Digital Commons Network^™

Core Temperature While Swimming In Warm Open Water With And Without A Wetsuit, Katsiaryna Afanasyeva

UNLV Theses, Dissertations, Professional Papers, and Capstones

Triathlon is a popular sport which attract participants from all over the world. In general, triathlon is a safe sport with risk of death being about 1.74 deaths per 100,000 participants (Harris et al., 2017). The swimming portion of the race can be dangerous, posing particular risks due to open water conditions and the physical demands of the event. This study investigated the effects of wetsuit use on core temperature in warm open-water swimming (27.9–28.3°C). Four experienced triathletes (2 males, 2 females; age 49.50 ± 7.83 years) completed two 700-meter open-water swims at a submaximal pace—once wearing their personal full-sleeve …

Plagiocephaly In Premature Infants: Enhancing Nicu Caregiver Education, Hailee Efferson

UNLV Theses, Dissertations, Professional Papers, and Capstones

Objective: To improve NICU nurses’ confidence in preventing and managing plagiocephaly in premature infants through a one-on-one educational session.Design: One-group post-test design for a quality improvement initiative. Setting: Neonatal Intensive Care Unit (NICU) at Summerlin Hospital Medical Center. Participants: 20 NICU Nurses. Measures: Post-session questionnaire including close-ended Likert scale and open-ended questions. Results: Mean scores ranged from 3.5 to 4.0, with the highest rating for the helpfulness of the session format (mean = 4.0) and the lowest for confidence in alternating infant positioning (mean = 3.5). Standard deviations ranged from 0 to 0.59, indicating strong agreement regarding the session format …

Exploring The Occupation Of Parenting With A Cognitive Disability, Alysa Polley

UNLV Theses, Dissertations, Professional Papers, and Capstones

Objective: To investigate how parents with cognitive disabilities perform child-rearing tasks and barriers associated with their disability, to determine their needs and self-efficacy to improve the role of occupational therapy in supporting child-rearing for parents with cognitive disability.Design: Qualitative Case-study, Phenomenology Setting: Gigi's Playhouse Participant(s): Inclusion criteria: parents or expecting parents, individuals with a cognitive disability resulting from an autism spectrum disorder diagnosis, English speaking, 18+, and autonomy to consent participation. Exclusion criteria: non-English speaking, individuals without a cognitive disability resulting from an autism spectrum disorder diagnosis, and under 18. Measure(s): Semi-Structured Interview and Tool for Measuring Parental Self-efficacy. Results: …

Qualitative Analysis Of Clinical And Community Perinatal Providers’ Perceived Barriers To Equitable Care For Food Insecurity In Underserved Communities In Southern Nevada, Kaelia Lynn KeapomekuʻUaloha Saniatan

UNLV Theses, Dissertations, Professional Papers, and Capstones

Food insecurity is prevalent among underserved communities and contributes to increasing maternal-child health disparities. The perinatal period from pregnancy through one year postpartum provides a critical window of opportunity to identify and address food insecurity (FI). However, barriers such as inadequate staffing, lack of institutional and community resources have prevented perinatal providers from offering equitable care for FI, defined as providing screening, referrals, and follow-up services. The Social Ecological Model (SEM) is a framework that observes concepts at multiple levels, including (i) individual, (ii) interpersonal, (iii) institutional, (iv) community, and (v) policy. The objective of this study is to understand …

The Effects Of Sugar Alcohols On The Growth Of Cariogenic Bacteria, Jake Sanders Boone

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study was to examine the potential of sugar alcohols, commonly used as sugar substitutes to reduce the activity of dental caries causing bacteria. Specifically, the sugar alcohols xylitol, erythritol, sorbitol, and mannitol were placed into the growth media of Streptococcus mutans and Lactobacillus acidophilus. The effects on their bacterial growth were observed. 10% xylitol, 10% erythritol, 10% sorbitol, 10% mannitol, 5% xylitol + 5% erythritol, and 3.3% erythritol + 3.3% xylitol + 3.3% sorbitol combinations were compared to the control groups for differences in bacterial growth. S. mutans samples were significantly inhibited by all groups except …

