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Derma Rollers In Therapy: The Transition From Cosmetics To Transdermal Drug Delivery, Leonna Dsouza, Vivek M. Ghate, Shaila A. Lewis Dec 2020

Derma Rollers In Therapy: The Transition From Cosmetics To Transdermal Drug Delivery, Leonna Dsouza, Vivek M. Ghate, Shaila A. Lewis

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Derma roller, a device rolled onto the skin to form micropores, is extensively used for cosmetic purposes. The pores thus created are utilized to either result in the induction of collagen production, leading to glowing and wrinkle-free skin or for permeating the applied formulations to the site of action within the skin. Recent studies have shown the benefits of using derma rollers for transdermal delivery of drugs. In the nascent stage, this approach paves a way to successfully breach the stratum corneum and aid in the movement of medications directed towards the dermis and the hair follicles. The review essentially …

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A Triple Band Modified F-Shaped Monopole Antenna For Rfid Application, Spoorti Barigidad, Aishwarya C. Yeshawant, Sridevi Rao, C. A. Tharunya Dec 2020

A Triple Band Modified F-Shaped Monopole Antenna For Rfid Application, Spoorti Barigidad, Aishwarya C. Yeshawant, Sridevi Rao, C. A. Tharunya

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Radio frequency identification (RFID) is a very prominent technology and is used in object-attached identification and tracking tags. In this paper a triple band monopole antenna is designed to work at 2.2-2.6 GHz (lower RFID band), 5.3-6.8 GHz and 8.7-9.5 GHz (upper RFID band) frequency ranges. The antenna design resembles a modified F-shaped radiator and is built on a low cost easily available FR4 dielectric substrate. Initially an F-shaped radiator with partial ground plane is studied which exhibits the operation at 2.6 and 6.5 GHz. Further, modifying this F-shaped radiator exhibits an additional resonance at 9.2 GHz. Fundamental characteristics such …

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Involvement Of The Nervous System In Covid-19: The Bell Should Toll In The Brain, Sairaj Satarker, Madhavan Nampoothiri Dec 2020

Involvement Of The Nervous System In Covid-19: The Bell Should Toll In The Brain, Sairaj Satarker, Madhavan Nampoothiri

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The world is fuming at SARS-CoV-2 for being the culprit for causing the devastating COVID-19, claiming millions of lives across the globe in the form of respiratory disorders. But lesser known are its effects on the CNS that are slowly surfacing in the worldwide population. Our review illustrates findings that claim SARS-CoV-2's arrival onto the ACE2 receptors of neuronal and glial cells mainly via CSF, olfactory nerve, trigeminal nerve, neuronal dissemination, and hematogenous pathways. The role of SARS-CoV-2 structural proteins in its smooth viral infectivity of the host cannot be ignored, especially the spike proteins that mediate spike attachment and …

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A Decentralized Consensus Application Using Blockchain Ecosystem, Chetana Pujari, Balachandra Muniyal, C. B. Chandrakala Dec 2020

A Decentralized Consensus Application Using Blockchain Ecosystem, Chetana Pujari, Balachandra Muniyal, C. B. Chandrakala

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The consensus is a critical operation of any decision-making process. It involves a set of eligible members; whose decision need to be honored by taking their acknowledgment before making any decision. The traditional consensus process follows centralized architecture, the members need to rely on and trust this architecture. The proposed system aims to develop a secure decentralized consensus application in the untrusted environment by making use of blockchain technology along with smart contract and interplanetary file system (IPFS).

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Fertility Preservation During The Covid-19 Pandemic: Mitigating The Viral Contamination Risk To Reproductive Cells In Cryostorage, Satish K. Adiga, Prathima Tholeti, Shubhashree Uppangala, Guruprasad Kalthur Dec 2020

Fertility Preservation During The Covid-19 Pandemic: Mitigating The Viral Contamination Risk To Reproductive Cells In Cryostorage, Satish K. Adiga, Prathima Tholeti, Shubhashree Uppangala, Guruprasad Kalthur

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Reopening fertility care services across the world in the midst of a pandemic brings with it numerous concerns that need immediate addressing, such as the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the male and female reproductive cells and the plausible risk of cross-contamination and transmission. Due to the novelty of the disease the literature contains few reports confirming an association of SARS-CoV-2 with reproductive tissues, gametes and embryos. Cryobanking, an essential service in fertility preservation, carries the risk of cross-contamination through cryogenic medium and thus calls for risk-mitigation strategies. This review aims to address the available …

