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Guidelines For The Nursing Home Appraiser And The Valuation Of Entrepreneurship In Nursing Home Ownership, William R. Parrish

Theses

The thesis, Guidelines for the Nursing Home Appraiser and the Valuation of Entrepreneurship in Nursing Home Ownership, explores the unique challenges in appraising nursing home properties. It emphasizes the critical role of federal and state regulations, reimbursement programs, and care requirements in influencing property values. The paper outlines appraisal methodologies, including the cost, income, and sales comparison approaches, and addresses the nuances of valuing skilled nursing facilities, intermediate care facilities, and residential care facilities. It highlights the impact of legislative acts such as TEFRA, DEFRA, COBRA, and OBRA on valuation standards, emphasizing their effect on Medicaid and Medicare participation. …

Coprolite Analysis: A Biological Perspective On Archaeology, Karl J. Reinhard, Baughn M. Bryant Jr

Karl Reinhard Publications

The most remarkable dietary remains recoverable from archaeological contexts are coprolites. Coprolites are desiccated or mineralized feces that are preserved in sheltered and open sites in arid regions, primarily in the New World. These dietary remains are remarkable from several perspectives. They typically contain a variety of macroscopic and microscopic remains that form interrelated data sets for the reconstruction of diets. Because contexts containing coprolites are typified by excellent preservation, the remains coprolites contain tend to be in better states of preservation than dietary remains recovered from nonfecal deposits. Coprolites also contain the well-preserved remains of intestinal parasites and pathogens …

Murder, She Wrote Or Was It Merely Selective Nontreatment?, George P. Smith Ii

Scholarly Articles

This article will both explore and thereby establish the medical, ethical, and legal validity of selective nontreatment of severely handicapped newborns. A construct for principled decision-making, tied to a basic recognition of the right of self-determination, as shaped by compassion and validated principles of triage and cost-benefit analysis, will be seen as the most effective means for the states-and not the federal government-to evaluate the intensely complex issues associated with allocating scarce medical resources to defective infants. Governmental intrusions into the familial decision- making forum in these circumstances must be kept to a minimum and allowed only in grave cases.

The Calendar - December 1991, Nova University

The Calendar

No abstract provided.

Time-Courses In The Retention Of Food Material In The Bivalves Potamocorbula Amurensis And Macoma Balthica: Significance To The Absorption Of Carbon And Chromium, Alan W. Decho, Samuel N. Luoma

Faculty Publications

Time courses for ingestion, retention and release via feces of microbial food was investigated using 2 bivalves with different feeding strategies, Potamocorbula amurensis, and Macoma balthica. The results showed 2 pathways for the uptake of food material in these clams. The first is represented by an initial label pulse in the feces. The second pathway operates over longer time periods. Inert ⁵¹Cr-labeled beads were used to determine time frames for these pathways. The first pathway, involving extracellular digestion and intestinal uptake, is relatively inefficient in the digestion of bacterial cells by P. amurensis but more efficient in …

A Novel Transposon Trap For Mycobacteria: Isolation And Characterization Of Is1096, Jeffrey D. Cirillo, Raul G. Barletta, Barry R. Bloom, William R. Jacobs Jr.

School of Veterinary and Biomedical Sciences: Faculty Publications

In the course of developing strategies to obtain a mutation in the aspartate semialdehyde dehydrogenase (asd) gene of Mycobacterium smegmatis, an efficient transposon trap was constructed which may be generally useful for the identification of transposable elements in mycobacteria. A DNA fragment containing the asd gene was replaced with an aminoglycoside phosphotransferase gene (aph) to generate a Δasd::aph allele. Attempts to replace the wild-type asd gene with the Δasd::aph allele were unsuccessful, suggesting that this deletion was lethal to the growth of M. smegmatis. The plasmid, pYUB215, which …

A Polymerase Chain Reaction-Based Method To Detect Cisplatin Adducts In Specific Genes, M M. Jennerwein, A Eastman

Dartmouth Scholarship

Every bulky lesion in DNA can potentially inhibit the Taq DNA polymerase and thereby decrease the amplification produced in the polymerase chain reaction. We investigated the feasibility of using this inhibition to quantify DNA lesions produced by the anticancer drug cisplatin. Products were detected by electrophoresis followed by ethidium bromide staining. Quantitation was obtained by including [³²P]dCTP in the amplification reaction and subsequently assessing the incorporated radioactivity. Hamster genomic DNA was platinated in vitro to defined levels and amplified with primers that produce either a 150, 750 or 2,000 base pair fragment. The degree of inhibition of PCR …

The Effect Of Otitis Media On Articulation In Expressive Language-Delayed Children, Marla Lohr-Flanders

Dissertations and Theses

Researchers have long been concerned with the effects of otitis media on speech and language acquisition because of the high correlation of a mild to moderate hearing loss during the time period that fluid (effusion) may be in the middle ear. Middle-ear effusion would prevent many of the auditory messages from accurately reaching the nervous system (Zinkus, 1986). Deprived of the ability to discern the subtle acoustic differences that provide information for phonetic contrasts, a child's speech acquisition may differ from children who do not experience such losses.

