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Tetanus Toxoid, Reduced Diphtheria Toxoid And Acellular Pertussis Vaccination And Influenza Vaccination Of Pregnant And Postpartum Women, Colleen M. Mccormick

Master of Public Health Program Student Publications

Introduction: Infants ≤2 months are at greatest risk for morbidity/mortality from pertussis. Tdap vaccines given in late pregnancy or postpartum can protect infants from pertussis. Pregnancy increases risks for maternal and perinatal complications. Influenza vaccine (FLUV) given in pregnancy can protect women and newborns.

Objectives: To determine Tdap and FLUV rates in pregnant and postpartum patients and identify factors associated with vaccination.

Methods: Miami Valley Hospital delivery records from 01/2009-12/2011 were retrospectively reviewed. Data reviewed included age, insurance, race/ethnicity, and county of residence. Descriptive statistics analyzed prevalence of immunization, timing, and demographics. Chi-square and odds ratios detected differences between characteristics. …

From Service Provision To Function Based Performance - Perspectives On Public Health Systems From The Usa And Israel, F. Douglas Scutchfield, Ehud Miron, Richard Ingram

Preventive Medicine and Environmental Health Faculty Publications

If public health agencies are to fulfill their overall mission, they need to have defined measurable targets and should structure services to reach these targets, rather than offer a combination of ill-targeted programs. In order to do this, it is essential that there be a clear definition of what public health should do- a definition that does not ebb and flow based upon the prevailing political winds, but rather is based upon professional standards and measurements.

The establishment of the Essential Public Health Services framework in the U.S.A. was a major move in that direction, and the model, or revisions …

Prevention Education Effects On Fundamental Memory Processes, Susan L. Ames, Marvin D. Krank, Jerry L. Grenard, Steve Sussman, Alan W. Stacy

CGU Faculty Publications and Research

This study evaluated effects of a key session from a nationally recognized drug abuse prevention program on basic memory processes in 211 high-risk youth in Southern California. In a randomized, between-subject design, the authors manipulated assignment to a Myth and Denial program session and the time of assessment (immediate vs. 1-week delay). The authors examined program decay effects on memory accessibility and judgment errors. Those participants exposed to the program session generated more myths and facts from the program than those in the control group, suggesting that even a single program session influenced students’ memory for program information and this …

Pursuing High Performance In Rural Health Care, A. Clinton Mackinney Md, Ms, Keith J. Mueller Phd, Andrew F. Coburn Phd, Jennifer P. Lundblad Phd, Mba, Timothy D. Mcbride Phd, Sidney D. Watson Jd

Health System Reform

Rural Futures Lab Foundation Papers are intended to present current thinking on the economic drivers and opportunities that will shape the future of rural America. They provide the foundation upon which it will be possible to answer the question that drives the Lab’s work—What has to happen today in order to achieve positive rural outcomes tomorrow?

Community Member Perspectives From Transgender Women And Men Who Have Sex With Men On Pre-Exposure Prophylaxis As An Hiv Prevention Strategy: Implications For Implementation, Gabriel R. Galindo, Ja'nina Walker Ph.D., Patrick Hazelton, Tim Lane, Wayne T. Steward, Stephen F. Morin, Emily A. Arnold

Psychology

Background: An international randomized clinical trial (RCT) on pre-exposure prophylaxis (PrEP) as an human immunodeficiency virus (HIV)-prevention intervention found that taken on a daily basis, PrEP was safe and effective among men who have sex with men (MSM) and male-to-female transgender women. Within the context of the HIV epidemic in the United States (US), MSM and transgender women are the most appropriate groups to target for PrEP implementation at the population level; however, their perspectives on evidenced-based biomedical research and the results of this large trial remain virtually unknown. In this study, we examined the acceptability of individual daily use …

Antibiotics For Leptospirosis, David Brett-Major, Rodney Coldren

Journal Articles: Epidemiology

BACKGROUND: Leptospirosis has a wide-ranging clinical and public health impact. Leptospira are globally distributed. Case attack rates are as high as 1:4 to 2:5 persons in exposed populations. In some settings mortality has exceeded 10% of infected people. The benefit of antibiotic therapy in the disease has been unclear.

OBJECTIVES: We sought to characterise the risks and benefits associated with use of antibiotic therapy in the management of leptospirosis.

SEARCH METHODS: We searched the The Cochrane Hepato-Biliary Group Controlled Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, MEDLINE, EMBASE, and Science Citation Index Expanded …

Chhs January 2012 E-Newsletter, Dr. John Bonaguro, Dean, Vashon S. Wells, Editor, Wku College Of Health & Human Services

College of Health & Human Services Publications

No abstract provided.

