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Establishing The Discriminative Stimulus Properties Of The Atypical Antipsychotic Amisulpride In C57bl/6 Mice, Timothy J. Donahue

Theses and Dissertations

Abstract ESTABLISHING THE DISCRIMINATIVE STIMULUS PROPERTIES OF THE ATYPICAL ANTIPSYCHOTIC AMISULPRIDE IN C57BL/6 MICE Antipsychotic medications are used to treat schizophrenia. The present study used the drug discrimination paradigm to measure the subjective effects of the atypical antipsychotic amisulpride and to examine the underlying neuropharmacological mechanisms responsible for the discriminative stimulus property of the drug. Male C57BL/6 mice were trained to discriminate 10 mg/kg (-)S amisulpride from vehicle in a two-lever drug discrimination task. A dose effect curve for (-)S amisulpride yielded an ED50 = 1.77 mg/kg 95% CI [1.28, 2.45 mg/kg]. Substitution testing was conducted for the isomer (+)R …

A Longitudinal Study Of The Effect Of At Birth Adoptions On Anxiety, Stress Hormones And Adolescent Alcohol Intake: A Nonhuman Primate Model, Whitney Faith Maxwell

Theses and Dissertations

Adopted individuals have an increased risk for a variety of psychopathological disorders. Studies of the effects adoption in humans are difficult to perform because of the difficulty separating genetic risk and treatment effects. This is a developmental study investigating the effects of at birth adoption using a nonhuman primate model. Three experimental paradigms were used to assess maternal treatment, stress-related behavior, and physiology late in infancy and again later in life. Rhesus monkeys were reared for their first six months of life by either their biological mother or an unrelated, lactating adult female. Adoptions occurred immediately following birth. At six …

A Qualitative Analysis Of High School Students' Experiences In The Latinos In Action Program, Johann Paul Simonds

Theses and Dissertations

This research was a qualitative program evaluation of students' perceptions of Latinos in Action (LIA), a peer-mentoring program that seeks to improve high school Latino graduation rates and college admittance. The study was conducted with college students who participated in the program in high school. LIA graduates were interviewed to determine what major factors influenced and supported them in their academic decisions. Additional data included an interview with the program director, results from the High School Survey of Student Engagement (HSSSE), and a video of one of the interviewees. The researcher explored students' experiences in the LIA program with the …

Behavioral Phenotyping Of The Discriminative Stimulus Properties Of The Atypical Antipsychotic Drug Clozapine In 129s2/Hsv Mice, Kevin Webster

Theses and Dissertations

The 129S2 inbred mouse strain is often used as a background strain in the production of genetically altered mice (i.e. knockout and transgenic mice). It is important to establish the behavioral phenotype of wild-type mice before making comparisons to genetically altered mice. Also, those comparisons can assist in the evaluation and interpretation of the in vivo effects of drugs. The drug discrimination assay measures the subjective effects of drugs and provides a measure of underlying neuropharmacological mechanisms responsible for the discriminative stimulus properties of drugs. The present study established the atypical antipsychotic drug clozapine as a discriminative stimulus in male …

The Rewarding Effects Of Nicotine Are Enhanced In Diabetic Rats Given Extended Access To Intravenous Self-Administration Procedures, Julio C. Chaparro, Jesse A. Jurado, Nicole M. Kimura, Laura E. O'Dell

COURI Symposium Abstracts, Summer 2012

Diabetic patients who use tobacco display higher mortality rates as compared to healthy individuals who also use tobacco. Despite the magnitude of the problem, it is unclear whether diabetic subjects display enhanced rewarding effects that may lead to greater vulnerability to abuse tobacco as compared to healthy controls. To address this question, a rat model was used whereby diabetes is induced via administration of streptozotocin (STZ), a drug that is toxic to insulin-producing beta cells in the pancreas. Following diabetes induction, control or diabetic rats were given access to intravenous self-administration (IVSA) of nicotine in extended 23-hour or limited 1-hour …

