Digital Commons Network^™

Anti-Inflammatory And Insulin-Modulating Effects Of Tithonia-Curcuma-Moringa (Tcm) Formulation In Type 2 Diabetes: An Experimental Study In Mice, Rif’Atul Hawani Burhan, Nabila Shafa Yumna Salsabila, Devita Zulfa Pratama, La Tazkia Aulia Wibowo, Yulian Ervin Maulana, Moh Dliyauddin, Noviana Dwi Lestari, Agung Pramana Warih Marhendra, Aris Soewondo, Hideo Tsuboi, Muhaimin Rifa’I

Karbala International Journal of Modern Science

Type 2 diabetes is a chronic metabolic disorder characterized by hyperglycemia and chronic inflammation. This study investigated the anti-inflammatory and insulin-modulating effects of Tithonia-Curcuma-Moringa (TCM) formulation in type 2 diabetes model. Male BALB/c mice were divided into six groups: normal control, type 2 diabetes control, metformin treatment, and three TCM formulation treatment groups with three different dose combinations. Type 2 diabetes was induced using a high-fat diet combined with streptozotocin injection, supported by sucrose administration. After 21 days of treatment, the spleen and pancreas were isolated for flow cytometry analysis. The results showed that the expression levels of …

Cognitive Conflict In Iconic Visual Representations: Comparing Conventional And Ai Approaches, Endrayana Putut Laksminto Emanuel, Herfa Maulina Dewi Soewardini, Radhitya Duta Pradana, Sikky El Walida

Jurnal Pendidikan Sains

Background of study: The rapid integration of Artificial Intelligence (AI) in higher education has transformed mathematical problem-solving practices, yet it introduces potential discrepancies in students’ visual understanding, particularly in geometric contexts, leading to commognitive conflicts in visual mediators. Aims and scope of paper: This study aims to analyze and compare the sources of commognitive conflict in iconic visual representations when students solve flat shape problems using conventional methods versus AI-assisted approaches. Methods: A qualitative design was employed involving 20 first-year mathematics education students divided into two groups (AI-assisted and conventional). Data were collected through students’ written work and semi-structured interviews …

Research Status And Development Trend Of Acidification And Permeability Improvement Technology For Low-Permeability Coal Seam, Shaochuan Chen, Yun Lei, Fuchao Tian, Jie Kang

Journal of Sustainable Mining

Low-permeability coal seams in China are often characterized by mineral-clogged pore-fracture systems, severely limiting coalbed methane (CBM) extraction efficiency. Acidification technology, which involves injecting acidic solutions into coal seams to dissolve minerals and enhance permeability, has emerged as a promising approach. This paper systematically reviews the mechanisms, laboratory findings, and field applications of acidification technology for permeability enhancement in low-permeability coal seams. Key findings include significant improvements in pore connectivity, reductions in gas adsorption capacity, and enhanced gas extraction rates post-acidification. Field tests demonstrate that acid fracturing can increase gas extraction volume by 4-7 times. The study also identifies current …

Ais26s: Genai And Llms For Cybersecurity, Political Sciences, Transportation Security, And Resiliency, Latifur Khan

Paul English Applied Artificial Intelligence (AI) Institute Publications

This presentation examines the role of generative artificial intelligence (GenAI) and large language models (LLMs) in addressing complex challenges across cybersecurity, political science, and transportation security. Dr. Latifur Khan discusses how advanced AI methods can be applied to threat detection, data analysis, and decision-making in high-risk and data-intensive environments. The talk highlights interdisciplinary applications of LLMs, emphasizing their ability to extract insights from large-scale data, improve system resilience, and support intelligent infrastructure. Emerging research directions and practical implications for real-world deployment are also discussed.

