Digital Commons Network^™

Rust Diseases Of Apple, John R. Hartman

Agriculture and Natural Resources Publications

Three related rust diseases occur on apple trees in Kentucky: cedar-apple rust, cedar-hawthorn rust, and cedarquince rust. Crabapple, hawthorn, mountain ash, pear, and serviceberry are also susceptible to these diseases. All three rusts are caused by different species of the fungus Gymnosporangium, each of which must spend a phase of its life cycle as a parasite on Juniperus species such as native red cedars or ornamental junipers.

Although cedar rusts can cause unsightly growths on Juniperus, they do not usually cause serious damage to these plants. Rust diseases can cause serious losses on apples, however, as a result …

Metal-Resistance Genetically Engineered Bacteria, Sylvia Daunert, Donna Scott, Sridhar Ramanathan

KWRRI Research Reports

Bacterial-based electrochemical and optical sensing systems that respond in a highly selective and sensitive manner to antimonite and arsenite have been developed. This was accomplished by using genetically engineered bacteria bearing one of two plasmids constructed for our studies. The first plasmid, pBGD23, contains the operator/promoter region (O/P) and the gene of the ArsR protein from the ars operon upstream from the β-galactosidase gene. In the absence of antimonite/arsenite, ArsR binds to the 0/P site and prevents the transcription of the genes for ArsR and β-galactosidase, thus blocking expression of these proteins. When antimonite or arsenite is present in the …

Negotiating The Healthy Self: A Theory Of Health Behavior In Older Adults, Barbara Schwitz White

Loma Linda University Electronic Theses, Dissertations & Projects

Researchers have identified discrete behaviors of older persons to maintain or improve health and prevent or treat illness. Few have developed theories of health behavior specific to this population. The purpose of this study was to develop a substantive theory to explain how health and illness are integrated into and influence behaviors in the daily lives of community-residing older persons. Using grounded theory design and analysis, 26 participant observations involving 186 individual encounters, and seven semistructured [sic] one-on-one interviews were conducted at two senior centers in urban southern California, between 1992 and 1994.

Informants defined health in terms of physiologic …

Periodontal Repair In Dogs : Effect Of Recombinant Human Transforming Growth Factor Beta-1 On Guided Tissue Regeneration, Saghi Shayan Razi

Loma Linda University Electronic Theses, Dissertations & Projects

The objective of this study was to evaluate bone and cementum regeneration in the critical size, supraalveolar, periodontal defect model following surgical implantation of recombinant human transforming growth factor beta-1 (rhTGFß-1) in conjunction with guided tissue regeneration (GTR). Five male beagle dogs were used in a split-mouth design. Alternate jaw quadrants in consecutive animals received GTR with rhTGFß-1 in a resorbable calcium carbonate carrier. Contralateral jaw quadrants received GTR with carrier only (control). The healing interval was 4 weeks. Clinical healing was generally uneventful, however, minor membrane exposures were observed for both treatments with limited gingival inflammation. All defects with …

Bone Morphogenetic Proteins And Periodontal Repair, Michael B. Lee

Loma Linda University Electronic Theses, Dissertations & Projects

For over thirty years now, research has been carried out to isolate and purify bone morphogenetic protein (BMP), a substance which has been shown to induce heterotopic bone formation in various animal species. Recent advances in the fields of developmental biology, molecular biology and genetics, have shown that the BMPs not only are responsible for postfetal bone induction (including normal bone remodeling, healing and repair), but are also critical during embryogenesis - not only in regards to the skeletal system, but quite possibly in the morphogenesis and pattern formation of other tissues and organs as well.

Due to their bone …

The Effects Of Lowering Cholesterol On Vasodilation, Maria Christi Hardt

Loma Linda University Electronic Theses, Dissertations & Projects

Endothelial dysfunction has been found prior to any signs of atherosclerotic plaque formation in patients with a variety of risk factors for atherosclerosis. Elevated serum cholesterol has repeatedly been associated with endothelial dysfunction as demonstrated by impaired vasoreactivity to vasodilating stimuli.

