Digital Commons Network^™

The Incidence Of Some Intestinal Protozoa: Entamoeba Histolytica, Blastocystis Hominis And Giardia Lamblia Among Iraqi Individuals At Baghdad Province, Amani M. Jasim, Rabia A. Aboud, Mohamed Q. Al-Aybi

BioMed Visions Journal

This study investigates incidence of Entamoeba histolytica, Blastocystis hominis and Giardia lamblia at Baghdad province during during the months of 2024. Samples were collected from patients admitted Baghdad hospitals during a period of January to the end of December 2024 and examine by Macroscopic Examination by direct wet mounts and Concentration Methods using formalin-ethyl acetate sedimentation or zinc sulfate flotation to concentrate ova/cysts analyzed .The findings indicate that no significant differences among study groups individuals infected with Entamoeba histolytica out of 222,133 individulas infected with Entamoeba histolytica (32%) females most frequently infected than males (27%).Giardia lambilia according to gender …

Cytotoxicity Of Dimethyl Sulphoxide On Viability Of Peripheral Hematopoietic Stem Cells, Rana Nidhamaldeen Al-Nuri, Francesco Ipsevich, Lazim Subhi Sheet

BioMed Visions Journal

Background: Hematopoietic stem cells (HSC) are cells that can differentiate according to the tissue they are lying in. The transplantation of such cells is either autologous or allogeneic. Autologous storage is required until the patient finishes his intensive chemotherapy. Whilst allogenic storage is required until finding the suitable matched recipient for this cellular therapy. Storage is in deep frozen state (–80° C) with cryoprotectant compound. Dimethyl sulphoxide (DMSO) has been used as cryoprotectant due to its electrophilic property that makes H-bond between DMSO and H₂O, which is 2.6 times stronger than the H bond between two water molecules. …

Evaluation The Attitudes Toward Prevention Of Communicable Diseases On Health Care Workers At Al-Sadr Hospital In Iraq's Najaf Governorate, Ahmed Ali Mohammed Alshamarti, Wisam Abdul Ameer Ali Farid, Atheer Kadhim Ibadi, Sabreen Ali Hassoni

BioMed Visions Journal

Background: Communicable diseases are responsible for a heavy burden on human health. Health workers were the front line in preventing these diseases. Wrong or positive attitudes of health workers can reflect negatively or positively on infection control efforts. The primary objective of study evaluating attitudes levels between health care workers towards transferable diseases. The secondary objective, assessing association with social-demographic characteristics of health workers. Materials and Methods: The data from Al-Sadr Hospital, by use a frequency study started from the 1^st of December 2021 to the 30^th of May in 2022. The sample from 384 health care workers …

Evaluation Of Antifungal Properties Of Shiitake And The Effects Of Its Extracts On Some Pathogenic Fungi, Asal Faiz Hameed Aldabbgh, Abdalkarim S. Hasan Alnuaimi, Inaam Jasim Mohamad

BioMed Visions Journal

The present study aims to investigate the inhibitory effect of shiitake mushrooms on some common fungi found in the soil of Mosul City. The fungal extract from Shiitake was prepared using ethanol or water. Different concentrations of the extract were prepared to analyze the antifungal properties of the mushroom by first making a stock solution and then adding specific amounts to the plates containing (Potato Dextrose Agar) PDA medium to achieve the desired concentrations. The active components found in Shiitake were pinpointed through the use of HPLC. The findings revealed how the aqueous extract of Shiitake affected Trichoderma sp. Penicillium …

Deciphering The Association Of Fasting Blood Glucose With Gamma-Glutamyl Transferase And Uric Acid: A Cross-Sectional Study In A Tertiary Care Hospital In South India, Anbalagan Anithasri, Rajagambeeram Reeta, Velmurugan Hasini

Sultan Qaboos University Medical Journal

Objectives: Fasting hyperglycaemia (FHG) in insulin resistance is due to oxidative stress wherein gamma-glutamyl transferase (GGT) and uric acid (UA) are known to impair insulin secretion from pancreatic beta cells due to their pro-oxidant action and their role in metabolism of antioxidant glutathione. This study aims to determine the association of GGT and UA with FHG and its role in predicting the onset of prediabetes. Methods: This cross-sectional study was conducted in Government Villupuram Medical College, Villupuram, India, from July to December 2023. Individuals in the age range of 25–65 years attending the master health check-up clinic were included. …

