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Perceived Medical, Social, And Psychological Issues Due To The Covid-19 Pandemic Among Elderly: A Descriptive Analysis, Khushboo Juneja, Kathan Kapoor, Ashwini Kumar, Kundangar Eshwari

Open Access archive

Elderly individuals are more likely to suffer from both short and long-term consequences of COVID19, including exacerbation of existing illnesses, psychological issues, and increased risk of death. This study aimed to understand the medical, perceived psychological, and social health problems faced by the elderly due to the COVID-19 pandemic. This hospital-based study included 225 elderly patients (aged ≥60 years) with chronic health conditions. Hypertension (70.2%) and diabetes mellitus (64.0%) were the most common morbidities among the study participants. At least 34.7% of the participants had one or more symptoms suggestive of psychological problems due to COVID-19 pandemic. Among the participants, …

Sentience And The Moral Status Of Animals: A Review Of Peter Godfrey-Smith's Trilogy, Andrew Rowan

Tales of WellBeing

Explore Peter Godfrey-Smith’s groundbreaking views on animal sentience and consciousness.

Animal Agriculture: Reversing Confinement Trends, Andrew Rowan

Tales of WellBeing

Learn how early 21st-century animal welfare campaigns targeted intensive confinement, leading to major changes in farmed animal treatment.

A 72-Year-Old Man With Acute Lung Injury And Anti-Melanoma Differentiation-Associated Gene 5 Antibody: A Case Report, Irakli Lemonjava, Jose Manuel Martinez Manzano, Sahar Sultan, Rekha Bhat, Corrado Minimo, Zurab Azmaiparashvili, Sadia Benzaquen

Einstein Health Papers

Anti-melanoma differentiation-associated gene 5 antibody (anti-MDA-5 Ab) is associated with amyopathic dermatomyositis (DM). These patients are particularly at high-risk for developing acute and rapidly progressive interstitial lung disease (ILD). Given the lack of muscle-related symptoms, along with its sudden onset and rapid clinical progression, the diagnosis of anti-MDA-5 Ab + ILD represents a challenge for clinicians. Even after the diagnosis is established, prognosis remains dismal owing to a hyperinflammatory state, mimicking cytokine storm, commonly refractory to potent immunosuppressive therapy. Hence, we present an elderly African American man who developed acute and rapidly progressive ILD in the setting of positive anti-MDA5 …

Fieldnote 18: Welcome Back!, Venus Evans-Winters Dr.

Fieldnotes of a Black Woman Scholar: Research, Culture, and Wellness

"Post" Pandemic Welcome Back! Dr. V discusses her journey over the last months and years after deciding to reclaim rest. She provides insights into her commitment to Collective Healing, Learning, and Laboring. Listen to learn some of the strategies she implemented as a professor, clinician, and solo-entrepreneur to bounce back from the pandemic and heal in the midst of it all.

Dataset For Effects Of Outdoor Recreation On Multiple Vertebrate Guilds In A Fragmented Sagebrush-Steppe Ecosystem (2019-2021), Madeline C. Aberg, Stephanie E. Coates, Lucian J. Davis, Benjamin W. Wright, Richard L. Mervin, Jay D. Carlisle

Biological Sciences Data

Outdoor recreational use is growing rapidly in the western United States, which increases the pressure on multiple-use public lands. Balancing recreational use with conservation goals requires considering the spatial and temporal intensity of recreational use and examining its effects on multiple species within an ecosystem. In 2019–2021, we assessed the relationship between recreational intensity and the abundance of a dominant prey species (Piute ground squirrel [Urocitellus mollis]), the abundance of avian and mammalian facultative scavengers that rely on ground squirrels, and the abundance and nesting success of ground-nesting birds at a national conservation area in southwestern Idaho, USA, where recreational …

Dataset For Effects Of Aging On Patellofemoral Joint Stress During Stair Negotiation On Challenging Surfaces, Nicholas L. Hunt, Amy E. Holcomb, Clare K. Fitzpatrick, Tyler N. Brown