The aim of this research was to determine whether short term lowering of serum cholesterol levels by life style changes or by cholesterol lowering medication could reverse or reduce the endothelial dysfunction. The brachial artery diameter was measured by high-resolution ultrasound at rest and during reactive hyperemia pre and postintervention. Fifty-three subjects with cholesterol levels above 240 mg/dl were …

Treatment Effects Of The Edgewise Bioprogressive Herbst Appliance, Bernard C. Chang

Loma Linda University Electronic Theses, Dissertations & Projects

The effect of the Edgewise Bioprogressive Herbst appliance, as described by Dr. Terry Dischinger, was investigated on 24 Class II, Division 1 malocclusions. Mean pretreatment age of this sample was 11.2 months. All patients were treated by Dischinger with a Bioprogressive Herbst appliance. Lateral cephalographs taken before, after Herbst appliance therapy, and after edgewise treatment were traced, then digitized into Quick Ceph™. Measurements were computed by the computer software. The following results were found: 1) Average treatment time was 9 months. 2) An overcorrected Class I relationship was achieved. 3) Class II malocclusion was corrected by 4.5 mm skeletal alteration …

Social Issues Of Genome Innovation And Intellectual Property, Elaine Alma Draper

RISK: Health, Safety & Environment (1990-2002)

Dr. Draper's focus is the use of personal information derived from genome research. She identifies several potential problems, including access to and control of genetic information, employment discrimination and social stratification. She also recommends possible solutions.

The Latency-Related Gene Of Bovine Herpesvirus 1 Encodes A Product Which Inhibits Cell Cycle Progression, L. M. Schang, Ashfaque Hossain, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

Bovine herpesvirus 1 (BHV-1) establishes a latent infection in the sensory ganglionic neurons of cattle. The exclusive viral RNA expressed in a latent infection is the latency-related (LR) RNA, suggesting that it regulates some aspect of a latent infection. During the course of a productive infection, alphaherpesviruses induce certain events which occur during cell cycle progression. Consequently, we hypothesized that a BHV-1 infection might induce events in neurons which occur during cell cycle progression. In agreement with this hypothesis, cyclin A was detected in neurons of trigeminal ganglia when rabbits were infected. Neuronal cell cycle progression or inappropriate expression of …

Mutagenecity Of Formocresol, Glutaraldehyde, Ferric Sulfate And Aluminum Chloride : Materials Used In Therapeutic Pulpotomies, Adolfo Barrera

Loma Linda University Electronic Theses, Dissertations & Projects

Ferric sulfate (Astringedent) and aluminum chloride (Hemodent) have been proposed as possible medicaments for use in primary teeth for therapeutic pulpotomies.

There is little information in the literature about the biologic properties of these medicaments.

The purpose of this study was to evaluate the mutagenic response of the ferric sulfate and aluminum chloride and compare them with glutaraldehyde (1.5%, 1% and 0.5% concentration) and formocresol (2%, 0.75%, 0.01% and 0.005% concentration). TA98 and TA1535 strain were used in the Ames test to assess mutagenecity. Neither ferric sulfate nor aluminum chloride exhibited mutagenic potential, in comparison with glutaraldehyde and formocresol, which …

Louisiana State University Medical Center - 1996 - Spring Commencement, Office Of The Registrar, Lsu Health Sciences Center-No

Graduation & Commencement Programs

The program for the 1996 Spring Commencement of LSU Health Sciences Center - New Orleans held May 18, 1996.

1996 - The First Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the First Annual Symposium of Student Scholars, held on May 10th, 1996. Includes abstracts from presentations.

