Fabrication Of Chemically-Functionalized 3dprinted Porous Scaffolds For Biomedical Applications, Eiman Hamed Alblooshi

Theses

Hard tissues, such as bone and teeth, are natural composites of collagen nanofibers that are reinforced by inorganic calcium phosphate Nano crystallites, in the form of nanocomposites. The interlocking between these components in hard tissues explains their unique characteristics. Bone is mainly classified into two major types; compact and cancellous depending on the extent of porosity. Fractures in the compact bone can be treated using bone fixation implants, such as rods, screws, and plates, or can be totally replaced by bone implants if complete substitution is required. Cancellous bone, on the other hand, is highly porous and its substitution with …

Ar-Based Simulation Interaction And Human Factor Assessment For Human Robot Cooperation Assembly Planning, Wang Qiang, Xiumin Fan, Qichang He, Wenmin Zhu

Journal of System Simulation

Abstract: To improve assembly efficiency, it has become a trend for traditional manual assembly workstations to be carried out human-robot collaboration transformation. To realize the safe and fast evaluation of the improvement scheme, a general human-robot collaboration simulation method and human factor evaluation method based on Augmented Reality are proposed. Four levels of human-robot collaboration assembly simulation are established. An interactive scheme between real human and virtual robot for visual detection, perception and feedback is established. A fuzzy comprehensive evaluation model of human physiological and psychological indicators for workstation design is constructed. The prototype system is developed. Taking the assembly …

Knowledge Network Embedding Of Transcriptomic Data From Spaceflown Mice Uncovers Signs And Symptoms Associated With Terrestrial Diseases, Amber M. Paul, Charlotte A. Nelson, Ana Uriarte Acuna, Ryan T. Scott, Atul J. Butte, Egle Cekanaviciute, Sergio E. Baranzini

Publications

There has long been an interest in understanding how the hazards from spaceflight may trigger or exacerbate human diseases. With the goal of advancing our knowledge on physiological changes during space travel, NASA GeneLab provides an open-source repository of multi-omics data from real and simulated spaceflight studies. Alone, this data enables identification of biological changes during spaceflight, but cannot infer how that may impact an astronaut at the phenotypic level. To bridge this gap, Scalable Precision Medicine Oriented Knowledge Engine (SPOKE), a heterogeneous knowledge graph connecting biological and clinical data from over 30 databases, was used in combination with GeneLab …

The Effects Of Endocrine Disrupting Chemicals On Plants, Christian Mathew Pridemore

Theses, Dissertations and Capstones

Endocrine disrupting chemicals (EDCs) are a diverse group of chemicals which can have a detrimental effect on human health, affecting any physiological body system sensitive to hormonal changes. Human exposure to EDCs is inevitable due to their prevalence in modern living; EDCs are integral compounds found in everyday items with which humans interact and ingest. These, along with other indirect avenues leading to EDC exposure, pose a threat to both human health and to the health of wildlife and agricultural environments. Studies on the effects of EDCs on plants can be substantially informative and necessary for progress towards solving the …

Adaptive Two-Stage Edge-Centric Architecture For Deeply-Learned Embedded Real-Time Target Classification In Aerospace Sense-And-Avoidance Applications, Nicholas A. Speranza

Browse all Theses and Dissertations

With the growing number of Unmanned Aircraft Systems, current network-centric architectures present limitations in meeting real-time and time-critical requirements. Current methods utilizing centralized off-platform processing have inherent energy inefficiencies, scalability challenges, performance concerns, and cyber vulnerabilities. In this dissertation, an adaptive, two-stage, energy-efficient, edge-centric architecture is proposed to address these limitations. A novel, edge-centric Sense-and-Avoidance architecture framework is presented, and a corresponding prototype is developed using commercial hardware to validate the proposed architecture. Instead of a network-centric approach, processing is distributed at the logical edge of the sensors, and organized as Detection and Classification Subsystems. Classical machine vision algorithms are …

Matters Of Biocybersecurity With Consideration To Propaganda Outlets And Biological Agents, Xavier-Lewis Palmer, Ernestine Powell, Lucas Potter, Thaddeus Eze (Ed.), Lee Speakman (Ed.), Cyril Onwubiko (Ed.)