The Role Of Mental Health In Postoperative Complications: A Literature Review, Kayla Monet Alwahhamy, Abbas Rasoul Alwahhamy

Iraqi National Journal of Medicine

Background: Currently, it is not standard practice to screen all surgical patients both pre- and postoperatively for either a prior history of mental health disorders (MHD) or active symptoms of MHD at the time of surgery. This is despite growing evidence that MHDs may impact wound healing and are recognized as a mortality risk factor in many patients. Aim: This review aims to evaluate existing literature examining mental health (MH) in surgical patients, assess whether there is a relationship between MHDs and postoperative complication rates, and determine whether outcomes differ based on the timing of MHD manifestation (pre- …

Antimicrobial Susceptibility And Prevalence Of Multidrug-Resistant Klebsiella Pneumoniae In Pediatric Patients In Karbala, Iraq: A Two-Year Retrospective Study, Hussein Abd Ali Mohammed Sadeq Al Her, Al-Shalah Al-Shalah, Saif A.J. Abdulrahman, Ekhlas Abdulameer Hameed Alazzawi, Noor Hussein Abdulrahman

Iraqi National Journal of Medicine

Background: Klebsiella pneumoniae is a major pediatric pathogen causing infections such as urinary tract infections, pneumonia, neonatal sepsis, and meningitis, with heightened risk in children due to immune immaturity and hospital exposure. Aim: This study aimed to retrospectively analyze the prevalence and patterns of antibiotic resistance in Klebsiella pneumoniae isolated from various clinical samples in pediatric cases at Karbala Children's Hospital from January 1, 2022 to December 31, 2023. Methods: This retrospective study examined 68 pediatric K. pneumoniae infection cases at Karbala Children's Hospital in Iraq from 2022 to 2023. Clinical samples, patient demographics, and antibiotic susceptibility were …

A Systematic Literature Review Of Cvid Reveals Pervasive Detrimental Noninfectious Manifestations, Robert B Lindell, Samir U Sayed, Jose S Campos Duran, Sydney A Sheetz, Apoorva Babu, Montana S Knight, Andrea A Mauracher, Ceire A Hay, Peyton E Conrey, Julie C Fitzgerald, Nadir Yehya, Stephen T Famularo, Teresa Arroyo, Richard Tustin, Hossein Fazelinia, Edward M Behrens, David T Teachey, Lisa R Forbes Satter, Alexandra F Freeman, Jenna Re Bergerson, Steven M Holland, Jennifer W Leiding, Scott L Weiss, Mark W Hall, Deanne M Taylor, Rui Feng, E John Wherry, Nuala J Meyer, Sarah E Henrickson

Faculty, Staff and Students Publications

BACKGROUND

Sepsis is a leading cause of morbidity and mortality in critically ill children, yet heterogeneous immune responses complicate the development of targeted therapies and the host immune factors driving sepsis pathobiology remain unclear.

METHODS

We integrated deep immune phenotyping, plasma proteomics, single-cell transcriptomics, and phosphoflow cytometry in a prospective cohort of 88 critically ill children to elucidate the mechanisms underlying immune heterogeneity.

RESULTS

Unsupervised clustering of plasma cytokines identified 3 immunologic subgroups, including a high-severity group (“Group C”) characterized by hypercytokinemia driven by IL-6 and IFN-γ. Group C exhibited distinct alterations in immune cell frequency and activation, with a …

Comparative Analysis Of Traditional And Deep Learning Time Series Architectures For Influenza A Infectious Disease Forecasting, Edmund Fosu Agyemang, Hansapani Rodrigo, Vincent Agbenyeavu