Quantitative Analysis Of Cholera Dynamics And The Impact Of Integrated Control Measures., Kazeem Abidoye Odeyemi, Mutairu Kayode Kolawole

Tanzania Journal of Science

A comprehensive mathematical evaluation of cholera dynamics, emphasizing the crucial role of optimal control strategies which include vaccination, treatment in endemic region and environmental hygiene in controlling the disease spread in Western and Mid-Eastern regions of African setting. Through analysis of the local and global stability of the model and assessing the reproduction number (��0), this research highlights how targeted interventions can influence transmission rates of cholera disease. Sensitivity analysis identifies key parameters driving cholera dynamics, underlining the urgency of timely and adequate intervention. Utilizing the innovative Homotopy Perturbation Method for the numerical simulation, the study explores the interplay between …

Re: Conditional Approval Letter For Revised Clark Tailings Consolidated Waste Management Area (Ctcwma) Site Investigation Data Summary Report 2024 And Response To Epa Comment Letter (Dated February 24, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Empirical Benchmarks For Interpreting Effect Sizes In Violent Crime Interventions, Kohta James Matsukawa Hansen

Theses and Dissertations

Criminal justice researchers apply Cohen’s (1988) benchmarks to classify effect sizes as small, medium, or large, despite these standards never being meant for broad, decontextualized use (Cohen, 1988; Gies et al., 2024; Goulet-Pelletier & Cousineau, 2018; Lakens, 2013; Milner et al., 2023). Repeatedly doing so may weaken statistical validity, distort findings, and impede effective policymaking. This study introduces the first effect size benchmarks specifically designed for violent crime interventions.

Using a quasi-meta-analysis framework, 1,605 effect sizes from 104 violent crime intervention studies from the CrimeSolutions clearinghouse were converted to Cohen’s d. Three new discrete benchmarking methods were created using a …

Cytokinesis And Dbf2, Katharine Gray

Miners Solving for Tomorrow Research Conference

The Mitotic Exit Network (MEN) is a signaling pathway that allows a dividing cell to exit cytokinesis. Dbf2 is a MEN protein kinase in yeast, which provides a simplified model for studying this pathway. By altering Dbf2’s activity through phosphorylation mutants, its effect on cytokinesis can be studied. Transformed cells with a mutant and degron Dbf2 allele are prompted to destroy the degron Dbf2 protein, leaving only mutated Dbf2 behind. This allows for clear analysis of the effect of the phosphorylation mutant on division. Fluorescence microscopy can be used to visualise this degradation, and the impact on actin ring formation …

A Wearable Mxene-Based Sweat Sensor For Real-Time Monitoring Of Inflammatory Biomarkers, Ariel Pilger

Miners Solving for Tomorrow Research Conference

Many conventional biosensing approaches rely on invasive sampling or bulky benchtop instrumentation, limiting their use in continuous and portable applications. This project focuses on the development of wearable sweat-based biosensors that enable non-invasive, continuous, and portable monitoring of physical, chemical, and biological markers. The system will be designed to target markers present in sweat and transduce the biochemical interactions into measurable electrical signals. These signals will be processed through integrated electronics to produce clear, interpretable outputs for users and medical professionals. Supporting circuitry including filters, amplifiers, and an independent power supply will be implemented as necessary to ensure signal accuracy, …

The Effects Of Climate Change On Competition And Recovery From Disturbance In An Iconic Marine Community, Lauren Tibbits

Senior Theses

This paper explores how the recovery of populations of Semibalanus balanoides is affected by climate variation. In intertidal marine ecosystems, larval recruitment is important in shaping all ecological processes. S. balanoides is a cold-water barnacle species that is competitively dominant over Chthamalus montagui and C. stellatus, two warm-water species. This competitive interaction is well studied, though it is not understood how that competition influences the recovery of S. balanoides after a disturbance nor how this process varies over a temperature gradient. 19 sites were studied across the United Kingdom, spanning from northern Scotland to southwestern England. At each site, a …

A Guide To Environmentally Sustainable Filmmaking In South Carolina, Christina Vera Dobrowolski