Emerging Adult Gamers: Nutritional Insights On Dietary Intake, Physical Well-Being, And Occupational Performance, Justine Dualan Tuason

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study aimed to gather insights from Emerging Adult (EA) gamers (between 18 and 24) regarding their nutritional literacy, dietary patterns, and its potential impacts on their occupational performance and physical well-being. There is a need to gather gamers' perspectives to identify the specific facilitators and barriers regarding their ability to discern appropriate dietary choices, as it provides more information regarding preventative and client-centered measures for future healthcare professionals. Occupational Therapists (OTs) are uniquely equipped to address this population's needs, as the profession's holistic principles allow for a well-rounded and sustainable approach. Additionally, growing emphasis is placed on preventative rather …

Prevalence Of Cardiovascular-Kidney-Metabolic Stages In Us Adolescents And Relationship To Social Determinants Of Health, Carissa M. Baker-Smith, Abigail M. Gauen, Lucia C. Petito, Sadiya S. Khan, Norrina B. Allen

Department of Pediatrics Faculty Papers

BACKGROUND: Risk factors for atherosclerotic cardiovascular disease begin in youth. Knowledge of the prevalence of cardio-kidney-metabolic (CKM) syndrome in adolescents and its risk factors is critical to understanding the cause of atherosclerotic cardiovascular disease risk burden.

METHODS: We conducted a cross-sectional analysis of the 2017 to 2020 US National Health and Nutrition Examination Survey data and determined the prevalence of each CKM stage in adolescents aged 12 to 18 years. We then assessed the relationship between the family income-to-poverty ratio, health insurance, routine health care access, food security, health behaviors, and CKM stage. We quantified associations between social factors, behaviors, …

Staff Education Program On The Vanderbilt Adhd Diagnostic Rating Scale, Rabiatu Bangura

Walden Dissertations and Doctoral Studies

This DNP project evaluated the effectiveness of a structured staff education program designed to enhance healthcare professionals’ knowledge and utilization of the Vanderbilt ADHD Assessment Scale (VAS) in children aged ≥2 to ≤18 years. The practice problem addressed in this project was the inconsistent use and limited knowledge of the VAS among healthcare staff, which can lead to underdiagnosis or delayed diagnosis. The practice-focused question was: Will a staff education program specifically designed to instruct healthcare professionals on using the Vanderbilt ADHD Assessment Scale in children ≥2 years to ≤18 years increase their knowledge? Targeted educational sessions were implemented, and …

Unlv Department Of Physical Therapy And The Fine Arts Clinic For Health And Injury Prevention, Madeline Cosgrove, Ashton Johnson, Keith Lopez, Diana Nguyen

UNLV Theses, Dissertations, Professional Papers, and Capstones

At the collegiate of performing arts, those who participate in classes and performances will often be at risk for musculoskeletal injury due to repetition and specific patterns of their movements. The establishment of a pro-bono physical therapy clinic for students enrolled in undergraduate and graduate-level fine arts programs may improve healthcare access for this often underserved community. The goals of this service learning project were to provide injury-prevention screenings to dancers and administer specialized physical therapy (PT) services in the form of evaluations and treatments to all students in the UNLV (University of Las Vegas, Nevada) College of Fine Arts …

Effects Of Altered Somatosensory Input On Gait Kinetics And Kinematics Via Different Footwear In Individuals With Chronic Post-Stroke Hemiparesis, Daniela Casillas, Lesley Ruiz

UNLV Theses, Dissertations, Professional Papers, and Capstones

Purpose/Hypothesis: Individuals with post-stroke hemiparesis walk with significant asymmetries, leading to slow, effortful walking, and a high risk of falls. One contributing factor is altered sensation on the plantar surface. Studies examining altered somatosensory input via insoles, vibration and other tactile stimuli observed improvements in hemiparesis gait. This study investigates whether altering somatosensory input through different footwear can affect kinetics, kinematics and muscle activity during walking post-stroke. We hypothesized the barefoot conditions would have increased dorsiflexion (heel-strike, swing), increased plantarflexion during toe-off, increased muscle activity and kinetics, compared to memory foam conditions.

