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Phosphoglycan Messengers And Their Medical Uses (Sle), Khalid M. Elased, Khalid A. Gumaa, Hassan Rahmoune, Thomas Rademacher, J. B. De Souza

Pharmacology and Toxicology Faculty Publications

PPhosphoglycan messengers (PGMs) which are carbohydrate derivatised phosphatidyl cyclitols are disclosed, together with the finding that these substances are biologically active, especially in modulating plasma cholesterol, plasma triglycerides and/or high density lipoprotein levels and/or modulating the LDL:HDL ratio, and for the treatment of lipodystrophy or dyslipidemia. These compounds are distinct from GPI-anchors disclosed in the prior art as these GPI-anchors are protein linked and are not biologically active.

Caduceus 2002, Stritch School Of Medicine

Stritch School of Medicine Yearbooks

No abstract provided.

Holistic Approach To Mental Illnesses At The Toby Of Ambohibao Madagascar, Daniel A. Rakotojoelinandrasana

Doctor of Ministry Theses

The Church is to reclaim its teaching and praxis of the healing ministry at the example of Jesus Christ who preached, taught and healed. Healing is holistic, that is, caring for the whole person, physical, mental, social and spiritual. Healing is a part of the full salvation in Jesus Christ.

Mental illnesses or disorders affect one fourth of human beings in the world and their prevalence is far from declining. This thesis describes the model of Ambohibao and suggests it as a way for the church to do healing ministry, and particularly, as a way to approach the problems of …

Healthnet News V.17:No.4 Winter 2002, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services.

Estimating Causal Parameters In Marginal Structural Models With Unmeasured Confounders Using Instrumental Variables, Tanya A. Henneman, Mark Johannes Van Der Laan, Alan E. Hubbard

U.C. Berkeley Division of Biostatistics Working Paper Series

For statisticians analyzing medical data, a significant problem in determining the causal effect of a treatment on a particular outcome of interest, is how to control for unmeasured confounders. Techniques using instrumental variables (IV) have been developed to estimate causal parameters in the presence of unmeasured confounders. In this paper we apply IV methods to both linear and non-linear marginal structural models. We study a specific class of generalized estimating equations that is appropriate to these data, and compare the performance of the resulting estimator to the standard IV method, a two-stage least squares procedure. Our results are applied to …

Two Concepts Of Immortality: Reframing Public Debate On Stem-Cell Research, Frank Pasquale

Faculty Scholarship

Regenerative medicine seeks not only to cure disease, but also to arrest the aging process itself. So far, public attention to the new health care has focused on two of its methods: embryonic stem-cell research and therapeutic cloning. Since both processes manipulate embryos, they alarm those who believe life begins at conception. Such religious objections have dominated headlines on the topic, and were central to President George W. Bush's decision to restrict stem-cell research.

Although they are now politically potent, the present religious objections to regenerative medicine will soon become irrelevant. Scientists are fast developing new ways of culturing the …

Parenting In The Face Of Prejudice: The Need For Representation For Parents With Mental Illness, Leigh S. Goodmark

Faculty Scholarship

No abstract provided.

West Virginia Registered Dietitians' Knowledge And Attitudes Of Diabetes Care, Marie R. Gravely

Theses, Dissertations and Capstones

This study addresses diabetes knowledge and attitudes of West Virginia dietitians as they relate to Medicare certified provider guidelines. A questionnaire was developed using the Diabetes Attitude Scale, questions from A CORE Curriculum for Diabetes Education, and demographic questions addressing length and type of practice, route to registration, and specialty credentials. Responses were analyzed to determine overall knowledge and attitude as well as how demographic information affects knowledge and attitude. Results indicated demographic information (except for specialty credentials and hours working with diabetes) did not have a significant effect on the dietitian’s diabetes knowledge and attitude. Specialty credentials did have …

A Mechanistic Study Of Myoglobin Nephrotoxicity, Jennifer L. Minigh

Theses, Dissertations and Capstones

Myoglobin is an endogenous protein that can become nephrotoxic under certain conditions such as crush injuries, drug overdose, and seizures where prolonged contraction of muscle leads to cell death and leakage of myoglobin. The mechanism of myoglobin-induced nephrotoxicity is not fully understood. The purpose of this study was to characterize the sequence and mechanistic events associated with the in vitro toxicity of myoglobin in renal cortical slices. Renal tissue was isolated from Fischer 344 rats. Slices of renal cortex were prepared by freehand. These slices were then incubated for 60-180 minutes with myoglobin (0-12 mg/mL) pretreated with 4 mM ascorbic …

