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Anorexia Nervosa : A Psychological Perspective Of Etiology And Current Treatment Procedures, Arlene Lagary

Graduate Research Papers

Anorexia nervosa is a chronic and sometimes fatal illness characterized by physical and psychological complications. Although no etiology for this illness has been determined, this paper presents a psychological etiology based on a synthesis of both traditional and current literature. The influence of culture, the therapeutic alliance, and client resistance are also considered. Relapse is common and the illness may last for many years. The health care community has addressed the complexity and chronicity of this illness by using a multi-component approach that includes psychoeducation, cognitive-behavioral therapy, psychodynamic interventions, family therapy, and psychopharmacology.

Differential Diagnosis Of Orofacial Pain I: Associated With Intracranial And Extracranial Structures And Psychogenic Disorders, Rodolfo Acosta-Ortiz

HPD Articles

Orofacial Pain (OFP) is a common problem among the general population and represents a condition that is potentially debilitating and deteriorating. The correct diagnosis is the principal base for an adequate management; in patients with DOF this may be a simple task or a very complex and frustrating experience for both, clinician, and patient. However, the clinician's knowledge of all possible pain condition that can affect the orofacial region can facilitate the diagnostic process. It is important to emphasize that is very difficult to diagnose something unknown for the clinician and even though "common things occur commonly", it is not …

Arbovirus Infection Increases With Group Size, Charles R. Brown, Nicholas Komar, Sunita B. Quick, Rajni A. Sethi, Nicholas A. Panella, Mary Bromberger Brown, Martin Pfeffer

Zoonotics and Wildlife Disease: Publications

Buggy Creek (BCR) virus is an arthropod-borne alphavirus that is naturally transmitted to its vertebrate host the cliff swallow (Petrochelidon pyrrhonota) by an invertebrate vector, namely the cimicid swallow bug (Oeciacus vicarius). We examined how the prevalence of the virus varied with the group size of both its vector and host. The study was conducted in southwestern Nebraska where cliff swallows breed in colonies ranging from one to 3700 nests and the bug populations at a site vary directly with the cliff swallow colony size. The percentage of cliff swallow nests containing bugs infected with BCR …

Tsc13p Is Required For Fatty Acid Elongation And Localizes To A Novel Structure At The Nuclear-Vacuolar Interface In Saccharomyces Cerevisiae, Sepp D. Kohlwein, Sandra Eder, Chan-Seok Oh, Charles E. Martin, Ken Gable, Dagmar Bacikova, Teresa Dunn

Uniformed Services University of the Health Sciences

The TSC13/YDL015c gene was identified in a screen for suppressors of the calcium sensitivity of csg2Δ mutants that are defective in sphingolipid synthesis. The fatty acid moiety of sphingolipids in Saccharomyces cerevisiae is a very long chain fatty acid (VLCFA) that is synthesized by a microsomal enzyme system that lengthens the palmitate produced by cytosolic fatty acid synthase by two carbon units in each cycle of elongation. The TSC13 gene encodes a protein required for elongation, possibly the enoyl reductase that catalyzes the last step in each cycle of elongation. The tsc13 mutant accumulates high levels of long-chain bases …

Introduction: Fear And Loathing Of Evolutionary Psychology In The Social Sciences, Daniel Leger, Alan Kamil, Jeffrey A. French

Department of Psychology: Faculty Publications

When one looks at the intellectual landscape of the modern university, at the scholarly and scientific interests of its faculty, the panorama is seamless. There are no discontinuities. The interests of physicists transmogrify into those of chemists, those of chemists into those of biologists, and so on. The lines, the divisions, between departments have been created out of administrative, not intellectual, necessity.
For example, consider the divide between chemistry and biology. There is a set of chemical processes that are characteristic of living systems. Is the study of these processes chemistry or biology? This is a meaningless question. To be …

Department Of Veterinary And Biomedical Sciences: 2001 Annual Report, John A. Schmitz

