Digital Commons Network^™

Overview Of Extensively Employed Polymeric Carriers In Solid Dispersion Technology, Athira R. Nair, Yarlagadda Dani Lakshman, Vullendula Sai Krishna Anand, K. S.Navya Sree

Open Access archive

Solid dispersion is the preferred technology to prepare efficacious forms of BCS class-II/IV APIs. To prepare solid dispersions, there exist a wide variety of polymeric carriers with interesting physicochemical and thermochemical characteristics available at the disposal of a formulation scientist. Since the advent of the solid dispersion technology in the early 1960s, there have been more than 5000 scientific papers published in the subject area. This review discusses the polymeric carrier properties of most extensively used polymers PVP, Copovidone, PEG, HPMC, HPMCAS, and Soluplus® in the solid dispersion technology. The literature trends about preparation techniques, dissolution, and stability improvement are …

Letter To The Editor Regarding ‘Stepping Up: How U.S. Neurosurgery Training Programs Can Innovatively Assess Resident Applicants In A Post-Step 1 World’, Bukkambudhi V. Murlimanju, Md Moshiur Rahman, Luis Rafael Moscote-Salazar, Manoor D. Prameela

Open Access archive

No abstract provided.

Covid-19 Disparity Among Racial And Ethnic Minorities In The Us: A Cross Sectional Analysis, Raghavendra Tirupathi, Valeriia Muradova, Raj Shekhar, Sohail Abdul Salim

Open Access archive

Aim: To analyze racial disparities in Coronavirus disease (COVID-19) cases in the United States of America and discuss possible reasons behind this inequality. Subject and methods: We obtained estimated case counts of African-American, Caucasian, Native American, Asian and Hispanic individuals with coronavirus disease (COVID-19)infection through May 5, 2020, from publicly available data on state departments of health websites. We calculated race-specific fractions as the percentage of the total population and analyzed the reasons behind this disparity. Results: The incident rates of COVID-19 were higher among African Americans and among Latinos disproportionately higher than their representation in 14 states and 9 …

Fetal Echocardiography At Term In Diabetic Pregnancies Helps Predict The Adverse Neonatal Outcome - Results Of A Prospective Observational Study From South India, Grandhi Mrudhula Tejaswi, Jyothi Samanth, Akhila Vasudeva, Leslie Lewis

Open Access archive

There is sparse Indian data on whether fetal echocardiography among pregnant diabetics would be useful to predict adverse perinatal/neonatal outcome. Objectives: To study fetal cardiac changes in diabetic mothers and non-diabetic controls from 24 weeks gestation until the neonatal period; correlate them with maternal glycemic control; study their implications on adverse perinatal/neonatal outcome. Methodology: Prospective observational cohort study. Pregnant diabetics (17 overt, 66 gestational) recruited beyond 24 weeks, divided as well (39) and poorly (44) controlled, based on American Diabetes Association 2016 criteria. Controls were 102 healthy non-diabetic pregnancies. Fetal echocardiography performed at weeks 24–32, 32–36, >37, and between 4 …

Anti-Snake Venom And Methanolic Extract Of Andrographis Paniculata: A Multipronged Strategy To Neutralize Naja Naja Venom Acetylcholinesterase And Hyaluronidase, Akshatha Ganesh Nayak, Nitesh Kumar, Smita Shenoy, Maya Roche

Open Access archive

The study investigates the ability of methanolic extract of Andrographis paniculata (MAP) to supplement polyvalent anti-snake venom (ASV) in inhibiting neurotoxic enzyme acetylcholinesterase (AChE) and ‘spreading factor’ hyaluronidase from Naja naja (N.N) venom. AChE and hyaluronidase activity were measured in 100 or 200 µg of crude venom, respectively, and designated as ‘control’. In Test Group I, enzyme assays were performed immediately after the addition of ASV/MAP/ASV + MAP to the venom. Inhibition of AChE by ASV (100–367 µg) was 12–17%, and of hyaluronidase (22–660 µg) was 33–41%. Under the same conditions, MAP (100–400 µg) inhibited AChE and hyaluronidase to the …

Dr. Chandrasekaran's Reply To “Exercising And Face Masks: An Important Hypothesis Buried In A Selective Review”, Baskaran Chandrasekaran, Shifra Fernandes

Open Access archive

No abstract provided.