A Correlative Study Of An At-Risk Population And Low Birth Weight/Infant Mortality In A Northeast Oklahoma City Community, Estacia D. Thrower

McCabe Thesis Collection

Studies show that numerous and complex variables influence pregnancy outcomes and infant mortality rates. These variables include demographic, medical, physical, environmental, behavioral, and attitudinal factors and prenatal care. Improving the health of mothers and infants is a national challenge. In 1987, more than 3.8 million infants were born in the United States. Of these, 38,408 died before their first birthday. Although the infant mortality rate is at an all-time low, the pace of progress has slowed. According to Dr. Robert Deppen of the Oklahoma State Health Department, "In 1992, Oklahoma ranked 29th in the United States for infant mortality and …

Ultrasound Three- Dimensional Velocity Measurements By Feature Tracking, Gregory R. Bashford, Olaf T. Von Ramm

Biomedical Imaging and Biosignal Analysis Laboratory

This article describes a new angle-independent method suitable for three-dimensional (3-D) blood flow velocity measurement that tracks features of the ultrasonic speckle produced by a pulse echo system. In this method, a feature is identified and followed over time to detect motion. Other blood flow velocity measurement methods typically estimate velocity using one- (1-D) or two-dimensional (2-D) spatial and time information. Speckle decorrelation due to motion in the elevation dimension may hinder this estimate of the true 3-D blood flow velocity vector. Feature tracking is a 3-D method with the ability to measure the true blood velocity vector rather than …

The Effect Of Acute Low Ph On Feeding And Locomotor Activity Of Larval Fathead Minnows, Pimephales Promelas, Sharon Ore

Masters Theses & Specialist Projects

Lowered pH conditions in aquatic environments can have a negative impact on many aquatic organisms. In fish it has been shown that acidic water conditions may result in altered gill morphology, reduced reproductive success, changes in locomotor and feeding behavior and even death. Juveniles and adults have been the primary focus of research. However, the larval stage is potentially the most sensitive to toxicity. It is also important ontogenetically as several crucial development thresholds, such as first feeding, occur during this period. The impact of acute low pH on feeding performance was investigated in larval fathead minnows one to fifteen …

The Cloning And Characterization Of Toad-64: A Gene Expressed Transiently During Neuronal Differentiation In The Mammalian Nervous System, Jane Elizabeth Minturn

Yale Medicine Thesis Digital Library

During the development of the mammalian central nervous system, a pool of morphologically homogeneous, mitotically active progenitor cells in the neural tube gives rise to the enormously diverse population of postmitotic cells that assume the properties of neurons or glia. Postmitotic neurons elaborate processes that are involved in the migration of neurons to their adult positions as well as the elaboration of axonal and dendritic arbors that will ultimately form specific synaptic contacts. The generation of postmitotic neurons from precursor cells is a central differentiative event in development, but molecular markers of this event are few.Using 2D gel electrophoresis, proteins …

[Book Review Of] The Ethics Of Commercial Surrogate Motherhood: Brave New Families?, By Scott B. Rae, Richard K. Mansfield

The Linacre Quarterly

No abstract provided.

Serum Alpha 1 Antitrypsin And Pulmonary Emphysema, Anjum Shahid, Salimuddin Aziz, Sarwar J. Zuben, Anwar Ali Siddiqui, Musawir Ansari, Mohammed Anwar Waqar

Department of Biological & Biomedical Sciences

Using isoelectric focusing (lEE) and radial immunodiffusion (RID) techniques, serum samples from 100 normal healthy adults and 21 patients with pulmonary emphysema were analysed to identify varioud alpha 1 antitrypsin phenotypes and the Seru m concentrations,Ten percent of the patients had low serum values. The normal or most common genetic form, MM, is the predominant phenotype in both controls and patients (JPMA 46:102, 1996).

Ms211: Marnies, Armin Weinberg

Works on Radiation Effects: 1990-2020

This is a version of a paper on Chernobyl written by Marnie Rose a Russian Studies student who went to Bellaire High School, then UT (I think phase2) that Armin helped get her to study and visit Ukraine. Marnie unfortunately died of a glioblastoma when a Pediatric Resident at UT Houston. A fun run Run for the Rose is held in Houston each year in her memory. http://www.drmarnierose.org/. See more at Armin Weinberg, PhD Papers and its finding aid.

