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College Of Optometry Student Handbook July 2002, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

College Of Allied Health Student Handbook July 2002, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Reducing Childhood Pedestrian Injuries: Proceedings Of A Multidisciplinary Conference, Richard A. Schieber, Maria Vegega

United States Public Health Resources

EXECUTIVE SUMMARY
Motor vehicle crashes are associated with one of every five deaths among children 1 to 14 years of age in the United States, and pedestrian injuries account for a third of them. Compared with occupant injuries, pedestrian injuries are more severe; death is five times more likely to occur among those injured. In 1999, 533 child pedestrians were killed, and at least 30,000 children were nonfatally injured in traffic. Another 200 were killed in non-traffic areas, including driveways, sidewalks, and parking lots. Traumatic brain injury accounts for more than half the fatalities.
Dr. Schieber noted that the decline …

Building Jefferson's Future, Douglas J. Macmaster Jr., Paul C. Brucker

Thomas Jefferson University Administrative Documents and Reports

2002 Annual report of Thomas Jefferson University.

Jefferson Medical College Annual Report, 2002, Thomas J. Nasca

Jefferson Medical College Administrative Documents and Reports

No abstract provided.

Challenges, Strategies, And Tools For Research Scientists: Using Web-Based Information Resources, Danielle Bodrero Hoggan

E-JASL: Electronic Journal of Academic and Special Librarianship (1999-2009, Volumes 1-10)

Scientists face many challenges in harnessing web-based resources. Information overload, misinformation, fees, poorly designed navigation, and loss of browsability all hamper the scientist searcher. In addition, many scientists rely on only one or two databases and often miss unique information that is available through other sources. Librarians can team up with scientists to develop strategies to overcome the challenges of web-based information. For example, a librarian can teach effective information seeking techniques, including how to use controlled vocabularies, how to evaluate information on the web, and how to complement web-based resources with print resources. Librarians can also help scientists to …

A Mutation In The Latency-Related Gene Of Bovine Herpesvirus 1 Disrupts The Latency Reactivation Cycle In Calves, Melissa Inman, Luciane Lovato, Alan R. Doster, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

Bovine herpesvirus 1 (BHV-1) is an important pathogen of cattle, and infection is usually initiated via the ocular or nasal cavity. Following acute infection, the primary site for BHV-1 latency is the sensory neuron. Reactivation from latency occurs sporadically, resulting in virus shedding and transmission to uninfected cattle. The only abundant viral transcript expressed during latency is the latency-related (LR) RNA, suggesting that it mediates some aspect of latency. An LR mutant was constructed by inserting three stop codons near the beginning of the LR-RNA, suggesting that expression of LR proteins would be altered. The LR mutant grew with wild-type …

Identification Of The Vibrio Cholerae Enterobactin Receptors Vcta And Irga: Irga Is Not Required For Virulence, Alexandra R. Mey, Elizabeth E. Wyckoff, Amanda G. Oglesby, Eva Rab, Ronald K. Taylor, Shelley M. Payne

Dartmouth Scholarship

The gram-negative enteric pathogen Vibrio cholerae requires iron for growth. V. cholerae has multiple iron acquisition systems, including utilization of heme and hemoglobin, synthesis and transport of the catechol siderophore vibriobactin, and transport of several siderophores that it does not itself make. One siderophore that V. cholerae transports, but does not make, is enterobactin. Enterobactin transport requires TonB and is independent of the vibriobactin receptor ViuA. In this study, two candidate enterobactin receptor genes, irgA (VC0475) and vctA (VCA0232), were identified by analysis of the V. cholerae genomic sequence. A single mutation in either of these genes did not significantly …

Phylogenetic Analysis Of Brazilian Bovine Viral Diarrhea Virus Type 2 (Bvdv-2) Isolates: Evidence For A Subgenotype Within Bvdv-2, Eduardo F. Flores, Julia F. Ridpath, Rudi Weiblen, Fernanda S. F. Vogel, Laura H.V.G. Gil

School of Veterinary and Biomedical Sciences: Faculty Publications

Phylogenetic analysis divides bovine viral diarrhea viruses (BVDV) into two different genotypes (BVDV1 and BVDV2). BVDV1 strains have been further subdivided into two to 11 subgenotypes. Phylogenetic analysis of BVDV2 isolates, however, has not been able to identify discrete subgenotypes. In this study, we identified six South American BVDV2 strains and one North American BVDV2 strain that cluster to a separate genetic group within BVDV2, thus representing a distinct subgenotype. The 5’ untranslated region (UTR) sequence homology between these six strains and other BVDV2 from North America, Europe and Asia (81.7%) is lower than the homology used to segregate BVDV1 …