Senior Theses

The entertainment industry has a massive environmental impact. This information is not new in the filmmaking world, as multiple mainstream efforts exist to curb the material-intensive production of live action films and TV. One of these efforts is the use of voluntary sustainable guidelines, which serve as tools that outline sustainable best practices and resources that can help achieve them. However, current guidelines often lack practicality— focusing more on altruism rather than core economic factors that ultimately drive filmmaking. This project aims to address that gap for filmmakers in South Carolina by offering a website featuring attainable, state-specific resources for …

Fingerprinting Voice Commands Of Vpn-Protected Smart Speakers, Xiaoguang Guo, Keyang Yu, Qi Li, Dong Chen

Computer Science Faculty Research and Publications

Extensive recent research has shown that it is surprisingly easy to infer Amazon Alexa voice commands over their network traffic data. To prevent these traffic analytics (TA)-based inference attacks, smart home owners are considering deploying virtual private networks (VPNs) to safeguard their smart speakers. In this work, we design a new machine learning-powered attack framework—VoiceAttack that could still accurately fingerprint voice commands on VPN-encrypted voice speaker network traffic. We evaluate VoiceAttack under 5 different real-world settings using Amazon Alexa and Google Home. Our results show that VoiceAttack could correctly infer voice command sentences with a Matthews Correlation Coefficient (MCC) of …

Phase 5 - Post Implementation, Anna Pugerud

Distinguished Student Scholarship Collection

This paper presents a post‑implementation analysis and system design plan for digitizing animal health records within the Animal Health Services (AHS) department. The project addresses inefficiencies, data inaccuracies, and physical storage limitations associated with paper‑based documentation by proposing the adoption of a Software as a Service (SaaS) digital records solution. Through stakeholder interviews, observations, and document analysis, the project identifies functional, non‑functional, and system requirements necessary to support streamlined reporting, treatment tracking, and regulatory compliance. The analysis outlines feasibility across technical, economic, and organizational dimensions, demonstrating that the proposed system can reduce documentation time, improve response times, and lower operational …

Navigating Sustainable Burial In Southern Nevada, Kristen Gibson

Calvert Undergraduate Research Awards

Navigating Sustainable Burial in Southern Nevada investigates the accessibility of environmentally conscious end-of-life options for individuals throughout the region. Sustainable burial practices, including green burial, water cremation, and natural organic reduction, provide alternatives to traditional burial and cremation methods. Research was conducted through an analysis of Nevada statutes, local reporting, funeral service resources, and public discussions related to sustainable burial. The research revealed that although Nevada expanded legal recognition of sustainable burial by legalizing natural organic reduction, public access to clear information and available services remains limited. These findings informed the creation of a choose-your-own-adventure booklet designed to translate legal …

Burnout Sentinel: An Early Warning System For Student Burnout Using Workload And Recovery Indicators, Minh Duy Do

Expo Student Presentations

2026 Spring Expo Video Essay Presentation

• Biological & Life Sciences
• Health Sciences & Health Professions
• Physical & Applied Sciences
• Service-Learning
• Social & Behavioral Sciences

Policy Design, And The Repeal Of Ghana’S Emissions Levy Act: A Multiple Streams Framework Analysis, Anthony Amotoe-Bondzie

Collected Student Papers

Ghana’s 2023 Emissions Levy Act (Act 1112) imposed charges on large industrial emitters and vehicles, intending to internalize pollution costs and raise government revenue. This study applies to Kingdon’s Multiple Streams Framework (MSF) to explain the policy’s rapid repeal. Drawing on legislative texts, official reports, and media accounts, it categorizes influences into the problem (rising living costs), policy (design features), and politics (stakeholder mobilization) streams. Key findings reveal that the levy’s mixed design, a per-ton CO₂ fee on industry combined with a flat vehicle ownership tax, undermined its climate rationale and appeared more as a revenue grab. Implementation gaps exacerbated …

Closing The Loop In Sustainable Fashion: Recycling Textile Waste And Its Environmental, Social, And Consumer Impacts, Anthony Amotoe-Bondzie

Collected Student Papers

Fast fashion has intensified textile waste, emissions, and social inequities across global supply chains. This study examines sustainable fashion frameworks and the role of textile recycling in advancing circularity. It employes a qualitative integrative literature review synthesizing interdisciplinary research on waste streams, recycling technologies, policy instruments, and consumer behavior. However, advanced recycling technologies offer environmental benefits but remain limited in scale. Nonetheless, rising consumption offsets efficiency gains, while economic and behavioral barriers hinder systemic change. Technological innovation alone is insufficient; circular design, regulatory enforcement, and reduced overproduction are essential for sustainable transformation.

