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Kujdesi Infermieror Tek Pacientët Me Infeksione Respiratore, Egzona Jashari

Theses and Dissertations

Në këtë punim do t’i trajtojmë disa infeksione të sistemit respiratore. Objektivi i përgjithshëm i temës së diplomës është të ofrojmë njohuri për infeksionet respiratore që të ngrihet vetëdijsimi i popullatës për infeksione respiratore që dita e ditës po bëhet një problem për shëndetin dhe mirëqenien e individëve. Njohja e infeksioneve respiratore është shumë e rëndsishme në parandalimin dhe trajtimin e infeksioneve respiratore si: njohja e simptomave, njohja e shkaktarëve si dhe për faktorët specifik që paraqiten tek infeksionet respiratore. Objektivi specifik është të krijojmë njohuri rreth mënyrës së trajtimit dhe diagnostikimit të këtyre infeksioneve dhe masat të cilat duhet …

Medicine And Media: The Ranitidine Debate., Jennifer A. Wagner, Jennifer Colombo

Manuscripts, Articles, Book Chapters and Other Papers

Ranitidine has been the topic of recent media reports. Current findings, confirmed by the US Food and Drug Administration, indicate that some ranitidine products contain a substance that may be carcinogenic. Providers and patients require additional information on the risks of continuing therapy vs. the benefits of the medication. This article comments on what is currently known about the evolving situation of elevated N-nitrosodimethylamine levels in ranitidine and the limits of the existing information to assess best practices.

American Heart Association Epi|Lifestyle Scientific Sessions: 2020 Meeting Highlights, Alexander C. Razavi, Véronique Gingras, Erin D. Michos, Ann Marie Navar, Sherry Ann Brown, Erin Delker, Kathryn Foti, Stéphanie Harrison, Yifei Lu, Jovia L. Nierenberg, Jewel Scott Phd, Rn, Fnp-C, Olive Tang, Alvin G. Thomas, Ruth Alma Turkson-Ocran, Amelia Wallace, Mingyu Zhang, Kristie J. Lancaster, Pamela L. Lutsey, Elizabeth Selvin

Faculty Publications

No abstract provided.

American Heart Association Epi|Lifestyle Scientific Sessions: 2020 Meeting Highlights, Alexander C. Razavi, Véronique Gingras, Erin D. Michos, Ann Marie Navar, Sherry Ann Brown, Erin Delker, Kathryn Foti, Stéphanie Harrison, Yifei Lu, Jovia L. Nierenberg, Jewel Scott Phd, Rn, Fnp-C, Olive Tang, Alvin G. Thomas, Ruth Alma Turkson-Ocran, Amelia Wallace, Mingyu Zhang, Kristie J. Lancaster, Pamela L. Lutsey, Elizabeth Selvin

Faculty Publications

No abstract provided.

Nurses And Needlesticks: Perceptions Of Stigma And Hiv Risk, Bethany Sharon Moore

USF Tampa Graduate Theses and Dissertations

Health-care providers (HCPs) are vulnerable to occupational health hazards, including dirty needle-stick injuries (DNSIs), which increase the risk for infection with HIV and other blood-borne pathogens. This study examines the perceptions of nurses and nurse practitioners who work in various health care settings regarding HIV-risk and DNSIs, in order to ascertain how these perceptions inform their decision-making regarding their health and nursing practice. I utilize a phenomenological approach to analyze the lived reality and embodiment of the DNSI experience by HCPs. The study explores the personal and institutional level factors that may influence the timely reporting and treatment of DNSIs, …

Mechanisms Of Bak Activation In The Initiation Of Mitochondrial Apoptosis, Geetika Singh

Theses and Dissertations (ETD)

Mitochondrial apoptosis is crucial for normal mammalian development and adult homeostasis being regulated by B-Cell Lymphoma-2 (BCL-2) proteins. Deregulation of BCL-2 proteins form the basis for myriad of human pathologies including cancer and autoimmune diseases. Therefore, BCL-2 proteins are considered key therapeutic targets. BCL-2 homologous antagonist/killer (BAK) is an effector of outer mitochondrial membrane (OMM) pemeabilization or mitochondrial poration. Despite progress in understanding BAK-mediated mitochondrial poration, the underlying multi-step mechanism is not clearly defined. Here, we provide mechanistic details on the early steps in this process related to BAK activation, including transient direct activation and autoactivation. We demonstrate for the …