The present study examined the relationship between an early history of otitis …

[Book Review Of] The Singer-Affaire, By Hiram Caton, D.Litt., Director, The Bonhoeffer Institute, Catholic Physicians' Guild

The Linacre Quarterly

No abstract provided.

The Calendar - November 1991, Nova University

The Calendar

No abstract provided.

Owning And Controlling Technical Information, Vivian Weil

Center for the Study of Ethics in Society Papers

Presented to the WMU Center for the Study of Ethics in Society, April 5, 1990.

Regulation Of Transforming Growth Factor-Beta 1 Gene Expression By Glucocorticoids In Normal Human T Lymphocytes., O. Ayanlarbatuman, A. P. Ferrero, Arturo Diaz, Sergio A. Jimenez

Department of Medicine Faculty Papers

Glucocorticoids (GC) modulate immune function in a number of ways, including suppression of T cell proliferation and other IL-2-mediated T cell functions. These inhibitory effects are similar to those induced by transforming growth factor-beta 1 (TGF-beta 1), a cytokine with potent T cell inhibiting activities. We examined the hypothesis that GC effects may be at least partially achieved through modulation of the expression of the TGF-beta 1 gene in activated T cells. Normal T cells were cultured with or without purified phytohemagglutinin (PHA-p) and 4 beta-phorbol 12-myristate 13-acetate (PMA) in the presence or absence of the synthetic GC, dexamethasone (100-200 …

1991 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

The Aids Project Newsline, Vol.4, No.3 (Fall 1991), Jeffrey Levensaler, Wendy Morse, The Aids Project

AIDS Project Newsline (1991-1996)

No abstract provided.

The Calendar - October 1991, Nova University

The Calendar

No abstract provided.

Digest Of The Philadelphia College Of Osteopathic Medicine (Fall 1991), Philadelphia College Of Osteopathic Medicine

Digest

The Fall 1991 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Renovations and New Construction Continue
• PCOM Fundraising Goes Back to Basics
• Curriculum Changes
• President's Perspective
• Geriatric Care to be Stressed Early, Often
• PCOM Hosts Conference in Osteopathic Hospitals and Medical Education
• Unique DO-MBA Program Teaches the Business of Medicine
• PCOM Students Go Far for Rural Clinical Experience
• Where are Our 111 Residents?
• On Campus
• A "3-D" View of the Future
• Class Acts
• In Memoriam
• Coming Events

The Chironian Vol. 108 Fall 1991, New York Medical College

The Chironian

No abstract provided.

Osteoinductivity Of Demineralized Bone: A Quantitative In Vitro Assessment, Yihong Zheng

Biological Sciences Theses & Dissertations

Acid demineralized bone (DMB) implanted in extraosseous sites induces bone formation. In vivo studies have shown that DMB stimulates the differentiation of mesenchymal cells into osteogenic cells. In this study an in vitro system was developed to demonstrate the osteoinductivity of DMB quantitatively. This in vitro working system was used to assess the osteoinductivity of variously processed DMB products as a means to evaluate their processing protocols. A human dermal fibroblastic (HDF) cell line was initiated from tissue explants as a working model, along with a human periosteal (HPO) cell line as a control. Ground DMB processed by LifeNet Transplant …

Lac+ Saccharomyces Cerevisiae, Robert C. Dickson, Kotikanyadanam K. Sreekrishna

Molecular and Cellular Biochemistry Faculty Patents

The invention relates to novel, transformed strains of Lac⁺ Saccharomyces cerevisiae, capable of utilizing lactose as a sole carbon source, produced by inserting into the Saccharomyces cerevisiae a plasmid containing a lactose permease and a beta-galactosidase gene derived from Kluyveromyces lactis yeast.

Risk Perception And Drug Safety Evaluation, Ilan B. Vertinsky, Donald A. Wehrung

RISK: Health, Safety & Environment (1990-2002)

The authors present a Risk communication framework based on a survey of empirical research concerning public Risk perceptions. They also apply it to the area of pharmaceutical regulation to suggest more effective regulatory strategies.

Prehospital Care Of Acute Myocardial Infarction: A Review, Asit R. Gokli, Jay L. Kovar, Terry Kowalenko, Richard M. Nowak

Henry Ford Hospital Medical Journal

Each year more than 1 million people in the United States suffer from acute myocardial infarction (Ml) with most of the deaths occurring within hours of symptom onset. Over the last 25 years, different prehospital systems have evolved throughout the world which allow early cardiac monitoring and treatment of acute Ml patients. Thrombolytic therapy in acute Ml has been shown to decrease mortality and preserve left ventricular function when administered early after onset of symptoms. The potential role of Emergency Medical Services or Mobile Coronary Care Units in achieving early thrombolysis is under investigation. Several studies of prehospital interventions to …

The Calendar - September 1991, Nova University

The Calendar

No abstract provided.

