Digital Commons Network^™

Resting-State Connectivity Identifies Distinct Functional Networks In Macaque Cingulate Cortex., R Matthew Hutchison, Thilo Womelsdorf, Joseph S Gati, L Stan Leung, Ravi S Menon, Stefan Everling

Brain and Mind Institute Researchers' Publications

Subregions of the cingulate cortex represent prominent intersections in the structural networks of the primate brain. The relevance of the cingulate to the structure and dynamics of large-scale networks ultimately requires a link to functional connectivity. Here, we map fine-grained functional connectivity across the complete extent of the macaque (Macaca fascicularis) cingulate cortex and delineate subdivisions pertaining to distinct identifiable networks. In particular, we identified 4 primary networks representing the functional spectrum of the cingulate: somatomotor, attention-orienting, executive, and limbic. The cingulate nodes of these networks originated from separable subfields along the rostral-to-caudal axis and were characterized by positive and …

The Kappa Opioid Agonist, Salvinorin A, Attenuates Locomotor Effects Of Morphine But Not Morphine-Induced Conditioned Place Preference, Stacy Dianne Engebretson

Masters Theses

Salvinorin A (SA), a selective kappa opioid receptor agonist, is the main psychoactive ingredient in the plant Salvia divinorum. The addiction potential of this naturally occurring hallucinogen is currently under investigation using well-validated preclinical screening procedures, including conditioned place preference (CPP). The primary aim of the current study was to determine the effects of SA on CPP established by morphine in adult rats. A secondary aim was to determine if the vehicle used to dissolve SA, dimethylsulfoxide (DMSO), influenced the outcome of SA place conditioning. Rats were randomly assigned to one of four treatment groups: morphine (10 mg/kg) vs. …

The Role Of Engagement Across Conceptually Distinct Treatment Elements For Social Anxiety Disorder, Timothy M. Emge

Department of Psychology: Dissertations, Theses, and Student Research

There are currently several efficacious treatments for social anxiety disorder (e.g. exposure therapy and cognitive therapy). Each of these treatments is thought to reduce symptoms of social anxiety by disrupting maintenance mechanisms of the disorder, yet mechanism of change research has not supported this view. The current study compared components from each therapy modality in order to better understand why symptoms reduce similarly between conceptually distinct treatments. Participants with high social anxiety were randomly assigned to give a speech with cognitive restructuring and engagement-enhancing procedures, cognitive preparation and video feedback, or a speech alone. Self-ratings of speech performance, confidence in …

I'M The Same Me: Communication And Renegotiation Of Identity In The Weight-Loss Surgery Experiences Of Women, Heather D. Schild

Masters Theses

Adult obesity rates are on the rise in the United States according to the Centers for Disease Control (2009) which has led to an increase in obesity-related illnesses such as diabetes and heart disease. Weight-loss surgery (WLS) has become accepted as a "cure" for obesity by the medical community. There has been a dramatic increase in the number of obese individuals electing to undergo WLS every year; 82% of these individuals are women (AHRQ, 2007). More women may be electing to undergo these procedures than men due to the pressures women face in American culture to achieve social standards of …

The Association Of Diet With Affect, Patricia Ann Ford

Loma Linda University Electronic Theses, Dissertations & Projects

Nutrients such as omega-3 fatty acids have been associated with mental health yet few studies have examined whether foods protective or deleterious for cardiovascular disease affect mood. The purpose of this study was to examine associations between consumption of foods typical of Mediterranean and Western diets and fatty acids with positive and negative affect.

Adventist church attendees residing in North America completed a validated food frequency questionnaire in 2002-6 as part of the Adventist Health Study-2. A subset of these participants ^=9,121) completed the Positive and Negative Affect Schedule (PANAS) in the Biopsychosocial Religion and Health Study conducted in 2006-7. …

Enhancement And Suppression Of Ultradian And Circadian Rhythms Across The Female Hamster Reproductive Cycle, Brian J. Prendergast, Annaliese K. Beery, Matthew J. Paul, Irving Zucker