Multi-Jurisdictional Hazard Mitigation Plan For Landslides For The Kentucky River Area Development District, Kentucky, Hudson J. Koch, Matt M. Crawford, Jason M. Dortch

Contract Reports--KGS

Landslides are a widespread and complex geologic hazard that affects people and infrastructure. The Kentucky River Area Development District, Kentucky, sustains relatively high landslide activity that impacts several municipalities in eastern Kentucky. This hazard mitigation planning project outlines landslide hazard and risk assessments for the Kentucky River Area Development District, with information needed for each community in the region to develop mitigation strategies that will support infrastructure and development needs, land-use planning, situational awareness, and response and recovery actions for the communities.

Corporate Fiduciary Duties And The Climate And Biodiversity Crisis, Eric W. Orts, Sandra G. Schafhäutle

Michigan Journal of Environmental & Administrative Law

This Article argues that addressing one of the most urgent environmental challenges facing humanity today—the global climate and biodiversity crisis—calls for a transformation at the heart of corporate law: its fiduciary duties. After demonstrating how current corporate fiduciary duties are implicated in this crisis, we argue for reform of fiduciary duties operating at two levels: those governing directors and officers of business corporations, and those governing institutional investors and asset managers. We then distinguish between two general kinds of corporate fiduciary duties: permissive and mandatory. We contend that corporate law should accommodate a more expansive understanding of fiduciary duties by …

Four Decades, No Progress: Time For A Columbia River Basin Compact, Liesl L. Bogaard

Michigan Journal of Environmental & Administrative Law

Since the Power Act’s passage in 1980, the government entities who develop and implement energy policy in the Pacific Northwest have operated under a congressional mandate to protect fish and wildlife in the Columbia River Basin. However, nearly half a century later, the number of wild salmon and steelhead returning to their native spawning grounds is still in decline, largely due to dam operations in the Columbia and its tributaries. This Note examines the history of hydroelectric power generation in the Columbia River Basin and its impact on fish populations, drawing parallels between the environmental crisis in the Columbia River …

Dendrimer Nanogels With Built-In Free Radical Scavenging Enable Efficient Topical Delivery Of A Hydrophilic Antioxidant To Restore Lens Redox Balance For Cataract Treatment, Lin Qi, Huari Kou, Anna Chernatynskaya, Da Huang, Vimalin Jeyalatha Mani, Humeyra Karacal, Nuran Ercal, Hu Yang

Chemistry Faculty Research & Creative Works

Cataract is a leading cause of vision impairment worldwide and are primarily caused by oxidative stress that damages and aggregates lens proteins, leading to lens opacification. However, the eye's anatomical barriers limit the penetration and bioavailability of antioxidant therapies. To address this challenge, a dendrimer-based nanogel with a built-in reactive oxygen species (ROS)-scavenging capability developed by us was employed to deliver the antioxidant N-acetylcysteine (NAC) to the lens. NAC was loaded into a generation-5 PEGylated poly(amidoamine) dendrimer (G5-PEG-TK, termed the GPT) nanogel. The resulting NAC-GPT was characterized for its ROS-scavenging activity, bioavailability, and corneal permeability. The efficacy of NAC-GPT was …

Co-Ordination Driven Heteroleptic Self-Assembly Of Naphthalene Diimide And Aromatic Dicarboxylate, Rosanna Jees, Kennedy Kuchta, Joshua Do, Erendra Manandhar