The Freedom To Move: Dance/Movement Therapy And Survivors Of Trafficking - An Evolving Practice, Rebecca Richardson

Expressive Therapies Capstone Theses

Abstract

Human/Sex trafficking is the use of force or coercion for the purpose of exploiting humans (mainly women) for sex or labor. Consequences of being trafficked include psychological and physical symptoms that may hinder the survivors for the rest of their life if not treated. Survivors of human trafficking are infrequently researched and have limited evidence-based methods of treatment. Even fewer studies have been conducted involving the use of dance/movement therapy with survivors of trafficking. dance/movement therapy is vital to treatment because of its focus on integrating the body with the mind. In this literature review I discuss the effects …

A Pbpk Model For Clearance Of Pegylated Nanomedicines, Anne M. Talkington, Samuel K. Lai, M. Gregory Forest

Biology and Medicine Through Mathematics Conference

No abstract provided.

Comparisons Of Patellar Bone Mineral Density Between Individuals With And Without Patellofemoral Pain, Chris Khuu, Allina Cummins, Steven Shepherd

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: Although bone stress injuries have been reported in individuals with patellofemoral pain (PFP), especially within the lateral patella, it remains unclear whether persons with PFP exhibit altered patellar regional bone mineral density (BMD). The primary purpose of this study was to compare BMD of the patella (lateral, medial, and total regions) between individuals with and without PFP using quantitative computed tomography (QCT). The secondary aim was to examine the associations between patellar regional BMD and patellofemoral joint (PFJ) alignment. Methods: Ten individuals with retropatellar pain and 10 sex, age, weight, height, and activity matched pain-free controls underwent a QCT …

Laryngotracheal Stenosis, Kelsey Stuckey

Doctor of Nursing Practice Projects

Laryngotracheal stenosis (LTS) is the luminal compromise at the laryngeal, subglottic, or tracheal level (Gelbard et al., 2014). Various etiologies for LTS exist. Endotracheal cuff over-inflation, inappropriately sized endotracheal tubes, and sudden movements of the tube contribute to injury, as well as anatomical differences(Cardillo et al., 2010; Divatia & Bhowmick, 2005; Medina et al., 2009; Miñambres et al., 2009; Nikolovski et al., 2019; Zaghi et al.,2016). The influence of estrogen may contribute to the development of LTS in women during the third through fifth decades Dedo & Catten, 2001; Poetker et al., 2006; Valdez & Shapshay, 2002). The project goal …

Effect Of Ambient Temperature On Recovery Of Surgically Instrumented Sprague-Dawley Rats, Gianna Mangone

Senior Honors Projects, 2020-current

Based on current guidelines for housing rodents after surgical instrumentation, rodents may be housed at temperatures that hinder surgical recovery and cause thermal stress– room temperature (21°C) being one of them. Rodents are often housed at room temperature since this temperature is easy for humans to be caring for them. However, if recovering rodents are thermally stressed, experimental results will be confounded. To address this issue, Sprague-Dawley rats were surgically instrumented with radiotelemtry thermoprobes (Data Sciences, #TA-10F40) to monitor their core temperatures, then housed at one of five temperatures to assess the effect ambient temperature had on multiple aspects of …

Effect Of Protein, Fat, And Both Protein And Fat On The Glycemic Response Of A High Glycemic Index Meal, Muhammed Taai

Theses & Dissertations

Research Focus: Elevated blood glucose (BG) levels from a diet high in refined carbohydrates, even in the absence of diabetes, may increase the risk for chronic diseases including cardiovascular disease, type 2 diabetes, and obesity. The purpose of this study was to determine if supplementation of a high glycemic load breakfast with protein, fat, or a combination of the two attenuates the glycemic response in non-diabetic subjects.

Research Methods: Thirteen healthy adults, age 24.7±4y, BMI 25.1±4.5 completed four trials, having fasted 8-12h for this randomized, double-blind crossover study.