Neuroscience: Faculty Publications

The impact of ovarian hormones on hamster ultradian rhythms (URs) is unknown. We concurrently monitored URs and circadian rhythms (CRs) of home cage locomotor activity during the estrous cycle, pregnancy, and lactation of Syrian hamsters. URs with a mean period of 4–5 h were evident during the dark phase in more than 90% of females on days 1 and 2 of the estrous cycle but were significantly less prevalent on cycle days 3 and 4. The period of the UR did not vary as a function of estrous cycle stage, but at all stages, the UR period was longer in …

Exposure To Potentially Traumatic Events, Emotional Adjustment, And Social Competence In Preschoolers Facing Economic Risk, Hillary Hurst

Graduate Masters Theses

The current study examined the relationship between exposure to potentially traumatic events (PTEs), emotional adjustment, and social competence in a sample of economically-disadvantaged, racially and ethnically diverse preschool-aged children (n=63; 60% female; average age = 52 months, S.D. = 10.30, range: 36-74 months). In this cross-sectional study, primary relationships between exposure to PTEs and emotional adjustment, and exposure to PTEs and social competence were examined. Additionally, parent affective symptoms were tested as a moderator of the relationship between child exposure to PTEs and emotional adjustment, and emotional adjustment was tested as a moderator of the relationship between child exposure to …

Genetic Contributions To The Midsagittal Area Of The Corpus Callosum, Kimberley A. Phillips, J. Rogers, E. A. Barrett, D. C. Glahn, P. Kochunov

Psychology Faculty Research

The degree to which genes and environment determine variations in brain structure and function is fundamentally important to understanding normal and disease-related patterns of neural organization and activity. We studied genetic contributions to the midsagittal area of the corpus callosum (CC) in pedigreed baboons (68 males, 112 females) to replicate findings of high genetic contribution to that area of the CC reported in humans, and to determine if the heritability of the CC midsagittal area in adults was modulated by fetal development rate. Measurements of callosal area were obtained from high-resolution MRI scans. Heritability was estimated from pedigree-based maximum likelihood …

The Impact Of Mindfulness On Exposure And Extinction Processes In Social Anxiety, Michael Treanor

Graduate Doctoral Dissertations

The present study sought to examine the potential impact of brief mindfulness inductions to enhance exposure and extinction processes in social anxiety. Mindfulness may enhance extinction through increased awareness of multiple conditioned excitors (thereby "overpredicting" the occurrence of an aversive outcome) or by acting as a retrieval cue to mitigate return of fear. Twenty-two participants high in social anxiety were recruited to participate in a series of massed exposures. Latent growth curve analyses revealed that participants who received mindfulness inductions prior to exposure procedures demonstrated enhanced extinction learning as measured by expectancy ratings, but not when measured by distress, state …

The Antihero In Popular Culture: A Life History Theory Of The Dark Triad, Peter K. Jonason, Gregory D. Webster, David P. Schmitt, Norman P. Li, Laura Crysel

Research Collection School of Social Sciences

The Dark Triad of personality is composed of narcissism, psychopathy, and Machiavellianism. Despite the common belief that these traits are undesirable, the media is awash with characters that embody the Dark Triad. Characters like Gregory House, M.D., Batman (a.k.a. the Dark Knight), and James BOND all embody these traits and are some of the most popular media franchises today. As entertaining as these characters are, they provide us with a window into the dark side of human nature. Instead of treating the dark side of human nature as inherently maladaptive, we provide an alternative view that, despite their costs, traits …

Religiosity, Knowledge Of Evolution, And Political Ideology As Predictors Of Attitudes Towards The Evolution V. Creationism Controversy, Nikolaus Philip Schuetz

Theses (6 month embargo)

Since Darwin On the Origin of Species over 150 years ago, evolution via natural selection has gained essentially unilateral support among scientists, with 97% of scientists agree that life evolved over time, while a mere 12% to 29% of the general public accepts evolution via natural selection. About three-quarters of the public support teaching creationism in public school science classes--a violation of the First Amendment--and a recent survey shows that just 28% of high school biology teachers advocating for evolution in their classroom, as per the national guidelines.

The present study aims to investigate and clarify certain relationships that lead …

Effect Of Nicotine On Body Composition, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.