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Synthesis, Anticancer And Molecular Docking Studies Of New Class Of Benzoisoxazolyl-Piperidinyl-1, 2, 3-Triazoles, Govindhan Muniyappan, Subramanian Kathavarayan, Chandrasekar Balachandran, Easwaramoorthi Kalliyappan Dec 2020

Synthesis, Anticancer And Molecular Docking Studies Of New Class Of Benzoisoxazolyl-Piperidinyl-1, 2, 3-Triazoles, Govindhan Muniyappan, Subramanian Kathavarayan, Chandrasekar Balachandran, Easwaramoorthi Kalliyappan

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A small library of hitherto unexplored novel 5-fluorobenzoisoxazolyl-piperidinyl-1, 2, 3-triazole derivatives has been synthesized from 2-azido-fluorobenzoisoxazolyl piperidinyl ethanone and various alkynes in good to excellent yields through a click chemistry approach. Compounds thus synthesized were evaluated for their cytotoxicity against HepG-2 and A549 cancer cells. Interestingly, compounds 4c, 4d, 4e and 4h displayed significant cytotoxicity against HepG-2 and A549 cancer cells. Toxicity study of active compounds was compared with human normal lung IMR-90 cells. Molecular docking has also been investigated for 4a-i with Chk1 protein and the compounds 4c and 4h displayed reasonable molecular interactions with good docking scores.

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Comparison Of Strategies In Development And Manufacturing Of Low Viscosity, Ultra-High Concentration Formulation For Igg1 Antibody, Vaibhav Deokar, Alok Sharma, Rustom Mody, Subrahmanyam M. Volety Dec 2020

Comparison Of Strategies In Development And Manufacturing Of Low Viscosity, Ultra-High Concentration Formulation For Igg1 Antibody, Vaibhav Deokar, Alok Sharma, Rustom Mody, Subrahmanyam M. Volety

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Monoclonal antibodies requiring higher doses for exerting therapeutic effect but having lower stability, are administered as dilute infusions, or as two (low concentration) injections both resulting in reduced patient compliance. Present research summarizes impact of manufacturing conditions on ultra-high concentration (≥150 mg/mL) IgG1 formulation, which can be administered as one subcutaneous injection. IgG1 was concentrated to ~200 mg/mL using tangential flow filtration (TFF). Alternatively, spray dried (SPD) and spray freeze dried (SFD) IgG1, was reconstituted in 30%v/v propylene glycol to form ultra-high concentration (~200 mg/mL) injectable formulation. Reconstituted, SPD and SFD IgG1 formulations, increased viscosity beyond an acceptable range for …

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Use Of Videos And Digital Media In Parent-Implemented Interventions For Parents Of Children With Primary Speech Sound And/Or Language Disorders: A Scoping Review, Monica L. Bellon-Harn, Lekeitha R. Morris, Vinaya Manchaiah, William E. Harn Dec 2020

Use Of Videos And Digital Media In Parent-Implemented Interventions For Parents Of Children With Primary Speech Sound And/Or Language Disorders: A Scoping Review, Monica L. Bellon-Harn, Lekeitha R. Morris, Vinaya Manchaiah, William E. Harn

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No review to date has focused on evaluating the use of videos and digital media in parent-implemented interventions for parents of children with primary language or speech sound disorder (LD/SSD). Research objectives guiding this scoping review included an evaluation of (a) use of videos and/or other digital media in parent-implemented interventions; (b) use of videos and/or other digital media in asynchronous content; (c) the role of the parent as learner; and (d) the program impact on parents and children. This review followed a five-stage framework: (a) identify research questions; (b) identify relevant studies; (c) select studies; (d) chart the data; …

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“We Never Graduate From Care Giving Roles”; Cultural Schemas For Intergenerational Care Role Among Older Adults In Tanzania, Sylivia Karen Rutagumirwa, Inge Hutter, Ajay Bailey Dec 2020

“We Never Graduate From Care Giving Roles”; Cultural Schemas For Intergenerational Care Role Among Older Adults In Tanzania, Sylivia Karen Rutagumirwa, Inge Hutter, Ajay Bailey