Fasting BG was measured, then subjects consumed 2 slices of white …

Breakfast Boost Study: Defining The Role Of Breakfast Macronutrient Composition On Markers Of Childhood Obesity, Caroline Ganoung

Human Nutrition and Hospitality Management Undergraduate Honors Theses

Abstract

Background: Childhood obesity is a serious problem in the United States, affecting ~19% of children 2-19 years of age. Breakfast is a key component of a healthy diet and can positively impact children’s health. However, there has been a steady decline in breakfast consumption in children over the past 40 years.

Methods: The objective of this study was to determine if breakfast macronutrient composition, protein (PRO)-based breakfast (30 g protein, 31 g carbohydrate, 11.7 g fat) or an isocaloric (360 kcal) carbohydrate (CHO)-based breakfast (13 g protein, 48 g carbohydrate, 11.7 g fat), can influence postprandial appetite and food …

Evaluating The Effects Of Detergent Concentration On The Reendothelialization And Ultrastructure Of Porcine Internal Thoracic Artery Scaffolds, Jesse Bruce Kooistra

Graduate Theses

Cardiovascular disease exerts a consistent force of morbidity and mortality on the global population. This pressure has created a demand for reliable replacement vascular tissues. Current solutions include synthetic grafts and biological transplant options that are associated with a multitude of complications. Therefore, the continued innovation of vascular tissue replacement solutions is warranted. Decellularized vascular tissues have been previously utilized as scaffolds upon which recellularized tissue engineered vascular solutions are constructed. However the interplay between decellularization agent concentration and effective recellularization has not been well documented. Herein we investigate this relationship through a detail oriented research model that both qualifies …

The Impact Of Forces On Knee Ligaments: A Biomechanical Analysis, Hannah Couture

Honors Projects in Science and Technology

Anatomy of the human body is complicated, and it impacts human physiology in every way, shape, and form. The application of physics in mechanical models creates simplified systems to help understand more complex structures. This paper looks at how anatomical research informed the creation of a two-dimensional computational model of the knee joint. The existing research and literature on the anterior cruciate ligament (ACL), the posterior cruciate ligament (PCL), the lateral collateral ligament (LCL), and the medial collateral ligament (MCL) is quite plentiful. The posterolateral corner (PLC), however is less studied in both anatomical research and its impact on surrounding …

Effect Of Maternal Microbiome On Offspring Neurodevelopment: A Review, Zoe Beausoleil

PCOM Capstone Projects

The purpose of this paper is to delve into the maternal influence on the offspring microbiome, and how maternal lifestyle factors and choices; mode of birth, feeding method, stress and the interventions used to alleviate said stress, maternal age, substance use, exercise, and nutrition, alter the microbiome and therefore affect the neurodevelopment of the offspring. The human microbiome is composed of billions of bacteria, fungi, protozoa, and viruses that occupy the gut, skin and other areas of the body. Numerous studies have illustrated the importance of the microbiome in healthy human physiologic processes including energy metabolism, gut health, immune function …

The Effects Of Total Body Proton Irradiation On Mouse Myometrium, Lillith Bulawa

Undergraduate Honors Theses

The boundaries of human space exploration continue to expand with new technology and discoveries making it even more important to investigate the effects of space on biological systems. Although humans have explored space in small increments, reproductive studies must be conducted to determine if stable short- or long-term residences for humans can exist in space. This study explored the effects of whole-body proton radiation on uterine smooth muscle known as the myometrium. Two types of mice utilized in this study were C57BL/6 and B6.129S6Cybbtm1Din/J NOX2 knockout mice. C57BL/6 mice are standard laboratory mice that were used to represent the wildtype …

Comparing Heatwave Related Mortality Data From Distressed Counties To Affluent Counties In Central And Southern Central Appalachia, Miranda Taylor Pardue

Undergraduate Honors Theses

The Appalachian Mountains are home to some of the most culturally rich places in the United States, but also some of the most impoverished communities as well. Several recent events support climate change across the globe. It is expected that Appalachian communities may suffer more dire consequences, as many communities lack strategies to help relieve some of the worst effects of climate change. Heatwaves are predicted to increase in duration and frequency over time, and communities that are not well prepared for the damaging effects of heatwaves can suffer unduly. This study aims to quantify the likelihood that people living …

Equivalency Testing For Two Formulations Of A Clinical Laboratory Control Material, Jessica M. Hart

Capstone Experience: Master of Public Health

Clinical laboratory control materials are an integral part of legally-mandated and highly regulated quality control protocols in all clinical laboratories. These controls ensure accurate performance of the laboratory testing and instrumentation used to produce medical test results for millions of patients. It is of clinical and public health interest to ensure the diagnostic test results which affect so many people are regulated by the most accurate and precise controls.