Enhanced Rewarding Effects Of Nicotine Are Observed In Diabetic Rats As Assessed By Conditioned Place Preference Procedures, Nicole M. Kimura, Ivan D. Torres, Julio Chaparro, Laura E. O'Dell

COURI Symposium Abstracts, Summer 2012

Previous work in our laboratory has shown that diabetic rats self-administer more nicotine compared to healthy controls, possibly because diabetic animals find nicotine more rewarding. This study further compared the rewarding effects of nicotine in diabetic and control rats using conditioned place preference (CPP) procedures. CPP examines whether animals prefer a side of the chamber where they previously received nicotine as compared to a neutral side. Diabetes was induced using streptozotocin (STZ), a drug that is toxic to insulin producing cells in the pancreas. STZ- or vehicle-treated rats (n=11-16) were tested for their initial preference for the 2 compartments of …

Building Trust And Collaboration With Rural Minorities: Experiences With Minority Farmers In The Mississippi Delta, Ari Mwachofi

Journal of Health Disparities Research and Practice

The paper focuses on the question “What research approach is effective in building trust with minority farmers?” The question is answered through a documentation of researchers’ experiences building trust and collaboration with minority farmers in the lower Mississippi Delta. The researchers applied two research paradigms -logical positivism and paradigm of praxis. The logical positivism research approach was met with mistrust and open animosity and had to be abandoned for one based on the paradigm of praxis. Through this approach, and cognizant of the historical-social-political context, the researchers included insiders from the focus population as collaborators and researchers and succeeded in …

The Optimal Calibration Hypothesis: How Life History Modulates The Brain's Social Pain Network, David S. Chester, Richard S. Pond Jr., Stephanie B. Richman, C. Nathan Dewall

Psychology Faculty Publications

A growing body of work demonstrates that the brain responds similarly to physical and social injury. Both experiences are associated with activity in the dorsal anterior cingulate cortex (dACC) and anterior insula. This dual functionality of the dACC and anterior insula underscores the evolutionary importance of maintaining interpersonal bonds. Despite the weight that evolution has placed on social injury, the pain response to social rejection varies substantially across individuals. For example, work from our lab demonstrated that the brain's social pain response is moderated by attachment style: anxious-attachment was associated with greater intensity and avoidant-attachment was associated with less intensity …

It Pays To Cheat: Tactical Deception In A Cephalopod Social Signalling System, Culum Brown, Martin P. Garwood, Jane E. Williamson

Communication Skills Collection

Signals in intraspecific communication should be inherently honest; otherwise the system is prone to collapse. Theory predicts, however, that honest signalling systems are susceptible to invasion by cheats, the extent of which is largely mediated by fear of reprisal. Cuttlefish facultatively change their shape and colour, an ability that evolved to avoid predators and capture prey. Here, we show that this ability is tactically employed by male mourning cuttlefish (Sepia plangon) to mislead conspecifics during courtship in a specific social context amenable to cheating 39 per cent of the time, while it was never employed in other social contexts. Males …

Malingering Detection Measure Utility And Concordance In A University Accommodation-Seeking Student Population, Nichole M. Loser

Theses and Dissertations

According to the Americans with Disabilities Act, universities and colleges are required to provide accommodative services for students with disabilities. Many studies have examined the role of malingering mental health symptoms in order to obtain psychotropic medications, but very little research has been done on the role of accommodations as secondary gain in students who may malinger learning disabilities. This study sought to examine both the usefulness of implementing specific malingering detection measures in psychological evaluations with university students and the agreement of those measures within the population. Archival data was gathered from a university accommodation clinic that provided free …

The Evolution Of Conservative Attitudes As A Complement To Cognitive Threat Detection Mechanisms, Russ Clay

Theses and Dissertations

Conservatism reflects a general attitude structure characterized by a preference for traditional social practices and an aversion to uncertainty and threat. Though the social environment undoubtedly plays a role in shaping conservative attitudes, recent studies suggest that trait-level characteristics may contribute to their development as well. The present research investigated trait-level cognitive threat detection ability as a factor which may influence the development and maintenance of conservative social attitudes. A computer simulation indicated that socially conservative attitudes may function as a strategy for increasing the survival rate of an individual with poor threat detection ability living in a relatively dangerous …