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This paper examines the cultural schemas underlying older persons’ perception of intergenerational care roles. Thirty qualitative in-depth interviews and twenty focus group discussions (N = 120) were conducted among older women and men aged 60 and above. By using this theory, we were able to identify a series of cultural schemas found in older people’s discussions of intergenerational caregiving role. The most prominent shared schemas are; caregiving for elderly is a cultural obligation not a choice, caregiving is a sign of respect, caregiving is a sign of love, caregiving is a source of pride, and caregiving leads to attachment and …

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Rajyoga Meditation Induces Grey Matter Volume Changes In Regions That Process Reward And Happiness, M. G.Ramesh Babu, Rajagopal Kadavigere, Prakashini Koteshwara, Brijesh Sathian Dec 2020

Rajyoga Meditation Induces Grey Matter Volume Changes In Regions That Process Reward And Happiness, M. G.Ramesh Babu, Rajagopal Kadavigere, Prakashini Koteshwara, Brijesh Sathian

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Studies provide evidence that practicing meditation enhances neural plasticity in reward processing areas of brain. No studies till date, provide evidence of such changes in Rajyoga meditation (RM) practitioners. The present study aimed to identify grey matter volume (GMV) changes in reward processing areas of brain and its association with happiness scores in RM practitioners compared to non-meditators. Structural MRI of selected participants matched for age, gender and handedness (n = 40/group) were analyzed using voxel-based morphometric method and Oxford Happiness Questionnaire (OHQ) scores were correlated. Significant increase in OHQ happiness scores were observed in RM practitioners compared to non-meditators. …

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Role Of Fluorescence In Situ Hybridization In Detecting Mycobacterium Avium Complex Presenting As Fever In Treatment Failure Hiv, Vikas Prabhu, Steffi Coelho, Basavaprabhu Achappa, Shrikala Baliga Dec 2020

Role Of Fluorescence In Situ Hybridization In Detecting Mycobacterium Avium Complex Presenting As Fever In Treatment Failure Hiv, Vikas Prabhu, Steffi Coelho, Basavaprabhu Achappa, Shrikala Baliga

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A 49-year-old male HIV positive patient on treatment failure presented with complaints of fever and dysphagia of three weeks duration and later on developed cervical lymphadenopathy along with severe vomiting and abdominal pain. Liver function tests were found to be worsening with severe drop in CD4 counts. An extensive workup for pyrexia was done. FNAC and biopsy of lymph node showed features suggestive of granulomatous lymphadenitis. CBNAAT of the lymph node aspirate was negative for MTB. Blood culture and lymph node cultures were negative for Mycobacterium Avium Complex (MAC). MAC was however, finally detected and reported positive on Fluorescence in …

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Dynamics Of Human B And T Cell Adaptive Immune Responses To Kyasanur Forest Disease Virus Infection, Santhosha Devadiga, Anita K. Mcelroy, Suresha G. Prabhu, Govindakarnavar Arunkumar Dec 2020

Dynamics Of Human B And T Cell Adaptive Immune Responses To Kyasanur Forest Disease Virus Infection, Santhosha Devadiga, Anita K. Mcelroy, Suresha G. Prabhu, Govindakarnavar Arunkumar

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Kyasanur Forest disease (KFD) is a tick-borne, acute, febrile viral illness endemic in southern India. No major studies have been done to understand the adaptive immune response during KFDV infection in humans. In this study, KFDV-positive patients were prospectively enrolled, and repeated peripheral blood collections were performed. Clinical and virologic characterization of these samples is reported along with phenotypic analysis of cellular immunity and quantitation of humoral immunity. We noted robust T and B cell responses, particularly of CD8 T cells, during KFDV infection in most of the patients. Virus clearance from the blood coincided with peak CD8 T cell …

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Reply To: Cadaverless Anatomy: Darkness In The Times Of Pandemic Covid-19, B. V. Murlimanju, A. Agrawal, M. M. Pai, L. V. Prabhu Dec 2020

Reply To: Cadaverless Anatomy: Darkness In The Times Of Pandemic Covid-19, B. V. Murlimanju, A. Agrawal, M. M. Pai, L. V. Prabhu

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No abstract provided.