Irruptions Of The Sacred In A “World Of Shit”: Profanity, Sacred Words, And Cinematic Hierophanies In Stanley Kubrick’S Full Metal Jacket (1987), Joseph E. Bisson

Journal of Religion & Film

Full Metal Jacket remains embedded in the consciousness of the popular culture mainly because of its abundance of profane language, violent imagery, and salacious set pieces. The juxtaposition of profane language and imagery with sacred language and religious symbolism reveals that Kubrick’s Vietnam film has powerful religious overtones that comprise an important element of the film’s critique of homo religiosus and the modern human condition. By continually juxtaposing the sacred and profane, Kubrick created “cinematic hierophanies” that advanced a cultural critique that inventively integrated ideas from some of the mid-20^th Century’s greatest interpreters of myths -- Carl Jung, Joseph …

Levels Of Altruism, Martin Zwick, Jeffrey Alan Fletcher

Systems Science Friday Noon Seminar Series

The phenomenon of altruism extends from the biological realm to the human sociocultural realm. This paper sketches a coherent outline of multiple types of altruism of progressively increasing scope that span these two realms and are grounded in an ever-expanding sense of “self.” Discussion of this framework notes difficulties associated with altruisms at different levels. It links scientific ideas about the evolution of cooperation and about hierarchical order to perennial philosophical and religious concerns. It offers a conceptual background for inquiry into societal challenges that call for altruistic behavior, especially the challenge of environmental and social sustainability.

This talk was …

'I Am Rooted, But I Flow': Virginia Woolf And 20th Century Thought, Emily Lauren Hanna

Scripps Senior Theses

My thesis is about Virginia Woolf’s novels, Mrs. Dalloway, The Waves, and To the Lighthouse. I examine these novels in relation to the theories of Henri Bergson, William James, and Sigmund Freud, and the groundwork of Modernism. I relate Woolf's use of water imagery and stream of consciousness technique to Bergson’s theory of “la durée,” or psychological, subjective time, James’ “stream of consciousness” theory in psychology, and Freud’s theory of the “oceanic” feeling of religious experience.

Debunking Misconceptions: Do Jury Instructions Influence Comprehension And Verdict Selection, Aryssa Z. Washington

Psychology Theses

The purpose of this study was to compare the efficacy of jury instructions that debunk common misconceptions versus standard instructions, with regards to verdict choice, comprehension of the legal standard, and reasoning used to support verdict decisions. A case summary was read by 159 participants who then listened to auditory instructions from a judge regarding the legal standards for second degree murder and voluntary manslaughter. They then completed measures assessing verdict, comprehension, and reasoning. While the results revealed that the legal instructions did not influence participants’ verdicts or comprehension of the legal standard, the data suggests that participants may have …

The Effects Of Rhes, A Striatal Specific Protein, On The Expression Of Behavioral And Neuropathological Symptoms In A Transgenic Mouse Model Of Huntington's Disease, Brandon A. Baiamonte

LSU New Orleans Theses and Dissertations

Huntington's disease (HD) is a neuropsychiatric disorder characterized by choreiform movement of the limbs, cognitive disability, psychosis and dementia. It is untreatable, incurable, and ultimately fatal. HD is invariably associated with an abnormally long CAG expansion within the IT15 gene on human chromosome 4. Although the mutant huntingtin protein (mHtt) is ubiquitously expressed in HD patients, cellular degeneration occurs only in neurons within the striatum and cerebral cortex. The Ras homolog Rhes is expressed very selectively in the precise brain areas affected by HD. Recent work using cultured cells suggests that Rhes may be a co-factor with mHtt in cell …

Of Mice And Mozart: Testing Spatial Reasoning And Memory Of Rats, Kaitlin O'Toole

Honors Theses

An increase in spatial-temporal reasoning has been documented in the presence of Mozart's sonata K.448; this enhancement of physical and psychological activities is called the "Mozart Effect" (Hughes 2001). This effect has been recorded in humans and animals alike, and its influence reaches a myriad of applications including calming wild animals to increasing test scores in college students to lowering high blood pressure. Using a cheeseboard apparatus to test spatial reasoning in rats, this experiment recorded the results from maze tasks completed in the presence of sonata K.448 compared to trials completed in silence. Results showed a significant difference between …