Participants: 13 individuals with chronic post-stroke hemiparesis (4F/9M, …

Piloting The Inclusion Of Dollar Stores In The Modified Retail Food Environment Index (Mrfei) In Urban Clark County, Nevada, Tiana T. Tu

UNLV Theses, Dissertations, Professional Papers, and Capstones

Food insecurity is the condition of having limited or uncertain access to adequate food. It contributes to poor diet-related health outcomes which are in turn influenced by the food environment. The Centers for Disease Control and Prevention (CDC) developed the Modified Retail Food Environment Index (mRFEI) to characterize food environments by measuring the proportion of healthy and non-healthy retailers. The CDC mRFEI considers a variety of establishments but fails to include dollar stores, which contribute to the food environment by offering food and, in some cases, fresh produce. This study proposed an “expanded mRFEI” that modified the CDC mRFEI methodology …

Role Of The Pediatric Rdn In Conducting The Pediatric Nutrition Focused Physical Exam: Training, Clinical Practice And Barriers, Sarah M. Kowalewski

Masters Theses, 2020-current

Abstract:

Background: The pediatric nutrition focused physical exam (PNFPE) is important for completing comprehensive assessment in pediatric patients, particularly those at risk for malnutrition. The PNFPE helps to identify the depletion of fat and muscle stores, as well as micronutrient deficiencies.

Methods: Pediatric RDNs, self-identified through CDR and practice group membership, were surveyed-to investigate their training, clinical practice, documentation, and barriers to use of the PNFPE. The survey instrument, validated by content experts and analyzed for reliability, was approved by our university’s IRB.

Results: A total of 65.8% of respondents held a graduate degree and 81.6% held a specialty certification. …

Long-Term Efficacy Of Pembrolizumab And The Clinical Utility Of Ctdna In Locally Advanced Dmmr/Msi-H Solid Tumors, Michael Lapelusa, Wei Qiao, Bryan Iorgulescu, Francis San Lucas, Keyur Patel, Deepak Bhamidipati, Jane Varkey Thomas, Nancy You, Wai Chin Foo, Dipen Maru, Selvi Thirumurthi, Van Morris, Scott Kopetz, Michael Overman, Kaysia Ludford

Faculty, Staff and Student Publications

Neoadjuvant immunotherapy can induce pathologic complete response (pCR) in patients with localized deficient mismatch repair (dMMR)/microsatellite instability-high (MSI-H) tumors. The long-term outcomes of these patients are unknown, as is the clinical utility of measuring circulating tumor DNA (ctDNA). Follow-up was evaluated in patients enrolled in a phase II trial (NCT04082572) that evaluated the efficacy and safety of pembrolizumab in patients with localized dMMR/MSI-H tumors. The primary outcomes of this trial have previously been reported. 3-year EFS and OS rates were 80% (95% CI: 66% - 93%) and 94% (95% CI: 86% - 100%). Patients without detectable ctDNA after pembrolizumab had …

Family-Based Health Promotion To The Early Phases Of Pediatric Acute Lymphoblastic Leukemia Treatment: A Qualitative Review, Anna Van Asselt, Renee Gilbert, Hide Okuno, Ann M. Davis, Keith J. August, Carolyn R. Bates, Robert C. Gibler

Research Days

Introduction: Excessive weight gain during early phases of Acute Lymphoblastic Leukemia (ALL) treatment elevates risk for long-term morbidities, late effects, and secondary cancers. Behavioral factors including physical inactivity and poor diet quality play a significant role in weight outcomes. Existing health behavior and obesity interventions do not address challenges that children and families face during cancer treatment. The current study qualitatively investigated caregiver, child, and multi-disciplinary expert perspectives on health behavior engagement and intervention content for the future adaptation of NOURISH-ALL.

