Digital Commons Network^™

In Vivo Efficacy Of Pyrantel Pamoate As A Post-Exposure Prophylactic For Rat Lungworm (Angiostrongylus Cantonensis), John Jacob, Argon Steel, Lisa Kaluna, Steven Hess, Israel Leinbach, Carmen Antaky, Robert Sugihara, Lindsey Hamilton, Peter Follett, Kathleen Howe, Steven Jacquier, Supakit Wongwiwatthananukit, Susan Jarvi

United States Department of Agriculture Wildlife Services: Staff Publications

Rat lungworm (Angiostrongylus cantonensis) is a neurotropic nematode, and the leading cause of eosinophilic meningitis worldwide. The parasite is usually contracted through ingestion of infected gastropods, often hidden in raw or partially cooked produce. Pharmaceutical grade pyrantel pamoate was evaluated as a post-exposure prophylactic against A. cantonensis. Pyrantel pamoate is readily available over-the-counter in most pharmacies in the USA and possesses anthelmintic activity exclusive to the gastrointestinal tract (GIT). Administering pyrantel pamoate immediately after exposure should theoretically paralyze the larvae in the GIT, causing the larvae to be expelled via peristalsis without entering the systemic circulation. In this study, pyrantel …

Current Ecotoxicity Testing Needs Among Selected U.S. Federal Agencies, Patricia Ceger, Natalia Garcia-Reyero Vinas, David Allen, Elyssa Arnold, Raanan Bloom, Jennifer C. Brennan, Carol Clarke, Karen Eisenreich, Kellie Fay, Jonathan Hamm, Paula F.P. Henry, Katherine E. Horak, Wesley Hunter, Donna Judkins, Patrice Klein, Nicole Kleinstreuer, Kara Koehrn, Carlie A. Lalone, James P. Laurenson, Jessica K. Leet, Anna Lowit, Scott G. Lynn, Teresa Norberg-King, Edward J. Perkins, Elijah J. Petersen, Barnett A. Rattner, Catherine S. Sprankle, Thomas Steeger, Jim E. Warren, Sarah Winfield, Edward Odenkirchen

United States Department of Agriculture Wildlife Services: Staff Publications

U.S. regulatory and research agencies use ecotoxicity test data to assess the hazards associated with substances that may be released into the environment, including but not limited to industrial chemicals, pharmaceuticals, pesticides, food additives, and color additives. These data are used to conduct hazard assessments and evaluate potential risks to aquatic life (e.g., invertebrates, fish), birds, wildlife species, or the environment. To identify opportunities for regulatory uses of non-animal replacements for ecotoxicity tests, the needs and uses for data from tests utilizing animals must first be clarified. Accordingly, the objective of this review was to identify the ecotoxicity test data …

Defining An Epidemiological Landscape That Connects Movement Ecology To Pathogen Transmission And Pace-Of-Life, Kezia Manlove, Mark Wilber, Lauren White, Guillaume Bastille-Rousseau, Anni Yang, Marie L.J. Gilbertson, Meggan E. Craft, Paul C. Cross, George Wittemyer, Kim M. Pepin

United States Department of Agriculture Wildlife Services: Staff Publications

Pathogen transmission depends on host density, mobility and contact. These components emerge from host and pathogen movements that themselves arise through interactions with the surrounding environment. The environment, the emergent host and pathogen movements, and the subsequent patterns of density, mobility and contact form an ‘epidemiological landscape’ connecting the environment to specific locations where transmissions occur. Conventionally, the epidemiological landscape has been described in terms of the geographical coordinates where hosts or pathogens are located. We advocate for an alternative approach that relates those locations to attributes of the local environment. Environmental descriptions can strengthen epidemiological forecasts by allowing for …

Relationships Between Covid-19 Infection Rates, Healthcare Access, Socioeconomic Status, And Cultural Diversity, Marghece P. J. Barnes

