Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences

Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 88951 - 88980 of 96688

Full-Text Articles in Entire DC Network

University Of Texas At Tyler Catalog, 2002-2004, University Of Texas At Tyler Jan 2002

University Of Texas At Tyler Catalog, 2002-2004, University Of Texas At Tyler

Catalogs

Archives Space instance: https://archivesspace.uttyler.edu/repositories/2/archival_objects/22361


Ε-Tubulin Is An Essential Component Of The Centriole, Susan K. Dutcher, Naomi S. Morrissette, Andrea M. Preble, Craig Rackley, John Stanga Jan 2002

Ε-Tubulin Is An Essential Component Of The Centriole, Susan K. Dutcher, Naomi S. Morrissette, Andrea M. Preble, Craig Rackley, John Stanga

Open Access Publications

No abstract provided.


Proteasome Regulates The Delivery Of Ldl Receptor-Related Protein Into The Degradation Pathway, Lora Melman, Hans J. Geuze, Yonghe Li, Lynn M. Mccormick, Peter Van Kerkhof, Ger J. Strous, Alan L. Schwartz, Guojun Bu Jan 2002

Proteasome Regulates The Delivery Of Ldl Receptor-Related Protein Into The Degradation Pathway, Lora Melman, Hans J. Geuze, Yonghe Li, Lynn M. Mccormick, Peter Van Kerkhof, Ger J. Strous, Alan L. Schwartz, Guojun Bu

Open Access Publications

No abstract provided.


Discrimination Between Paralogs Using Microarray Analysis: Application To The Yap1p And Yap2p Transcriptional Networks, Barak A. Cohen, Yitzhak Pilpel, Robi D. Mitra, George M. Church Jan 2002

Discrimination Between Paralogs Using Microarray Analysis: Application To The Yap1p And Yap2p Transcriptional Networks, Barak A. Cohen, Yitzhak Pilpel, Robi D. Mitra, George M. Church

Open Access Publications

No abstract provided.


Restrictions Limiting The Generation Of Dna Double Strand Breaks During Chromosomal V(D)J Recombination, Robert E. Tillman, Andrea L. Wooley, Maureen M. Hughes, Tara D. Wehrly, Wojciech Swat, Barry P. Sleckman Jan 2002

Restrictions Limiting The Generation Of Dna Double Strand Breaks During Chromosomal V(D)J Recombination, Robert E. Tillman, Andrea L. Wooley, Maureen M. Hughes, Tara D. Wehrly, Wojciech Swat, Barry P. Sleckman

Open Access Publications

No abstract provided.


Outlook Magazine, Fall 2002 Jan 2002

Outlook Magazine, Fall 2002

Outlook Magazine

No abstract provided.


Actiononaias Ligamentina As A Biomonitor In The Green River: An Unique Approach For Analysis Of Environmental Impacts, Robert Kirkland Jan 2002

Actiononaias Ligamentina As A Biomonitor In The Green River: An Unique Approach For Analysis Of Environmental Impacts, Robert Kirkland

Masters Theses & Specialist Projects

Biomonitoring has become an important component in bioassessment programs. It is used to maintain high water quality standards, and determine contaminant levels and biological affects in areas that have been heavily disturbed. The objectives of this research were 1) to improve and apply certain modern biomonitoring techniques and 2) to locate possible contaminant sources affecting the flora and fauna of the Green River and of Mammoth Cave. Actinonaias ligamentina (Lamarck, 1819), a freshwater mussel, was used for interpretation of these impacts as well as refinement of biomonitoring techniques. The mussels were collected in the Lawler Bend region of the Green …


Characteristic Differences Between Parents/Guardians Who Keep Immunization Records And Those Who Do Not, Rebecca Bonilla Mangual Jan 2002

Characteristic Differences Between Parents/Guardians Who Keep Immunization Records And Those Who Do Not, Rebecca Bonilla Mangual

Theses Digitization Project

No abstract provided.