The Influence Of Carl Jung’S Archetype Of The Shadow On Early 20th Century Literature, Dana Brook Thurmond

Master of Liberal Studies Theses

This thesis seeks to establish a direct relationship between the archetypes of Carl Jung, primarily the Shadow, and early 20th century literature. The Shadow is best described as our darker selves, the primitive unconsciousness that subtly invades our waking moments. Modern society has sought to suppress this Shadow, which has led to repression and potential psychoses. Many authors of the late Victorian and early modern period address the problems with societal expectations in their works. This thesis will explore the writing of Henry James, Bram Stoker, Robert Louis Stevenson, and T. S. Eliot to see how they deal with Jung's …

Does Terrain Slope Really Dominate Goal Searching?, Daniele Nardi

Faculty Research and Creative Activity

If you can locate a target by using one reliable source of information, why would you use an unreliable one? A similar question has been faced in a recent study on homing pigeons, in which, despite the presence of better predictors of the goal location, the slope of the floor in an arena dominated the searching process. This piece of evidence seems to contradict straightforward accounts of associative learning, according to which behavior should be controlled by the stimulus that best predicts the reward, and has fueled interest toward one question that, to date, has received scarce attention in the …

Spirituality And Hallucinogen Use: Results From A Pilot Study Among College Students, Adam Stasko, Satya P. Rao, Amy Pilley

International Journal of Transpersonal Studies

Anthropologists have studied the use of hallucinogens as a spiritual tool by indigenous

populations since the turn of the 20th century. However, literature is sparse in describing

use by non-indigenous populations. Using a study population of students from a university

in the Southwest United States, the current study investigated the spiritual development and

meaning that college students place on their use of hallucinogenic substances. The spiritual

framework developed by Love and Talbot (1999) and a transpersonal anthropological

approach were used to guide the study. Semi-structured interviews were conducted with

each participant. Results indicated that participants used hallucinogens for both spiritual …

Shamans As Healers, Counselors, And Psychotherapists, Stanley Krippner

International Journal of Transpersonal Studies

Shamanic models of healing, counseling, and psychotherapy differ from Western models in that

they emphasize closeness to the natural world as well as to one’s body and life’s spiritual dimensions.

Shamanic practices reflect the ideals of harmony and knowledge. In shamanism, there is no division

between “mind” and “body,” hence what Westerners refer to as “mental illness” is seen as part of

the total client being treated by a shaman, a perspective that often includes the client’s family,

community, and the world of “spirits.”

Experiences Of “Soul Journeys” In The World’S Religions: The Journeys Of Mohammed, Saints Paul And John, Jewish Chariot Mysticism, Taoism’S Highest Clarity School, And Shamanism., Roger Walsh

International Journal of Transpersonal Studies

“Soul journeys” are a central practice of shamanism. However, they have also been important

in many other religious traditions and have exerted a major impact on religions, cultures, and

history. This article surveys some important journeys in the world’s religions such as those of

Mohammed, the Christian saints Paul and John, Jewish Chariot Mysticism, Taoism’s Highest

Clarity tradition, and shamanism. The article explores the experiences of these journeys, techniques

for inducing them, culturally specific features, and the range of metaphysical interpretations of

them. It also examines some of the surprising ways in which journeys are currently impacting

Western culture, ranging …

Transpersonal Effects Of Exposure To Shamanic Use Of Khoomei (Tuvan Throat Singing): Preliminary Evaluations From Training Seminars, Vladislav Matrenitsky, Harris L. Friedman

International Journal of Transpersonal Studies

Khoomei is a Tuvan Siberian shamanic practice involving overtone throat singing. One hundred eighty-one Western participants completed questionnaires after attending Khoomei seminars, asking about the following: motivation of people to learn shamanic throat singing; self-perception at the levels of body, energy, and mind before-and-after the seminar; feelings and sensations from practicing throat singing; transpersonal experience during throat singing; experience of inner vibrations from listening to the singing; and general state and feelings after seminar. In general, most participants reported many benefits from attending the seminars, although a few reported mild negative effects (e.g., dizziness and sadness). Of particular interest are …