Formulation changes in control materials have the potential to impact laboratory quality control. In this study, data from two formulations of a hematology control were compared to assess equivalency of the …

Indices Of Metabolic Stress Following Resistance Exercise, Steven Alexander Long

Dissertations and Theses @ UNI

The purpose of this study was twofold: 1). to evaluate the metabolic responses to varying volume load (VL), manipulated through relative training intensity and 2). to evaluate the metabolic response to training via direct and indirect methods to assess the application potential of non-invasive methods. Recreationally trained male weight lifters (n = 11) volunteered to participate in this resistance training (RT) study. During three separate testing sessions, participants completed three sets of repetitions of the barbell bicep curl exercise to technical failure with short inter-set rest intervals (60 seconds). Participants were randomly assigned one of three training intensities immediately prior …

Effect Of Different Music Genres On Cognitive Task Performance After High Intensity Interval Training, Derek Jones

Longwood Senior Theses

The effects of high intensity exercise on cognitive performance are not fully understood. Music can affect physiological responses to exercise which may also impact cognitive performance. The aim of this study was to determine if music could impact cognitive performance after a bout of high intensity exercise. METHODS: Twelve subjects (n=7 males, n=5 females, 20.3 ± 1.7 y; 72.2 ± 14.9 kg; 1.70 ± 0.09 m) completed the Stroop test after a short (12 min) bout of high intensity interval exercise while listening to either Classical, Rock, or No Music. Subjects completed the Brunel Music Rating Inventory after listening to …

Temporal Pain Pattern Sequencing In The Older Adult After Joint Replacement Surgery, Jennifer B. Withall

Theses & Dissertations

Background

Large joint replacement surgery, including hip and knee arthroplasties, are two of the most common surgical procedures that American adults aged 65 years and older undergo annually. While postoperative pain is expected, if it is not properly managed, it can have deleterious effects on postoperative recovery, including an increased length of stay, increased risk for postoperative complications, and decreased patient satisfaction.

Problem

Postoperative pain is primarily managed pharmacologically, typically with opioid pain medications are administered as needed (i.e., pro re nata [PRN]). Patients request pain-relieving medications when they are experiencing escalating pain, which can be challenging to maintain comfort …

Approaches To Overcome Flow Cytometry Limitations In The Analysis Of Cells From Veterinary Relevant Species, Julia Hunka, John T. Riley, Gudrun F. Debes

Department of Microbiology and Immunology Faculty Papers

BACKGROUND: Flow cytometry is a powerful tool for the multiparameter analysis of leukocyte subsets on the single cell level. Recent advances have greatly increased the number of fluorochrome-labeled antibodies in flow cytometry. In particular, an increase in available fluorochromes with distinct excitation and emission spectra combined with novel multicolor flow cytometers with several lasers have enhanced the generation of multidimensional expression data for leukocytes and other cell types. However, these advances have mainly benefited the analysis of human or mouse cell samples given the lack of reagents for most animal species. The flow cytometric analysis of important veterinary, agricultural, wildlife, …

Electronic Image Detectability Under Varying Illumination Conditions, Jeremy J. Miller

Theses and Dissertations

Light in the built environment plays an essential role in the vision and the health of humans through non-visual receptors in the eyes. Unfortunately, image analysts and other Air Force personnel who engage in the detection of objects on softcopy displays are often required to work in very dimly-lit or dark environments as higher illumination reduces the contrast of displayed information. Literature has shown that increases in light exposure improves circadian rhythm entrainment and reduces the negative health consequences of insufficient lighting. This research examines the effects of indoor lighting to determine if increases in ambient illumination or changes to …

Vascular Deficits In Native American Women With Metabolic Syndrome During Dynamic Exercise, Jerene Yazzie, Giselle Quiver, Abraham Gomez, Sydnee Yazzie, Ariel Gomez, Klaudia Szych, Matthew A. Barlow Phd