Posters - 2026

Co-ordination driven self-assembly is a powerful tool to construct supramolecular co-ordination complexes (SCCs) with predictable and well-defined molecular structures. Fujita, Stang, Newkome, & others have developed novel methodology to synthesize 2D & 3D Metallo-supramolecular structures, such as triangles, cubes, and octahedrons. These have potential applications for optical materials, sensing, catalysis, light harvesting & emissions due to the structures’ well-defined cavity and easy functionalization at the periphery position of ligands.1–4 SCCs with various functional groups, fluorophores, and chromophores, like crown ethers, carbazoles, fullerenes, and dendrimers, have been reported through self-assembly, yet naphthalene-diimide (NDI)-based macrocycles and cages are limited. This project focuses …

Lego®-Based Cubesats For Space Outreach, Stefan Brandle, Joshua Brown, Evan Smith, Drew Nye, Sydney Reddy, Twidy Kwae, Kaiya Grzesiak, Matthew Roderer, John Hetz

Faculty-Led Student Projects in CSE

Taylor University Computer Science and Engineering, in collaboration with NearSpace Education, has initiated a multi-year effort to enhance space-awareness by offering K-12 students career-impacting opportunities to build and fly satellites that have a LEGO®-robotics-based payload. This effort is intended as an outreach in the spirit of the ThinSat project (2017-2021) supported by Virginia Space, Twiggs Space Lab, Orbital ATK, NearSpace Launch, and the NASA Wallops Flight Facility, among others. We hope to receive permission to name the satellite LEGO-SAT-0.

Evaluation Of Seal!Nd: School Year 2024-2025, Shawnda Schroeder, Rashid Ahmad

Indigenous Health Faculty Publications

Dr. Schroeder and Rashid worked with the team at the Oral Health Program to collect data on the clinical reach of the School-based Sealant program (SEAL!ND), the referral practices, dental sealant cost savings, and perceptions of school personnel regarding their experiences with the program. SEAL!ND continues to make a measurable difference in improving children’s oral health by increasing access to preventive care, reducing barriers for families, and supporting schools in meeting the needs of their students. The program’s impact is reflected not only in the thousands of services provided each year, but also in the strong satisfaction and gratitude expressed …

Next-Generation Democratic Cyber Statecraft - Balancing The Signal: Shutdown Shocks And Democratic Digital Governance, Scott M. Di Panni

School of Public Policy Capstones

This paper develops Next-Generation Democratic Cyber Statecraft (NG-DCS), a unified strategic doctrine for democratic governments to contest the cognitive domain against authoritarian adversaries. Drawing on twenty-six years of cross-national panel data (1999–2024) spanning 213 countries, game-theoretic modeling, and qualitative case analysis, the paper establishes three interconnected empirical and theoretical foundations. First, cross-national OLS regression across 160+ countries demonstrates that regime type is the dominant structural determinant of internet freedom (R²=0.615, β=2.513, p< 0.001), explaining more than twice the variance attributable to per-capita wealth (R²=0.268). Democratic governance, not economic development, produces open digital environments. Second, a two-way fixed effects (TWFE) difference-in-differences study exploiting government-ordered internet shutdowns as discrete policy interventions finds that digital restrictions causally degrade V-Dem governance quality by 0.21–0.38 standard deviations (p< 0.001 across all specifications). Treatment effects are immediate (β=−0.302 at k=0) and persist through five post-treatment years (β=−0.246 at k=+5), indicating structural rather than transitory governance damage. Parallel trends validation (p=0.352) and Callaway–Sant’Anna heterogeneity-robust estimation (ATT=−0.230, SE=0.077) support causal identification. Instrumental variable triangulation (2SLS β=−0.949, p=0.005) confirms that simultaneity was attenuating, not inflating, the primary estimates. Third, formal game-theoretic analysis reveals that the current U.S.–adversary equilibrium is (Restrain, Escalate)—the risk-dominant but Pareto-inferior outcome of a Stag Hunt structure. China, Russia, North Korea, and Venezuela each occupy structurally distinct positions (Stackelberg commitment, asymmetric two-level, autarky, and reactive trigger, respectively), requiring differentiated doctrinal responses rather than a uniform strategic playbook. Generative AI and algorithmic governance are shown to accelerate cognitive vulnerability by collapsing influence operation costs and exploiting engagement-optimized platform architectures that systematically degrade deliberative capacity in democratic populations.