Research News: 2002, No. 2, University Of Mississippi. School Of Pharmacy

Research News: Grants and Publications (2000-2014)

Grants, publications, technology transfer, special announcements

Hatch-Waxman, Generics, And Patents: Balancing Prescription Drug Innovation, Competition, And Affordability, Robin J. Strongin

National Health Policy Forum

This paper explores the complex connections among intellectual property protection, competition, and access to affordable prescription drug products. It focuses on several provisions of the Drug Price Competition and Patent Term Restoration Act of 1984 (Hatch-Waxman) and discusses the debate swirling around its reform. An overview of landmark intellectual property laws and a description of the generic drug approval process are also included.

Would Smokers With Schizophrenia Benefit From A More Flexible Approach To Smoking Treatment?, Dennis E. Mcchargue, Susy B. Gulliver, Brian Hitsman

Department of Psychology: Faculty Publications

We evaluated literature that addresses the notion that flexible smoking treatment approaches are warranted for smokers with a diagnosis of schizophrenia. Understanding the biological and psychological mechanisms that increase the likelihood of smoking and decrease the motivation to quit for these individuals is addressed within the framework of a neurobiological model. We provide a brief overview of the limited smoking cessation treatment literature for patients with schizophrenia and compare abstinence-focused versus reduction-focused treatment modalities. The potential utility of the reduction-focused approach to tobacco treatment for these smokers is evaluated. Suggestions for future research to address the utility and efficacy of …

Will The Nation Be Ready For The Next Bioterrorism Attack? Mending Gaps In The Public Health Infrastructure, Eileen Salinsky

National Health Policy Forum

This paper provides an overview of critical weaknesses in public health preparedness capabilities and discusses policy initiatives to address these shortcomings. It examines developmental needs related to communication and coordination, information systems, laboratories, the development and distribution of vaccines and other countermeasures, emergency medical preparedness and response, and the public health workforce. The paper summarizes the status of federal and state plans to respond to these developmental needs and touches on the challenges likely to emerge as these plans are implemented.

Spin Trapping Pharmaceutical Compositions And Methods For Use Thereof, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Spin trapping compositions in general have now been discovered to be effective in treating a variety of disorders, including disorders such as those arising from ischemia, infection, inflammation, exposure to radiation or cytotoxic compounds, not just of the central and peripheral nervous systems but of peripheral organ disease having a wide variety of etiologies. In the preferred embodiment, the compositions for treating tissue damage from ischemia contain PBN, or active derivatives thereof, in a suitable pharmaceutical carrier for intravenous, oral, topical, or nasal/pulmonary administration. Other preferred spin-trapping agents include 5,5-dimethyl pyrroline N-oxide (DMPO), α-(4-pyridyl-1-oxide)-N-tert-butylnitrone (POBN), and (TEMPO) and spin-trapping derivatives …

Use Of An Anaerobic Chamber Environment For The Assay Of Endogenous Cellular Protein-Tyrosine Phosphatase Activities., Li Zhu, Barry Goldstein

Department of Medicine Faculty Papers

Protein-tyrosine phosphatases (PTPases) have a catalytic cysteine residue whose reduced state is integral to the reaction mechanism. Since exposure to air can artifactually oxidize this highly reactive thiol, PTPase assays have typically used potent reducing agents to reactivate the enzymes present; however, this approach does not allow for the measurement of the endogenous PTPase activity directly isolated from the in vivo cellular environment. Here we provide a method for using an anaerobic chamber to preserve the activity of the total PTPase complement in a tissue lysate or of an immunoprecipitated PTPase homolog to characterize their endogenous activation state. Comparison with …

Average Wholesale Price For Prescription Drugs: Is There A More Appropriate Pricing Mechanism?, Dawn Gencarelli

National Health Policy Forum

This paper defines the average wholesale price (AWP), an important benchmark for prescription drug pricing and reimbursement. The paper briefly explains the AWP's various uses in the pricing of prescription drugs, highlights some of the problems that have emerged as a result of the way it is reported and used, and explores some of the possibilities for reform. The paper also contains a glossary of commonly used terms, as well as an appendix that lists the state Medicaid reimbursement formulas.

What's Happening: June 5, 2002, Maine Medical Center

What's Happening

No abstract provided.