Center for Orthopaedic and Biomechanics Research Data Repository

Patellofemoral joint (PFJ) pain is an incessant musculoskeletal disorder underreported in older adults. This study examined the effect of age and surface on the magnitude and waveform of PFJ stress during a stair ascent task. 12 healthy young adults and 12 healthy older adults completed a stair ascent and descent task on a normal, uneven, and slick surface. During stair ascent age impacted PFJ stress waveform (p < 0.001), but not magnitude, as older adults exhibited greater PFJ stress from 55 to 59% and 74 to 84% of stance (p < 0.037). The increase in older adults PFJ stress late in stance may be attributed to a later peak PFJ stress (p = 0.002) and larger PFJ stress-time integral (p = 0.003) than young adults. Surface also impacted PFJ waveform (p < 0.001). On the uneven surface during stair ascent, PFJ stress was smaller from 9 to 24%, but greater from 75 to 88% of stance (both: p < 0.001), and PFJ stress-time integral (p = 0.010) was greater than normal surface. A significant age by surface interaction was observed for time of peak PFJ stress (p = 0.041). On the uneven surface, older adults exhibited a later peak PFJ stress compared to young adults (p = 0.008), and later peak PFJ stress compared to normal and slick surface (both: p = 0.014). For stair descent, age impacted PFJ contact area range (p = 0.034) and peak knee flexion angle (= 0.022), but no other PFJ stress measure. On the uneven surface during stair descent, partipicants exhibited greater PFJ stress-time integral, reaction force impulse, and mean contact area (all: p < 0.05) compared to the slick surface. Surface also impacted PFJ stress waveform during stair descent, where participants exhibited greater stress from 0 to 16% of stance but smaller stress from 98 to 100% of stance on the uneven compared to slick surfaces. Older adults may be more likely to develop PFJ pain, as they exhibited larger and later PFJ stress, particularly when navigating an uneven surface. When navigating the uneven surface, all participants exhibited knee biomechanics, including larger PFJ stress in terminal stance and greater PFJ stress-time integral that may increase overall joint stress and increases risk of developing PFJ pain.

Pancreaticoduodenectomy After Endoscopic Ultrasound-Guided Lumen Apposing Metal Stent (Lams): A Case Series Evaluating Feasibility And Short-Term Outcomes: Whipple After Lumen Apposing Metal Stent, Luke Meredith, David Baek, Alisha Agarwal, Faisal Kamal, Anand R. Kumar, Alexander Schlachterman, Thomas E. Kowalski, Charles J. Yeo, Harish Lavu, Avinoam Nevler, Wilbur B. Bowne

Department of Surgery Faculty Papers

Introduction

Endoscopic ultrasound (EUS)-guided lumen-apposing metal stents (LAMS) represent a novel tool in therapeutic endoscopy. However, the presence of LAMS may dissuade surgeons from operations with curative-intent. We report three clinical scenarios with deployment of LAMS in patients that subsequently underwent pancreaticoduodenectomy (PD).

Methods

Six patients identified from our IRB-approved pancreas cancer database had EUS-LAMS placement prior to PD. Patient, tumor, treatment-related variables, and outcomes are herein reported.

Results

Two patients underwent a LAMS gastrojejunostomy (GJ) for duodenal obstruction. Another patient underwent LAMS choledochoduodenostomy (CDS) for malignant biliary obstruction. In three patients, a LAMS gastrogastrostomy or jejunogastrostomy was deployed post …

Data From: Sheared Turbulent Flows And Wake Dynamics Of An Idled Floating Tidal Turbine, Lilian Lieber, Alex Nimmo Smith

Faculty of Science and Engineering Datasets

Input data (minimally processed ADCP Matlab files) used to generate this study's results. The data is divided into two folders: 1) Broad-scale Transects and 2) Fine-scale Transects and 3), a README file is provided.

The Use Of Near-Infrared Angiography In Evaluating Bowel Anastomosis During A Gynecologic Oncology Surgery, Lea A. Moukarzel, Sarah Andres, Oliver Zivanovic

Abington Jefferson Health Papers

Reducing anastomotic leak rates after bowel resection is a priority among patients undergoing gynecologic oncology surgery. While near-infrared (NIR) angiography has been investigated in the colorectal literature, more recent work has demonstrated promising results when used in gynecologic cancer surgery. It has been repeatedly shown to be a safe intervention that can offer real time assessment of bowel perfusion, offering the surgeon the opportunity to act on the results in the hopes of decreasing the risk of complications.