Electrical & Computer Engineering Faculty Publications

The modern era holds vast modalities in human data utilization. Within Biocybersecurity (BCS), categories of biological information, especially medical information transmitted online, can be viewed as pathways to destabilize organizations. Therefore, analysis of how the public, along with medical providers, process such data, and the methods by which false information, particularly propaganda, can be used to upset the flow of verified information to populations of medical professionals, is important for maintenance of public health. Herein, we discuss some interplay of BCS within the scope of propaganda and considerations for navigating the field.

Optimal Adjustment Of The Human Circadian Clock In The Real World, Samuel Christensen, Yitong Huang, Olivia J. Walch, Daniel B. Forger

Mathematics Sciences: Faculty Publications

Which suggestions for behavioral modifications, based on mathematical models, are most likely to be followed in the real world? We address this question in the context of human circadian rhythms. Jet lag is a consequence of the misalignment of the body’s internal circadian (~24-hour) clock during an adjustment to a new schedule. Light is the clock’s primary synchronizer. Previous research has used mathematical models to compute light schedules that shift the circadian clock to a new time zone as quickly as possible. How users adjust their behavior when provided with these optimal schedules remains an open question. Here, we report …

Association Between Social Media Exposure To Food And Beverages With Nutrient Intake Of Female Adolescents, Cholida Adiba, Siti Fatimah Pradigdo, Martha Irene Kartasurya

Kesmas

Communication technology development has influenced adolescent food choices and intakes. This study aimed to investigate the association between social media exposure to food and beverage content and nutrient intake among female adolescents. The study was conducted in a cross-sectional design. The targeted population was 104 female students aged 14–18 years old at 'XY' High School in Semarang, Central Java, Indonesia. Eighty-one subjects were chosen by clustered random sampling. Data were collected by interviews using structured questionnaires and a 3x24-hour recall method. Data analyses were conducted by chi-square, Fisher exact tests, and logistic regression. The median and standard deviations of social-media, …

Human Health And Wellness In Space: A Review Of Common Effects, Current Research, And Methods Of Prevention, Sonnet Xu, Rajendra Persaud, Nazrul I. Khandaker, Jasmin Budhan

Publications and Research

Space poses a threat to space crew wellness, where microgravity, isolation, radiation, and other conditions exert strain on human health. This study explores the changes to the human body in space and how it contributes to major threats to health during spaceflights. The effects of the hostile environment of outer space are all examined here, along with resultant changes to behavior, physiology, and the difficulty of remote diagnosis for health treatment in space. This review also considers the implications to the human cartilage, brain, and eyes along with the various other hazards and physiological alterations.

Human health in space is …

Microgravity And Its Bearing With Space Flight-Related Research, Farhan Tanvir, Nazrul I. Khandaker, Rajendra Persaud, Jeff Guan

Publications and Research

This study investigates the unique properties and applications of microgravity in the context of spaceflight research. Understanding and harnessing the behaviors of a microgravity environment opens up the doors to long-term space travel and consequently, future missions to other planets within our solar system. More specifically, simulating and conducting experiments in microgravity environments helps us explore its effects on the various necessary tasks and behaviors that are carried out during spaceflight. The most immediate and pronounced effects of microgravity are on human physiology. In particular, studies have shown that prolonged exposure to microgravity can result in a 20% decrease in …

The Energy And Exergy Of Light With Application To Societal Exergy Analysis, Matthew Kuperus Heun, Zeke Marshall, Emmanuel Aramendia, Paul E. Brockway

University Faculty Publications and Creative Works

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The Energy and Exergy of Light with Application to Societal Exergy Analysis

A Systematic Mapping Study On The Risk Factors Leading To Type Ii Diabetes Mellitus, Karar N. J Musafer, Fahrul Zaman Huyop, Mufeed J Ewadh, Eko Supriyanto, Mohammad Rava

Karbala International Journal of Modern Science

Diabetes is one of the most common diseases that has had devastating effects on the general population. It is also among the most popular research trends in modern medicine. Thus, due to the complexity and desirability of this particular affliction, there is a lot of demand towards understanding this disease better, so that it can pave the way towards better solutions in combating diabetes. The aim of this review is to provide a categorization of the risk factors leading to Type II Diabetes. In order to provide a justification for the type of diabetes, an explanation is provided which covers …