Targeting Oncogenes: Development And Characterization Of Aurka And Her2 Inhibitors, Itzel Montoya

Chemistry Theses

Targeted inhibition of oncogenes has remained a key strategy in the development of more potent, effective, and less toxic therapeutic anticancer agents. Among the most clinically significant signaling pathways are those mediated by the Human Epidermal Growth Factor Receptor 2 (HER2) and Aurora Kinase A (AurKA). HER2 is a member of the ErbB receptor family that supports cell growth and proliferation through downstream signaling of the PI3K and MAPK pathways and is closely linked to more aggressive tumors and therapeutic resistance. AurKA is a protein kinase essential for mitotic spindle assembly, centrosome maturation, and other key processes in cell cycle …

Efficacy Analysis In Clinical Trials: A Comprehensive Review Of Statistical And Machine Learning Approaches, Dhrubajyoti Ghosh, Samhita Pal

Faculty Articles

Efficacy testing is a cornerstone of clinical trials, ensuring that medical interventions achieve their intended therapeutic effects. Over the decades, a wide range of statistical methodologies have been developed to address the complexities of clinical trial data, including parametric, nonparametric, Bayesian, and machine learning approaches. Parametric methods, such as t-tests, ANOVA, and LMMs, have traditionally been the foundation of efficacy testing due to their efficiency under well-defined assumptions. Nonparametric techniques, including the Friedman test, Brunner-Munzel test, and modern extensions like nparLD, have emerged as robust alternatives, particularly for skewed, ordinal, or non-normal data. Bayesian methodologies have enabled the incorporation of …

Testing The Intermediate Disturbance Hypothesis On Anthropogenic Pressure In Central Alabama, Gavin Terrell

Theses

Biodiversity is fundamental to maintaining ecosystem structure and function globally. Prior to the late 20th century, ecological theory generally predicted that biodiversity would be highest in systems experiencing minimal disturbance. However, Joseph H. Connell challenged this view with the Intermediate Disturbance Hypothesis (IDH), which posits that species diversity peaks at intermediate levels of disturbance and declines under conditions of both low and high disturbance. Although widely cited, the applicability of the IDH to natural systems remains debated, particularly in the context of anthropogenic disturbances and when diversity is measured beyond species richness alone.

This study evaluated the predictions of the …

Pushing High-Performance Private Inference Towards Resource-Constrained Edge Clients, Xiangrui Xu

Computer Science Theses & Dissertations

The widespread adoption of Machine Learning as a Service (MLaaS) has enabled resource constrained edge clients, such as mobile and IoT devices, to leverage powerful deep learning mod els hosted on the cloud. However, this paradigm introduces critical privacy challenges regarding the client’s sensitive input data and the server’s proprietary model parameters. While cryptographic techniques like Homomorphic Encryption (HE) and Multi-Party Computation (MPC) enable Private Inference (PI), existing frameworks impose prohibitive computational and communication overheads that render them impractical for edge deployment. This dissertation introduces three novel frameworks—SPOT, LUTless, and PrivShap—to systematically address the efficiency bottlenecks of PI in edge …

Learning Techniques In Prediction Of Functional Epigenomic Events, Mohammad Shiri

Computer Science Theses & Dissertations

Accurately predicting functional epigenomic events from DNA sequences is critical to understanding gene regulation and the functional impact of non-coding variants. Despite considerable progress, critical challenges hamper the effectiveness and efficiency of existing deep learning approaches. These challenges include negative transfer in multi-task learning (MTL), suboptimal network architectures, and pervasive label noise, particularly the positive-unlabeled problem arising from data sparsity in single-cell assays. This dissertation presents a cohesive framework of novel learning techniques to effectively address these challenges. First, a highly scalable task grouping framework is presented to mitigate negative transfer in deep MTL. This method clusters tasks based on …