Signaling Pathways Promoting Epithelial Mesenchymal Transition In Oral Submucous Fibrosis And Oral Squamous Cell Carcinoma, Smitha Sammith Shetty, Mohit Sharma, Felipe Paiva Fonseca, Pradyumna Jayaram

Open Access archive

Epithelial-mesenchymal transition (EMT) is a critical process that occurs during the embryonic development, wound healing, organ fibrosis and the onset of malignancy. Emerging evidence suggests that the EMT is involved in the invasion and metastasis of cancers. The inflammatory reaction antecedent to fibrosis in the onset of oral submucous fibrosis (OSF) and the role of EMT in its malignant transformation indicates a hitherto unexplored involvement of EMT. This review focuses on the role of EMT markers which are regulators of the EMT mediated complex network of molecular mechanisms involved in the pathogenesis of OSF and OSCC. Further the gene enrichment …

“Exercise With Facemask; Are We Handling A Devil's Sword?” – A Physiological Hypothesis, Baskaran Chandrasekaran, Shifra Fernandes

Open Access archive

Straying away from a sedentary lifestyle is essential, especially in these troubled times of a global pandemic to reverse the ill effects associated with the health risks as mentioned earlier. In the view of anticipated effects on immune system and prevention against influenza and Covid-19, globally moderate to vigorous exercises are advocated wearing protective equipment such as facemasks. Though WHO supports facemasks only for Covid-19 patients, healthy “social exercisers” too exercise strenuously with customized facemasks or N95 which hypothesized to pose more significant health risks and tax various physiological systems especially pulmonary, circulatory and immune systems. Exercising with facemasks may …

Knowledge And Understanding Among Medical Imaging Professionals In India During The Rapid Rise Of The Covid-19 Pandemic, Rahul P. Kotian, Disha Faujdar, Sneha P. Kotian, Brayal D’Souza

Open Access archive

During the first week of March,2020 the surge of coronavirus disease (COVID-19) cases reached all over the globe with more than 100,000 cases. Healthcare national and international authorities have already initiated awareness and lockdown activities. A poor understanding of the disease among medical imaging professionals (MIPs) may result in rapid spread of infection. This study aimed to investigate the knowledge and understanding of MIPs about COVID-19. A cross-sectional, web-based study was conducted among MIPs about COVID- 19 during the fourth week of March 2020. An online sample of MIPs was successfully recruited via the authors’ networks in India using data …

Indian Guidelines On Hypertension-Iv (2019), Siddharth N. Shah, Y. P. Munjal, Sandhya A. Kamath, Gurpreet S. Wander

Open Access archive

No abstract provided.

Microrna's – The Vibrant Performers In The Oral Cancer Scenario, Monica Charlotte Solomon, Raghu Anekal Radhakrishnan

Open Access archive

MicroRNAs (miRNAs) are a family of small non-coding (18–22 nucleotide) RNA molecules. These molecules regulate gene expression by either inhibiting mRNA translation or by degrading mRNA. A single miRNA can control the expression of target genes, and the expression of a target gene can be regulated by multiple miRNAs. They are key regulators of various biological and pathological processes. These include cell proliferation, development and tumorigenesis. Novel studies have discovered definite signature miRNAs in the initiation and progression of cancers. Interestingly, miRNAs have also been found in fragile genomic sites that are associated with increased cancer risk. These micro RNAs …

Intention And Barriers To Use Moocs: An Investigation Among The Post Graduate Students In India, M. Mithun Mohan, Pallavi Upadhyaya, K. Rajasekharan Pillai