Bentonite Reinforced Chitosan Scaffold: Effect Of Bentonite Exfoliation On Scaffold Properties, Soma Chakraborty, Cristine Joy M. Pimentel

Chemistry Faculty Publications

Chitosan is under investigation as biodegradable scaffolding material for tissue engineering. Crosslinked chitosan alone cannot form a self-supporting scaffold hence it needs reinforcement. The group reported fabrication of chitosan scaffolds reinforced by exfoliated and non-exfoliated bentonite and compared their properties. Scaffolds were fabricated by freeze-drying technique. Bentonite was exfoliated by allowing it to swell in water for a certain time interval. XRD profile showed that swelling reduced the crystallinity of bentonite. Both types of bentonite dispersed well in the chitosan matrix and imparted structural stability to the scaffolds. Scaffolds had interconnected pores, apparent porosity of scaffold with exfoliated bentonite was …

Relationship Between Humidity And Physiology In Warm And Humid Conditions: A Literature Review, Yuliya Dzyuban

Research Collection School of Social Sciences

Change in precipitation patterns caused by global warming will likely increase humidity in some areas of the world. Moreover, populations in tropical climates with already high humidity levels can experience an added stress on their health and thermal comfort due to an amplifying effect of heat and moisture. Humidity is a generic term commonly used to describe moisture in the air. However, there are numerous variables that describe different properties of humid air that can be used in scientific studies. While relative humidity remains the most used, it has several shortcomings associated with its high correlation with air temperature. Thus, …

Ronald E. Mcnair Scholars Program Profiles And Abstracts 2020, Mcnair Scholars Program

McNair Symposium

This is the complete event program and provides presentation abstracts and biographies of McNair scholars and their mentors.

The Role Of The Chaperone Cct In Assembling Cell Signaling Complexes, Nicole C. Tensmeyer

Theses and Dissertations

In order to function, proteins must be folded into their native shape. While this can sometimes occur spontaneously, the process can be hindered by thermodynamic barriers, trapped intermediates, and aggregation prone hydrophobic interactions. Molecular chaperones are proteins that help client proteins or substrates overcome these barriers so that they can be folded properly. One such chaperone is the chaperonin CCT, a large MDa protein made up of 16 paralogous subunits that form a double ring structure. CCT encapsulates its substrates in a central cavity, where they are sequestered and folded, using ATP binding and hydrolysis to drive conformational changes in …

Solvation Structures And Dynamics Of Small Molecules: Experimental And Computational Studies Using Carbonyl Vibrational Modes As Probe, Xiaoliu Zhang

LSU Doctoral Dissertations

Solutions are ubiquitous in both the global environment and the human body, and play a significant role in scientific research and industrial production. The structures and dynamics of solutions have been studied for centuries. However, conventional experimental methods, whose intrinsic measuring time is on the order of nanoseconds to microseconds, could not detect the fast dynamics taking place in the solution on the timescale of femto- and pico-second. In this dissertation, the ultrafast two-dimensional infrared (2DIR) spectroscopy was applied to characterize the structure and dynamics in three different types of solutions on the sub-picosecond timescale. Linear Fourier transform infrared spectroscopy …

A Pbpk Model For Clearance Of Pegylated Nanomedicines, Anne M. Talkington, Samuel K. Lai, M. Gregory Forest

Biology and Medicine Through Mathematics Conference

No abstract provided.

The Impact Of Forces On Knee Ligaments: A Biomechanical Analysis, Hannah Couture

Honors Projects in Science and Technology

Anatomy of the human body is complicated, and it impacts human physiology in every way, shape, and form. The application of physics in mechanical models creates simplified systems to help understand more complex structures. This paper looks at how anatomical research informed the creation of a two-dimensional computational model of the knee joint. The existing research and literature on the anterior cruciate ligament (ACL), the posterior cruciate ligament (PCL), the lateral collateral ligament (LCL), and the medial collateral ligament (MCL) is quite plentiful. The posterolateral corner (PLC), however is less studied in both anatomical research and its impact on surrounding …

Equivalency Testing For Two Formulations Of A Clinical Laboratory Control Material, Jessica M. Hart

Capstone Experience: Master of Public Health

Clinical laboratory control materials are an integral part of legally-mandated and highly regulated quality control protocols in all clinical laboratories. These controls ensure accurate performance of the laboratory testing and instrumentation used to produce medical test results for millions of patients. It is of clinical and public health interest to ensure the diagnostic test results which affect so many people are regulated by the most accurate and precise controls.

