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Analysis Of The Influence Of Anthropometric Dimensions Of Postural Ergonomics Using Multiple Linear Regression, Gashbeen Faisal Najmaddin, Edrees Muhammed Tahir Harki Sep 2026

Analysis Of The Influence Of Anthropometric Dimensions Of Postural Ergonomics Using Multiple Linear Regression, Gashbeen Faisal Najmaddin, Edrees Muhammed Tahir Harki

Al-Bahir

Ergonomics is the study of designing and arranging a workspace or product to optimize the “fit” between people and their work, ensuring safety, comfort, and efficiency. The scientific literature indicates that ergonomic perspectives on the workplace are connected to the anthropometrics of societies. This study primarily aims to create a model that integrates multiple predictive variables to estimate the target variable. Multiple linear regression analysis is used to identify how different anthropometric dimensions predict postural ergonomics during prolonged sitting. Based on the regression models’ results, the predicted can be calculated using user anthropometry and existing chair dimensions. Furthermore, the primary …


Evaluating Medical Student Geriatric Competency Using A 5ms-Based Assessment Tool, Lauren R. Hersh Md, Amy Cunningham Phd, Mph, Xiya Wu Md Sep 2026

Evaluating Medical Student Geriatric Competency Using A 5ms-Based Assessment Tool, Lauren R. Hersh Md, Amy Cunningham Phd, Mph, Xiya Wu Md

Cooper Rowan Medical Journal

INTRODUCTION

Driven by an aging Baby Boomer generation, the United States is navigating a demographic transformation with far-reaching implications that include increased demand for chronic disease management and long-term care as well as increased stress on both healthcare costs and infrastructure. Generating a workforce competent in the delivery of care to older patients with complex, multimorbid conditions is fundamental to addressing this shift. Recognizing that the development of primary and specialty care physicians skilled in geriatric care begins in medical school, the American Geriatric Society developed minimum competencies grounded in the Geriatric 5Ms (Mind, Mobility, Medication, Multicomplexity, and …


Association Between Nonsyndromic Congenital Heart Disease And Childhood Cancer In A Population-Based, Retrospective Cohort Of 11 Million Children, Jeremy M Schraw, Karin C Mims, Sara B Stephens, Sonja A Rasmussen, Emily J Mason, Tania A Desrosiers, Charles J Shumate, Wendy N Nembhard, Mahsa M Yazdy, Eirini Nestoridi, Amanda E Janitz, Jean Paul Tanner, Russell S Kirby, Jason L Salemi, Chad D Huff, Sharon E Plon, Shaine A Morris, Philip J Lupo Sep 2026

Association Between Nonsyndromic Congenital Heart Disease And Childhood Cancer In A Population-Based, Retrospective Cohort Of 11 Million Children, Jeremy M Schraw, Karin C Mims, Sara B Stephens, Sonja A Rasmussen, Emily J Mason, Tania A Desrosiers, Charles J Shumate, Wendy N Nembhard, Mahsa M Yazdy, Eirini Nestoridi, Amanda E Janitz, Jean Paul Tanner, Russell S Kirby, Jason L Salemi, Chad D Huff, Sharon E Plon, Shaine A Morris, Philip J Lupo

Faculty, Staff and Students Publications

Background: Epidemiologic studies have demonstrated associations between congenital heart disease (CHD) and childhood cancer. However, these assessments have not fully accounted for the pathogenetic and clinical heterogeneity of CHD, limiting their capacity to inform pathogenetic studies and the clinical management of children with CHD.

Methods: To achieve a more detailed understanding of cancer risk in children with nonsyndromic CHD, we evaluated 60 cardiac lesions in 7 categories in a cohort of 11 million children from Massachusetts, North Carolina, Oklahoma, and Texas. We used Cox proportional hazards regression to estimate the hazard ratios (HRs) and 95% CIs of cancer in children …


Evaluating The Readability Of Online Patient Education Materials For Avascular Necrosis, Gabriella B. Smith, Grady H. Hofmann, Anna V. Gussner, Nicole S. Pham, Nneoma O. Duru, Kevin G. Shea Sep 2026