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Temporal Self-Similarity Of Quantum Dynamical Maps As A Concept Of Memorylessness, Shrikant Utagi, R. Srikanth, Subhashish Banerjee Dec 2020

Temporal Self-Similarity Of Quantum Dynamical Maps As A Concept Of Memorylessness, Shrikant Utagi, R. Srikanth, Subhashish Banerjee

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The problem of defining quantum non-Markovianity has proven elusive, with various in-equivalent criteria put forth to address it. The concept of CP-indivisibility and the hierarchy of stronger divisibility criteria going up to P-indivisibility, capture a fundamental aspect of memory in quantum non-Markovianity. In practice, however, there can be a memory-like influence associated with divisible channels in the form of weakening, if not reversing, the effects of decoherence. Arguably, such a facet of memory relates to CP-indivisibility as quantum discord relates to entanglement. We concretize this weaker notion of non-Markovianity by identifying it with deviation from “temporal self-similarity”, the property of …

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The Relationship Between Physical Fitness Attributes And Sports Injury In Female, Team Ball Sport Players: A Systematic Review, Jessica B. Farley, Lily M. Barrett, Justin W.L. Keogh, Carl T. Woods Dec 2020

The Relationship Between Physical Fitness Attributes And Sports Injury In Female, Team Ball Sport Players: A Systematic Review, Jessica B. Farley, Lily M. Barrett, Justin W.L. Keogh, Carl T. Woods

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Background: Understanding the relationships between physical fitness characteristics and sports injury may assist with the development of injury minimisation programs. The purpose of this systematic review was to investigate the association between physical fitness attributes and sports injury in female, team ball sport players. Methods: Four scientific databases (MEDLINE, EMBASE, SPORTDiscus, Scopus) and reference lists of relevant research were searched for eligible studies up to September 2, 2019. Full-text articles examining the relationship between physical fitness and sports injury in female, team ball sport players were included. A modified Downs and Black checklist was used to assess methodological quality. Data …

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Modulation Index Effect On Inverter Based Induction Motor Drive, Akhilesh Sharma, N. Anandh, Sarsing Gao Dec 2020

Modulation Index Effect On Inverter Based Induction Motor Drive, Akhilesh Sharma, N. Anandh, Sarsing Gao

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Due to a substantial increase in the use of inverter for numerous electrical appliances starting from domestics to industrial drives, an inverter may be directly connected to the power grid system. The dependency on an inverter has been increased over the years. Hence, the proper and efficient design of the inverter will lead to higher efficiency. One of the major challenges is the generation of suitable gate pulses for power switching devices, which in turn depends on the modulation index. The selection of proper modulation index will help in the production of the rated voltage. If the modulation index is …

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Glucose Induces Metabolic Reprogramming In Neutrophils During Type 2 Diabetes To Form Constitutive Extracellular Traps And Decreased Responsiveness To Lipopolysaccharides, Manjunath B. Joshi, Rayees Ahamed, Mangala Hegde, Aswathy S. Nair Dec 2020

Glucose Induces Metabolic Reprogramming In Neutrophils During Type 2 Diabetes To Form Constitutive Extracellular Traps And Decreased Responsiveness To Lipopolysaccharides, Manjunath B. Joshi, Rayees Ahamed, Mangala Hegde, Aswathy S. Nair

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Recurrent infections are one of the common morbidities in Type 2 Diabetes (T2D) subjects. Bidirectional activation of innate immune cells such as neutrophils and glucose metabolism in T2D conditions leads to a pro-inflammatory milieu and reduced neutrophil function, which can be a potential cause for recurrent infections. In pathological conditions of sterile inflammation associated T2D, neutrophils form constitutive extracellular traps (NETs) due to hyperglycemia and respond poorly to infections. The present study was aimed at understanding the cellular and metabolic consequences, and NETs formation in T2D. We show that glucose induces NADPH oxidase derived reactive oxygen species and further citrullinates …

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Risk Of Eye Infections In Dental Personnel And The Need For Its Prevention: A Case Report, Ritvi Arvind, M. Roma Dec 2020

Risk Of Eye Infections In Dental Personnel And The Need For Its Prevention: A Case Report, Ritvi Arvind, M. Roma

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A lot of dentists and dental personnel are at high risk of contracting eye infections during operative procedures involving aerosols. As many may not be aware of it, they often ignore the precautions to be taken for prevention of such infections. This is one such case report of a dental intern where an eyelid infection arose shortly after she treated a patient with an infected tooth in an operative procedure. This case report emphasizes the importance of preventive barriers for the dentist, and that how special protective gear is required for doing restorative cases which involve dealing with infection.