Method: Caregivers (N=11) and youth with ALL (N=6) in the first year of treatment completed semi-structured interviews …

Physician Assistant 20-Minute Introduction, Daniel Fidel Ferrer

Other Scholarly Works

No abstract provided.

Teaming Up For Better Health: An Interprofessional Collaborative Approach To Older Adult Oral Care, Deborah Dowd, Jodie Lopez, Jennifer Goodman

Utah Conference on Community Engagement

Oral health is a critical component of overall health, significantly influencing systemic diseases and the quality of life in older adults. Conditions such as xerostomia, swallowing difficulties, and poor oral self-care are associated with aspiration pneumonia. Integrating oral health into healthcare in long-term care facilities (LTCFs) is essential for preventing various conditions and improving quality of life. Effective oral hygiene is crucial in avoiding non-ventilator hospital-associated pneumonia by reducing oral biofilm and lowering the risk of pneumonia. Nurses' knowledge and care in oral health across healthcare settings are vital for positive health outcomes. Revising nursing curricula to incorporate oral health …

Sedentary Behavior And Light-Intensity Physical Activity During Pregnancy And Cardiovascular Health: A Science Advisory From The American Heart Association, Kara H. Whitaker, Bethany Barone Gibbs, Marie-France Hivert, Nour Makarem, Elizabeth Moxley, Jason Vaught, Kelly R. Evenson

Faculty Scholarship-Nursing

The Physical Activity Guidelines for Americans supports sitting less and moving more. Growing evidence suggests that a waking behavior profile with less sedentary behavior and more light-intensity physical activity is associated with more favorable cardiovascular health. Remarkably, little is known about how these behaviors relate to cardiovascular health during pregnancy. The purpose of this American Heart Association science advisory is to describe the existing evidence on devicemeasured sedentary behavior and light-intensity physical activity in relation to cardiovascular health during pregnancy and to make specific calls to action for future research to improve health outcomes and to promote health equity. Outcomes …

Chronic Inflammation: The Link Between A High Added Sugar Diet And Disease, Anna Collins

Senior Honors Theses

The modern diet includes many processed foods that contain added sugars, resulting in a significant increase in daily glucose and fructose consumption. Considering this, there is an increased effort to uncover the effects of excess sugar intake on the body’s health and metabolism. Strong evidence supports the connection between a high added sugar diet and the presence of chronic, low-grade inflammation due to cellular distress and metabolic dysfunction. Prolonged inflammatory responses are linked to tissue damage and the development of various metabolic diseases that are prevalent in modern society, such as obesity, fatty liver disease, cardiovascular disease, and type 2 …

Exploring The Relationship Between Diet And Mental Health, Emory Layne

Honors Theses

Dietary patterns in Western societies have shifted over the past century due to the rise of food manufacturing and technological advancements. Ultra-processed foods now account for approximately half of the daily energy intake in high-income countries. Similarly, the national mental health crisis emerged in the 21st century and worsened after the COVID-19 pandemic. The changes in diet have impacted the gut microbiome, which interacts with the brain through the bidirectional gut-brain axis. Research suggests the concept of the gut-brain axis is a principal indicator of diet’s impact on mental health. However, this area of research is still emerging and requires …

Physiologically Based And Population Pharmacokinetic Modeling Of Midazolam In Children With Obesity Using Real-World Data, Sean Mccann, Victória E. Helfer, Stephen J. Balevic, William J. Muller, John N. Van Den Anker, Amira Al-Uzri, Marisa L. Meyer, Sarah G. Anderson, Sitora Turdalieva, Andrea N. Edginton, Daniel Gonzalez, Best Pharmaceuticals For Children Act Pediatric Trials Network Steering Committee

Department of Pediatrics Faculty Papers

Children represent a highly complex and variable population for treatment, including interindividual differences in drug dose-exposure. Midazolam has been used as a sedative for hospitalized children on- and off-label; however, factors affecting interindividual variability (IIV) in observed clearance for this population are not fully understood and can result in extreme under- or overexposure. Obesity has been described as a significant influence on midazolam in adolescents, which could potentially alter drug exposure. The goal of this study was to use two modeling strategies to evaluate dose-exposure of midazolam in children with and without obesity. Population pharmacokinetic modeling assessed whether measures of …