Evaluating The Readability Of Online Patient Education Materials For Avascular Necrosis, Gabriella B. Smith, Grady H. Hofmann, Anna V. Gussner, Nicole S. Pham, Nneoma O. Duru, Kevin G. Shea

Journal of Patient-Centered Research and Reviews

Purpose: Avascular necrosis (AVN) is a progressive pathology affecting pediatric and adult patients. Given the risks of joint collapse and surgery, patients frequently research their condition online. The average reading level in the United States is approximately the eighth-grade level. The National Institutes of Health (NIH) recommend that patient materials be written at or below a sixth-grade level. This study aimed to assess the readability and quality of online AVN resources.

Methods: A Google search using the terms “avascular necrosis” and “osteonecrosis” was conducted, and firstpage results were aggregated. Flesch-Kincaid Grade Level, Gunning Fog Index, and Flesch Reading Ease tests …


Under Pressure And Underrecognized: The Role Of Social Workers And Case Managers In Screening For Social Determinants Of Health In The United States, Melissa L. Habrat, Lindsay D. Nelson, David A. Nelson Sep 2026

Under Pressure And Underrecognized: The Role Of Social Workers And Case Managers In Screening For Social Determinants Of Health In The United States, Melissa L. Habrat, Lindsay D. Nelson, David A. Nelson

Journal of Patient-Centered Research and Reviews

Social determinants of health (SDOH) screening is increasingly embedded in clinical care, yet the work of asking, documenting, and responding to social needs often falls to social workers and nurses or professional case managers who operate under significant time, staffing, and system constraints. We conducted a narrative review to examine how SDOH influence outcomes, identify systemic and emotional barriers to effective screening, and synthesize evidence-informed strategies that support implementation. Across included sources, findings clustered into three domains: challenges in integrating screening (policy and accreditation pressure, staffing and resource constraints, EHR documentation and interoperability limits, closed-loop referral and cross-sector partnership gaps, …


Copper Nanoparticles And Their Future In Drug Delivery And Anticancer Therapy, Keykavous Parang, Rajesh Vadlapatla, Cassia Charles, Kimberly Tang, Trang Nguyen, Amir Nasrolahi Shirazi, Ajoy Koomer Sep 2026

Copper Nanoparticles And Their Future In Drug Delivery And Anticancer Therapy, Keykavous Parang, Rajesh Vadlapatla, Cassia Charles, Kimberly Tang, Trang Nguyen, Amir Nasrolahi Shirazi, Ajoy Koomer

Pharmacy Faculty Articles and Research

Copper nanoparticles (CuNPs) have attracted growing attention in nanomedicine owing to their distinctive physicochemical, optical, and biological properties. Their large surface area, tunable size, ease of surface modification, and low cost make them attractive candidates for drug delivery, where they can both improve delivery efficiency and enable stimuli-responsive release. CuNPs also possess intrinsic antimicrobial, anticancer, anti-inflammatory, and photothermal activities, further broadening their biomedical utility. In this review, we synthesize recent advances in the synthesis, characterization, surface functionalization, and biomedical application of CuNPs, comparing chemical, physical, and green synthetic routes and their effects on stability, biocompatibility, and therapeutic efficacy. We examine …


Abstracts From The 2026 Health Care Systems Research Network (Hcsrn) Annual Conference, Dallas, Texas, Health Care Systems Research Network Sep 2026

Abstracts From The 2026 Health Care Systems Research Network (Hcsrn) Annual Conference, Dallas, Texas, Health Care Systems Research Network

Journal of Patient-Centered Research and Reviews

The Health Care Systems Research Network (HCSRN) comprises 18 learning health systems with integrated care delivery and embedded research units. The network’s annual conference serves as a forum for research teams from member institutions to disseminate project findings, explore scientific collaborations, and share insights about population-based research practices that can measurably improve health and health care for all. The theme of this year’s conference was “Scaling Learning Health Systems: Data-Driven Pathways to Better Outcomes.” Abstracts presented at HCSRN 2026 are published in this issue supplement of the Journal of Patient-Centered Research and Reviews, the journal of record for HCSRN’s annual …