Boise State University Theses and Dissertations

The COVID-19 pandemic has had a disproportionate impact on racial and ethnic minority groups, with high infection rates throughout those communities. There are a complex set of factors that account for COVID-19 disparities. Focusing on infection and death rates alone without also examining health equity, underestimates the true impact of the pandemic. To gain a more clear understanding of COVID-19’s impact in these communities, we analyzed the relationship between state COVID-19 infection rates with social determinants of health: cultural diversity, health care access, and socioeconomic status. Our approach to identifying this relationship was to estimate infection rates by fitting John …

Developing Confidence And Interest In Teaching Relevant Mathematical Modeling Lessons, Jacy Beck

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

What is mathematical modeling and how can inservice and pre-service teachers develop the skills and competencies necessary to increase confidence and interest in teaching relevant mathematical modeling lessons? Mathematical modeling is “the process of choosing and using appropriate mathematics and statistics to analyze empirical situations, to understand them better, and to improve decisions” (CSSM, 2010, p. 72). By providing students with an opportunity to engage in relevant mathematical modeling prompts, we provide them with transferable skills and knowledge. The aim of this paper will be to provide insight into the relevance of teaching mathematical modeling, provide resources for integrating modeling …

Pesticide-Leaf Interactions And Their Implications For Pesticide Fate Modeling, Ashlie Kinross

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The work described here provides measured data to improve the understanding of the interaction between a pesticide and leaf surface after application. Two methods were developed, one using a newly introduced instrument, for the extraction of pesticides from leaves. This is required to measure the concentration of pesticide in the leaves. Using one of the developed extraction methods, measurements were made to determine how a pesticide equilibrates between a leaf and the air above it. These measurements were incorporated into a pesticide fate model that predicts how a pesticide moves through the environment after application to an agricultural field. The …

Mathematical Modeling Of Seir Model With Generalized Incidence Function And The Extension To Covid-19 Model, Shymaa Mohammad Dadoa

Theses

The COVID-19 pandemic had shown the importance of the SEIR model in predicting the outcome of the disease spread and to find the best strategies to contain the pandemic. As this type of model has a limited number of compartments, many other models were derived from the SEIR model to cover, to the maximum, the complex dynamics of the disease spread. These extensions of the SEIR model bring natural validity questions: How can we validate these models? and how far/close are these extended models from giving us real insights into the pandemic?

This thesis investigates the SEIR epidemic model and …

Pervasive Healthcare Internet Of Things: A Survey, Kim Anh Phung, Cemil Kirbas, Leyla Dereci, Tam Van Nguyen

Computer Science Faculty Publications

Thanks to the proliferation of the Internet of Things (IoT), pervasive healthcare is gaining popularity day by day as it offers health support to patients irrespective of their location. In emergency medical situations, medical aid can be sent quickly. Though not yet standardized, this research direction, healthcare Internet of Things (H-IoT), attracts the attention of the research community, both academia and industry. In this article, we conduct a comprehensive survey of pervasive computing H-IoT. We would like to visit the wide range of applications. We provide a broad vision of key components, their roles, and connections in the big picture. …

Spotted Fever Group Rickettsioses In Central America: The Research And Public Health Disparity Among Socioeconomic Lines, Kyndall C. Dye-Braumuller, Marvin S. Rodriguez Aquino, Stella C.W. Self, Mufaro Kanyangarara, Melissa Nolan Ph.D., Mph

Faculty Publications

Tick-borne diseases including rickettsial diseases are increasing in incidence worldwide. Many rickettsial pathogens can cause disease which is commonly underdiagnosed and underreported; Rickettsia pathogens in the spotted fever group (SFGR) are thus classified as neglected bacterial pathogens. The Central American region shoulders a large proportion of the global neglected disease burden; however, little is known regarding SFGR disease here. Although development varies, four of the seven countries in this region have both the highest poverty rates and SFGR disease burdens (El Salvador, Honduras, Guatemala, and Nicaragua), compared to Belize, Panama, and Costa Rica. Utilizing the Human Development Index (HDI), we …

The Thermodynamics Of A Stochastic Geometry Model With Applications To Non-Extensive Statistics, O.K. Kazemi, A. Pourdarvish, J. Sadeghi

Journal of Stochastic Analysis

No abstract provided.