Actinobacillus Pleuropneumoniae-Induced Thymic Lesions In Mice And Pigs, D.L. Stine, M.J. Huether, Rodney A. Moxley, Subramaniam Srikumaran

School of Veterinary and Biomedical Sciences: Faculty Publications

Actinobacillus pkuropneumoniae produces several hemolysins/cytotoxins that may be important in the pathogenesis of acute lesions. Little is known, however, about the role of these virulence factors in chronic disease or the carrier state. We investigated the effects of live bacterial infection and transthoracic injection of a sterile culture supernatant on primary lymphoid organs and lymphocyte populations. Transthoracic inoculation of mice or intranasal inoculation of pigs with virulent A. pleuropneumoniae serotypes 1 and 7 induced thymic cortical lymphoid necrosis. These lesions were reproduced in mice by transthoracic injection of a concentrated sterile culture supernatant. The cytotoxic effect of this culture supernatant …

Expression Of A Human Cartilage Procollagen Gene (Col2a1) In Mouse 3t3 Cells., Leena Ala-Kokko, James Hyland, Carol Smith, Kari I. Kivirikko, Sergio A. Jimenez, Darwin J. Prockop

Department of Medicine Faculty Papers

Expression in a recombinant system has been difficult to obtain for any of the major fibrillar collagens that require processing by eight or more post-translational enzymes. Here, two DNA constructs were designed so that the promoter region of the gene for the pro-alpha 1(I) chain of human type I procollagen drove expression of the human type II procollagen gene in mouse NIH 3T3 cells, a culture line that normally synthesizes type I procollagen but not any cartilage-specific protein such as type II procollagen. Both constructs were expressed as both mRNA and protein. In clones expressing the construct at high levels, …

The Effects Of A Teaching Program About Aids Prevention On The Knowledge, Attitudes, And Behaviors Of High School Students, Deborah Whitehead

MSN Research Projects

As the number of adolescents contracting Acquired Immunodeficiency Syndrome (AIDS) increases, the importance of educational interventions to change behaviors, attitudes, and knowledge regarding AIDS becomes more significant. The purpose of this study was to ascertain the effects of a teaching program about AIDS prevention on the knowledge, attitudes, and behaviors of high school students. Orem's Self-Care Theory was used to guide this quasi-experimental study. The sample consisted of 49 twelfth-grade students who were drawn from two high schools in rural Northeast Mississippi. The Student Health survey was utilized to assess students' knowledge, attitudes, and behaviors about AIDS. Descriptive analysis and …

Communication And Socialization Skills At Ages 2 And 3 In "Late-Talking" Young Children, Rhea Paul, Shawn S. Looney, Pamela S. Dahm

Communication Disorders Faculty Publications

Twenty-one apparently normal children between 18 and 34 months of age with slow expressive language acquisition were compared to a group of normally speaking children matched for age, SES, and sex ratio, on the Vineland Adaptive Behavior Scales (Sparrow, Balla, & Cicchetti, 1984). The late talkers (LTs) scored significantly lower not only in expressive communication, but also in receptive communication and socialization. A follow-up study of the same subjects, seen at age 3, showed nearly half the 3-year-olds with a history of LT remained delayed in expressive communication and socialization, while one third remained behind in receptive language. The data …

What's Happening: July 31, 1991, Maine Medical Center

What's Happening

No abstract provided.

Phenylbutyl Nitrone Compositions And Methods For Prevention Of Gastric Ulceration, Robert A. Floyd, John M. Carney

Pharmacology and Nutritional Sciences Faculty Patents

Compositions containing PBN, or active derivatives thereof, in a suitable pharmaceutical carrier for administration to a patient, are disclosed for treating or preventing gastric ulceration caused by ingestion of non-steroidal anti-inflammatories. Based on animal studies, the dosage is in the range of 3 to 300 mg/kg and is administered prior to, simultaneously, or shortly after ingestion of the NSAID compound(s). In the preferred embodiment, the range is between 10 and 30 mg/kg, depending on the dosage unit required to protect the mucosa. The preferred method of administration is orally, alone or in combination with the non-steroidal anti-inflammatory. It is believed …

3-Hydroxy-N-Methylpyrrolidone And Use As Transdermal Enhancer, George A. Digenis, Walter J. Doll, Amale Hawi

Pharmaceutical Sciences Faculty Patents

The novel compound, 3-hydroxy-N-methylpyrrolidone, is effective as a transdermal enhancer for the absorption of drugs through the skin of humans and animals. The 3-hydroxy-N-methylpyrrolidone is prepared from delta-butyrolactone which is converted to methyl 2,4-dibromobutyrate, this intermediate is reacted with methylamine to form N-methyl-2,4-dibromobutyramide, this intermediate is converted to 3-bromo-N-methyl-2-pyrrolidone by ring closure, and the 3-bromo-N-methyl-2-pyrrolidone is reacted with an alkaline earth metal carbonate or alkaline metal carbonate to form 3-hydroxy-N-methyl-2-pyrrolidone.

What's Happening: July 3, 1991, Maine Medical Center

What's Happening

No abstract provided.