Formulation changes in control materials have the potential to impact laboratory quality control. In this study, data from two formulations of a hematology control were compared to assess equivalency of the …

On Characterizing Quantum Processes And Detectors, Kevin Valson Jacob

LSU Doctoral Dissertations

In 2009, physicists at the National Institute of Standards and Technology in Colorado, Boulder developed what could arguable be called the first rudimentary quantum computer [1]. The past decade has seen unprecedented improvements in quantum information science culminating in the demonstration of quantum supremacy --- that quantum computers can solve problems that are impractical to be solved on the best supercomputers [2]. This remarkable progress necessitates the development of techniques to characterize the quantum devices that are being developed. In my thesis, I will focus on such devices that manipulate and detect light.

In Chapter 1, I will introduce the …

Electronic Image Detectability Under Varying Illumination Conditions, Jeremy J. Miller

Theses and Dissertations

Light in the built environment plays an essential role in the vision and the health of humans through non-visual receptors in the eyes. Unfortunately, image analysts and other Air Force personnel who engage in the detection of objects on softcopy displays are often required to work in very dimly-lit or dark environments as higher illumination reduces the contrast of displayed information. Literature has shown that increases in light exposure improves circadian rhythm entrainment and reduces the negative health consequences of insufficient lighting. This research examines the effects of indoor lighting to determine if increases in ambient illumination or changes to …

Adapting To Extreme Heat: Social, Atmospheric, And Infrastructure Impacts Of Air Conditioning In Megacities - The Case Of New York City, Harold Gamarro

Dissertations and Theses

Extreme heat events are becoming more frequent and intense in most large cities. Built-up surfaces also limit cooling mechanisms, leading to warmer conditions in cities, a phenomenon called the Urban Heat Island (UHI). This presents major challenges to reduce adverse health effects of hot weather, particularly in vulnerable populations like the elderly and low-income communities. Here we explore the overall impacts of increasing air conditioning (AC) system adoption in residences as an adaptive measure to reduce human health risks under heat waves, with New York City (NYC) as a case study. This study uses AC adoption data from the 2017 …

Piezoresistive Disposable Weight Sensor With Increased Sensitivity, Kuter Erdi̇l, Tuğçe Ayraç, Ömer Gökalp Akcan, Yi̇ği̇t Dağhan Gökdel

Turkish Journal of Electrical Engineering and Computer Sciences

This study presents the design, simulation, implementation, and experimental characterization of a paperbased perforated disposable weight sensor system with a double piezoresistive layer. The demonstrated system is designed to achieve highly sensitive weight sensing operations with low-cost materials. For that purpose, the main fabrication material of the proposed disposable sensor is selected as a 289 $\mu$m thick Strathmore 400 series Bristol paper. Approximately 48 $\mu$m thick piezoresistive graphite paste is coated onto both sides of the paper-based cantilever beam with the aim of acquiring more sensitive weight-sensing capability. Additionally, the proposed paper-based structure has rows of closely spaced perforations at …

Electrospinning Piezoelectric Fibers For Biocompatible Devices, Bahareh Azimi, Mario Milazzo, Andrea Lazzeri, Stefano Berrettini, M. Jasim Uddin, Zhao Qin, Markus J. Buehler, Serena Danti

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

The field of nanotechnology has been gaining great success due to its potential in developing new generations of nanoscale materials with unprecedented properties and enhanced biological responses. This is particularly exciting using nanofibers, as their mechanical and topographic characteristics can approach those found in naturally occurring biological materials. Electrospinning is a key technique to manufacture ultrafine fibers and fiber meshes with multifunctional features, such as piezoelectricity, to be available on a smaller length scale, thus comparable to subcellular scale, which makes their use increasingly appealing for biomedical applications. These include biocompatible fiber-based devices as smart scaffolds, biosensors, energy harvesters, and …