Best Practice For Casualty Simulation - Role-Playing Actor, High Fidelity Mannequin Simulation, Or Virtual Reality?, Robert Sarlay

Master of Public Health Program Student Publications

Objective: The purpose of this systemic review of the literature is to determine the best practice with regards to simulating casualties during a disaster response exercise.

Methods: MEDLINE was searched from 1950 till present for the key terms of disaster, simulation, and emergency preparedness. Articles were included which met the following criteria: English language, human subjects, original research using any research design (with or without intervention), and primary focus of disaster preparedness using simulation, virtual reality, or role playing actors.

Results: Of the 386 articles reviewed only 18 met inclusion criteria. The literature is primarily descriptive in nature with regards …

A Guide To Acquiring Healthy Nutrition And Fitness Habits For College Students: Preventing Diabetes, Hypertension, Coronary Heart Disease, And Stroke, Darin P. Dillinger

Master of Humanities Capstone Projects

For the past three decades, obesity has been cited as a growing epidemic in the United States, according to the New England Journal of Medicine (NEJM). Obesity is a major contributing problem to a number of medical conditions. Studies in the NEJM have “correlated obesity with myriad cancers, coronary heart disease, hypertension, diabetes, and stroke,” and other health-related problems (Fumento). Healthcare experts, doctors, and practitioners estimate it will cost billions of dollars a year to bring this problem under control and it is a major contributing factor in the rising cost of healthcare (Oliver 1). Luppold, Violette, and other practitioners …

State Policies For Health Education In Public Schools, Lynda K. Vu

Master of Public Health Program Student Publications

Background: Federal and state governmental activities have significantly influenced schools’ health education practices over the past 50 years. Evaluation of these initiatives in the scientific literature has enhanced development of health education and influenced the creation of the National Health Education Standards (NHES). The Centers for Disease Control and Prevention (CDC) conducts periodic surveys to evaluate the impact of state and local policies on school health education programs and practices.

Objectives: This research project reviews and analyzes state health education policies for the 50 states plus the District of Columbia with regard to the recommendations of the NHES. It also …

Factors That Influence Food Access In The United States: A Snapshot Of Food Access In Ohio And Kentucky, Maimouna Falls

Master of Public Health Program Student Publications

Background: The United States is one the richest countries in the world with a Gross Domestic Product (GDP) per capita of $48,442, yet many communities lack access to affordable nutritious food. Access to food impacts health outcomes such as obesity and diabetes. The purpose of this study was to determine the association between food access and rates of obesity and diabetes in the states of Ohio and Kentucky.

Methods: County level food access data from 120 counties in Kentucky and 88 counties in Ohio were obtained from the USDA website. The dataset included demographic variables and poverty rates. Food access …

Improving Childhood Nutrition In Rural Dominican Republic, Christine L. North

Master of Public Health Program Student Publications

This nutrition education intervention seeks to decrease malnutrition and increase overall health status of rural Dominican Republic children in the village of El Cercado, Dominican Republic. Working with the Child Nutrition Program run by Solid Rock International, this educational intervention will target caregivers of children enrolled in the nutrition program. Using a multi-level strategy, this intervention focuses on hygiene practices and safe food preparation, formalized nutrition education, food access and introduction of new foods. Caregivers will take part in five interactive lesson sessions where they will engage in hands-on learning and skill development associated with the target areas. Additionally, clinic …

Factors That Influence Immunization Status Among A Sample Of University Students, Abigail Marie Miller

Theses Digitization Project

The purpose of this study was to gather demographic information about the sample population as well as information on their attitudes, knowledge, and behaviors in relation to immunizations, vaccine-preventable diseases, and the immunization policies for entrance into California State University, San Bernardino (CSUSB).

Urban Governance Of Disease, Rebecca Katz, Sangeeta Mookherji, Morgan Kaminski, Vibhuti Haté, Julie E. Fischer

Global Health Faculty Publications

Rapid population growth, urbanization, and the growing challenges faced by the urban poor require redefining the paradigm for public health interventions in the 21st century, creating new approaches that take urban determinants of health into consideration. The widening disparity between the urban poor and the urban rich further exacerbates health inequities. Existing tools for global governance of urban health risks fall short, particularly in the lack of formal mechanisms to strengthen collaboration and communication among national and municipal agencies and between their local and international non-governmental partners. There is also a clear disconnect between governance strategies crafted at the international …