Health Disparities, Neil Macnaughton Jan 2002

Health Disparities, Neil Macnaughton

International Journal of Global Health

"Americans believe that we are a classless society, largely because just about everyone thinks they are members of the struggling middle class. In actuality the United States is a highly stratified society in terms of wealth, meaning that we have a much more significant problem of poverty than most industrialized nations. Members of ethnic minorities are more likely to be poorer and less powerful. Racist beliefs on the part of the dominant white ethnic groups exacerbate the problem of socioeconomic inequality (Brown, 1998 p. 259)." In healthcare we like to believe that we do not discriminate amongst patient populations and …


Unbuckling The Chemical Straitjacket: The Legal Significance Of Recent Advances In The Pharmacological Treatment Of Psychosis, Douglas Mossman Md Jan 2002

Unbuckling The Chemical Straitjacket: The Legal Significance Of Recent Advances In The Pharmacological Treatment Of Psychosis, Douglas Mossman Md

Faculty Articles and Other Publications

Antipsychotic medications figure prominently in the rapidly-growing field of mental disability law. Although the properties of antipsychotic medications are medical matters, legal scholars, judges, and practicing attorneys often need to understand what these drugs do. Yet the legal database - the principal or sole information source cited and consulted by legal thinkers - is often a source of confusion or misinformation about the actions of antipsychotic drugs and the scientific basis for prescribing them. The potential for misunderstanding antipsychotic treatment has increased since the arrival of "novel" or "aytpical" antipsychotic drugs, which cause fewer side effects than drugs that were …


Gender Differences In Gross And Fine Motor Abilities In Preschool Aged Children In West Virginia, Kelly R. Pennington Jan 2002

Gender Differences In Gross And Fine Motor Abilities In Preschool Aged Children In West Virginia, Kelly R. Pennington

Theses, Dissertations and Capstones

The purpose of this study was to investigate gender differences in gross and fine motor abilities in preschool aged children in West Virginia. Subjects consisted of 21 males and 16 females. Data was collected via the West Virginia Educare Initiative using the Carolina Curriculum for Preschoolers with Special Needs. Results of this study indicate that there are no significant gender differences in either gross motor or fine motor abilities in preschool aged children.


Frequency Of Use Of Complementary And Alternative Medicine In Women With Breast Cancer, Cecile A. Lengacher, Mary Bennett, Kevin E. Kip, Rosemary Keller, Melisa S. Lavance, Lynette S. Smith, Charles E. Cox Jan 2002

Frequency Of Use Of Complementary And Alternative Medicine In Women With Breast Cancer, Cecile A. Lengacher, Mary Bennett, Kevin E. Kip, Rosemary Keller, Melisa S. Lavance, Lynette S. Smith, Charles E. Cox

Nursing Faculty Publications

No abstract provided.


Associations Between Water-Treatment Methods And Diarrhoea In Hiv-Positive Individuals, J. N. S. Eisenberg, T. J. Wade, A. Hubbard, D. I. Abrams, R. J. Leiser, S. Charles, M. Vu, S. Saha, C. C. Wright, Deborah A. Levy, P. Jensen, J. M. Colford Jan 2002

Associations Between Water-Treatment Methods And Diarrhoea In Hiv-Positive Individuals, J. N. S. Eisenberg, T. J. Wade, A. Hubbard, D. I. Abrams, R. J. Leiser, S. Charles, M. Vu, S. Saha, C. C. Wright, Deborah A. Levy, P. Jensen, J. M. Colford

Journal Articles: Epidemiology

This manuscript extends our previously published work (based on data from one clinic) on the association between three drinking water-treatment modalities (boiling, filtering, and bottling) and diarrhoeal disease in HIV-positive persons by incorporating data from two additional clinics collected in the following year. We conducted a cross-sectional survey of drinking water patterns, medication usage, and episodes of diarrhoea among HIV-positive persons attending clinics associated with the San Francisco Community Consortium. We present combined results from our previously published work in one clinic (n = 226) with data from these two additional clinics (n = 458). In this combined analysis we …


Reactive Attachment Disorder : Diagnosis, Assessment, And Treatment, Kimberly A. Rees Jan 2002

Reactive Attachment Disorder : Diagnosis, Assessment, And Treatment, Kimberly A. Rees