Tarsal Tunnel Syndrome Due To Post-Traumatic Osseous Tunnel Formation: A Rare Case And Surgical Management, Dev Y. Patel, Eshan Doshi, Fiona Zimmerman, Jamal Revolus, Michael Kimball, Michael Franco Sep 2026

Tarsal Tunnel Syndrome Due To Post-Traumatic Osseous Tunnel Formation: A Rare Case And Surgical Management, Dev Y. Patel, Eshan Doshi, Fiona Zimmerman, Jamal Revolus, Michael Kimball, Michael Franco

Cooper Rowan Medical Journal

Tarsal tunnel syndrome (TTS) is classically a compressive neuropathy of the posterior tibial nerve beneath the flexor retinaculum, presenting with plantar foot pain and paresthesias. Standard surgical management of TTS involves release of the flexor retinaculum to decompress the nerve. We report a rare and unusual case of TTS in which the posterior tibial nerve was encased within a post-traumatic osseous tunnel accompanied by dense fibrotic tissue, representing an atypical and previously undescribed etiology of nerve entrapment. In this case, surgical decompression required a modified approach involving meticulous dissection of the tibial nerve from its encasement by heterotopic ossification and …


The Implementation Of Sel-Based Interactive E-Modules To Enhance Mental Health Literacy, Muhammad Arif Budiman Sucipto, Mulyani Mulyani Sep 2026

The Implementation Of Sel-Based Interactive E-Modules To Enhance Mental Health Literacy, Muhammad Arif Budiman Sucipto, Mulyani Mulyani

Jurnal Kajian Bimbingan dan Konseling

The mental health crisis among Generation Alpha students is concerning, marked by stagnating life purpose and digital academic pressure. This study aims to examine the effectiveness of an interactive SEL-based E-Module in enhancing students' mental health literacy, offering an innovative solution responsive to the digital era. Employing a Classroom Action Research design integrated with ADDIE. Thirty-two tenth-grade students with low initial literacy scores (mean pre-test = 42.3) participated through purposive sampling. The two-cycle intervention utilized a digital module featuring Private Mode (encrypted emotional journal) and Emergency Button (direct link to counselors). Data were collected through literacy scales, observations, interviews, and …


Dinamika Spasial Dengue Di Provinsi Sulawesi Selatan: Fragmentasi Spasial Tanpa Hotspot Persisten, Nurul Muthiah Salahuddin, Trisari Anggondowati, Syifa Nurhakiki Sep 2026

Dinamika Spasial Dengue Di Provinsi Sulawesi Selatan: Fragmentasi Spasial Tanpa Hotspot Persisten, Nurul Muthiah Salahuddin, Trisari Anggondowati, Syifa Nurhakiki

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Demam berdarah dengue (DBD) masih menjadi masalah utama kesehatan masyarakat di Sulawesi Selatan, dengan pola penularan yang bervariasi secara spasial maupun temporal. Pada tahun 2024, provinsi ini mencatat insidens DBD sebesar 66,04 per 100.000 penduduk, di mana hanya 12,5% kabupaten/kota yang mencapai target nasional (≤10 per 100.000). Belum diketahui pola spasial yang membentuk klaster yang persisten atau berubah antar waktu, sehingga dilakukan penelitian ini untuk menganalisis pola spasiotemporal serta persistensi klaster spasial kejadian DBD di Sulawesi Selatan. Penelitian ini merupakan studi ekologi dengan pendekatan repeated cross-sectional menggunakan data surveilans DBD tingkat kabupaten/kota periode 2021–2024 yang mencakup 24 kabupaten/kota. Analisis meliputi …


An Introduction To The History Of Medicine In Medical Education, Mary E. Horton Mph, Ma, Phd Sep 2026

An Introduction To The History Of Medicine In Medical Education, Mary E. Horton Mph, Ma, Phd

History of Medicine Seminar

No abstract provided.