Pkcα Translocation And Actin Remodeling In Contracting A7r5 Smooth Muscle Cells, Chenwei Li

Theses, Dissertations and Capstones

Recent research indicates that protein kinase C (PKC) plays an important role in smooth muscle contraction. Because PKC activation and specificity of substrate phosphorylation is believed to be associated with the relocalization of the enzyme to specific cell sites, we first investigated the subcellular translocation of PKCα in A7r5 smooth muscle cells by confocal microscopy through use of standard immunohistologic staining and PKCα - enhanced green fluorescent protein (PKCα -EGFP) fusion protein expression. PKCα was diffusely distributed throughout the cytosol in the unstimulated A7r5 cell. Upon stimulation with phorbol 12, 13 dibutyrate (PDBu), PKCα was translocated primarily to either the …

Characterization Of Host-Bacteria Interactions Contributing To Group B Streptococcus Colonization, Jennifer Marie Smith

Theses, Dissertations and Capstones

Group B streptococcus (GBS) is the leading cause of life-threatening bacterial infections during the first three months of life. GBS is also a frequent cause of maternal postpartum infections. Both types of infections stem from maternal vaginal and/or rectal colonization with GBS in the perinatal period. Limited information is available concerning how the colonization process occurs and what role the host immune system may play in the establishment of persistent colonization by GBS. The complex interactions between the immune system and GBS normally should end in clearance of the bacteria. However, since colonization by GBS occurs in a large number …

Gravistimulation Of Pisum Sativum And Expression Of The Cell Membrane Expansin Proteins, Sherrine A. Ibrahim

Theses, Dissertations and Capstones

This thesis research investigates the regulation of gene expression in pea stems (Pisum sativum) after changes in orientation to gravity (gravistimulation). Specifically, this project examines the changes in extracellular soluble proteins due to gravistimulation in pea seedlings. This change in gravity alters the cellular growth pattern, which can be directly linked to enzymatic activity resulting in the expression of cell wall loosening proteins called expansins. This loosening of the cell wall matrix subsequently increases elasticity in growing cells, thus leading to an upward curvature of the stems. These changes in enzymatic activity and gene expression are crucial for …

2001 Cancer Care Annual Report, Children's Mercy Hospital

Cancer Center Annual Reports

Annual report of cancer care and oncology services at the Children's Mercy Hospital, Kansas City MO, a pediatric medical center, with a focus on Wilms' Tumor.

Information Interface - Volume 30, Issue 1 - January/February 2002, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users.

Articulations 2002, Som School Of Osteopathic Medicine, Umdnj University Of Medicine And Dentistry Of Nj

Yearbooks

University of Medicine and Dentistry of New Jersey (UMDNJ) School of Osteopathic Medicine yearbook for the class of 2002. 128 pages.

Contents: Osteopathic Oath p.1, UMDNJ-SOM Campus p. 2, UMDNJ-SOM Affiliates p. 3, Dean's Message p. 4, Administration p. 5, Faculty p. 6, Candids p. 17, Graduates p. 34, Convocation and Graduation p. 114, Editor's Page p. 120.

Glutamine Uptake By Neurons: Interaction Of Protons With System A Transporters, Farrukh A. Chaudhry, Dietmar Schmitz, Richard J. Reimer, Peter Larsson, Andrew T. Gray, Roger Nicoll, Michael Kavanaugh, Robert H. Edwards

Biomedical and Pharmaceutical Sciences Faculty Publications

Astrocytes provide the glutamine required by neurons to synthesize glutamate and GABA. However, the mechanisms involved in glutamine transfer from glia to neurons have remained poorly understood. Recent work has implicated the System N transporter SN1 in the efflux of glutamine from astrocytes and the very closely related System A transporters SA1 and SA2 in glutamine uptake by neurons. To understand how these closely related proteins mediate flux in different directions, we have examined their ionic coupling. In contrast to the electroneutral exchange of H⁺ for Na⁺ and neutral amino acid catalyzed by SN1, we now show that …

Dynamic Equilibrium Between Coupled And Uncoupled Modes Of A Neuronal Glutamate Transporter, Lars Borre, Michael Kavanaugh, Baruch I. Kanner