Using Brain Research To Aid Reading Comprehension, Mia Alyssa Claretto

Undergraduate Honors Thesis Collection

"Does it matter to learning if we pay attention? ...You bet it does" (Medina, 2007, p. 74). Studies John Medina, Richard Mayer, and numerous others prove the more attention the brain gives to a certain stimulus results in better retention of the information due to the fact that the information is more elaborately encoded. The more attention grabbing something is, the more emotion that is involved, means the better that information is remembered. As a future teacher, this detail has many implications for me. If I want students who are learning, then I need to design lessons that invite the …

Various Gaits Of African Elephant Calves, Elizabeth Anne Jennings

Undergraduate Honors Thesis Collection

It is commonly believed that elephants exhibit only one gait, a lateral sequence walk. However, recently there have been several interesting studies on the footfall patterns of adult African elephants (Loxodonta africana). Scientists have recognized that elephants actually exhibit two patterns of locomotion: a lateral sequence walk and an amble. The amble is a slight modification of the lateral sequence gait. The present study extends this work by examining the relationship between gait and speed in African elephant calves at the Indianapolis Zoo. I collected frame-by-frame observational video data from a newborn calf born at the Indianapolis Zoo across a …

The Relationship Between Resistance To Conformity And College Students’ Alcohol Use, Alcohol-Related Consequences Experienced, And Pbs Use, Melissa Ambrosino

Honors Theses

College students’ alcohol use has reached alarming heights in the past 25 years and shows no signs of slowing; experiencing alcohol-related negative consequences is on the rise for this demographic. Protective behavioral strategies (PBS) can help prevent negative consequences. This study sought to determine if relationships existed between resistance to conformity and college students’ alcohol consumption, alcohol-related negative consequences experienced, and PBS use. Data were collected via online surveys from students at a Southeastern mid-sized university. As hypothesized, resistance to conformity had negative relationships with alcohol consumption (r = -.094, p = .05 ) and number of alcohol-related negative …

Perceived Control And Adjustment: A Comparison Of Bereavement And Relationship Dissolution, Sara B. Greenberg

Honors Scholar Theses

The current study investigates the relationship between perceived control and adjustment across a comparison of two events; bereavement (n = 83) and relationship dissolution (n = 75). These events occurred in the six months prior to the study. Perceived control was assessed in terms of personal control, control of other forces, and control of a higher power, and how much control each had over the loss experienced. Adjustment was assessed in terms of current symptoms of distress (i.e., intrusion and avoidance), stress-related growth, positive states of mind, and life satisfaction. The relations between perceived control and adjustment differed …

Young Black Children's Representations Of The Father Figure In Low-Income Households, Shawnae Shalae Thompson

Honors Scholar Theses

This study investigated the cognitive-emotional schemas surrounding the father role in 50 young, low-income, Black children in relation to the amount of father involvement in the first 5 years of their lives. These representations were framed within four parenting categories: Nice, Mean, Authoritative, and Authoritarian. Diana Baumrind’s parenting style framework was utilized to create the Authoritative and Authoritarian parenting categories. This question was investigated in low-income families; the impact of gender of the child was also considered. Information on fathers’ involvements in the children’s lives were gathered through interviews and self-reports from the children’s fathers and mothers. Story Stem Narrative …

Ketamine Can Disrupt Episodic Memory (Hours To Days) Consolidation: Effects Of Varying Dose And Retention Intervals, Ryan Darius Tabtabai

Honors Scholar Theses

Memory consolidation is the process wherein short-term, episodic memories are converted into stable, long-term representations. Forebrain N-methy-d-aspartate receptors (NMDARs), particularly frontal cortical and hippocampal receptors, are thought to play a key role in neuronal plasticity and memory consolidation. Ketamine is an NMDA antagonist that disrupts memory, particularly encoding and retrieval processes. Previously we have observed no effect of post-acquisition ketamine treatment (50-100 mg/kg) on memory consolidation in rats performing a delayed-match-to place radial water maze task. The current study reexamined the effects of ketamine (25-100 mg/kg) on memory consolidation in this task over varying retention intervals (4, 24, and 48 …

Honors Retention: The Persistence Of Juniors And Seniors In The Honors Program Through Examination Of Commitment To Completion Of Honors Thesis, Amy A. Holland