Open Access archive

Massive Open Online Courses (MOOCs) have widely been acknowledged as a unified platform to reduce the digital divide and make education accessible to all. It also enables students’ access to professors and educational contents sans spatial and institutional barriers. Despite several benefits, MOOCs’ adoption and completion rate remain unimpressive, especially among developing countries. Using Extended Unified Theory of Acceptance and Use of Technology (UTAUT2), we examine the key factors that influence the behavioral intention to use MOOCs among students in an Indian private university. The data from 412 postgraduate students were analyzed using Partial Least Squares-Structured Equation Modelling. The study …

Does The Timing Of Treatment Affect Complications Of Pediatric Femoral Neck Fractures?, Kumar Amerendra Singh, Vidyasagar Chandankere, Hitesh Shah

Open Access archive

Objectives: Pediatric femoral neck fractures were reviewed to compare complications with the time of presentation. Methods: 34 pediatric femoral neck fractures were studied to detect union time, avascular necrosis, premature physis fusion, and the neck-shaft angle. All complications were comparable between both groups. Results: The mean union time was more in late presented group. Four children developed AVN. The neck shaft angle and pre mature fusion of growth plate were same in both groups. Conclusions: The frequency of the complications except union time in pediatric neck femur fracture is comparable in early and late presented groups.

Effectiveness Of Novel Herbal Dentifrice In Control Of Plaque, Gingivitis, And Halitosis – Randomized Controlled Trial, Kalyana Chakravarthy Pentapati, Meena Anand Kukkamalla, Hanan Siddiq, Neeraja Sabnis

Open Access archive

Background and aim: Plaque is a common etiological factor for common oral conditions like gingivitis, periodontitis, dental caries and halitosis. We aimed to evaluate the efficacy of a novel herbal dentifrice in control of plaque, gingivitis, and halitosis in comparison to control dentifrice. Experimental procedure: We conducted a randomized controlled, single center, double-blinded parallel arm clinical trial. Participants were randomly distributed with commercially available herbal dentifrice or control dentifrice. Assessments of plaque, gingivitis, halitosis, unstimulated saliva pH were done at baseline and at one month by a trained and calibrated periodontist. All the participants were given new toothbrushes one week …

2. Plot_Va.Pro, Katariina Nykyri

MMS Observations of the Multi-Scale Wave Structures and Parallel Electron Heating in the Vicinity of the Southern Exterior Cusp

The file contains the IDL code for plotting the result.

5. Plot_Va_Trace.Pro, Katariina Nykyri

MMS Observations of the Multi-Scale Wave Structures and Parallel Electron Heating in the Vicinity of the Southern Exterior Cusp

The file contains the IDL code for plotting the result of the virtual spacecraft measurement.

First Report Of A Gall Midge As A Parasitoid Of Weaver Ants, Bethelihem Mekonnen, Julien Haran, Robert S. Copeland, Christian W.W. Pirk, Abdullahi A. Yusuf, Emilie Deletre

All Peer-Reviewed Publications

Gall midges (Diptera: Cecidomyiidae) comprise a diverse family of small nematoceran flies. While most species are phytophagous, the family also includes predatory species, and endoparasitoids. Endoparasitic species have been reared from aphids and psyllids. We discovered parasitoid-infected weaver ant, Oecophylla longinoda (Latreille) (Hymenoptera: Formicidae) in nests on mango trees in coastal Kenya. Examination of 5 colonies revealed the presence of parasitoids in all of them, with parasitism rates ranging from 2 to 21%. Morphological examination of larval parasitoids indicated that they were gall midges, and molecular data were consistent with the identification. Attempts to rear adults were unsuccessful. This study …

Data For "An Experimental Investigation Of Health Insurance Policy And Behavior", J. Dustin Tracy, Hillard Kaplan, Kevin James, Stephen Rassenti