Graduate Research Papers

In recent years, there has been an increasing trend toward the use of Reactive Attachment Disorder (RAD) as a diagnosis to describe myriad problem behaviors and disturbed interactions between infants, young children and their caregivers. There is considerable disagreement about what RAD actually entails and, in particular, what types of assessments and treatment interventions to use with affected children and families (Hanson & Spratt, 2000). This paper is intended to clarify what the current research states about Reactive Attachment Disorder. It includes the definitions and diagnosis, importance of attachment, biological components, risk factors later in life, assessment, and treatment available …


A History Of Quality Of Life Measurements, Jordan Matthew Prutkin, Alvan R. Feinstein Jan 2002

A History Of Quality Of Life Measurements, Jordan Matthew Prutkin, Alvan R. Feinstein

Yale Medicine Thesis Digital Library

Purpose: To review the origins and early development of quality of life measurements in the medical literature. Methods: A comprehensive literature review of Medline from 1966-1986 examining articles with quality of life as a subject heading. Studies were included if they were the original article describing a scales development or used scales developed in the social science literature. Results: The measurements have been derived from two separate sources: a transfer and expansion of medical appraisals for health status, and an application of sociometric and psychometric methods for populational assessment of happiness, well-being, and other affects. Neither source of measurements used …


Possibilities For Refinement And Reduction: Future Improvements Within Regulatory Testing, Martin L. Stephens, Kathleen Conlee, Gina Alvino, Andrew N. Rowan Jan 2002

Possibilities For Refinement And Reduction: Future Improvements Within Regulatory Testing, Martin L. Stephens, Kathleen Conlee, Gina Alvino, Andrew N. Rowan

Experimentation Collection

Approaches and challenges to refining and reducing animal use in regulatory testing are reviewed. Regulatory testing accounts for the majority of animals reported in the most painful and/or distressful categories in the United States and Canada. Refinements in testing, including the use of humane endpoints, are of increasing concern. Traditional approaches to reduction (e.g., improving experimental design) are being supplemented with complementary approaches, such as the use of tier testing to eliminate some chemicals prior to in vivo testing. Technological advances in telemetry and noninvasive techniques will help decrease either the demand for animals in testing or animal suffering. Further …


Predicting The Spatial Dynamics Of Rabies Epidemics On Heterogeneous Landscapes, David L. Smith, Brendan Lucey, Lance A. Waller, James E. Childs, Leslie A. Real Jan 2002

Predicting The Spatial Dynamics Of Rabies Epidemics On Heterogeneous Landscapes, David L. Smith, Brendan Lucey, Lance A. Waller, James E. Childs, Leslie A. Real

Zoonotics and Wildlife Disease: Publications

Often as an epidemic spreads, the leading front is irregular, reflecting spatial variation in local transmission rates. We developed a methodology for quantifying spatial variation in rates of disease spread across heterogeneous landscapes. Based on data for epidemic raccoon rabies in Connecticut, we developed a stochastic spatial model of rabies spread through the state’s 169 townships. We quantified spatial variation in transmission rates associated with human demography and key habitat features. We found that large rivers act as semipermeable barriers, leading to a 7-fold reduction in the local rates of propagation. By combining the spatial distribution of major rivers with …


Preclinical Diagnosis Of Chronic Wasting Disease In Captive Mule Deer (Odocoileus Hemionus) And White-Tailed Deer (Odocoileus Virginianus) Using Tonsillar Biopsy, Margaret A. Wild, Terry R. Spraker, Christina J. Sigurdson, Katherine I. O'Rourke, Michael W. Miller Jan 2002

Preclinical Diagnosis Of Chronic Wasting Disease In Captive Mule Deer (Odocoileus Hemionus) And White-Tailed Deer (Odocoileus Virginianus) Using Tonsillar Biopsy, Margaret A. Wild, Terry R. Spraker, Christina J. Sigurdson, Katherine I. O'Rourke, Michael W. Miller

Zoonotics and Wildlife Disease: Publications

The usefulness of tonsillar biopsy on live deer for preclinical diagnosis of the transmissible spongiform encephalopathy chronic wasting disease (CWD) was evaluated. Disease was tracked in a CWD-endemic herd using serial tonsillar biopsies collected at 6 to 9 month intervals from 34 captive mule deer (Odocoileus hemionus) and five white-tailed deer (O. virginianus). Tonsillar biopsies were examined for accumulation of PrPCWD, the protein marker for infection, using immunohistochemical (IHC) staining. 26/34 (76%) mule deer and 4/5 (80%) white-tailed deer had PrPCWD accumulation in tonsillar biopsies; CWD was subsequently confirmed by post-mortem examination in …