Smoking Susceptibility And Its Predictors Among Adolescents In China: Evidence From Ningbo City, Cheng Huang, Jeffrey Koplan, Jing Liu, Changwei Li, Jessica Silvaggio, Amanda K. Macgurn, Tao Zhang, Michael P. Erikson, Pam Redmon

Global Health Faculty Publications

Susceptibility to smoking is a risk factor of actual adolescent smoking behaviors. This study aimed to estimate the rate of smoking susceptibility and its predictors in China with a sample of 4,695 junior high school students in Ningbo, China. Core questions from the Global Youth Tobacco Survey (GYTS) were adapted to the China context and administered to these students. The rate of smoking susceptibility, measured by “Do you foresee yourself taking up smoking in the next 12 months”, is 6.1%. Results from logistic regression suggested that among boys, adolescents’ health knowledge that smoking can cause lung cancer (OR=2.73), the belief …

Health Effects Associated With Foreclosure: A Secondary Analysis Of Hospital Discharge Data, Nancy Menzel, Sheniz Moonie, Melva V. Thompson-Robinson

Nursing Faculty Research

Objectives. The purpose of this study was to assess the health effects of high home foreclosure rates in an area of the United States of America and the utility of hospital discharge data for this purpose. Methods. We analyzed hospital discharge data from three postal zip codes using the principal diagnosis for 25 Diagnostic Related Groups associated with stress. Descriptive statistics were used to characterize hospital discharge rates for each condition by year and zip code. To test for differences across time, the Cochran-Armitage trend test was performed. Results. Most conditions did not demonstrate a statistical change between …

Erlin2 Promotes Breast Cancer Cell Survival By Modulating Endoplasmic Reticulum Stress Pathways, Guohui Wang, Gang Liu, Xiaogang Wang, Seema Sethi, Rouba Ali-Fehmi, Judith Abrams, Ze Zheng, Kezhong Zhang, Stephen Ethier, Zeng-Quan Yang

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Amplification of the 8p11-12 region has been found in approximately 15% of human breast cancer and is associated with poor prognosis. Previous genomic analysis has led us to identify the endoplasmic reticulum (ER) lipid raft-associated 2 (ERLIN2) gene as one of the candidate oncogenes within the 8p11-12 amplicon in human breast cancer, particularly in the luminal subtype. ERLIN2, an ER membrane protein, has recently been identified as a novel mediator of ER-associated degradation. Yet, the biological roles of ERLIN2 and molecular mechanisms by which ERLIN2 coordinates ER pathways in breast carcinogenesis remain unclear.

Methods

We established the MCF10A-ERLIN2 …

United States Registered Nurse Workforce Report Card And Shortage Forecast, Stephen P. Juraschek, Xiaoming Zhang, Vinoth K. Ranganathan, Vernon Lin

United States Public Health Resources

Registered nurses (RNs) play a critical role in health care delivery. With an aging US population, health care demand

is growing at an unprecedented pace. Using projected changes in population size and age, the authors developed

demand and supply models to forecast the RN job shortage in each of the 50 states. Letter grades were assigned

based on projected RN job shortage ratios. The number of states receiving a grade of “D” or “F” for their RN

shortage ratio will increase from 5 in 2009 to 30 by 2030, for a total national deficit of 918 232 (725 619 - …

Clinical Research And Development Of Tuberculosis Diagnostics: Moving From Silos To Synergy, Payam Nahid, Peter S. Kim, Carlton A. Evans, David Alland, Michael Barer, Jane Diefenbach, Jerrold Ellner, Richard Hafner, Carol Dukes Hamilton, Michael F. Iademarco, Gregory Ireton, Michael E. Kimerling, Christian Lienhardt, William R. Mackenzie, Megan Murray, Mark D. Perkins, Jamie E. Posey, Teri Roberts, Christine Sizemore, Wendy S. Stevens, Laura Via, Sharon D. Williams, Wing Yew, Susan Swindells

United States Public Health Resources

The development, evaluation, and implementation of new and improved diagnostics have been identified as critical needs by human immunodeficiency virus (HIV) and tuberculosis researchers and clinicians alike. These needs exist in international and domestic settings and in adult and pediatric populations. Experts in tuberculosis and HIV care, researchers, healthcare providers, public health experts, and industry representatives, as well as representatives of pertinent US federal agencies (Centers for Disease Control and Prevention, Food and Drug Administration, National Institutes of Health, United States Agency for International Development) assembled at a workshop proposed by the Diagnostics Working Group of the Federal Tuberculosis Taskforce …

Salmonella Enterica Serotype Enteritidis: Increasing Incidence Of Domestically Acquired Infections, Shua J. Chai, Patricia L. White, Sarah L. Lathrop, Suzanne M. Solghan, Carlota Medus, Beth Mcglinchey, Melissa Tobin-D'Angelo, Ruthanne Marcus, Barbara Mahon

United States Public Health Resources

Background. Salmonella enterica causes an estimated 1 million cases of domestically acquired foodborne illness in humans annually in the United States; Enteritidis (SE) is the most common serotype. Public health authorities, regulatory agencies, food producers, and food processors need accurate information about rates and changes in SE infection to implement and evaluate evidence-based control policies and practices.