School of Veterinary and Biomedical Sciences: Information and History

Twenty Departmental students completed their Bachelor of Science in Agricultural Science degrees in 2001, nineteen in the Veterinary Science Major and one in the Veterinary Technologist Major. Twenty-five Nebraska residents were admitted into the College of Veterinary Medicine at Kansas State University, twelve of them having completed all or part of their pre-veterinary studies at UNL. Seven students completed their Master of Science degree in Veterinary Science. Enrollment in the Distance Education MS in Veterinary Science Master of Science, Distance Education Program increased to seven students, with several applications still being processed or expected. Three new Distance Education courses were …

Borrelia Lonestari Infection After A Bite By An Amblyomma Americanum Tick, Angela M. James, Dionysios Liveris, Gary P. Wormser, Ira Schwartz, Marisa A. Montecalvo, Barbara J. B. Johnson

United States Public Health Resources

Erythematous rashes that are suggestive of early Lyme disease have been associated with the bite of Amblyomma americanum ticks, particularly in the southern United States. However, Borrelia burgdorferi, the causative agent of Lyme disease, has not been cultured from skin biopsy specimens from these patients, and diagnostic serum antibodies usually have not been found. Borrelia lonestari sp nov, an uncultured spirochete, has been detected in A. americanum ticks by DNA amplification techniques, but its role in human illness is unknown. We observed erythema migrans in a patient with an attached A. americanum tick. DNA amplification of the flagellin gene …

Evidence For Nonacetylcholinesterase Targets Of Organophosphorus Nerve Agent: Supersensitivity Of Acetylcholinesterase Knockout Mouse To Vx Lethality, Ellen G. Duysen, Bin Li, Weihua Xie, Lawrence M. Schopfer, Robert S. Anderson, Clarence A. Broomfield, Oksana Lockridge

United States Public Health Resources

The possibility that organophosphate toxicity is due to inhibition of targets other than acetylcholinesterase (AChE, EC 3.1.1.7) was examined in AChE knockout mice. Mice (34–55 days old) were grouped for this study, after it was determined that AChE, butyrylcholinesterase (BChE), and carboxylesterase activities had reached stable values by this age. Mice with 0, 50, or 100% AChE activity were treated subcutaneously with the nerve agent VX. The LD₅₀ for VX was 10 to 12 µg/kg in AChE-/-, 17 µg/kg in AChE+/-, and 24 µg/kg in AChE+/- mice. The same cholinergic signs of toxicity were present in AChE-/- mice as …

Characterization Of Immunoglobulin Binding To Isolated Human Erythrocyte Membranes: Evidence For Selective, Temperature-Induced Binding Of Naturally Occurring Autoantibodies To The Cytoskeleton, James M. Salhany, Karen S. Cordes, Renee L. Sloan

United States Public Health Resources

Human plasma contains naturally occurring autoantibodies to the predominant components of the erythrocyte membrane: band 3 and spectrin bands 1 and 2 of the cytoskeleton. The titer of cytoskeletal plasma autoantibodies increases in various hemolytic conditions, suggesting that opsonization of the cytoskeleton may play an important role in the clearance of hemolyzed (not senescent) erythrocytes from the circulation. In this study, we use Alexa Fluor 488 goat anti-human IgG conjugate (Molecular Probes, Eugene, OR, USA), to characterize plasma immunoglobulin binding to erythrocyte membranes from osmotically hemolyzed cells (`ghosts'). The results show that exposure of ghosts to plasma results in 4-fold …

Context-Dependent Memory Under Stressful Conditions: The Case Of Skydiving, Laura A. Thompson, Keith L. Williams, Paul R. L'Esperance, Jerffrey Cornelius

Faculty Publications - College of Nursing

Two experiments examined the effect of differing levels of emotional arousal on learning and memory for words in matching and mismatching contexts. In Experiment 1, experienced skydivers learned words either in the air or on the ground and recalled them in the same context or in the other context. Experiment 2 replicated the stimuli and design of the first experiment except that participants were shown a skydiving video in lieu of skydiving. Recall was poor in air-learning conditions with actual skydiving, but when lists were learned on land, recall was higher in the matching context than in the mismatching context. …