International Journal of Exercise Science: Conference Proceedings

Native Americans of the Southwest are predisposed to vascular diseases due to health disparate lifestyles influenced by diet, lack of exercise and decreased access to health care. These factors together may be responsible for the co-morbidities developed with Diabetes and Metabolic Syndrome (MetSyn) which are indicators of early onset cardiovascular disease. In a previous study, we evaluated Native Americans (NA) diagnosed with MetSyn or Type II Diabetes and compared the sedentary control NA and Caucasians (CA) during vascular measurements of FMD. We found that NA Control and MetSyn groups exhibited a decrease in vascular function during rate to peak and …

The Effect Of Acute Consumption Of Overtime Essential Amino Acids Sports Drink On Delayed Onset Muscle Soreness In The Older Sedentary Population, Andi Johnson, Grant Wagner, Abraham Gomez, Jerene Yazzie, Klaudia Szych, Matthew A. Barlow Phd

International Journal of Exercise Science: Conference Proceedings

Essential amino acids are necessary for nutrition whether obtained by digestion of proteins or by oral supplementation of amino acids. The elderly experience loss of skeletal muscles and decrease in their strength and function, which can lead to poor quality of life. Increased quantity and quality of proteins stimulates muscle protein synthesis that can help combat this natural aging process. Purpose: The aim of this study was to see if consumption of essential amino acid drink high concentrations of leucin (2040 mg/serving) during exercise will attenuate the condition of Delayed Onset Muscle Soreness in the elderly. Also, we aimed to …

A Neural Mechanism For Capnotaxis In The Naked Mole-Rat, Michael Zions

Dissertations, Theses, and Capstone Projects

A Neural Mechanism for Capnotaxis in the Naked Mole-Rat

The Naked Mole-Rat (NM-R) is a small hairless rodent that has thrived underground in the Horn of Africa for the past 40 million years. It was first discovered in 1847, but has only been maintained in captivity and studied as a laboratory animal over the past 40 years. To date, more than 400 scientific papers have been published on this species. This is relatively few compared to established lab animals like rats and mice, but those papers contain a trove of information that has changed our understanding of the constraints of …

Effects Of Deceptive Footwear Condition On Subjective Comfort And Running Biomechanics, Zoe Y.S. Chan, Ivan P.H. Au, Janet H. Zhang-Lea, Reed Ferber, Gary Shum, Winko W. An, Roy T.H. Cheung

Human Physiology Faculty Scholarship

Comfort is a major criterion for footwear selection. Previous studies have suggested that physical properties were not enough to predict comfort and psychological factors could also affect the perception. To understand comfort, this study examined the effect of controlled shoe description and price cue on the perception of comfort. Furthermore, this study also examined the running biomechanics in response to footwear conditions of differing comfort. Fifteen runners completed treadmill running tests in two conditions: Shoe A and Shoe B. The same pair of neutral running shoes was used in both conditions, yet, Shoe B was described to be the “latest …

Analyses Of The 2019 Nobel Prize In Physiology Or Medicine: Molecular Machinery For Cellular Oxygen Level Response, Neyda V. Gilman

Library Scholarship

Gregg L. Semenza, William G Kaelin, Jr, and Sir Peter J. Ratcliffe were awarded the 2019 Nobel Prize for Physiology or Medicine on October 7, 2019. Their work led to the understanding of how cells recognize and adapt to varying oxygen levels. Hypoxia-inducible nuclear factors play an essential role in this mechanism by turning on other genes that work towards increasing oxygen levels in hypoxic environments. Other vital pieces of the machinery include von Hippel-Lindau proteins and prolyl hydroxylation. Due to the necessity of oxygen in numerous human physiological systems, this discovery will likely have nearly immeasurable impacts on human …

A&P Workshop Summary—Uniting Anatomy And Physiology Through Case Studies, Angela Horner, Stuart Sumida, Tomasz Owercowicz

Q2S Enhancing Pedagogy

Introducing problem-solving based methods of pedagogy is one approach to engage students early in their careers with developing analytic and diagnostic skills. PBL approaches in anatomy and medical teaching are a logical extension of clinical case studies, wherein an example of a pathology or clinical procedure is provided, and students must ascertain the anatomical and/or physiological basis for it. Students report a deeper understanding of material presented in clinical case studies, as the ‘real world’ relevance and importance is immediately clear (Cliff and Wright, 1996).