School of Mathematical & Statistical Sciences Faculty Publications

Influenza A remains a major cause of respiratory mortality worldwide, motivating accurate forecasting to support timely preparedness and resource allocation. This study presents a comparative evaluation of two traditional seasonal time series baselines, ARIMA and Holt–Winters exponential smoothing (ETS), and six deep learning (DL) architectures (Simple RNN, LSTM, GRU, BiLSTM, BiGRU, and a Transformer) for forecasting monthly Influenza A case counts in the United States. Data from January 2009 to December 2023 were analyzed, using January 2009 to December 2022 for training and January 2023 to December 2023 for out-of-sample testing. Models were tuned using a validation split and assessed …

Depressive Symptoms And Functional Disability Among Older Adults In Nakhon Ratchasima Province, Thailand: A Cross-Sectional Population-Based Study, Jiranya Bureemas, Atthawit Singsalasang

Journal of Health Research

Background: Depressive symptoms have been associated with activities of daily living (ADL) disability; however, evidence among Thai older adults remains limited and inconsistent. This study investigates the association between depressive symptoms and ADL disability in older Thai adults.

Methods: A cross-sectional analytic study was conducted among 312 older adults in Nakhon Ratchasima, Thailand, who were selected using a multistage sampling method. Data were collected between April and July 2023 using structured questionnaires covering demographic and environmental variables. Depressive symptoms were assessed using the 15-item Geriatric Depression Scale. ADL disability was measured using the Barthel and Chula ADL Indices. Multiple logistic …

Fish Tissue Digestion And Microplastic Polymer Identification Protocol Using Open-Source Ftir Database, Shawn L. Kissinger, Vick-Ariel Privert, Jason Bystriansky, Kyle A. Grice

DePaul Discoveries

Microplastic (MP) contamination in aquatic ecosystems poses significant concerns for environmental and public health, as seafood represents a critical food source worldwide. Despite increasing evidence of MP presence in marine organisms, efficient and accessible detection methods remain essential for characterizing contamination patterns and informing regulatory frameworks. This study extracted MPs from brain, gill, intestine, liver, and muscle tissues of gilt-head bream (Sparus aurata) and European sea bass (Dicentrarchus labrax), two commercially important species from the Gulf of Cádiz, Spain, using a NaOH–HNO₃ chemical digestion protocol. Isolated particles were characterized by Fourier Transform Infrared (FTIR) spectroscopy, with …

Crystal Structural Analysis Of Medieval Human Bones Using Wide-Angle X-Ray Scattering, Selly Altangerel, Leslie Gracia

DePaul Discoveries

Female human second metacarpal (mc2) bones from a medieval cemetery at Wharram Percy, England, were studied using high-energy Wide-Angle X-ray Scattering (WAXS) at beamline 1-ID of the Advanced Photon Source at Argonne National Laboratory. The age-at-death of 33 samples was determined from molar wear and classified into 3 groups:  18-30, 30-50, and 50+ years old.  Rietveld refinements of the WAXS data were performed to obtain lattice parameters of the hexagonal carbonated apatite phase (cAp). Individual fittings for cAp peaks 00.2, 00.4, and 31.0 were performed to obtain their widths and correlate them to collagen retention. For the three samples described …

Rethinking Vaginal Microbiome Resilience: A Conceptual Multi-Omic Framework, Brittnee Cagle-White, Rob E. Carpenter, Alaina Vincent, Ellen Kominek, Andrew Krouse

Human Resource Development Faculty Publications and Presentations

The vaginal microbiome is often interpreted through static taxonomic patterns. Yet microbial composition alone does not explain why some communities resist perturbation, recover after disruption, or transition toward dysbiosis. This narrative review synthesizes evidence that vaginal microbiome stability is shaped by endocrine phase, epithelial substrate availability, microbial functional capacity, mucosal tone and candidate host modifiers. High-estrogen states, particularly pregnancy, are associated with epithelial maturation, glycogen accumulation, low vaginal pH, and Lactobacillus-dominant communities, whereas postpartum, lactational, menopausal, and other hypoestrogenic states are associated with reduced epithelial support and increased vulnerability to diverse anaerobe-rich configurations. We review the linking of the estrogen–glycogen–Lactobacillus …

Testing Elicitors Of Homologous Jadr2 Proteins To Regulate Natural Product Production, Carzon J. Williams, Emilee A. Patterson, Allison S. Walker