Methods. We analyzed the incidence of human SE infection during 1996–2009 in the Foodborne Diseases Active Surveillance Network (FoodNet), an active, population-based surveillance system for laboratory-confirmed infections. We compared FoodNet incidence with passively collected data from complementary surveillance systems and with …

Cytokine Responses In Whole Blood Assay In Veterans With Agriculture Work Exposures, J. D. J. Romberger, J. L. Meza, E.C. Chickris, A. J. Heires, R. M. Zotti-Pierce, T. D. Levan

United States Public Health Resources

RATIONALE: Agriculture exposures are associated with increased risk of chronic obstructive pulmonary disease (COPD). Endotoxin exposure in agricultural environments is associated with lung disease. Our objective was to evaluate responsiveness to endotoxin stimulation in an in vitro whole blood assay and its association with COPD in an agriculturally exposed cohort.

METHODS: Veterans with ≥ two years agricultural work exposure participated in this case-control study. Cases are veterans with COPD defined as FEV1/FVC ratio < 70% on spirometry post-bronchodilator. Controls did not have COPD as assessed by spirometry nor other significant lung conditions. Whole blood assay (WBA) was done with 2 ml heparinized blood mixed with 2 ml of media and stimulated with increasing doses of LPS (0 – 1 ng/ml). Samples were incubated at 37°C for 24 hours, centrifuged, supernatants harvested and frozen until assayed for cytokines by ELISA. Cytokine values were log transformed. Repeated measures ANOVA was used to examine the association between LPS dose and group (case or control) and the interaction of dose with group. All p values were adjusted for age.

RESULTS: There were 272 participants, 110 cases with COPD and 158 controls. Baseline demographics (gender, age, race) were similar between cases and controls. LPS-stimulated …

Scavenger Receptor A Activation Enhances Peptidoglycan-Stimulated Interleukin-8 Release In Bronchial Epithelium, J. P. Berger, K. L. Bailey, J. M. Devasure, D. J. Romberger, T. A. Wyatt

United States Public Health Resources

INTRODUCTION: The immune response to certain pathogens or cellular stressors is initiated and regulated by pattern recognition receptors of the innate immune system. Pattern recognition receptors are effective by utilizing either endocytic (Scavenger Receptors) or signaling receptors (Toll-like Receptors). It has been previously demonstrated that mouse dendritic cells deficient in scavenger receptor A (SRA) negatively regulated the immune response produced by Toll-like receptors when exposed to modified lipid proteins. Previously, we have shown that peptidoglycan contained in organic dust from swine barns stimulates pro-inflammatory cytokine release in bronchial epithelium. We hypothesized bronchial epithelial SRA would also have a regulatory …

Assessing And Improving Self-Reporting Of Male Circumcision In Zambia And Swaziland, Paul C. Hewett, Nicole Haberland, Barbara Mensch, Louis Apicella

HIV and AIDS

The Male Circumcision (MC) Partnership was established with the support of the Gates Foundation and PEPFAR to scale up MC services in Zambia, in collaboration with the Zambian government. The MC Partnership is a five-year project led by Population Services International (Society for Family Health, Zambia), in partnership with Jhpiego, Marie Stopes International (MSI), and the Population Council. The ultimate objective of this study is to provide researchers and program managers with evidence-based recommendations for the collection of self-reported data on MC status through an assessment of different methods to describe and explain MC. Specifically, the study assessed tools for …

An Assessment Of Individual And Institutional Research Utilization By Policy-Makers And Programme Managers At State And National Levels In Nigeria, National Agency For The Control Of Aids

HIV and AIDS

This report undertakes a systematic assessment of the need for evidence by decision-makers working on HIV and AIDS funding and policymaking, and implementing organizations at the national and subnational levels in Nigeria. The assessment identifies barriers and constraints to data use, identifies best practices, and offers recommendations for the design and prioritization of strategic approaches to address barriers and constraints in data use and production. Tools to monitor the adoption of evidence in policy and practice are also offered. The need for evidence-based practice in the national response to HIV and AIDS has been widely acknowledged and incorporated into policy …