Perceptions Of Perinatal Depression Among Immigrant Mothers: Screening Practices In Nurse Home Visitation, Silvia E. Arabia

Doctoral Projects

Screening for perinatal depression is a recommended strategy aimed at prevention and timely management of mood disruption in pregnancy and the postpartum (ACOG, 2024). Screening for perinatal depression is often integrated in evidence-based home visitation curriculums. The aim of this qualitative descriptive quality improvement project was to explore perceptions of perinatal depression among immigrant mothers engaged in nurse home visitation to identify barriers, if any, to disclosure and treatment of perinatal depression among a group at increased risk of developing perinatal depression (Gennaro, S., et al, 2016). Immigrant mothers residing in a large urban county in the San Francisco Bay …

The Nicu Nurse’S Aptitude In Teaching Neuroprotective Care To Caregivers Of Neonates, Lucy Bradley

Honors College Theses

Preterm neonates are at risk of developmental delays, behavioral problems, and mental health challenges. Neuroprotective care is essential to mitigate these risks, and nurses play a crucial role in educating caregivers on these practices. This study aims to investigate neonatal nurses' knowledge and confidence in teaching caregivers about neuroprotective care and to determine the extent to which caregivers implement these practices. A mixed-methods research design will be employed, using a survey to collect data from neonatal nurses who have at least one year of experience working in a NICU. The survey will assess nurses' understanding of neuroprotective care, their confidence …

Assessment Of The Risk Factors Affecting Diabetes Outcome In Kumasi Metropolis Of Ghana, Audrey Jacobs

Honors College Theses

This paper examines Kumasi Metropolis, Ghana risk factors for diabetes outcomes, considering the prominent determinants such as geographic location, income, and educational level. Such determinants play a role when it comes to shaping health outcomes, with research indicating positive correlation between per capita expenditure on healthcare and life expectancy. In spite of that, inequalities do occur, even in developing nations such as Ghana, where minimal health care investment impacts poor health outcomes. Socioeconomic factors, including low living conditions, poor access to healthcare, and illiteracy, reinforce health disparities, especially in rural areas. Informed by a review of past research, we hypothesized …

Assessing Knowledge, Attitudes, And Practices Regarding Refractive Errors And Spectacle Wear Among Children In Sana’A: A Cross-Sectional Study, Tariek Aldoais, Zakarya Rageh, Khaled Al-Hemyari, Saleh Altheeb, Abdulmogni Al-Barrag, Mahfouth Bamashmus

AUIQ Complementary Biological System

Background: Understanding the knowledge, attitudes, and practices (KAP) regarding refractive errors and spectacle use is essential for promoting eye health and effective vision correction, especially in children.

Objective: This study assessed the demographic characteristics, knowledge, attitudes, and practices of participants concerning refractive errors and spectacle use, focusing on correlations influencing these factors.

Methods: A cross-sectional study of 228 participants analyzed demographic data, duration of glasses use, and responses to a structured questionnaire on KAP related to refractive errors and spectacles.

Results: Among participants, 53.1% were female, and 45.2% were aged 8–13 years. Glasses use for 1–3 years was reported by …

Staff Education To Improve Gestational Diabetes Knowledge In Family Practice Staff, Lawretta Udogadi Aghomon

Walden Dissertations and Doctoral Studies

The project was a staff education program on gestational diabetes mellitus (GDM) that was carried out in an outpatient primary health facility to help improve staff knowledge of GDM. GDM is a pregnancy complication where women with no history of diabetes become hyperglycemic during their gestational period. According to the Centers for Disease Control and Prevention, the percentage of mothers giving birth who received a diagnosis of diabetes during pregnancy has increased in the last 10 years. Limited healthcare staff knowledge is a constraint in preventing the increase of GDM incidence. The practice-focused question was: Among healthcare staff at a …