A Comparative Study On The Monovalent And Divalent Cation Separation Of Polymeric Films And Membranes From Salt Solutions Under Diffusion-Dialysis, Serkan Acar, Hacer Yeşi̇m Cengi̇z, Ayça Ergün, Eymen Konyali, Hüseyi̇n Deli̇göz

Turkish Journal of Chemistry

This study deals with selective separation of mono- and divalent cations from aqueous salt solutions using polymeric films based on polyethylene (PE) and polyamide6 (PA6), and two different commercial nanofiltration (NF) membranes. The diffusion rates (D) of ions (Na$^{+}$ and Ca$^{2+})$, separation factors ($\alpha )$ and ion rejections (R) of the films and NF membranes are examined comparatively as well as their surface morphology and hydrophilicity. It is observed that the diffusion rates of Na$^{+}$are in the range of 0.7-1.8 $\times $ 10$^{-8}$cm$^{2}$.s$^{-1\, }$in the decreasing order of PE $>$ NF90 $>$ NF270 $>$ PA6 while Ca$^{2+\, …

Multimodal Mobile Sensing Systems For Physiological And Psychological Assessment, Nguyen Phan Sinh Huynh

Dissertations and Theses Collection (Open Access)

Sensing systems for monitoring physiological and psychological states have been studied extensively in both academic and industry research for different applications across various domains. However, most of the studies have been done in the lab environment with controlled and complicated sensor setup, which is only suitable for serious healthcare applications in which the obtrusiveness and immobility can be compromised in a trade-off for accurate clinical screening or diagnosing. The recent substantial development of mobile devices with embedded miniaturized sensors are now allowing new opportunities to adapt and develop such sensing systems in the mobile context. The ability to sense physiological …

Building Datasets From Publicly Accessible Social Media Images For Biometric Analysis, Giordano Roberto Benitez Torres

Theses and Dissertations

The world is developing at a rapid pace, and some of its advancement can be accredited to technological innovations that are affecting many aspects of society. A field within computer science that is increasingly reaching many industries is Biometrics, specifically the area face recognition. Researchers, scientists, and organizations actively try to improve the performance of tools and algorithms. Nevertheless, for it to occur, there is a need for high-quality datasets to test and develop new techniques. Never had humanity, in the course of the history of civilization, produced massive amounts of data as it currently does. Social media networks play …

Emotion-Aware Chat Machine: Automatic Emotional Response Generation For Human-Like Emotional Interaction, Wei Wei, Jiayi Liu, Xianling Mao, Guibing Guo, Feida Zhu, Pan Zhou, Yuchong Hu

Research Collection School Of Computing and Information Systems

The consistency of a response to a given post at semantic-level and emotional-level is essential for a dialogue system to deliver human-like interactions. However, this challenge is not well addressed in the literature, since most of the approaches neglect the emotional information conveyed by a post while generating responses. This article addresses this problem by proposing a unified end-to-end neural architecture, which is capable of simultaneously encoding the semantics and the emotions in a post for generating more intelligent responses with appropriately expressed emotions. Extensive experiments on real-world data demonstrate that the proposed method outperforms the state-of-the-art methods in terms …

Paper-Based Flexible Electrode Using Chemically-Modified Graphene And Functionalized Multiwalled Carbon Nanotube Composites For Electrophysiological Signal Sensing, Md Faruk Hossain, Jae Sang Heo, John Nelson, Insoo Kim

Bioelectrics Publications

Flexible paper-based physiological sensor electrodes were developed using chemically-modified graphene (CG) and carboxylic-functionalized multiwalled carbon nanotube composites (f@MWCNTs). A solvothermal process with additional treatment was conducted to synthesize CG and f@MWCNTs to make CG-f@MWCNT composites. The composite was sonicated in an appropriate solvent to make a uniform suspension, and then it was drop cast on a nylon membrane in a vacuum filter. A number of batches (0%~35% f@MWCNTs) were prepared to investigate the performance of the physical characteristics. The 25% f@MWCNT-loaded composite showed the best adhesion on the paper substrate. The surface topography and chemical bonding of the proposed CG-f@MWCNT …