Plasma Vgf As A Predictive Biomarker For Early Acute Kidney Injury In Critically Ill Elderly Patients: A Combined Clinical And Mendelian Randomization Study, Xianyang Guo, Yu Hao, Rujie Chenn, Benji Wang, Shengwei Jin Sep 2026

Plasma Vgf As A Predictive Biomarker For Early Acute Kidney Injury In Critically Ill Elderly Patients: A Combined Clinical And Mendelian Randomization Study, Xianyang Guo, Yu Hao, Rujie Chenn, Benji Wang, Shengwei Jin

Saudi Medical Journal

Objectives: To assess whether VGF nerve growth factor inducible (VGF) can serve as a reliable predictor of acute kidney injury (AKI) among patients requiring intensive care.
Methods: We first conducted a Mendelian randomization (MR) analysis to explore the potential causal link between plasma VGF levels and AKI risk. Subsequently, 128 critically ill individuals admitted to our intensive care unit were prospectively enrolled. Within 24 hours of either hospital admission or clinical decline, both blood and urine specimens were obtained. We measured VGF concentrations in plasma and urine, along with plasma cystatin C (pCysC), plasma and urinary neutrophil gelatinase-associated lipocalin (NGAL), …


Knowledge, Practice And Perceived Barriers Of Healthcare Provider Adherence To The Notifiable Disease Surveillance System (Ndss) In Government Hospitals And Primary Healthcare Centers In Jazan, Saudi Arabia: A Cross-Sectional Study, Moatasem F. Hakmi, Alaa Mathkour, Yousef Zahrani, Rayan I. Binduhayyim, Saad S. Alqahtani, Muhammad Z. Iqbal Sep 2026

Knowledge, Practice And Perceived Barriers Of Healthcare Provider Adherence To The Notifiable Disease Surveillance System (Ndss) In Government Hospitals And Primary Healthcare Centers In Jazan, Saudi Arabia: A Cross-Sectional Study, Moatasem F. Hakmi, Alaa Mathkour, Yousef Zahrani, Rayan I. Binduhayyim, Saad S. Alqahtani, Muhammad Z. Iqbal

Saudi Medical Journal

Objective: To assess and compare healthcare providers' understanding of the Notifiable Disease Surveillance System (NDSS), alongside reported and perceived challenges, across public hospitals and primary healthcare centers in Jazan, Kingdom of Saudi Arabia.
Methods: A cross-sectional study was conducted between 10 January 2025 and 30 December 2025 among health care providers at Jazan hospitals and primary healthcare centers (PHCs) (n = 420). Data were collected via structured self-administered questionnaire that included the following sections: demographic data, knowledge of the NDSS, reporting practices, competency of the Health Electronic Surveillance Network (HESN) and perceived barriers. Descriptive and inferential statistics were used to …


Cranial Mri In Girls With Central Precocious Puberty: Clinical Characteristics And Predictors Of Abnormal Findings, Fahad N. Al Juraibah, Mashael M. Alharbi, Reem D. Alharbi, Joud S. Albaraki, Sarah S. Aldharman, Hala A. Alghamdi, Nagarajkumar Yenugadhati, Abdullah I. Alhammad, Angham N. Almutair, Ibrahim A. Al Alwan Sep 2026

Cranial Mri In Girls With Central Precocious Puberty: Clinical Characteristics And Predictors Of Abnormal Findings, Fahad N. Al Juraibah, Mashael M. Alharbi, Reem D. Alharbi, Joud S. Albaraki, Sarah S. Aldharman, Hala A. Alghamdi, Nagarajkumar Yenugadhati, Abdullah I. Alhammad, Angham N. Almutair, Ibrahim A. Al Alwan

Saudi Medical Journal

Objectives: To describe the clinical profile of girls with central precocious puberty (CPP) and determine the factors associated with abnormal cranial magnetic resonance imaging (MRI) findings.
Methods: This retrospective study included girls aged 8 years or younger with a diagnosis of CPP who received care at King Abdullah Specialized Children's Hospital in Riyadh, Kingdom of Saudi Arabia, between 2015 and 2023. Data on clinical presentation, biochemical results, imaging findings, and treatment were obtained from medical records. Logistic regression analysis was performed to determine variables associated with MRI utilization and the occurrence of abnormal MRI findings.
Results: The cohort comprised 70 …