Biomedical and Pharmaceutical Sciences Faculty Publications

In the brain, the neurotransmitter glutamate is removed from the synaptic cleft by (Na⁺ + K⁺)-coupled transporters by an electrogenic process. Moreover, these transporters mediate a sodium- and glutamate-dependent uncoupled chloride conductance. In contrast to the wild type, the uptake of radiolabeled substrate by the I421C mutant is inhibited by the membrane-impermeant [2-(trimethylammonium)ethyl]methanethiosulfonate and also by other sulfhydryl reagents. In the wild-type and the unmodified mutant, substrate-induced currents are inwardly rectifying and reflect the sum of the coupled electrogenic flux and the anion conductance. Remarkably, the I421C mutant modified by sulfhydryl reagents exhibits currents that are non-rectifying …

College Of Pharmacy Program Overview, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Dentalgram - Vol. 16, No. 01, Loma Linda University School Of Dentistry

Dentalgram

In this issue:

• SAC-Norton dental clinic provides much needed care
• Alumni-Student Convention, 2002
• IDP holds graduation banquet
• Strategic Planning Update column
• Department news
• Recent publications
• Toot your own horn!
• Saul Martinez Elementary School
• Christmas breakfast

Concentrations Of Hair Minerals Determined By Inductively Coupled Plasma-Mass Spectrometry In People With Headaches, Joel R. Mundall

Capstone Research Projects

Calculations were made to determine what relationships exist between headaches and hair mineral levels of 1,995 hair tissue mineral analyses by inductively coupled plasma-mass spectrometry. Of the 1,995 samples (1,089 females, 906 males), 163 (100 females, 63 males) were taken from patients who had been diagnosed with headaches. Above average hair levels of bismuth and the earth metals were found among the both the males and females of the headache group. An age correlation analyses showed highest headache incidence in teens and early forties. A direct correlation was also found between calcium and magnesium levels, which peaked in the late …

College Of Pharmacy Overview In Ponce, Puerto Rico, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

College Of Dental Medicine Overview 2002, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Attachment Disorders And Personality Disorders : A Possible Connection, Jen Sacora

Graduate Research Papers

Researchers now propose that attachment theory can be applied beyond childhood. They believe attachment exists in adulthood and influences adult relationships. Possible connections between personality disorders and well-known approaches to personality development such as attachment theory have been made (Brennan & Shaver, 1998).

The purpose of this paper is to examine the relationships between parent-infant attachment which influence adult relationships and psychopathology. Theories of personality development as they relate to attachment will be explored as well as influence of early childhood experiences on personality. Finally, possible connections between attachment disorders and personality disorders will be speculated.

College Of Dental Medicine Student Handbook July 2002, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Adolescent Substance Use And Abuse, Finn Green

Kaleidoscope

No abstract provided.

College Of Osteopathic Medicine Program Overview, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

The Effects Of The "Get Off Your Rocker" Exercise Class On Balance, Heather Bethard, Trish Magee, Susie Mcgarry, Sarah Mcguire

Physical Therapy Scholarly Projects

The purpose of this study was to determine if the six-week "Get Off Your Rocker" balance exercise class, promoted by HealthSouth®, had a significant effect on balance in the geriatric population. If proven to be effective, this class could be an additional tool for physical therapists to utilize to aid in improving a patient's balance.

A total of 22 subjects volunteered to participate in this study. They were randomly divided into two groups: a control group (n=1 0, 8 females and 2 males) and an exercise group (n=12, 8 females and 4 males). All subjects were high functioning and were …

Depot Medroxyprogesterone Acetate Discontinuation After Weight Gain In 17-19 Year Old Adolescent Girls, Donna Lea Church

Theses Digitization Project

Depot medroxyprogesterone acetate (DMPA) is a long acting progesterone only contraceptive agent. Side effects such as irregular bleeding patterns and weight gain are attributed to discontinuation. The purpose of this study was to describe depot medroxyprogesterone acetate discontinuation after weight gain in 17 to 19 year-old adolescent girls.

Development And Coordination Of A Health Care Services Program For Foster Children In A Shelter Care Population, Rebecca Lynne Allen Spradling

Theses Digitization Project

The purpose of this project is to support health promotion of children entering foster care, ensure that children receive all health care services needed, prevent the trauma of duplication of immunizations, and reduce disruption of health care as children move through the foster care system.

End Of Life Nursing Education Consortium Grant Implementation Project, Sheryl Ramona Terkildsen

Theses Digitization Project

This project addressed the continuing education needs of nursing staff and other health care professionals for delivering competent and compassionate palliative or end of life care. The scope of the project included, writing a grant application, training and certification by the end of life Nursing Education Consortium and implementing an education program for staff at the Loma Linda Veterans Affairs medical center.