Capturing The Pool Dilution Effect In Group Testing Regression: A Bayesian Approach, Stella Self Ph.D., Ms, Christopher Mcmahan, Stefani Mokalled

Faculty Publications

Group (pooled) testing is becoming a popular strategy for screening large populations for infectious diseases. This popularity is owed to the cost savings that can be realized through implementing group testing methods. These methods involve physically combining biomaterial (eg, saliva, blood, urine) collected on individuals into pooled specimens which are tested for an infection of interest. Through testing these pooled specimens, group testing methods reduce the cost of diagnosing all individuals under study by reducing the number of tests performed. Even though group testing offers substantial cost reductions, some practitioners are hesitant to adopt group testing methods due to the …

Optimising Response To An Introduction Of African Swine Fever In Wild Pigs, Kim M. Pepin, Vienna R. Brown, Anni Yang, James C. Beasley, Raoul Boughton, Kurt C. Vercauteren, Ryan S. Miller, Sarah N. Bevins

United States Department of Agriculture Wildlife Services: Staff Publications

African swine fever virus (ASFv) is a virulent pathogen that threatens domestic swine industries globally and persists in wild boar populations in some countries. Persistence in wild boar can challenge elimination and prevent disease-free status, making it necessary to address wild swine in proactive response plans. In the United States, invasive wild pigs are abundant and found across a wide range of ecological conditions that could drive different epidemiological dynamics among populations. Information on the size of the control areas required to rapidly eliminate the ASFv in wild pigs and how this area should change with management constraints and local …

Concerns With Taking The Covid-19 Vaccine, Kaela Bellamy, Robert S. Keyser

The Kennesaw Journal of Undergraduate Research

This IRB-approved descriptive study provides an overview of the concerns associated with receiving a COVID-19 vaccination within the Kennesaw State University community, an R2 university with over 41,000 students, and uses a survey to provide insight into how students, faculty, staff, and administrators are responding to the vaccinations for COVID-19, both available and unavailable, and their preferences. Our research findings indicate that: 1) Most of the population at Kennesaw State University intends to receive the vaccine, regardless of their concerns; 2) The majority of the participants who are either employed or provided an education by Kennesaw State University plan to …

Spatio-Temporal Models Of Infectious Disease With High Rates Of Asymptomatic Transmission, Aminur Rahman, Angela Peace, Ramesh Kesawan, Souparno Ghosh

Department of Statistics: Faculty Publications

The surprisingly mercurial Covid-19 pandemic has highlighted the need to not only accelerate research on infectious disease, but to also study them using novel techniques and perspectives. A major contributor to the dificulty of containing the current pandemic is due to the highly asymptomatic nature of the disease. In this investigation, we develop a modeling framework to study the spatio-temporal evolution of diseases with high rates of asymptomatic transmission, and we apply this framework to a hypothetical country with mathematically tractable geography; namely, square counties uniformly organized into a rectangle. We first derive a model for the temporal dynamics of …

Amplification Of Black Vulture (Coragyps Atratus) Dna From Regurgitated Food Pellets, Daniel R. Taylor, Bryan M. Kluever, John S. Humphrey, Iona M. Hennessy, Amber Sutton, William E. Bruce, Antoinette J. Piaggio

United States Department of Agriculture Wildlife Services: Staff Publications

Studies that rely on noninvasive collection of DNA for birds often use feces or feathers. Some birds, such as vultures, regurgitate undigested matter in the form of pellets that are commonly found under roost sites. Our research demonstrates that regurgitated pellets are a viable, noninvasive source of DNA for molecular ecology studies of vultures. Our objectives were to amplify 5 microsatellite loci designed for distinguishing Turkey Vultures (Cathartes aura) and Black Vultures (Coragyps atratus) in a single, multiplexed PCR, and to determine how long the target nuclear DNA persists after a vulture pellet is regurgitated and …

Digital Contact Tracing And Privacy, Mahdi Nasereddin, Edward J. Glantz, Galen A. Grimes, Joanne Peca, Michelle Gordon, Mike Bartolacci