Thrombosis Rate And Risk Factors In Pediatric Patients With Peripherally Inserted Central Catheters, Ahmed A. Alabdulkarim, Abdullah I. Almojali, Tharaa S. Alhowaish, Dena S. Alsuhaibani, Norah I. Alshafi, Amin I. Alzahrani, Mohammed O. Alotaibi, Yousef A. Alghamdi, Hamad A. Alkhalaf Sep 2026

Thrombosis Rate And Risk Factors In Pediatric Patients With Peripherally Inserted Central Catheters, Ahmed A. Alabdulkarim, Abdullah I. Almojali, Tharaa S. Alhowaish, Dena S. Alsuhaibani, Norah I. Alshafi, Amin I. Alzahrani, Mohammed O. Alotaibi, Yousef A. Alghamdi, Hamad A. Alkhalaf

Saudi Medical Journal

Objective: To determine symptomatic thrombosis incidence in pediatric patients with peripherally inserted central catheters (PICCs) and identify associated patient and procedure-related risk factors in a tertiary pediatric center in Saudi Arabia.
Methods: We conducted a retrospective cohort study at King Abdullah Specialized Children's Hospital, Riyadh, Kingdom of Saudi Arabia, including patients aged 0–14 years who underwent PICC insertion in the Interventional Radiology department between January 2019 and June 2023. Data on demographics, comorbidities, procedural details, and outcomes were extracted from the electronic medical record system (BestCare). Symptomatic thrombosis was defined as Doppler-confirmed thrombosis with clinical signs. Associations were tested using …


Advancing Impact: A National Approach To Knowledge Translation In Saudi Arabia-The Saudi National Institute Of Health Experience, Maha M. Aleid, Manar A. Alharbi, Amal N. Almadouj, Ahmad I. Alrawaji, Lamia A. Alhaqbani, Fars K. Alanazi Sep 2026

Advancing Impact: A National Approach To Knowledge Translation In Saudi Arabia-The Saudi National Institute Of Health Experience, Maha M. Aleid, Manar A. Alharbi, Amal N. Almadouj, Ahmad I. Alrawaji, Lamia A. Alhaqbani, Fars K. Alanazi

Saudi Medical Journal

Objectives: To present a reproducible national model for translating research findings into evidence-based clinical practice guidelines.
Methods: The Saudi National Institute of Health launched the initiative titled ``Transforming the Outcomes of Published Health Research into Medical Guidelines that Enhance Medical Practices to Improve the Quality of Human Health'' on February 3, 2025. The initiative aimed to identify and assess research outcomes published between January 1, 2020, and December 31, 2024 across 6 predefined thematic tracks relevant to the Saudi population. Eligible publications were collected within one month after the submission portal opened. Following closure of portal, all submissions were evaluated …


Estimating Radiation Dose And Proposing Institutional Diagnostic Reference Levels For Paediatric Fluoroscopy Of Micturating Cystourethrogram: Age- And Weight - Specific Comparisons, Khalid M. Aloufi Sep 2026

Estimating Radiation Dose And Proposing Institutional Diagnostic Reference Levels For Paediatric Fluoroscopy Of Micturating Cystourethrogram: Age- And Weight - Specific Comparisons, Khalid M. Aloufi

Saudi Medical Journal

Objective: To compare age- and weight-specific methods used to estimate radiation doses and to propose institutional diagnostic reference levels (DRLs) for paediatric fluoroscopy of micturating cystourethrogram (MCUG).
Methods: In this retrospective study, MCUG fluoroscopy parameters were gathered for 100 paediatric patients from July 2025 to January 2026. The data included the MCUG paediatric procedures for patients aged 0–15 years. The data were categorized into paediatric weight- and age-specific groups. Paediatric weight-specific groups were ≤ 5, 5 < – 10, 10 < – 20, and >20 kg, and paediatric age-specific groups were ≤ 1, 1 < – 5, 5 < – 10, and < 10 – 15 years old.
Results: Differences were observed in dose area product (DAP) and DRL results for age- …