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Loss Of Oral Mucosal Stem Cell Markers In Oral Submucous Fibrosis And Their Reactivation In Malignant Transformation, Mohit Sharma, Felipe Paiva Fonseca, Keith D. Hunter, Raghu Radhakrishnan Dec 2020

Loss Of Oral Mucosal Stem Cell Markers In Oral Submucous Fibrosis And Their Reactivation In Malignant Transformation, Mohit Sharma, Felipe Paiva Fonseca, Keith D. Hunter, Raghu Radhakrishnan

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The integrity of the basal stem cell layer is critical for epithelial homoeostasis. In this paper, we review the expression of oral mucosal stem cell markers (OM-SCMs) in oral submucous fibrosis (OSF), oral potentially malignant disorders (OPMDs) and oral squamous cell carcinoma (OSCC) to understand the role of basal cells in potentiating cancer stem cell behaviour in OSF. While the loss of basal cell clonogenicity triggers epithelial atrophy in OSF, the transition of the epithelium from atrophic to hyperplastic and eventually neoplastic involves the reactivation of basal stemness. The vacillating expression patterns of OM-SCMs confirm the role of keratins 5, …

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Berberine, A Natural Alkaloid Sensitizes Human Hepatocarcinoma To Ionizing Radiation By Blocking Autophagy And Cell Cycle Arrest Resulting In Senescence, Gautham Ramesh, Shubhankar Das, Satish Rao Bola Sadashiva Dec 2020

Berberine, A Natural Alkaloid Sensitizes Human Hepatocarcinoma To Ionizing Radiation By Blocking Autophagy And Cell Cycle Arrest Resulting In Senescence, Gautham Ramesh, Shubhankar Das, Satish Rao Bola Sadashiva

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Objective: To study the radiosensitizing potential of Berberine and the underlying mechanism in human hepatocarcinoma (HepG2) cells. Methods: HepG2 cells were challenged with X-rays in combination with Berberine treatment and several in vitro assays were performed. Alteration in cell viability was determined by MTT assay. Changes in intracellular ROS levels, mitochondrial membrane potential/mass, intracellular acidic vesicular organelles as well as cell cycle arrest and apoptotic cell death were analysed by flow cytometry. Induction of autophagy was assessed by staining the cells with Monodansylcadaverine/Lysotracker red dyes and immunoblotting for LC3I/II and p62 proteins. Phase-contrast/fluorescence microscopy was employed to study mitotic catastrophe …

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Electrochemical Approaches For Material Conservation: Experimental And Theoretical Insights Using A Biopolymer, Mikitha Pais, Padmalatha Rao Dec 2020

Electrochemical Approaches For Material Conservation: Experimental And Theoretical Insights Using A Biopolymer, Mikitha Pais, Padmalatha Rao

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Maltodextrin (MLD) is introduced as a novel, potent green inhibitor for the corrosion control of zinc in 0.1 sulfamic acid. The corrosion and inhibition studies were done by electrochemical techniques such as potentiodynamic polarisation measurements and electrochemical impedance spectroscopy technique. Conditions were optimised to get maximum inhibition efficiency by varying the concentration of the inhibitor in the temperature range of 303–323 K. Activation and thermodynamic parameters were evaluated and discussed in detail. Suitable mechanism was proposed for corrosion and inhibition process. Surface characterisation was done by SEM, EDX and AFM techniques before and after the addition of inhibitor. The density …

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Association Between Serum Micronutrient Levels And Febrile Seizures Among Febrile Children In Southern India: A Case Control Study, Lakmeel Kannachamkandy, Sowmini P. Kamath, Prasanna Mithra, K. Jayashree Dec 2020

Association Between Serum Micronutrient Levels And Febrile Seizures Among Febrile Children In Southern India: A Case Control Study, Lakmeel Kannachamkandy, Sowmini P. Kamath, Prasanna Mithra, K. Jayashree

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Background: Febrile seizures are prevalent in children. Interactions between the neurotransmitters and micronutrients levels in the biological fluids have been implicated in its occurrence. Objective: To assess the serum copper (Cu), magnesium (Mg) and zinc (Zn) levels in febrile children and to evaluate their association with febrile seizures. Methods: The study included 35 children with febrile seizures as cases and 35 children with febrile illnesses without seizures as controls. Children between six months to five years were included in the study group. The serum Cu, Mg and Zn levels were analyzed by the semi-auto analyzer. Data analysis was done using …