SPARK Symposium Presentations

The growing threat of antimicrobial resistance (AMR) has and will contribute to global economic and public health concerns in the foreseeable future leading into 2050. As mortality rates derived from AMR are projected to reach 10 million if no viable solution is found to combat it through hastened drug discovery. The use of natural products to mitigate AMRs effects is viable as more than 50% of FDA approved drugs are natural products. These natural products are synthesized by biosynthetic gene clusters (BGC), found in bacteria with a regulatory protein not allowing transcription until unbound . Current methods of eliciting the …

The Exploration Of The Antidiabetic Potentialities Of Bottle Gourd (Lagenaria Siceraria) Fruits Through In Vivo, In Vitro And In Silico Approaches, Arifa Sultana, Fahima Aktar, Fabiha Noushin, Mariam Wahed, Jakir Ahmed Chowdhury, Abu Asad Chowdhury, Shaila Kabir, Md. Shah Amran

Pharmaceutical Sciences and Research

Due to the ineffectiveness, side effects, and high cost of conventional drugs, medicinal plants grabbed the attention to treat diabetes, which has been a global health concern nowadays. Therefore, this study aims to investigate the antidiabetic potentialities of bottle gourd (Lagenaria siceraria) fruits in in vivo, in vitro, and in silico methods. For the in vivo assessment, alloxan-induced diabetic rats were fed food mixed with bottle gourd powder for 21 days. For the in vitro assessment, the alpha-amylase inhibitory assay was used to determine the antidiabetic properties of an ethanolic extract of L. siceraria. For the …

Dabrafenib-Induced Cutaneous Eruptions In A Patient With Langerhans Cell Histiocytosis, Jaanvi Mehta, Julianna Tolotta, Eleanor Matthews, Daniel Joffe, Safiyyah Bhatti, Lauren Banner, Jenna Mandel, Molly Wallace, Timothy G. Webster, Jason B. Lee, Neda Nikbakht

Department of Dermatology and Cutaneous Biology Faculty Papers

Langerhans cell histiocytosis (LCH) is a rare malignancy marked by clonal proliferation of Langerhans cells, with BRAF V600E mutations identified in over 50% of the cases. BRAF inhibitors (BRAFi), such as dabrafenib, have shown efficacy in treating BRAF V600E-mutant LCH. However, BRAFi therapy is associated with cutaneous adverse effects, including the development of new melanocytic nevi, verrucae, and keratinocyte carcinoma (KC). This case report describes a 78-year-old woman with BRAF V600E-mutant LCH who developed multiple dermatologic side effects following dabrafenib salvage therapy. Seven weeks into treatment, the patient presented with eruptive palmoplantar nevi, verrucae, and a basal cell carcinoma (BCC). …

Combining Menin And Mek Inhibition To Target Poor Prognosis Kmt2a-Rearranged Ras Pathway-Mutant Acute Myeloid Leukemia., Nastassja Scheidegger, Constanze Schneider, Gabriela Alexe, Yi-Cheng Wang, Todd A. Alonzo, Allen Basanthakumar, Wallace A. Bourgeois, Julia Dudkiewicz-Garbicz, Delan Khalid, Lucy A. Merickel, Jennifer A. Perry, Rhonda E. Ries, Silvi Salhotra, Audrey Taillon, Alan S. Gamis, Richard Aplenc, Marian H. Harris, Mark Wunderlich, Scott A. Armstrong, Jessica A. Pollard, Soheil Meshinchi, Yana Pikman, Kimberly Stegmaier

Manuscripts, Articles, Book Chapters and Other Papers

KMT2A-rearranged (KMT2A-r) acute leukemias are especially prevalent in the pediatric population. KMT2A-fusion proteins drive leukemogenic gene expression through an interaction with a chromatin complex that includes the scaffold protein menin, giving rise to aggressive acute leukemias. RAS pathway mutations are also common in pediatric leukemia. In a cohort of 1750 patients enrolled on Children's Oncology Group (COG) trials, we identified RAS pathway mutations in 43% of acute myeloid leukemia (AML) cases. The presence of RAS pathway mutations in KMT2A-r AML was associated with a lower complete remission rate, poor event-free survival and overall survival (OS), and early relapses. Given the …

