolution Amending Referendum Language for Article 4 of the ASUM Constitution

SB52-19/20: Resolution Regarding Referendum Language for Article 6 of the ASUM Constitution

SB53-19/20: Resolution Amending Article V, Section 27 of the ASUM Bylaws

How Two Psychology Professors Earned $6 Million To Support Chicago Youth At Risk Of Violence, University Marketing And Communications, Lavome Robinson, Leonard Jason

DePaul Download

No abstract provided.

Export Of Peter Taylor's Website, Peter John Taylor

Curriculum and Instruction Faculty Publication Series

The attached file is an export of Peter Taylor's website from January 28, 2020. Peter Taylor passed away on October 29, 2019.

To access the archived version of Professor Taylor's website, download and export the zipped/compressed file, and click on the "index.html" file in the folder "peter-taylor-website."

Cosm-Nutraceutical Nanovesicles For Acne Treatment: Physicochemical Characterization And Exploratory Clinical Experimentation, Sandra Sherif Amer, Wael Mamdouh Sayed Ahmed

Faculty Journal Articles

The full exploration of the ‘nutraceuticals’ therapeutic potential in cosmetics has been hindered by their poor stratum corneum permeation. Therefore, the aim of the present study was to formulate a nutraceutical; quercetin, in novel vitamin C based nanovesicles (aspasomes), and to explore their beneficial effects in the treatment of acne. Aspasomes were characterized for their particle size, zeta potential, entrapment efficiency (EE%), 3-months storage stability, skin deposition/permeation, antioxidant potential, and morphology. Aspasomes antibacterial efficacy on Propionibacterium acnes using the zone of inhibition assay was also tested, whilst their safety on skin fibroblastic cells was assessed in vitro using 3T3 CCL92 …

Stable Flies, Stomoxys Calcitrans L. (Diptera: Muscidae), Improve Offspring Fitness By Avoiding Oviposition Substrates With Competitors Or Parasites, Steve B.S. Baleba, Baldwyn Torto, Daniel Masiga, Merid N. Getahun, Christopher W. Weldon

All Peer-Reviewed Publications

Oviposition site selection by gravid female insects is an important determinant in species distribution, abundance, and population dynamics. Females may assess the suitability of a potential oviposition substrate by using cues from conspecific or heterospecific individuals already present. Here, we assessed whether the presence of conspecific or heterospecific larvae and parasites influenced oviposition decisions by the stable fly, Stomoxys calcitrans (Linneaus). Using dual and multiple-choice oviposition bioassays, we found that gravid female S. calcitrans avoided substrates with conspecific larvae, the larvae of house flies, Musca domestica (Linneaus), and the mite Macrocheles muscaedomesticae (Scopoli). Avoidance of conspecific and heterospecific larvae persisted …

Reference Value For The Six-Minute Peg Board And Ring Test. A Cross Sectional Study, Manjiri Suhas Kulkarni, Gopala Krishna Alaparthi, Shyam Krishnan, Anand Ramakrishna

Open Access archive

Introduction: In our daily life, arm activities, whether supported or unsupported play a major role. Both simple and complex activities require the muscles, namely trapezius, pectoralis minor, scalene, and intercostals, to participate in arm positioning. These muscles also enact as the accessory respiratory muscles. Therefore, arm elevation increases the load on these muscles and they fail to perform dual activities, resulting in arm fatigue and a feeling of dyspnoea in healthy individuals as well as in chronic obstructive pulmonary disease patients. Various upper limb exercise tests were designed to measure this impairment, one of them being the six-minute peg board …

Comparison Of Londrina Activities Of Daily Living Protocol And Glittre Adl Test On Cardio-Pulmonary Response In Patients With Copd: A Cross-Sectional Study, Chaitali Deshpande, Gopala Krishna Alaparthi, Shyam Krishnan, Kalyan Chakravarthy Bairapareddy

Open Access archive

Background: In COPD patients it is very important to assess the activities of daily living (ADL) due to an impairment of independence and quality of life. There is a lack of retrievable data regarding the cardio-pulmonary response to Londrina ADL protocol in patients with COPD. The aim of the present study was to assess the cardio-pulmonary response to Londrina ADL protocol in patients with COPD and to compare this with responses to the Glittre ADL test. Methods: This cross-sectional study was done on 30 COPD subjects. Each subject was taken to perform the Londrina ADL protocol, Glittre ADL test, twice …

Back To Music: Disabled Musicians And The Loss Of Music, Nuria Bonet

School of Art, Design and Architecture

For musicians, professionals and amateurs, performing music can have a central role in their life. While it can determine their social, professional and cultural life, it also determines their identity. Playing an instrument can connect you to people with similar knowledge and experiences, and, most importantly, passion. Losing the ability to play one’s instrument can therefore be devastating to an individual, as they lose a part of themselves.

Cross-Subunit Catalysis And A New Phenomenon Of Recessive Resurrection In Escherichia Coli Rnase E, Nida Ali, Jayaraman Gowrishankar

Open Access archive

RNase E is a 472-kDa homo-Tetrameric essential endoribonuclease involved in RNA processing and turnover in Escherichia coli. In its N-Terminal half (NTH) is the catalytic active site, as also a substrate 5′-sensor pocket that renders enzyme activity maximal on 5′-monophosphorylated RNAs. The protein's non-catalytic C-Terminal half (CTH) harbours RNA-binding motifs and serves as scaffold for a multiprotein degradosome complex, but is dispensable for viability. Here, we provide evidence that a full-length hetero-Tetramer, composed of a mixture of wild-Type and (recessive lethal) active-site mutant subunits, exhibits identical activity in vivo as the wild-Type homo-Tetramer itself ('recessive resurrection'). When all of the …

Changing The Paradigm In Armenia-Diaspora Relations: State-Centered Institutions And Transnational Governance, Nerses Kopalyan

Political Science Faculty Research

Nation-states that encompass large Diasporas are faced with the wider responsibility of accounting for two types of members: citizens that live within the territory of the state and members of the broader nation that reside in the Diaspora. In the Armenian case, legally speaking, an Armenian is a citizen of the Republic of Armenia; but, at the same time, a diasporan Armenian is equally qualified as an Armenian, even if they do not live within the legal boundaries of the state.

Documents From The January 22, 2020 Meeting Of The Associated Students Of The University Of Montana (Asum), University Of Montana--Missoula. Associated Students

Senate Meeting Agendas and Minutes, 2007-Present

Agenda and meeting minutes from the January 22, 2020 meeting of the Associated Students of the University of Montana (ASUM). The following resolutions were discussed during the meeting:

SB46-19/20: Resolution Adjusting Student Employee Hours to Reflect a Biweekly Pay Period

SB49-19/20: Resolution Amending Section 20 of Fiscal Policy

SB50-19/20: Resolution Regarding the Renovation and Expansion of the Music Building

Isoniazid-Resistant Tuberculosis: A Problem We Can No Longer Ignore, Giorgia Sulis, Madhukar Pai

Open Access archive

No abstract provided.