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Exploiting Structural Differences Among Heteroduplex Molecules To Simplify Genotyping The Dqa1 And Dqb1 Alleles In Human Lymphocyte Typing, Peter A. Zimmerman, Mary Carrington, Thomas B. Nutman Jan 1993

Exploiting Structural Differences Among Heteroduplex Molecules To Simplify Genotyping The Dqa1 And Dqb1 Alleles In Human Lymphocyte Typing, Peter A. Zimmerman, Mary Carrington, Thomas B. Nutman

United States Public Health Resources

A novel approach to DNA probe hybridization and heteroduplex analysis, termed directed heteroduplex analysis (DHDA) is presented here to illustrate its utility in simplification of human lymphocyte antigen (HLA)- typing. By strategic labeling of single-stranded probe sequences, DHDA allows the identification of specific heteroduplex structures that contribute to the differentiation of DQAI and DQB1 alleles. Because of the high degree of polymorphism among major histocompatibility complex class 11 second exon sequences, this analysis of 50 different heteroduplex molecules provides evidence of the importance of unpaired bases and mismatched base pairs and their effect on heteroduplex electrophoretic-mobility differences. This strategy is …


The Development Of Microbicides: A New Method Of Hiv Prevention For Women, Christopher J. Elias, Lori L. Heise Jan 1993

The Development Of Microbicides: A New Method Of Hiv Prevention For Women, Christopher J. Elias, Lori L. Heise

HIV and AIDS

A critical review of current epidemiological trends and social science research demonstrates that there is an urgent need for expanding the range of female-controlled HIV prevention methods. Existing efforts to control the spread of HIV infection primarily through the encouragement of a reduction in the number of sexual partners, widespread condom promotion, and the control of other sexually transmitted infections are inadequate for many of the world's women. Underlying gender power inequities severely limit the ability of many women to protect themselves from HIV infection, especially in the absence of a prevention technology they can use, when necessary, without their …


Community-Based Aids Prevention And Care In Africa: Workshop Report, Andrea Eschen Jan 1993

Community-Based Aids Prevention And Care In Africa: Workshop Report, Andrea Eschen

HIV and AIDS

Representatives from community-based AIDS prevention and care programs in five sub-Saharan African countries spoke about their programs’ strengths, shortcomings, and hopes for the future at a meeting organized by the Population Council that took place on June 5, 1993, in Berlin just prior to the IXth International Conference on AIDS. Participants’ experiences and insights demonstrated the ingenuity and imagination that communities have generated to prevent the spread of HIV and AIDS and how they have taken action where government activities have fallen short. The workshop brought representatives of these programs together with staff of governmental and nongovernmental organizations, funding institutions, …


Oral Contraceptives And Reproductive Cancers: Weighing The Risks And Benefits, Ann L. Coker, Susan Harlap, Judith A. Fortney Jan 1993

Oral Contraceptives And Reproductive Cancers: Weighing The Risks And Benefits, Ann L. Coker, Susan Harlap, Judith A. Fortney

CRVAW Faculty Journal Articles

The hypothetical incidence of reproductive cancers resulting from oral contraceptive use was estimated in several models comparing the cumulative lifetime incidence of cancer of the breast, cervix, ovary and endometrium expected in pill users with the incidence expected in nonusers. The potential number of cancer-free days that would be gained or lost by pill users was com- pared with similar estimates among nonusers. If five years or more of pill use were associated with a 20% increase in the risk of breast cancerbeing diagnosed before age 50, a 20% increase in cervical cancer risk and a 50% reduction in the …


Pus, Pox, Propaganda And Progress: The Compulsory Smallpox Vaccination Controversy In Utah, 1899-1901, Eric L. Bluth Jan 1993

Pus, Pox, Propaganda And Progress: The Compulsory Smallpox Vaccination Controversy In Utah, 1899-1901, Eric L. Bluth

Theses and Dissertations

This thesis examines the compulsory smallpox vaccination controversy in Utah, 1899-1901. It looks at the two smallpox epidemics during 1899-1901 and follows the boards of health attempts to eradicate smallpox primarily by compelling the vaccination of school children.

Dr. Theodore B. Beatty, secretary of the State Board of Health, championed the effort to vaccinate all Utahns; however, the opposition led by Charles W. Penrose, editor of the Deseret Evening News, produced anti-compulsion and vaccination information which influenced Utahns to generally oppose vaccination. Consequently, the legislature passed an anti-compulsory vaccination statute over the governor's veto to annul the courts decision …


Monitoring Of Fungal Spores In An Experimental Indoor Environment To Evaluate Sampling Methods And The Effects Of Human Activity On Air Sampling, Mark P. Buttner, Linda Stetzenbach Jan 1993

Monitoring Of Fungal Spores In An Experimental Indoor Environment To Evaluate Sampling Methods And The Effects Of Human Activity On Air Sampling, Mark P. Buttner, Linda Stetzenbach

Environmental & Global Health Faculty Research

Aerobiological monitoring was conducted in an experimental room to aid in the development of standardized sampling protocols for airborne microorganisms in the indoor environment. The objectives of this research were to evaluate the relative efficiencies of selected sampling methods for the retrieval of airborne fungal spores and to determine the effect of human activity on air sampling. Dry aerosols containing known concentrations of Penicillium chrysogenum spores were generated, and air samples were taken by using Andersen six-stage, Surface Air System, Burkard, and depositional samplers. The Andersen and Burkard samplers retrieved the highest numbers of spores compared with the measurement standard, …


Gente Joven/Young People: A Dialogue On Sexuality With Adolescents In Mexico, Magaly Marques, John M. Paxman, Judith Bruce Jan 1993

Gente Joven/Young People: A Dialogue On Sexuality With Adolescents In Mexico, Magaly Marques, John M. Paxman, Judith Bruce

Poverty, Gender, and Youth

This issue of Quality/Calidad/Qualité describes the experience of one adolescent sexuality program, Gente Joven in Mexico. Gente Joven began by acknowledging reality: that the problems related to teenage sexuality will not go away simply by denying their existence. Along the way Gente Joven learned, and is continuing to learn, many lessons about how to build a successful program for adolescents. Here they share their experiences and the Afterword explores in greater depth one particular issue that Gente Joven has identified as its next major challenge: re-examining their work with young people from a gender perspective.


Findings From Two Decades Of Family Planning Research, John A. Ross, Elizabeth Frankenberg Jan 1993

Findings From Two Decades Of Family Planning Research, John A. Ross, Elizabeth Frankenberg

Poverty, Gender, and Youth

This book presents a selection of empirical conclusions, or findings, from the body of family planning research that has accumulated over the last two decades. Twelve topics of current interest are reviewed, as a sequel to three similar publications issued in 1971, 1972, and 1974. A findings document compresses what has been learned into straightforward declarative statements, giving summary evidence to support each statement. In cases where a conclusion is well founded, with extensive supporting evidence, only illustrative or summary references are needed. In other cases, citations are required for individual studies. Generalizations that are unsupported or too ambiguous to …


Family Planning And Population: A Compendium Of International Statistics, John A. Ross, W. Parker Mauldin, Vincent C. Miller Jan 1993

Family Planning And Population: A Compendium Of International Statistics, John A. Ross, W. Parker Mauldin, Vincent C. Miller

Poverty, Gender, and Youth

This volume provides statistics on all large-scale family planning (FP) programs in the developing world, together with selected demographic and socioeconomic statistics. Time trends are given for some indicators, and data are arranged for comparative analysis across countries. Where available, time trends go back to the mid-1980s. This volume’s predecessor, published in 1992, should be consulted for earlier demographic and socioeconomic data, and for tables on maternal and child health indicators that are not repeated here. The data on FP programs come from a series of three questionnaires sent since 1987 to 100 developing countries, which have generally been kept …


Fertility, Family Size, And Structure: Consequences For Families And Children, Cynthia B. Lloyd Jan 1993

Fertility, Family Size, And Structure: Consequences For Families And Children, Cynthia B. Lloyd

Poverty, Gender, and Youth

In 1989 the Population Council began a research project on the consequences of high fertility at the family level and its implications for the next generation. Since its inception, the project has been supported by Swedish SIDA and has involved the collaboration of researchers from selected developing countries. In countries where there has been limited research on this topic, such as India, Mali, Nigeria, Pakistan, and Senegal, the Population Council provided funding for new studies or for analysis of existing data with the potential for producing insights on this topic. In instances where relevant research was already underway, the Council …


Wasteland Development And The Empowerment Of Women: The Sarthi Experience, Madhu Sarin Jan 1993

Wasteland Development And The Empowerment Of Women: The Sarthi Experience, Madhu Sarin

Poverty, Gender, and Youth

This issue of SEEDS describes an innovative approach to rehabilitation of wastelands developed by Social Action for Rural and Tribal Inhabitants of India (SARTHI), a nongovernmental organization based in the Panchmahals District of Gujarat State in Western India. By assisting rural women to organize themselves around the rehabilitation of patches of degraded common land, SARTHI has been able to help them not only meet their needs for biomass in a more efficient and ecologically sound manner, but also to empower them to start asserting themselves in dealing with a broader range of problems. As primary gatherers and users of biomass, …


Aménagement Des Terres Incultes Et Émancipation Des Femmes L'Expérience De Sarthi, Madhu Sarin Jan 1993

Aménagement Des Terres Incultes Et Émancipation Des Femmes L'Expérience De Sarthi, Madhu Sarin

Poverty, Gender, and Youth

Ce numéro de SEEDS est consacré a une approche innovative ayant pour but d’aménager des terres incultes, développée par Action Sociale en faveur des population rurales et autochtones d’lnde (SARTHI), une organisation non gouvernementale basée dans le district de Panchmahals dans l’État de Gujarat en Inde occidentale. En aidant les femmes rurales à s’organiser pour mettre en valeur des lopins de terres communaux, SARTHI a permis à ces femmes de satisfaire leurs besoins en biomasse de façon plus efficace et saine d’'un point de vue écologique et d’améliorer d’autres aspects de leur vie. Étant donné que ce sont essentiellement les …


Rethinking Postpartum Health Care, Martha Brady, Beverly Winikoff Jan 1993

Rethinking Postpartum Health Care, Martha Brady, Beverly Winikoff

Reproductive Health

These proceedings come from papers and discussions as part of the Population Council invitational seminar entited "Rethinking Postpartum Health Care," in 1992. The seminar on postpartum reproductive health was the fifth in a series of seminars convened by the Population Council as part of its Robert H. Ebert Program on Critical Issues in Reproductive Health and Population. The program focuses on four topics: 1) improving and devising new approaches to postpartum care; 2) improving the quality of care in family planning and reproductive health services; 3) managing unwanted pregnancy and preventing the consequences of unsafe abortion; and 4) bringing attention …


Employment-Based Family Planning Services, Placide Tapsoba, Ian Askew, J. Tunde Taylor Thomas, Sering Falu Njie, Momodou Jasseh Jan 1993

Employment-Based Family Planning Services, Placide Tapsoba, Ian Askew, J. Tunde Taylor Thomas, Sering Falu Njie, Momodou Jasseh

Reproductive Health

Although The Gambia Family Planning Association (GFPA) has always been interested in promoting contraceptive use in the Greater Banjul Area (GBA), insufficient funds and the need to prioritize program expansion in rural areas hindered this. The GFPA operates two clinics in GBA, open to few workers. The government has three Family Planning and Maternal and Child Health clinics in Banjul, also used by few workers. Factory managers, trade union leaders, and the GFPA believe that a well-organized family planning (FP) education and service delivery program could benefit employees and employers. This operations research study tested the feasibility of a work-based …


Review Of Existing Norplant® Acceptor Tracking System, Joedo Prihartono Jan 1993

Review Of Existing Norplant® Acceptor Tracking System, Joedo Prihartono

Reproductive Health

Family planning (FP) activities in Indonesia are considered a successful national program. Since its introduction in the 1970s, the total number of active contraceptive users dramatically increased to 21 million couples. The government continuously tries to improve the quality of FP services. New developments in contraceptives at the international level have been monitored to assess the possibility of their application in Indonesia, to broaden the variety of available contraceptives. Norplant® implants were introduced in 1981, and as of 1993 there were more than two million cumulative Norplant users in Indonesia. As a long-term progestin-only contraceptive, this method must be removed …


The 1992 Indonesia Norplant® Use-Dynamics Diagnostic Study, Dinan S. Bratakoesoema, Abdul Rodjak, Sulaiman Sastrawinata, Faisal R. Djamal, Hafni Bachtiar, Dr. Masrul, Nadra B. Azwar Jan 1993

The 1992 Indonesia Norplant® Use-Dynamics Diagnostic Study, Dinan S. Bratakoesoema, Abdul Rodjak, Sulaiman Sastrawinata, Faisal R. Djamal, Hafni Bachtiar, Dr. Masrul, Nadra B. Azwar

Reproductive Health

Although the Indonesian Norplant® program is unique in terms of scale and pace of expansion, it also characterizes many of the operational problems that other developing countries are likely to confront as they expand their Norplant programs. Many of the concerns—such as screening and counseling, use-effectiveness, removal on demand, and tracking and notification systems for five-year removal—can only be answered through research on the Indonesian program. As this report states, operations research on issues related to Norplant within the Indonesian program will be of direct relevance to the growing number of Norplant programs in other developing countries. While the Indonesian …


Computer Model For Predicting Aids Among Intravenous Drug Users, Daniel Berleant, R. Ron Goforth, Jun Yuan Jan 1993

Computer Model For Predicting Aids Among Intravenous Drug Users, Daniel Berleant, R. Ron Goforth, Jun Yuan

Journal of the Arkansas Academy of Science

Intravenous drug abuse (IVDA) is an important cause of HIV transmission. Computer simulation is one way to understand and predict the spread of HIV infection among IVDAs. We design and simulate HIV infection among IVDAs and the impact of AIDS on this community, and thereby predict future IVDA population, HIV levels, AIDS levels, and AIDS deaths in this group. The HIV to AIDS, and AIDS to Death latencies are described by probability density functions (PDFs) in this model. Factors such as the recruit, quit, and normal death rate of IVDAs, are considered, as well as the infection and removal rates …


Economic Impacts Of Noxious Facilities: Incorporating The Effects Of Risk Aversion, Leslie A. Nieves Jan 1993

Economic Impacts Of Noxious Facilities: Incorporating The Effects Of Risk Aversion, Leslie A. Nieves

RISK: Health, Safety & Environment (1990-2002)

The author suggests an integrative approach for projecting economic impacts of facilities that elicit public Risk aversion. She incorporates both economic stimulus effects and perception-based effects of facilities on the host area economy. Empirical findings are compared and an impact estimation framework is suggested for integrating psychometric and econometric techniques.


Health Care Reform In The United States, Lawrence O. Gostin Jan 1993

Health Care Reform In The United States, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

The author presents a brief description of the design features and objectives of the health care reform package, together with the reasons to support reform of the health care system in the United States.


Tabaco, Ambiente Y Salud. La Situación En Venezuela Y El Mundo, Aldemaro Romero Jr. Jan 1993

Tabaco, Ambiente Y Salud. La Situación En Venezuela Y El Mundo, Aldemaro Romero Jr.

Publications and Research

No abstract provided.