Comments Re: Regulation For Federal Financial Assistance, Fred D. Ledley, Edward Zhou, Brian C. Fox

CISI Publication

This comment focuses on the proposed modifications to §200.205 “Federal Agency Merit Review of Proposals” and §200.340 “Termination and suspension” of Title 2 of the Code of Federal Regulations. We argue that the pre-issuance review, discretionary termination provisions, and other constraints of federal research support that would be established under this proposal create impediments to the scientifically-driven process of discovery and innovation that has long provided the foundation for advances in American prosperity, influence, health, and wellbeing. Our comments focus specifically on federal support for biomedical research by the National Institutes of Health (NIH) for the purpose of advancing healthcare …

Metabolic Syndrome Is Associated With Increased Mortality In Patients With Breast Or Prostate Cancer, Jessica P Hwang, Ning Zhang, Mercy W Misoi, Sabhi Gull, Zayd A Razouki, Justin R Gregg, Natalia I Heredia, Sharon H Giordano

Faculty, Staff and Student Publications

We investigated the association of metabolic syndrome (MetS) with mortality in patients with breast and prostate cancer. Breast and prostate cancer cohorts were created retrospectively using the SEER-Medicare database. Patients with first primary breast or prostate cancer diagnosed in 2008-2019 were identified using ICD-O-3 site and histology codes. Among those, patients with MetS were identified using ICD-9/10-CM codes, CPT/HCPCS codes, and prescription drug use from Medicare claims files. We defined continuous enrollment from 12 months before through 12 months after diagnosis, exposure during the first 12 months after diagnosis, and survival follow-up starting 12 months after diagnosis. We used multivariable …

Isolated Transverse Colon Perforation During Corticosteroid Tapering In Quiescent Systemic Lupus Erythematosus: A Histopathology-Supported Diagnosis Of Exclusion, Ridwan A. Lawal, Nestor Malaga, Nida Asif, Fatimah Bello, Juliana Yang

School of Medicine Publications

Gastrointestinal perforation in systemic lupus erythematosus (SLE) is uncommon but potentially fatal, and attribution is clinically consequential because perforation may reflect lupus enteritis with mesenteric vasculitis, infection, diverticular or stercoral disease, malignancy, inflammatory bowel disease (IBD), medication-related injury, or a combination of mechanisms. Corticosteroid-associated perforation is therefore best treated as a diagnosis of exclusion rather than as an isolated novel observation. We report a 62-year-old woman with SLE who developed sudden severe right-sided abdominal pain, nausea, vomiting, leukocytosis, lactic acidosis, and radiographic pneumoperitoneum while tapering prednisone from 60 mg/day to 10 mg/day over three months, with 10 mg/day documented at …

Slc Transporter-Mediated Functional Imaging In Cancer Diagnosis, Lumeng Zhang, Jun He

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Functional imaging has become an important approach for evaluating tumor physiology in vivo beyond morphologic assessment. Radiotracers used for cancer imaging are designed to mimic endogenous substrates or substrate analogues, and their accumulation can depend on membrane transport, intracellular metabolism, and clearance from normal tissues. Specifically, SLC transporters contribute to tracer uptake and signal formation, linking transporter activity with measurable imaging signals in cancer. While [18F]FDG PET/CT remains the most widely used example of transporter-associated metabolic imaging, SLC transporter-mediated imaging strategies have been developed to assess amino acid transport, sodium-dependent glucose uptake, redox metabolism, lactate exchange, nucleoside metabolism, choline metabolism, …

Depression And Anxiety In Pulmonary Hypertension Associated With Congenital Heart Disease: Pathophysiology And Clinical Implications Of The Heart–Brain Axis, Nicodemus N. Triatmojo, Valerinna Y.S. Putri

Journal of the Saudi Heart Association

Pulmonary hypertension associated with congenital heart disease or PH-CHD is an increasingly prevalent disorder in modern cardiology. It is characterized by progressive pulmonary vascular remodeling, chronic right ventricular (RV) pressure overload, and abnormal cardiopulmonary hemodynamic. Due to advances in congenital cardiology and treatments for pulmonary hypertension, survival rates have increased. As a result, the focus has switched to long-term functional status and quality of life. Depression and anxiety are currently recognized as prevalent and clinically significant manifestations in PH-CHD; nonetheless, they remain underdiagnosed and undertreated within cardiovascular care frameworks.