Journal of Cybersecurity Education, Research and Practice

Digital contact tracing tools were developed to decrease the spread of COVID-19 by supplementing traditional manual methods. Although these tools have great potential, they were developed rather quickly resulting in tools with varying levels of success. The main issues with these tools are over privacy and who might have access to the information gathered. In general, their effectiveness varied globally, where users expressed privacy concerns associated with sharing identity, illness, and location information. This paper reviews these issues in deployments across Asia, Europe, and the United States. The goal is to begin a discussion that improves the design and development …

Seasonal Climatic Niche And Migration Movements Of Double-Crested Cormorants, D. Tommy King, Guiming Wang, Fred L. Cunningham

United States Department of Agriculture Wildlife Services: Staff Publications

Avian migrants are challenged by seasonal adverse climatic conditions and energetic costs of long-distance flying. Migratory birds may track or switch seasonal climatic niche between the breeding and non-breeding grounds. Satellite tracking enables avian ecologists to investigate seasonal climatic niche and circannual movement patterns of migratory birds. The Double-crested Cormorant (Nannopterum auritum, hereafter cormorant) wintering in the Gulf of Mexico (GOM) migrates to the Northern Great Plains and Great Lakes and is of economic importance because of its impacts on aquaculture. We tested the climatic niche switching hypothesis that cormorants would switch climatic niche between summer and winter …

Evaluation Of Silver Nanoparticles Attached To Methylene Blue As An Antimicrobial Agent And Its Cytotoxicity, Somon Hakimov

Masters Theses & Specialist Projects

Antibiotics resistance is considered as one of the greatest public health challenges of our time. In this work, we have synthesized silver nanoparticles (Ag NPs) using pulsed liquid ablation in different medium of growth and later combined with methylene blue (MB) to evaluate its potential as an effective photodynamic therapy agent. Ag NPs were synthesized by pulsed laser ablation technique in Polyvinylpyrrolidone (PVP), citrate, and Polyvinyl alcohol (PVA). The Ag NPs were characterized using transmission electron microscopy (TEM), UV-Visible (UV-Vis), and photoluminescence (PL) spectra. Next, Ag NPs were coupled with MB and used to deactivate the Gram-negative bacteria, Escherichia coli …

The Effect Of Resampling On Classifier Performance: Anempirical Study, Utomo Pujianto, Muhammad Iqbal Akbar, Niendhitta Tamia Lassela, Deni Sutaji

Knowledge Engineering and Data Science

An imbalanced class on a dataset is a common classification problem. The effect of using imbalanced class datasets can cause a decrease in the performance of the classifier. Resampling is one of the solutions to this problem. This study used 100 datasets from 3 websites: UCI Machine Learning, Kaggle, and OpenML. Each dataset will go through 3 processing stages: the resampling process, the classification process, and the significance testing process between performance evaluation values of the combination of classifier and the resampling using paired t-test. The resampling used in the process is Random Undersampling, Random Oversampling, and SMOTE. The classifier …

Comparative Susceptibility Of Eastern Cottontails And New Zealand White Rabbits To Classical Rabbit Haemorrhagic Disease Virus (Rhdv) And Rhdv2, Fawzi Mohamed, Thomas Gidlewski, Mary L. Berninger, Heather M. Petrowski, Alexa J. Bracht, Carla Bravo De Rueda, Roger W. Barrette, Meredith Grady, Emily S. O'Hearn, Charles E. Lewis, Karen E. Moran, Tracy L. Sturgill, Lorenzo Capucci, J. Jeffrey Root

United States Department of Agriculture Wildlife Services: Staff Publications

Rabbit haemorrhagic disease virus (RHDV) is associated with high morbidity and mortality in the European rabbit (Oryctolagus cuniculus). In 2010, a genetically distinct RHDV named RHDV2 emerged in Europe and spread to many other regions, including North America in 2016. Prior to this study it was unknown if eastern cottontails (ECT(s); Sylvilagus floridanus), one of the most common wild lagomorphs in the United States, were susceptible to RHDV2. In this study, 10 wild-caught ECTs and 10 New Zealand white rabbits (NZWR(s); O. cuniculus) were each inoculated orally with either RHDV (RHDVa/GI.1a; n = 5 per species) or RHDV2 (a recombinant …