Pregnancy Status And Fetal Prion Genetics Determine PrpSc Accumulation In Placentomes Of Scrapieinfected Sheep, Wenbin Tuo, Katherine I. O'Rourke, Dongyue Zhuang, William P. Cheevers, Terry R. Spraker, Donald P. Knowles Jan 2002

Pregnancy Status And Fetal Prion Genetics Determine PrpSc Accumulation In Placentomes Of Scrapieinfected Sheep, Wenbin Tuo, Katherine I. O'Rourke, Dongyue Zhuang, William P. Cheevers, Terry R. Spraker, Donald P. Knowles

Zoonotics and Wildlife Disease: Publications

Ovine scrapie is a fatal neurodegenerative disorder that may be transmitted through exposure to infected uterine and placental tissues. Susceptibility to scrapie is primarily controlled by polymorphisms in the prion protein (PrP) gene. Scrapie in the U.S. Suffolk breed and in many breeds in Europe occurs in sheep homozygous for glutamine (171QQ), but rarely in sheep heterozygous for glutamine and arginine (171QR) or homozygous for arginine (171RR) at codon 171 of the PrP gene. This study demonstrated that accumulation of PrPSc in uterine-placental epithelial cells in the placentome was determined by fetal PrP genotype and the pregnancy status of …


One Year After 9/11: The Impact Of Global Terrorism On Public Health Education, Joseph K. Ogah Jan 2002

One Year After 9/11: The Impact Of Global Terrorism On Public Health Education, Joseph K. Ogah

International Journal of Global Health

As we mark one year after the September 11 (9/11) attack of the World Trade Center in New York, and the killing or traumatizing of thousands of innocent persons, global terrorism remains an issue of concern for political leaders, the business world and educators. The implications of terrorism to public health education are many and varied. At the minimum, 9/11 increased the immediate need for additional public health education to help people cope and deal with both the immediate and long-term effects of terrorist acts all over the world. Public health education plays a leading role in managing the fear …


Invisible, Underserved, And Diverse: The Health Of Women In Prison, Janette Y. Taylor, Rachel Williams, M. J. Eliason Jan 2002

Invisible, Underserved, And Diverse: The Health Of Women In Prison, Janette Y. Taylor, Rachel Williams, M. J. Eliason

International Journal of Global Health

In the United States of America, women are the fastest growing segment of the criminal justice system. They are entering the system with far greater physical and mental health problems than men, but with fewer health services. Additionally, within this expanding population of incarcerated women, are disproportionately represented poor women of color with serious health needs. This article: a) uses an ecosocial model to examine and critique the health and healthcare of women in prison, b) examines social structures that influence incarceration and health status, and c) proposes reconsideration of current prison health services and education.


Regulation Of Cardiomyocyte Cell Death In Culture, Deanna Lund Jan 2002

Regulation Of Cardiomyocyte Cell Death In Culture, Deanna Lund

All Volumes (2001-2008)

Heart failure is the inability of body's cardiac output to keep pace with its demand for supplies and waste removal. It is characterized by systolic and diastolic ventricular dysfunction, cardiac remodeling, myocyte loss and fibrosis (Nyquist-Battie et al, 1996). It is accompanied by an increase in sympathetic activity with measurable increases in circulating plasma norepinephrine levels (Hasegawa et al. 2001; Kaye et al., 1995). Previous studies have suggested that adrenergic agonists play a role in myocardial cell death. Mann et al. (1992) have shown that increased activation of the adrenergic signaling pathway causes necrotic as well as apoptotic death in …


College Of Optometry Program Overview, Nova Southeastern University Jan 2002

College Of Optometry Program Overview, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.