ESI Data Sets

We introduce a new experimental approach to measuring the effects of health insurance policy alternatives on behavior and health outcomes over the life course. Cash-motivated subjects are placed in a virtual environment where they earn income and allocate it across multi-period lives. We compare behavior across age, income and insurance plans---one priced according to an individual's expected cost and the other uniformly priced through employer-implemented cost sharing. We find that 1) subjects in the employer-implemented plan purchased insurance at higher rates; 2) the employer-based plan reduced differences due to income and age; 3) subjects in the actuarial plan engaged in …

2020-10-31_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

2020-10-31_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2020-10-30_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2020-10-30_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

The Classic Pellagra Dermatitis, Sharath P. Madhyastha, Ganesh V. Shetty, Varsha M. Shetty, Charan T. Reddy

Open Access archive

No abstract provided.

How To Cope With Election-Related Stress, University Marketing And Communications, Jocelyn Carter

DePaul Download

If you’re feeling uneasy or frustrated this election-season, you are not alone. The American Psychological Association found that many people are citing the 2020 elections as a significant source of stress in their life. To learn more about election-related stress and how to cope with it, listen to latest episode with Jocelyn Carter, associate professor in DePaul’s College of Science and Health and director of clinical training.

2020-10-29_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Perceived Work Uncertainty And Creativity During The Covid-19 Pandemic: The Roles Of Zhongyong And Creative Self-Efficacy, Chaoying Tang, Huijuan Ma, Stefanie E. Naumann, Ziwei Xing

Eberhardt School of Business Faculty Articles

Research on the relationship between work stress and employee creativity has been mixed. This study on 823 female attorneys in China identifies employee creative self-efficacy and employees’ value of Zhongyong as moderators in this relationship. In this study, work stress is assessed by the perceived work uncertainty brought on by the COVID-19 pandemic. Our study found that although Zhongyong, which involves an employee’s ambidextrous thinking, can be helpful for employee creativity, low levels of Zhongyong are better for employee creativity in an uncertain context such as the COVID-19 pandemic, due to the fact that high levels of Zhongyong result in …

Atlantic Salmon (Salmo Salar) Neurocranium, Connor Depriest, Nadia Abeido, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

9.0 cm in length. Neurocranium scan of an Atlantic Salmon (Salmo salar). Collected from Two Bills Seafood on 04/09/20 by Nadia Abeido and Connor Depriest.

Edax And Ftir Characterization And Setting Time Of An Experimental Nanoparticle Incorporated Root-End Filling Material, Teena Sheethal Dsouza, Aditya Shetty, Mithra Nidarsh Hegde, Jenitta Emima Packayam

Open Access archive

The evolution of calcium silicate based cements in the field of dentistry has been rewarding. It offers a plethora of advantages with respect to physicochemical and biological properties. However, the extended setting time and limited antibacterial activity in these cements is quite a concern. This study aimed to develop a fast-setting nanoparticle incorporated root-end filling material for use after periapical surgeries. With the incorporation of the silver nanoparticles, and using calcium chloride as the liquid component, the desirable study outcome was achieved. The setting time was significantly reduced when compared to the commercially available root-end filling material.

Matrices Of Connectivity, Community Structure, And Geographic Distance, Between Six Provinces In The Gulf Of Mexico, Claire B. Paris, Igal Berenshtein

C-IMAGE data

The dataset contains matrices describing the relationship between six provinces in the Gulf of Mexico (GoM) in terms of the Lagrangian dynamical geography of the GoM regions, the community structure of demersal fish, the potential for larval connectivity, and geographic distance. The six provinces are West Florida Shelf (WSF), North Central (NC) North West (NW), South West (SW), Yucatan Peninsula (YP), and Cuba (CUB). The similarity in community structure was computed for marine demersal fish based on the gulf-wide bottom longline survey is archived in GRIIDC Unique Dataset Identifier (UDI) R4.x267.000:0039 (DOI: 10.7266/N7G73C4N). Connectivity matrices were computed for larval tuna, …

2020-10-28_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …