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Molecular And Serological Studies Of Recombinant Bluetongue Viruses., Jasbir Brar Kahlon

All ETDs from UAB

No abstract provided.

The Measurement Of Human Chorionic Gonadotropin For Pregnancy Testing, Carolyn S. Feldkamp, William H. Pfeffer

Henry Ford Hospital Medical Journal

/Among many measurable hormones, human chorionic gonadotropin (FICG) is commonly used for pregnancy testing because it is very sensitive and relatively specific. Pregnancy can be identified shortly after implantation. Because some reagents cross-react with luteinizing hormone (LH), the sensitivity of urine tests has been adjusted to maintain specificity. Radioreceptor assay s on serum are more sensitive than urine tests but similarly lack specificity. The problems of LH cross-reactivity are eliminated by antisera specific for the beta subunit. Quantitation of HCG provides additional information useful in diagnosing ectopic pregnancy, providing a prognosis in threatened abortion, and following neoplasms. Considerations of cost, …

Microbiological Water Quality Of Impoundments: A Literature Review, G. Allen Burton Jr.

United States Public Health Resources

Assessing the microbiological water quality of impoundments and the potential for waterborne disease outbreaks is a difficult task when using traditional sampling programs. Problems associated with using fecal coliform bacteria as indicators of human pathogen presence complicates assessments of future water quality in preimpoundment areas. Reliable determination of future and present microbiological water quality requires knowledge of how the chemical, physical, and biological characteristics of the watershed and impoundment interrelate to influence microbial indicator and pathogen densities. Accurate estimates of microbial indicator and pathogen densities, obtainable by using the enumeration methods and their modifications suggested in this report, will allow …

Natural History Of The Porcine Bioprosthetic Heart Valve, Donald J. Magilligan Jr., Joseph W. Lewis Jr., J. Lancelot Lester Iii, Paul D. Stein, Mohsin Alam, Jeffrey B. Lakier, Julio C. Davilia, David W. Smith

Henry Ford Hospital Medical Journal

The porcine bioprosthesis has been the prosthetic valve of choice at Henry Ford Hospital since October 1971. By 1979, 23 cases of degeneration had been seen, and the rate seven years after implantation was 16%. Now, with a ten-year follow-up, there are 41 degenerated valves. After seven years, the percent free of degeneration is 88%, (SE of 2% [standard error]); at eight years, 82% (SE of 2.9%,); at nine years, 80% (SE of 3.4%); and at ten years, the percent free of degeneration is 69% (SE of 6.5%,). There was no difference in degeneration between men and women, between aortic …

Immunological Involvement In Porcine Bioprosthetic Valve Degeneration: Preliminary Studies, Rollin H. Heinzerling, Paul D. Stein, Jeanne M. Riddle, Donald J. Magilligan Jr., John J. Jennings

Henry Ford Hospital Medical Journal

Preliminary animal model studies have indicated that porcine bioprosthetic valves can be recognized by the immune system. This report presents the results of a preliminary investigation on the implanted valves of 27 patients. While none of the 27 demonstrated an immune response to porcine serum proteins, five patients developed antibodies against the implanted valve leaflets. Cells were enzymatically eluted from a degenerated bioprosthetic valve and were classified by means of monoclonal antibodies. Although these cells were not found to be of T-lymphocyte lineage, they did express la determinants and had the morphologic appearance of plasma cells. We therefore conclude that …

The Surgeon And The Patient With Cancer: The Development Of Surgical Oncology, Angelos A. Kambouris

Henry Ford Hospital Medical Journal

No abstract provided.