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Surgical Management Of The Congenital Dislocation Of The Knee And Hip In Children Presented After Six Months Of Age, Amrath Raj Amrath, Kumar Amerendra Singh, Hitesh Shah Dec 2020

Surgical Management Of The Congenital Dislocation Of The Knee And Hip In Children Presented After Six Months Of Age, Amrath Raj Amrath, Kumar Amerendra Singh, Hitesh Shah

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Purpose: Congenital dislocation of the knee and hip is a rare congenital disorder. The specific aim of the study was to evaluate the clinical and radiological outcomes of the children with congenital dislocation of the knee and hip who presented after six months of age. Methods: All the consecutive children with congenital dislocation of the knee and hip joints were retrospectively reviewed. We included cases that were treated after six months of age and followed up for a minimum of two years. Twenty-four children with congenital dislocation of the knee and hip (thirteen with ligamentous laxity, eleven children with stiff …

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Solid Acid Catalyzed Carboxymethylation Of Bio-Derived Alcohols: An Efficient Process For The Synthesis Of Alkyl Methyl Carbonates, Kempanna S. Kanakikodi, Sathyapal R. Churipard, A. B. Halgeri, Sanjeev P. Maradur Dec 2020

Solid Acid Catalyzed Carboxymethylation Of Bio-Derived Alcohols: An Efficient Process For The Synthesis Of Alkyl Methyl Carbonates, Kempanna S. Kanakikodi, Sathyapal R. Churipard, A. B. Halgeri, Sanjeev P. Maradur

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Acid catalyzed carboxymethylation of alcohols is an emerging organic transformation that has grabbed the attention of scientific community in recent years. In the present study, sulfonated mesoporous polymer (MP-SO3H) is presented as a highly active solid acid catalyst to convert a wide range of alcohols into alkyl methyl carbonates. The remarkable catalytic activity of MP-SO3H is comparable to that of reported homogeneous acid catalysts. A good correlation was established between the catalytic activity and textural properties of the material. An exceptional catalytic activity of MP-SO3H was observed for DMC mediated carboxymethylation of bio-derived alcohols which is unmatchable to conventional resins …

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The Proofreading Activity Of Pfprex From Plasmodium Falciparum Can Prevent Mutagenesis Of The Apicoplast Genome By Oxidized Nucleotides, Minakshi Sharma, Naveen Narayanan, Deepak T. Nair Dec 2020

The Proofreading Activity Of Pfprex From Plasmodium Falciparum Can Prevent Mutagenesis Of The Apicoplast Genome By Oxidized Nucleotides, Minakshi Sharma, Naveen Narayanan, Deepak T. Nair

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The DNA polymerase module of the Pfprex enzyme (PfpPol) is responsible for duplication of the genome of the apicoplast organelle in the malaria parasite. We show that PfpPol can misincorporate oxidized nucleotides such as 8oxodGTP opposite dA. This event gives rise to transversion mutations that are known to lead to adverse physiological outcomes. The apicoplast genome is particularly vulnerable to the harmful effects of 8oxodGTP due to very high AT content (~ 87%). We show that the proofreading activity of PfpPol has the unique ability to remove the oxidized nucleotide from the primer terminus. Due to this property, the proofreading …

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Enhanced Cell Density Cultivation And Rapid Expression-Screening Of Recombinant Pichia Pastoris Clones In Microscale, Neha Kaushik, Urpo Lamminmäki, Navin Khanna, Gaurav Batra Dec 2020

Enhanced Cell Density Cultivation And Rapid Expression-Screening Of Recombinant Pichia Pastoris Clones In Microscale, Neha Kaushik, Urpo Lamminmäki, Navin Khanna, Gaurav Batra

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Cultivation of yeast Pichia pastoris in the microtiter plate, for optimisation of culture conditions, and expression screening of transformants has gained significance in recent years. However, in the microtiter plate, it has been challenging to attain cell densities similar to well-aerated shake-flask culture, due to the poor mixing resulting in oxygen limitation. To solve this problem, we investigated the influence of multiple cultivation parameters on P. pastoris cell growth, including the architecture of 96-deepwell plate (96-DWP), shaking throw diameter, shaking frequency, culture volume/well, and media composition. In the optimised conditions, a cell density of OD600 ~50 (dry cell weight ~13 …