Development Of A Light-Based Platform To Assess Cervical Mucus Barrier Function And Physical Mucus Properties, Elizabeth J. Buzbee

McKelvey School of Engineering Graduate Student Theses & Dissertations

Preterm birth is the leading cause of neonatal morbidity and mortality worldwide, yet current clinical tools for predicting its risk lack specificity and reliability. Cervical mucus plays a crucial role in maintaining pregnancy by forming a barrier that protects the uterus against infection. This study investigates the use of laser speckle rheology as a noninvasive technique to assess cervical mucus biomechanics. Synthetic cervical mucus was fabricated at varying hydration levels and tested using a conventional rheometer that confirmed that the mechanical properties of the synthetic mucus samples were representative of physiological cervical mucus. These results were compared to the complex …

The Experience Of Non-English Speaking Hispanic Patients During Kidney Transplant Evaluation, Ana Ivette Merced-Castro

Walden Dissertations and Doctoral Studies

There has been an increase in the incidence of Hispanics being diagnosed with end stage renal disease (ESRD), which has evolved from the rise in type 2 diabetes and hypertension. However, Hispanics and African American people are less likely to receive kidney transplants than non-Hispanic White individuals, and many Hispanics referred for transplants often do not complete the evaluation process due to its complexities. The purpose of this qualitative narrative descriptive study, guided by the socioeconomic model, was to explore the lived experiences of non-English-speaking Hispanic patients during the kidney transplant evaluation process. Six participants were recruited for the individual …

Relationships Between Health Behaviors And Markers Of Oxidative Stress And Inflammation On Blood Pressure, Alison M. Godfrey

Honors Scholar Theses

Background. Young adulthood is a period when cardiometabolic risk factors begin to emerge. Developing cardiometabolic risk early can increase the risk and severity of chronic illness across the lifespan. Despite this, young adults are often understudied particularly as it relates to major cardiometabolic risk factors such as blood pressure (BP) and risk of hypertension. Hypertension is a public health crisis and early indicators of hypertension risk should be more thoroughly researched. Therefore, the purpose of the presented thesis is to examine BP in young adults and two potential pathways by which risk may emerge in young adults; inflammation (C-Reactive …

Relationship Between Maternal Plasma Retinol And Provitamin A Carotenoids With Fetal And Infant Kidney Development, Anum Akbar

Theses & Dissertations

Vitamin A plays a critical role in fetal organ development. Studies suggest that maternal vitamin A deficiency affects fetal nephron numbers, potentially leading to smaller kidney sizes and an increased risk of chronic kidney disease later in life. However, human studies exploring maternal vitamin A's impact on fetal kidney development lack longitudinal data and within-cohort comparisons. Furthermore, the influence of provitamin A carotenoids (α-carotene, β-carotene, β-cryptoxanthin) on kidney size remains unexplored. This dissertation addresses these gaps by analyzing relationships between maternal and cord plasma retinol and provitamin A carotenoid concentrations with fetal and infant kidney sizes. Our prospective cohort …

Navigating Lipid Nanoparticle Design: From Microfluidic Optimization For Rna Delivery In Pancreatic Cancer To Extended-Release Formulations For Hiv-1 Therapy., Farhana Islam

Theses & Dissertations

Lipid nanoparticles (LNPs) have emerged as a powerful platform for the delivery of RNA and small-molecule therapeutics, enabling improved drug stability, biodistribution, and cellular uptake. This study explores the formulation and optimization of LNPs for two distinct therapeutic applications: (1) mRNA-based therapy for pancreatic cancer (PC) and (2) extended-action fostemsavir (FTR) delivery for HIV-1 treatment. For PC therapy, a library of 48 mRNA-LNP formulations was developed for intraperitoneal (IP) administration in an orthotopic pancreatic tumor mouse model. Using microfluidic assembly, LNPs were engineered with varying lipid compositions and characterized based on size, zeta potential, and cytotoxicity. Biodistribution and mRNA expression …