Commencement Program 1982 (Summer Conferring Of Degrees), Loma Linda University

Commencement Programs

CONTENTS

3 | The Academic Procession

4 | Conferring of Degrees

6 | Candidates for Degrees

13 | Awards

Effect Of Levamisole On The Incidence Of Spontaneous Mammary Tumors In C3h Mice, Robert H. Page, Duilio A. Valdivia, Robert W. Talley, Robert A. Huseby

Henry Ford Hospital Medical Journal

Spontaneous mammary carcinoma in C3H mice is preceded by premalignant hyperplastic alveolar nodules. When a primary tumor is evident, examination of the other mammae will reveal a number of microscopic precancerous lesions in various stages of transformation to overt malignant tumors. In an effort to inhibit the development of additional malignant tumors after surgical removal of the first apparent tumor, we treated female C3H/HeJ mice with subcutaneous injections of levamisole (0.6 mg per kg of body weight) on a twice weekly regimen. All further tumors were surgically excised when they became palpable. The surgical excision of bulk tumor burden, immunorestoration …

Acid Phosphatase: Clinical Utility Of The First Tumor Marker, Christopher J. Dipaolo, Jan Rival

Henry Ford Hospital Medical Journal

Acid phosphatase was the first tumor marker to be measured in blood. Although it is used as a marker of prostatic carcinoma, serum levels are also elevated in many diseases of prostate, bone, and hematologic tissue. While serum acid phosphatase concentration is elevated in patients with prostatic carcinoma or infarction, it may also be increased merely with benign hypertrophy and after prostate massage. Recent studies demonstrate that levels are not significantly increased after routine rectal examination. Although of limited use as a screening test, the assay may be useful in staging, prognostication during hormonal therapy, and in making clinical decisions. …

Commencement Program 1982, Loma Linda University

Commencement Programs

CONTENTS

4 | 1982 Events of Commencement

5 | Academic Procession

6 | The Speakers

9 | The Honorees

Order of Programs

• School of Medicine, 12
• Graduate School, 18
• School of Dentistry, 22
• School of Nursing, 28
• School of Education, 31
• College of Arts and Sciences, 36
• School of Allied Health Professions, 42
• School of Health, 47

An Analysis Of A Sample Of Parents And University Freshmen In Regard To Their Attitudes Toward The Needs Of Sex Education In Community Schools, Linda C. Aleksa

Community & Environmental Health Theses & Dissertations

This study attempted to investigate a sample of both parents' and college freshmens' attitudes toward sex education, and the content and timing of sex education in the Tidewater schools. Two Likert-type scales each containing ten statements were administered in order to survey attitudes. A statistically significant difference was found in scores on the attitude toward content and timing of sex education scale between parents and college freshmen. Parents demonstrated a more favorable attitude toward sex education as an integral component of the overall educational curriculum. The majority of parents indicated support for including important aspects such as reproduction and indicated …

Zoonoses In Modern Medical Practice, Tom Madhavan

Henry Ford Hospital Medical Journal

Zoonoses are infections transmitted by animals to man. Of the more than 50 such infections that are clinically significant, several are discussed in the articles by McIntosh and Madhavan and by Meyer and Adar in this issue of the Journal (pp. 7-13). These include brucellosis, leptospirosis, relapsing fever, Colorado tick fever, toxoplasmosis, psittacosis, and echinococcosis. The McIntosh and Madhavan article reviews the experience at Henry Ford Hospital with 60 patients, while the article by Meyer and Adar reports on an unusual case of echinococcosis of the spine and retroperitoneum that occurred at Haim Sheba Medical Center in Israel.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The Multi-Individual Cremation Phenomenon Of The Santa Cruz Drainage, Karl J. Reinhard, T Michael Fink

Karl Reinhard Publications

Multi-individual cremation deposits found in the upper Santa Cruz River drainage were previously interpreted as the result of hypothesized cultural contact in the area. A review of 50 cremation deposits for which detailed analyses are available indicates that mulii-individual cremation deposits are the result of incomplete gleaning practices and have doubtful cultural significance. Hypotheses are generated from the present data which account for the apparent variation in cremation practices within the study area.

Namru-3 Translations Of Parasite Literature From Russian, French, Japanese, Etc. Into English (1931-1982) T1501-T1600, United States Naval Medical Research Unit Number Three, Cairo, Medical Zoology Department

United States Naval Medical Research Unit 3: Publications

T1501. TRANSLATION FROM RUSSIAN. LEONOV, Yu. A. and KHARITONOVA, N. N. (1972). Experimental confirmation of the role of root voles in epizootiology of Omsk hemorrhagic fever. In: Transcontinental associations of migratory birds and their role in distribution of arboviruses, edited by Cherepanov, A. I. Mater. 5. Simp. Izuch. Roli Pereletn. Ptits Rasp. Arbovirus. (Novosibirsk, July 1969), pp. 355-358.