Potential Drug–Drug Interactions In Patients Undergoing Hemodialysis: A Retrospective Observational Study, Buthainah B. Al-Ammash, Fawaz A. Alharbi, Omar D. Al-Hejaili, Mansour A. Mahmoud, Mazin A. A. Abdelaziz, Alaa I. Alrais, Shahad A. Albakri, Ibrahim F. Alharbi, Sara A. Felemban, Abdullah H. Almatrafi, Salman A. Alabdali, Yaser M. Alahmadi Sep 2026

Potential Drug–Drug Interactions In Patients Undergoing Hemodialysis: A Retrospective Observational Study, Buthainah B. Al-Ammash, Fawaz A. Alharbi, Omar D. Al-Hejaili, Mansour A. Mahmoud, Mazin A. A. Abdelaziz, Alaa I. Alrais, Shahad A. Albakri, Ibrahim F. Alharbi, Sara A. Felemban, Abdullah H. Almatrafi, Salman A. Alabdali, Yaser M. Alahmadi

Saudi Medical Journal

Objectives: To evaluate the prevalence, characteristics, and determinants of potential drug–drug interactions (pDDIs) among patients with end-stage renal disease (ESRD) undergoing hemodialysis (HD) at a tertiary care hospital in Al-Madinah Al-Monawara, Kingdom of Saudi Arabia.
Methods: Data for this retrospective observational study were extracted from the electronic medical records of adult patients (≥ 18 years) diagnosed with ESRD and receiving hemodialysis (HD) between October 2022 and March 2023. The pDDIs were identified and classified using Lexicomp® (Wolters Kluwer, Alphen aan den Rijn, Netherlands). Descriptive statistics summarized patient characteristics and pDDIs, and univariate logistic regression was implemented to investigate the determinants …


Drooling In Children With Cerebral Palsy: A Narrative Review Of The Current Management Landscape, Kamel A. Alenazi Sep 2026

Drooling In Children With Cerebral Palsy: A Narrative Review Of The Current Management Landscape, Kamel A. Alenazi

Saudi Medical Journal

Children with developmental or neurological disorders, such as cerebral palsy, present with impaired motor function, resulting in impaired swallowing, feeding, and drooling. The prevalence of chronic drooling radically changes from 0.5% in children >4 years to 60% in children with neurological ailments. Drooling can have a serious impact on the quality of life of affected children, which can create a sense of isolation and refusal by peers. In addition, drooling results in not only financial but also considerable emotional turmoil for caregivers of affected children, who are frequently confronted with difficulty managing the underlying neurological impairment of their child. In …


Scoping Review Of Mental Health Outcomes Of Cosmetic Procedures Among The Saudi Population, Hessah Alzahrani Sep 2026

Scoping Review Of Mental Health Outcomes Of Cosmetic Procedures Among The Saudi Population, Hessah Alzahrani

Saudi Medical Journal

Objective: To comprehensively examine the mental health outcomes associated with cosmetic procedures among the Saudi population, with a particular focus on psychological well-being, self-esteem, anxiety, body image, and quality of life.
Methods: This scoping review was conducted in accordance with the Joanna Briggs Institute (JBI) methodology and reported following the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews guidelines. A structured search was performed across international databases, including PubMed, PsycINFO, Scopus, Web of Science, and Google Scholar, in addition to national Arabic databases. Studies investigating the psychological outcomes of both surgical (rhinoplasty and body contouring) and …


Quality, Patient Experience, And Service Gaps In Home Healthcare In Saudi Arabia: A Systematic Review Aligned With Vision 2030, Eman Alawad, Rasha M. Mahrous, Lubna A. Elshaib Sep 2026

Quality, Patient Experience, And Service Gaps In Home Healthcare In Saudi Arabia: A Systematic Review Aligned With Vision 2030, Eman Alawad, Rasha M. Mahrous, Lubna A. Elshaib

Saudi Medical Journal

Objectives: To assess the quality of home healthcare (HHC) services, patient experience, and existing service gaps in Kingdom of Saudi Arabia.
Methods: This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) statement. PubMed, MEDLINE, Scopus, Web of Science, CINAHL, and Google Scholar were searched for studies published between January 2011 and January 2025. Eligible studies included observational, qualitative, mixed-methods, and interventional studies conducted in Saudi Arabia that examined home healthcare quality, patient or caregiver experience, or service delivery gaps. Two reviewers independently screened studies, extracted data, and assessed methodological quality …