Bovine Tuberculosis In Free-Ranging Carnivores From Michigan, Colleen S. Bruning-Fann, Stephen M. Schmitt, Scott D. Fitzgerald, Jean S. Fierke, Paul D. Friedrich, John B. Kaneene, Kathy A. Clarke, Kelly L. Butler, Janet B. Payeur, Diana L. Whipple, Thomas M. Cooley, Janice M. Miller, Darian P. Muzo

Michigan Bovine Tuberculosis Bibliography and Database

During a survey of carnivores and omnivores for bovine tuberculosis conducted in Michigan (USA) since 1996, Mycobacterium bovis was cultured from lymph nodes pooled from six coyotes (Canis latrans) (four adult female, two adult male), two adult male raccoons (Procyon lotor), one adult male red fox (Vulpes vulpes), and one 1.5-yr-old male black bear (Ursus americanus). One adult, male bobcat (Felis rufus) with histologic lesions suggestive of tuberculosis was negative on culture but positive for organisms belonging to the Mycobacterium tuberculosis complex when tested by polymerase chain reaction. All the …

The Regulation Of Manganese Superoxide Dismutase And Inducible Nitric Oxide Synthase By Nuclear Factor-Kappa B And Activator Protein 1 In Rat Aortic Endothelial Cells, Scott L. Cobbs

Theses, Dissertations and Capstones

Inducible nitric oxide synthase (iNOS) and manganese superoxide dismutase (MnSOD) are two enzymes that influence reactive oxygen species within the cell. The promoter regions for the genes encoding these enzymes have two specific transcription factor elements in common, activator protein 1 (AP-1) and nuclear factor kappa b (NF-KB). This study was initiated to determine if either NF-KB or AP-1 regulates the transcription of both genes in endothelial cells. To test whether NF-KB or AP-1 binding sites in the MnSOD and iNOS promoter region were important for transcriptional regulation, we performed induction analysis using various deletion constructs of MnSOD and iNOS …

Cationic Surfactant Mediated Hybridization And Hydrophobization Of Dna Molecules At The Liquid/Liquid Interface And Their Phase Transfer, Murali Sastry, Ashavani Kumar, Mrunalini Pattarkine, Vidya Ramakrishnan, Krishna N. Ganesh

Faculty Works

Hybridization of complementary oligonucleotides mediated by a cationic surfactant at the water/hexane interface leads to hydrophobic, double-helical DNA which may be readily phase transferred to the organic phase and cast into thin films on solid substrates.

Hormonal And Barrier Methods Of Contraception, Oncogenic Human Papillomaviruses, And Cervical Squamous Intraepithelial Lesion Development, Ann L. Coker, Laura C. Sanders, Sharon M. Bond, Tsilya Gerasimova, Lucia Pirisi

CRVAW Faculty Journal Articles

We assessed the influence of hormonal (oral, injectable, or levonorgestrel [Norplant, Wyeth-Ayerst, Philadelphia, PA]) and barrier methods of contraception on the risk of cervical squamous intraepithelial lesions (SIL), while adjusting for high-risk (HR) HPV infection. Subjects were women receiving family planning services through the state health department clinics from 1995 to 1998. We selected 60 cases with high-grade cervical/SIL (HSIL) and 316 with low-grade cervical/SIL (LSIL) and controls (427 women with normal cervical cytology) and analyzed cervical DNA for HR-HPV, using Hybrid Capture I (Digene; Gaithersburg, MD).When assessing ever use, duration, recency, latency, and age at first use, neither oral …

Cerumen Composition By Flash Pyrolysis-Gas Chromatography/Mass Spectrometry, Craig N. Burkhart, Michael A. Kruge, Craig G. Burkhart, Curtis Black

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Objective: To assess the chemical composition of cerumen by flash pyrolysis-gas chromatography/mass spectrometry.

Study Design: Collected earwax specimens were fractionated into residue and supernatant by means of deoxycholate. This natural bile acid produces significantly better disintegration of earwax in vitro than do presently available ceruminolytic preparations, and also has demonstrated excellent clinical results in vivo to date.

Patients: The sample for analysis was obtained from a patient with clinical earwax impaction.