Commencement Program 2002, Loma Linda University

Commencement Programs

CONTENTS

2 | 2002 Events of Commencement

3 | The Academic Procession

4 | Significance of Academic Regalia

5 | The Speakers

11 | The University Honorees

18 | The School Honorees

27 | The Programs

• School of Medicine, 28
• School of Dentistry, 35
• Graduate School, 43
• School of Nursing, 53
• School of Allied Health Professions - Physical Therapy, 58
• School of Allied Health Professions, 66
• School of Public Health, 75

Oncolog, Volume 47, Number 06, June 2002, Kate O'Suilleabhain, Dawn Chalaire, Shellie M. Scott Bs

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Drug Development Program Paves the Way for FDA Approval of New Agents
• Pediatric New Agents Working Group Advances the Study of Novel Treatments in Young Patients
• DiaLog: Patients and Physicians: Partners in Health Care, by Shellie M. Scott, BS, Physician Assistant, Department of Urology
• House Call: Taking a More Active Role in Your Own Health Care
• As Population of Cancer Survivors Grows, Studies of Long-Term Health Effects Become More Critical, Researchers Say

The Clinical Irrelevance And Scientific Invalidity Of The "Minority" Notion: Deleting It From The Social Science Vocabulary, Doris Wilkinson

The Journal of Sociology & Social Welfare

A systematic socio-linguistic and historical analysis of the minority label reveals its multiple irregularities and imperfections. These encompass a misleading array of vastly dissimilar nationality or group designations and the erroneous comparison of behaviors and life styles with racial status. As it is currently applied in U.S. political culture and in a variety of disciplines including sociology and social work, the concept has virtually no substantive meaning nor reality-linked usefulness. A thorough appraisal of the consequences of the perpetual reliance on the notion demonstrates that it eradicates ethnic cultural diversity and ignores historical antecedents and the "lived" experiences of oppressed …

Protein-Protein Interactions And Muscle Cell Signaling Via Syntrophin, Shilpa A. Oak

Theses and Dissertations (ETD)

Absence of dystrophin results in Duchenne muscular dystrophy (DMD), a lethal neuromuscular d isorder that afflicts 1 in 3500 live male births. In the sarcolemma, dystrophin is associated with a complex of proteins and glycoproteins, known as the dystrophin glycoprotein complex. The DGC constituents are dystrophin, a-dys troglycan, b-dystroglycan, syntrophin, a-sarcoglycan, b-sarcoglycan, g-sarcoglycan, d-sarcoglycan, and sarcospan. Not al l of these are single protein species. The syntrophins consists of a group of three homologous proteins composed of acidic (a) and basic (b) components. Syntrophins are known to self-associate to form oligomers.

In this dissertation, syntrophin's oligomerization and its interactions with …

Inducible Gene Expression In Cell Cultures And In Microencapsulated Cells, Yong Yu

Loma Linda University Electronic Theses, Dissertations & Projects

The mifepristone-regulated transcriptional activation system provides a means to exogenously control gene expression in transformed mammalian cells in a temporal and spatial fashion. Such a promoter activation system consists of three components: The first of these is a steroidal inducer drug, mifepristone. This drug binds to the second component, a chimeric transcription factor complex, consisting of the mutant human progesterone receptor fused to the yeast GAL4 DNA-binding domain and the Herpes simplex virus protein VP 16 activation domain. The third component is a synthetic promoter, consisting of a series of GAL4 recognition sequences upstream of the adenovirus major late E1B …

The Role Of Psychologists In Primary Care: An Integrative Curriculum, Gary Charles Hawley

Loma Linda University Electronic Theses, Dissertations & Projects

Psychologists have been service providers in the health care sector for many years. They are consistently recognized as valued members of health care teams but are not frequently included as primary care providers. Integrated primary care services that include psychologists are a positive step toward achieving a comprehensive model of patient care. The biopsychosocial model is suggested to supplant the current biomedical model for health and wellness conceptualization. Psychologists are trained in the dynamic interplay between biological, psychological, and social domains. However, education at the graduate level for psychologists working specifically in primary care has not been well conceptualized, developed …

Effect Of Electrode Size, Shape, And Placement On Electrical Current And Subject Comfort During Electrical Stimulation, Bonnie J. Forrester

Loma Linda University Electronic Theses, Dissertations & Projects

Six healthy subjects were studied to determine the optimal size, shape and placement of stimulating electrodes during the application of electrical stimulation (ES) to the biceps, quadriceps, and tibialis anterior muscles. Subjects were recruited to allow for diversity in age, sex, and skin pigmentation. Subjects sat in a custom designed multi-positional chair, which allowed precise positioning of each extremity. After determining the maximal voluntary contraction (MVC) of the muscle and careful determination of the motor point, ES, with a biphasic square wave of 300 ms duration and a frequency of 30 Hz, was used to bring the muscle to 10% …