T1503. TRANSLATION FROM RUSSIAN. GASANOV, A. A. (1963). The infection of Rhipicephalus bursa (Can. et Fanz., 1877) with Babesia ovis in the Nakhichevan Region of the ASSR. Izv. Akad. Nauk Azerb. SSR, s. Biol. Med. Nauk, (4):117-123.

T1504. TRANSLATION FROM RUSSIAN. TSAPRUN, …

Clinical Thermoradiotherapy, H. I. Bicher, T. S. Sandhu, F. W. Hetzel

Henry Ford Hospital Medical Journal

No abstract provided.

Local Microwave Hyperthermia In Cancer Therapy. Preliminary Report, Carlos A. Perez, Walter Kopecky, Robert Baglan, D. Venkata Rao, Richard Johnson

Henry Ford Hospital Medical Journal

No abstract provided.

The Role Of Industry In The Development Of Biomedical Technology, Raymond H. Kahn

Henry Ford Hospital Medical Journal

The world is undergoing a biological revolution that has made unparalleled demands on the American health care system. This demand for health care and its escalating costs provide abundant Incentives for reducing the cost through better technology. Recent developments in medical technology include the CAT scanner, nuclear magnetic resonance (NMR), as well as new advances in prosthetic devices. Most biomedical research and development takes place at not-for-profit institutions, such as universities, hospitals, and private foundations, much of it supported by federal funding from such sources as the National Institutes of Health. But, today, the institutions are in danger of major …

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Commencement Program 1981 (Summer Conferring Of Degrees), Loma Linda University

Commencement Programs

CONTENTS

3 | The Academic Procession

4 | Conferring of Degrees

6 | Candidates for Degrees

14 | Awards

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Clinical Thermoradiotherapy, H. I. Bicher, T. S. Sandhu, F. W. Hetzel

Henry Ford Hospital Medical Journal

A clinical trial is currently in progress to determine the efficacy of combined fractions of hyperthermia and radiation. The protocol consists of two parts. First, four fractions of microwave-induced hyperthermia (45.0° ± 0.5°C) are applied for 1 1/2 hours to the volume encompassing the tumor, each separated by 72 hours. After a one-week rest, a second series of four fractions is administered again at 72- hour intervals. Each fraction consists of a 400 rad dose of radiation followed within 20 minutes by hyperthermia (42.5 ± 0.5°C) for 1 1/2 hours. Currently, we have treated 62 patients with 82 fields with …

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Local Hyperthermia And Radiation: A Biologically-Oriented Clinical Scheduling, G. Arcangeli, A. Cividalli

Henry Ford Hospital Medical Journal

In a series of animal tumor studies, heat was directly delivered into the tumor mass with an interstitial applicator. After hyperthermia (44°-45°C for 45 minutes) or radiation alone (3x10 Gy), only a slight delay in tumor growth was observed, while the combined treatment, either simultaneous or sequential (i.e., heat delivered four hours after irradiation), appeared to be the most effective. The cure rate in the two combined treatment groups was 100%, in contrast to the lack of cure in the first two groups. The simultaneous use of heat and x-ray appeared to be slightly more effective than the sequential schedule; …

Hyperthermia, F. K. Storm

Henry Ford Hospital Medical Journal

This report describes the history of hyperthermia and reviews current forms of treatment at both low (42°-43°C) and higher (<45°C) temperatures. Hyperthermia treatment at low temperatures includes fluid immersion and irrigation, regional perfusion with heated fluids, and electromagnetic radiofrequency waves. Low-temperature hyperthermia has also been combined with radiation therapy and with chemotherapy in recent clinical trials. At higher temperatures, we and other investigators have also had promising, preliminary results in treating tumors safely. With the specialized radiofrequency instrumentation we have developed to apply hyperthermia at any depth without preferential surface tissue heating, further clinical investigation of both superficial and deep internal solid tumors is now possible. Recent data suggest that hyperthermia may be an especially effective form of therapy for larger tumors that resist standard forms of treatment. Clinical trials are now underway to determine the most therapeutic dose/time regimen, to determine toxicity and therapeutic enhancement ratios of combined chemotherapy and x-irradiation with hyperthermia, and to evaluate any changes in the host immune system with such therapies.