Health Care Beliefs Of Elderly Vietnamese Refugees, Gayle Watson Jan 1993

Health Care Beliefs Of Elderly Vietnamese Refugees, Gayle Watson

Theses : Honours

Since 1975, a large number of Vietnamese refugees have settled in Australia. They can be recognised as a distinct cultural group within our society. However, little research has focused upon the health practices and beliefs of these people. This is a study of elderly Vietnamese refugees who have previously been identified as maintaining a great adherence to traditional values and behaviours. The aim of the research is to describe the health practices and beliefs of elderly Vietnamese refugees. As a mini ethno-nursing study, this research sought qualitative data, guided by the Health Belief Model adapted to accommodate cultural perspectives. With …


The Relationship Of Locus-Of-Control And Altruism To Prehospital Emergency Medical Care Providers Universal Precaution Practices, Joanne L. Wakeham Jan 1993

The Relationship Of Locus-Of-Control And Altruism To Prehospital Emergency Medical Care Providers Universal Precaution Practices, Joanne L. Wakeham

Health Services Research Dissertations

The purpose of this study was to determine the relationship between locus of control, altruism, occupational risk, and personal factors to the frequency of universal precautions practices of prehospital emergency medical care providers. The effects of OSHA's Occupational Exposure to Bloodborne Pathogens; Final Rule on reducing prehospital emergency medical care providers occupational exposure to bloodborne pathogens were also examined. Prehospital emergency medical care providers from municipal and private EMS agencies in the Tidewater Emergency Medical Services region participated in this study. Prehospital emergency medical care providers self-reported perceptions of locus of control, altruism, occupational risk, and universal precautions practices were …


Mathematical Transmission Model Of The Spread Of Hiv Through Sexual Contact And Iv Drug Usage Among Heterosexuals In Western Australia, B. Glockner Jan 1993

Mathematical Transmission Model Of The Spread Of Hiv Through Sexual Contact And Iv Drug Usage Among Heterosexuals In Western Australia, B. Glockner

Theses : Honours

The human immunodeficiency virus (HIV) and its latter stage, the acquired immune deficiency syndrome (AIDS), are still a major health problem in the world and the full extent of the epidemic is unknown. The HIV virus in Australia has been spread mainly through homosexual contact, but this mode of transmission is decreasing while transmission from heterosexual contact and from IV drug use is increasing. The proposed mathematical model concentrates on transmission of the HIV virus through heterosexual contact and IV drug use among heterosexuals in Western Australia. The model parameters will be estimated from surveys conducted by the Australian National …


A Comparison Of Division I And Division Ii Student-Athletes' Backgrounds, Time Demands And Perceptions Of Academics And Athletics, Denise Reifel Jan 1993

A Comparison Of Division I And Division Ii Student-Athletes' Backgrounds, Time Demands And Perceptions Of Academics And Athletics, Denise Reifel

Masters Theses

No abstract provided.


Development Of A Physical Ability Test For Screening Mental Health Technician Trainee Candidates, Brett Andrew Dolezal Jan 1993

Development Of A Physical Ability Test For Screening Mental Health Technician Trainee Candidates, Brett Andrew Dolezal

Masters Theses

This study was designed to establish a valid physical ability test for use by the Illinois Department of Mental Health and Developmental Disabilities to screen job applicants for the position of Mental Health Technician Trainee. Physical ability tests to determine physical qualifications for jobs requiring substantial physical effort are permitted under current Equal Employment Opportunity Commission (EEOC) and Americans with Disabilities Act (ADA) guidelines if the required physical standards are job related and consistent with business necessity. In order to determine the physical demands encountered by Mental Health Technicians, a job analysis was conducted. The job analysis phase included: (i) …


Bilan De Santé Des Travailleurs Québécois, Michèle Gervais Jan 1993

Bilan De Santé Des Travailleurs Québécois, Michèle Gervais

Rapports de recherche scientifique

Cette étude de la santé des travailleurs a été faite à partir des données de l'enquête Santé Québec de 1987. Elle s'est principalement intéressée aux problèmes chroniques et aux incapacités, à leur évolution selon l'âge, à leur profil selon le sexe. Les principaux problèmes de santé sont identifiés et leur variation parfois étonnante commentée à la lumière du phénomène de l'autosélection.