The Relationship Between The Fibrinogen D Domain Self-Association/Cross-Linking Site (Gammaxl) And The Fibrinogen Dusart Abnormality (Aalpha R554c-Albumin): Clues To Thrombophilia In The "Dusart Syndrome", Michael W. Mosesson, Kevin R. Siebenlist, James F. Hainfeld, J. S. Wall, C. Soria, J. P. Caen

Biomedical Sciences Faculty Research and Publications

Cross-linking of fibrinogen at its COOH-terminal gamma chain cross-linking site occurs in the presence of factor XIIIa due to self-association at a constitutive D domain site ("gammaXL"). We investigated the contribution of COOH-terminal regions of fibrinogen Aalpha chains to the gammaXL site by comparing the gamma chain cross-linking rate of intact fibrinogen (fraction I-2) with that of plasma fraction I-9, plasmic fraction I-9D, and plasmic fragment D1, which lack COOH-terminal Aalpha chain regions comprising approximately 100, approximately 390, and 413 residues, respectively. The cross-linking rates were I-2 > I-9 > 1-9D = D1, and indicated that the terminal 100 or more Aalpha …

Integrated Multimedia Timeline Of Medical Images And Data For Thoracic Oncology Patients, Denise R. Aberle, John David N. Dionisio, Michael F. Mcnitt-Gray, Ricky K. Taira, Alfonso F. Cárdenas, Jonathan G. Goldin, Kathleen Brown, Robert A. Figlin, Wesley W. Chu

Computer Science Faculty Works

A prototype multimedia medical database has been developed to provide image and textual data for thoracic oncology patients undergoing treatment of advanced malignancies. The database integrates image data from the hospital pieture archiving and communication system with textual reports from the radiology information system, alphanumeric data contained in the hospital information system, and other electronic medical data. The database presents information in a timeline format and also contains visualization programs that permit the user to view and annotate radiographic measurements in tabular or graphic form. The database provides an efficient and intuitive display of the changing status of oncology patients. …

A Comparative Study Of The Oxygen Uptake Between Nonmotorized And Motorized Treadmills, Michael S. Wood

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The purpose of this study was to determine the effects of nonmotorized treadmill walking and motorized treadmill walking on VO₂ results, measured in ml•kg^-1•min^-1, of males and females, ages 20-30 at Utah State University, Logan, Utah, USA. The participants were required to walk at a pace of 3 miles per hour and 13% grade for a total exercise time of 9 minutes. The exercise time was broken up with 3-minute recovery periods. Oxygen uptake was measured continuously using a metabolic measurement cart. The data obtained from the metabolic cart were correlated for each treadmill to …

A Test Of An Alternate Calibration Matrix For Niosh Method 7300, Robert T. Vitek

Community & Environmental Health Theses & Dissertations

The purpose of this study was to determine if the analytical results (when determining cadmium, lead, and zinc concentrations) for air sample filters prepared and analyzed according to N:OSH Method 7300, differ significantly, from those obtained when the instrument is calibrated using EPA Method 200.7 acid matrix standards. The null hypothesis was that no statistically significant difference, measured at the 95% confidence level, would exist between results obtained from the two calibration standards. Careful standard and sample preparation, the use of an internal standard, and the application of working standard and working internal standard correction factors served to isolate the …

Selecting Wilderness Areas To Conserve Utah's Biological Diversity, Diane W. Davidson, William D. Newmark, Jack W. Sites Jr., Dennis K. Shiozawa, Eric A. Rickart, Kimball T. Harper, Robert B. Keiter

Great Basin Naturalist

Congress is currently evaluating the wilderness status of Bureau of Land Management (BLM) public lands in Utah. Wilderness areas play many important roles, and one critical role is the conservation of biological diversity. We propose that objectives for conserving biodiversity on BLM lands in Utah be to (1) ensure the long-term population viability of native animal and plant species, (2) maintain the critical ecological and evolutionary processes upon which these species depend, and (3) preserve the full range of communities, successional stages, and environmental gradients. To achieve these objectives, wilderness areas should be selected so as to protect large, contiguous …