Postmodern Trickster Strands In Shamanic Worlds, Jürgen W. Kremer

International Journal of Transpersonal Studies

This essay explores socio-philosophical meanings of shamanic cultures and practices and

their affirmation and revival. What is their potential significance for humanity’s future? I

argue that shamanism engages humans in practices that put us potentially at the center of

our creativity and creative visioning. The trickster figure, a pervasive indigenous presence,

so often seems pivotal in this process and this pervasively male figure plays an important

part in this regenerative interpretation of postmodernism; in fact, postmodernism can be

understood as trickster. Just like the trickster, the nature of postmodernism is ambiguous.

I explore this ambiguity and suggest that shamanic practices …

My Path In Shamanism, Michael Harner

International Journal of Transpersonal Studies

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Shamanism, Imagery Cultivation, And Psi-Signal Detection: A Theoretical Model, Experimental Protocol, And Preliminary Data, Adam J. Rock, Lance Storm

International Journal of Transpersonal Studies

NA

Effects Of Gender Composition Of Target And Sender Dyads On The Tendency To Infer Lies, Byron J. Simoneaux

Doctoral Dissertations

Lying is so common in human behavior that some have labeled it a social skill. Despite the ubiquity of lies, humans have consistently been found to be poor lie detectors. Attempts have been made to improve the accuracy of human lie detection. Unfortunately, the most successful training only improves accuracy slightly above the level of chance. Because of its importance to society, considerable effort has been aimed at developing methods to help determine when people are lying. Researching how and why humans infer that another person is lying has the potential to advance the understanding of lie detection. Researchers have …

Comparing Overexcitability Levels Between Stem Talented Students And Generally Gifted Students Using The Oeqii, Taylor Imburgia '13, Deborah Mcgrath, Christopher G. Kolar

Student Publications & Research

Gifted individuals have been shown to have higher developmental potential, making them more likely to exhibit overexcitabilities (OEs) classified as psychomotor, sensual, intellectual, imaginational, or emotional. The OE levels between IMSA males and females and between IMSA students interested in STEM and Ohio generally gifted students were examined using the Overexcitabilty Questionnaire-two. Data from 70 IMSA sophomores were analyzed using descriptive statistics, ANOVA, and Bonferroni Correction method. Results showed that IMSA females had significantly higher sensual and emotional levels than males. Both IMSA males and females exhibited significantly lower imaginational OE levels than the Ohio students. This study will hopefully …

Proposed Dsm-5 Personality Traits And Substance Use: A Multi-Faceted Study, W. Reese Mayer

Doctoral Dissertations

In this study, the Brief Assessment of Traits – 37 (BAT37) was developed to measure the presence of the personality traits initially proposed for inclusion in the personality disorders section of the DSM-5. The structure of the measure was supported by the results of a pilot study and its construct validity was supported by correlations with theoretically-related scales from the PAI, DAPP-BQ, and HEXACO-PI-R. The BAT37 was administered to a sample of undergraduate college students and clients at a residential substance use disorder (SUD) treatment facility.

Several of this study's findings are relevant to the proposed changes to the personality …

Shamanism In Cross-Cultural Perspective, Michael Winkelman

International Journal of Transpersonal Studies

This article reviews the origins of the concept of the shaman and the principal sources of

controversy regarding the existence and nature of shamanism. Confusion regarding the

nature of shamanism is clarified with a review of research providing empirical support for a

cross-cultural concept of shamans that distinguishes them from related shamanistic healers.

The common shamanistic universals involving altered states of consciousness are examined

from psychobiological perspectives to illustrate shamanism’s relationships to human nature.