Results: The supernatant is composed of simple aromatic hydrocarbons, C₅-C_{l 7} straight-chain hydrocarbons, a complex mixture of compounds tentatively identified as diterpenoids, …

The Case For Microbicides: A Global Priority, Kathy Attawell

HIV and AIDS

The HIV/AIDS epidemic continues to spread, undermining development, reversing health gains, and exacerbating poverty. It will be some time before a vaccine is available and accessible, thus there is an urgent need to identify additional prevention options, in particular a method that women control, which could save millions of lives. This report from the Population Council and International Family Health presents the case for microbicides—products used vaginally to prevent infection from HIV and other STIs in women and their sexual partners—and discusses recent progress and developments, outstanding challenges, and the action required to ensure that products will be made available …

Making A Difference For Children Affected By Aids: Baseline Findings From Operations Research In Uganda, Laelia Gilborn, Rebecca Nyonyintono, Robert Kabumbuli, Gabriel Jagwe-Wadda

HIV and AIDS

Many organizations and programs have begun to provide services and support to AIDS-orphaned children in East and southern Africa. Typical program components include the provision of school fees and supplies, supplementary feeding, home-visiting programs in which community members visit and assist affected children, and vocational training. However, few of these programs have been formally evaluated for impact. This paper reports on baseline findings from a study of two programs for AIDS-affected children and their families implemented by PLAN International in the Luwero and Tororo districts of Uganda. One program, referred to as orphan support, provides educational, health, and nutritional assistance …

Setting Limits: Medical Technology And The Law, George P. Smith Ii

Scholarly Articles

The allocation and rationing of health care resources is, no doubt, one of the most pressing issues confronting contemporary society. These issues considered from a micro and a macro level of economic analysis are linked inextricably to utilitarianism which, in turn, relies upon a cost-benefit analysis which balances reasonable individual needs against the availability of medical resources within the larger community. From an ethical viewpoint, the cost-benefit approach to the distribution of health care resources is impractical because it seeks to reduce (or convert) all health benefits to dollar amounts, thereby seeking very awkwardly to convert quality of life benefits …

Physical Therapy Alumni Survey, Laurie Holte

Physical Therapy Scholarly Projects

This alumni survey on which this independent study is based was developed and distributed by the University of North Dakota Department of Physical Therapy (UND-PT) as an outcomes assessment tool for program evaluation. The results will be used by the faculty to determine the answer to these three research questions: who are the UND-PT alumni as related to their practice patterns, what is the future of physical therapy as a profession, and how effective is the UND-PT program in educating proficient entry-level therapists. With this information, the department will be able to make curriculum modifications and be better prepared to …

Reliability And Validity Of Angular Joint Velocity Using Peak Motus 2000 Motion Analysis And Kin-Com Isokinetic Dynamometer, Mark Wagner

Physical Therapy Scholarly Projects

Background and Purpose: Use of motion analysis systems for the study of human motion in research settings and clinical settings is becoming more prevalent. In a traditional sense, motion analysis systems are used for gait analysis; most recently, they are being utilized to analyze spinal motion, foot motion, and components of motion during sporting activities. Questions about the accuracy of computerized motion analysis systems and the precision and reliability of the digitizing process remains. The purpose of this study is to determine the validity of the Peak Motus 2000 motion analysis system in calculating dynamic velocities and range of motion. …

A Mathematical Tumor Model With Immune Resistance And Drug Therapy: An Optimal Control Approach, Lisette G. De Pillis, Ami E. Radunskaya

All HMC Faculty Publications and Research

We present a competition model of cancer tumor growth that includes both the immune system response and drug therapy. This is a four-population model that includes tumor cells, host cells, immune cells, and drug interaction. We analyze the stability of the drug-free equilibria with respect to the immune response in order to look for target basins of attraction. One of our goals was to simulate qualitatively the asynchronous tumor-drug interaction known as “Jeffs phenomenon.” The model we develop is successful in generating this asynchronous response behavior. Our other goal was to identify treatment protocols that could improve standard pulsed chemotherapy …

Evidence For A Partially Folded Intermediate In Α-Synuclein Fibril Formation, Vladimir N. Uversky, Jie Li, Anthony L. Fink