A Polymorphism Of A Platelet Glycoprotein Receptor As An Inherited Risk Factor For Coronary Thrombosis., Ethan J. Weiss, Paul F. Bray, Matthew Tayback, Steven P. Schulman, Thomas S. Kickler, Lewis C. Becker, James L. Weiss, Gary Gerstenblith, Pascal J. Goldschmidt-Clermont

Cardeza Foundation for Hematologic Research

BACKGROUND: Platelet glycoprotein IIb/IIIa is a membrane receptor for fibrinogen and von Willebrand factor, and it has an important role in platelet aggregation. It is known to be involved in the pathogenesis of acute coronary syndromes. Previously, we found a high frequency of a particular polymorphism, PlA2, of the gene encoding glycoprotein IIIa in kindreds with a high prevalence of premature myocardial infarction.

METHODS: To investigate the relation between the PlA2 polymorphism and acute coronary syndromes, we conducted a case-control study of 71 case patients with myocardial infarction or unstable angina and 68 inpatient controls without known heart disease. The …

Phenylbutyl Nitrone Compositions And Methods For Prevention Of Gastric Ulceration, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Compositions containing PBN, or active derivatives thereof, in a suitable pharmaceutical carrier for administration to a patient, are disclosed for treating or preventing gastric ulceration caused by ingestion of non-steroidal anti-inflammatories. Based on animal studies, the dosage is in the range of 3 to 300 mg/kg and is administered prior to, simultaneously, or shortly after ingestion of the NSAID compounds(s). In the preferred embodiment, the range is between 10 and 30 mg/kg, depending on the dosage unit required to protect the mucosa. The preferred method of administration is orally, alone or in combination with the non-steroidal anti-inflammatory. It is believed …

Toxoplasma Gondii-Induced Immune Suppression By Human Peripheral Blood Monocytes: Role Of Gamma Interferon., Jacqueline Y. Channon, Lloyd H. Kasper

Dartmouth Scholarship

The ability of Toxoplasma gondii to evade the host immune response during primary infection in humans is poorly understood. In murine toxoplasmosis, infected spleen macrophages release soluble factors that mediate a transient immunosuppression, which may allow the parasite to become established. When an enriched population of human monocytes from seronegative individuals was incubated with toxoplasmas in vitro, soluble factors that mediated market suppression of mitogen-induced lymphocyte DNA synthesis were released. Irradiated tachyzoites that do not undergo replication were sufficient stimuli for near-maximal soluble factor release. Up to 50% of the soluble factor-mediated suppression is attributable to a gamma interferon (IFN-gamma)-dependent …

The Chironian Vol. 113 Spring/Summer 1996, New York Medical College

The Chironian

No abstract provided.

Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 1996), Philadelphia College Of Osteopathic Medicine

Digest

The Spring 1996 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• President’s Perspective
• Primary Care Research
• College Board Profile
• PCOM Students Show their Diversity
• Alumni Board Profile
• Capital Campaign Developments
• Spring Convention Highlights
• Class Acts
• PCOM Merchandise
• Coming Events

A Tandem Duplication Within The Fibrillin 1 Gene Is Associated With The Mouse Tight Skin Mutation., Linda D. Siracusa, Rodney Mcgrath, Qing Ma, John J. Moskow, Jayanthi Manne, Paul J. Christner, Arthur M. Buchberg, Sergio A. Jimenez

Department of Medicine Faculty Papers

Mice carrying the Tight skin (Tsk) mutation have thickened skin and visceral fibrosis resulting from an accumulation of extracellular matrix molecules. These and other connective tissue abnormalities have made Tskl + mice models for scleroderma, hereditary emphysema, and myocardial hypertrophy. Previously we localized Tsk to mouse chromosome 2 in a region syntenic with human chromosome 15. The microfibrillar glycoprotein gene, fibrillin 1 (FBN1), on human chromosome 15q, provided a candidate for the Tsk mutation. We now demonstrate that the Tsk chromosome harbors a 30- to 40-kb genomic duplication within the Fbn1 gene that results in a larger than normal in-frame …