Common biological aspects of altered states of consciousness help explain the origins of

shamanism while social influences on this aspect of human nature help to explain …

Color In Context: Psychological Context Moderates The Influence Of Red On Approach- And Avoidance-Motivated Behavior, Brian P. Meier, Paul R. D'Agostino, Andrew J. Elliott, Markus A. Meier, Benjamin M. Wilkowski

Psychology Faculty Publications

A basic premise of the recently proffered color-in-context model is that the influence of color on psychological functioning varies as a function of the psychological context in which color is perceived. Some research has examined the appetitive and aversive implications of viewing the color red in romance- and achievement-relevant contexts, respectively, but in all existing empirical work approach and avoidance behavior has been studied in separate tasks and separate experiments. Research is needed to directly test whether red influences the same behavior differently depending entirely on psychological context.

The present experiment was designed to put this premise to direct test …

Is Maternal Smoking During Pregnancy A Causal Environmental Risk Factor For Adolescent Antisocial Behavior? Testing Etiological Theories And Assumptions, Brian M. D'Onofrio, Carol A. Van Hulle, Jackson A. Goodnight, Paul J. Rathouz, Benjamin B. Lahey

Psychology Faculty Publications

Background—Although many studies indicate that maternal smoking during pregnancy (SDP) is correlated with later offspring antisocial behavior (ASB), recent quasi-experimental studies suggest that background familial factors confound the association. The present study sought to test alternative etiological hypotheses using multiple indices of adolescent ASB, comparing differentially exposed siblings, and testing assumptions in the sibling-comparison design.

Considering Ethnicity And Gender Effects In Disgust Propensity And Spider And Snake Phobia: Comparing Asian Americans And European Americans, Laura L. Vernon, Michiyo Hirai

Psychological Science Faculty Publications

This study examined ethnic and gender differences and ethnicity by gender interactions in disgust propensity, spider and snake phobic distress, and their interrelationships. A main effect for ethnicity was found, with Asian Americans (n = 219) reporting more disgust propensity and phobic distress than European Americans (n = 581). Gender effects were modified by ethnicity by gender interactions, with European American males reporting the least disgust propensity and distress, and gender differences present only for European Americans. For both ethnic groups, phobic distress scores were strongly correlated with animal and non-animal disgust propensity. In hierarchical regression analyses, animal disgust propensity …

The Effects Of Familiarity And Persuasion On Risk Assessment, Casey L. Smith

Doctoral Dissertations and Master's Theses

Cognitive biases influence decisions and the analyses of risk. They are often derived from two separate processes: bias based on familiarity (familiarity bias) and bias as the result of influences from outside sources (persuasion bias). Research suggests that familiarity-based bias may lead to acceptance of an activity's drawbacks and a leniency of its risks.

In addition, research has tried to measure and analyze different types of biases individually, but few have compared the interactions of more than one bias at once. Because different biases may derive from different mental phenomena it is important to tease out the distinctions, and observe …

Memory Modulation In The Classroom: Selective Enhancement Of College Examination Performance By Arousal Induced After Lecture, Kristy A. Nielson, Timothy J. Arentsen

Psychology Faculty Research and Publications

Laboratory studies examining moderate physiological or emotional arousal induced after learning indicate that it enhances memory consolidation. Yet, no studies have yet examined this effect in an applied context. As such, arousal was induced after a college lecture and its selective effects were examined on later exam performance. Participants were divided into two groups who either watched a neutral video clip (n = 66) or an arousing video clip (n = 70) after lecture in a psychology course. The final examination occurred two weeks after the experimental manipulation. Only performance on the group of final exam items that …

A Comparison Of Relaxation Techniques On Blood Pressure Reactivity And Recovery Assessing The Moderating Effect Of Anger Coping Style, Catherine J. Mills

Psychology Theses & Dissertations

This study examined the relationship of anger coping style and relaxation techniques on cardiovascular reactivity and recovery in blood pressure (BP). Eighty-nine students from Eastern Virginia Medical School in Norfolk, Virginia participated. The participants were instructed to rest for ten minutes (baseline), complete a math task with harassment for 6 minutes (stressor), and engage in one of three recovery conditions (a standard control (SC), diaphragmatic breathing (DB), or mantra recitation (MR) without breathing instructions) for 10 minutes. The Spielberger State-Trait Anger Expression Inventory (STAXI) was utilized to measure trait anger coping style. Participants were compensated $25. It was hypothesized that …