Hyperthermic Perfusion 16 Years After Its First Clinical Applications, R. Cavaliere, G. Moricca, F. Di Filippo, L. Aloe, G. Monticelli, F. S. Sartori

Henry Ford Hospital Medical Journal

It is known that above-normal temperatures (42°-42.5°C) provoke selective damage to neoplastic cells. We used heated circulating blood as a method for heat transfer on patients with limb tumors. From October 1964 to December 1979, we treated a total of 198 patients with hyperthermic perfusion for melanoma of the limbs (91), osteosarcoma (57), and soft tissue sarcoma (50). For melanoma patients, the five-year survival rate, excluding Stage IV, was 60%. For patients with soft tissue sarcoma, the five-year survival rates were 53% and 56% for hyperthermic perfusion and hyperthermic antiblastic perfusion. respectively. For 29 patients with osteosarcoma, hyperthermic perfusion was …

Local Microwave Hyperthermia In Cancer Therapy: Preliminary Report, Carlos A. Perez, Walter Kopecky, Robert Baglan, D. Venkata Rao, Richard Johnson

Henry Ford Hospital Medical Journal

This report summarizes our preliminary experience at the Mallinckrodt Institute of Radiology treating 26 patients with metastatic tumors with hyperthermia and irradiation. Patients received 400 rad fractions given every 72 hours (twice weekly) for a total of 2400, 2800, 3200, or 4000 rad followed by hyperthermia. In addition, 18 lesions were treated according to a protocol designed by the Radiation Therapy Oncology Group (RTOG) for superficial measurable tumors to receive three doses of 500 rad followed by hyperthermia (six lesions) or irradiation alone (three doses of 600, 700, or 800 rad) every 72 hours. Hyperthermia was administered with 2450 MHz …

Namru-3 Translations Of Parasite Literature From Russian, French, Japanese, Etc. Into English (1921-1981) T1401-T1500, United States Naval Medical Research Unit Number Three, Cairo, Medical Zoology Department

United States Naval Medical Research Unit 3: Publications

T1401. TRANSLATION FROM RUSSIAN. L'VOV, D. K., GROMASHEVSKY, V. L., SIDOROVA, G. A., TSIRKIN, Yu. M. CHERVONSKY, V. L. GOSTINSHCHIKOVA, G. V. and ARISTOVA, V. A. (1971). Isolation of a new arbovirus Baku of Kemerovo group from argasid ticks Ornithodoros coniceps. in Azerbaijan. Vop. Virus., 16(4):434-437.

T1402. TRANSLATION FROM RUSSIAN. ALEKSANDROV, Yu. V., KORYAGIN, V. L. and YOVAL'CHUK, Zh. T. (1970). Observations on ecological biological properties of Hyalomma plumbeum ticks in eastern Crimea. Tezisy Dokl. 2. Akarol. Soveshch., (1):22-24.

T1403. TRANSLATION FROM RUSSIAN. MATEVOSYAN, K. Sh., KARASEVA, P. S. and SEMENOV, B. F. (1974). Study of potential arbovirus foci in …

Commencement Program 1981, Loma Linda University

Commencement Programs

CONTENTS

3 | The President's Greeting

4 | 1981 Events of Commencement

5 | The Academic Procession

6 | The Speakers

9 | The Honorees

11 | Order of Programs

• School of Medicine, 12
• Graduate School, 18
• School of Nursing, 22
• School of Dentistry, 25
• School of Education, 31
• College of Arts and Science, 36
• School of Allied Health Professions, 41
• School of Health, 47

Anywhere But Here: An Introduction To State Control Of Hazardous-Waste Facility Location, A. Dan Tarlock

Articles by Maurer Faculty

No abstract provided.