More study shows the disease's severity or symptom count cannot explain …

Feasibility Study Of An Artificial Intelligence Chatbot-Powered Cognitive-Behavioral Lifestyle Modification Program, Evans Forman, Charlotte Hagerman, Asher Hong, Zhuoran Huang, Hannah Mccausland, Jasmine Sun, Lauren Taylor, Meghan Butryn, Preetha Chatterjee, Ramtin Ehsani, Nawal Syed

Department of Family & Community Medicine Faculty Papers

Background: Approximately 2 billion adults seek lifestyle modification to improve their health and well-being. However, because of cost and access barriers, only a tiny fraction receive gold-standard lifestyle modification programs led by trained coaches. Digital programs without human coaches are more disseminable but have limited efficacy. Recent advances in large language model (LLM) AI chatbots have the potential to revolutionize digital programs by emulating human coaches, offering a safe, low-cost, and scalable lifestyle modification intervention. Yet, no studies have developed and tested such a program. Purpose: This study aims to evaluate the feasibility, safety, and user engagement of a new …

A Phase Ii Trial Of Defactinib Combined With Avutometinib In Patients With Metastatic Uveal Melanoma, Rino S. Seedor, Mizue Terai, Sergei A. Koshkin, Andrew E. Aplin, Marlana Orloff, Erin Sharpe-Mills, Madeleine Naccarato, Aurora Mills, Alfredo A. Molinolo, J. Silvio Gutkind, Takami Sato

Kimmel Cancer Center Faculty Papers

Background: Treatment options are limited, and outcomes remain poor for patients with metastatic uveal melanoma (MUM). We conducted an investigator-initiated, prospective, single-arm, single-institution, phase II study evaluating the combination of an FAK inhibitor (defactinib) with a RAF/MEK inhibitor (avutometinib) for the treatment of MUM. Methods: From February 2021 through January 2023, 12 patients with MUM were treated with the combination of defactinib and avutometinib. Defactinib was given 200 mg twice daily, and avutometinib was given 3.2 mg twice a week. Both drugs were given for 3 weeks on and 1 week off (28-day cycle). Disease control rate was the primary …

Impact Of Social Media-Driven Feeding Practices On The Gut Microbiome Of Captive Asian Elephants (Elephas Maximus) In Surin, Thailand, Pongpreecha Malaluang, Nuttapon Bangkaew, Jaruwan Chaiyakhot, Patinya Patikae, Nattaya Watwiengkam, Phimphanit Choklikitumnuey, Thanaphat Phupanna, Sudachanok Phowiset, Prim Chuesaard, Tarid Purisotayo

The Thai Journal of Veterinary Medicine

This study investigated the effects of social media-driven live-streaming dietary supplementation on the gastrointestinal microbial community of captive Asian elephants (Elephas maximus) at the Elephant Kingdom, Surin Province, Thailand. A hierarchical two-tier observational design was used: Tier 1 compared a minimal-supplementation control group (Group H, n = 6) with a frequent heterogeneous-supplementation group (Group L, n = 18); Tier 2 compared, within Group L, low-frequency (Group A, ≤ 3 sessions per week, n = 7) and high-frequency (Group B, > 3 sessions per week, n = 11) live-streaming sub-groups. Faecal microbial profiles were obtained by 16S rRNA gene (V3–V4) …

Antibacterial Efficacy Of Resin-Based Dental Composites Modified With Antibacterial Agents Against S. Mutans: A Systematic Review, Ahmad Setiawan Jarigau, Erwin Gunawan, Muhammad Akira Takashi Dharma, Fanny Dinda Nur Aulia, Lenni Indriani Hatta, Nurhayati Natsir

International Arab Journal of Dentistry

Introduction: Dental caries caused by Streptococcus mutans is a leading cause of dental restoration failure. Enhancing composite resins with antibacterial agents aims to inhibit bacterial growth and prolong restoration life.