Implementing Diagnosis-Related Groups For Value-Based Healthcare In Saudi Arabia: A Systematic Review Of Evidence On Barriers And Facilitators, Racha M. Naim, Michelle A. Badore, Justin J. Needle Sep 2026

Implementing Diagnosis-Related Groups For Value-Based Healthcare In Saudi Arabia: A Systematic Review Of Evidence On Barriers And Facilitators, Racha M. Naim, Michelle A. Badore, Justin J. Needle

Saudi Medical Journal

Objective: To examine the barriers and facilitators to implementing Diagnosis-related groups (DRGs) in Kingdom of Saudi Arabia, aiming to identify actionable insights for policymakers and stakeholders to advance value-based healthcare (VBHC) adoption effectively.
Methods: A systematic search of bibliographic databases and relevant grey literature was conducted. Data were synthesized using the Consolidated Framework for Implementation Research (CFIR) to categorize barriers and facilitators across 5 domains.
Results: A total of 10 studies met the eligibility criteria. Key facilitators included the adoption of patient classification systems, standardized data sets, government policy support, and the availability of advanced health information systems. Barriers included …


From Bench To Bedside: Evolving Definitions Of Translational Research, Hana A. Alhumud, Fars K. Alanazi, Edward B. Devol Sep 2026

From Bench To Bedside: Evolving Definitions Of Translational Research, Hana A. Alhumud, Fars K. Alanazi, Edward B. Devol

Saudi Medical Journal

Objective: To synthesize current evidence on the evolution, frameworks, and methodological approaches used to define and operationalize translational research, which serves as a bridge between scientific discovery and its application in clinical medicine, public health, and policy.
Methods: We systematically searched PubMed, Scopus, and Web of Science for peer-reviewed studies published up to 2023. Search terms combined translational research–related keywords (such as ``bench-to-bedside,'' ``implementation science,'' ``precision medicine'') and relevant MeSH terms. Eligible studies focused on conceptual models, frameworks, or methodological approaches related to translational research and were published in English. After duplicate removal and PRISMA-guided screening, 33 publications were included. …


Mentorship As A Catalyst For Change Readiness: A Qualitative Study Of How Effective Mentoring Mitigates Burnout And Turnover During Organizational Transformation, Jeffery M. Camp Sep 2026

Mentorship As A Catalyst For Change Readiness: A Qualitative Study Of How Effective Mentoring Mitigates Burnout And Turnover During Organizational Transformation, Jeffery M. Camp

Journal of Online Mentoring

This qualitative study examined how effective mentorship mitigates burnout and attenuates turnover intention during organizational change, foregrounding the perspectives of experienced mentors. Drawing on Biggs’s presage–process–product (PPP) model, data were collected through semi-structured interviews (n = 12) and two focus group discussions (n = 6 each), engaging 18 unique mentors employed in organizations with 1,000 or more employees. Thematic analysis following Braun and Clarke’s six-phase protocol yielded four themes: (1) mentorship as strategic facilitation of organizational change; (2) mentorship as provision of emotional and psychological support; (3) empowering mentees through relationship-building; and (4) applying adaptive and reflective strategies. …


“I Was Not Wonder Woman And Required Help”: Black, Latina, And White Women’S Recovery From The Covid-19 Pandemic, J. Mitchell Vaterlaus, Colton Pierce, Harry Foster, Alison Brennan, Nicole Wanago Sep 2026

“I Was Not Wonder Woman And Required Help”: Black, Latina, And White Women’S Recovery From The Covid-19 Pandemic, J. Mitchell Vaterlaus, Colton Pierce, Harry Foster, Alison Brennan, Nicole Wanago

Journal of Social, Behavioral, and Health Sciences

The COVID-19 pandemic disproportionately affected women, particularly women of color, yet less is known about their recovery experiences following the end of the public health emergency. This exploratory mixed-methods study examined recovery from the COVID-19 pandemic among Black, Latina, and White women in the United States. Participants (N = 133) completed a survey that included a self-reported recovery measure and open-ended questions regarding their recovery experiences. A chi-square analysis indicated a significant association between race/ethnicity and recovery status, with Latina women more likely to report ongoing recovery than Black and White women. Codebook thematic analysis identified four themes: (1) …