Plusieurs analyses multivariées utilisant un bon nombre des variables fournies par l'enquête Santé Québec ont été tentées, sans résultat probant. Cette enquête de santé générale sur l'ensemble de la population -qui n'avait donc pas été conçue autour des conditions …


Efficacité Du Captage Des Fumées De Soudage Par Les Torches Aspirantes De Type Mig-Mag, Guy Perrault, Louis Lazure, Van Hiep Nguyen, Claude Létourneau Jan 1993

Efficacité Du Captage Des Fumées De Soudage Par Les Torches Aspirantes De Type Mig-Mag, Guy Perrault, Louis Lazure, Van Hiep Nguyen, Claude Létourneau

Rapports de recherche scientifique

Certaines torches de soudage de type MIG (metal inert gas) et MAG (metal active gas) sont équipées d'un système de captage à la source incorporé au pistolet afin de protéger les travailleurs. Des chercheurs suédois se sont intéressés à la performance de ces systèmes[1] [2] pour conclure à des possibilités d'amélioration par une série de modifications aux torches de conception commerciale (modification de la buse d'extraction, augmentation des débits d'aspiration, variation des pressions de succion, etc. ). Une étude récente[3] a décrit l'utilisation des gaz traceurs pour mesurer l'efficacité de captage. Toutefois, ces études …


Évaluation De Pompes Personnelles D'Échantillonnage, Rodrigue Gravel Jan 1993

Évaluation De Pompes Personnelles D'Échantillonnage, Rodrigue Gravel

Rapports de recherche scientifique

L'apparition sur le marché de plusieurs nouveaux modèles de pompes et les demandes régulières des intervenants du Réseau de la santé du travail nous ont conduits à l'étude de treize modèles différents de pompes à haut et bas débits.

Le document "Procédure d'évaluation de pompes personnelles d'échantillonnage" IRSST, Direction des Laboratoires, juin 1988 a servi de base pour la procédure d'évaluation.

Cinq points principaux ont été étudiés lors de l'évaluation : 1) la description générale de chaque modèle; 2) les critères généraux comprenant les caractères physiques, les composantes essentielles, les approbations sécuritaires et les garanties; 3) les critères mécaniques comprenant …


Atteintes Musculosquelettiques Reliées Au Travail Répétitif Dans Le Secteur Électrique, Marie St-Vincent, Denise Chicoine, Sylvie Beaugrand Jan 1993

Atteintes Musculosquelettiques Reliées Au Travail Répétitif Dans Le Secteur Électrique, Marie St-Vincent, Denise Chicoine, Sylvie Beaugrand

Rapports de recherche scientifique

Le projet origine d'une demande adressée à l'IRSST par l'Association paritaire pour la santé et la sécurité du travail - Secteur fabrication de produits en métal et produits électriques. La demande faisait suite à une enquête de perception effectuée par l'ASP auprès du secteur électrique. Cette enquête a montré que dans le secteur électrique, l'une des préoccupations majeures en santé-sécurité était les atteintes musculo-squelettiques reliées au travail répétitif.

Le secteur électrique regroupe quelque 24 460 travailleurs répartis dans environ 400 usines. Le secteur se caractérise par une grande hétérogénéité quant aux types de production des différentes usines. Avant d'entreprendre le …


Étude Des Accidents Mortels Et Graves Dans Le Bâtiment Et Les Travaux Publics, Georges Toulouse, Denise Chicoine, André Lan Jan 1993

Étude Des Accidents Mortels Et Graves Dans Le Bâtiment Et Les Travaux Publics, Georges Toulouse, Denise Chicoine, André Lan

Rapports de recherche scientifique

Dans le but de montrer l'importance d'une analyse plus approfondie des accidents dans construction, nous nous sommes fixés les objectifs suivants:

  • Apporter une meilleure compréhension du processus des accidents dans le secteur de la construction. Il s'agit plus particulièrement de situer l'accident dans le contexte du travail, en fonction de l'activité du travailleur et du fonctionnement de l'organisation.
  • Souligner certains problèmes de travail qui ont des conséquences importantes sur la sécurité. Ces problèmes peuvent être directement résolus par des mesures préventives ou nécessiter des recherches en ergonomie.

Les résultats de cette étude peuvent avoir différentes retombées:

  1. Susciter des recherches sur …