Honors Scholar Theses

The goal of the Honors Program is to engage intellectually stimulated students in a unique, challenging experience culminating in the writing of an undergraduate thesis, a piece of scholarly work. The four elements to the mission of the Honors Program include challenging academics, a scholarly environment, a supportive community, and on-campus engagement. This study conducted a qualitative assessment of the Honors Program through written questionnaires and oral interviews of ten juniors or seniors either completing an Honors Thesis or not committed to the Thesis. This research did not find significant differences between these two groups due in part to small …

Childhood Sexual Abuse And Social Functioning: A Systematic Review Of Reviews, Evan Alden Leclair

Honors Scholar Theses

Childhood Sexual Abuse (CSA) has been widely studied for its effects in later life. Previous reviews of these studies have identified CSA as a risk factor for dysfunctions in later life such as risky sex, depression, teenage pregnancy, drug use, sexual re-victimization, and health disorders. This project systematically reviews the state of systematic reviews and meta-analyses addressing the link between CSA and social functioning in later life for men and women. Systematic reviewing and meta-analysis both apply scientific methods to gather and evaluate empirical evidence. The quality of reviews can vary, leaving the conclusions of poor reviews untrustworthy. The current …

Adenosine-Dopamine Interactions In The Open Field Arena: Studies Related To Locomotion And Anxiety, Rothem Kovner

Honors Scholar Theses

Nucleus accumbens dopamine (DA) is an important regulator of locomotion. The neuromodulator adenosine also has a role in regulating locomotion. The adenosine A_2A receptor subtype is colocalized with DA D2 receptors on medium spiny neurons in the striatum and nucleus accumbens. Interactions between adenosine A_2A and DA D2 receptor antagonists are significant for regulating various aspects of motor and motivational function. The adenosine A_2A antagonist MSX-3 has been shown to reverse the suppression of locomotion induced by the DA D2 antagonist eticlopride. The structure of MSX-3 was modified to produce the prodrug MSX-4 which has high oral …

Hippocampal Theta And Gamma: Effects Of Aging, Environmental Change, Cholinergic Activation And Learning, Matthew D. Howe

Honors Scholar Theses

During aging, hippocampal functioning is impaired; specifically aged humans and rats show reduced performance on spatial memory tasks. An age-related reduction in the neurotransmitter acetylcholine has been postulated to underlie this impairment. Rhythmic oscillations (theta, gamma) may serve to synchronize activity within the hippocampus and across the brain during learning; these may also change with aging.

To determine what aspects of oscillation are important for memory processing, the effects of aging, encountering a novel situation, learning a new task and cholinergic system activation (with physostigmine) were examined. Both age groups showed increased theta, but not gamma activity when encoding a …

Effort-Related Choice Behavior Is Affected By Pharmacological Manipulations Associated With Depression: The Effects Of Tetrabenazine, Megan Huizenga

Honors Scholar Theses

In humans, psychiatric symptoms such as anergia and psychomotor retardation reflect pathologies in behavioral activation. These motivational symptoms are fundamental aspects of depression and other disorders. Drugs such as reserpine and tetrabenazine deplete monoamines, including dopamine, and induce depressive like behaviors in humans. Our results indicate that administration of low doses of tetrabenazine can alter effort-related choice behavior, biasing animals towards low effort alternatives. These findings may be related to the ability of monoamine depleting agents such as tetrabenazine to blunt behavioral activation and induce psychomotor retardation, anergia and fatigue in humans, and this research could be useful for the …

Weight Concerns, Body Image, And Smoking Cessation In Pregnant Women In Rural Appalachia, Jennifer Aileen Correll

Electronic Theses and Dissertations

Smoking is the leading preventable cause of death, and smoking during pregnancy can lead to significant health complications for both the mother and developing child. In the Appalachian region of East Tennessee, pregnancy smoking rates are as high as 40% in some counties which is almost 4 times the national average. Weight and body image concerns have previously been identified as variables contributing to maintenance of smoking behavior. The current study was designed to examine the relationship between prepregnancy weight and body image concerns and smoking status at third trimester. Participants included 172 pregnant women who smoke. Women were recruited …