Digital Ethics Of Artificial Intelligence (Ai) In Saudi Arabia And United Arab Emirates, Ella Gorian, Noor Dzuhaidah Osman

Open Access archive

Artificial intelligence (AI) poses a serious challenge for data protection and ethics. Whereas ethics is based on the moral and religious understanding of good and evil, adherence to religious norms is vital for many nations. In Islam, privacy is a fundamental value that is deeply rooted in the principles of Shariah law and focuses on the dignity of the individual, personal boundaries and moral behaviour. Therefore, the use of AI technologies by Islamic nations raises concerns about the compatibility of these traditional privacy norms with ethical frameworks for AI. To ensure that the field of AI is not only innovative …

Multi-Objective Optimization Of Sfc Deployment Using Service Aggregation And Computing Offload, Junbi Xiao, Jiaqi Zheng, Wu Wen, Mohsen Guizani, Peiying Zhang, Lizhuang Tan

Machine Learning Faculty Publications

New technologies such as virtualization and Software Defined Networking (SDN) have given traditional networks unprecedented flexibility. A Service Function Chain (SFC) formed by concatenating multiple Virtual Network Functions (VNFs) expands network functions to meet the growing personalized network requirements of applications. However, due to the decentralization of VNF instances and the tight cloud load, how to ensure Quality of Service (Qos) while deploying the SFC brings new challenges. Hence, a SFC deployment strategy based on multi-objective optimization, named MO-SACO is proposed, which regards delay optimization, reliability assurance and cost reduction as the main objectives. Specifically, we first design a VNF …

379. Sglt Inhibitors: The Biology Of Sglt Inhibition With Dr. Katherine Tuttle, Katherine Tuttle

Articles, Abstracts, and Reports

No abstract provided.

Horizons-Easd Elearning, Katherine Tuttle

Articles, Abstracts, and Reports

No abstract provided.

The Prepared Bystanders : A Social Impact Campaign, Sophia Cull

Postgraduate

1,272 people died on Australian roads in 2023 (BITRE, 2024). The Government’s 2021-30 Road Safety Strategy is to reduce the annual count to 571 (Commonwealth of Australia, 2021). No less than 1,000 people have died each year since 1935.

The Influence Of Emotional Intelligence And Behavioural Biases On Mutual Fund Churning Frequency: Evidence From India, R. Annapurna, Savitha Basri

Open Access archive

Behavioural finance invalidates the rationalistic assumptions of the efficient market hypothesis by proposing a realistic explanation for overreaction and underreaction. These phenomena are caused by investors making financial decisions based on their emotions without realizing them. This study attempts to establish the effect of investors' emotional intelligence on behavioural biases, namely, herding, overconfidence bias, and disposition effects, and its consequences for the churning frequency of mutual fund portfolios. This quantitative cross-sectional study was undertaken to collect data from 499 mutual fund investors using a self-administered questionnaire. We found that the disposition effect has a negative impact and that overconfidence bias …

Post Implementation Quarantine Recommendations That Support Preparedness: A Systematic Review And Quarantine Implementation Capability Framework, Matiu Bush, Catherine M. Bennett, Ana Hutchinson, Stéphane L. Bouchoucha

Open Access archive

Background: During COVID-19, countries utilised various quarantine systems to achieve specific outcomes. At different stages and durations, voluntary and mandatory quarantine occurred in homes, hotels and facilities based on local and national elimination strategies. Countries are incorporating quarantine lessons from COVID-19 into revising pandemic plans as part of the World Health Organization's Preparedness and Resilience for Emerging Threats (PRET) activities. This review aimed to amalgamate quarantine post implementation recommendations from a whole-of-system perspective. Methods: This review utilised MEDLINE, Embase, CINAHL, APA, and PsycINFO. To capture all pandemics, no date restriction was applied. Recommendations were synthesised and inductively grouped into quarantine …

Panniculitis And Diffuse Papulonecrotic Skin Lesions In A Paediatric Covid-19 Patient – A Case Report, Y. Ramesh Bhat, Jonnala Chaitanya Reddy

Open Access archive

The skin manifestations of COVID-19 are infrequent but vary widely. Maculopapular rash, urticaria, chilblain, vesicular lesions, livedo reticularis, and petechiae are described. The manifestations are also common in adults and female gender. Authors report an uncommon skin manifestation of Covid-19 in a 15-year-old boy.

Sodium Iodide Dopant Mediated Enhancements In Energy Storage Characteristics Of Polysaccharide Polymer Electrolytes, Supriya K. Shetty, Ismayil, Pradeep Nayak, Y. N. Sudhakar

Open Access archive

Sodium iodide dopant influencing the properties of polysaccharide polymer sodium carboxymethyl cellulose is analyzed in this work by FTIR, XRD, DSC, TGA, SEM, UTM, and electrical. Solvation of I⁻ and Na⁺ ions by the −OH group has disrupted the intra– and intermolecular hydrogen bonds between the polymers escorting to a decrease in crystallinity and creating a pathway for ion diffusion. The formation of transient crosslink and the physical environment created by the polymer-ion interaction have affected the rigidity of the polymer chains as well as the thermal stability of the NaCMC−NaI system. I⁻ ion influences the ESW …