Solar Radiation And Soil Moisture Drive Tropical Forest Understory Responses To Experimental And Natural Hurricanes, J. Aaron Hogan, Joanne M. Sharpe, Ashley Van Beusekom, Sarah Stankavich, Samuel Matta Carmona, John E. Bithorn, Jamarys Torres-Díaz, Grizelle González, Jess K. Zimmerman, Aaron B. Shiels

United States Department of Agriculture Wildlife Services: Staff Publications

Tropical forest understory regeneration occurs rapidly after disturbance with compositional trajectories that depend on species availability and environmental conditions. To predict future tropical forest regeneration dynamics, we need a deeper understanding of how pulse disturbance events, like hurricanes, interact with environmental variability to affect understory demography and composition. We examined fern and sapling mortality, recruitment, and community composition in relation to solar radiation and soil moisture using 17 years of forest dynamics data (2003–2019) from the Canopy Trimming Experiment in the Luquillo Experimental Forest, Puerto Rico. Solar radiation increased 150% and soil moisture increased 40% following canopy trimming of experimental …

Wetlands As Social Ecological Systems, And Relationality In The Policy Domain, Pierre Horwitz

Research outputs 2022 to 2026

A wetland policy perspective based on social ecological systems accepts that wetlands are part of landwaterscapes, that people are part of wetland ecosystems, and that the health of wetlands and the health of people are interdependent, evidence of the close, reciprocal and indivisible relationships between nature and culture. These relationships are storied and place-based, associated with place attachment, and are representations of relational values. They are most easily located wherever and whenever Indigenous and local peoples’ knowledge and interests are at play in wetland settings. Legal and administrative processes that recognise Chthonic law and rights for wetlands will elevate relational …

Phytochemical, Antibacterial, Antifungal, And Hemagglutination Screening Of Quercus Agrifolia Nee Root Extracts, Abdul Wahab, Arshad Farid, Muhammad Muzammal

Makara Journal of Science

In the current study, the roots of Quercus agrifolia Nee were subjected to phytochemical analysis to determine the presence of various compound groups. To explore the effect of Quercus agrifolia Nee roots, we evaluated four solvent extracts, namely, crude ethanolic extract (CEE), n-hexane, chloroform (CHCl₃), and ethyl acetate (EtOAc), for their antibacterial, antifungal, and hemagglutination activities. Agar well diffusion and agar tube dilution methods were used to determine the antibacterial and antifungal effects, respectively, and hemagglutination activity was measured against human erythrocyte blood groups. The qualitative phytochemical analysis of the solvent extracts of Quercus agrifolia Nee roots …

Jatropha Tanjorensis A Flora Of Southeast Nigeria: Isolation And Characterization Of Naringenin And Validation Of Bio-Enhanced Synergistical Activity Of Α- Tocopherol Toward Clinical Isolates Of Resistant Bacterial, Ikechukwu Kingsley Ijoma, Vincent Ishmael Egbulefu Ajiwe

Makara Journal of Science

Jatropha tanjorensis is among the rich floras of Southeast Nigeria and used by ethnic people to treat infections and manage health conditions. Ethnomedicine has long been employed in the treatment of ailments caused by bacterial pathogens. Studies showed that the incorporation of synthetic α-tocopherol to an antibacterial agent improves its activity. However, knowledge about the antibacterial-enhanced activity of plant-based α-tocopherols, especially those isolated from Jatropha tanjorensis, is limited because of the different bioactivities of synthetic and natural α-tocopherols. To determine the phytochemicals in J. tanjorensis, we carried out the structural elucidation of its leaf extracts. Naringenin and α-tocopherol …

A Mathematical Model And Sensitivity Analysis Of Lassa Fever With Relapse And Reinfection Rate, Latifat M Erinle-Ibrahim, Olukayode Adebimpe, Waheed O Lawal, Joshua O Agbomola