The Relationship Between The Osteonal Cement Line And Bone Strength, Avery Kazuhiro Egerer

Loma Linda University Electronic Theses, Dissertations & Projects

Bone includes many structural and chemical components which provide both flexibility and strength. One such structure is the cement line, a 1-5 μm-thin structure located primarily in compact bone. Past research has correlated the pathological condition of “shin splints” with the micro-damage of bone, which often follows cement lines. It has been suggested that cement lines have rather paradoxical properties. Upon fatigue fracture of bone, microcracks often travel along cement lines and become trapped. This trapping and subsequent dispersion of energy have been hypothesized to prevent a complete fracture from occurring, extending bone life. Cement lines have been implicated in …

Effect Of Added Mass On Human Unipedal Hopping, Gary P. Austin, Gladys E. Garrett, David Tiberio

All PTHMS Faculty Publications

Although hopping is considered a children's activity, it can be used to provide insight into the neuromuscular and biomechanical performance of adults. This study investigated whether mass added during unipedal hopping altered the vertical stiffness, hopping period, and angular kinematics of the lower exteremity of adults. Measures of two-dimensional kinematics and vertical force were made from 10 healthy men during hopping at a preferred period under three conditions: Body Mass, Body Mass +10%, and Body Mass +20%. Adding mass significantly increased hopping period and hip flexion without significantly affecting vertical stiffness, ankle dorsiflexion, or knee flexion. Overall, the findings agreed …

Effect Of Frequency On Human Unipedal Hopping, Gary P. Austin, David Tiberio, Gladys E. Garrett

All PTHMS Faculty Publications

All mature forms of locomotion involve periods of unilateral stance. Unipedal hopping may provide useful information about the neuromuscular and biomechanical capabilities of a single lower extremity in adults. This study investigated whether hopping influenced vertical stiffness and lower extremity angular kinematics during human unipedal hopping. Vertical force and two-dimensional kinematics were measured in 10 healthy males hopping at three frequencies: preferred, +20%, and -20%. At +20%, compared to preferred, vertical stiffness increased 55% as hip flexion, knee flexion, and ankle dorsiflexion decreased, while at -20%, vertical stiffness decreased 39.4% as hip flexion, knee flexion, and ankle dorsiflexion increased. As …

Jefferson Alumni Bulletin - Volume 51, Number 3, June 2002

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume 51, Number 3, June 2002 New Appointments; Page 4 Gift of Health: Herbert Kean Endows Chair in Otolaryngology; Page 6 Investigations: Zebrafish: A Potential Community Outreach Program; Page 7 Hospital Appointments; Page 10 Match Day; Page 12 Profile: Urologic Surgery’s “Real Deal”; Page 14 Profile: When Terror Hit the Pentagon, Stephen Frost’s Reaction Was: Tend the Injured; Page 16 Profile: Searching for the Cause of the Rash That’s Itching Pupils; Page 17 In Memoriam; Page 18 Class Notes; Page 19 Building on Knowledge of Angiogenesis, Invention Provides Hope to the Obese; Page 22 Griffith Heads …

The Disease Model Of Alcoholism: A Kuhnian Paradigm, Brian E. Bride, Larry Nackerud

The Journal of Sociology & Social Welfare

Despite the fact that the disease model of alcoholism has lost its status as paradigm in international circles, the alcoholism research and treatment community in the United States maintains steadfast allegiance to the tenets of the disease model. The disease model and the related treatment goal of abstinence continue to overwhelmingly dominate the treatment of alcoholism in the U.S. Critics have suggested that financial and political motives have served to maintain the dominance of the disease model, despite findings that violate its basic tenets. This paper presents an alternative explanation of the reluctance of the alcoholism treatment community to relinquish …

Stretch-Induced Calcium Release In Smooth Muscle., Guangju Ji, Robert J Barsotti, Morris E Feldman, Michael I Kotlikoff

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Smooth muscle cells undergo substantial increases in length, passively stretching during increases in intraluminal pressure in vessels and hollow organs. Active contractile responses to counteract increased transmural pressure were first described almost a century ago (Bayliss, 1902) and several mechanisms have been advanced to explain this phenomenon. We report here that elongation of smooth muscle cells results in ryanodine receptor-mediated Ca(2+) release in individual myocytes. Mechanical elongation of isolated, single urinary bladder myocytes to approximately 120% of slack length (DeltaL = 20) evoked Ca(2+) release from intracellular stores in the form of single Ca(2+) sparks and propagated Ca(2+) waves. Ca(2+) …