Nano-Drug Carriers For Targeted Therapeutic Approaches In Oral Cancer: A Systematic Review, Vivekanand Kattimani, Nom Kumar Naik Bhukya, Gnana Sarita Kumari Panga, Abhisikta Chakrabarty

Open Access archive

Introduction: Nanotechnology has shown potential in treating different types of cancers. In particular, nano-drug delivery systems (DDSs) offer a promising strategy for treating oral cancer. By customizing therapy and improving drug delivery, these systems can improve outcomes for patients. Hence, a review was conducted to assess the current evidence and explore the use of DDSs for treating oral cancer. Aim: To comprehensively explore the nano-drug carriers and target delivery for oral cancer therapy and to discuss the benefits, challenges, and potential to guide future research and clinical practice. Methodology: A systematic search of articles archived in PubMed, Scopus, and Cochrane …

E-Learning Strategies Implemented By Instructors For Individuals With Hearing Impairment, Sherin Joy, Archana Gundmi

Open Access archive

The current study aims at exploring the strategies used by instructors to deal with e-learning of individuals with hearing impairment and identifying barriers encountered by instructors of individuals with hearing impairment through a telephonic interview. A set of validated probes was created, and a semi structured interview was conducted with 12 instructors who teach individuals with hearing impairment. The obtained data was subjected to inductive content analysis. Two major themes emerged from the data; challenges encountered by instructors and strategies adopted by instructors. Several subthemes and codes were grouped under each theme. Overall, the study indicated the need for extensive …

Characteristics Of The Copd Patients For The Implementation Of The Smartphone Application For The Copd: An Implementation Study, Ashwani Verma, Ashok Behera, N. Ravishankar, Monirul Islam

Open Access archive

Background: This study provides us an opportunity to discuss about the development of a smartphone enabled Home based Self-management application for Chronic Obstructive Pulmonary Disease. Objective: To summarize the baseline characteristics of the Chronic Obstructive Pulmonary Disease patients recruited in present study. Methods: A single centered prospective non-randomized study has been conducted to implement the selfmanagement application among 166 patients. Patients were matched based on gender and Global Initiative for Obstructive Lung Disease criteria. Smartphone application was provided to the intervention group and instructions were given to them. Results: The mean age of participants was 58.02 years in which more …

Nonlinear Optical Properties Of Zinc Oxide Thin Films, A. Ayana, Neelamma B. Gummagol, Parutagouda Shankaragouda Patil, P. Sharma

Open Access archive

This study reports the influence of deposition temperature (573 K-773 K) on the microstructural, linear and nonlinear optical properties of zinc oxide nano thin films synthesized using the chemical spray pyrolysis method. Synthesized films are polycrystalline, exhibiting a dominant (1 0 1) orientation, for which the crystallite size is found to increase with deposition temperature up to 723 K followed by a decrease. Concurrently, the deposit prepared at 723 K showed improved electrical properties, i.e. higher charge carrier concentration and mobility. Optical studies reveal increased transmittance in the visible region and a gradual increase of optical bandgap with deposition temperature. …

In-Situ Synthesis Of Quaternary Alkylammonium Ligand Capped Organic-Inorganic Hybrid Halide Perovskite For High Pure Green Luminescence In Display Application, Maithili K. Rao, Selvaraj Paramasivam, M. Selvakumar, M. S. Santosh

Open Access archive

This study delves into the intricate dynamics of ligand engineering for the synthesis of Methyl Ammonium Lead Bromide (MAPbBr3) nanocrystals (NCs), which exhibit immense potential in optoelectronic and photovoltaic applications. Our focus centres on the role of the quaternary ammonium molecule CTAB as a ligand in stabilizing MAPbBr3 NCs. This also addresses the challenges related to the stability and surface defects of NCs that hinder their commercial viability. Employing a modified ligand-assisted reprecipitation technique (LARP) with a dual solvent system, we optimized the CTAB concentration to 0.05 mmol, resulting in MAPbBr3 NCs with an impressive 88% quantum yield. XPS and …

Unveiling Highly Sensitive Dy3+ Doped Bamgal10o17 Phosphor’S Thermoluminescence Trap Features And Temperature Dependent Luminescence For Solid State Lighting Applications, A. Vidya Saraswathi, Tejas Chennappa, Karunakara Naregundi, A. Princy