Molecular Medicine Faculty Publications

Intracellular proteinaceous aggregates (Lewy bodies and Lewy neurites) of α-synuclein are hallmarks of neurodegenerative diseases such as Parkinson's disease, dementia with Lewy bodies, and multiple systemic atrophy. However, the molecular mechanisms underlying α-synuclein aggregation into such filamentous inclusions remain unknown. An intriguing aspect of this problem is that α-synuclein is a natively unfolded protein, with little or no ordered structure under physiological conditions. This raises the question of how an essentially disordered protein is transformed into highly organized fibrils. In the search for an answer to this question, we have investigated the effects of pH and temperature on the structural …

Is Congo Red An Amyloid-Specific Dye?, Ritu Khurana, Vladimir N. Uversky, Liza Nielsen, Anthony L. Fink

Molecular Medicine Faculty Publications

Congo red (CR) binding, monitored by characteristic yellow-green birefringence under crossed polarization has been used as a diagnostic test for the presence of amyloid in tissue sections for several decades. This assay is also widely used for the characterization of in vitro amyloid fibrils. In order to probe the structural specificity of Congo red binding to amyloid fibrils we have used an induced circular dichroism (CD) assay. Amyloid fibrils from insulin and the variable domain of Ig light chain demonstrate induced CD spectra upon binding to Congo red. Surprisingly, the native conformations of insulin and Ig light chain also induced …

Metal-Triggered Structural Transformations, Aggregation, And Fibrillation Of Human Α-Synuclein: A Possible Molecular Link Between Parkinson′S Disease And Heavy Metal Exposure, Vladimir N. Uversky, Jie Li, Anthony L. Fink

Molecular Medicine Faculty Publications

Parkinson's disease involves the aggregation of α-synuclein to form fibrils, which are the major constituent of intracellular protein inclusions (Lewy bodies and Lewy neurites) in dopaminergic neurons of the substantia nigra. Occupational exposure to specific metals, especially manganese, copper, lead, iron, mercury, zinc, aluminum, appears to be a risk factor for Parkinson's disease based on epidemiological studies. Elevated levels of several of these metals have also been reported in the substantia nigra of Parkinson's disease subjects. We examined the effect of various metals on the kinetics of fibrillation of recombinant α-synuclein and in inducing conformational changes, as monitored by biophysical …

2001 Apothecary, Southwestern Oklahoma State University

Apothecary

The 2001 Apothecary Staff would like to congratulate the graduating seniors. The years of hard work and dedication will provide the foundation for a successful career. With the knowledge obtained from Southwestern Oklahoma State University School of Pharmacy, each graduating senior is sure to become an intricate asset to the health care profession.

Vital Signs, Winter 2001, Boonshoft School Of Medicine

Vital Signs

A twenty-three page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes feature articles, a student profile, faculty notes, and more.

College Of Medical Sciences Student Handbook 2001-2002, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Antioxidation Activity Of Dhea And Its Mechanisms, Sun Yang, Han Rui

Pharmacy Faculty Articles and Research

Objective: The aim of this study was to determine the anti-oxidative activity of a new chemopreventive agent--dehydroepiandrosterone (DHEA), and the mechanisms of action by which DHEA protect the thymocytes and DNA from oxidative damage. Methods: Agarose gel electrophoresis, flow cytometry, single cel! gel electrophoresis, chemiluminescence assay, triazolyl blue tetrazolumbromide (MTT) colorimetry, and three dimensional collagen gel assay were used. Results: In agarose gel electrophoresis, 10 nmol/L DHEA blocked the typical DNA degradation (DNA Ladder) induced by H₂O₂. DHEA 2. 5 nmol/L and 10 nmol/L both significantly decreased the percentage of characteristic apoptotic DNA …

Catalog, Jefferson College Of Graduate Studies, 2001-2003, Jefferson College Of Graduate Studies

JCGS Administrative Documents & Policies

No abstract provided.

Psychosocial Impact Of Head Injury On The Family, Elizabeth Seccombe Palmer

Theses Digitization Project

No abstract provided.