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Are Our Teachers Knowledgeable Towards Pre Hospital Emergency Care: A Study From South India, Alok Jindal, Ramesh Holla, Noorelle Karim Khan, Sukanya Basak Dec 2020

Are Our Teachers Knowledgeable Towards Pre Hospital Emergency Care: A Study From South India, Alok Jindal, Ramesh Holla, Noorelle Karim Khan, Sukanya Basak

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Background: School children stay a significant hour of the day in their school and are the medium through which information can be carried to their parents and other family members, about basic information regarding Pre-Hospital Care. Objectives: To determine the awareness about Pre-Hospital care among school teachers in Mangalore and to determine how many teachers have received formal training in Pre-Hospital care. Methods: A descriptive cross-sectional study conducted among school teachers in 5 schools across Mangalore. Convenience sampling was done. Data was obtained from 118 school teachers across five schools in Mangalore, India using a self-administered questionnaire. Results: It was …

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Stress Among The Caregivers Of Mentally Disabled Children Visiting A Rehabilitation Centre In Chennai, Tamil Nadu – A Cross-Sectional Study, Aarthi Ramachandran, Navya Vyas, Dan Isaac Pothiyil Dec 2020

Stress Among The Caregivers Of Mentally Disabled Children Visiting A Rehabilitation Centre In Chennai, Tamil Nadu – A Cross-Sectional Study, Aarthi Ramachandran, Navya Vyas, Dan Isaac Pothiyil

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Caregiving is a complex health care activity, from an informal family level activity; it is becoming a major part of health care. In India, family members are mostly caregivers for persons with mental disabilities. The present study assessed the stress among the caregivers of mentally disabled children (Autistic Spectrum Disorder, Intellectual Disability, and Attention Deficit Hyperactivity Disorder) and found the association between stress and selected socio-demographic variables. This was an institutional based cross-sectional study with a duration of six months, i.e. from January 2019 to June 2019. This study was conducted among the caregivers availing services (therapies and follow-ups) at …

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Effect Of Aerobic Exercises On Depressive Symptoms, Anxiety, Self-Esteem, And Quality Of Life Among Adults With Depression, Udatha Thirupathi Rao, Judith Angelitta Noronha, Kasturi Adiga Dec 2020

Effect Of Aerobic Exercises On Depressive Symptoms, Anxiety, Self-Esteem, And Quality Of Life Among Adults With Depression, Udatha Thirupathi Rao, Judith Angelitta Noronha, Kasturi Adiga

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Depression impacts on daily living activities of depressive patients. Patients suffering with mental disorders also show impairment in their Quality of life. Objective: To evaluate the effectiveness of aerobic exercises on depressive symptoms, anxiety, self-esteem, and quality of life among adults suffering from depression. Methods: Participants (N = 80) were assigned to the experimental group (40), received the aerobic exercises along with medication and control group (40), received the medication only. The intervention was carried out over a period of 8 weeks with the intervention group performing the exercise for 3 days a week. Results: The mean age of the …

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The Relationship Between Physical Fitness Qualities And Sport-Specific Technical Skills In Female, Team-Based Ball Players: A Systematic Review, Jessica B. Farley, Joshua Stein, Justin W.L. Keogh, Carl T. Woods Dec 2020

The Relationship Between Physical Fitness Qualities And Sport-Specific Technical Skills In Female, Team-Based Ball Players: A Systematic Review, Jessica B. Farley, Joshua Stein, Justin W.L. Keogh, Carl T. Woods

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Background: Understanding the relationships between physical fitness attributes and sport-specific technical skills may assist with the establishment of beneficial training interventions. The aim of this systematic review was to determine if physical fitness qualities were associated with performance of sport-specific technical skills in female, team-based ball players. Methods: Five databases (MEDLINE, EMBASE, SPORTDiscus, ProQuest, and Scopus) were searched for relevant studies up to April 15, 2019. Full-text articles investigating relationships between physical fitness and sport-specific technical skills in female, team-based ball players were included. Methodological quality of included studies was appraised using a modified Downs and Black checklist. Data synthesis …

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