Open Access archive

This article explores the structural, morphological, thermoluminescence, and temperature-dependent emission properties of novel Dy³⁺ doped BaMgAl10O17(BAM-Dy) phosphors. Structural studies reveal that the phosphor has a similar structure to β-alumina. Rod-shaped interlinked surface morphology is a notable characteristic of the BAM-Dy samples. Incorporation of Dy³⁺ ions lead to the formation of distinct emission peaks (485 nm, 577 nm, and 635 nm) in the PL emission spectra. The effect of dopant concentration on the light output is crucial, and the highest PL intensity is observed for 1.5 mol% of Dy³⁺ concentration. The potential use of BAM-Dy phosphors for Gamma …

Elucidation Of Trap Energies Of Gamma-Irradiated Bamgal10o17: Ce3+ Phosphors For Dosimetry Applications, A. Vidya Saraswathi, Karunakara Naregundi, M. I. Sayyed, Nouf Almousa

Open Access archive

This paper presents a comprehensive examination of the thermoluminescence properties of BaMgAl10O17: Ce (BAM: Ce) phosphors, which were synthesized via the combustion method. The study employs five distinct approaches to determine the kinetic parameters for individual traps. To investigate the structural, morphological, and elemental composition of the samples, X-ray diffraction, scanning electron microscopy, and energy-dispersive X-ray spectroscopy were utilized. The photoluminescence spectra revealed a broad emission centered around 420 nm upon 330 nm excitation. By subjecting the phosphors to γ doses ranging from 5 to 5 kGy and conducting TL glow curve analysis, the kinetic characteristics of the BAM: Ce …

Genome Sequencing Enables Diagnosis And Treatment Of Slc5a6 Neuropathy, Lisa G. Riley, Subrata Sabui, Hamid M. Said, Aram Niaz

Open Access archive

The sodium-dependent multivitamin transporter encoded by SLC5A6 is responsible for uptake of biotin, pantothenic acid, and α-lipoic acid. Thirteen individuals from eight families are reported with pathogenic biallelic SLC5A6 variants. Phenotype ranges from multisystem metabolic disorder to childhood-onset peripheral motor neuropathy. We report three additional affected individuals with biallelic SLC5A6 variants. In Family A, a male proband (AII:1) presenting in early childhood with gross motor regression, motor axonal neuropathy, recurrent cytopenia and infections, and failure to thrive was diagnosed at 12 years of age via genome sequencing (GS) with a paternal NM_021095.4:c.393+2T>C variant and a maternal c.1285A>G p.(Ser429Gly) …

Grapevine Bud Mirnas Under Long And Short Photoperiods, R. Kaur

Agronomy, Horticulture and Plant Science Dataset Collection

This data set includes microRNA sequences from 2 F2 genotypes (VRS-F2-110 and VRS-F2-040) that wer subjected to long day or short day treatments after reaching 10 nodes.

File Type : xls
File size: 42 MB

Strategy To Improve The Oral Pharmacokinetics Of Cyclin-Dependent Kinase 4/6 Inhibitors: Enhancing Permeability And Cyp450 Inhibition By A Natural Bioenhancer, Prajakta Harish Patil, Mrunal Pradeep Desai, Rajat Radhakrishna Rao, Srinivas Mutalik

Open Access archive

Palbociclib and ribociclib an orally bioavailable, potent cyclin-dependent kinase 4/6 inhibitors, with low oral bioavailability due to substrate specificity towards CYP3A and P-glycoprotein. Thus, current research aims to examine the effect of a bioenhancer (naringin), on oral pharmacokinetics of palbociclib and ribociclib. Naringin’s affinity for CYP3A4 and P-glycoprotein was studied using molecular docking; its impact on palbociclib/ribociclib CYP3A metabolism and P-glycoprotein-mediated efflux was examined using in vitro preclinical models; and its oral pharmacokinetics in rats were assessed following oral administration of palbociclib/ribociclib in presence of naringin (50 and 100 mg/kg). Naringin binds optimally to both proteins with the highest net …

Utilization Of Alkali-Treated Areca Fibers For Stabilizing Silty Sand Soil For Use In Pavement Subgrades: Analysis Using Iitpave Software, Muttana S. Balreddy, Sanjay S. Sajjan, Dayananda Pruthviraja, Sujay Raghavendra Naganna

Open Access archive

The increasing growth of urban areas and the rise in infrastructure development activities have put a strain on the availability of land with desirable soil conditions. This has led to the development of several stabilization techniques that can be used to improve the properties of weaker soils for construction. The research presented here explores the impact of inducing randomly oriented alkali-treated areca fibers for stabilization of silty sand soil. A sequence of experiments was carried out on the soil-fiber mixtures to investigate the strength of the soil after stabilization. At increments of 0.2%, the fiber dose varied between 0 – …