Objectives: This review evaluates the anti-bacterial agents efficacy of these modified composites against S. mutans and explores their mechanisms and potential clinical benefits.

Methods: A comprehensive literature search was conducted across multiple databases following PRISMA guidelines, focusing on in vitro studies published between 2015 and 2025. Studies evaluating composites with antibacterial additives against S. mutans using standard microbiological assays were included. The quality of eligible studies was assessed using the …

Comparison Of Three Intraoral Scanners For Digital Impressions Of Biologically Oriented Preparation: An In-Vivo Study, Lara Habli, Pascale Habre-Hallage, Hani Tohme, Dany Noujaim, Maryse Nassif, Camille Haddad

International Arab Journal of Dentistry

Introduction: The accuracy of intraoral scanners (IOSs) in capturing a Biologically Oriented Preparation Technique (BOPT) remains uncertain. The aim of this study was to evaluate the accuracy of digital impressions obtained with three intraoral scanners for recording BOPT preparations.

Methods: A maxillary central incisor was prepared following BOPT. After temporization, a conventional polyvinyl siloxane impression was scanned with a desktop scanner to obtain a reference model. Forty-two scans (n D 14 per scanner) were recorded with three IOSs—Trios 3, Sirios, and Helios 680—by a single operator under standardized conditions. Accuracy was assessed using Geomagic Control X by calculating 3D surface …

Evaluation Of Optimal Force For Intrusion Of A Periodontally Compromised Maxillary Anterior Dentition Treated With Fixed Orthodontics – A Finite Element Analysis, Tanzim Ahmed, Amrita Puri, Aatira Nair, Anshul Singla, Mathew Koshy Vaidyan, Shruti Sharma, Chhavi Singh

International Arab Journal of Dentistry

Introduction: Adult orthodontic treatment is increasingly sought due to aesthetic and functional concerns, often involving periodontally compromised patients with altered biomechanics. Reduced bone support shifts the center of resistance and necessitates lower, carefully controlled forces, while finite element modeling has become a key tool to analyze tissue response under such conditions.

Objectives: The study aimed to determine the optimal intrusive force for periodontally compromised maxillary anterior teeth using Finite Element Analysis (FEA).

Methods: A 3D finite element model of the maxillary anterior dentition was created and divided into healthy and compromised halves, the latter with one-third alveolar bone loss. A …

Impact Of Antihypertensive Medications On Implant Success: A Retrospective Cohort Study On Monomedicated Patients, Antony Chidiac, Stephanie Mrad, Charbel Kachouh, Richard M. Sadaka, Joseph Bassil

International Arab Journal of Dentistry

Objective: The aim of this study main is to analyze the influence of antihypertensive treatments on the failure and survival rates of dental implants.

Methods: Medical records of 586 patients who received a total of 1,814 dental implants between 2012 and 2022 met the inclusion criteria and were retrospectively reviewed. Patients were divided into two groups: a control group comprising 512 systemically healthy patients with 1581 implants, and a group of 74 patients taking only antihypertensive medications who received a total of 233 implants. Implant failure was assessed according to criteria defined by the International Congress of Oral Implantologists.

Results: …

Hypo-Responsiveness Of The Dental Pulp In Patients With Type 2 Diabetes And Hypertension: A Cross-Sectional Study, Kavitha M, Mallolu Anthony Sanjana Vijay, Niveditha B, Fathima A.I, Pavithra D, Vigneshwaran J

International Arab Journal of Dentistry

Introduction: Diabetes mellitus and hypertension, two of the most prevalent metabolic disorders worldwide, exert profound and progressive effects on multiple physiological systems. While their systemic complications are well documented, their subtle yet clinically significant impact on oral structures, particularly the dental pulp, remains underexplored.

Objectives: This study aims to assess the functional responsiveness of dental pulp nerves in individuals with type 2 diabetes mellitus and systemic hypertension, and to compare the findings with responses from healthy individuals, using an Electric pulp tester (EPT) as a diagnostic tool.

Methods: A total of 600 teeth from 75 adult patients (25 diabetic, 25 …