Synthesis And Chemistry Of Naphthalene Annulated Trienyl Iron Complexes: Potential Anticancer Dna Alkylation Reagents, Traci Means Jan 2002

Synthesis And Chemistry Of Naphthalene Annulated Trienyl Iron Complexes: Potential Anticancer Dna Alkylation Reagents, Traci Means

Inquiry: The University of Arkansas Undergraduate Research Journal

Iron complex chemistry that opens a new door to the medicinal and pharmaceutical worlds is the aim of this research. Specifically, ortho-quinone methide moieties are intermediates in several antitumor drugs and have been identified as bioreductive alkylators of DNA. In our research, a class of iron compounds has been targeted to resemble these quinone methides. It is hoped that these new compounds could be modified to provide a window of opportunity toward the discovery of a selective mode of drug delivery. We have focused our efforts on generating a reactive transition metal complexed 5-membered ring analog of o-quinone methide based …


Pick-Me-Up Newsletter - Issue 5 , Volume 1, Nova Southeastern University Jan 2002

Pick-Me-Up Newsletter - Issue 5 , Volume 1, Nova Southeastern University

Pick Me Up Newsletter

No abstract provided.


College Of Pharmacy Student Handbook July 2002, Nova Southeastern University Jan 2002

College Of Pharmacy Student Handbook July 2002, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.


Virginia Dental Journal (Vol. 79, No. 2, 2002) Jan 2002

Virginia Dental Journal (Vol. 79, No. 2, 2002)

Virginia Dental Journal

No abstract provided.


Ritalin And The Child, Valerie Vickers Jan 2002

Ritalin And The Child, Valerie Vickers

Theses, Dissertations and Capstones

This study focuses on Attention Deficit Hyperactivity Disorder (ADHD) the history of the disease, sufferers, individual accounts from sufferers, and both positive outcomes and negative repercussions of its treatment. Extensive secondary research and the collection of a personal account form the body of the work. The information focuses attention on key points regarding the historical background of ADHD, including: the discovery of the disease, change in categories of drugs used to control it, and the rate of evolution in thoughts on and treatment of the disease. Also researched are the various guidelines as well as ignored factors in the diagnosing …


A New Class Of Lipid Desaturase Central To Sphingolipid Biosynthesis And Signalling, Johnathan A. Napier, Louise V. Michaelson, Teresa M. Dunn Jan 2002

A New Class Of Lipid Desaturase Central To Sphingolipid Biosynthesis And Signalling, Johnathan A. Napier, Louise V. Michaelson, Teresa M. Dunn

Uniformed Services University of the Health Sciences

Sphingolipids and their phosphorylated metabolites play crucial roles in intracellular signaling in animals, and evidence is emerging for analogous situations in fungi and plants. Central to this signaling pathway is the phosphorylation of the sphingoid long chain base, sphingosine, which yields sphingosine-1-phosphate. Until recently, the enzyme responsible for the biosynthesis of sphingosine was unknown, but the Δ4-long chain base desaturase that carries out this reaction has now been identified. Orthologues are present in animals, plants and fungi, raising the possibility of using reverse genetics to determine the contribution of sphingosine-1-phosphate to signaling networks.


A Saccharomyces Cerevisiae Gene Required For Heterologous Fatty Acid Elongase Activity Encodes A Microsomal Β-Keto-Reductase, Frédéric Beaudoin, Ken Gable, Olga Sayanova, Teresa Dunn, Johnathan A. Napier Jan 2002

A Saccharomyces Cerevisiae Gene Required For Heterologous Fatty Acid Elongase Activity Encodes A Microsomal Β-Keto-Reductase, Frédéric Beaudoin, Ken Gable, Olga Sayanova, Teresa Dunn, Johnathan A. Napier

Uniformed Services University of the Health Sciences

A number of Saccharomyces cerevisiae membranebound oxidoreductases were examined for potential roles in microsomal fatty acid elongation, by assaying heterologous elongating activities in individual deletion mutants. One yeast gene, YBR159w, was identified as being required for activity of both the Caenorhabditis elegans elongase PEA1 (F56H11.4) and the Arabidopsis thaliana elongase FAE1. Ybr159p shows some limited homology to human steroid dehydrogenases and is a member of the short-chain alcohol dehydrogenase superfamily. Disruption of YBR159w is not lethal, in contrast to previous reports, although the mutants are slow growing and display high temperature sensitivity. Both …