Discovery Of Ro 41-0960, A Non-Steroidal Inhibitor Of The Na+/K+-Atpase, Carlos Cruz-Cortés, Jaroslava Šeflová, Guadalupe Guerrero-Serna, Eric N. Jimenez-Vazquez Sep 2026

Discovery Of Ro 41-0960, A Non-Steroidal Inhibitor Of The Na+/K+-Atpase, Carlos Cruz-Cortés, Jaroslava Šeflová, Guadalupe Guerrero-Serna, Eric N. Jimenez-Vazquez

Health & Biomedical Sciences Faculty Publications

The Na+/K+-ATPase (NKA) is a central regulator of cardiac ion homeostasis and a validated target for heart failure. Yet, cardiotonic steroids used in clinical practice are limited by a narrow therapeutic window and pro-arrhythmic effects. Here, we identify Ro 41-0960 as a non-steroidal inhibitor of NKA with a distinct mechanistic profile. The compound inhibits NKA activity with IC50 values of 17.9 ± 1.1 µM for purified enzyme and https://doi.org/10.3 ± 1.1 µM in microsomal preparations. ATP-dependent activity measurements revealed a non-monotonic response in which inhibition was most pronounced at ATP concentrations below 4 mM and diminished …


Intouch Week Of September 14, 2026, New York Medical College Sep 2026

Congenital Nephrotic Syndrome In Oman: A 20-Year Single-Centre Experience, Muzna Al Hashmi, Anisa Al Maskari, Sulaiman Al Saidi, Badria Al Ghaithi, Mohammed Al Riyami, Naifain Al Kalbani Sep 2026

Congenital Nephrotic Syndrome In Oman: A 20-Year Single-Centre Experience, Muzna Al Hashmi, Anisa Al Maskari, Sulaiman Al Saidi, Badria Al Ghaithi, Mohammed Al Riyami, Naifain Al Kalbani

Sultan Qaboos University Medical Journal

Objectives: Congenital nephrotic syndrome (CNS) is a rare, severe disease presenting within the first three months of life, with limited prevalence data from Oman and the Gulf region. This study aimed to report 20 years' experience of congenital nephrotic syndrome (CNS) in a single centre in Oman. Methods: This retrospective study including children diagnosed with nephrotic syndrome in first 3 months of life, from January 2000 to December 2020 at Royal Hospital, Muscat, Oman. Results: A total of 26 patients were included in the study, with no gender predominance. Consanguinity was noted in 61.5% of patients and a …


The Mv Hondius Hantavirus Outbreak: Implications For Clinical Vigilance And Regional Health Security In The Gcc Countries, Seif Salem Al Abri, Ahmed S Al-Mandhari, Ziad A Memish Sep 2026

The Mv Hondius Hantavirus Outbreak: Implications For Clinical Vigilance And Regional Health Security In The Gcc Countries, Seif Salem Al Abri, Ahmed S Al-Mandhari, Ziad A Memish

Sultan Qaboos University Medical Journal

No abstract provided.


Advancing Blood Production And Distribution: Leveraging Ai In The Expeditionary Care Environment, Andrew Hall, Michael Carrillo, Garrion Jackson, Jennifer Hall, Ryan Comes Sep 2026

Advancing Blood Production And Distribution: Leveraging Ai In The Expeditionary Care Environment, Andrew Hall, Michael Carrillo, Garrion Jackson, Jennifer Hall, Ryan Comes

Joint Force Quarterly

It is a whole of government effort to ensure there is sufficient blood supply during times of crisis and conflict. The interagency is responsible for the blood production, delivery and ultimately utilizes blood across the world to treat hemorrhaging patients. Blood is an individually donated resource that saves lives in the expeditionary environment. The ideal blood supply chain maximizes production, utilization, and remaining shelf life of blood products where it is needed across the world. Optimized production and delivery of blood maximizes lifesaving while minimizing wastage. The advancement in artificial intelligence represents an opportunity to apply technology to this critical …