Perceptions Of Risk Associated With Unintended Pregnancy And Sexually Transmitted Infections Among University Women Attending Minnesota State University, Mankato, Jessica Maria Seide

All Graduate Theses, Dissertations, and Other Capstone Projects

Unintended pregnancies and sexually transmitted infections are preventable, yet there is still a high occurrence of both among university women. This study evaluated perceptions of risk associated with unintended pregnancies and sexually transmitted infections among selected university women aged 18-25. This study identified whether women's perceptions of risk affected their decision to take certain precautions to prevent pregnancies and sexually transmitted infections. This study also examined whether there was a relationship between perceptions of risk associated with unintended pregnancies and perceptions of risk associated with sexually transmitted infections and some of the variables that are associated with that relationship. This …

The Role Of Local Food In Increasing Access To Healthy Food In Indianapolis, Indiana, Anna Hostetter

Capstone Collection

In the United States today, incidents of obesity are on the rise, currently more than one-third, or 35.7% of U.S. adults are considered obese, up from 30.5% in 2000. These startling numbers are causing news institutions and politicians to refer to it as the “obesity epidemic”.

Obesity is linked to multiple health problems including Type 2 diabetes, coronary heart disease, hypertension, and breast cancer (Aronne, L.J., 2002). There are numerous causes of obesity, including genetics, yet high rates of obesity have also been positively linked with a diet high in processed foods and low in fruits and vegetables (Drewnowski, A. …

Governance In Large Nonprofit Health Systems: Current Profile And Emerging Patterns, Lawrence Prybil, Samuel Levey, Rex Killian, David Fardo, Richard Chait, David R. Bardach, William Roach

Health Management and Policy Faculty Book Gallery

From the foreword:

Nonprofit healthcare organizations are not exempt from good governance. In fact, more today than ever, the hospitals and health care systems of this country must have the discipline and commitment to organize their governance structures and practices to provide forward-thinking leadership and stand up to scrutiny from any type of evaluation and review. As we move from “sick care” organizations to “health care” organizations with accountability for the health of the population of our communities from birth to end-of-life, the role of governance becomes even more critical.

Fourteen of the largest and most notable health care systems …

Marps Sensitization: A Diversity Training Guide For Health Care Providers In Nigeria, Enhancing Nigeria's Hiv/Aids Response (Enr) Programme

HIV and AIDS

Men who have sex with men (MSM) present specific diagnostic and management challenges to counselors and health-care providers. High prevalence of HIV infection has been reported among MSM in Nigeria, driven partly by stigma, discrimination, lack of appropriate prevention strategies, limited research evidence, little recognition by policymakers, and inadequate knowledge and skills in dealing with MSM clients. In Nigeria, where homosexuality is illegal, the risk embodied in same-sex activities is high and makes hiding MSM activities almost a norm. Currently, health-care provider training materials that address most at-risk populations’ (MARPs) specific health needs are nonexistent in Nigeria. Knowledge of these …

Effective Pedometer Programs: Determining The Motivational Factors Primarily Responsible For The Physical Activity Increases Being Made By Participants, Britne Engelking

All Graduate Theses, Dissertations, and Other Capstone Projects

Statement of the Problem: Adults continue to get inadequate amounts of physical activity (Flegal et al., 2010; WCRF/AICR, 2009). Pedometer programs being implemented have effectively motivated the participants to increase their physical activity outputs; however, researchers have been unable to determine the features responsible for the physical activity increases. Procedures: Participants were given pedometers to measure their physical activity outputs. The participants collected baseline data for one week. The experimental group was administered three competitive incentive interventions. Their data was compared to their baseline step data and step data collected from a control group. The data analysis was done using …

Adapting The Pprnet Trip Qi Model To Increase Colorectal Cancer Screening In Primary Care: A Feasibility Study, Katherine Attassi

MUSC Theses and Dissertations

The value of using colorectal cancer screening (CRCS) as a preventative tool in the development of colorectal cancer (CRC) is well established; however, mobilizing patients to participate in one of the CRCS methods remains an issue. Research to engage patients more actively in CRCS has shown that health care providers have the most influence on patient participation. This dissertation first examines the various provider-directed interventions proven to increase CRCS in the primary care setting. Next, the detailed theoretical and methodological processes are examined based on the previous research from the first article. The PPRNet TRIP QI Model was chosen based …