Tanzania Journal of Science

In this research paper, we depict an unprecedented four-dimensional ordinary differential equation modeling the dynamic transmission of the Lassa fever virus incorporating relapse and reinfection rate. Recent studies showed that the recovered individuals from Lassa fever can again be susceptible; which contradicted the common assumptions made by different researchers on modeling of Lassa fever. So, this article corrects and states the implications of the assumptions on the population density. The numerical simulations unveil the effect of relapse, reinfection, and treatment rate in the affected population. Performing sensitivity analysis suggests all new incorporated parameters can impact the infection dynamics substantially. The …

Mathematical Model Of Covid-19 Transmission Dynamics With Double Dose Vaccination, Tawakalt A Ayoola, Mutairu K Kolawole, Amos O Popoola

Tanzania Journal of Science

This research attempted to investigate the effects of double dose vaccination in a non-linear mathematical model of Covid-19 infections with special compartments class termed first and second dose vaccination. The basic reproduction number was obtained, the stability of the model was analyzed, and the sensitivity analysis was also carried out. Of interest is the numerical simulation of the model where the impacts of contact rate, first and second dose vaccination were studied. The obtained results recommended how to control the corona virus keeping in mind the contact rate and vaccination. Keywords:   Covid-19, Double dose Vaccination, Basic Reproduction Number, Global Stability

Antibiotic-Resistant Escherichia Coli And EnterococcusSpp. In Sand And Water At Tampa Bay Beaches, Jennifer K. Sabater

USF Tampa Graduate Theses and Dissertations

As antibiotic resistance in the environment continues to rise there is an increased concern that infections may become harder to treat as bacteria acquire genes for multidrug resistance. Recreational beach waters in the Tampa Bay area are routinely monitored by the Florida Department of Environmental Protection for the presence of fecal indicator bacteria (FIB) such as Escherichia coli and enterococci. Exceedances of beach action values (BAV) 235 CFU/100 mL (E. coli) and 70 CFU/100 mL (enterococci) indicate the presence of fecal contamination which is associated with an increased risk of disease for beachgoers. Antibiotic-resistant E. coli and Enterococcus spp. have …

Chronological Accumulation Of Microplastics In The Gulf Of Mexico And Their Acute Effects On Coral Bleaching, Martina M. Plafcan

USF Tampa Graduate Theses and Dissertations

Microplastics have accumulated in the environment since plastic production began. They have spread to all areas of the globe from marine trenches to mountains and they can be harmful to organisms. However, research on microplastics has only recently begun so it is unclear how they have changed over time in many regions of the ocean and how current oceanic concentrations might affect marine life. Additionally, organisms such as corals are under stress and have been declining due to climate change, so it is not yet known if microplastics exacerbate these threats. My thesis addressed these gaps in the literature by …

Constructing Green Gdp Evaluation System By Using Think Tank Double Helix Methodology, Hongbing Wang, Yijun Liu, Dawei Song

Bulletin of Chinese Academy of Sciences (Chinese Version)

In the new development stage, taking green GDP as the starting point for the development of green economy, low-carbon economy, and circular economy and an important indicator to measure high-quality development, sustainable development, and modernization is an effective way to ensure the construction of "beautiful China", basically realize socialist modernization and achieve the goal of carbon neutrality. This study uses the double helix theory of think tank to innovate a new paradigm of green GDP research and broaden the research path of GDP evaluation system. In terms of epistemology, the think tank double helix methodology provides a new systematic perspective …

Factors Associated With Covid-19 Vaccine Intentions Among South Carolina Residents, Mufaro Kanyangarara, Lauren Mcabee, Virginie G. Daguise, Melissa Nolan Ph.D., Mph

Faculty Publications

Despite evidence of vaccine safety and efficacy, vaccine hesitancy remains a major global health threat. The COVID-19 vaccine has presented unique vaccine hesitancy concerns compared to parental vaccine hesitancy towards childhood vaccines. South Carolina (SC) is home to a largely conservative population and historically has some of the lowest vaccination coverage rates in the United States of America. The goal of the current study was to identify factors associated with COVID-19 vaccine intentions among SC residents. From November 2020 to September 2021, 300,000 invitations to participate in community testing and complete an online survey were mailed to randomly selected SC …